DE1096902T1 - Medizinische einrichtung mit poröser oberfläche zur kontrollierten wirkstofffreigage und verfahren zu ihrer herstellung - Google Patents
Medizinische einrichtung mit poröser oberfläche zur kontrollierten wirkstofffreigage und verfahren zu ihrer herstellungInfo
- Publication number
- DE1096902T1 DE1096902T1 DE1096902T DE99932279T DE1096902T1 DE 1096902 T1 DE1096902 T1 DE 1096902T1 DE 1096902 T DE1096902 T DE 1096902T DE 99932279 T DE99932279 T DE 99932279T DE 1096902 T1 DE1096902 T1 DE 1096902T1
- Authority
- DE
- Germany
- Prior art keywords
- porous surface
- production
- medical device
- active substance
- substance release
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000013543 active substance Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 239000003814 drug Substances 0.000 abstract 3
- 229940079593 drug Drugs 0.000 abstract 3
- 238000001962 electrophoresis Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000011148 porous material Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/146—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/23—Carbohydrates
- A61L2300/236—Glycosaminoglycans, e.g. heparin, hyaluronic acid, chondroitin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/42—Anti-thrombotic agents, anticoagulants, anti-platelet agents
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/110,697 US6652581B1 (en) | 1998-07-07 | 1998-07-07 | Medical device with porous surface for controlled drug release and method of making the same |
PCT/US1999/015237 WO2000001322A1 (en) | 1998-07-07 | 1999-07-06 | Medical device with porous surface for controlled drug release and method of making the same |
Publications (1)
Publication Number | Publication Date |
---|---|
DE1096902T1 true DE1096902T1 (de) | 2002-05-23 |
Family
ID=22334400
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69938047T Expired - Lifetime DE69938047D1 (de) | 1998-07-07 | 1999-07-06 | Verfahren zur herstellung einer medizinischen einrichtung mit poröser oberfläche zur kontrollierten wirkstofffreigabe |
DE1096902T Pending DE1096902T1 (de) | 1998-07-07 | 1999-07-06 | Medizinische einrichtung mit poröser oberfläche zur kontrollierten wirkstofffreigage und verfahren zu ihrer herstellung |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69938047T Expired - Lifetime DE69938047D1 (de) | 1998-07-07 | 1999-07-06 | Verfahren zur herstellung einer medizinischen einrichtung mit poröser oberfläche zur kontrollierten wirkstofffreigabe |
Country Status (8)
Country | Link |
---|---|
US (3) | US6652581B1 (de) |
EP (1) | EP1096902B1 (de) |
JP (1) | JP2002519139A (de) |
AT (1) | ATE384502T1 (de) |
CA (1) | CA2336650C (de) |
DE (2) | DE69938047D1 (de) |
ES (1) | ES2169012T1 (de) |
WO (1) | WO2000001322A1 (de) |
Cited By (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7931683B2 (en) | 2007-07-27 | 2011-04-26 | Boston Scientific Scimed, Inc. | Articles having ceramic coated surfaces |
US7938855B2 (en) | 2007-11-02 | 2011-05-10 | Boston Scientific Scimed, Inc. | Deformable underlayer for stent |
US7942926B2 (en) | 2007-07-11 | 2011-05-17 | Boston Scientific Scimed, Inc. | Endoprosthesis coating |
US7976915B2 (en) | 2007-05-23 | 2011-07-12 | Boston Scientific Scimed, Inc. | Endoprosthesis with select ceramic morphology |
US7981150B2 (en) | 2006-11-09 | 2011-07-19 | Boston Scientific Scimed, Inc. | Endoprosthesis with coatings |
US8002823B2 (en) | 2007-07-11 | 2011-08-23 | Boston Scientific Scimed, Inc. | Endoprosthesis coating |
US8029554B2 (en) | 2007-11-02 | 2011-10-04 | Boston Scientific Scimed, Inc. | Stent with embedded material |
US8067054B2 (en) | 2007-04-05 | 2011-11-29 | Boston Scientific Scimed, Inc. | Stents with ceramic drug reservoir layer and methods of making and using the same |
US8066763B2 (en) | 1998-04-11 | 2011-11-29 | Boston Scientific Scimed, Inc. | Drug-releasing stent with ceramic-containing layer |
US8071156B2 (en) | 2009-03-04 | 2011-12-06 | Boston Scientific Scimed, Inc. | Endoprostheses |
US8070797B2 (en) | 2007-03-01 | 2011-12-06 | Boston Scientific Scimed, Inc. | Medical device with a porous surface for delivery of a therapeutic agent |
US8187620B2 (en) | 2006-03-27 | 2012-05-29 | Boston Scientific Scimed, Inc. | Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents |
US8216632B2 (en) | 2007-11-02 | 2012-07-10 | Boston Scientific Scimed, Inc. | Endoprosthesis coating |
US8221822B2 (en) | 2007-07-31 | 2012-07-17 | Boston Scientific Scimed, Inc. | Medical device coating by laser cladding |
US8231980B2 (en) | 2008-12-03 | 2012-07-31 | Boston Scientific Scimed, Inc. | Medical implants including iridium oxide |
US8287937B2 (en) | 2009-04-24 | 2012-10-16 | Boston Scientific Scimed, Inc. | Endoprosthese |
US8353949B2 (en) | 2006-09-14 | 2013-01-15 | Boston Scientific Scimed, Inc. | Medical devices with drug-eluting coating |
US8431149B2 (en) | 2007-03-01 | 2013-04-30 | Boston Scientific Scimed, Inc. | Coated medical devices for abluminal drug delivery |
US8449603B2 (en) | 2008-06-18 | 2013-05-28 | Boston Scientific Scimed, Inc. | Endoprosthesis coating |
US8574615B2 (en) | 2006-03-24 | 2013-11-05 | Boston Scientific Scimed, Inc. | Medical devices having nanoporous coatings for controlled therapeutic agent delivery |
US8771343B2 (en) | 2006-06-29 | 2014-07-08 | Boston Scientific Scimed, Inc. | Medical devices with selective titanium oxide coatings |
US8815275B2 (en) | 2006-06-28 | 2014-08-26 | Boston Scientific Scimed, Inc. | Coatings for medical devices comprising a therapeutic agent and a metallic material |
US8815273B2 (en) | 2007-07-27 | 2014-08-26 | Boston Scientific Scimed, Inc. | Drug eluting medical devices having porous layers |
US8900292B2 (en) | 2007-08-03 | 2014-12-02 | Boston Scientific Scimed, Inc. | Coating for medical device having increased surface area |
US8920491B2 (en) | 2008-04-22 | 2014-12-30 | Boston Scientific Scimed, Inc. | Medical devices having a coating of inorganic material |
US8932346B2 (en) | 2008-04-24 | 2015-01-13 | Boston Scientific Scimed, Inc. | Medical devices having inorganic particle layers |
US9284409B2 (en) | 2007-07-19 | 2016-03-15 | Boston Scientific Scimed, Inc. | Endoprosthesis having a non-fouling surface |
Families Citing this family (106)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2178541C (en) | 1995-06-07 | 2009-11-24 | Neal E. Fearnot | Implantable medical device |
US6582392B1 (en) | 1998-05-01 | 2003-06-24 | Ekos Corporation | Ultrasound assembly for use with a catheter |
US6676626B1 (en) | 1998-05-01 | 2004-01-13 | Ekos Corporation | Ultrasound assembly with increased efficacy |
US8177743B2 (en) * | 1998-05-18 | 2012-05-15 | Boston Scientific Scimed, Inc. | Localized delivery of drug agents |
CA2350638C (en) | 1998-09-11 | 2009-11-24 | Gerhard Schmidmaier | Biologically active implants coated with a biodegradable polymer |
US6719805B1 (en) * | 1999-06-09 | 2004-04-13 | C. R. Bard, Inc. | Devices and methods for treating tissue |
US20070032853A1 (en) | 2002-03-27 | 2007-02-08 | Hossainy Syed F | 40-O-(2-hydroxy)ethyl-rapamycin coated stent |
US7807211B2 (en) * | 1999-09-03 | 2010-10-05 | Advanced Cardiovascular Systems, Inc. | Thermal treatment of an implantable medical device |
US7682647B2 (en) | 1999-09-03 | 2010-03-23 | Advanced Cardiovascular Systems, Inc. | Thermal treatment of a drug eluting implantable medical device |
US8632845B2 (en) * | 2000-12-28 | 2014-01-21 | Abbott Cardiovascular Systems Inc. | Method of drying bioabsorbable coating over stents |
US8277868B2 (en) * | 2001-01-05 | 2012-10-02 | Abbott Cardiovascular Systems Inc. | Balloon catheter for delivering therapeutic agents |
US6544223B1 (en) * | 2001-01-05 | 2003-04-08 | Advanced Cardiovascular Systems, Inc. | Balloon catheter for delivering therapeutic agents |
US20020119178A1 (en) * | 2001-02-23 | 2002-08-29 | Luc Levesque | Drug eluting device for treating vascular diseases |
WO2002065946A1 (en) * | 2001-02-23 | 2002-08-29 | Angiogene Inc. | Apparatus for loading a therapeutic agent onto an endovascular device |
US7727221B2 (en) | 2001-06-27 | 2010-06-01 | Cardiac Pacemakers Inc. | Method and device for electrochemical formation of therapeutic species in vivo |
JP2003135588A (ja) * | 2001-11-08 | 2003-05-13 | Univ Nihon | 経皮経管的ドラッグデリバリーデバイス |
AU2002359576A1 (en) | 2001-12-03 | 2003-06-17 | Ekos Corporation | Catheter with multiple ultrasound radiating members |
US7141044B2 (en) | 2001-12-11 | 2006-11-28 | Ekos Corporation | Alternate site gene therapy |
US8226629B1 (en) | 2002-04-01 | 2012-07-24 | Ekos Corporation | Ultrasonic catheter power control |
US7192484B2 (en) | 2002-09-27 | 2007-03-20 | Surmodics, Inc. | Advanced coating apparatus and method |
USRE40722E1 (en) | 2002-09-27 | 2009-06-09 | Surmodics, Inc. | Method and apparatus for coating of substrates |
US7125577B2 (en) | 2002-09-27 | 2006-10-24 | Surmodics, Inc | Method and apparatus for coating of substrates |
US6921371B2 (en) | 2002-10-14 | 2005-07-26 | Ekos Corporation | Ultrasound radiating members for catheter |
JP2006514848A (ja) | 2002-11-13 | 2006-05-18 | セタゴン インコーポレーティッド | 多孔質層を有する医療装置およびその作製方法 |
US9770349B2 (en) | 2002-11-13 | 2017-09-26 | University Of Virginia Patent Foundation | Nanoporous stents with enhanced cellular adhesion and reduced neointimal formation |
US20060121080A1 (en) | 2002-11-13 | 2006-06-08 | Lye Whye K | Medical devices having nanoporous layers and methods for making the same |
US20050079199A1 (en) * | 2003-02-18 | 2005-04-14 | Medtronic, Inc. | Porous coatings for drug release from medical devices |
EP1596895B1 (de) * | 2003-02-18 | 2009-02-04 | Medtronic, Inc. | Verschlussbeständiger hydrocephalischer shunt |
EP1449546B1 (de) * | 2003-02-21 | 2010-10-27 | Sorin Biomedica Cardio S.R.L. | Verfahren zur Herstellung eines Stents und entsprechender Stent |
EP1475110A1 (de) * | 2003-05-09 | 2004-11-10 | B. Braun Melsungen Ag | Stent zur kontrollierten Abgabe von Wirkstoffen |
US20050118344A1 (en) | 2003-12-01 | 2005-06-02 | Pacetti Stephen D. | Temperature controlled crimping |
US20050137520A1 (en) * | 2003-10-29 | 2005-06-23 | Rule Peter R. | Catheter with ultrasound-controllable porous membrane |
US7803178B2 (en) | 2004-01-30 | 2010-09-28 | Trivascular, Inc. | Inflatable porous implants and methods for drug delivery |
US7699832B2 (en) * | 2004-05-27 | 2010-04-20 | Medtronic, Inc. | Medical device having a surface including a biologically active agent therein, and methods |
EP1773893B1 (de) * | 2004-08-03 | 2010-06-02 | Agency for Science, Technology and Research | Polymer mit miteinander verbundenen poren zur arzneistoffzufuhr und verfahren |
US7507433B2 (en) * | 2004-09-03 | 2009-03-24 | Boston Scientific Scimed, Inc. | Method of coating a medical device using an electrowetting process |
US20060051392A1 (en) * | 2004-09-03 | 2006-03-09 | Medtronic, Inc. | Porous coatings for drug release from medical devices |
US20060051393A1 (en) * | 2004-09-08 | 2006-03-09 | Medtronic, Inc. | Method of manufacturing drug-eluting medical device |
US7901451B2 (en) | 2004-09-24 | 2011-03-08 | Biosensors International Group, Ltd. | Drug-delivery endovascular stent and method for treating restenosis |
US7862835B2 (en) | 2004-10-27 | 2011-01-04 | Boston Scientific Scimed, Inc. | Method of manufacturing a medical device having a porous coating thereon |
US7958840B2 (en) | 2004-10-27 | 2011-06-14 | Surmodics, Inc. | Method and apparatus for coating of substrates |
US7964209B2 (en) | 2004-12-07 | 2011-06-21 | Boston Scientific Scimed, Inc. | Orienting polymer domains for controlled drug delivery |
US20060124466A1 (en) * | 2004-12-09 | 2006-06-15 | Scimed Life Systems, Inc. | Method and apparatus for coating a medical device by electroplating |
US8535702B2 (en) | 2005-02-01 | 2013-09-17 | Boston Scientific Scimed, Inc. | Medical devices having porous polymeric regions for controlled drug delivery and regulated biocompatibility |
EP1893130A4 (de) * | 2005-06-17 | 2015-08-26 | Georgia Tech Res Inst | Beschichtete mikrostrukturen und verfahren zu ihrer herstellung |
EP2345376B1 (de) * | 2005-09-30 | 2012-07-04 | Cook Medical Technologies LLC | Beschichtete Gefässverschlussvorrichtung |
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EP2959925B1 (de) | 2006-09-15 | 2018-08-29 | Boston Scientific Limited | Medizinische vorrichtungen und verfahren zu ihrer herstellung |
ES2368125T3 (es) | 2006-09-15 | 2011-11-14 | Boston Scientific Scimed, Inc. | Endoprótesis bioerosionable con capas inorgánicas bioestables. |
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EP2277563B1 (de) | 2006-12-28 | 2014-06-25 | Boston Scientific Limited | Biologisch abbaubare endoprothesen und verfahren zur herstellung derselben. |
CN101209360B (zh) * | 2006-12-29 | 2012-06-20 | 微创医疗器械(上海)有限公司 | 一种生物支架的制备方法 |
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Also Published As
Publication number | Publication date |
---|---|
US6652581B1 (en) | 2003-11-25 |
JP2002519139A (ja) | 2002-07-02 |
ATE384502T1 (de) | 2008-02-15 |
ES2169012T1 (es) | 2002-07-01 |
CA2336650A1 (en) | 2000-01-13 |
CA2336650C (en) | 2008-01-29 |
US20070299509A1 (en) | 2007-12-27 |
EP1096902A1 (de) | 2001-05-09 |
DE69938047D1 (de) | 2008-03-13 |
WO2000001322A1 (en) | 2000-01-13 |
EP1096902B1 (de) | 2008-01-23 |
US7758909B2 (en) | 2010-07-20 |
US20040067301A1 (en) | 2004-04-08 |
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