DE29724585U1 - Flicken und Kit zur Wiederherstellung von Knorpel - Google Patents
Flicken und Kit zur Wiederherstellung von KnorpelInfo
- Publication number
- DE29724585U1 DE29724585U1 DE29724585U DE29724585U DE29724585U1 DE 29724585 U1 DE29724585 U1 DE 29724585U1 DE 29724585 U DE29724585 U DE 29724585U DE 29724585 U DE29724585 U DE 29724585U DE 29724585 U1 DE29724585 U1 DE 29724585U1
- Authority
- DE
- Germany
- Prior art keywords
- patch
- membrane
- kit
- cartilage
- cover
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 210000000845 cartilage Anatomy 0.000 title claims abstract 12
- 238000011084 recovery Methods 0.000 title 1
- 210000001612 chondrocyte Anatomy 0.000 claims abstract 19
- 230000007547 defect Effects 0.000 claims abstract 5
- 238000002054 transplantation Methods 0.000 claims abstract 2
- 239000012528 membrane Substances 0.000 claims 27
- 230000004888 barrier function Effects 0.000 claims 11
- 230000002439 hemostatic effect Effects 0.000 claims 10
- 239000000853 adhesive Substances 0.000 claims 7
- 230000001070 adhesive effect Effects 0.000 claims 7
- 102000000503 Collagen Type II Human genes 0.000 claims 6
- 102000008186 Collagen Human genes 0.000 claims 3
- 108010035532 Collagen Proteins 0.000 claims 3
- 108010041390 Collagen Type II Proteins 0.000 claims 3
- 102000001187 Collagen Type III Human genes 0.000 claims 3
- 108010069502 Collagen Type III Proteins 0.000 claims 3
- 230000000735 allogeneic effect Effects 0.000 claims 3
- 229920001436 collagen Polymers 0.000 claims 3
- 230000002950 deficient Effects 0.000 claims 3
- 206010007710 Cartilage injury Diseases 0.000 claims 1
- 210000001188 articular cartilage Anatomy 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2/2846—Support means for bone substitute or for bone graft implants, e.g. membranes or plates for covering bone defects
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30756—Cartilage endoprostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00491—Surgical glue applicators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/38—Joints for elbows or knees
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2002/2835—Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/30004—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis
- A61F2002/30016—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis differing in hardness, e.g. Vickers, Shore, Brinell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/3006—Properties of materials and coating materials
- A61F2002/30062—(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30756—Cartilage endoprostheses
- A61F2002/30761—Support means for artificial cartilage, e.g. cartilage defect covering membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30756—Cartilage endoprostheses
- A61F2002/30762—Means for culturing cartilage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
- A61F2250/0019—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in hardness, e.g. Vickers, Shore, Brinell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00365—Proteins; Polypeptides; Degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
Description
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Claims (37)
1. Flicken zur Wiederherstellung von Knorpel, umfassend eine zellfreie resorbierbare
Membran mit poröser Oberfläche sowie Chondrozytenzellen, die an der porösen
Oberfläche der Membran anhaften, zur Verwendung sowohl als hämostatische
Schranke als auch als Flicken zur Abdeckung eines Knorpeldefekts.
2. Flicken nach Anspruch 1, bei dem die Membran aus Collagen ist.
3. Flicken nach den Ansprüchen 1 und 2, bei dem die Membran eine Typ I und Typ III
Collagenmembran ist.
4. Flicken nach den Ansprüchen 1 und 2, worin die Membran eine Typ II
Collagenmembran ist.
5. Flicken nach einem der Ansprüche 1 bis 4, worin die Chondrozytenzellen autolog sind.
6. Flicken nach einem der Ansprüche 1 bis 4, worin die Chondrozytenzellen allogen sind.
7. Flicken nach einem der Ansprüche 1 bis 4, worin die Chondrozytenzellen xenogen
sind.
8. Flicken nach einem der Ansprüche 1 bis 7, zusätzlich gekennzeichnet durch einen an
die Membran angrenzenden biokompatiblen Klebstoff.
9. Flicken nach einem der Ansprüche 1 bis 8, bei dem die Membran derart ausgebildet
ist, um einen Defekt des Gelenkknorpels zu bedecken.
10. Kit für die Chondrozytentransplantation auf die Oberfläche eines Gelenks, das eine
defekten Knorpelbereich aufweist, wobei der Kit umfasst:
- - eine hämostatische Schranke zur Hemmung der Gefäßneubildung und des Einbringens von Zellen in sich entwickelndes Knorpelgewebe,
- - einen Abdeckflicken, der derart ausgebildet ist, um die Oberfläche und die hämostatische Schranke zu bedecken,
- - Chondrozyten, die positioniert sind, um an dem Abdeckflicken zu haften, und
- - einen organischen Klebstoff, der derart ausgebildet ist, um die hämostatische Schranke und/oder den Abdeckflicken an der Oberfläche zu befestigen.
11. Kit nach Anspruch 10, bei dem der Abdeckflicken und die hämostatische Schranke
kombiniert sind, sodass der Kit umfasst:
- eine Kombination aus Abdeckflicken/hämostatische Schranke zum Bedecken des
defekten Bereichs eines Knorpels,
- - Chondrozyten, die vorgesehen sind, um an der Kombination Abdeckflickenlhämostatische Schranke zu haften, und
- - einen organischen Klebstoff.
12. Kit nach Anspruch 10, bei dem der organische Klebstoff in Kombination mit dem
Abdeckflicken als die hämostatische Schranke wirkt und sie dadurch ersetzt.
13. Kit nach den Ansprüchen 10 oder 11, bei dem die hämostatische Schranke, der
Abdeckflicken und/oder die Kombination aus Abdeckflicken und hämostatischer
Schranke aus einer resorbierbaren, zellfreien Membran mit einer porösen Oberfläche
bestehen.
14. Kit nach Anspruch 12, umfassend:
- - einen Abdeckflicken, der derart ausgebildet ist, um die Oberfläche zu bedecken,
- - Chondrozyten, die so plaziert werden sollen, dass sie an den Abdeckflicken haften, und
- - einen organischen Klebstoff, der derart ausgebildet ist, um die Oberfläche zu bedecken.
15. Kit nach Anspruch 14, bei dem der Abdeckflicken derart ausgebildet ist, um das
Anhaften der Chondrozytenzellen an die poröse Oberfläche zu bewirken.
16. Kit nach einem der Ansprüche 12 bis 15, bei dem der Abdeckflicken aus einer
resorbierbaren zellfreien Membran mit einer porösen Oberfläche besteht.
17. Kit nach einem der Ansprüche 13 bis 16, in dem die Membran aus Collagen ist.
18. Kit nach einem der Ansprüche 13 bis 16, bei dem die Membran eine Typ I und Typ III
Collagenmembran ist.
19. Kit nach einem der Ansprüche 13 bis 17, bei dem die Membran eine Typ II
Collagenmembran ist.
20. Kit nach einem der Ansprüche 10 bis 19, bei dem die Chondrozyten autolog sind.
21. Kit nach einem der Ansprüche 10 bis 19, bei dem die Chondrozyten allogen sind.
22. Kit nach einem der Ansprüche 10 bis 19, bei dem die Chondrozyten xenogen sind.
23. Flicken zur Wiederherstellung von Knorpel, umfassend eine resorbierbare zellfreie
Membran, die eine poröse Oberfläche aufweist, sowie Chondrozytenzellen, die an die
poröse Oberfläche der Membran haften, wobei der Flicken derart ausgebildet ist, um
einen Knorpeldefekt zu bedecken.
24. Flicken nach Anspruch 23, bei dem die Membran aus Collagen ist.
25. Flicken nach den Ansprüchen 23 und 24, bei dem die Membran eine Typ I und Typ III
Collagenmembran ist.
26. Flicken nach den Ansprüchen 23 und 24, bei dem die Membran eine Typ II
Collagenmembran ist.
27. Flicken nach einem der Ansprüche 23 bis 26, bei dem die Chondrozytenzellen autolog
sind.
28. Flicken nach einem der Ansprüche 23 bis 26, bei dem die Chondrozytenzellen allogen
sind.
29. Flicken nach einem der Ansprüche 23 bis 29, bei dem die Chondrozytenzellen
xenogen sind.
30. Flicken nach einem der Ansprüche 23 bis 28, der weiterhin angrenzend an die
Membran einen biokompatiblen Klebstoff aufweist.
31. Flicken nach einem der Ansprüche 23 bis 30, bei dem die Membran derart ausgebildet
ist, um einen Knorpelgelenkdefekt zu bedecken.
32. Flicken nach Anspruch 23, der weiterhin einen organischen Klebstoff zum Anhaften
an den defekten Knorpelbereich aufweist.
33. Flicken nach Anspruch 32, bei dem die zellfreie Membran derart ausgebildet ist, um
sowohl als ein Abdeckflicken als auch als eine hämostatische Schranke zu wirken.
34. Flicken nach Anspruch 23, bei dem die poröse Oberfläche derart ausgebildet ist, dass
sie Chondrozytenzellen an einem Rand der porösen Oberfläche anhaften lässt.
35. Flicken zur Wiederherstellung von Knorpel, umfassend eine resorbierbare zellfreie
Membran, die eine poröse Oberfläche aufweist, wobei der Flicken derart konfiguriert
ist, dass er zum Bedecken des Bereichs eines Knorpelschadens geeignet ist.
36. Flicken nach Anspruch 35, der weiterhin derart konfiguriert ist, dass er es gestattet,
Chondrozytenzellen an seiner porösen Oberfläche anzuhaften.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/704,891 US5759190A (en) | 1996-08-30 | 1996-08-30 | Method and kit for autologous transplantation |
US08/857,090 US5989269A (en) | 1996-08-30 | 1997-05-15 | Method, instruments and kit for autologous transplantation |
EP97939677A EP1006950B1 (de) | 1996-08-30 | 1997-08-29 | Nit zur chondrozytentransplantation in einem gelenk |
Publications (1)
Publication Number | Publication Date |
---|---|
DE29724585U1 true DE29724585U1 (de) | 2002-05-16 |
Family
ID=27107401
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69726896T Expired - Lifetime DE69726896T2 (de) | 1996-08-30 | 1997-08-29 | Trägerstruktur für die Chondrozytentransplantation zur Reparatur von Knorpeln und Gelenken |
DE69728569T Expired - Lifetime DE69728569T2 (de) | 1996-08-30 | 1997-08-29 | Kit zur Chondrozytentransplantation in einem Gelenk |
DE69739363T Expired - Lifetime DE69739363D1 (de) | 1996-08-30 | 1997-08-29 | Verfahren zur Herstellung eines Kits zur autologen Transplantation |
DE29724585U Expired - Lifetime DE29724585U1 (de) | 1996-08-30 | 1997-08-29 | Flicken und Kit zur Wiederherstellung von Knorpel |
Family Applications Before (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69726896T Expired - Lifetime DE69726896T2 (de) | 1996-08-30 | 1997-08-29 | Trägerstruktur für die Chondrozytentransplantation zur Reparatur von Knorpeln und Gelenken |
DE69728569T Expired - Lifetime DE69728569T2 (de) | 1996-08-30 | 1997-08-29 | Kit zur Chondrozytentransplantation in einem Gelenk |
DE69739363T Expired - Lifetime DE69739363D1 (de) | 1996-08-30 | 1997-08-29 | Verfahren zur Herstellung eines Kits zur autologen Transplantation |
Country Status (27)
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US (9) | US5989269A (de) |
EP (4) | EP1006950B1 (de) |
JP (3) | JP2002502272A (de) |
KR (2) | KR20030097603A (de) |
CN (2) | CN1500447A (de) |
AT (3) | ATE263524T1 (de) |
AU (1) | AU731162B2 (de) |
BR (1) | BR9711967A (de) |
CA (2) | CA2264138C (de) |
CZ (1) | CZ297248B6 (de) |
DE (4) | DE69726896T2 (de) |
DK (5) | DK1006950T3 (de) |
ES (3) | ES2325206T3 (de) |
HK (2) | HK1025035A1 (de) |
HU (2) | HUP0002980A3 (de) |
IL (1) | IL128580A (de) |
MX (1) | MXPA99001794A (de) |
NO (1) | NO990933D0 (de) |
NZ (3) | NZ334400A (de) |
PL (1) | PL331834A1 (de) |
PT (3) | PT1006950E (de) |
RU (2) | RU2214197C2 (de) |
SG (2) | SG120854A1 (de) |
SI (2) | SI1384452T1 (de) |
SK (1) | SK285075B6 (de) |
TR (3) | TR199900437T2 (de) |
WO (1) | WO1998008469A2 (de) |
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2006
- 2006-03-14 US US11/375,180 patent/US20060195122A1/en not_active Abandoned
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2007
- 2007-06-13 JP JP2007155993A patent/JP2007296371A/ja active Pending
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