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Publication numberCN1625428 A
Publication typeApplication
Application numberCN 03803019
PCT numberPCT/US2003/000066
Publication date8 Jun 2005
Filing date2 Jan 2003
Priority date31 Jan 2002
Also published asCA2474858A1, CA2474858C, CA2474980A1, CA2474980C, CN1278757C, CN1280001C, CN1625434A, DE60319810D1, DE60320542D1, DE60320542T2, EP1483028A2, EP1483028A4, EP1483028B1, EP1483039A1, EP1483039A4, EP1483039B1, US6835311, US6913154, US6953604, US6959820, US6998058, US7008537, US7011753, US7144533, US20030168401, US20030196963, US20030196964, US20030201231, US20030205529, US20030205530, US20030205531, US20030213750, WO2003063996A2, WO2003063996A3, WO2003064013A1
Publication number03803019.5, CN 03803019, CN 1625428 A, CN 1625428A, CN-A-1625428, CN03803019, CN03803019.5, CN1625428 A, CN1625428A, PCT/2003/66, PCT/US/2003/000066, PCT/US/2003/00066, PCT/US/3/000066, PCT/US/3/00066, PCT/US2003/000066, PCT/US2003/00066, PCT/US2003000066, PCT/US200300066, PCT/US3/000066, PCT/US3/00066, PCT/US3000066, PCT/US300066
InventorsEE科斯洛
Applicant科斯洛技术公司
Export CitationBiBTeX, EndNote, RefMan
External Links: SIPO, Espacenet
Precoat filter media, and methods of making and using
CN 1625428 A
Abstract  translated from Chinese
本发明涉及包括微生物拦截增强过滤助剂的预涂层或主体原料组合物。 The present invention relates to a microbiological interception enhanced filter aid precoat or body feed composition. 优选微生物拦截增强过滤助剂包括在其至少一部分表面上涂布微生物拦截增强剂的原纤化Lyocell纳米纤维。 Preferably microbiological interception enhanced filter aid comprises at least a portion of its surface coated with a microbiological interception enhancing agent fibrillated Lyocell nanofibers. 微生物拦截增强剂包括与生物活性金属结合的阳离子材料。 Microbiological interception enhancers include bioactive metal cation binding material. 单独或与主体未处理的过滤助剂结合采用微生物拦截增强过滤助剂实现细菌拦截至少约4的对数下降。 Alone or with the main use of untreated filter aid combined to achieve microbiological interception enhanced filter aid intercept bacteria log reduction of at least about 4. 包括微生物拦截增强过滤助剂的预涂层可用于饮料的一步冷冻灭菌。 Including microbiological interception enhanced filter aid sterilization step freezing can be used for precoat beverage.
Claims(21)  translated from Chinese
1.一种组合物,它包括过滤助剂,其中在该过滤助剂的至少一部分上涂布具有与其缔合的抗衡离子的阳离子材料,其中用与所述阳离子材料直接相邻的抗衡离子沉淀生物活性金属。 1. A composition which comprises a filter aid, wherein at least a portion coated with the filter aid material having a cationic counterion associated therewith, wherein said precipitated cationic material directly adjacent counterion bioactive metal.
2.权利要求1的组合物,其中在过滤之前,使用所述过滤助剂以在隔膜上形成滤饼。 The composition of claim 1, wherein prior to filtration to form a filter cake on the membrane using the filter aid.
3.权利要求1的组合物,其中所述过滤助剂作为主体原料成分与流入液结合。 The composition of claim 1, wherein the filter aid as a main raw material component in combination with the inflow liquid.
4.权利要求1的组合物,其中所述过滤助剂包括加拿大标准游离度小于或等于约45的纤维。 The composition of claim 1, wherein the filter aid comprises a Canadian Standard Freeness of less than or equal to about 45 fibers.
5.权利要求1的组合物,其中所述过滤助剂包括纳米纤维、纤维素、硅藻土、活性炭、活化矾土、硅酸盐、聚合物树脂或纤维、或其组合。 The composition of claim 1, wherein the filter aid comprises nanofibers, cellulose, diatomaceous earth, activated carbon, activated alumina, silicates, polymeric resins or fibers, or combinations thereof.
6.权利要求1的组合物,其中使所述过滤助剂与未处理的过滤助剂材料混合。 The composition of claim 1, in which the aid to the untreated filter aid material of the mixture was filtered.
7.一种组合物,它包括:吸附剂;与所述吸附剂混合的过滤助剂,所述过滤助剂在其至少一部分上涂布具有与其缔合的抗衡离子的阳离子材料和用与该阳离子材料直接相邻的抗衡离子沉淀的生物活性金属。 A composition comprising: an adsorbent; mixed with the adsorbent filter aid, the filter aid material having a cationic counterion associated therewith at least a portion thereof with the coating and cation material directly adjacent counterion precipitated bioactive metal.
8.权利要求1或7的组合物,其中阳离子材料具有高的电荷密度,分子量大于约500道尔顿,和包括季铵化胺、季铵化酰胺、季铵盐、季铵化酰亚胺、苄烷铵化合物、阳离子氨基硅化合物、其聚合物,或其组合。 1 or composition of claim 7, wherein the cationic material has a high charge density, a molecular weight of greater than about 500 Daltons, and include quaternized amines, quaternized amides, quaternary ammonium salts, quaternized imides , benzalkonium compounds, cationic amino silicone compounds, polymers thereof, or combinations thereof.
8.权利要求1或7的组合物,其中阳离子材料是二烯丙基二甲基卤化铵的均聚物。 1 or composition of claim 7, wherein the cationic material is a diallyl dimethyl ammonium halide homopolymer.
9.权利要求1或7的组合物,其中生物活性金属是银、铜、锌、镉、汞、锑、金、铝、铂、钯或其组合。 The composition of claim 1 or 7, wherein the biologically active metal is silver, copper, zinc, cadmium, mercury, antimony, gold, aluminum, platinum, palladium or a combination thereof.
10.权利要求7的组合物,其中所述吸附剂包括纤维素纤维,和其中所述过滤助剂包括加拿大标准游离度小于或等于约100的原纤化Lyocell纤维。 10. The composition of claim 7, wherein said adsorbent comprises cellulose fibers, and wherein said filter aid comprises a Canadian Standard Freeness of less than or equal to about fibrillated Lyocell fiber 100.
11.一种过滤流入液的方法:提供支撑介质;用过滤助剂涂布该支撑介质,以形成预涂层,其中该过滤助剂在其至少一部分上涂布具有与其缔合的抗衡离子的阳离子材料和用与阳离子材料直接相邻的抗衡离子沉淀的生物活性金属;使流入液经过所述预涂层;在预涂层上保留来自流入液的污染物;和获得澄清的流出液。 11. A method of filtering influent: providing a support medium; filter aid coated with the support medium to form a precoat layer, wherein the filter aid coated on at least a portion having associated therewith a counter ion cation materials and the use of cationic materials directly adjacent counter ion precipitation of bioactive metal; liquid flowing through the pre-coating; retain pollutants from flowing into the liquid in the pre-coat; and access to the effluent clarification.
12.权利要求11的方法,进一步包括在使流入液经过预涂层之前,添加过滤助剂到流入液中的步骤。 12. The method of claim 11, further comprising flowing the liquid through the precoat layer prior to adding a filter aid to the influent of step.
13.权利要求11的方法,其中在用过滤助剂涂布支撑介质的步骤中,所述过滤助剂包括纳米纤维、纤维素、硅藻土、活性炭、活化矾土、硅酸盐、聚合物树脂或纤维、或其组合。 13. The method of claim 11, wherein the support medium with the filter aid coating step, the filter aid comprises nanofibers, cellulose, diatomaceous earth, activated carbon, activated alumina, silicates, polymers resins or fibers, or combinations thereof.
14.权利要求11的方法,其中在用过滤助剂涂布支撑介质的步骤中,使所述过滤助剂与未处理的过滤助剂材料混合。 14. The method of claim 11, wherein the step of coating the support medium with the filter aid, making aid untreated filter aid material the mixture was filtered.
15.权利要求11的方法,其中在用过滤助剂涂布支撑介质的步骤中,用阳离子材料涂布所述过滤助剂,其中所述阳离子材料选自季铵化胺、季铵化酰胺、季铵盐、季铵化酰亚胺、苄烷铵化合物、阳离子氨基硅化合物、其聚合物和其组合。 15. The method of claim 11, wherein in step with a filter aid coated support medium, coating the material with a cation filter aid, wherein the cationic material is selected from quaternized amines, quaternized amides, quaternary ammonium salts, quaternized imides, benzalkonium compounds, cationic amino silicone compounds, polymers thereof, and combinations thereof.
16.权利要求11的方法,其中在用过滤助剂涂布支撑介质的步骤中,用二烯丙基二甲基卤化铵的均聚物涂布所述过滤助剂。 16. The method of claim 11, wherein the support medium with the filter aid coating step, with diallyl dimethyl ammonium halide homopolymers coating the filter aid.
17.权利要求11的方法,其中在用过滤助剂涂布支撑介质的步骤中,所述生物活性金属是银、铜、锌、镉、汞、锑、金、铝、铂、钯或其组合。 17. The method of claim 11, wherein the support medium with the filter aid coating step, the biologically active metal is silver, copper, zinc, cadmium, mercury, antimony, gold, aluminum, platinum, palladium or a combination thereof .
18.权利要求11的方法,进一步包括提供流入液中微生物污染物至少约4的对数下降的步骤。 18. The method of claim 11, further comprising the step of providing fluid flow into a log reduction of microbial contaminants at least about 4.
19.基本上如本文任何实施例中所述的权利要求1或7的组合物。 19. A substantially as claimed in any of the embodiments described herein the composition of claim 1 or 7.
20.基本上如本文任何实施例中所述的权利要求11的方法。 20. The method of claim 11 substantially as herein described in any of the embodiments of claims.
Description  translated from Chinese
预涂层过滤介质及制备和使用方法 Precoat filter media and methods of making and using

本发明涉及用于从液体、尤其是饮料中分离固体的预涂层过滤体系中有用的过滤助剂。 The present invention relates to the liquid, in particular beverage separating solids precoat filtration system useful filter aid.

过滤的机械方法典型地通过物理排阻操作。 Mechanical means, typically by filtration physical exclusion operation. 污染的流入液流经多孔介质,所述多孔介质保留尺寸比多孔介质孔径大的颗粒并允许含有尺寸小于多孔介质孔径的颗粒的流出液流过。 Contaminated influent solution stream through the porous medium, the porous medium to retain larger size particles than the pore diameter of the porous medium and allowed effluent stream containing porous medium pore size smaller than the particles too. 在截留被污染的流入液中的最小可能颗粒与流入液流经多孔介质的流速之间存在平衡,其中必须实现该平衡,以提供高的产量。 Retentate contaminated liquid flows into the smallest possible particles to flow into the liquid flow exists a balance between the flow rate through the porous medium, wherein the balance must be achieved in order to provide a high yield.

已知现有技术使用多孔床或粉末过滤体系过滤饮料、尤其是发酵饮料。 Known in the prior art using a porous bed or powder filtration system filtering beverages, particularly fermented beverages. 例如,啤酒或白酒在发酵后被过滤以除去酵母和其它引起混浊的材料,以实现胶体和微生物的稳定性。 For example, in the fermentation beer or liquor after filtration to remove yeast and other turbidity causing materials in order to achieve colloidal and microbiological stability. 在粉末过滤过程中,在隔膜上形成过滤助剂的预涂层,一种通常具有特定孔径的多孔材料如硅藻土或纤维素纤维。 Powder filtration process, the membrane is formed on the precoat layer of filter aid, usually having a particular pore size of the porous material such as diatomaceous earth or cellulose fibers. 当过滤助剂的分散液流过隔膜时,太大的过滤助剂纤维或颗粒不能流过隔膜的孔,结果在隔膜上累积,从而形成滤饼。 When the filter aid is dispersed to flow through the membrane, much filter aid fibers or particles can not flow through the membrane pores, resulting in the accumulation on the membrane, thereby forming a filter cake. 比隔膜孔小的过滤助剂纤维或颗粒将最终在较大过滤助剂纤维或颗粒后面存留,从而在滤饼内提供用于最佳过滤的孔径分布。 Smaller than the membrane pore filter aid fibers or particles will end up in the fibers or particles retained behind the larger filter aid, thus providing for optimum pore size distribution within the filter cake.

为了提供流体的深度精制,单次过滤流过是不足的,因此,需要多次过滤步骤。 In order to provide refined fluid flow through a single filter is insufficient, therefore, require multiple filtration step. 为了除去微生物污染物,如在制备发酵饮料中使用的酵母,过滤器的孔径必须小于10微米。 To remove microbiological contaminants, such as those used in the preparation of a yeast fermented beverage, the filter pore size must be less than 10 microns. 此外,冷冻灭菌技术要求小于约2微米的孔径。 Moreover, technical requirements for freezing sterilization pore size of less than about 2 microns. 使用预涂层的现有技术的过滤体系,在没有使用多步过滤步骤提供流体的深度精制或提供单步冷冻灭菌流体方面,尚未获得成功。 Precoat filter system using existing technology, without the use of a multi-step filtration steps for providing fluid refined or provide one-step freezing sterilization fluid, yet successful.

发明概述第一方面,本发明涉及包括过滤助剂的组合物,其中在该过滤助剂的至少一部分上涂布具有与其缔合的抗衡离子的阳离子材料,其中用与阳离子材料直接相邻的抗衡离子沉淀生物活性金属。 SUMMARY OF THE INVENTION The first aspect of the counter, the present invention relates to a composition comprising a filter aid, wherein at least a portion coated with the filter aid material having a cationic counterion associated therewith, wherein directly adjacent material with cationic bioactive metal ion precipitation.

另一方面,本发明涉及包括下述的组合物:吸附剂、与吸附剂混合的过滤助剂,该过滤助剂在其至少一部分上涂布具有与其缔合的抗衡离子的阳离子材料和用与该阳离子材料直接相邻的抗衡离子沉淀的生物活性金属。 Another aspect, the present invention relates to a composition comprising: an adsorbent, the adsorbent mixed with filter aid, the filter aid coated on at least a portion having associated therewith a counter ion with the cation material and The material is directly adjacent to the cationic counterion precipitated bioactive metal.

再一方面,本发明涉及过滤流入液的方法:提供支撑介质;用过滤助剂涂布该支撑介质,以形成预涂层,其中该过滤助剂在其至少一部分上涂布具有与其缔合的抗衡离子的阳离子材料和用与阳离子材料直接相邻的抗衡离子沉淀的生物活性金属;使流入液流过预涂层;在预涂层上保留来自流入液的污染物;和获得澄清的流出液。 A further aspect, the present invention relates to a method of filtering influent: providing a support medium; filter aid coated with the support medium to form a precoat layer, wherein the filter aid coated on at least a portion having associated therewith cationic counterions and the use of the material with a cationic material directly adjacent counterion precipitated bioactive metal; flowing to flow through the precoat layer; retain contaminants from the influent in the precoat layer; and to obtain a clear effluent .

优选实施方案的详述定义在整个说明书中,单数或复数形式的下述术语具有下述含义。 Detailed Description of the preferred embodiments is defined throughout this specification, the singular or plural form, the following terms have the following meanings.

″吸附剂″是指能够主要通过将杂质吸引到其内部结构内而吸附杂质的任何材料。 "Adsorbent" refers to any material capable of primarily impurities sucked into the internal structure of adsorbed impurities.

″吸附剂″是指能够主要通过物理吸附到其表面上而吸附杂质的任何材料。 "Adsorbent" refers to the ability primarily by physical adsorption to any material on its surface adsorbed impurities.

“主体(bulk)过滤助剂”是指没有电荷改性的常规用作预涂层的材料和/或主体原料成分的那些材料。 "Body (bulk) filter aid" means a material conventionally used as pre-coat and / those materials which do not have a charge-modified or ingredients of the body. 这些材料包括但不限于活性炭、珍珠岩、硅藻土、纤维素、二氧化硅和类似物。 These materials include, but are not limited to activated charcoal, perlite, diatomaceous earth, cellulose, silicon dioxide and the like.

″污染物下降″是指以化学、机械或生物方式减少被拦截、除去、和/或惰性化的流体中的杂质,以使得该流体更安全地,例如用于人类使用,或在工业场合更有用。 "Contaminants down" refers to the chemical, mechanical or biological way to reduce is intercepted, removed, and / or deactivation of the impurities in the fluid, so that the fluid is more secure, for example, for human use, or more in industrial applications it works.

“纤维”是指特征在于高长径比例如几百比一的固体。 "Fiber" means characterized by a high aspect ratio such as several hundred to one solid. 有关纤维的任何讨论包括晶须。 Any discussion of fibers includes whiskers.

“过滤助剂”或“过滤助剂材料”是指用于从流体中除去污染物的预涂层过滤体系中可使用的材料。 "Filter aid" or "filter aid material" means a material for precoat filtration system that can be used contaminants removed from the fluid.

“过滤介质”是指进行流体过滤的材料。 "Filter media" refers to the fluid filtration material.

“流体”是指液体、气体或其结合。 "Fluid" refers to combining a liquid, gas, or.

″拦截(intercept)″或″拦截(interception)″认为是指干预或阻止流过,以实现改变、除去、灭活或影响。 "Intercept (intercept)" or "interception (interception)" refers to intervene or prevent think flows in order to achieve change, remove, inactivation or influence.

″对数下降值″或″LRV″是指在流入液中的生物体数目除以在过滤器的流出液中的生物体数目的常用对数值。 "Log reduction" or "LRV" refers to the number of organisms in the influent divided by the filter effluent in the number of organisms in a common logarithm value.

″微生物拦截增强过滤助剂″是指包括带正电的过滤助剂的过滤助剂或它的一部分,其中在该过滤助剂的至少一部分上涂布与生物活性金属组合的阳离子材料。 "Microbiological interception enhanced filter aid" means a filter aid comprising positively charged filter aid or a portion thereof, coated with the composition of the bioactive metal cation material wherein at least a portion of the filter aid. 可添加额外的添加剂,以制备在其目的应用中更有用的微生物拦截增强过滤助剂。 Additional additives may be added to prepare an object of application in the more useful microbiological interception enhanced filter aid.

″微生物拦截增强剂″是指具有与其缔合的抗衡离子的阳离子材料与生物活性金属的组合。 "Microbiological interception enhancing agent" refers to a combination of a cationic material having a counter ion associated therewith and the bioactive metal.

“微生物”是指可悬浮在流体中的任何活的生物体,包括但不限于细菌,病毒,真菌,原生动物,及其繁殖形式,包括孢囊和孢子。 "Microbial" refers to suspension in the fluid of any living organism, including but not limited to, bacteria, viruses, fungi, protozoa, and reproductive forms, including cysts and spores.

″颗粒″是指尺寸范围从胶体至肉眼可见,且对形状没有特别限制但一般具有有限长/宽比的固体。 "Particles" refers to the size range from colloidal to macroscopic, and the shape is not particularly limited but generally have a limited length / width ratio of the solid.

″晶须″是指具有有限的长径比且介于颗粒和纤维的长径比之间的一种长丝。 "Whiskers" means having a limited aspect ratio and a filament between the particles and between the fibers of aspect ratio. 有关纤维的任何讨论包括晶须。 Any discussion of fibers includes whiskers.

通用的预涂层组合物的特征本发明的预涂层组合物包括微生物拦截增强过滤助剂,其中使用合适的孔结构和化学处理的组合,该过滤助剂提供增强的过滤,包括微生物拦截能力。 Precoat composition is characterized in general precoat compositions of the present invention includes a microbiological interception enhanced filter aid, in which a suitable combination of pore structure and chemical treatment of the filter aid provides enhanced filtration, including microbiological interception capability . 微生物拦截增强过滤助剂当用作预涂层组合物的唯一成分时,提供小于约2微米的孔径,和可以小于约1微米。 When the microbiological interception enhanced filter aid, when used as the sole component precoat composition, there is provided a pore size of less than about 2 microns, and may be less than about 1 micron. 当与主体过滤助剂结合使用时,微生物拦截增强过滤助剂增强过滤器性能,延长过滤器寿命,并提供更坚实的滤饼。 When using the filter aid in combination with the body, the microbiological interception enhanced filter aid to enhance filter performance, extended filter life, and to provide a more solid cake. 当微生物拦截增强过滤助剂与主体过滤助剂混合时,在至少一部分该材料上的孔径和电荷使得可拦截较小的污染物。 When the microbiological interception enhanced filter aid and the filter aid mixing body, on at least a portion of the material so that pore size and charge can intercept smaller contaminants. 通过以变化的用量组合微生物拦截增强过滤助剂与主体过滤助剂,可满足特定的过滤需求。 By varying the amount of a combination of microbiological interception enhanced filter aid and the main filter aid can meet specific filtration needs. 微生物拦截增强过滤助剂也可用作主体原料成分。 Microbiological interception enhanced filter aid is also used as the main ingredients.

微生物拦截增强过滤助剂包括能具有小于约2.0微米的平均流动通道的任何材料。 Microbiological interception enhanced filter aid can comprise less than about 2.0 microns average flow path of any material. 优选地,微生物拦截增强过滤助剂包括用微生物拦截增强剂处理的单独的或结合的纳米纤维和/或晶须,或活性颗粒。 Preferably, the microbiological interception enhanced filter aid alone or in combination include nanofibers with a microbiological interception enhancing agent treatment and / or whiskers, or active particles. 由本发明的预涂层组合物提供的所得滤饼的致密孔结构提供从流体到滤饼表面的短扩散距离。 Dense pore structure of the resulting cake was provided by pre-coating composition of the present invention provides short diffusion distances from the fluid to the cake surface. 处理微生物拦截增强过滤助剂所使用的化学处理方法利用阳离子材料与生物活性金属之间的协同相互作用,即当它们结合时,提供接触时的微生物污染物的广谱下降。 Processing microbiological interception enhanced chemical treatment method used filter aid materials and the use of cationic bioactive synergistic interaction between the metal, i.e., when they are combined, provide a broad spectrum of microbial contaminants decrease the time of contact. 阳离子材料提供给微生物拦截增强过滤助剂的电荷将提供微生物污染物的增强的电动拦截,而致密的孔结构提供短的扩散路径,并进而提供在流向预涂层组合物表面的流动流体内污染物的快速扩散动力学。 Cation material supplied to the microbiological interception enhanced filter aid charge will provide enhanced electric interception of microbiological contaminants, while the tight pore structure provides a short diffusion path, and thus provide a pre-coating composition in the flow surface of the flow of the fluid contamination material fast diffusion kinetics. 微生物拦截增强过滤助剂还提供微生物污染物的补充直接机械拦截。 Microbiological interception enhanced filter aid also provides supplemental microbial contaminants direct mechanical interception.

微生物拦截增强过滤助剂可由能在其表面的至少一部分上保留电荷的任何材料组成,其中电荷保留通过流动或ξ电势来确定。 Microbiological interception enhanced filter aid may be any material that can retain charges on its surface at least a portion of the composition, wherein the flow of charge retention by or ξ potential determined. 当预涂层组合物用于过滤饮料时,在水中不溶的食品安全的亲水材料是优选的。 When the pre-coating composition for filtering beverages, food safety in water insoluble hydrophilic materials are preferred. 微生物拦截增强过滤助剂可以是有机或无机纤维、晶须、粉末和/或颗粒。 Microbiological interception enhanced filter aids can be organic or inorganic fibers, whiskers, powders and / or granules. 优选微生物拦截增强过滤助剂可由活性炭、珍珠岩、硅藻土、纤维素、二氧化硅和类似物组成。 Preferably microbiological interception enhanced filter aid may be activated carbon, perlite, diatomaceous earth, cellulose, silica and the like components. 处理微生物拦截增强过滤助剂所使用的化学处理方法利用阳离子材料与生物活性金属之间的协同相互作用,即当它们组合时,提供细菌污染物至少约3的对数下降。 Processing microbiological interception enhanced chemical processing method using a filter aid used cationic materials synergistic interaction between the metal and bioactivity, i.e., when they are combined, provide at least about 3 log reduction of bacterial contaminants. 由阳离子材料提供给微生物拦截增强过滤助剂的电荷支持细菌污染物和在流出液中非所需的其它带负电的颗粒的电动拦截。 Provided by the cationic material to the microbiological interception enhanced filter aid charge support bacterial contaminants and other desired electric effluent Central Africa negatively charged particles intercepted.

过滤助剂材料本发明的预涂层组合物包括微生物拦截增强过滤助剂,该过滤助剂在其至少一部分上涂布具有与其缔合的抗衡离子的阳离子材料和用与该阳离子材料直接相邻的抗衡离子沉淀的生物活性金属。 The filter aid material of the present invention, the pre-coating composition comprising a microbiological interception enhanced filter aid, the filter aid coated on at least a portion of a cationic material having a counter ion associated therewith and with the material directly adjacent to the cation counterions precipitated bioactive metal. 优选微生物拦截增强过滤助剂由多根纳米纤维和/或有机与无机材料的颗粒成分组成,其中所述材料包括但不限于聚合物、离子交换树脂、工程树脂、陶瓷、纤维素、云母、玻璃、金属、活化矾土、碳或活性炭、二氧化硅、沸石、硅藻土、珍珠岩、活性铝土矿、漂白土、钙羟基磷灰石、其它吸附材料或其结合。 Preferably microbiological interception enhanced filter aid from a plurality of nanofibers and / or particle component composed of organic and inorganic materials, wherein the materials include, but are not limited to polymers, ion-exchange resins, engineered resins, ceramics, cellulose, mica, glass , metal, activated alumina, carbon or activated carbon, silica, zeolite, diatomaceous earth, perlite, activated bauxite, fuller's earth, calcium hydroxyapatite, other absorbent materials or combinations thereof. 可以考虑有机和无机纤维和/或晶须或颗粒的结合且在本发明的范围内,例如可与能配制到预涂层组合物内的非常小的粒状吸附剂或颗粒一起使用玻璃、陶瓷、金属纤维和聚合物纤维。 Can be considered organic and inorganic fibers and / or a combination whiskers or particles and within the scope of the present invention, for example, can be formulated into very small with granular or particulate adsorbent within the pre-coating composition for use with glass, ceramics, metal fibers and polymeric fibers.

预涂层组合物可以完全由微生物拦截增强过滤助剂组成或可仅仅含有一部分所述助剂。 Precoat composition may entirely by microbiological interception enhanced filter aid composition or may contain only a portion of the aid. 预涂层组合物的一个优选实施方案包括根据本发明处理的基本上为纳米纤维的过滤助剂材料。 A preferred embodiment of the pre-coating composition comprises a substantially nanofiber filter aid material treated according to the present invention. 优选纳米纤维是加拿大标准游离度小于或等于约100和最优选小于或等于约45的纤维素或聚合物纤维。 Preferably nanofiber is a Canadian Standard Freeness of less than or equal to about 100 and most preferably less than or equal to about 45 cellulose or polymer fibers of. 优选大部分纤维的直径应当小于或等于约1000纳米,更优选小于或等于约400纳米,和最优选直径小于或等于约250纳米的纤维。 Most preferably the fiber diameter should be less than or equal to about 1000 nanometers, more preferably less than or equal to about 400 nanometers, and most preferably a diameter less than or equal to about 250 nm fiber. 优选切断纤维到约1mm至约8mm的长度,优选约2mm至约6mm,和更优选约3mm至约4mm。 Preferably the staple fibers to a length of about 1mm to about 8mm, preferably about 2mm to about 6mm, and more preferably from about 3mm to about 4mm. 最优选原纤化纤维,这是因为它们特别小的尺寸和潜在的低成本。 Most preferably fibrillated fibers, because of their extremely small size and potential low cost.

优选地,根据本发明加工的原纤化合成纤维素纤维可产生在本发明的预涂层组合物中使用的超细亲水微生物拦截过滤助剂。 Preferably, the microorganism can produce ultra-fine hydrophilic coating composition in the pre-use in the present invention according to fibrillated synthetic cellulosic fibers of the present invention is processed intercepting filter aid. 可通过在有机溶剂如氧化胺中直接溶解和纺丝木浆来制备这种原纤化纤维素纤维,和它被称为Lyocell纤维。 Can be prepared by oxidation of the amine in an organic solvent such as direct dissolution and spinning of wood pulp to prepare such fibrillated cellulose fibers, and it is known as Lyocell fibers. Lyocell纤维的优点是以一致、均匀的方式生产,从而得到可重复的结果,这与例如天然纤维素纤维的情况不同。 Lyocell fiber is to the advantage of consistent, uniform manner of production, to obtain reproducible results, which is the case of natural cellulose fibers such as different. 此外,Lyocell的原纤常常卷曲。 Furthermore, Lyocell fibrils often crimped. 卷曲提供大量的纤维缠结,从而导致显著残留的湿强度。 Provide a large number of curled fiber entanglement, resulting in a significant residual wet strength. 另外,可使用中等投资成本的设备大量地生产原纤化Lyocell纤维。 In addition, you can use a large number of moderate investment cost equipment production fibrillation Lyocell fibers. 应当理解,除纤维素以外的纤维可被原纤化,以生产极细原纤,如合成纤维,尤其是丙烯酸或尼龙纤维,或其它天然纤维素材料。 It should be understood that fibers other than cellulose may be fibrillated to produce extremely fine fibrils, such as synthetic fibers, especially acrylic or nylon fibers, or other natural cellulosic materials. 可在微生物拦截增强过滤助剂中使用原纤化和非原纤化纤维的组合。 In a microbiological interception enhanced filter aid used fibrillated and non-fibrillated fiber combination.

微生物拦截增强剂用能在过滤助剂材料的表面上产生正电荷的微生物拦截增强剂来化学处理过滤助剂材料。 With a microbiological interception enhancing agent capable of producing a positive charge on the surface of the filter aid material to a microbiological interception enhancing agent chemically treated filter aid material. 化学处理在处理表面上产生强的正电荷,这使用流动或ξ电势分析来确定,和这一正电荷在低于10的pH值下得到保留。 Chemical treatment on the surface in the process of generating a strong positive charge, which the use of mobile or ξ potential analysis to determine, and this positive charge is retained at pH values less than 10. 阳离子材料可以是小的带电分子或在沿着聚合物链的长度方向上具有带正电荷的原子的直链或支链聚合物,其中所述聚合物链具有与其缔合的抗衡离子。 Cationic material may be a small charged molecule or a linear or branched polymer along the length of the polymer chain having a positively charged atom, wherein said polymer chains having associated therewith a counter ion. 阳离子材料吸附在过滤助剂材料的至少一部分上,和用与阳离子材料直接相邻的以及在至少一部分过滤助剂材料上的抗衡离子沉淀生物活性金属。 Cationic material adsorbed on at least a portion of a filter aid material, and the use of the cationic material is directly adjacent to and on at least a portion of a filter aid material precipitated bioactive metal counterion.

若阳离子材料是聚合物,则电荷密度优选大于约1个带电原子/约每30埃的分子长度,优选大于约1个带电原子/约每20埃分子长度,和更优选大于约1个带电原子/约每10埃分子长度。 If the cationic material is a polymer, the charge density is preferably greater than about 1 charged atom / molecule length about every 30 Angstroms, preferably greater than about 1 charged atom / molecule length per about 20 angstroms, and more preferably greater than about 1 charged atom / about 10 angstroms per molecule length. 在阳离子材料上的电荷密度越高,与其缔合的抗衡离子的浓度越高。 In the charge density on the cationic material, the higher the concentration of its associated counter ions. 可使用高浓度的合适抗衡离子以驱使生物活性金属的沉淀。 Suitable high concentration may be used to drive the counter ion of the bioactive metal precipitate. 阳离子材料的高电荷密度提供吸附和显著反转在制备微生物拦截增强过滤助剂中有用的原料的正常负电荷,阳离子材料不管在高或者在低pH环境下,应当始终给微生物拦截增强过滤助剂提供高度带正电的表面,这通过流动或ξ电势分析仪来确定。 High charge density cationic material adsorbed and provide significant reversal in the manufacture of a microbiological interception enhanced filter aid normal negative charge of useful materials, cationic materials regardless of high or low pH environment, it should always be to the microbiological interception enhanced filter aid provide highly positively charged surface, which is determined by the flow or ξ potential analyzer.

使用足够高分子量的阳离子聚合物使得在没有严重地附带影响过滤助剂材料如活性炭的中孔(mezo-pore)和微孔的任何吸附能力的情况下,可处理微生物拦截增强过滤助剂的表面。 A sufficient high molecular weight cationic polymer such that in the absence of serious collateral effects of a filter aid material such as activated carbon mesoporous (mezo-pore) and any of the adsorption capacity of the micropores, can handle a microbiological interception enhanced filter aid surface . 阳离子材料的分子量可大于或等于约5000道尔顿,优选大于或等于100000道尔顿,更优选大于或等于约400000道尔顿,和可大于或等于约5000000道尔顿。 Molecular weight cationic material may be greater than or equal to about 5,000 daltons, preferably greater than or equal to 100,000 daltons, more preferably greater than or equal to about 400,000 daltons, and may be greater than or equal to about 5,000,000 Daltons.

阳离子材料包括但不限于季铵化胺,季铵化酰胺,季铵盐,季铵化酰亚胺,苄烷铵化合物,双胍,阳离子氨基硅化合物,阳离子纤维素衍生物,阳离子淀粉,季铵化聚二醇胺缩合物,季铵化胶原多肽,阳离子甲壳质衍生物,阳离子瓜耳胶,胶体如阳离子蜜胺-甲醛酸胶体,无机处理过的硅石胶体,聚酰胺-表氯醇树脂,阳离子丙烯酰胺,聚合物和其共聚物,其组合和类似物。 Cationic materials include, but not limited to, quaternized amines, quaternized amides, quaternary ammonium salts, quaternized imides, benzalkonium compounds, biguanides, cationic amino silicone compounds, cationic cellulose derivatives, cationic starch, quaternary ammonium of polyglycol amine condensates, quaternized collagen polypeptides, cationic chitin derivatives, cationic guar gum, colloids such as cationic melamine - formaldehyde acid colloids, inorganic treated silica colloids, polyamide - epichlorohydrin resin, cationic acrylamide, polymers and copolymers thereof, combinations thereof and the like. 可用于该应用的带电分子可以是具有单个带电单元和能够连接到过滤助剂材料的至少一部分上的小分子。 Charged molecules can be used for this application may be a single unit and can be connected to the charged filter aid material is at least a portion of the small molecule. 阳离子材料优选具有一个或多个与其缔合的抗衡离子,在暴露于生物活性金属盐溶液时,使得靠近阳离子表面的金属优先沉淀以形成胶态金属沉淀络合物。 Cationic material preferably has one or more counter ions associated therewith, upon exposure to a biologically active metal salt solution, the so close to the surface of the metal cations preferentially precipitate to form colloidal metal precipitate complex.

例举的胺可以是吡咯,表氯醇衍生的胺,其聚合物和类似物。 Exemplary amines may be pyrroles, epichlorohydrin derived amines, polymers thereof, and the like. 例举的酰胺可以是公开于国际专利申请No.WO 01/07090的那些聚酰胺和类似物。 Exemplary amides may be those published application No.WO 01/07090 polyamide and the like in the international patent. 例举的季铵盐可以是二烯丙基二甲基卤化铵的均聚物,表氯醇衍生的聚季胺聚合物,衍生自二胺和二卤化物的季铵盐,例如公开于美国专利2,261,002,2,271,378,2,388,614,和2,454,547(在此将其作为参考引入本发明)和公开于国际专利申请No.WO 97/23594(也在此将其作为参考引入本发明)的那些,聚六亚甲基二甲基溴化铵和类似物。 Exemplary quaternary ammonium salts may be a diallyl dimethyl ammonium halide homopolymers, poly quaternary amine polymer epichlorohydrin derived, are derived from diamines and dihalides quaternary ammonium salts, such as disclosed in U.S. Patents 2,261,002,2,271,378,2,388,614, and 2,454,547 (herein incorporated by reference which present invention) and are disclosed in International Patent Application No.WO 97/23594 (also incorporated by reference herein in its present invention) that, polyhexamethylene dimethyl ammonium bromide and the like. 阳离子材料可化学键接、吸附、或交联至自身和/或至过滤助剂材料上。 Cationic material may chemically bonded, adsorbed, or crosslinked onto itself and / or to the filter aid material.

此外,适用作阳离子材料的其它材料包括得自BioShieldTechnologies,Inc.,Norcross,Georgia的BIOSHIELD。 Furthermore, other materials suitable for use as the cationic material comprises from BioShieldTechnologies, Inc., Norcross, Georgia of BIOSHIELD. BIOSHIELD是一种有机硅烷产品,包括约5%重量的十八烷基氨基二甲基三甲氧基甲硅烷基丙基氯化铵和低于3%的氯丙基三甲氧基硅烷。 BIOSHIELD is an organosilane product including approximately 5% by weight of octadecyl-amino-dimethyl-trimethoxysilyl propyl ammonium chloride and less than 3 percent chloropropyl trimethoxysilane. 可以使用的另一材料是SURFACINE,其得自Surfacine Development CompanyLLC,Tyngsboro,Massachusetts。 Another material that can be used is SURFACINE, which is derived from Surfacine Development CompanyLLC, Tyngsboro, Massachusetts. SURFACINE包含通过使聚(六亚甲基双胍)(PHMB)与4,4′-亚甲基-二-N,N-二缩水甘油苯胺(MBGDA)(交联剂)反应以将PHMB共价键接到聚合物表面上而得到的三维聚合物网状结构。 SURFACINE comprises by reacting a poly (hexamethylene biguanide) (PHMB) and 4,4'-methylene - bis -N, N- diglycidyl aniline (MBGDA) (crosslinking agent) reacted to covalently PHMB bonding to the polymer surface to give a three-dimensional polymer network structure. 碘化银形式的银被引入该网状结构,和作为亚微米尺寸的颗粒被截留。 Form of silver iodide is introduced into the network structure, and as submicron size particles are trapped. 该组合是一种可用于本发明的有效杀生物剂。 The compositions useful in the present invention is an effective biocide. 取决于过滤助剂材料,MBGDA可以或不将PHMB交联至微生物拦截增强过滤助剂上。 Depending on the filter aid material, MBGDA PHMB may or may not be cross-linked to the microbiological interception enhanced filter aids.

将阳离子材料暴露于生物活性金属盐溶液下,以便金属胶体络合物沉淀到至少一些过滤助剂材料的至少一部分表面上。 The cationic material is exposed to a biologically active metal salt solution, so that a metal colloid complex is precipitated onto the surface of at least a portion of at least some of the filter aid material. 为此,生物活性金属是优选的。 To this end, the bioactive metal is preferred. 这些生物活性金属包括但不限于银,铜,锌,镉,汞,锑,金,铝,铂,钯和其组合。 These bioactive metals including, but not limited to, silver, copper, zinc, cadmium, mercury, antimony, gold, aluminum, platinum, palladium, and combinations thereof. 最优选的生物活性金属是银和铜。 The most preferred biologically active metals are silver and copper. 优选选择生物活性金属盐溶液,使得阳离子材料中的金属和抗衡离子基本上不溶于含水环境以驱使金属络合物沉淀。 Biologically active metal salt solution is preferably selected such that the material of the metal cation and the counterion is substantially insoluble in an aqueous environment to drive precipitation of the metal complex. 优选地,金属的存在量是微生物拦截增强过滤助剂重量的约0.01%至约2.0%。 Preferably, the metal is present in an amount microbiological interception enhanced filter aid by weight of from about 0.01% to about 2.0%.

尤其有用的微生物拦截增强剂是银-胺-卤化物络合物。 A particularly useful microbiological interception enhancing agent is a silver - amine - halide complexes. 阳离子胺优选分子量为约400,000道尔顿的二烯丙基二甲基卤化铵的均聚物或具有类似电荷密度和分子量的其它季铵盐。 Cationic amine is preferably a molecular weight of about 400,000 daltons diallyl dimethyl ammonium halide homopolymer or other quaternary ammonium salts having a similar charge density and molecular weight. 可用于本发明的二烯丙基二甲基氯化铵的均聚物可以商品名MERQUAT100购自Nalco ChemicalCompany(Naperville,Illnois)。 Can be used in the present invention is diallyl dimethyl ammonium chloride homopolymer tradename MERQUAT100 available from Nalco ChemicalCompany (Naperville, Illnois). 氯抗衡离子可被替代为溴或碘抗衡离子。 Chlorine counterion can be replaced with a bromine or iodine counterion. 如果与硝酸银溶液接触,则银-胺-卤化物络合物沉淀在至少一部分微生物拦截增强过滤助剂上。 If contact with the silver nitrate solution, the silver - amine - halide complexes precipitate at least a portion of the microbiological interception enhanced filter aid.

活性炭常用作过滤助剂材料用于制备无色的麦芽饮料。 Activated carbon is often used as a filter aid material for the preparation of colorless malt beverage. 当微生物拦截增强过滤助剂包括活性炭时,阳离子材料优选具有高的电荷密度和足够高的分子量,以便产生对活性炭的带负电的表面基团的强烈吸引和高的配位能。 When microbiological interception enhanced filter aids include activated carbon, cationic material preferably has a high charge density and molecular weight high enough to produce activated carbon with a negatively charged surface groups with strong attraction and high potential energy. 同样,通过活性炭的疏水吸附机理,使用活性炭的带电表面补强了在生物活性金属胶体存在下的增强拦截。 Similarly, by hydrophobic adsorption mechanism of the activated carbon, the charged surface of the activated carbon used in reinforcing the interception enhanced biological activity of the presence of a metal colloid. 具有富氧化学的碳表面的未处理部分,倾向于具有负电荷,该负电荷可继续吸附带正电的颗粒。 The untreated portion has a carbon surface chemistry of oxygen-enriched, tend to have a negative charge, the negative charge can continue adsorbent particles positively charged. 正、负、和疏水表面的组合对于污染物的流过来说呈现出几乎不可逾越的阻挡。 Combination of positive, negative, and hydrophobic surface contaminants to flow over said showing a nearly insurmountable barrier.

在用微生物拦截增强剂处理过滤助剂材料之后,可使用X-射线荧光检测在活性颗粒上生物活性金属和其抗衡离子的存在。 After the filter aid material treated with a microbiological interception enhancing agent, X- ray fluorescence can be used to detect the presence of biological activity and its metal counter ion on the active particles.

制备微生物拦截增强过滤助剂的方法可用本领域熟练技术人员已知的工艺,包括喷涂、浸涂和类似方法,用微生物拦截增强剂处理可用于制备本发明微生物拦截增强过滤助剂的过滤助剂材料。 Preparation microbiological interception enhanced filter aid available methods known to those skilled in this art processes, including spray coating, dip coating, and the like, can be treated with a microbiological interception enhancing agent used in the preparation of the present invention is a microorganism interception enhanced filter aid filter aid materials. 以下概述了制备微生物拦截增强过滤助剂的例举方法,所述过滤助剂包括用微生物拦截增强剂处理的纳米纤维。 The following outlines the preparation method include a microbiological interception enhanced filter aid, the filter aid comprises a microbiological interception enhancing agent treated nanofibers. 粒状过滤助剂材料的类似处理工艺是本领域熟练技术人员已知的。 Granular filter aid material treatment process is similar to the skilled artisan.

在制备包括纳米纤维的微生物拦截增强过滤助剂中,将纤维丝束切断成特定的长度,通常在约1mm至约8mm范围内,和尤其在约3mm至约4mm范围内。 In the preparation of a microorganism comprising nanofiber reinforced intercepting filter aid, the tow was cut into a specific length, usually within the range from about 1mm to about 8mm, and within the range of from about 3mm to about 4mm in particular. 在具有类似于掺合器特征的设备内,或在较大规模上在常称为“hi-low”、“打浆机”或“匀浆机”的机器内,原纤化短切纤维。 In the apparatus having the characteristics similar blender, or on a larger scale is often called "hi-low", the "beater" or "refiner" machines, fibrillated chopped fiber. 使纤维经历反复的应力,同时进一步切断,并使纤维长度的下降最小。 The fibers undergo repeated stress, and further cut, and to decrease the minimum fiber length. 当纤维经历这些应力时,由于无定形和结晶区域之间的作用力弱导致纤维劈裂,和加拿大标准游离度(CSF)开始下降,其中所述加拿大标准游离度通过本领域公知的方法来测定。 When the fibers undergo these stresses, due to the amorphous and crystalline regions of the fibers lead to weak cleavage, and Canadian Standard Freeness (CSF) began to decrease, wherein the Canadian Standard Freeness by methods known in the art to determine . 可间隔地取出所得纸浆样品,和CSF可用作原纤化程度的间接量度。 The resulting pulp can be removed sample intervals, and the CSF used as an indirect measure of the degree of fibrillation. 尽管CSF值略微敏感于纤维长度,但它更强烈敏感于纤维的原纤化程度。 While the CSF value is slightly sensitive to the fiber length, but it is more strongly sensitive to the degree of fibrillation of the fibers. 因此,CSF是从纸浆中除水的容易程度的量度,它是监控纤维原纤化程度的合适方式。 Thus, CSF is a measure of the ease of removal of water from the pulp, it is suitable means to monitor the degree of fibrillation of fibers. 若表面积非常高,则在给定量的时间下非常少的水从纸浆中排出,和随着纤维更深入地原纤化,CSF值将逐渐变低。 If the surface area is very high, then in a given amount of time is very little water is drained from the pulp, and fibers with deeper fibrillated, CSF value gradually decreases. 一般地,对于本发明的应用来说,使用CSF低于100的纸浆,和优选CSF应当小于或等于约45。 Generally, for application of the invention, the use of less than 100 CSF pulp, CSF, and preferably should be less than or equal to about 45.

用阳离子材料处理纸浆,其方式使得阳离子材料涂布至少一些纤维的至少一部分表面,从而在纤维上赋予电荷。 Pulp treated with cationic material, in a manner such that the cationic material is applied at least a portion of at least some of the fibers of the surface, thereby imparting a charge to the fibers. 施加阳离子材料到纤维上的方法是本领域已知的,和包括但不限于喷涂、浸涂,或浸没涂布,以引起阳离子材料吸附、化学反应或交联到纤维表面上。 The method is applied to the fibers cationic materials are known in the art, and include, but are not limited to, spray coating, dip coating, or immersion coating, cationic materials to cause adsorption, chemical reaction or crosslinking to the fiber surface. 然后在反渗透/去离子水(RO/DI)水中漂洗已处理纸浆,通常在真空下部分脱水,产生预涂层,然后可将其暴露于生物活性金属盐溶液中。 Then the reverse osmosis / deionized water (RO / DI) water rinse treated pulp, usually partially dehydrated under vacuum, to produce a pre-coating, which can then be exposed to a biologically active metal salt solution. 使用几乎无离子的漂洗水引起与阳离子材料缔合的抗衡离子朝已处理的纤维表面紧密地吸引并排除了不想要的离子,所述不想要的离子可能引起生物活性金属不可控地沉淀到远离阳离子表面的位置上。 Use rinse water almost no ions cause material associated with the cationic counterion toward fiber surface treated tightly attract and eliminates unwanted ions, the ions may cause undesired bioactive metal uncontrollably precipitate away from the cation surface position.

使金属盐溶液渗透到纤维内,以使阳离子金属胶体络合物在至少一部分纤维表面上沉淀。 Metal salt solution penetration into the fiber, so that the cationic metal complex is precipitated colloid on at least a portion of the fiber surface. 该沉淀精确地沉积与阳离子涂层相邻的金属胶体,这是因为与该涂层缔合的抗衡离子同施加的金属盐反应形成胶体颗粒所致。 The precipitate was precisely deposited coating adjacent to the cationic metal colloid, which is reacted with the coating because the metal salt counterions associated with the formation of colloidal particles is applied due. 在充分暴露于生物活性金属盐溶液之后,可漂洗纤维并除去过量的水。 After sufficient exposure to biologically active metal salt solution, and the fibers can be rinsed to remove excess water. 当将硝酸银用作金属盐溶液时,可使用获自KratosAnalytical(日本的Shimadzu Group Company)的Kratos EDX-700/800X-射线荧光分光计,证明沉淀银的存在。 When silver nitrate is used as the metal salt solution, may be used obtained from KratosAnalytical (Japan Shimadzu Group Company) of Kratos EDX-700 / 800X--ray fluorescence spectrometer, prove the existence of precipitation of silver.

也可将颗粒、纤维、晶须或粉末形式的一种或多种添加剂与微生物拦截增强过滤助剂混合,以吸附其它污染物或参与微生物或其它污染物的拦截。 May be particles, fibers, whiskers, or powder form of one or more additives with the microbiological interception enhanced filter aid were mixed to adsorb other contaminants or participate in microorganisms or other contaminants to intercept. 有用的添加剂可包括但不限于金属颗粒,活化矾土,活性炭,二氧化硅,聚合物粉末和纤维,玻璃珠粒或纤维,纤维素纤维,离子交换树脂,工程树脂,陶瓷,沸石,硅藻土,活化铝土矿,漂白土,硫酸钙,其它吸附剂材料如超吸收性聚合物(SAP),或其组合。 Useful additives may include, but are not limited to, metallic particles, activated alumina, activated carbon, silica, polymeric powders and fibers, glass beads or fibers, cellulose fibers, ion-exchange resins, engineered resins, ceramics, zeolites, diatomaceous earth, activated bauxite, fuller's earth, calcium sulfate, other adsorbent materials, such as superabsorbent polymer (SAP), or a combination thereof. 也可根据特定应用化学处理添加剂,以赋予微生物拦截能力。 Can also be processed according to the specific application of chemical additives to impart microbiological interception capability. 这些添加剂优选以使得在用于过滤用途时所得预涂层组合物和/或滤饼中的流体流动基本上不受阻碍的充分量存在。 These additives are preferably such that the resulting pre-coating composition and / or the filter cake in an amount sufficient substantially unimpeded fluid flow when used in the presence of filtration applications. 添加剂的量取决于过滤体系的特定用途。 The amount of additive depends on the particular use of the filter system.

微生物拦截增强过滤助剂可以基于组合物重量为约0.5%至约50%的少量与主体过滤助剂混合,以增强本体过滤助剂的性能。 Microbiological interception enhanced filter aid can be mixed filter aid is from about 0.5% to about 50% based on the main body of a small amount of weight of the composition, to enhance the body filter aid performance.

在本发明的预涂层组合物中使用微生物拦截增强过滤助剂的方法使包括微生物拦截增强过滤助剂的流体形式的分散液经过支撑介质,如隔膜或滤网,和在支撑介质上形成厚度通常为约0.5至约3mm的预涂层。 Using the microbiological interception enhanced filter aid precoat composition method in the present invention comprises the dispersion of fluid in the form of a microbiological interception enhanced filter aid through a support medium, such as a membrane or filter, and having a thickness on the support medium typically from about 0.5 to about precoat of 3mm. 支撑介质具有的尺寸和平方英尺数使得待过滤的流体的流速没有慢到使大规模的制备工艺受到限制。 The size and number of square feet to support medium has to be filtered so that the flow rate of the fluid is not slow to make large-scale preparation process is limited. 待过滤的流体经过滤饼和粒状微生物污染物截留在滤饼上。 Fluid to be filtered through the filter cake and microbiological contaminants trapped on the particulate cake. 在流体过滤经过滤饼之前,可包括微生物拦截增强过滤助剂的主体原料组合物可与流体混合。 Before filtering the fluid through the filter cake, may comprise a microbiological interception enhanced filter aid body raw material composition may be mixed with the fluid. 添加主体原料组合物促进了(open up)滤饼的渗透性和防止在滤饼上形成截留污染物的不可渗透网。 Adding the main raw material composition promoted (open up) the cake permeability and prevent the formation of pollutants trapped in the filter cake impermeable net. 当终止过滤时,反冲刷滤饼和滤饼脱离支撑介质。 Upon the termination of filtering, anti-erosion and filter cake from the cake support media. 已用过的滤饼作为饼或浆料被弃置。 Has been used as a pie or cake slurry being dumped.

包括微生物拦截增强过滤助剂的预涂层组合物可提供微生物污染物(包括病毒)至少约3的对数下降,从而提供单步冷冻灭菌技术。 Including microbiological interception enhanced filter aid precoat composition may provide microbial contaminants (including viruses) of at least about 3 log reduction, thereby providing a single-step freezing sterilization techniques. 若不需要这种全面拦截,则可将微生物拦截增强过滤助剂以基于预涂层组合物重量为约0.5%至约50%的量与不带电的主体过滤助剂混合,以提供所需程度的拦截。 If required this comprehensive intercept, can be a microbiological interception enhanced filter aid precoat composition based on the weight of the filter aid mixing from about 0.5% to about 50% by weight and uncharged body, to provide the desired degree interception.

实施例提供以下实施例说明本发明,而不应理解为限定本发明的范围。 Example The following examples illustrate the present invention and are not to be construed as limiting the scope of the invention.

使用American Type Culture Collection(ATCC)No.11775的大肠杆菌(Escherichia coli)的悬浮液,进行过滤助剂的细菌挑战,以评估对细菌挑战的响应。 Using the American Type Culture Collection (ATCC) No.11775 E. coli (Escherichia coli) suspension, bacterial challenge filter aid, to assess the response to bacterial challenge. 使用ATCC的标准操作步骤繁殖细菌,并使用本领域熟知的标准微生物步骤制备和量化受到细菌悬浮液挑战的过滤助剂的流入液和流出液中的细菌。 ATCC standard procedures using the growth of bacteria, and known in the art using standard microbiological step of preparing a filter aid and the quantization by the challenge of the bacterial suspension flows into the liquid and the effluent bacteria.

在下述实施例中使用的预涂布表面的直径为47mm和在获自Fischer Scientific,Pittsburgh,Pennsylvania的Osmonics/MSIGRAVI-SEALTM分析漏斗上形成该预涂布表面。 Pre-coating surface diameter used in Examples In the following examples for the pre-coating is formed on the surface of 47mm and Osmonics obtained from Fischer Scientific, Pittsburgh, Pennsylvania's / MSIGRAVI-SEALTM analysis funnel. 用以商品名REEMAYTM2004商购于BBA Nonwovens Reemay,Inc.(Old Hickory,Tennessee)的纺粘聚酯做分析漏斗的衬里。 Tradename REEMAYTM2004 for commercially available from BBA Nonwovens Reemay, Inc. (Old Hickory, Tennessee) spunbond polyester lining funnel for analysis.

实施例1(比较):未处理纤维素对E.coli的拦截在分析漏斗内,将获自International Fiber Corporation、干重为约0.63g的Alpha-Cel BH-40纤维素纸浆形成为预涂层。 Example 1 (comparative) Example: An unhandled cellulose E.coli interception in the analysis of the funnel, obtained from the International Fiber Corporation, a dry weight of about 0.63g of Alpha-Cel BH-40 cellulose pulp is formed as a pre-coating . 使用蠕动泵,使RO/DI水流过预涂层,以实现31ml/min的流量。 Using a peristaltic pump, so that RO / DI water flows through the precoat layer, in order to achieve 31ml / min flow rate. 用含有1.06105E.coli的细菌悬浮液挑战预涂层。 Bacterial suspension containing 1.06 105E.coli challenge precoat. 含未处理纤维素纸浆的预涂层的对数下降值小于约1。 The number of unprocessed cellulosic pulp containing precoat drop value is less than about 1.

实施例2(比较):在与5%未处理Lyocell纳米纤维混合的未处理纤维素上E.coli的拦截在350ml RO/DI水中,使用与干重为0.03g的未处理原纤化Lyocell纤维混合的干重为0.60g的BH-40纤维素纸浆,制备预涂层。 And 5% in the untreated Lyocell cellulose nano-hybrid fiber untreated E.coli interception in 350ml RO / DI water, and the dry weight of 0.03g use untreated fibrillation Lyocell fiber: Example 2 (comparative) Implementation mixing the dry weight of 0.60g of BH-40 cellulose pulp, prepared precoat layer. 使用蠕动泵,使RO/DI水以约80ml/min的流量流过预涂层。 Using a peristaltic pump, so that RO / DI water at about 80ml / min of flow through the precoat layer. 用含有1.06105E.coli的细菌悬浮液挑战预涂层。 Bacterial suspension containing 1.06 105E.coli challenge precoat. 预涂层的对数下降值小于约1。 Logarithmic precoat drop value is less than about 1.

实施例3(比较):与5%过滤助剂混合的未处理纤维素的E.col拦截,其中所述过滤助剂用经阳离子材料处理的Lyocell纤维制备将用量为干重约11.4g(120.0g湿重)、加拿大标准游离度为45的原纤化Lyocell纳米纤维分散在含有3.0ml MERQUAT100(30%的水溶液)和0.27g溴化钠的1.0L RO/DI水中过夜。 Example 3 (Comparative): E.col mixed with 5% of untreated cellulose filter aid interception, wherein said filter aid material is produced from fibers treated Lyocell cation will be an amount of the dry weight of about 11.4g (120.0 g wet weight), a Canadian Standard Freeness of 45 nano-fibrillated Lyocell fiber dispersion containing 3.0ml MERQUAT100 (30% solution in water) and 0.27g of sodium bromide 1.0L RO / DI water overnight. 将所得带电纤维倾倒入配有100目成形丝网的标准8英寸Brit过滤器中,并在真空下除去过量水,从而形成纸片。 The resulting charged fibers was poured into 100 mesh forming wire with a standard 8 inches Brit filter, and excess water removed under vacuum to form a paper sheet. 用500ml RO/DI水漂洗纸片。 With 500ml RO / DI water rinse paper.

使用与干重为0.03g带电原纤化Lyocell纤维混合的干重为0.60gBH-40纤维素纸浆制备预涂层。 Use charged with 0.03g dry weight fibrillated Lyocell fiber mixed dry weight 0.60gBH-40 cellulose pulp prepared precoat layer. 使用蠕动泵,使RO/DI水以约28ml/min的流量流过预涂层。 Using a peristaltic pump, so that RO / DI water at about 28ml / min of flow through the precoat layer. 用含有1.06105E.coli的细菌悬浮液挑战预涂层。 Bacterial suspension containing 1.06 105E.coli challenge precoat. 预涂层的对数下降值为约2.10。 Logarithmic precoat drop value of about 2.10.

实施例4:用与微生物拦截增强过滤助剂混合的未处理纤维素对E.coli的拦截将用量为干重约11.4g(120.0g湿重)、加拿大标准游离度为45的原纤化Lyocell纳米纤维分散在含有3.0ml MERQUAT100(30%的水溶液)和0.27g溴化钠的1.0L RO/DI水中过夜。 Example 4: By a microbiological interception enhanced filter aid mixing of untreated cellulose E.coli intercept the amount of dry weight of about 11.4g (120.0g wet weight), a Canadian Standard Freeness of the fibrillated Lyocell 45 nanofiber dispersion containing 3.0ml MERQUAT100 (30% solution in water) and 0.27g of sodium bromide 1.0L RO / DI water overnight. 将所得带电纤维倾倒入配有100目成形丝网的标准8英寸Brit广口瓶中,并在真空下除去过量水,从而形成纸片。 The resulting charged fibers was poured into 100 mesh forming wire with a standard 8 inches Brit jar, and the excess water removed in vacuo to form a paper sheet. 用500ml RO/DI水漂洗纸片。 With 500ml RO / DI water rinse paper. 通过添加60ml RO/DI水稀释稀硝酸银溶液,一种3.0ml的储液(在60ml RO/DI水内的1.8g AgNO3),并均匀倾倒在纸片上,以提供充分的暴露和饱和度。 DI water was diluted by the addition of 60ml RO / dilute silver nitrate solution A 3.0ml of stock solution (in 60ml RO / DI water, 1.8g AgNO3), and uniformly poured onto a paper sheet, to provide adequate exposure and saturation. 使硝酸银溶液在纸片上静置至少约15分钟和在真空压力下除去过量水,得到本发明的微生物拦截增强过滤助剂。 Silver nitrate solution was allowed to stand on the paper sheet at least about 15 minutes and the excess water removed under vacuum pressure, to obtain microorganisms of the invention interception enhanced filter aid.

使用与干重为0.03g的微生物拦截增强过滤助剂混合的干重为0.60g的未处理BH-40纤维素纸浆,制备预涂层。 Use with 0.03g dry weight of microbiological interception enhanced filter aid mixing 0.60g dry weight of untreated cellulosic pulp BH-40, prepared precoat layer. 使用蠕动泵,使RO/DI水以约31ml/min的流量流过预涂层。 Using a peristaltic pump, so that RO / DI water at about 31ml / min of flow through the precoat layer. 用含有1.06105E.coli的细菌悬浮液挑战预涂层。 Bacterial suspension containing 1.06 105E.coli challenge precoat. 该预涂层的对数下降值为约5.02,这表明E.coli完全除去。 The precoat logarithmic decline value of about 5.02, suggesting that E.coli completely removed.

实施例5:微生物拦截增强过滤助剂对E.coli的拦截使用蠕动泵,使RO/DI水以约28ml/min的流量流过实施例4所述的干重为0.63g的微生物拦截增强过滤助剂的预涂层。 Example 5: microbiological interception enhanced filter aid of E.coli interception using a peristaltic pump, so that RO / DI water at about 28ml / min of the flow rate through the dry weight of Example 4 according to embodiments of the microbiological interception enhanced filter 0.63g Pre-coating additives. 用含有1.0104E.coli的细菌悬浮液挑战预涂层。 Bacterial suspension containing 1.0 104E.coli challenge precoat. 微生物拦截增强过滤助剂的对数下降值为4.00,这表明E.oli完全除去。 Logarithm of the microbiological interception enhanced filter aid decreased value 4.00, which indicates E.oli completely removed.

下表I示出了实施例1-5的结果。 Table I shows the results of Examples 1-5.

表I实施例1-5中E.coli的对数下降值 Table 1-5 log reduction in E.coli of Example I embodiment

MIEFA=本发明的微生物拦截增强过滤助剂CFU=每块板上的菌落形成单位。 Microorganism of the present invention MIEFA = interception enhanced filter aid CFU = colony forming units per board.

如实施例4所示,添加甚至少量的本发明微生物拦截增强过滤助剂看上去提供预涂层组合物显著的微生物拦截能力用于降低E.coli。 As shown in Example 4, adding even a small amount of the microorganisms of the present invention appears to provide interception enhanced filter aid precoat composition significant microbiological interception capability for reducing E.coli. 仅仅包括所述微生物拦截增强过滤助剂的实施例5的预涂层组合物提供优良的细菌拦截。 Includes only the microbiological interception enhanced filter aid precoat composition of Example 5 to provide excellent bacteria interception.

尽管已结合特定优选的实施方案具体描述了本发明,但显然根据上文描述,许多替换、修改和变化对本领域熟练技术人员来说是显而易见的。 Although already in connection with specific preferred embodiments of the present invention is specifically described, according to the above description it will be apparent that many alternatives, modifications and variations of the skilled artisan is obvious. 因此认为,所附权利要求书包括落入本发明真实范围和主旨内的任何这些替换、修改和变化。 Therefore considered, including the appended claims fall within the true scope and spirit of the present invention, any such alternatives, modifications and variations.

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CN104302378B *13 Dec 20123 May 20173M创新有限公司包含含金属颗粒的过滤介质
CN104321348A *7 Mar 201328 Jan 2015Dic株式会社Modified cellulose nanofiber and resin composition including modified cellulose nanofiber
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Classifications
International ClassificationC02F1/44, B01D71/06, B01D39/16, B01D29/15, C02F1/28, C02F1/00, C02F1/42, C12H1/044, B01D39/20, C02F1/76, B01J20/32, B01J20/28, F24F3/16, B01J20/26, B01D39/04, A01N25/26, B01J20/24, B01D39/06, C02F1/50, B01D37/02, A61L9/16, B01D39/18, A61L2/00, C12H1/056, A61L2/02
Cooperative ClassificationB01J20/3236, B01J20/3212, B01J20/3293, B01J20/3204, C02F1/283, B01J20/28014, Y10T428/249982, A61L9/16, B01D39/18, C02F1/004, C02F1/505, C12H1/0408, B01D2201/34, B01J20/28023, B01D29/15, C02F1/42, C02F1/281, A61L2/0017, C02F2303/04, C02F1/001, B01D37/02, C02F2307/04, B01D39/1623, C02F1/003, C12H1/0424, C02F1/444, C02F1/76, B82Y30/00, A61L2/0082, Y10T428/249978, B01J2220/42, B01D39/2017, Y10T428/249967, B01J20/28007, A61L2/022
European ClassificationB01J20/28D8, B01J20/28D, B01J20/28B4D, C02F1/00D6, B01D29/15, B01J20/32D4D, B82Y30/00, C02F1/50B, B01D37/02, B01J20/32, C02F1/44D, A61L2/02F, A61L9/16, B01D39/18, B01D39/16B4, C02F1/00D4, C12H1/04C4, B01D39/20B4, A61L2/00P4, C12H1/04B, A61L2/00P2A
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