DE19512066A1 - Stent for transluminal implantation e.g. blood vessels - Google Patents

Stent for transluminal implantation e.g. blood vessels

Info

Publication number
DE19512066A1
DE19512066A1 DE1995112066 DE19512066A DE19512066A1 DE 19512066 A1 DE19512066 A1 DE 19512066A1 DE 1995112066 DE1995112066 DE 1995112066 DE 19512066 A DE19512066 A DE 19512066A DE 19512066 A1 DE19512066 A1 DE 19512066A1
Authority
DE
Germany
Prior art keywords
partic
blood vessels
stent
support
apertures
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE1995112066
Other languages
German (de)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Variomed AG
Original Assignee
Variomed AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Variomed AG filed Critical Variomed AG
Priority to DE1995112066 priority Critical patent/DE19512066A1/en
Priority to DE1995116191 priority patent/DE19516191A1/en
Priority to ES96104982T priority patent/ES2119527T5/en
Priority to DE59600411T priority patent/DE59600411D1/en
Priority to EP96104982A priority patent/EP0734698B9/en
Priority to DK96104982T priority patent/DK0734698T4/en
Priority to AT96104982T priority patent/ATE169484T1/en
Priority to US08/624,294 priority patent/US5876449A/en
Priority to JP11288496A priority patent/JP3168531B2/en
Publication of DE19512066A1 publication Critical patent/DE19512066A1/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/9155—Adjacent bands being connected to each other
    • A61F2002/91558—Adjacent bands being connected to each other connected peak to peak
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0004—Rounded shapes, e.g. with rounded corners
    • A61F2230/0013—Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped

Abstract

For transluminal implantation in hollow organs, such as blood vessels, urethra etc., a stent comprises a tubular body (1) which can be put in an expanded state and has apertures (3,4) in both longitudinal and circumferential directions to ensure expansion. Each aperture has at least one section (3',3",3"') which is positioned at an angle to the longitudinal axis in both compressed and expanded state. The apertures form slot-like openings with several, partic. three sections which are inclined to the longitudinal axis. The apertures may be zig-zag shaped, Z-shaped, S-shaped or partic. sinusoidal. The body is pref. of memory metal, partic. Nitinol, and/or body-compatible plastic, partic. PE, PA, or PUR elastomer.

Description

In der medizinischen Technik werden zunehmend röhrenförmige Implantate verwendet um durch Ersatz oder durch Unterstützung bei krankhaft verschlossenen kanalikulären Organen die Funktion wieder herzustellen. Dadurch können krankhaft verschlossene Organe, wie Arterien, Venen, Gallengänge, Magen-Darmteile oder Bronchien, nach der Rekanalisation funktionell offengehalten werden, die sich sonst durch den weiterhin bestehenden obstruierenden Krankheitsprozeß wieder verschließen würden.In medical technology, tubulars are becoming increasingly common Implants used around by replacement or by support the function in pathologically closed canalicular organs restore. This can cause morbidly closed Organs such as arteries, veins, bile ducts, gastrointestinal parts or bronchi, functional after recanalization be kept open, which would otherwise continue through the existing obstructive disease process again would close.

Um diese Implantate wenig invasiv, perkutan in den Körper einzubringen, d. h. ohne große Operation, müssen diese mit einem möglichst kleinen Durchmesser mit katheterartigen Instrumenten in den krankhaften Verschluß eingelegt werden, um dann in einem zweiten Schritt, auf den größeren, röhrenförmigen Funktionsquerschnitt gebracht zu werden. Hierzu stehen passiv durch Grüntzig-Ballonkatheter zu entfaltende Edenstahlgitter oder Tantal-Draht-Geflechte zur Verfügung. Daneben gibt es selbständig entfaltende Stützen aus einem sich überkreuzenden Drahtgeflecht und solche aus einer Nickel-Tantal-Aluminium-Legierung (Nitinol) mit unterschiedlichen thermischen Verhalten, die in kaltem Zustand in einen Katheter verpackt implantiert werden und nach Freisetzung durch die Körperwärme sich selbstätig auf einen größeren Durchmesser erweitern.To make these implants less invasive, percutaneously in the body to bring in d. H. without major surgery, these must be done with a smallest possible diameter with catheter-like instruments be inserted into the pathological closure, and then in a second step, on the larger, tubular functional cross section to be brought. Passively through Grüntzig balloon catheters unfolding Eden steel mesh or tantalum wire mesh for Available. In addition, there are independently deploying supports a crossing wire mesh and those from one  Nickel-tantalum aluminum alloy (Nitinol) with different thermal behavior when cold packed into a catheter and implanted after Release by body heat automatically on you expand larger diameter.

Auch bei den selbständig expandierenden Stützen ist es in der Regel erforderlich, eine Ballondehnung nach der Einführung durchzuführen, 1. um die elastischen Kräfte des Obstruktionsprozesses zu überwinden und 2. um eine möglichst glatte innere Oberfläche zu erreichen. Letzteres ist bei Blutgefäßen besonders wichtig, da hierdurch auch die Abscheidung von Blutgerinseln (d. h. die Thrombogenität des Fremdimplantats) abhängig ist. Das Material der Stütze (hier als endovaskuläre Prothese) beeinflußt ebenfalls die Thrombogenität, so hat offenbar Nitinol bessere Voraussetzungen als Edelstahl.It is also in with the independently expanding supports Usually required balloon expansion after insertion carry out, 1. to the elastic forces of the To overcome the obstruction process and 2. to get one if possible to achieve smooth inner surface. The latter is with Blood vessels are particularly important as this also causes the Separation of blood clots (i.e. the thrombogenicity of the Foreign implant) is dependent. The material of the support (here as endovascular prosthesis) also affects the Thrombogenicity, so Nitinol apparently has better Requirements as stainless steel.

Die Konfiguration, Länge, aktive und passive Expandierbarkeit sowie Verkürzungen bei der Implantation sind bei der Positionierung im Gefäßsystem wichtige technische Parameter. Die passiv durch Ballonkatheter zu implantierenden Systeme können nur in kurzen Längen eingesetzt werden, sind relativ starr im Fall der Edelstahlgitter oder passiv leicht zu deformieren im Fall der Tantal-Drahtgeflechte. Bei den selbst expandierenden treten über längere Abstände erhebliche Verkürzungen auf, die relativ unkontrolliert sind, so daß die Positionierung sehr schwierig sein kann.The configuration, length, active and passive expandability as well as reductions in implantation Positioning in the vascular system important technical parameters. The systems to be implanted passively through balloon catheters can only be used in short lengths, are relatively rigid in the case of stainless steel grilles or easily deformable in the passive Case of tantalum wire mesh. With the self-expanding Significant reductions occur over longer distances are relatively uncontrolled, so the positioning is very can be difficult.

Die selbst expandierenden Nitinol-Stützen besitzen die vorgenannten Nachteile nicht. Mit dem Laser werden aus einem Rohr hierzu Schlitze ausgeschnitten, die bei der nachfolgenden Aufweitung eine rautenförmige Konfiguration ergeben. Zur Erreichung von lateraler Flexibilität und Kurvengängigkeit sind nicht durchgehende zahlreiche Lücken eingebaut. Problematisch ist hingegen, daß die spitzen Rautenenden in diesen Lücken bei enger Kurvenimplantation Knicke mit Verhaken verursachen können und unter Umständen schwere Komplikationen durch Ballonaufspießung bei der nachfolgenden Dehnung zur Glättung der inneren Oberfläche und zur Erreichung des endgültigen Arbeitsdurchmessers verursachen.The self-expanding Nitinol supports have them not the aforementioned disadvantages. The laser turns one To do this, cut out the slots in the tube that are shown in the following Expansion results in a diamond-shaped configuration. For Achieve lateral flexibility and maneuverability numerous non-continuous gaps built in. Problematic is, however, that the pointed diamond ends in these gaps tight curve implantation cause kinks with hooking can and may have serious complications Balloon impaling during the subsequent stretching for smoothing the inner surface and to achieve the final Cause working diameter.

Literaturübersicht in: Stents- State of the Art and Future Developments. Ed.: D. Liermann, Polyscience Publications, Inc. Canada, 1995.Literature review in: Stents- State of the Art and Future Developments. Ed .: D. Liermann, Polyscience Publications, Inc. Canada, 1995.

Der im Patentanspruch 1 angegebenen Erfindung liegt das Problem zugrunde, die Vorzüge der Nitinol-Stützen ohne die Risiken zu erreichen, die durch die spitzen, scharfkantigen Rautenenden in den erforderlichen Lücken zur Erreichung der erforderlichen Flexibilität bisher gegeben waren. The invention specified in claim 1 is Underlying problem, the merits of the Nitinol supports without the Reaching risks through the pointed, sharp edged Diamond ends in the gaps required to achieve the necessary flexibility was previously given.  

Dieses Problem wird durch die im Patentanspruch 2 aufgeführten Merkmale einer durchgehenden röhrenförmigen Gesamtstruktur mit sinuswellenartigen Längskomponenten gelöst, die nur an den Berührungspunkten unterschiedlich versetzt, verbunden sind.This problem is caused by those listed in claim 2 Characteristics of a continuous tubular structure solved with sine wave-like longitudinal components that only on the Points of contact offset, connected differently.

Die mit der Erfindung verbundenen Vorteile bestehen insbesondere darin, daß bei guter Längsstabilität durch die sinuswellenartige Konfiguration und die unterschiedliche seitliche Verbindung ohne Überkreuzungen eine gute laterale Flexibilität gewährleistet wird und scharfkantige End- und Zwischenstrukturen vermieden werden. Dadurch gibt es keine Verhakungen oder Knicken in engeren Kurven und vor allem keine Ballonaufspießungen bei der abschließenden, in der Regel obligaten Ballonnachdehnung. Dies verbindet die für eine geringe Thrombogenität in Blutgefäßen günstigere Nitinoleigenschaften mit der besseren inneren Oberfläche nach der Ballondehnung ohne zusätzliches Risiko. Ohne Vermeidung von spitzen inneren und äußeren nachteiligen Strukturen kann dieses röhrenförmige wabige Gitterwerk ebenfalls besser für weitergehende Anwendungen durch Beschichten mit Kunststoffen oder Medikamenten oder textilen Geflechten benutzt werden, z. B. als endovaskuläre Prothese zur Behandlung krankhafter Aufweitungen A oder Defekten.The advantages associated with the invention exist especially in that with good longitudinal stability through the sine wave configuration and the different side Connection without crossings good lateral flexibility is guaranteed and sharp-edged end and Intermediate structures can be avoided. So there is none Snagging or kinking in tight bends and most of all no balloon skewers at the final, usually mandatory balloon expansion. This connects those for a minor Thrombogenicity in blood vessels has more favorable nitinol properties with the better inner surface after balloon expansion without additional risk. Without avoiding pointed inner ones and external disadvantageous structures, this can be tubular honeycomb lattice work also better for further Applications by coating with plastics or Medicines or textile braids are used, e.g. B. as endovascular prosthesis for the treatment of pathological Widenings A or defects.

Ein Ausführungsbeispiel der Erfindung ist in der Zeichnung dargestellt.An embodiment of the invention is in the drawing shown.

Claims (2)

1. Stütze (Stent) für kanalikuläre Körperstrukturen (z. B. Blutgefäße, Gallengänge, Speise- und Luftröhre), dadurch gekennzeichnet, daß die Stütze aus einer durchgehenden, röhrenförmigen, selbständig erweiternden, flexiblen Gitterstruktur besteht1. support (stent) for canalicular body structures (z. B. blood vessels, bile ducts, esophagus and trachea), characterized in that the support consists of a continuous, tubular, independently expanding, flexible lattice structure 2. Stütze nach Patentanspruch 1, dadurch gekennzeichnet, daß die röhrenförmige Stütze aus einer wabenartigen Gitterstruktur besteht aus einem Stück, ohne scharfkantige Lücken mit sinuswellenartigen Längskomponenten, die an den Berührungspunkten nicht durchgehend sondern unterschiedlich versetzt, seitlich verbunden sind, so daß die Möglichkeit longitudinaler und querer Verbiegung besteht2. support according to claim 1, characterized, that the tubular support from a honeycomb Grid structure consists of one piece, without sharp-edged Gaps with sine wave-like longitudinal components connected to the Points of contact are not continuous but different offset, laterally connected, so that the possibility there is longitudinal and transverse bending
DE1995112066 1995-04-01 1995-04-01 Stent for transluminal implantation e.g. blood vessels Ceased DE19512066A1 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
DE1995112066 DE19512066A1 (en) 1995-04-01 1995-04-01 Stent for transluminal implantation e.g. blood vessels
DE1995116191 DE19516191A1 (en) 1995-04-01 1995-05-07 Support (stent, prosthesis) for canalicular body structures, e.g. Blood vessels, bile ducts, esophagus and trachea
ES96104982T ES2119527T5 (en) 1995-04-01 1996-03-28 STENT DEVICE FOR TRANSLUMINAL IMPLEMENTATION IN HOLLOW ORGANS.
DE59600411T DE59600411D1 (en) 1995-04-01 1996-03-28 Stent for transluminal implantation in hollow organs
EP96104982A EP0734698B9 (en) 1995-04-01 1996-03-28 Stent for transluminal implantation into hollow organs
DK96104982T DK0734698T4 (en) 1995-04-01 1996-03-28 Stent for transluminal implantation in hollow organs
AT96104982T ATE169484T1 (en) 1995-04-01 1996-03-28 STENT FOR TRANSLUMINAL IMPLANTATION IN HOLLOW ORGANS
US08/624,294 US5876449A (en) 1995-04-01 1996-03-29 Stent for the transluminal implantation in hollow organs
JP11288496A JP3168531B2 (en) 1995-04-01 1996-04-01 Stent for transluminal insertion into hollow organs

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1995112066 DE19512066A1 (en) 1995-04-01 1995-04-01 Stent for transluminal implantation e.g. blood vessels

Publications (1)

Publication Number Publication Date
DE19512066A1 true DE19512066A1 (en) 1996-11-28

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Family Applications (2)

Application Number Title Priority Date Filing Date
DE1995112066 Ceased DE19512066A1 (en) 1995-04-01 1995-04-01 Stent for transluminal implantation e.g. blood vessels
DE1995116191 Ceased DE19516191A1 (en) 1995-04-01 1995-05-07 Support (stent, prosthesis) for canalicular body structures, e.g. Blood vessels, bile ducts, esophagus and trachea

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE1995116191 Ceased DE19516191A1 (en) 1995-04-01 1995-05-07 Support (stent, prosthesis) for canalicular body structures, e.g. Blood vessels, bile ducts, esophagus and trachea

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DE (2) DE19512066A1 (en)

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19634245A1 (en) * 1996-08-25 1998-02-26 Joerg Meyer Expandable stent and method for its manufacture
EP1129673A3 (en) * 2000-03-01 2001-12-12 Medinol Ltd. Longitudinally flexible stent
US6723119B2 (en) 2000-03-01 2004-04-20 Medinol Ltd. Longitudinally flexible stent
US7141062B1 (en) 2000-03-01 2006-11-28 Medinol, Ltd. Longitudinally flexible stent
US7621947B2 (en) 2000-03-01 2009-11-24 Medinol, Ltd. Longitudinally flexible stent
US7758627B2 (en) 2000-03-01 2010-07-20 Medinol, Ltd. Longitudinally flexible stent
US7763064B2 (en) 2004-06-08 2010-07-27 Medinol, Ltd. Stent having struts with reverse direction curvature
US7828835B2 (en) 2000-03-01 2010-11-09 Medinol Ltd. Longitudinally flexible stent
US8202312B2 (en) 2000-03-01 2012-06-19 Medinol Ltd. Longitudinally flexible stent
US8382821B2 (en) 1998-12-03 2013-02-26 Medinol Ltd. Helical hybrid stent
US8496699B2 (en) 2000-03-01 2013-07-30 Medinol Ltd. Longitudinally flexible stent
US9039755B2 (en) 2003-06-27 2015-05-26 Medinol Ltd. Helical hybrid stent
US9155639B2 (en) 2009-04-22 2015-10-13 Medinol Ltd. Helical hybrid stent
US9161849B1 (en) 2000-03-01 2015-10-20 Medinol Ltd. Longitudinally flexible stent

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10044043A1 (en) * 2000-08-30 2002-03-14 Biotronik Mess & Therapieg Repositionable stent

Cited By (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19634245A1 (en) * 1996-08-25 1998-02-26 Joerg Meyer Expandable stent and method for its manufacture
US8382821B2 (en) 1998-12-03 2013-02-26 Medinol Ltd. Helical hybrid stent
US7828835B2 (en) 2000-03-01 2010-11-09 Medinol Ltd. Longitudinally flexible stent
US8202312B2 (en) 2000-03-01 2012-06-19 Medinol Ltd. Longitudinally flexible stent
US6723119B2 (en) 2000-03-01 2004-04-20 Medinol Ltd. Longitudinally flexible stent
US7141062B1 (en) 2000-03-01 2006-11-28 Medinol, Ltd. Longitudinally flexible stent
US7621947B2 (en) 2000-03-01 2009-11-24 Medinol, Ltd. Longitudinally flexible stent
US7722658B2 (en) 2000-03-01 2010-05-25 Medinol Ltd. Longitudinally flexible stent
US7758627B2 (en) 2000-03-01 2010-07-20 Medinol, Ltd. Longitudinally flexible stent
US9968471B1 (en) 2000-03-01 2018-05-15 Medinol Ltd. Longitudinally flexible stent
EP1295573A3 (en) * 2000-03-01 2003-06-04 Medinol Ltd. Longitudinally flexible stent
US6709453B2 (en) 2000-03-01 2004-03-23 Medinol Ltd. Longitudinally flexible stent
US8317851B2 (en) 2000-03-01 2012-11-27 Medinol Ltd. Longitudinally flexible stent
EP1129673A3 (en) * 2000-03-01 2001-12-12 Medinol Ltd. Longitudinally flexible stent
US8496699B2 (en) 2000-03-01 2013-07-30 Medinol Ltd. Longitudinally flexible stent
US9161849B1 (en) 2000-03-01 2015-10-20 Medinol Ltd. Longitudinally flexible stent
US9039755B2 (en) 2003-06-27 2015-05-26 Medinol Ltd. Helical hybrid stent
US9456910B2 (en) 2003-06-27 2016-10-04 Medinol Ltd. Helical hybrid stent
US10363152B2 (en) 2003-06-27 2019-07-30 Medinol Ltd. Helical hybrid stent
US7763064B2 (en) 2004-06-08 2010-07-27 Medinol, Ltd. Stent having struts with reverse direction curvature
US9155639B2 (en) 2009-04-22 2015-10-13 Medinol Ltd. Helical hybrid stent

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