DE2131334A1 - Valve arrangement for multiple blood sampling device - Google Patents

Description

Valve assembly for multiple blood sampling device

A valved connector assembly is provided comprising a pair of tubes and one slotted provided, transverse, elastic disk groove part, which is normally the interior of the two tubes separates and breaks the connection therebetween, one of the two tubes being slidable towards and away from the slotted disc subdivision is present for the purpose of mechanical opening and enabling an automatic closing the slot subdivision again. In the embodiment, the other pipe is stationary and the two tubes are pointed at their outer ends for use in a multiple blood sampling arrangement to enable, whereby a detachable vacuum collection container with a rubber stopper is present, which can engage one of the two pointed tubes.

The invention relates to a valved connector assembly and in particular a valved needle connector assembly that allows multiple blood samples to be collected.

For various reasons including the automation of blood chemical analysis and the lower cost of such Analysis, it is now often expedient to take several blood samples starting from a single venipuncture. Bai one such Multiple blood sample collection system, up to 8 samples are occasionally taken during one session, and this is done a suitable venipuncture needle is inserted into a vein and a large number of suitable containers that were usually evacuated Glass ampoules with rubber stoppers are connected, one after the other, separately to the venipuncture needle! In the

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Take such samples with consecutive containers it is expedient that the needle assembly is provided with means that prevent blood flow from the vein in the meantime before and prevented between individual withdrawals. According to the prior art, various valve arrangements have become known for this purpose, however, none of them could completely satisfy them.

For example, one conventional arrangement is a venipuncture needle provide, the thickened end of which is pitted and sealed and there is a side opening in the thickened end portion formed, which is normally closed by a tightly fitted elastic tube, which is like a harmonica lengthways the needle or cannula is pushed back as soon as the sharpened thickened end is in the rubber stopper of a vacuum container for the Blood sampling is introduced. When the needle is separated from the rubber stopper the elasticity of the tube causes it to be returned via the side opening, thereby interrupting the flow of blood will. However, since the blood exits through the side opening at right angles to the tube axis, the blood flow beats on the side wall of the vacuum container at high speed and this causes hemolysis or mechanical destruction which causes blood cells. This is not expedient since it adversely affects the desired analytical results. Since the elastic sleeve can lose its elasticity over time, the desired rapid recovery can continue of the pipe may not be maintained. Furthermore, the desired rapid return of the ice tube is achieved their harmonically folded position in their normal closed position normally by applying considerable amounts of lubricants such as silicone oil and this can adversely affect the chemical analysis of the blood sample. It is also very difficult and expensive to produce pipes that have the necessary tolerance to a complete To effect interruption of blood flow and rapid return of the pipe cuffs. Furthermore, the repatriation leads

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Cuff made of rubber or other elastic material past the side opening in the thickened end of the tube for training a quite large drop due to the shovel-like action of the thickened end of the cuff when stepping past at the side opening on the ducts. The accumulation of these drops when taking 4, 5 or 6 samples is normal sufficient to soil the holder, thereby essentially the purpose of the unit is not achieved, which is this pollution and the resulting danger to the user to prevent.

Another prior art arrangement has a double ended needle arrangement including a single tube or cannula that is tapered at each end, but the thickened end of the The cannula, normally arranged around the same, has an icy loose fitting sleeve which is sealed at its outer end is and can be folded over the thickened end of the cannula, in which connection the thickened end point is the elastic one Cover tube wall perforated and to a connection between the opposite pointed end of the needle or cannula and a container or other device or body which can be penetrated by the thickened end. Even if this The straight-line device for blood flow effectively solves the problem of hemolysis and some of the others with the first described device eliminates associated problems, but the valve arrangement is not satisfactory, since the same must normally be controlled manually by the operator in order to such a renewed closing of the thickened end of the needle by the elastic cover tube when removing the sample container to manufacture from the same.

U.S. Patent 3,494,352 describes the provision of a valved needle assembly with a cannula which is rigidly attached for venipuncture, and there is a second double-ended cannula - i.e. pointed at both ends - and slidably intended for piercing a puncturable and self-sealing subdivision that is normally

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is located between the two cannulas to interrupt the flow of liquid between the two cannulas. However, the double ended slidable cannula is intentionally loose with this arrangement and allows the passage of air from the outside air into any chamber that is the inner pointed end of the contains slidable cannula, whereby air can enter the blood receiving container, while the same herewith

stands. Because of this loose and oversized customization the slidable cannula, this cannula can continue to be easily during the attachment or removal of the container or be rotated in the meantime. With such a rotating displacement movement of the position of the double-ended cannula that a may have tapered tapering inner end, the-

W the same come into contact with the rubber subdivision at different rotational positions and pierce the same, as a result of which a plug is practically cut out of the rubber subdivision. Thus, after two, three or more penetrations of the rubber subdivision by the needle having a double bit, this subdivision may no longer interrupt the passage of liquid through the subdivision when the double-ended, slidable needle is removed therefrom. In some embodiments according to this publication it has been found that only one or two punctures of the subdivisions by the double-ended cannula have resulted in such destruction of the disk groove that the subdivision was completely reclosed and sealed

b is prevented when removing the double-ended cannula, so that the Fluid flow no longer occurs when the double-ended cannula is removed is interrupted from the subdivision. This device is also difficult to use because the apparently necessary thick subdivision and associated surrounding arrangement according to the disclosure made there make it quite difficult to subdivide to break through or puncture the sliding cannula.

It represents an essential object of the invention, an improved one to provide valved connection assembly which is particularly well adapted to the fact that multiple blood samples or samples of another corresponding liquid can be taken and a complete under-

interruption of blood flow allows.

Another object of the invention is to provide an improved To create valve arrangements that normally do not allow two interconnecting pipes selectively connect to or from each other in a flow relationship Separate flow ratio, wherein the valve assembly does not require a piercing tip for the formation of the Apply fluid connection.

Another object of the invention is to to provide a multiple blood sampling assembly having two relatively movable needles or cannulas, first and are usually not in fluid communication with each other, and here the adjacent ends of each of the two cannulas are usually in connection with corresponding ends of the individual chambers, which are also not in fluid communication with one another, and the liquid interruption is accomplished by means of a slotted partition unit having pre-formed lips which are normally resiliently held adjacent one another, and sliding movement of one of the cannulas causes the lips to open the dividing unit by connecting the two cannulas and the two chambers, the two chambers facing the outside air with Except for the corresponding central bores of the corresponding cannulas are sealed, eliminating any unsuitable air pollution or air bubbles in the liquid sample is avoided, for example by means of an air passage around the circumference of the slidable Cannula around is effected.

An embodiment of the invention is shown in the drawings and is described in more detail below. Show it:

1 shows a perspective view of a multiple blood sampling device according to the invention, prepared for use of the same;

Fig. 2 is a longitudinal section through the main part of the embodiment according to Figure 1;

3 shows a broken away longitudinal section in perspective enlarged view for the purpose of better explanation of the valve elements;

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Figure 4 is a diagrammatic view with certain parts in phantom and some parts are omitted for clarity of illustration and explain the essential valve parts of the embodiment according to Figures 1 to 3 and the embodiment shown here in the normal locking position for the liquid;

4a shows a schematic longitudinal section on an enlarged scale and parts according to FIG. 4, specifically along the line 4a-4a according to FIG. 4b;

Figure 4b is a transverse diagrammatic view of the slotted disc subdivision and associated elements, along the line Line 4b-4b according to Fig. 4a, the hub being shown in dashed lines as in each of FIGS. 4 and 4a for the sake of clarity is;

5, 5a and 5b, in a corresponding manner, show a perspective, cross-sectioned longitudinally and diagrammatically on the transverse side View, partly for the purpose of clear illustration, similar to that shown and explained in dashed lines according to FIGS. 4, 4a and 4b opening the slotted disc groove by means of the blunt-ended slidable cannula;

Figures 6, 6a and 6b are diagrammatic views similar to those of FIG Figures 4, 4a and 4b, 5, 5a and 5b and show the corresponding positions of the two cannulas and the slotted disc subdivision in the fully open position;

Figure 6c is an enlarged diagrammatic representation of a portion of the top corner portion of the disc divider slot lips and adjacent cannula wall, specifically within the corresponding right-angled position according to FIG. 6;

7, 7a and 7b show similar designs as in FIGS. 4, 4a and Figures 4b and 4b show diagrammatically one possible normal configuration of the slotted disc partition after removal of the slidable cannula therefrom and reclosing the slot;

8 to 10 different locking configurations of the slotted Disc subdivision after removing the sliding cannula from the same.

Based on the drawings, the subject of the invention is in the form a multiple blood sampling device 11 is explained, which has a valve-provided needle connection arrangement 21, which is detachably connected to a syringe body 51 for the purpose of facilitating the successive connection of the arrangement 21 with multiple blood collection vessels 61, as shown generally in FIG Figure 1 is shown in preparation for the attachment of the blood collection vessel.

The arrangement 21 in the embodiment shown here has a Hub 25, which can be made of a malleable metal such as aluminum, and it is a hollow venipuncture cannula or Needle 23 rigidly attached to its front or nose end, for example by means of crimps as at 25c. The cannula 23 can with a appropriately sharpened end 23a, e.g. by means of a tapered point, as is otherwise customary is. There may be a protective cover 24 - or covers made of plastic or other suitable material releasably over one Frictional adhesion to be attached to the hub 25 for the purpose of protecting and establishing hygienic conditions prior to use in the form of desired venipuncture and blood collection.

The hat 21 can be detachably attached to the hub end 52 of the syringe body 51 in a suitable manner, e.g. by means of hub connecting wings 25h which are releasably inserted into the wing-receiving bayonet slots 53a ¹ which are formed on the front or nose end wall 53 of the syringe body and extend radially outward from the hub receiving central bore opening 53a formed in the front wall 53. As is the case with conventional bayonet slot connections, the wing receiving bayonet slot 53a ¹ can be rotated laterally by 90 ° to form a connection with fastening slots, whereby a fastening of the wings connecting the hub by inserting the hub 25 with the wings 25h in the bore opening 53 and slots 53a ¹ and rotating the hub 21 by 90 ° is enabled. As a support for maintaining the friction of those connected to the hub

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Wing 25h inside the slot 53a ¹ an elastic retaining ring 33 is provided, which is suitably made of plastic, rubber or the like. The same forms and delimits the rear wall of the slots 53a ¹ , whereby a perfect adjustment and fixing for the wings 25h is reached. The retaining ring 33 may be suitably secured in place by an inwardly turned circumferential friction lip 53h on the rear surface of the front wall 53. ^v

The arrangement 21 also has a second cannula 31, which for puncturing and forming fluid communication with a suitable collection device is used, which is preferably a suitably evacuated vacuum collection vessel 61. Same may be in the form of a glass ampoule 63 which has a rubber stopper having. Such an evacuated container is well known in the art.

The cannula 31 and the cannula 23 are normally in one separate relationship to one another, and this hindering a flow Ratio is effected by a slotted rubber partition 27 which is provided by a pre-slotted disc is formed. This disc is on the transverse side inside the hub 25 attached by means of a sleeve-like sealing element 29. As can be seen from FIGS. 2 and 3, the inner end 23b of the anterior or venipuncture cannula 23 ends in the interior of a Chamber formed inside the hub 25 and tapered by a front, wall 25b and the front surface of the slotted Rubber washer subdivision 27 is limited. The cannula 31 ends with its inner end 31b in the normal retracted position Location inside a chamber defined by the front, inner, tapered wall of the sleeve-like seal 29 and the intermediate rear wall of the slotted rubber washer 27 is formed. This chamber is usually practically complete both sealed off from the front chamber adjacent to the end 23b of the cannula 23 and from the outside air. For that purpose is the slotted disc 27 inside the hub 25 by the compressive annular pinching of the disc 27 against the shoulder 25a in the hub 25 by the annular, front, tapered one Nose 29b set, thereby effectively removing the disc 27

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is held in place and forms a hermetic seal between shoulder 25a and nose 29b. Farther is the bushing 29 with a rubbing guide surface and sealing portion 29c provided a relatively short length, which effectively .samer the inner end 31b and the bore 31c of the cannula relative to the outside air or environment around the outer or thickened end 31a of the cannula 31. This sealing of the sealing portion 29c can be easily accomplished by that this sealing section with a slight undersize with the formation of a fit with oversize together with the cylinder-shaped outer surface 3led of the cannula 31 is formed.

The seal 29 can be implemented in a suitable manner inside the hub 25, for example by flanging or notching the annular wall of the hub around or at intervals around the circumference thereof, see reference number 25g, whereby the seal is anchored inside the hub 25. Before and during this flanged fastening of the seal 29 d inside the hub 25, it is expedient that the seal 29 is pressed forward, the nose end 29b of which is clamped into the rear wall of the disk 27 under pressure, the flange 25g of the hub to that effect acts to anchor the seal 29 together with the washer 27 which is compressed against the shoulder 25h by the annular nose 29b of the seal. With the provision of the slotted rubber washer 27 with approximately 40 to 50 durometers, a thickness of approximately 0.75 mm and a diameter of 4.0 mm and a diameter of the annular nose 29b of 3.2 mm and a transverse radius of curvature of the nose of approximately 0, 05 mm, it has been found that an axially compressive force of approximately 1.5-2.5 kg acting on the seal 29 towards the front end of the hub 25 leads to the desired degree of pinching of the rubber washer 27, which is tapered Bushing nose 29b and the shoulder 25a leads.

The socket seal 31 can be made in a suitable manner from an acetal plastic, such as the plastic known under the trade name Delrin or made of nylon or other relatively durable plastic be manufactured, albeit Acetel plastic due to its high strength values at high temperature and the low Coefficient of friction of this material compared to stainless steel

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from which the slidable cannula 31 is normally made, and the further property of the acetel plastic the dimensional Stability under different storage conditions appears to be most suitable.

The shoulder 25a should have a sufficient width to result in a sufficient seating and sufficient sealing surface. It has been found that a reliable seating or resting of the manufactured from plastic seal 29 annular relatively sharp with one or annular nose end 29b can be accomplished that comes with the sliced in the zone in contact, approximately behind the center to the inner edge the shoulder 25a lies. Given an inner diameter of the larger portion of the hub 25, for a washer ™ 27 with a thickness of approximately 0.75 mm and an outer diameter of approximately 4.0 mm, a suitable diameter of the tapered socket nose 29b is 3.2 mm. The dimensions are suitable for the diameter of cannula tubes of approximately 0.9 mm.

The slotted disc partition 27 is provided with a diametrically extending slot 27a formed, for example, by cutting with a sharp knife, and the lips 27aa of this slot are normally held in close proximity to each other by the elastic nature of the rubber material forming the partition 27. It has been found that ethylene-propylene rubber has proven to be the material for the disk partition to be satisfactory, in particular because DAS w same sterilization heat resisting when it niht the best mechanical properties. In the small sizes of the embodiment shown here, silicone rubber has been found to have insufficient mechanical strength to withstand penetration through the end of the cannula without some tearing. Other rubbers with better mechanical properties can be used and this includes natural rubber and other synthetic rubbers, although most of the other such rubbers require the use of gas sterilization or chemical sterilization rather than heat sterilization due to the deterioration in their properties due to what is normally used

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coming high sterilization temperatures. When a gas sterilization or chemical sterilization is acceptable in a given case or when another sterilization is sufficiently effective is or if sterilization is not required, it is understood that such other rubber compounds or others elastic materials with better mechanical properties can be used in such cases. The slot 27a extends partially through the annular inner surface zone formed on shoulder 25a. As far as the shoulder 25a has an outer diameter of approximately 3.98 mm and an inner edge diameter of approximately 2.5 mm and furthermore a disc 27 made of ethylene-propylene rubber with a diameter of approximately 3.98-4.00 mm and a thickness of approximately 0.70 0.76 ram is present, as well as the outer diameter 37d of the cannula 31 at its inner end starting from the cylindrical outer diameter of 0.9 mm to an outer diameter of 1.05 mm widened, it was found to be approximately 0.235 mm represents a suitable transverse length for slot 27a.

The cannula 31 is axially slidable inside the seal 29 in the direction of and away from the slotted disc 27 for the purpose Effecting opening of the slotted lips 27aa during an intermediate arrangement of the same inside the lips and automatic renewed closing of the lips 2 7aa after they have been pulled out of the cannula 31 from between the lip 27aa and away from the Washer 27. To prevent the slidable cannula 31 from being pulled out of the socket seal 29, the inner end of 31b is the slidable cannula widened running tapered by means of a corresponding tool. As stated above, has in an exemplary embodiment using a Tube for the cannula 31 with a diameter of 0.9 mm a widening of the end 31b to an outer diameter of 1.05 mm proved to be satisfactory. Even if a symmetrical widening, as shown here, is appropriate, it was found that that this is not necessary for the purpose of holding the cannula 31 on

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Place and accomplish the desired opening and closing of the disk subdivision 27. The widened end 31b can be slightly rounded on its outer circumferential edge surface, in order to support a smoother opening of the slot 27a and a possible surface abrasion as a result on the disk 27 during the to reduce opening of the slot 27a. Although other stop arrangements causing a retention can be formed on the cannula 31, e.g. by attaching or forming a flange behind the inner end 31b _f , these possibilities are normally expensive and less expedient than the simple widening stop end shown here.

The outer, opposite or widening end 31a of the cannula 31 is designed in a suitable manner with a pointed tip for penetration of the rubber stopper 65 which is fastened in the end of the ampoule 63. For this purpose, the tapering end 31a can be designed in a suitable manner, see FIGS. 1 and 2, by means of first forming an obliquely tapering point and then bending it in the direction of the central axis of the needle.

In use, see Figures 4-7 in connection with the Figures 1 and 2, the venipuncture cannula 23 is inserted into the vein of the patient, the sliding cannula 31 in the normal or closed position, see Figures 1-4. After the cannula 23 is present in the patient's vein, the evacuation ™ is activated te blood collection container 01 is moved to the front end of the syringe body 51, whereby the rubber stopper 65 in contact with the with Pointed thickened end 31a of cannula 31 is brought.

The further forward movement of the container 61, below Holding the syringe body 51 causes the thickened tip 31a to embed itself in the rubber stopper 65, whereby the open thickened End of the cannula 31 is closed. This also the forward movement of the slidable cannula in the direction of the Disc subdivision 27 started, whereby the disc subdivision 27 comes into contact with the enlarged inner end 31b of the cannula 31.

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The continued forward movement of the container 61 causes the enlarged inner end 31b of the cannula 31 to meet the lips 27aa of the. 5, 5a and 5b, and the cannula 31 then continues its movement between the separate lips 27aa until its inner end 31b comes into contact with the intermediate end 23b of the stationary cannula 23. There is thus a fluid connection between the corresponding inner bores 23c and 31c of the two cannulas 23 and 31 immediately when the lips are opened, see FIG. 5, and also in the foremost position of the cannula 31, see the FIGURE split lips generally have the appearance of a cat's eye and are positioned generally protruding forwardly towards the cannula 23 in the open position. Normally there will be a small eye opening 27abc which is present between the adjacent split lips 27aa at the junction immediately adjacent to the outer cylindrical, annular surface 31d of the cannula and the lap corner junction zone. This small eye opening can be quite tiny as the lips 27aa tend to contact each other along a substantial length thereof adjacent zn to remain the slit of the outer corner, as taken along the line shown in the Figure 6c 27ab. It has been found, however, that there is normally a small eye opening, see reference numeral 27ab, on both sides of the tube at the corner connection of the tube wall 31d with the lip interface, and this small eye opening can be approximately 0.025-0yl3 mm for the one shown here for example general size range. With a slight retraction of the cannula end 31b in the direction of the disc division 27, the protruding part of the lip 27aa will generally disappear and the small eye opening 27abc may tend to be larger. With regard to the practical hermetic seal around the circumference of the rubber washer subdivision 27 by means of the shoulder 25a and the tapered socket nose 29b on the one hand and the interference with the oversize of the sealing section 29c with the outer cylindrical surface 3id of the cannula 31 on the other hand, the fluid connection between the two influences two chambers on each side of the disc divider 27 through the small eye opening 27abc

not the connection of the bores 23c and 31c of the cannulas opposite the

In a sliding of the cannula 31 forward to the position shown in the Figure 6 position, and abutting, on the opposite adjacent end 23b of the ortsfestall Kanülo 23 EIIS continued forward movement of the container is Sl in Richtimg the rabbit end of the syringe body zn © inest corresponding further penetration of the Guide the cannula 31 into and through the stopper 65. After the open, pointed end 31a of the cannula emerges into the interior of the glass ampoule 63, the complete fluid connection between the patient and the interior of the glass ampoule 63 due to the now connected cannula 23 vina 31 is brought about distance through the evacuated, eggs glass ampoule 63 is & num ore ü & b blood through the cannulas 23 and 31 in dia glass ampoule S3 filieSsiic

As soon as the desired blood volume has been collected in ä & g glass ampoule 63? it is only necessary for the operator-the container 61 vun the SpritseaköKper 51 saröckf ".Pull by interrupting blood flow äusah the cannulas 23 and 31! 'Jährend the initial Zurüefesieheas ä & m Bsfaälfcars 61 is the friction resisting stand between the cannula 31 and the rubber plug 65 influence the movement of the cannula 31 with the stopper 65, as a result of which the cannula 31 slides backwards through the slot 27a in its initial rest position, as shown in FIGS. 1-4 and 7. The further k retraction of the container 61 leads to the stopper being pulled off and separated from the slidable cannula 31. However, since the cannula 31 has already been moved into its rearmost position, the slot 27a is then closed again under the self-closing elastic effect of the Guirani disk subdivision 27. The valve-provided needle connection arrangement 21 is thus again in the closed state and prepared for a connection with a further blood container 61 before, while performing the same work steps described above with respect to the connection and the detachment of the container. Successive individual blood samples can thus be taken with an individual evacuated container 61 or other suitable containers or receptacles without the loss of blood through the

Needle connection assembly within the time periods before, between or after the samples have been taken.

Even if the slot 27a is in a position practically that after Fig. 4, can close again, the two opposite surfaces of the disk subdivision 27 being substantially flat are, as well as the lips 27aa essentially in their original coplanar position have been traced back, this is not always the case, since in some cases different slightly different configured return positions of the lips 27aa in the closed position of the same when the widened end 31b of the cannula 31 is withdrawn therefrom. One such a shape is shown schematically in Figures 7, 7a, 7b and 8, the slot tending to form some kind of dimple on its front surface and a corresponding minor one Surface elevation in the zone of the slot 27a on the rear surface adjacent to the cannula 31 is formed. Still are effectively closing lips 27aa in such a case and are in close abutment with each other and the desired fluid disruption between cannulas 23 and 31 is achieved below complete interruption of the flow of liquid, such an elevation or depression in the slit of the disc surface the front surface should be the result of pulling out the widened End 31b of the cannula 31 and the slightly different Springing back or rebounding as it arises between the two lips once the flared end of the slit lips 27aa leaves.

Further occurring conditions of reclosing the lips 27aa are shown in FIGS. The resulting configuration according to Figures 3 and 10 can be through a uneven or asymmetrical formation of the widened end 31b result. Despite the slight lead or asymmetrical design of the again closed lips 27aa, but they lie in a closely adjacent opposite one and adjoining relationship in this re-closed state and thus cause the desired liquid seal.

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In this regard, the liquid closure of a control valve normally considered effective for the purpose of blood sampling when the valve has a pressure differential of an- » approximated -10 cm water column withstands. The embodiment shown here as an example has proven to be complete for this purpose proven to be sufficient and can in practice have significantly higher pressure differences for this and other purposes, by appropriately varying the thickness and size of the valve divider 27 and the other associated parts takes place. Thus, while the subject matter of the invention is particularly in the medical field for taking a plurality of blood samples from thner single venipuncture is applicable and is used in particular, the subject matter of the invention also proves to be one The valve assembly is suitable for general purposes and can also be used for other medical applications which require selective valve closure. In this regard, the sliding function of the cannula or tube 31 in other corresponding ways than by the intercoupling of the same with respect to an ampoule stopper, e.g. by means of manually moving the cannula forwards and backwards. In such a case, the cannula 31 can form a simple tube, which as such is connected to another liquid source or outlet point via a rigid or flexible pipe, and which The cannula 23 can optionally be sharpened in such a case, as dictated by the corresponding circumstances.

It has been found / that the provision of a single rectilinear slot is substantially superior to other possible slot configurations in the subject invention, since other configurations are not tend to close completely and also show further mechanical disadvantages. The most expedient and successfully applied The shape of the slot is formed by two adjacent and opposite slit lips which come into contact with one another resiliently returned to this opposing, contacting relationship upon withdrawal of the slidable cannula.

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Variations and modifications can be carried out in accordance with the invention e.g. in addition to the modifications explained above, the one formed by the two pipes and the separating sludge partition general valve design can also be used in other configurations and for purposes other than those explained here. While in the embodiment shown here, a wing connection 25 h is used for connecting to a bayonet slot opening, a hub 25 or other housing with respect to the arrangement 21 be used, which is a different way of connecting with the Has syringe body or other unit. for example, the hub assembly may have an internally threaded portion at the rear end for a Have thread engagement with a complementary and external thread having opening in a syringe body or the like.

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Claims (1)

Claims Valve arrangement for multiple blood sampling devices or the like, characterized in that a housing (51) with a cavity therein, a first and a second cannula (23,31) in connection with the housing (51), each of which is an open one End (23a, 31a) in fluid communication with part of the cavity, an elastic partition (27) in the housing cavity, which normally separates the cannulas (23,31) with respect to the flow connection, the partition (27) being a pre-formed, self-closing , has transverse slot (27a) extending through the same and has opposite normally abutting lips (27aa) for the passage and reception of one of the cannulas (31) for the purpose of forming a flow connection between the cannulas (23,31), one of the cannulas ( 31) longitudinally slidable towards and away from the partition (27) and generally longitudinally aligned with the preformed one Slit (27a) is present, the slidable cannula (31) has a blunt end (31b) which, inside the cavity, can be movably and selectively brought into engagement with the partition (27) in the zone of the slot (27a) so that the normally closed lip (27aa) of the slot (27a) in the partition (27) can be laterally separated and opened as a function of the longitudinal sliding movement of the cannula (31) towards and into engagement with the lips (27aa) separating Subdivision (27), the lips (27aa) of the subdivision slot (27a) being designed to be elastically self-closing when the cannula (31) is moved longitudinally away from the subdivision (27). 2. Device according to claim 1, characterized in that the a cannula (23) is arranged stationary with respect to the housing (51). 3. Device according to claim 1, characterized in that at least one _y of the cannulas (23) is a pointed eye a punk ti- ··; ran. «end at its outer end (23a). ^109887/8 I ΐ S3 4. Apparatus according to claim 3, characterized in that both Cannulas (23,31) have a pointed end which causes puncturing have at their outer ends (23a, 31a). 5. Apparatus according to claim 4, characterized in that the cannula (23) is arranged stationary with respect to the housing (51). 6. Apparatus according to claim 1, characterized in that the slidable cannula (31) has a transversely extending stop formed thereon and arranged inside the cavity for the purpose of limiting the longitudinal movement of the cannula (31). 7. Apparatus according to claim 6, characterized in that the stop is a widening of the blunt inner end of the cannula (31) is. 3. Apparatus according to claim 7, characterized in that the cannula enlargement in the form of an outwardly widening The end (31b) of the cannula (31) is present. 9. The device according to claim 1, characterized in that the slot (27a) is linear and due to the separation due to the passage of the cannula (31) through it, it assumes the shape of a cat's eye. 10. The device according to claim 9, characterized in that the cat's eye-like slot opening has lateral openings on opposite sides Forms sides of the cannula (31). 11. The device according to claim 10, characterized in that the housing (51) has a socket part (29) which has a closely fitted Cuff seal around the Kanüae (31) for a sealing Forms sliding friction fit between the same, the housing (51) is formed practically in one piece with the other cannula (23). 12. The device according to claim 10, characterized in that a liquid collecting container (63) under vacuum in a Fluid connection can be made with the slidable cannula (31), the slidable cannula (31) in seal on and away from the partition (27) slides as a function of the connection and disconnection thereof with the container (63). - 19 - 109887/1153 BATH ORIGINAL 13. The device according to claim 1, characterized in that the pre-formed slot (27a) has a rectilinear configuration has parallel opposing and in contact with one another lips. 14. Valve arrangement, characterized in that first and second pipe segments with normally present in the spacing ratio, oppositely arranged, adjacent ends, a dividing unit with a pair of pre-formed normal- " wise contacting lips which are resiliently urged to their normal contacting position, the dividing unit are arranged between the mutually opposite adjacent ends of the pipe segments and optionally breaking or releasing a flow connection between the pipe segments as a function of severing or occluding the subdivision unit lips, with the first tube longitudinally slidable towards and away from the partition unit is present with selective opening and enabling again Closing the lips of the same. 15. The arrangement according to claim 14, characterized in that the dividing unit formed a pre-formed slot therein has », the laterally opposite one another and in Touching lips form the resiliently pressurized and normally in contact lips. 16. The arrangement according to claim 15, characterized in that the subdivision unit is an elastic subdivision, so that the Lips are self-closing. 17. The arrangement according to claim 16, characterized in that the pre-formed slot has a transverse rectilinear configuration with parallel lips that are opposite and in contact with one another. 18. An arrangement according to claim 14, characterized in that the first slidable pipe segment has a stop formed thereon limiting longitudinal movement thereof with respect to the second tube. - 20 - 1 09887/11 S3 19. The arrangement according to claim 18, characterized in that the Stop an outwardly widening part of the end of the . represents the first pipe segment adjacent to the subdivision unit. 20. Arrangement according to claim 14, characterized in that at least one of the tube segments has a pointed and puncturing end at its outer end which extends away extends from the subdivision unit. 21. Arrangement according to claim 20, characterized in that both pipe segments have pointed ends which extend from the subdivision extend his unit away. 22. Valve arrangement, characterized in that first and second pipe segments, an elastic subdivision, which is transverse extends to and between the pipe segments and has a self-closing, pre-formed transverse slot which Pipe segments are normally separated by the partition at their adjacent ends, the first pipe segment longitudinally slidable toward and away from the second tube and slidable through the slot causing an opening Slit while the same extends through the slit and allow it to close automatically again the slot upon withdrawal of the tube therefrom by means of a movement in a direction away from the second tube segment, are provided. - 21 - 109887/1153