DE3066149D1 - Maytansinoids, their production and use - Google Patents

Maytansinoids, their production and use

Info

Publication number
DE3066149D1
DE3066149D1 DE8080103138T DE3066149T DE3066149D1 DE 3066149 D1 DE3066149 D1 DE 3066149D1 DE 8080103138 T DE8080103138 T DE 8080103138T DE 3066149 T DE3066149 T DE 3066149T DE 3066149 D1 DE3066149 D1 DE 3066149D1
Authority
DE
Germany
Prior art keywords
4alkyl
maytansinoids
production
15alkyl
antimitotic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8080103138T
Other languages
English (en)
Inventor
Osamu Miyashita
Hiroshi Hamakoshien-Ju Akimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of DE3066149D1 publication Critical patent/DE3066149D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE8080103138T 1979-06-08 1980-06-06 Maytansinoids, their production and use Expired DE3066149D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7281179A JPS55164685A (en) 1979-06-08 1979-06-08 Novel maytansinoid compound and its preparation

Publications (1)

Publication Number Publication Date
DE3066149D1 true DE3066149D1 (en) 1984-02-23

Family

ID=13500153

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8080103138T Expired DE3066149D1 (en) 1979-06-08 1980-06-06 Maytansinoids, their production and use

Country Status (6)

Country Link
US (1) US4317821A (de)
EP (1) EP0021178B1 (de)
JP (1) JPS55164685A (de)
AT (1) ATE5885T1 (de)
CA (1) CA1135260A (de)
DE (1) DE3066149D1 (de)

Families Citing this family (271)

* Cited by examiner, † Cited by third party
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