DE122007000064I2 - Erythropoietinkonjugate - Google Patents

Erythropoietinkonjugate

Info

Publication number
DE122007000064I2
DE122007000064I2 DE122007000064C DE122007000064C DE122007000064I2 DE 122007000064 I2 DE122007000064 I2 DE 122007000064I2 DE 122007000064 C DE122007000064 C DE 122007000064C DE 122007000064 C DE122007000064 C DE 122007000064C DE 122007000064 I2 DE122007000064 I2 DE 122007000064I2
Authority
DE
Germany
Prior art keywords
erythropoietinkonjugate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE122007000064C
Other languages
English (en)
Other versions
DE122007000064I1 (de
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27495518&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE122007000064(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE122007000064I1 publication Critical patent/DE122007000064I1/de
Publication of DE122007000064I2 publication Critical patent/DE122007000064I2/de
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • C07K17/08—Peptides being immobilised on, or in, an organic carrier the carrier being a synthetic polymer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]
DE122007000064C 1999-07-02 2000-06-28 Erythropoietinkonjugate Active DE122007000064I2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US14225499P 1999-07-02 1999-07-02
US15022599P 1999-08-23 1999-08-23
US15154899P 1999-08-31 1999-08-31
US16615199P 1999-11-17 1999-11-17

Publications (2)

Publication Number Publication Date
DE122007000064I1 DE122007000064I1 (de) 2008-01-03
DE122007000064I2 true DE122007000064I2 (de) 2010-03-25

Family

ID=27495518

Family Applications (3)

Application Number Title Priority Date Filing Date
DE60036053T Expired - Lifetime DE60036053T2 (de) 1999-07-02 2000-06-28 Erythropoietinkonjugate
DE122007000064C Active DE122007000064I2 (de) 1999-07-02 2000-06-28 Erythropoietinkonjugate
DE10031839A Ceased DE10031839A1 (de) 1999-07-02 2000-06-30 Erythropoietinkonjugate

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE60036053T Expired - Lifetime DE60036053T2 (de) 1999-07-02 2000-06-28 Erythropoietinkonjugate

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE10031839A Ceased DE10031839A1 (de) 1999-07-02 2000-06-30 Erythropoietinkonjugate

Country Status (52)

Country Link
US (2) US6583272B1 (de)
EP (2) EP1064951B1 (de)
JP (2) JP3727009B2 (de)
KR (1) KR100593143B1 (de)
CN (2) CN1283664C (de)
AR (2) AR024625A1 (de)
AT (1) ATE370748T1 (de)
AU (1) AU736067B2 (de)
BG (1) BG65449B1 (de)
BR (2) BR0002276A (de)
CA (1) CA2310536C (de)
CO (1) CO5190661A1 (de)
CY (2) CY1107719T1 (de)
CZ (1) CZ299516B6 (de)
DE (3) DE60036053T2 (de)
DK (1) DK1064951T3 (de)
DO (1) DOP2000000030A (de)
EA (1) EA003777B1 (de)
ES (2) ES2289985T3 (de)
FR (2) FR2795734B1 (de)
GB (2) GB2393960C (de)
GC (1) GC0000197A (de)
GE (1) GEP20022804B (de)
GT (1) GT200000109A (de)
HK (2) HK1068354A1 (de)
HR (1) HRP20000436B1 (de)
HU (1) HU226233B1 (de)
ID (1) ID26447A (de)
IL (1) IL137056A0 (de)
IS (1) IS2492B (de)
IT (1) IT1318606B1 (de)
LU (1) LU91363I2 (de)
MA (1) MA26746A1 (de)
MX (1) MXPA00006547A (de)
MY (1) MY128500A (de)
NL (1) NL300289I9 (de)
NO (2) NO327043B1 (de)
NZ (1) NZ505454A (de)
OA (1) OA11442A (de)
PA (1) PA8497801A1 (de)
PE (1) PE20010297A1 (de)
PL (1) PL202758B1 (de)
PT (1) PT1064951E (de)
RS (1) RS49928B (de)
SG (1) SG92717A1 (de)
SI (1) SI1064951T1 (de)
SK (1) SK286301B6 (de)
SV (1) SV2002000120A (de)
TN (1) TNSN00147A1 (de)
TR (1) TR200001956A2 (de)
TW (1) TWI235667B (de)
UY (1) UY26228A1 (de)

Families Citing this family (224)

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US20030105294A1 (en) * 1998-02-25 2003-06-05 Stephen Gillies Enhancing the circulating half life of antibody-based fusion proteins
JP2002511432A (ja) * 1998-04-15 2002-04-16 レキシジェン ファーマシューティカルズ コーポレイション 新脈管形成インヒビターの同時投与による抗体−サイトカイン融合タンパク質媒介性免疫応答の増強
US7304150B1 (en) 1998-10-23 2007-12-04 Amgen Inc. Methods and compositions for the prevention and treatment of anemia
US7345019B1 (en) * 1999-04-13 2008-03-18 The Kenneth S. Warren Institute, Inc. Modulation of excitable tissue function by peripherally administered erythropoietin
CZ299516B6 (cs) * 1999-07-02 2008-08-20 F. Hoffmann-La Roche Ag Konjugát erythropoetinového glykoproteinu, zpusobjeho výroby a použití a farmaceutická kompozice sjeho obsahem
SK782002A3 (en) 1999-07-21 2003-08-05 Lexigen Pharm Corp FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens
US7067110B1 (en) 1999-07-21 2006-06-27 Emd Lexigen Research Center Corp. Fc fusion proteins for enhancing the immunogenicity of protein and peptide antigens
MXPA02001417A (es) * 1999-08-09 2002-08-12 Lexigen Pharm Corp Complejos multiples de citosina-anticuerpo.
US20050202538A1 (en) * 1999-11-12 2005-09-15 Merck Patent Gmbh Fc-erythropoietin fusion protein with improved pharmacokinetics
AU4314801A (en) * 2000-02-11 2001-08-20 Lexigen Pharm Corp Enhancing the circulating half-life of antibody-based fusion proteins
US6586398B1 (en) * 2000-04-07 2003-07-01 Amgen, Inc. Chemically modified novel erythropoietin stimulating protein compositions and methods
DK1311285T4 (en) † 2000-05-15 2017-07-24 Hoffmann La Roche Liquid pharmaceutical composition containing an erythropoietin derivative
CN1270775C (zh) * 2000-06-29 2006-08-23 默克专利有限公司 通过与免疫细胞因子摄入促进剂联合治疗来增强抗体－细胞因子融合蛋白介导的免疫反应
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CN1280137A (zh) 2001-01-17
JP3727009B2 (ja) 2005-12-14
LU91363I9 (de) 2018-12-31
BG65449B1 (bg) 2008-08-29
GT200000109A (es) 2001-12-21
DOP2000000030A (es) 2002-07-15
ES2191511A1 (es) 2003-09-01
BG104570A (en) 2001-09-28
KR20010049676A (ko) 2001-06-15
KR100593143B1 (ko) 2006-06-26
MA26746A1 (fr) 2004-12-20
FR2795734B1 (fr) 2005-09-30
HU226233B1 (en) 2008-07-28
CA2310536C (en) 2007-09-11
HUP0002553A3 (en) 2005-11-28
IL137056A0 (en) 2001-06-14
GB0400086D0 (en) 2004-02-04
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AU4274400A (en) 2001-01-04
LU91363I2 (fr) 2007-11-12
HUP0002553A2 (en) 2001-03-28
EA003777B1 (ru) 2003-08-28
SI1064951T1 (sl) 2007-12-31
CN1283664C (zh) 2006-11-08
FR2795734A1 (fr) 2001-01-05
DE60036053T2 (de) 2008-01-03
NL300289I9 (nl) 2019-08-21
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CN1515590A (zh) 2004-07-28
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EA200000607A1 (ru) 2001-02-26
OA11442A (fr) 2004-04-28
PT1064951E (pt) 2007-09-10
SV2002000120A (es) 2002-01-31
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ATE370748T1 (de) 2007-09-15
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PE20010297A1 (es) 2001-03-07
NO2009010I2 (no) 2014-06-02
EP1064951A3 (de) 2002-03-20
ID26447A (id) 2001-01-04
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ITMI20001479A1 (it) 2001-12-30
GC0000197A (en) 2006-03-29
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TR200001956A2 (tr) 2001-01-22
DE122007000064I1 (de) 2008-01-03
NO20003372D0 (no) 2000-06-28
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TWI235667B (en) 2005-07-11
EP1064951A2 (de) 2001-01-03
BRPI0002276B8 (pt) 2021-05-25
IS5554A (is) 2001-01-02
US6583272B1 (en) 2003-06-24
IT1318606B1 (it) 2003-08-27
HU0002553D0 (en) 2000-08-28
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AU736067B2 (en) 2001-07-26
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YU40700A (sh) 2003-12-31
NL300289I2 (nl) 2010-02-01

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