CA2693296C
(en)
*
|
1997-12-08 |
2013-09-10 |
Merck Patent Gmbh |
Heterodimeric fusion proteins useful for targeted immune therapy and general immune stimulation
|
US20030105294A1
(en)
*
|
1998-02-25 |
2003-06-05 |
Stephen Gillies |
Enhancing the circulating half life of antibody-based fusion proteins
|
ATE329622T1
(de)
*
|
1998-04-15 |
2006-07-15 |
Lexigen Pharm Corp |
Steigerung der antikörper-zytokin- fusionsproteinmediierten immunantwort durch mitverabreichung mit einem angiogeneseinhibitor
|
US7304150B1
(en)
*
|
1998-10-23 |
2007-12-04 |
Amgen Inc. |
Methods and compositions for the prevention and treatment of anemia
|
US7345019B1
(en)
*
|
1999-04-13 |
2008-03-18 |
The Kenneth S. Warren Institute, Inc. |
Modulation of excitable tissue function by peripherally administered erythropoietin
|
CZ299516B6
(cs)
*
|
1999-07-02 |
2008-08-20 |
F. Hoffmann-La Roche Ag |
Konjugát erythropoetinového glykoproteinu, zpusobjeho výroby a použití a farmaceutická kompozice sjeho obsahem
|
US7067110B1
(en)
|
1999-07-21 |
2006-06-27 |
Emd Lexigen Research Center Corp. |
Fc fusion proteins for enhancing the immunogenicity of protein and peptide antigens
|
SK782002A3
(en)
|
1999-07-21 |
2003-08-05 |
Lexigen Pharm Corp |
FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens
|
RU2263118C2
(ru)
*
|
1999-08-09 |
2005-10-27 |
Лексиген Фармасьютикэлс Корп. |
Комплексы антител с несколькими цитокинами
|
US20050202538A1
(en)
*
|
1999-11-12 |
2005-09-15 |
Merck Patent Gmbh |
Fc-erythropoietin fusion protein with improved pharmacokinetics
|
JP5179689B2
(ja)
*
|
2000-02-11 |
2013-04-10 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
抗体ベース融合タンパク質の循環系内半減期の増強
|
US6586398B1
(en)
*
|
2000-04-07 |
2003-07-01 |
Amgen, Inc. |
Chemically modified novel erythropoietin stimulating protein compositions and methods
|
RU2281116C2
(ru)
†
|
2000-05-15 |
2006-08-10 |
Ф.Хоффманн-Ля Рош Аг |
Новая фармацевтическая композиция
|
DK1294401T3
(da)
*
|
2000-06-29 |
2007-10-08 |
Merck Patent Gmbh |
Forbedring af antistof/cytokin-fusionsproteinmedierede immunresponser ved kombineret behandling med immuncytokin-optagelsesforberende midler
|
EP1333036B1
(de)
*
|
2000-10-16 |
2009-01-21 |
Chugai Seiyaku Kabushiki Kaisha |
Peg-modifiziertes erythropoietin
|
BR0116381A
(pt)
*
|
2000-12-20 |
2004-02-25 |
Hoffmann La Roche |
Conjugado, composição farmacêutica que compreende o mesmo e sua utilização, processo para o tratamento profilático e/ou terapêutico de distúrbios, processo para a preparação de um conjugado, compostos e glicoproteìnas de eritropoetina
|
DE60144439D1
(de)
*
|
2000-12-20 |
2011-05-26 |
Hoffmann La Roche |
Konjugate von erythropoietin (epo) mit polyethylenglykol (peg)
|
US7767643B2
(en)
|
2000-12-29 |
2010-08-03 |
The Kenneth S. Warren Institute, Inc. |
Protection, restoration, and enhancement of erythropoietin-responsive cells, tissues and organs
|
US20030072737A1
(en)
*
|
2000-12-29 |
2003-04-17 |
Michael Brines |
Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs
|
EP1234583A1
(de)
*
|
2001-02-23 |
2002-08-28 |
F. Hoffmann-La Roche Ag |
PEG-Konjugate des HGF-NK4
|
CA2440221C
(en)
*
|
2001-03-07 |
2013-02-05 |
Merck Patent Gesellschaft Mit Beschraenkter Haftung |
Expression technology for proteins containing a hybrid isotype antibody moiety
|
DE10112825A1
(de)
|
2001-03-16 |
2002-10-02 |
Fresenius Kabi De Gmbh |
HESylierung von Wirkstoffen in wässriger Lösung
|
WO2002079415A2
(en)
*
|
2001-03-30 |
2002-10-10 |
Lexigen Pharmaceuticals Corp. |
Reducing the immunogenicity of fusion proteins
|
PL205352B1
(pl)
*
|
2001-05-03 |
2010-04-30 |
Merck Patent Gmbh |
Rekombinowane przeciwciało specyficzne dla nowotworu
|
US6818613B2
(en)
|
2001-11-07 |
2004-11-16 |
Ortho-Mcneil Pharmaceutical, Inc. |
Aqueous sustained-release formulations of proteins
|
KR100467751B1
(ko)
|
2001-12-03 |
2005-01-24 |
씨제이 주식회사 |
생체내 에리스로포이에틴 활성이 증진된 융합단백질
|
EP1454138B1
(de)
*
|
2001-12-04 |
2012-01-18 |
Merck Patent GmbH |
Immunocytokine mit modulierter selektivität
|
WO2003053997A2
(en)
*
|
2001-12-06 |
2003-07-03 |
Fibrogen, Inc. |
Methods of increasing endogenous erythropoietin (epo)
|
DE10209821A1
(de)
|
2002-03-06 |
2003-09-25 |
Biotechnologie Ges Mittelhesse |
Kopplung von Proteinen an ein modifiziertes Polysaccharid
|
DE10209822A1
(de)
|
2002-03-06 |
2003-09-25 |
Biotechnologie Ges Mittelhesse |
Kopplung niedermolekularer Substanzen an ein modifiziertes Polysaccharid
|
US7129267B2
(en)
|
2002-03-11 |
2006-10-31 |
Janssen Pharmaceutica N.V. |
Methods for SHP1 mediated neuroprotection
|
PL374580A1
(en)
*
|
2002-07-01 |
2005-10-31 |
The Kenneth S.Warren Institute, Inc. |
Recombinant tissue protective cytokines and encoding nucleic acids thereof for protection, restoration, and enhancement of responsive cells, tissues, and organs
|
AU2003258518B2
(en)
|
2002-07-24 |
2007-01-18 |
F. Hoffmann-La Roche Ag |
Polyalkylene glycol acid additives
|
US7459435B2
(en)
*
|
2002-08-29 |
2008-12-02 |
Hoffmann-La Roche Inc. |
Treatment of disturbances of iron distribution
|
WO2004022593A2
(en)
*
|
2002-09-09 |
2004-03-18 |
Nautilus Biotech |
Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules
|
US20050176627A1
(en)
*
|
2002-09-09 |
2005-08-11 |
Anthony Cerami |
Long acting erythropoietins that maintain tissue protective activity of endogenous erythropoietin
|
PL217085B1
(pl)
*
|
2002-09-11 |
2014-06-30 |
Fresenius Kabi Gmbh |
Koniugat hydroksyalkiloskrobi i polipeptydu, sposób wytwarzania koniugatu hydroksyalkiloskrobi i polipeptydu, zastosowanie koniugatu hydroksyalkiloskrobi i polipeptydu oraz kompozycja farmaceutyczna koniugatu hydroksyalkiloskrobi i polipeptydu
|
US7459436B2
(en)
*
|
2002-11-22 |
2008-12-02 |
Hoffmann-La Roche Inc. |
Treatment of disturbances of iron distribution
|
US7388079B2
(en)
*
|
2002-11-27 |
2008-06-17 |
The Regents Of The University Of California |
Delivery of pharmaceutical agents via the human insulin receptor
|
RU2366664C2
(ru)
*
|
2002-12-17 |
2009-09-10 |
Мерк Патент Гмбх |
Гуманизированное антитело (н14.18) на основании антитела 14.18 мыши, связывающееся с gd2, и его слияние с il-2
|
US7553930B2
(en)
|
2003-01-06 |
2009-06-30 |
Xencor, Inc. |
BAFF variants and methods thereof
|
US20060104968A1
(en)
|
2003-03-05 |
2006-05-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
|
US7642340B2
(en)
|
2003-03-31 |
2010-01-05 |
Xencor, Inc. |
PEGylated TNF-α variant proteins
|
US7610156B2
(en)
|
2003-03-31 |
2009-10-27 |
Xencor, Inc. |
Methods for rational pegylation of proteins
|
CA2520875A1
(en)
|
2003-03-31 |
2004-10-21 |
Xencor, Inc. |
Methods for rational pegylation of proteins
|
US7279174B2
(en)
*
|
2003-05-08 |
2007-10-09 |
Advanced Cardiovascular Systems, Inc. |
Stent coatings comprising hydrophilic additives
|
US7919118B2
(en)
*
|
2003-05-12 |
2011-04-05 |
Affymax, Inc. |
Spacer moiety for poly (ethylene glycol) modified peptide based compounds
|
ES2395413T3
(es)
*
|
2003-05-12 |
2013-02-12 |
Affymax, Inc. |
Péptidos que se unen al receptor de eritropoyetina
|
SI1629007T1
(sl)
|
2003-05-12 |
2009-10-31 |
Affymax Inc |
Novi peptidi, ki se veĹľejo na eritropoetinski receptor
|
EP2336162A1
(de)
*
|
2003-05-12 |
2011-06-22 |
Affymax, Inc. |
Neue polyethylenglycol-modifizierte Agoniste von Erythropoietin und deren Verwendungen
|
CA2527665A1
(en)
*
|
2003-05-30 |
2004-12-16 |
Centocor, Inc. |
Formation of novel erythropoietin conjugates using transglutaminase
|
US7662607B2
(en)
*
|
2003-07-30 |
2010-02-16 |
New Century Pharmaceuticals, Inc. |
Chalaropsis lysozyme protein and its method of use in anti-bacterial applications
|
WO2005014655A2
(en)
|
2003-08-08 |
2005-02-17 |
Fresenius Kabi Deutschland Gmbh |
Conjugates of hydroxyalkyl starch and a protein
|
JP2007517769A
(ja)
*
|
2003-09-29 |
2007-07-05 |
ウォーレン ファーマシューティカルズ,インコーポレーテッド |
敗血症および癒着形成の治療および予防のための組織保護性サイトカイン
|
EP1675871A2
(de)
|
2003-10-10 |
2006-07-05 |
Xencor Inc. |
Tnf-alpha-varianten auf proteinbasis zur behandlung von erkrankungen in verbindung mit tnf-alpha
|
WO2005058347A1
(en)
*
|
2003-12-19 |
2005-06-30 |
F. Hoffmann-La Roche Ag |
Use of erythropoietin in the treatment of disturbances of iron distribution in chronic inflammatory intestinal diseases
|
EP1548031A1
(de)
*
|
2003-12-22 |
2005-06-29 |
Dubai Genetics FZ-LLC |
Naturidentischer Erythropoietin
|
KR20060124656A
(ko)
*
|
2003-12-31 |
2006-12-05 |
메르크 파텐트 게엠베하 |
개선된 약물동태를 가지는 Fc-에리스로포이에틴 융합단백질
|
EP1756173B1
(de)
*
|
2004-01-21 |
2019-04-03 |
Nektar Therapeutics |
Verfahren zur herstellung von propionsäureterminierten polymeren
|
CN1914223B
(zh)
*
|
2004-02-02 |
2012-02-29 |
Ambrx公司 |
经修饰的人类四螺旋束多肽及其用途
|
CA2558738C
(en)
|
2004-03-11 |
2013-02-05 |
Fresenius Kabi Deutschland Gmbh |
Conjugates of hydroxyalkyl starch and a protein, prepared by reductive amination
|
US7588745B2
(en)
*
|
2004-04-13 |
2009-09-15 |
Si Options, Llc |
Silicon-containing products
|
US7253650B2
(en)
|
2004-05-25 |
2007-08-07 |
International Business Machines Corporation |
Increase productivity at wafer test using probe retest data analysis
|
WO2006062685A2
(en)
*
|
2004-11-11 |
2006-06-15 |
Affymax, Inc. |
Novel peptides that bind to the erythropoietin receptor
|
CN101142234A
(zh)
*
|
2004-11-11 |
2008-03-12 |
阿费麦克斯公司 |
结合红细胞生成素受体的新肽
|
JP5735194B2
(ja)
|
2005-01-25 |
2015-06-17 |
セル セラピューティクス インコーポレーテッド |
改善された生体内半減期を有する生物学的に活性なタンパク質
|
EP1848461A2
(de)
*
|
2005-02-16 |
2007-10-31 |
Nektar Therapeutics Al, Corporation |
Konjugate einer epo-gruppierung und eines polymers
|
US7550433B2
(en)
*
|
2005-06-03 |
2009-06-23 |
Affymax, Inc. |
Erythropoietin receptor peptide formulations and uses
|
US7919461B2
(en)
|
2005-06-03 |
2011-04-05 |
Affymax, Inc. |
Erythropoietin receptor peptide formulations and uses
|
US8324159B2
(en)
*
|
2005-06-03 |
2012-12-04 |
Affymax, Inc. |
Erythropoietin receptor peptide formulations and uses
|
US20070072795A1
(en)
*
|
2005-09-28 |
2007-03-29 |
Anton Haselbeck |
Treatment of neurodegenerative disorders
|
WO2007041713A1
(en)
*
|
2005-10-04 |
2007-04-12 |
Zymogenetics, Inc. |
Production and purification of il-29
|
US8124095B2
(en)
*
|
2005-10-07 |
2012-02-28 |
Armagen Technologies, Inc. |
Fusion proteins for delivery of erythropoietin to the CNS
|
US8142781B2
(en)
*
|
2005-10-07 |
2012-03-27 |
Armagen Technologies, Inc. |
Fusion proteins for blood-brain barrier delivery
|
US8741260B2
(en)
*
|
2005-10-07 |
2014-06-03 |
Armagen Technologies, Inc. |
Fusion proteins for delivery of GDNF to the CNS
|
CN101291684A
(zh)
*
|
2005-10-21 |
2008-10-22 |
阿维季尼克斯股份有限公司 |
甘醇化和糖基化的禽类来源的治疗性蛋白
|
US20080171696A1
(en)
*
|
2005-10-21 |
2008-07-17 |
Avigenics, Inc. |
Pharmacodynamically enhanced therapeutic proteins
|
US20130172274A1
(en)
*
|
2005-12-20 |
2013-07-04 |
Duke University |
Methods and compositions for delivering active agents with enhanced pharmacological properties
|
US8841255B2
(en)
|
2005-12-20 |
2014-09-23 |
Duke University |
Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides
|
US20100166700A1
(en)
*
|
2006-02-28 |
2010-07-01 |
Oligasis Corporation |
Acryloyloxyethylphosphorylcholine Containing Polymer Conjugates and Their Preparation
|
EP1997505A4
(de)
|
2006-03-22 |
2013-02-13 |
Chugai Pharmaceutical Co Ltd |
Zubereitung einer erythropoetinlösung
|
JP5723528B2
(ja)
*
|
2006-08-04 |
2015-05-27 |
プロロング ファーマシューティカルズ エルエルシー |
修飾されたエリスロポエチン
|
US7741446B2
(en)
*
|
2006-08-18 |
2010-06-22 |
Armagen Technologies, Inc. |
Fusion antibodies that cross the blood-brain barrier in both directions
|
EP2120998B1
(de)
*
|
2006-11-28 |
2013-08-07 |
HanAll Biopharma Co., Ltd. |
Modifizierte erythropoetin-polypeptide und ihre verwendungen zur behandlung
|
AR065083A1
(es)
*
|
2007-02-02 |
2009-05-13 |
Amgen Inc |
Hepcidina, antagonistas de la hepcidina y metodos de uso
|
WO2008137066A1
(en)
*
|
2007-05-02 |
2008-11-13 |
The Board Of Regents Of The University Of Oklahoma |
Use of compacted nucleic acid nanoparticles in non-viral treatments of ocular diseases
|
AR067537A1
(es)
*
|
2007-07-17 |
2009-10-14 |
Hoffmann La Roche |
Purificacion de polipeptidos pegilados
|
AR067536A1
(es)
*
|
2007-07-17 |
2009-10-14 |
Hoffmann La Roche |
Metodo para obtener una eritropoyetina mono-pegilada en una forma sustancialmente homogenea
|
CA3184105A1
(en)
*
|
2007-07-27 |
2009-02-05 |
Armagen Inc. |
Methods and compositions for increasing alpha-l-iduronidase activity in the cns
|
US8383114B2
(en)
*
|
2007-09-27 |
2013-02-26 |
Amgen Inc. |
Pharmaceutical formulations
|
EP3381445B1
(de)
|
2007-11-15 |
2023-10-25 |
Amgen Inc. |
Wässrige antikörperformulierung mit stabilisierung durch antioxidantien zur parenteralen verabreichung
|
US8101706B2
(en)
|
2008-01-11 |
2012-01-24 |
Serina Therapeutics, Inc. |
Multifunctional forms of polyoxazoline copolymers and drug compositions comprising the same
|
EP3042922B1
(de)
|
2008-01-11 |
2017-07-19 |
Serina Therapeutics, Inc. |
Multifunktionelle formen von polyoxazolincopolymeren und wirkstoffzusammensetzungen damit
|
ES2500066T3
(es)
|
2008-01-25 |
2014-09-30 |
Amgen, Inc |
Anticuerpos frente a ferroportina y métodos de uso
|
CN101939443B
(zh)
|
2008-02-08 |
2014-01-29 |
Ambrx公司 |
经修饰瘦素多肽和其用途
|
TWI395593B
(zh)
|
2008-03-06 |
2013-05-11 |
Halozyme Inc |
可活化的基質降解酵素之活體內暫時性控制
|
KR20100135291A
(ko)
|
2008-04-14 |
2010-12-24 |
할로자임, 아이엔씨 |
히알루로난 관련 질환 및 상태 치료용 변형된 히알루로니다제 및 그 용도
|
CA2722600C
(en)
|
2008-05-01 |
2014-01-21 |
Amgen Inc. |
Anti-hepcidin antibodies and methods of use
|
CA2726894A1
(en)
|
2008-06-27 |
2009-12-30 |
Duke University |
Therapeutic agents comprising elastin-like peptides
|
BRPI0919403A2
(pt)
|
2008-09-26 |
2017-09-26 |
Ambrx Inc |
polipeptídeos modificados de eritropoetina animal e seus usos
|
CN104922669A
(zh)
|
2008-11-13 |
2015-09-23 |
通用医疗公司 |
用于通过调整bmp-6来调节铁稳态的方法和组合物
|
PT3037529T
(pt)
|
2008-12-09 |
2019-05-31 |
Halozyme Inc |
Polipéptidos ph20 estendidos solúveis e suas utilizações
|
US9533055B2
(en)
|
2009-03-18 |
2017-01-03 |
Armagen Technologies, Inc. |
Compositions and methods for blood-brain barrier delivery of IgG-decoy receptor fusion proteins
|
MX2012000735A
(es)
|
2009-07-30 |
2012-01-27 |
Hoffmann La Roche |
Separador de columna de cromatografia movible.
|
WO2011024025A1
(en)
*
|
2009-08-28 |
2011-03-03 |
Avesthagen Limited |
An erythropoietin analogue and a method thereof
|
WO2011034604A2
(en)
|
2009-09-17 |
2011-03-24 |
Baxter Healthcare, S.A. |
Stable co-formulation of hyaluronidase and immunoglobulin, and methods of use thereof
|
US20120264688A1
(en)
*
|
2009-09-23 |
2012-10-18 |
Walter Hinderer |
Process for the purification of recombinant human erythropoietin (epo), epo thus purified and pharmaceutical compositions comprising same
|
SI2485761T1
(sl)
|
2009-10-09 |
2019-05-31 |
Armagen, Inc. |
Postopki in sestavki za povečanje aktivnosti iduronat-2-sulfataze v CŽS
|
US9662271B2
(en)
|
2009-10-23 |
2017-05-30 |
Amgen Inc. |
Vial adapter and system
|
WO2011075185A1
(en)
|
2009-12-18 |
2011-06-23 |
Oligasis |
Targeted drug phosphorylcholine polymer conjugates
|
RU2588658C2
(ru)
|
2010-04-27 |
2016-07-10 |
ЭсСиАйЭл Текнолоджи ГмбХ |
Стабильные водные композиции белка mia/cd-rap
|
EA024052B1
(ru)
|
2010-06-07 |
2016-08-31 |
Эмджен Инк. |
Устройство для доставки лекарственного средства
|
MX348420B
(es)
|
2010-07-20 |
2017-06-12 |
Halozyme Inc |
Efectos secundarios adversos asociados con la administracion de agentes anti-hialuronano y metodos para mejorar o prevenir los efectos secundarios.
|
JP5735650B2
(ja)
|
2010-09-14 |
2015-06-17 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
Peg化エリスロポエチンを精製するための方法
|
WO2012104278A1
(en)
|
2011-02-02 |
2012-08-09 |
F. Hoffmann-La Roche Ag |
Chromatography column support
|
EP2672958A1
(de)
|
2011-02-08 |
2013-12-18 |
Halozyme, Inc. |
Zusammensetzung und lipidformulierung eines hyaluronan-abbauenden enzym und seine verwendung zur behandlung von benigner prostatahyperplasie
|
US9480624B2
(en)
|
2011-03-31 |
2016-11-01 |
Amgen Inc. |
Vial adapter and system
|
JP6038884B2
(ja)
|
2011-04-20 |
2016-12-07 |
アムゲン・インコーポレーテッド |
自動式注射装置
|
US20130011378A1
(en)
|
2011-06-17 |
2013-01-10 |
Tzung-Horng Yang |
Stable formulations of a hyaluronan-degrading enzyme
|
DK3045189T3
(en)
|
2011-10-14 |
2018-06-18 |
Amgen Inc |
Injector and mounting method
|
SG11201401797TA
(en)
|
2011-10-24 |
2014-09-26 |
Halozyme Inc |
Companion diagnostic for anti-hyaluronan agent therapy and methods of use thereof
|
AU2012346448B2
(en)
|
2011-12-02 |
2017-09-14 |
Armagen, Inc. |
Methods and compositions for increasing arylsulfatase A activity in the CNS
|
LT3130347T
(lt)
|
2011-12-30 |
2019-10-25 |
Halozyme Inc |
Ph20 polipeptido variantai, kompozicijos ir jų panaudojimas
|
JP6042527B2
(ja)
|
2012-04-04 |
2016-12-14 |
ハロザイム インコーポレイテッド |
抗ヒアルロナン剤と腫瘍標的タキサンの組み合わせ治療
|
CN102816227A
(zh)
*
|
2012-08-30 |
2012-12-12 |
深圳赛保尔生物药业有限公司 |
回收促红细胞生成素的方法
|
US9278124B2
(en)
|
2012-10-16 |
2016-03-08 |
Halozyme, Inc. |
Hypoxia and hyaluronan and markers thereof for diagnosis and monitoring of diseases and conditions and related methods
|
EP4234694A3
(de)
|
2012-11-21 |
2023-09-06 |
Amgen Inc. |
Arzneimittelabgabevorrichtung
|
US10492990B2
(en)
|
2013-03-15 |
2019-12-03 |
Amgen Inc. |
Drug cassette, autoinjector, and autoinjector system
|
NZ631098A
(en)
|
2013-03-15 |
2016-09-30 |
Intrinsic Lifesciences Llc |
Anti-hepcidin antibodies and uses thereof
|
TWI580451B
(zh)
|
2013-03-15 |
2017-05-01 |
安美基公司 |
用於注射器之匣盒及使用具有自動注射器及匣盒之自動注射器設備之方法
|
AU2014238267B2
(en)
|
2013-03-22 |
2019-08-15 |
Amgen Inc. |
Injector and method of assembly
|
TW201534726A
(zh)
|
2013-07-03 |
2015-09-16 |
Halozyme Inc |
熱穩定ph20玻尿酸酶變異體及其用途
|
US10702608B2
(en)
|
2013-09-08 |
2020-07-07 |
Kodiak Sciences Inc. |
Factor VIII zwitterionic polymer conjugates
|
MX2016005315A
(es)
|
2013-10-24 |
2016-08-11 |
Amgen Inc |
Sistema de administracion de farmacos con control sensible a la temperatura.
|
MX2016005312A
(es)
|
2013-10-24 |
2016-08-11 |
Amgen Inc |
Inyector y metodo de montaje.
|
US10994112B2
(en)
|
2014-02-05 |
2021-05-04 |
Amgen Inc. |
Drug delivery system with electromagnetic field generator
|
WO2015171777A1
(en)
|
2014-05-07 |
2015-11-12 |
Amgen Inc. |
Autoinjector with shock reducing elements
|
JP6817074B2
(ja)
|
2014-06-03 |
2021-01-20 |
アムジエン・インコーポレーテツド |
制御可能な薬物送達システム及び使用方法
|
US9840553B2
(en)
|
2014-06-28 |
2017-12-12 |
Kodiak Sciences Inc. |
Dual PDGF/VEGF antagonists
|
PL3186281T3
(pl)
|
2014-08-28 |
2019-10-31 |
Halozyme Inc |
Terapia skojarzona enzymem rozkładającym hialuronian i inhibitorem punktu kontrolnego odpowiedzi immunologicznej
|
WO2016049036A1
(en)
|
2014-09-22 |
2016-03-31 |
Intrinsic Lifesciences Llc |
Humanized anti-hepcidin antibodies and uses thereof
|
US10695506B2
(en)
|
2014-10-14 |
2020-06-30 |
Amgen Inc. |
Drug injection device with visual and audio indicators
|
EA201700181A1
(ru)
|
2014-10-14 |
2017-09-29 |
Галозим, Инк. |
Композиции аденозиндеаминазы-2 (ада-2), их варианты и способы использования
|
KR20210013299A
(ko)
|
2014-10-17 |
2021-02-03 |
코디악 사이언시스 인코포레이티드 |
부티릴콜린에스테라제 양성이온성 중합체 컨쥬게이트
|
ES2898469T3
(es)
|
2014-12-19 |
2022-03-07 |
Amgen Inc |
Dispositivo de administración de medicamentos con sensor de proximidad
|
ES2785311T3
(es)
|
2014-12-19 |
2020-10-06 |
Amgen Inc |
Dispositivo de administración de fármacos con botón móvil o campo de interfaz de usuario
|
US10538589B2
(en)
|
2015-01-14 |
2020-01-21 |
Armagen Inc. |
Methods and compositions for increasing N-acetylglucosaminidase (NAGLU) activity in the CNS using a fusion antibody comprising an anti-human insulin receptor antibody and NAGLU
|
JP6484345B2
(ja)
|
2015-02-17 |
2019-03-20 |
アムジエン・インコーポレーテツド |
固定及び/または戻りが真空によって支援された薬物送達装置
|
US11806509B2
(en)
|
2015-02-27 |
2023-11-07 |
Amgen Inc. |
Drug delivery device having a needle guard mechanism with a turnable threshold of resistance to needle guard movement
|
WO2017039786A1
(en)
|
2015-09-02 |
2017-03-09 |
Amgen Inc. |
Syringe assembly adapter for a syringe
|
US11351308B2
(en)
|
2015-12-09 |
2022-06-07 |
Amgen Inc. |
Auto-injector with signaling cap
|
BR112018013407A2
(pt)
|
2015-12-30 |
2018-12-18 |
Kodiak Sciences Inc |
anticorpos e conjugados dos mesmos
|
US11154661B2
(en)
|
2016-01-06 |
2021-10-26 |
Amgen Inc. |
Auto-injector with signaling electronics
|
EP4035711A1
(de)
|
2016-03-15 |
2022-08-03 |
Amgen Inc. |
Verringerung der wahrscheinlichkeit auf glasbruch in arzneimittelabgabevorrichtungen
|
CN105820232B
(zh)
*
|
2016-04-08 |
2019-05-17 |
昂德生物药业有限公司 |
单修饰聚乙二醇重组人促红素的制备方法及其制品和应用
|
US11541168B2
(en)
|
2016-04-29 |
2023-01-03 |
Amgen Inc. |
Drug delivery device with messaging label
|
US11389588B2
(en)
|
2016-05-02 |
2022-07-19 |
Amgen Inc. |
Syringe adapter and guide for filling an on-body injector
|
CA3018426A1
(en)
|
2016-05-13 |
2017-11-16 |
Amgen Inc. |
Vial sleeve assembly
|
EP3458988B1
(de)
|
2016-05-16 |
2023-10-18 |
Amgen Inc. |
Datenverschlüsselung in medizinischen vorrichtungen mit eingeschränkter rechenfähigkeit
|
EP3465124A1
(de)
|
2016-06-03 |
2019-04-10 |
Amgen Inc. |
Wirkungstestvorrichtungen und verfahren für wirkstofffreisetzungsvorrichtungen
|
WO2018004842A1
(en)
|
2016-07-01 |
2018-01-04 |
Amgen Inc. |
Drug delivery device having minimized risk of component fracture upon impact events
|
CA3027143A1
(en)
|
2016-07-15 |
2018-01-18 |
F. Hoffmann-La Roche Ag |
Method for purifying pegylated erythropoietin
|
WO2018034784A1
(en)
|
2016-08-17 |
2018-02-22 |
Amgen Inc. |
Drug delivery device with placement detection
|
WO2018081234A1
(en)
|
2016-10-25 |
2018-05-03 |
Amgen Inc. |
On-body injector
|
AU2018210301A1
(en)
|
2017-01-17 |
2019-08-01 |
Amgen Inc. |
Injection devices and related methods of use and assembly
|
MX2019009625A
(es)
|
2017-02-17 |
2019-10-09 |
Amgen Inc |
Dispositivo de administracion de farmacos con trayectoria de flujo de fluido esteril y metodo relacionado de ensamblaje.
|
US11369736B2
(en)
|
2017-02-17 |
2022-06-28 |
Amgen Inc. |
Cannula insertion and retraction mechanisms
|
MX2019010544A
(es)
|
2017-03-06 |
2019-10-21 |
Amgen Inc |
Dispositivo de administracion de farmacos con caracteristica de prevencion de la activacion.
|
JP2020509839A
(ja)
|
2017-03-07 |
2020-04-02 |
アムジエン・インコーポレーテツド |
超過圧力による針の挿入
|
JP2020509837A
(ja)
|
2017-03-09 |
2020-04-02 |
アムジエン・インコーポレーテツド |
薬剤送達装置のための挿入機構
|
EP3570871B1
(de)
|
2017-03-20 |
2020-11-18 |
H. Hoffnabb-La Roche Ag |
Verfahren für in-vitro-glyco-engineering eines erythropoiesestimulierenden proteins
|
US11957883B2
(en)
|
2017-03-28 |
2024-04-16 |
Amgen Inc. |
Plunger rod and syringe assembly system and method
|
EP3634546A1
(de)
|
2017-06-08 |
2020-04-15 |
Amgen Inc. |
Drehmomentangetriebene arzneimittelabgabevorrichtung
|
CA3061982A1
(en)
|
2017-06-08 |
2018-12-13 |
Amgen Inc. |
Syringe assembly for a drug delivery device and method of assembly
|
JP7195276B2
(ja)
|
2017-06-22 |
2022-12-23 |
アムジエン・インコーポレーテツド |
デバイス起動による衝突/衝撃の低減
|
SG10202110492YA
(en)
|
2017-06-22 |
2021-11-29 |
Catalyst Biosciences Inc |
Modified membrane type serine protease 1 (mtsp-1) polypeptides and methods of use
|
EP3641861A1
(de)
|
2017-06-23 |
2020-04-29 |
Amgen Inc. |
Elektronische arzneimittelabgabevorrichtung mit einer durch eine schaltungsanordnung aktivierten kappe
|
JP7408398B2
(ja)
|
2017-07-14 |
2024-01-05 |
アムジエン・インコーポレーテツド |
二重ねじりばねシステムを有する針挿入後退システム
|
WO2019018169A1
(en)
|
2017-07-21 |
2019-01-24 |
Amgen Inc. |
PERMEABLE GAS SEALING ELEMENT FOR MEDICINE CONTAINER AND METHODS OF ASSEMBLY
|
US11617837B2
(en)
|
2017-07-25 |
2023-04-04 |
Amgen Inc. |
Drug delivery device with gear module and related method of assembly
|
JP7242562B2
(ja)
|
2017-07-25 |
2023-03-20 |
アムジエン・インコーポレーテツド |
容器アクセスシステムを有する薬物送達デバイス及び関連する組立方法
|
US20200164155A1
(en)
|
2017-08-09 |
2020-05-28 |
Amgen Inc. |
Hydraulic-pneumatic pressurized chamber drug delivery system
|
MA49897A
(fr)
|
2017-08-18 |
2020-06-24 |
Amgen Inc |
Injecteur sur-corps avec patch adhésif stérile
|
US11103636B2
(en)
|
2017-08-22 |
2021-08-31 |
Amgen Inc. |
Needle insertion mechanism for drug delivery device
|
MA50611A
(fr)
|
2017-10-04 |
2020-08-12 |
Amgen Inc |
Adaptateur d'écoulement destiné à un dispositif d'administration de médicament
|
EP3691716B1
(de)
|
2017-10-06 |
2023-11-29 |
Amgen Inc. |
Arzneimittelabgabevorrichtung mit verriegelungsvorrichtung und zugehöriges montageverfahren
|
US11464903B2
(en)
|
2017-10-09 |
2022-10-11 |
Amgen Inc. |
Drug delivery device with drive assembly and related method of assembly
|
EP3703779A1
(de)
|
2017-11-03 |
2020-09-09 |
Amgen Inc. |
Systeme und ansätze zur sterilisation einer arzneimittelabgabevorrichtung
|
EP3707075A1
(de)
|
2017-11-06 |
2020-09-16 |
Amgen Inc. |
Füllabschlussanordnungen und zugehörige verfahren
|
US20200261648A1
(en)
|
2017-11-06 |
2020-08-20 |
Amgen Inc. |
Drug delivery device with placement and flow sensing
|
MA50557A
(fr)
|
2017-11-10 |
2020-09-16 |
Amgen Inc |
Pistons pour dispositifs d'administration de médicament
|
WO2019099324A1
(en)
|
2017-11-16 |
2019-05-23 |
Amgen Inc. |
Door latch mechanism for drug delivery device
|
WO2019099322A1
(en)
|
2017-11-16 |
2019-05-23 |
Amgen Inc. |
Autoinjector with stall and end point detection
|
SG11202005990RA
(en)
|
2017-12-29 |
2020-07-29 |
Hoffmann La Roche |
Process for providing pegylated protein composition
|
PL3731873T3
(pl)
|
2017-12-29 |
2022-04-25 |
F. Hoffmann-La Roche Ag |
Sposób dostarczania kompozycji pegylowanego białka
|
CN111801120A
(zh)
|
2017-12-29 |
2020-10-20 |
豪夫迈·罗氏有限公司 |
用于提供聚乙二醇化蛋白质组合物的方法
|
US20190351031A1
(en)
|
2018-05-16 |
2019-11-21 |
Halozyme, Inc. |
Methods of selecting subjects for combination cancer therapy with a polymer-conjugated soluble ph20
|
US10835685B2
(en)
|
2018-05-30 |
2020-11-17 |
Amgen Inc. |
Thermal spring release mechanism for a drug delivery device
|
US11083840B2
(en)
|
2018-06-01 |
2021-08-10 |
Amgen Inc. |
Modular fluid path assemblies for drug delivery devices
|
WO2020023336A1
(en)
|
2018-07-24 |
2020-01-30 |
Amgen Inc. |
Hybrid drug delivery devices with grip portion
|
CN112469454B
(zh)
|
2018-07-24 |
2024-01-26 |
安进公司 |
用于施用药物的输送装置
|
US20210260279A1
(en)
|
2018-07-24 |
2021-08-26 |
Amgen Inc. |
Hybrid drug delivery devices with optional grip portion and related method of preparation
|
CA3103682A1
(en)
|
2018-07-24 |
2020-01-30 |
Amgen Inc. |
Delivery devices for administering drugs
|
MA53320A
(fr)
|
2018-07-31 |
2021-11-03 |
Amgen Inc |
Ensemble de trajet de fluide pour dispositif d'administration de médicament
|
DK3613486T3
(da)
*
|
2018-08-24 |
2021-01-04 |
Uga Biopharma Gmbh |
Metode og anlæg til rengøring af epo og/eller et epo-derivat
|
JP2022500095A
(ja)
|
2018-09-24 |
2022-01-04 |
アムジエン・インコーポレーテツド |
インターベンション投薬システム及び方法
|
EP3856283A1
(de)
|
2018-09-28 |
2021-08-04 |
Amgen Inc. |
Anordnung zur aktivierung des muskeldrahtvorschubs für eine medikamentenabgabevorrichtung
|
WO2020072577A1
(en)
|
2018-10-02 |
2020-04-09 |
Amgen Inc. |
Injection systems for drug delivery with internal force transmission
|
EP3860686A1
(de)
|
2018-10-05 |
2021-08-11 |
Amgen Inc. |
Medikamentenabgabevorrichtung mit dosisindikator
|
AU2019361919A1
(en)
|
2018-10-15 |
2021-03-18 |
Amgen Inc. |
Drug delivery device having damping mechanism
|
EP3866889A1
(de)
|
2018-10-15 |
2021-08-25 |
Amgen Inc. |
Plattformmontageverfahren für medikamentenabgabevorrichtung
|
MA54057A
(fr)
|
2018-11-01 |
2022-02-09 |
Amgen Inc |
Dispositifs d'administration de médicament à rétraction partielle d'élément d'administration de médicament
|
WO2020092056A1
(en)
|
2018-11-01 |
2020-05-07 |
Amgen Inc. |
Drug delivery devices with partial needle retraction
|
EP3873566A1
(de)
|
2018-11-01 |
2021-09-08 |
Amgen Inc. |
Vorrichtung zur verabreichung von medikamenten mit teilweisem rückzug des medikamentenabgabeelements
|
US11613744B2
(en)
|
2018-12-28 |
2023-03-28 |
Vertex Pharmaceuticals Incorporated |
Modified urokinase-type plasminogen activator polypeptides and methods of use
|
MX2021012557A
(es)
|
2019-04-24 |
2021-11-12 |
Amgen Inc |
Conjuntos y metodos de verificacion de esterilizacion de jeringuillas.
|
AU2020337250A1
(en)
|
2019-08-23 |
2022-03-03 |
Amgen Inc. |
Drug delivery device with configurable needle shield engagement components and related methods
|
CA3157509A1
(en)
|
2019-10-10 |
2021-04-15 |
Kodiak Sciences Inc. |
Methods of treating an eye disorder
|
WO2022063082A1
(zh)
|
2020-09-22 |
2022-03-31 |
美国杰科实验室有限公司 |
一种糖基化修饰的促红细胞生成素及其应用
|
WO2022159414A1
(en)
|
2021-01-22 |
2022-07-28 |
University Of Rochester |
Erythropoietin for gastroinfestinal dysfunction
|
JPWO2022239704A1
(de)
|
2021-05-10 |
2022-11-17 |
|
|
WO2022246055A1
(en)
|
2021-05-21 |
2022-11-24 |
Amgen Inc. |
Method of optimizing a filling recipe for a drug container
|
WO2023209074A1
(en)
|
2022-04-28 |
2023-11-02 |
Institut National de la Santé et de la Recherche Médicale |
Methods of restoring erythropoiesis in patients suffering from a sf3b1 mutant myelodysplastic syndrome by correcting coasy mis-splicing
|
CN116492448A
(zh)
*
|
2023-04-12 |
2023-07-28 |
深圳赛保尔生物药业有限公司 |
负载peg-epo及间充质干细胞的组合物、药物及其制备方法
|