DE122006000061I2 - Kontrastmittel fur diagnostische bildgebung mit verlangerter verweilzeit im blut. - Google Patents

Kontrastmittel fur diagnostische bildgebung mit verlangerter verweilzeit im blut.

Info

Publication number
DE122006000061I2
DE122006000061I2 DE200612000061 DE122006000061C DE122006000061I2 DE 122006000061 I2 DE122006000061 I2 DE 122006000061I2 DE 200612000061 DE200612000061 DE 200612000061 DE 122006000061 C DE122006000061 C DE 122006000061C DE 122006000061 I2 DE122006000061 I2 DE 122006000061I2
Authority
DE
Germany
Prior art keywords
blood
retention time
contrast agent
diagnostic imaging
prolonged retention
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE200612000061
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Epix Pharmaceuticals Inc
Original Assignee
Epix Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epix Pharmaceuticals Inc filed Critical Epix Pharmaceuticals Inc
Publication of DE122006000061I2 publication Critical patent/DE122006000061I2/de
Active legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0002General or multifunctional contrast agents, e.g. chelated agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • A61K49/101Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/103Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • A61K49/101Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/106Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/091Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/50Clinical applications
    • A61B6/507Clinical applications involving determination of haemodynamic parameters, e.g. perfusion CT

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
DE200612000061 1995-02-01 2006-11-10 Kontrastmittel fur diagnostische bildgebung mit verlangerter verweilzeit im blut. Active DE122006000061I2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38231795A 1995-02-01 1995-02-01
PCT/US1996/000164 WO1996023526A2 (en) 1995-02-01 1996-01-16 Diagnostic imaging contrast agents with extended blood retention

Publications (1)

Publication Number Publication Date
DE122006000061I2 true DE122006000061I2 (de) 2012-06-21

Family

ID=23508434

Family Applications (3)

Application Number Title Priority Date Filing Date
DE69636635T Expired - Lifetime DE69636635T2 (de) 1995-02-01 1996-01-16 Kontrastmittel für diagnostische bildgebung mit verlängerter verweilzeit im blut
DE1996636635 Pending DE122006000061I1 (de) 1995-02-01 1996-01-16 Kontrastmittel f}r Diagnostische Bildgebung mit Verl{ngerter Verweilzeit im Blut
DE200612000061 Active DE122006000061I2 (de) 1995-02-01 2006-11-10 Kontrastmittel fur diagnostische bildgebung mit verlangerter verweilzeit im blut.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DE69636635T Expired - Lifetime DE69636635T2 (de) 1995-02-01 1996-01-16 Kontrastmittel für diagnostische bildgebung mit verlängerter verweilzeit im blut
DE1996636635 Pending DE122006000061I1 (de) 1995-02-01 1996-01-16 Kontrastmittel f}r Diagnostische Bildgebung mit Verl{ngerter Verweilzeit im Blut

Country Status (25)

Country Link
US (8) US6676929B2 (de)
EP (2) EP1716871A3 (de)
JP (4) JP4064458B2 (de)
KR (1) KR100403755B1 (de)
CN (3) CN100361711C (de)
AR (1) AR006510A1 (de)
AT (1) ATE342738T1 (de)
AU (1) AU689700B2 (de)
BR (1) BR9607136A (de)
CA (1) CA2211100C (de)
DE (3) DE69636635T2 (de)
DK (1) DK0806968T3 (de)
ES (1) ES2274523T3 (de)
FI (1) FI973183A (de)
HK (2) HK1002551A1 (de)
IL (1) IL116847A (de)
IS (1) IS2505B (de)
MY (1) MY128089A (de)
NL (1) NL300253I2 (de)
NO (2) NO326114B1 (de)
NZ (1) NZ301181A (de)
PT (1) PT806968E (de)
TW (1) TW319763B (de)
WO (1) WO1996023526A2 (de)
ZA (1) ZA96417B (de)

Families Citing this family (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW319763B (de) * 1995-02-01 1997-11-11 Epix Medical Inc
US6770261B2 (en) 1995-06-02 2004-08-03 Research Corporation Technologies Magnetic resonance imaging agents for the detection of physiological agents
US6713045B1 (en) 1995-06-02 2004-03-30 Research Corporation Technologies, Inc. Targeted magnetic resonance imaging agents for the detection of physiological processes
DE19543077C2 (de) * 1995-11-13 1997-10-16 Schering Ag Verwendung von gashaltigen Metallkomplexen als Ultraschallkontrastmittel
NZ331629A (en) * 1996-04-01 2000-04-28 Epix Medical Inc Bioactivated diagnostic imaging contrast agents
US5900228A (en) 1996-07-31 1999-05-04 California Institute Of Technology Bifunctional detection agents having a polymer covalently linked to an MRI agent and an optical dye
US5919967A (en) * 1997-04-11 1999-07-06 Epix Medical, Inc. Process for synthesizing phosphodiesters
DE19744004C1 (de) * 1997-09-26 1999-07-22 Schering Ag Lipophile Metall-Komplexe für Nekrose und Infarkt-Imaging
US6495118B1 (en) 1997-09-26 2002-12-17 Schering Aktiengesellschaft Lipophilic metal complexes for necrosis and infarction imaging
IL134985A0 (en) * 1997-10-02 2001-05-20 Epix Medical Inc A method for contrast enhanced diagnostic imaging
JP2001521011A (ja) * 1997-10-27 2001-11-06 カリフォルニア・インスティテュート・オブ・テクノロジー 治療成分送達のための磁気共鳴イメージング剤
US6713046B1 (en) 1997-10-27 2004-03-30 Research Corporation Technologies Magnetic resonance imaging agents for the delivery of therapeutic agents
AU752812B2 (en) 1997-11-17 2002-10-03 Research Corporation Technologies, Inc. Magnetic resonance imaging agents for the detection of physiological agents
GB9912356D0 (en) 1999-05-26 1999-07-28 Btg Int Ltd Generation of microfoam
JP3848493B2 (ja) * 1999-06-30 2006-11-22 英三 盛 X線診断システム
HUP0202635A3 (en) * 1999-07-29 2006-03-28 Epix Medical Inc Cambridge Targeting multimeric imaging agents through multilocus binding
DE19944893C2 (de) * 1999-09-09 2001-09-20 Schering Ag Calcium-Komplex von [[(4R)-4-[bis[(carboxy-.kappa.O)methyl]amino-. kappa.N]-6,9-bis[(carboxy-.kappa.O)methyl]-1-[(4,4-diphenylcyclohexyl)oxy]-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-yl-säure-.kappa.N6, .kappa.N9,.kappa.O11]1-oxidato(6-)]-, hexahydrogen, dessen Salze und diese Komplexe enthaltende pharmazeutische Mittel
US6559330B1 (en) 1999-09-09 2003-05-06 Schering Aktiengesellschaft Calcium complex of [[(4r)-4-[bis{carboxy-.kappa.o)methyl]amino-.kappa.n]-6,9-bis[(carboxy.kappa.o)methyl]-1-[(4,4-diphenylcyclohexyl)oxy]-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-ylic-acid-.kappa.n6,.kappa.n9,.kappa.011]1-oxidato(6-)]-, hexahydrogen, its salts, pharmaceutical agents that contain these complexes, their use in treatment and as additives in diagnosis, as well as processes for the production of the complexes and agents
DK1072604T3 (da) * 1999-09-09 2001-06-25 Schering Ag Calciumkompleks af 4R0-4-bis(carboxy-kappa.O)methyl-amino-.kappa.N-6,9-bis(carboxy-.kappa.O)methyl-1-(4,4-diphenylcyclohexyl)oxy-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-yl-syre-.kappa.N6,.kappa.N9,.kappa.o11-1-oxidato(6-)-, hexa........
DE19964224B4 (de) * 1999-09-09 2005-09-01 Schering Ag Pharmazeutische Mittel enthaltend Calcium-Komplex von [[(4R)-4-[bis[(carboxy-.kappa.O)methyl]amino-.kappa.N]-6,9-bis[(carboxy-.kappa.O)methyl]-1-[(4,4-diphenylcyclohexyl)oxy]-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-yl-säure-.kappa.N6,.kappa.N9,.kappa.011]1-oxidato(6-)]-, tetrahydrogen (MS-325) und dessen Salze sowie Verfahren zur Herstellung der Mittel
US20030203879A1 (en) * 1999-09-09 2003-10-30 Schering Ag Calcium complex of [[(4R)-4-[bis[(carboxy-.kappa.O)methyl]amino-.kappa.n]-6,9-bis[(carboxy.kappa.O)methyl]-1-[(4,4-diphenylcyclohexy)oxy]-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-ylic-acid-.kappa.N6,.Kappa.N9,.Kappa 011]1-oxidato(6-)]-, hexahydrogen, its salts, pharmaceutical agents that contain these complexes, their use in treatment and as additives in diagnosis, as well as processes for the production of the complexes and agents
AU1791501A (en) 1999-11-22 2001-06-04 Epix Medical, Inc. Imaging sexual response
US20030082106A1 (en) * 2000-01-22 2003-05-01 Aleksandr Nivorozhkin Magnetic resonance imaging using contrast agents bioactivated by enzymatic cleavage
US6673333B1 (en) 2000-05-04 2004-01-06 Research Corporation Technologies, Inc. Functional MRI agents for cancer imaging
AU2001276956A1 (en) 2000-07-17 2002-01-30 California Institute Of Technology Macrocyclic mri contrast agents
AU2002211517A1 (en) 2000-10-04 2002-04-15 California Institute Of Technology Magnetic resonance imaging agents for in vivo labeling and detection of amyloid deposits
US6549798B2 (en) 2001-02-07 2003-04-15 Epix Medical, Inc. Magnetic resonance angiography data
TWI221406B (en) 2001-07-30 2004-10-01 Epix Medical Inc Systems and methods for targeted magnetic resonance imaging of the vascular system
TWI284539B (en) 2001-07-30 2007-08-01 Epix Pharm Inc A method for making a magnetic resonance (MR) imaging agent, a MR imaging contrast agent, a method for altering stability of a peptide and a modified peptide
US8512680B2 (en) 2001-08-08 2013-08-20 Btg International Ltd. Injectables in foam, new pharmaceutical applications
WO2003013573A1 (en) * 2001-08-10 2003-02-20 Epix Medical, Inc. Polypeptide conjugates with extended circulating half-lives
WO2003029257A1 (de) * 2001-09-27 2003-04-10 Schering Aktiengesellschaft (ethylen)-(propylen/butylen)-phosphodiester-triaminpentaessigsäure-derivate
US7261876B2 (en) 2002-03-01 2007-08-28 Bracco International Bv Multivalent constructs for therapeutic and diagnostic applications
CA2513044A1 (en) 2002-03-01 2004-08-05 Dyax Corp. Kdr and vegf/kdr binding peptides and their use in diagnosis and therapy
ES2506142T3 (es) 2002-03-01 2014-10-13 Dyax Corp. Péptidos de unión a KDR y a VEGF/KDR y su uso en diagnóstico
US8623822B2 (en) 2002-03-01 2014-01-07 Bracco Suisse Sa KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
US7794693B2 (en) 2002-03-01 2010-09-14 Bracco International B.V. Targeting vector-phospholipid conjugates
US7226577B2 (en) 2003-01-13 2007-06-05 Bracco Imaging, S. P. A. Gastrin releasing peptide compounds
PT2949658T (pt) 2003-03-03 2018-10-18 Bracco Suisse Sa Péptidos que ligam especificamente o recetor de hgf (cmet) e utilizações dos mesmos
BRPI0410635A (pt) 2003-05-23 2006-06-13 Epix Pharm Inc isÈmeros enriquecidos e opticamente puros de ligantes de quelação e agentes de contraste
US7251520B2 (en) * 2003-07-08 2007-07-31 General Electric Company Method and apparatus of slice selective magnetization preparation for moving table MRI
AR047692A1 (es) * 2003-07-10 2006-02-08 Epix Medical Inc Imagenes de blancos estacionarios
US8048439B2 (en) 2003-11-17 2011-11-01 Btg International Ltd. Therapeutic foam
EP1701701B2 (de) 2003-11-17 2018-11-28 BTG International Limited Verfahren zur herstellung eines schaums mit einem sklerosierenden mittel
DE102004026102B4 (de) * 2004-05-25 2006-08-24 Schering Ag Verfahren zur Herstellung von 1-Hydroxymethyl-1,3,5-triazapentan, Trihydrochlorid
US7189879B2 (en) 2004-05-25 2007-03-13 Schering Ag Process for the production of 1-hydroxymethyl-1,3,5-triazapentane, trihydrochloride
EP1768558A4 (de) * 2004-06-09 2009-11-25 Kereos Inc Lipophile derivate von chelat-monoamiden
DE102004062258B3 (de) * 2004-12-23 2006-01-05 Schering Ag Hydroxypyridinon-Derivate, deren Metallkomplexe und deren Verwendung zur Herstellung von Konjugaten mit Biomolekülen
US8613904B2 (en) 2005-01-26 2013-12-24 The Regents Of The University Of Colorado Methods for diagnosis and intervention of hepatic disorders
US8778299B2 (en) * 2005-01-26 2014-07-15 The Regents Of The University Of Colorado, A Body Corporate Methods for diagnosis and intervention of hepatic disorders
MX2007009354A (es) * 2005-02-03 2008-01-14 Epix Pharm Inc Metodos de perfusion en estado estable.
JP2006248978A (ja) 2005-03-10 2006-09-21 Mebiopharm Co Ltd 新規なリポソーム製剤
GB0509824D0 (en) 2005-05-13 2005-06-22 Btg Int Ltd Therapeutic foam
WO2007002109A2 (en) * 2005-06-20 2007-01-04 The Regents Of The University Of California Multidentate pyrone-derived chelators for medicinal imaging and chelation
KR100762359B1 (ko) * 2005-06-28 2007-10-05 원광대학교산학협력단 신생혈관특이적 엠알 조영제 및 이의 제조방법
KR100762357B1 (ko) * 2005-06-28 2007-10-05 원광대학교산학협력단 염증특이적 엠알 조영제 및 이의 제조방법
EP1901659B1 (de) 2005-07-13 2018-04-25 Georgia State University Research Foundation, Inc. Kontrastmittel und verfahren zur herstellung von kontrastmitteln
JP5377965B2 (ja) 2005-09-09 2013-12-25 ジョージア ステート ユニバーシティ リサーチ ファウンデーション、インコーポレイテッド 標的化された造影剤および造影剤を標的化するための方法
WO2007073792A1 (de) * 2005-12-19 2007-07-05 Bayer Schering Pharma Aktiengesellschaft Verfahren zur herstellung von 4,4-diphenylcyclohexanol
WO2007084264A2 (en) 2005-12-29 2007-07-26 Epix Pharmaceuticals, Inc. Methods for myocardial imaging
DE102006025940B4 (de) * 2006-06-02 2009-11-05 Siemens Ag Dielektrisches Element, Verfahren zur Erzeugung von Magnetresonanzaufnahmen eines Untersuchungsobjekts und Verwendung des dielektrischen Elements
WO2008019123A2 (en) 2006-08-04 2008-02-14 Georgia State University Research Foundation, Inc. Enzyme sensors, methods for preparing and using such sensors, and methods of detecting protease activity
CA2660717A1 (en) * 2006-08-17 2008-02-21 Epix Pharmaceuticals, Inc. Methods for lymph system imaging
EP2097507B1 (de) 2006-12-14 2015-05-06 Georgia State University Research Foundation, Inc. Analytsensoren und verwendung davon für den nachweis von analytaktivität
DE102007002726A1 (de) * 2007-01-18 2008-07-31 Bayer Schering Pharma Aktiengesellschaft Neue Kaskaden-Polymer-Komplexe, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel
JPWO2008108163A1 (ja) * 2007-03-06 2010-06-10 コニカミノルタホールディングス株式会社 ガドリニウム化合物及びmri用造影剤
EP1982733A1 (de) * 2007-04-17 2008-10-22 Bayer Schering Pharma Aktiengesellschaft Verwendung eines Kontrastmittels zur Bildgebung durch magnetische Resonanz eines Endolecks
WO2008144728A1 (en) * 2007-05-21 2008-11-27 Bracco Imaging S.P.A. Conjugates which bind a blood protein such as human serum albumin and methods of using the same in diagnostic and therapeutic applications
JP5730581B2 (ja) 2008-01-08 2015-06-10 ランセウス メディカル イメージング, インコーポレイテッド 造影剤としてのn−アルコキシアミド抱合体
EP2257316B1 (de) 2008-04-02 2018-11-07 Georgia State University Research Foundation, Inc. Kontrastmittel, verfahren zur herstellung von kontrastmitteln und abbildungsverfahren
US20120045393A1 (en) 2009-03-17 2012-02-23 Linder Karen E Lhrh-ii peptide analogs
WO2010121133A2 (en) 2009-04-17 2010-10-21 The General Hospital Corporation Multimodal imaging of fibrin
JP2012521352A (ja) 2009-03-19 2012-09-13 ワイス・エルエルシー [2−(8,9−ジオキソ−2,6−ジアザビシクロ[5.2.0]ノナ−1(7)−エン−2−イル)エチル]ホスホン酸およびその前駆体を調製するための方法
EP2451776B1 (de) 2009-07-08 2019-09-18 Lantheus Medical Imaging, Inc. N-alkoxyamidkonjugate als bildgebungsmittel
US20110071403A1 (en) * 2009-09-21 2011-03-24 Board Of Regents Of The University Of Texas System Functional near-infrared fluorescence lymphatic mapping for diagnosing, accessing, monitoring and directing therapy of lymphatic disorders
WO2011041470A2 (en) 2009-09-30 2011-04-07 Mallinckrodt Inc. Sustained-release opiate and opiate derivative compositions
WO2011046007A1 (ja) 2009-10-15 2011-04-21 国立大学法人徳島大学 ジエチレントリアミン五酢酸誘導体の製造方法およびジエチレントリアミン五酢酸誘導体
EP2432191A1 (de) * 2010-09-15 2012-03-21 Alcatel Lucent Verfahren und Systeme zur Bereitstellung eines Dienstes
CA2837598C (en) 2011-05-31 2021-06-01 The Regents Of The University Of Colorado, A Body Corporate Method for assessment of hepatic function and portal blood flow
US9952300B2 (en) 2012-03-05 2018-04-24 Bracco Imaging S.P.A. Dynamic contrast enhanced MRI method and agents for the assessment of the macromolecular transport within pathologic tissues
CA3191764A1 (en) 2012-11-12 2014-05-15 The Regents Of The University Of Colorado, A Body Corporate Disease severity index for assessment of chronic liver disease and method for diagnosis of three distinct subtypes of primary sclerosing cholangitis
TW201514188A (zh) * 2013-03-13 2015-04-16 Lantheus Medical Imaging Inc 製備釓磷維塞三鈉單水合物之方法
WO2015038968A1 (en) 2013-09-13 2015-03-19 The General Hospital Corporation Activatable fibrin-binding probes
WO2015171543A1 (en) 2014-05-05 2015-11-12 California Institute Of Technology Mutant akt-specific capture agents, compositions, and methods of using and making
US10478120B2 (en) * 2014-05-17 2019-11-19 The Johns Hopkins University MRI-guided intraarterial catheter-based method for predicting territory of local blood brain barrier opening
US10471162B2 (en) 2014-06-20 2019-11-12 The General Hospital Corporation Collagen targeted imaging probes
CN107624115B (zh) 2015-03-16 2021-10-26 加州理工学院 肉毒神经毒素特异性捕获剂、组合物、使用方法和制造方法
WO2017004211A1 (en) 2015-06-29 2017-01-05 Collagen Medical, LLC Collagen imaging compositions
US10598671B2 (en) 2015-07-15 2020-03-24 Indi Molecular, Inc. IL-17F-specific capture agents, compositions, and methods of using and making
EP3334464B1 (de) 2015-08-13 2024-04-10 The General Hospital Corporation Mangan-basierte chelatkonjugate zur molekularen mr-bildgebung
CN109476721B (zh) 2016-04-04 2022-06-28 英蒂分子公司 Cd8-特异性捕获剂、组合物及使用和制备方法
WO2018064597A1 (en) 2016-09-29 2018-04-05 Indi Molecular, Inc. Compositions for detection, inhibition and imaging of indoleamine 2,3-dioxygenase 1 (ido1) and methods of making and using same
US11358982B2 (en) 2016-11-01 2022-06-14 Ohio State Innovation Foundation Methods for the iodination of biomolecules
US11719705B2 (en) 2017-06-15 2023-08-08 Indi Molecular, Inc. IL-17F and IL-17A-specific capture agents, compositions, and methods of using and making
WO2019027999A1 (en) * 2017-07-31 2019-02-07 Ohio State Innovation Foundation BIOMIMETIC NANOMATERIALS AND USES THEREOF
US10933146B2 (en) 2017-12-12 2021-03-02 Massachusetts Institute Of Technology Cell-permeable imaging sensors and uses thereof
TWI667996B (zh) 2018-03-23 2019-08-11 中國醫藥大學附設醫院 乳房腫瘤輔助檢測模型及乳房腫瘤輔助檢測系統
US11919972B2 (en) 2018-11-02 2024-03-05 Regeneron Pharmaceuticals, Inc. Peptide libraries with non-canonical amino acids
WO2020097531A1 (en) 2018-11-08 2020-05-14 Indi Molecular, Inc. Theranostic capture agents, compositions, and methods of using and making
US20200291391A1 (en) 2019-03-12 2020-09-17 Indi Molecular, Inc. Cross-linked epitopes and methods of use thereof
US20200371101A1 (en) 2019-05-20 2020-11-26 Indi Molecular, Inc. Compositions and methods relating to detection, inhibition, and imaging of indoleamine 2,3-dioxygenase 1 (ido1)
US11414460B2 (en) 2019-07-19 2022-08-16 Institute For Systems Biology KRAS-specific capture agents, compositions, and methods of making and using
WO2021219871A2 (en) 2020-04-30 2021-11-04 Aduro Biotech Holdings, Europe B.V. Anti-cd103 antibodies
WO2022098743A1 (en) 2020-11-03 2022-05-12 Indi Molecular, Inc. Compositions, imaging, and therapeutic methods targeting folate receptor 1 (folr1)
WO2022098745A1 (en) 2020-11-03 2022-05-12 Indi Molecular, Inc. Compositions, delivery systems, and methods useful in tumor therapy

Family Cites Families (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US488008A (en) * 1892-12-13 Method of forming dental crowns
DE450742C (de) 1924-12-04 1927-10-15 Arthur Korn Dr Verfahren zur drahtlosen UEbertragung von Bildern
US3632637A (en) 1968-02-13 1972-01-04 Arthur E Martell Hydroxyaryl-containing aminocarboxylic chelating agents
US4088747A (en) 1975-02-19 1978-05-09 Australian Atomic Energy Commission Phenolic amino-carboxylic acid radiopharmaceuticals
FR2354993A1 (fr) 1976-06-16 1978-01-13 Dabeer Procede pour la preparation de derives phenoliques d'acides hydroxyalcoyl-alcoylene-diaminoacetiques et de leurs sels
US4150047A (en) 1978-03-06 1979-04-17 Air Products And Chemicals, Inc. Process for preparing halogenated metal chelates
IN152852B (de) * 1978-08-09 1984-04-21 Gen Electric Co Ltd
US4352751A (en) 1979-09-10 1982-10-05 Analytical Radiation Corporation Species-linked diamine triacetic acids and their chelates
US4308249A (en) 1979-12-13 1981-12-29 G. D. Searle & Co. Radiopharmaceutical complexes of N-(tri-substituted alkyl)-iminodiacetic acids
US4401647A (en) 1980-03-03 1983-08-30 The Regents Of The University Of Ca Radiolabeled neoglycopeptides
US4361544A (en) 1980-03-03 1982-11-30 Goldenberg Milton David Tumor localization and therapy with labeled antibodies specific to intracellular tumor-associated markers
US4331647A (en) 1980-03-03 1982-05-25 Goldenberg Milton David Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers
US4308149A (en) 1980-07-14 1981-12-29 Nalco Chemical Company Branched/cross-linked cationic phenol-formaldehyde polymers useful in wastewater treatment
US4957939A (en) 1981-07-24 1990-09-18 Schering Aktiengesellschaft Sterile pharmaceutical compositions of gadolinium chelates useful enhancing NMR imaging
US4647447A (en) 1981-07-24 1987-03-03 Schering Aktiengesellschaft Diagnostic media
DE3129906C3 (de) 1981-07-24 1996-12-19 Schering Ag Paramagnetische Komplexsalze, deren Herstellung und Mittel zur Verwendung bei der NMR-Diagnostik
US4472509A (en) 1982-06-07 1984-09-18 Gansow Otto A Metal chelate conjugated monoclonal antibodies
NL194579C (nl) 1983-01-21 2002-08-05 Schering Ag Diagnostisch middel.
FR2550449B1 (fr) 1983-08-12 1986-01-31 Commissariat Energie Atomique Agents de relaxation specifiques d'organes ou de pathologies, utilisables pour modifier les contrastes en imagerie medicale par resonance magnetique nucleaire
US4615879A (en) 1983-11-14 1986-10-07 Vanderbilt University Particulate NMR contrast agents for gastrointestinal application
SE463651B (sv) 1983-12-21 1991-01-07 Nycomed As Diagnostikum och kontrastmedel
GB8413772D0 (en) 1984-05-30 1984-07-04 Nyegaard & Co As Chemical compounds
GB8413849D0 (en) 1984-05-31 1984-07-04 Amersham Int Plc Nmr contrast agents
CA1260827A (en) 1984-08-31 1989-09-26 Richard C. Siegel Antibody-metal ion complexes
US4687659A (en) 1984-11-13 1987-08-18 Salutar, Inc. Diamide-DTPA-paramagnetic contrast agents for MR imaging
US4859451A (en) 1984-10-04 1989-08-22 Salutar, Inc. Paramagnetic contrast agents for MR imaging
US4687658A (en) 1984-10-04 1987-08-18 Salutar, Inc. Metal chelates of diethylenetriaminepentaacetic acid partial esters for NMR imaging
US4639365A (en) 1984-10-18 1987-01-27 The Board Of Regents, The University Of Texas System Gadolinium chelates as NMR contrast agents
US4746507A (en) 1985-04-02 1988-05-24 Salutar, Inc. EDHPA based contrast agents for MR imaging, apparatus and methods
US5250285A (en) 1985-05-08 1993-10-05 The General Hospital Corporation Hydroxy-aryl metal chelates for diagnostic NMR imaging
US4899755A (en) 1985-05-08 1990-02-13 The General Hospital Corporation Hepatobiliary NMR contrast agents
US4880008A (en) 1985-05-08 1989-11-14 The General Hospital Corporation Vivo enhancement of NMR relaxivity
US5525338A (en) 1992-08-21 1996-06-11 Immunomedics, Inc. Detection and therapy of lesions with biotin/avidin conjugates
US5512332A (en) 1985-10-04 1996-04-30 Immunivest Corporation Process of making resuspendable coated magnetic particles
US5017359A (en) 1985-11-01 1991-05-21 Centre National De La Recherche Scientifique Aerosol compositions for in vivo imaging and therapy
US5223242A (en) * 1985-11-05 1993-06-29 The General Hospital Corporation Negatively charged specific affinity reagents
FI72080C (fi) 1986-01-17 1987-04-13 Erkki Tapio Tuhkanen Upphaengningsfaeste av foervaringsroer foer dokument.
DE3772785D1 (de) 1986-01-23 1991-10-17 Squibb & Sons Inc 1-substituiertes-4,7,10-triscarboxymethyl-1,4,7,10-tetraazacyclododecan und analoga.
US4885363A (en) 1987-04-24 1989-12-05 E. R. Squibb & Sons, Inc. 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs
MX174467B (es) * 1986-01-23 1994-05-17 Squibb & Sons Inc 1,4,7-triscarboximetil-1,4,7,10-tetraazaciclodo decano substituido en 1 y compuestos analogos
IT1213029B (it) 1986-01-30 1989-12-07 Bracco Ind Chimica Spa Chelati di ioni metallici paramagnetici.
US4834964A (en) 1986-03-07 1989-05-30 M.R.I., Inc. Use of charged nitroxides as NMR image enhancing agents for CSF
EP0250358A3 (de) 1986-06-20 1988-10-05 Schering Aktiengesellschaft Komplexe Verbindungen
US5314679A (en) 1986-07-03 1994-05-24 Advanced Magnetics Inc. Vascular magnetic resonance imaging agent comprising nanoparticles
AU608759B2 (en) 1986-08-04 1991-04-18 Amersham Health Salutar Inc NMR imaging with paramagnetic polyvalents metal salts of poly-(acid-alkylene-amido)-alkanes
JPS6390586A (ja) * 1986-09-29 1988-04-21 リ−・フア−マス−テイカルズ・インコ−ポレイテツド 改良された接着タブ系
US5057302A (en) 1987-02-13 1991-10-15 Abbott Laboratories Bifunctional chelating agents
DE3710730A1 (de) 1987-03-31 1988-10-20 Schering Ag Substituierte komplexbildner, komplexe und komplexsalze, verfahren zu deren herstellung und diese enthaltende pharmazeutische mittel
US5223243A (en) 1987-05-08 1993-06-29 Salutar, Inc. Dipyridoxyl phosphate chelating compound intermediates useful as NMRI contrast agents
AR246956A1 (es) 1987-05-08 1994-10-31 Salutar Inc Compuesto quelante, un intermediario para preparar el mismo, y un procedimiento para preparar una composicion de medio de contraste.
US5091169A (en) * 1987-05-08 1992-02-25 Salutar, Inc. Dipyridoxyl phosphate NMRI contrast agent compositions
US4935518A (en) 1987-05-08 1990-06-19 Salutar, Inc. Manganese(II), chelate contrast agents derived from N,N'-bis-(pyridoxal ethylene diamine-N,N')-diacetic acid and derivatives thereof
US4842845A (en) 1987-05-08 1989-06-27 Salutar, Inc. Radioactive metal chelates for dipyridoxyl phosphate
GB8719041D0 (en) 1987-08-12 1987-09-16 Parker D Conjugate compounds
GB8719042D0 (en) 1987-08-12 1987-09-16 Parker D Conjugate compounds
DE3728600A1 (de) 1987-08-27 1989-03-09 Hoechst Ag Verfahren zur markierung von substanzen mit technetium oder rhenium
US5635180A (en) 1988-02-17 1997-06-03 Neorx Corporation Alteration of pharmacokinetics of proteins by charge modification
DE3806795A1 (de) 1988-02-29 1989-09-07 Schering Ag Polymer-gebundene komplexbildner, deren komplexe und konjugate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
US5513332A (en) 1988-05-31 1996-04-30 Extended Systems, Inc. Database management coprocessor for on-the-fly providing data from disk media to all without first storing data in memory therebetween
KR0130770B1 (ko) 1988-06-24 1998-04-17 나가이 아쯔시 테이프 카트리지
WO1989012631A1 (en) 1988-06-24 1989-12-28 The Dow Chemical Company Macrocyclic bifunctional chelants, complexes thereof and their antibody conjugates
DE3825278A1 (de) * 1988-07-26 1990-02-01 Basf Lacke & Farben Verfahren zur herstellung von mehrschichtigen, schuetzenden und/oder dekorativen ueberzuegen auf substratoberflaechen
EP0436579B1 (de) 1988-09-27 1993-08-04 Nycomed Salutar, Inc. Chelat-zusammensetzung
BR8907282A (pt) 1988-12-23 1991-03-12 Dow Chemical Co Processo para preparar complexos de metal funcionalizados com isotiocianato
US5078986A (en) 1989-02-15 1992-01-07 Mallinckrodt Medical, Inc. Method for enhancing magnetic resonance imaging using an image altering agent containing an excess of chelating agent
FR2643370B1 (fr) 1989-02-22 1991-08-23 Air Liquide Derives polyazotes et leurs complexes metalliques utilisables pour la fixation de l'oxygene
US5094848A (en) 1989-06-30 1992-03-10 Neorx Corporation Cleavable diphosphate and amidated diphosphate linkers
US5695739A (en) * 1989-06-30 1997-12-09 Schering Aktiengesellschaft Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production
DE3922005A1 (de) 1989-06-30 1991-01-10 Schering Ag Derivatisierte dtpa-komplexe, diese verbindungen enthaltende pharmazeutische mittel, ihre verwendung und verfahren zu deren herstellung
WO1991003200A1 (en) * 1989-08-28 1991-03-21 The General Hospital Corporation Hydroxy-aryl metal chelates for diagnostic nmr imaging
EP0418419B1 (de) * 1989-09-22 1994-12-14 Deutsche ITT Industries GmbH Zweiphasentaktgenerator
IN172208B (de) 1990-04-02 1993-05-01 Sint Sa
GB9007431D0 (en) 1990-04-03 1990-05-30 Shell Int Research Diesel fuel additives
DE4011684A1 (de) 1990-04-06 1991-10-10 Schering Ag Dtpa-monoamide, diese verbindungen enthaltende pharmazeutische mittel, ihre verwendung und verfahren zu deren herstellung
GB2250198B (en) 1990-04-18 1994-06-22 Celltech Ltd Tetra-aza macrocycles,processes for their preparation and their use in magnetic resonance imaging
CA2039399C (en) 1990-04-25 2000-09-05 C. Allen Chang Dual functioning excipient for metal chelate contrast agents
DK0485563T3 (da) * 1990-05-30 1995-03-20 Deutsches Krebsforsch Polyethersubstituerede antitumormidler
US5487390A (en) 1990-10-05 1996-01-30 Massachusetts Institute Of Technology Gas-filled polymeric microbubbles for ultrasound imaging
DE4035760A1 (de) 1990-11-08 1992-05-14 Schering Ag Mono-n-substituierte 1,4,7,10-tetraazacyclododecan-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
TW213864B (de) 1991-08-01 1993-10-01 Squibb & Sons Inc
CA2115275A1 (en) 1991-08-09 1993-02-18 David L. White Amino acid, ester and/or catechol contrast agents for mri
US5385719A (en) * 1991-09-24 1995-01-31 Unger; Evan C. Copolymers and their use as contrast agents in magnetic resonance imaging and in other applications
JP2894879B2 (ja) * 1991-10-04 1999-05-24 日本メジフィジックス株式会社 診断用造影剤
US5407659A (en) 1991-10-22 1995-04-18 Mallinckrodt Medical, Inc. Treated calcium/oxyanion-containing particles for medical diagnostic imaging
US5464696A (en) 1992-08-13 1995-11-07 Bracco International B.V. Particles for NMR imaging
US5362478A (en) 1993-03-26 1994-11-08 Vivorx Pharmaceuticals, Inc. Magnetic resonance imaging with fluorocarbons encapsulated in a cross-linked polymeric shell
US5318769A (en) 1993-03-31 1994-06-07 Sterling Winthrop Inc. Compositions of iodophenyl esters for X-ray visualization of the gastrointestinal tract
US5365180A (en) * 1993-04-16 1994-11-15 National Semiconductor Corporation Method for measuring contact resistance
EP0703790B1 (de) 1993-06-02 2000-08-16 BRACCO S.p.A. Iodierte paramagnetische chelaten, und deren verwendung als kontrastmittel
US5358704A (en) 1993-09-30 1994-10-25 Bristol-Myers Squibb Hepatobiliary tetraazamacrocyclic magnetic resonance contrast agents
DE4341724A1 (de) 1993-12-03 1995-06-08 Schering Ag Halogenaryl-substituierte Metallkomplexe enthaltende pharmazeutische Mittel, deren Verwendung in der Diagnostik, sowie Verfahren zur Herstellung der Komplexe und Mittel
DK0661279T3 (da) * 1993-12-30 2001-07-16 Guerbet Sa Polyaminiserede ligander, metalkomplekser, fremgangsmåde til deres fremstilling og diagnostiske og terapeutiske anvendelser
NO940115D0 (no) * 1994-01-13 1994-01-13 Nycomed Imaging As Kontrastmidler for roentgen- og magnettomografisk avbildning
EP0702677A1 (de) 1994-04-08 1996-03-27 BRACCO International B.V. Aromatische amidverbindungen und seine metallchelate
GB9407435D0 (en) 1994-04-14 1994-06-08 Nycomed Salutar Inc Compounds
IT1269839B (it) 1994-05-26 1997-04-15 Bracco Spa Coniugati di acidi biliari, loro derivati con complessi metallici e relativi usi
TW319763B (de) * 1995-02-01 1997-11-11 Epix Medical Inc
IT1283650B1 (it) 1996-08-02 1998-04-23 Bracco Spa Chelati paramagnetici ad alta relassivita' in siero
US6342598B1 (en) * 1998-11-26 2002-01-29 Bracco International B.V. Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents
IT1304501B1 (it) 1998-12-23 2001-03-19 Bracco Spa Uso di derivati di acidi biliari coniugati con complessi metallicicome "blood pool agents" per l'indagine diagnostica tramite risonanza
HUP0202635A3 (en) * 1999-07-29 2006-03-28 Epix Medical Inc Cambridge Targeting multimeric imaging agents through multilocus binding
IT1313617B1 (it) * 1999-08-31 2002-09-09 Bracco Spa Processo per la preparazione di derivati degli acidi biliari.

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