CN1235849A - Automatic hemodialysis filter - Google Patents

Automatic hemodialysis filter Download PDF

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Publication number
CN1235849A
CN1235849A CN 98112254 CN98112254A CN1235849A CN 1235849 A CN1235849 A CN 1235849A CN 98112254 CN98112254 CN 98112254 CN 98112254 A CN98112254 A CN 98112254A CN 1235849 A CN1235849 A CN 1235849A
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dialysis
computer
dialysis solution
filter
pump
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彭罗民
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Abstract

Automatic hemodialysis filter consists of extracorporeal blood circulation system, dialysate circulation, volume and temperature monitoring system and dialysis filtering and monitoring system. It is suitable for treating and curing acute and chronic kidney hypofunction, uraemia, drug poisoning and herion poisoning. The extracorporeal blood circulation is that the roller pump drives blood from arterial duct to flow through hemodialysis filter and vein duct, and return to body of the patient. The dialysate circulation is that the dialysate pump drives dialysate from dialysate container to flow through dialysate pipe and hemodialysis filter and return to dialysate container; and the other dialysate circulation is realized by the lift to drive the dialysate bag to move like a cable car.

Description

Automatic hemodialysis filter
The present invention relates to a kind of armarium, particularly a kind of automatic hemodialysis filter.The present invention is fit to medical institutions at different levels and is used to give treatment to acute renal failure, chronic renal failure, uremia, multiple organ dysfunction syndrome companion renal failure, medicine (sedative hypnotics, psychosis, rat poison etc.) is poisoned, toxic poisoning, heroin poisoning, addiction are spilt smart the poisoning, nephrotic syndrome is accompanied serious fluid retention, and diabetic nephropathy is accompanied serious fluid retention etc.
The common advantage of conventional hemodialysis (CHD) machine of prior art is: 1, can do hydrocarbonate dialysis; 2, the capacity monitor system is arranged; 3, rely on computer control.Conventional hemo system all has common shortcoming to be: 1, cost an arm and a leg, the conventional hemodialysis (CHD) machine price that generally has hydrocarbonate dialysis and capacity monitor is all ten thousand/every of 30-40.Every main frame of paired filtration dialysis machine adds water treatment machine needs nearly 500,000 yuan.The paired filtration dialysis device is by a small-sized polysulfone membrane filter (filter area: 0.55m 2) and a fiber-like dialyser (dialyser area: 1.15-1.60m 2) the butt joint formation.Paired filtration dialysis device main frame is except that the device the same with conventional hemo system, main progress is: (1) has increased urea sensor on the filtered solution flowline, so that the concentration of carbamide in the monitoring of blood filtered solution in treatment helps adjusting definite treatment time monitoring state of an illness; (2) being provided with activated carbon adsorption on the filtered solution flowline irritates, make filtered solution urotoxins such as the creatinine in the removing filtered solution, uric acid when irritating by absorption, after filtered solution leaches from filter, filtered solution is introduced in the blood circulation of the dialyser that docks the below by the filtered solution drainage catheter, filtered solution is reclaimed, reduce amount infused.[A.Santoro0n-line monitoring Nephrology Dialysis Transplantation 1995.10.615-618]; [L.J.Garred, B.Canaud, J.Y.Bosc and C.Tetta Urea rebound deliverdKt/V determination with acontinuous urea sensor]; [P.M.GhezziHemodiafiltration with Separate Convection and Diffusion:PairdFiltration Dialysis Contr.Nephro., vol.69, pp.141-161,1989] especially charcoal tube technical difficulty is also little in this design, but improved the treatment cost, made general middle and small hospital be difficult to make inquiries this type of expensive conventional hemodialysis (CHD) machine.2, in a single day rely on the water source, the haemodialysis control unit of conventional import or domestic assembling all relies on the water source, cuts off the water in the treatment, must stop treatment, to prevent adverse consequences.3, to using the environmental requirement height, can not be used to the rescue of paying a home visit.4, to the power requirement height, voltage is low slightly can to break down, and can not treat.5, the maintenance difficult that breaks down, medical personnel can't keep in repair.6, big to water consumption, each treatment needs can finish seance more than 120,000 milliliters.7, the dialysis solution liquid-supplying system is very complicated, and the chance that breaks down is also along with increase.
A kind of domestic at present, the new type auto hemodialysis filter that abroad do not have that the objective of the invention is to design at the deficiency of existing conventional hemodialysis (CHD) machine and new automatic working procedure thereof, she is fit to China's national conditions of present stage, can use in all medical institutions.The present invention can be used as blood dialysis ultrafiltration, hemodiafiltration, and pairing hemofiltration dialysis, pure hemofiltration, simple blood ultrafiltration, hemoperfusion, plasmapheresis, blood dialysis ultrafiltration and perfusion carry out etc. simultaneously.Be mainly used in the treatment acute renal failure, chronic kidney hypofunction, early stage, late period, whole latter stage uremia, the multiple organ failure, MOF accompanies the kidney sorrow, drug intoxication, toxic poisoning, heroin poisoning, addiction etc.
The present invention is achieved in that it is by extracorporeal blood circulation system; Dialysis solution circulation, dialysis solution capacity, dialysate temperature monitoring system; Dialysis filtration system and computer automatic monitoring system constitute.The invention is characterized in:
A. dialysis solution circulation, the dialysis solution capacity, the dialysate temperature monitoring system is to be connected and to be imported dialysis solution to (3) by the heat junction block (2-1) of thermostat (3) of dialysis solution circulation outlet tube (1) and dialysis solution, dialysis solution is warm through the weighing apparatus of heating in dialysis solution is heated thermostat (3), export dialysis solution circulation pipe (4) to from heat another junction block (2-2) of thermostat (3) of dialysis solution, and and dialyser, the dialysis-type dialysis filter, the dialysate hole of dialysis filter or filter or paired filtration dialysis device (5) one ends is connected, dialysis solution is from dialyser, the dialysis-type dialysis filter, after the dialysate hole of dialysis filter or filter or paired filtration dialysis device (5) other end is discharged, be connected with dialysis solution circulation pipe (4), dialysis solution circulation pipe (4) moves ahead and is connected with dialysis solution pump line (6), carbamide biosensor (6-1) is arranged on the pipeline of dialysis solution circulation pipe (6), driving through dialysis liquid pump (7), attract dialysis solution to continue to proceed to dialysis solution circulation input pipe (8), dialysis solution circulation outlet tube (1) and dialysis solution circulation input pipe (8) are all inserted in the dialysis fluid container (9), dialysis fluid container (10) is standby continued access dialysis solution, dialysis fluid container (9,10) being placed on electronics weight weighing apparatus surveys on the device pressure sensing applicator platform (11), the below of surveying device pressure sensing applicator platform (11) at electronics weight weighing apparatus is pressure transducer (12) and electric transmission system (13), electric transmission system (13) surveys the dialysis fluid container (9 that device pressure transducer (12) is surveyed to electronics weight weighing apparatus, 10) information bidirectional transfers to computer (37), accept the also instruction of object computer (37), constitute the dialysis solution circulation, dialysis solution capacity and dialysate temperature face the control system, as Fig. 1, shown in Figure 2.
B. extracorporeal blood circulation system is by ductus arteriosus (14), transfusion short tube (15) is connected with ductus arteriosus (14), blood pump pipe (16) is connected with ductus arteriosus (14), blood pump pipe (16) is housed in blood pump (17), appending calparine pipe (18) is connected with ductus arteriosus (14), heparin syringe (19) with append calparine pipe (18) and be connected, the other end and the dialyser of ductus arteriosus (14), the dialysis-type dialysis filter, the arterial end of dialysis filter or filter or paired filtration dialysis device (5) is connected, dialyser, the dialysis-type dialysis filter, the vein end of dialysis filter or filter or paired filtration dialysis device (5) is connected with venous duct (20), coupled bubble trap (21) is arranged on venous duct, exhaustor (22) and vein pressure pipe (23) are arranged on bubble trap (21), vein pressure pipe (23) is connected with venous pressure monitor and joint (24) under application state, the automatic vascular clamp (25) that venous duct (20) after the bubble trap is walked around air monitor continues to move ahead, on venous duct (20), there is blood sampling perforator (26) to constitute extracorporeal blood circulation system, as shown in Figure 1.
C. the dialysis filtration system is by paired filtration dialysis device (5), what link to each other with pairing dialysis filter (5) filtered solution tap is filtered solution collecting pipe (27), filtered solution collecting pipe (27) is connected with filtered solution collecting bag (28), and capacity monitor pick off hook (29) that links to each other with filtered solution collecting bag (28) and capacity monitor pick off (30) constitute the filtration fraction of dialysis filtration system; By balance liquid bag and tube for transfusion (31), tube for transfusion is lacked (15) with the transfusion on the ductus arteriosus and is connected, the balance liquid bag links to each other with capacity monitor pick off hook (32) with tube for transfusion (31) and capacity monitor pick off (the fluid infusion part of (33) formation dialysis filtration system; The electric transmission system (30-1 and 33-1) of capacity monitor pick off (30) and capacity monitor pick off (33) links to each other with computer cable line socket (37-1), constitutes the dialysis filtration system jointly, and is as Fig. 2, shown in Figure 3.
D. computer supervisory control system is by the extracorporeal circulation of blood monitoring system, dialysis solution circularly monitoring system, and the dialysate temperature monitoring, filtration, ultrafiltration, amount infused monitoring filter the monitoring of ultrafiltrate urea concentration, and system monitoring six parts constitute.
The extracorporeal blood circulation system monitoring is by starting power supply (34), be communicated with blood pump (17) energising, the rotating speed that can show blood pump after blood pump (17) starts at blood pump display screen (35), flow, and but the root a tree name need be adjusted rotating speed and flow at the adjusting knob (17-1) of blood pump (17), the height of venous pressure monitor (24) continuous monitoring static pressure, low, when venous pressure is too high or too low when meeting or exceeding threshold values, computer (37) instruction is reported to the police immediately, instruct blood pump (17) stall simultaneously, after getting rid of the venous pressure abnormal conditions, blood pump (17) can recover to rotate, proceed treatment, when entering air, bubble trap (21) reaches the critical horizontal plane, gas monitor sonac (36) is found out immediately, information is imported into computer (37), computer (37) immediate instruction blood pump (17) stall, instruct automatic vascular clamp (25) the clamp venous duct (20) of air monitor simultaneously, prevent that gas from entering in patient's body, when getting rid of bubble from exhaustor (22), blood pump (17) can recover to rotate, proceed treatment, as Fig. 3, shown in Figure 5.
Dialysis solution circulation, dialysate temperature, ultrafiltration and filtration fluid infusion monitoring system are by after starting power supply (34) startup, be communicated with dialysis liquid pump (7) energising, can show rotating speed, flow at dialysis liquid pump display screen (38) after dialysis liquid pump (7) starts, but and the root a tree name need adjust rotating speed and flow at the adjusting knob (7-1) of dialysis liquid pump (7); On the screen of computer (37), show simultaneously dialysate temperature ℃; In the time of on dialysis fluid container (9,10) being placed on weighing apparatus measuring device pressure sensing applicator platform (11), pressure transducer (12) promptly imports information into computer (37), and computer (37) is promptly continuously calculated the dialysis liquid measure and shown with the milliliter digital display; Treatment beginning computer (37) promptly writes down treatment time automatically, and with minute calculating, the dialysis solution total amount used in record simultaneously, ultrafiltration volume in the unit interval, ultrafiltration total amount, filtration total amount; Do you judge that by continuous calculating of computer (37) ultrafiltration volume, filtrable volume exceed standard? if ultrafiltration volume meets or exceeds the milliliter number of desired indicator, promptly show the milliliter number of answering the fluid infusion total amount on computer (37) screen automatically, and alarm needs the milliliter number of actual amount infused; If it is low or too high that dialysate temperature is crossed, be below or above predetermined temperature value, computer (37) is reported to the police immediately, dialysis liquid pump (7) can not start or stall, and when dialysate temperature recovers normal, dialysis liquid pump (7) can start or recover rotation, proceed treatment, as Fig. 3, shown in Figure 5.
Circulate another monitoring system and fluid infusion system of dialysis solution is to be carried out under the monitoring of computer (37) by elevator (39), start power supply, elevator (39) energising, when No. 1 full liquid bag being hung over high bit capacity monitor hook (32) and No. 2 empty liquid bags is hung over low bit capacity monitor pick off hook (29) and go up, computer (37) is promptly measured the milliliter number of No. 1 fresh dialysis fluid amount automatically, dialysis solution is from No. 1 high-order liquid bag, flow into dialyser (5), flow out dialyser (5), flow into low level liquid bag No. 2, does computer (37) judge that No. 1 liquid bag flows sky? if, elevator (39) affects chain (42) by reversible electric machine (40) transmitting gear (41), affects the sliding wheel (43-1) that draws by chain (42) again, (43-2), the offside of chain is that stainless steel wire rope (44) draws the sliding wheel (43-1 that draws from the negative; 43-2), with the stable sliding wheel (43-1 that draws; 43-2), automatically along clockwise upset exchange 1, the position of No. 2 liquid bags (weight sensor 33 and 30), the number of times of record exchange simultaneously 1 time, show dialysate flow, fluid volume adds up, each ultrafiltration volume, the ultrafiltration total amount, filter total amount and answer amount infused, if ultrafiltration volume is or/and filtrable volume surpasses predetermined target value, computer (37) is reported to the police automatically and is shown the milliliter number of answering the fluid infusion total amount on screen, and the liquid (31) that need are replenished hangs on the capacity monitor pressure transducer hook (32), and tube for transfusion is connected with transfusion short tube (15) on the ductus arteriosus (14) and carries out fluid infusion, computer (37) is counted real amount infused, are the real amount infused of continuous monitoring, computer (37) judged predetermined inferior the counting to not that exchange? if be less than, continue the upset exchange, if arrive, stop upset, notify from a phone call and change fresh dialysis fluid, if having a power failure suddenly, computer (37) is reported to the police automatically, notify from a phone call artificial exchange dialysis solution, treatment time arrives, and the order fulfillment treatment is as Fig. 2, Fig. 3, with shown in Figure 5.
Filtered solution, the urea concentration monitoring system is to be finished by carbamide biosensor (6-1) and computer (37) in the ultrafiltrate, when in needs monitorings filtered solution and/or the ultrafiltrate during urea concentration, can temporarily propose dialysis solution circulation outlet tube (1) to dialysis fluid container (9,10) outside, or with clamp clamps dialysis solution circulation outlet tube (1), at this moment, dialysis solution flows out to be ended, have only filtered solution and/or ultrafiltrate to flow out to carbamide biosensor (6-1) by dialysis solution circulation pipe (6), carbamide biosensor (6-1) reaches computer (37) to the information of being monitored, computer (37) demonstrates the concentration of carbamide in filtered solution and/or the ultrafiltrate as calculated, provide the dynamic experiment foundation as definite further treatment time and monitoring change of illness state, as shown in Figure 4.
The system monitoring system is by starting power supply by computer (37), be communicated with dialysis liquid pump (7), blood pump (17), elevator (39), Jian Kong three systems simultaneously, extracorporeal blood circulation system is monitored venous pressure high and low by venous pressure monitor and joint (24) transmission information to computer (37) by ultrasonic detector key monitoring bubble trap (21); The monitoring of dialysis solution blood circulation has two, and 1 is the blood circulation that dialysis liquid pump (7) drives, and arrives computer by pressure transducer (12) and the thermostat of heating (3) transmission information, the key monitoring dialysate temperature, ultrafiltration volume, filtrable volume needs amount infused and real amount infused; Another system is the dialysis solution blood circulation that is driven by elevator, key monitoring ultrafiltration volume, filtrable volume, need amount infused and real amount infused, as shown in Figure 5.
The complete machine of automatic hemodialysis filter is characterised in that: complete machine has adnexa infusion support (45), and chassis (46), chassis (46) are connected with automatic control frame (47), and automatic control frame (47) is connected mutually with complete machine steering wheel (48), as shown in Figure 3.The dialysis solution thermostat (3) of heating is by external device (ED) (49), and dialysis solution circulation pipe (50), heating member (51) and switch are regulated heating-up temperature display part (52) and constituted; Employing is to the method for the weighing apparatus temperature of heating indirectly by the dialysis solution in the dialysis solution circulation pipe in the thermostat of heating (3) the weighing apparatus temperature of heating, outside the dialysis solution circulation pipe in the thermostat of heating (3), the having heaters and the warm WATER AS FLOW MEDIUM of weighing apparatus of heating, the dialysis solution circulation pipe is immersed in the WATER AS FLOW MEDIUM of the thermostat of heating, both can reach the weighing apparatus temperature of heating, can keep the dialysis solution intraluminal cleaning that circulates again, under the situation of not treating, regularly WATER AS FLOW MEDIUM is warmed to 98 ℃, can reach the purpose of sterilization, make the dialysis solution circulation pipe intracavity in the thermostat of heating keep aseptic environments, as shown in Figure 4.
The present invention can also be achieved in that the dialysis solution liquid-supplying system is to be made of dialysis liquid pump (7) and elevator (39) two cover liquid-supplying systems, under the situation that electricity is arranged, both available dialysis liquid pump (7) liquid-supplying system, also available elevator (39) dialysis solution blood circulation, under situation about having a power failure, can utilize the liquid bag hook (29 and 32) of elevator (39) to carry out manual operations, continue to keep treatment, as shown in Figure 1.
The present invention can also be achieved in that automatic hemodialysis filter, it is characterized in that the automatic control part (comprising: computer (37), blood pump (17), dialysis liquid pump (7), venous pressure monitor (24), the gas monitor pick off (36) that rises to the Western Paradise, the thermostat of heating (3)) with the method manufacturing installation of automatic control frame (47) and elevator (39) with the split assembling; The automatic control part can be separated use separately with elevator (39), also can fit together in indoor use, as Figure 1-1.
The present invention can also be achieved in that its feature of automatic hemodialysis filter is that also dialysis fluid container (9,10) can be a macromolecular material, non-toxic polyvinyl chloride, polypropylene plastics, Merlon etc., also can be stainless steel material, the capacity of dialysis fluid container (9,10) be one of one of 3500ml and 5500ml.The shape of dialysis fluid container can be long cube, also can be other shape.Filtered solution collecting bag (28) and transfusion bag (31) can be macromolecular materials, also can be vials, and capacity is 500ml, 1000ml, 1500ml, one of 2000ml.Filtered solution collecting pipe (27) and liquid supplementation pipe (31) can be macromolecular materials, comprising: plastics, medical grade silicon rubber or medical latex tube are shown in Fig. 1-4.
The present invention can also be achieved in that its feature of automatic hemodialysis filter liquid pump (7) that also is to dialyse can be roller (pearl) pump, also can be centrifugal pump, can also be gear pump or vane pump, shown in Fig. 1-4.
Feature of the present invention also is: filtered solution, ultrafiltrate urea concentration monitoring system is to be finished by carbamide biosensor (6-1) and computer (37), when need detect the urea concentration of filtered solution and/or ultrafiltrate, temporarily dialysis fluid container (9 is proposed dialysis solution circulation outlet tube (1), 10) outside, or with clamp clamps dialysis solution circulation outlet tube (1), dialysis solution flowed out and ended this moment, have only filtered solution and/or ultrafiltrate to flow out to carbamide biosensor (6-1) by dialysis solution circulation pipe (6), the biological device (6-1) that passes of carbamide reaches computer (37) to the information of being monitored, computer (37) as calculated and demonstrate the concentration of carbamide in filtered solution and/or the ultrafiltrate provides the dynamic experiment foundation for further determining the treatment time and the monitoring state of an illness.
Below in conjunction with accompanying drawing this utility model is further described:
1-dialysis solution circulation outlet tube among Fig. 1 and the 2-dialysis solution thermostat junction block of heating combines and imports dialysis solution to the 3-dialysis solution thermostat of heating, the dialysis solution of weighing apparatus after the temperature heated another junction block output dialysis solution of thermostat to 4-dialysis solution circulation pipe from the 2-dialysis solution through heating, and with the 5-dialyser, the dialysis-type dialysis filter, the dialysate hole of dialysis filter or filter or paired filtration dialysis device one end combines, dialysis solution is from the 5-dialyser, the dialysis-type dialysis filter, after the other end dialysate hole of dialysis filter or paired filtration dialysis device is discharged, be connected with 4-dialysis solution circulation pipe again, 4-dialysis solution circulation pipe moves ahead and is connected with 6-dialysis solution pump line, driving through 7-dialysis liquid pump, attract dialysis solution to continue to proceed to 8-dialysis solution circulation input pipe, 1-dialysis solution circulation outlet tube and 8-dialysis solution circulation input pipe are all inserted in the 9-dialysis fluid container, the 10-dialysis fluid container is standby continued access dialysis solution, 9, the 10-dialysis fluid container, being placed on 11-electronics weight weighing apparatus surveys on the device pressure sensing applicator platform, below 11-electronics weight weighing apparatus survey device pressure sensing applicator platform is 12-pressure transducer and 13-electric transmission system, 13-electric transmission system electronics weight weighing apparatus survey that device 12-pressure transducer surveyed 9, the information bidirectional of 10-dialysis fluid container transfers to the 37-computer, accept and carry out the instruction of 37-computer, constitute the dialysis solution circulation of automatic hemodialysis filter, dialysis solution capacity and dialysate temperature monitoring system.
14-ductus arteriosus shown in Fig. 1, on the 14-ductus arteriosus, be combined with 15-transfusion short tube, 16-blood pump pipe is connected with 14 ductus arteriosuss, 16-blood pump pipe is housed in the 17-blood pump, 18-appends calparine pipe and is connected with the 14-ductus arteriosus, 19-heparin syringe appends calparine pipe with 18-and is connected, the other end of 14-ductus arteriosus and 5-dialyser, the dialysis-type dialysis filter, the arterial end of dialysis filter or filter or paired filtration dialysis device is connected, the 5-dialyser, the dialysis-type dialysis filter, the vein end of dialysis filter or filter or paired filtration dialysis device is connected with the 20-venous duct, coupled 21-bubble trap is arranged on the 20-venous duct, 22-exhaustor and 23-vein pressure pipe are arranged on the 21-bubble trap, 23-vein pressure pipe is connected with 24-venous pressure monitor and joint under application state, the automatic vascular clamp that 20-vein pressure pipe after the 21-bubble trap is walked around the 25-air monitor continues to move ahead, and has 26-blood sampling perforator to constitute the extracorporeal blood circulation system of automatic hemodialysis filter on the 20-venous duct.
5-paired filtration dialysis device among Fig. 2, what link to each other with the filtered solution tap of 5-paired filtration dialysis device is 27-filtered solution collecting pipe, 27-filtered solution collecting pipe is connected with 28-filtered solution collecting bag, what link to each other with 28-filtered solution collecting bag is 29-capacity monitor pick off hook, and 29-capacity monitor pick off hook combines with 30-capacity monitor pick off and constitutes the filtration fraction of paired filtration dialysis system; Be connected with 15-transfusion short tube on the 14-ductus arteriosus by 31-balance liquid bag and tube for transfusion, 31-balance liquid bag and tube for transfusion and 32-capacity monitor hook joins and 33-capacity monitor pick off constitutes the fluid infusion system and the filtered solution gathering system of paired filtration dialysis system together; 30-1 among Fig. 3 and 33-1 are 30 and the electric transmission system of 33-capacity monitoring sensor, link to each other with 37-1 computer cable line socket, constitute the paired filtration dialysis system jointly.
34-startup power supply shown in Fig. 3, combine with 37-computer cable line socket, 35-blood pump display screen, 36-gas monitor sonac links to each other with the automatic vascular clamp circuit of 21-bubble trap and 25-air monitor, the 37-computer, 38-dialysis liquid pump display screen, 39-elevator, the 40-reversible electric machine, combine with the 41-transmitting gear, affect at 42-under the affecting of chain, the sliding wheel that draws of 43-is moved up and down, under the affecting of offside 44-stainless steel wire rope, make to slide and draw wheel steadily to move up and down, 45-complete machine adnexa infusion support, 46-chassis, combine with 47-automatic control frame, 48-complete machine steering wheel has combined under the 47-automatic control frame.
49-dialysis solution among Fig. 4 warm external device (ED) of weighing apparatus of heating, the 50-dialysis solution circulation pipe among the 49-is placed in one, 51-heating member, 52-dialysis solution heat thermostat switch and display part.
Fig. 5, Fig. 1, shown in computer supervisory control system, extracorporeal blood circulation system is to be communicated with the energising of 17-blood pump by the 34-startup power supply, can show rotating speed, flow at 35-blood pump display screen after starting the 17-blood pump, and can adjust rotating speed and flow at 17-blood pump adjusting knob as required; 24-venous pressure monitor continuous monitoring venous pressure high and low, when venous pressure is too high or too low when meeting or exceeding threshold values, the 37-computer promptly instructs reports to the police immediately, instruct the stall of 17-blood pump simultaneously, after getting rid of the vein abnormal conditions, the 17-blood pump can recover to rotate, and proceeds treatment; When entering air, the 21-bubble trap reaches the critical horizontal plane, 36-gas monitor sonac is found out immediately, information is imported into the 37-computer, the stall of 37-computer immediate instruction 17-blood pump, instruct the automatic vascular clamp clamp of the 25-20-venous duct of 36-gas monitor simultaneously, prevent that gas from entering in patient's body, when getting rid of bubble from the 22-exhaustor, the 17-blood pump can recover to rotate, and proceeds treatment.
Fig. 5, Fig. 1, shown in computer supervisory control system, dialysis solution circulation, dialysate temperature, ultrafiltration and filtration fluid infusion system are after starting power initiation by 34-, be communicated with the energising of 7-dialysis liquid pump, promptly show rotating speed, flow after 7-dialysis liquid pump starts, and can adjust rotating speed and flow at the 7-1 adjusting knob of 7-dialysis liquid pump as required at 38-dialysis liquid pump display screen; On the screen of 37-computer, show simultaneously dialysate temperature ℃, if dialysate temperature is crossed low or too high, be below or above predetermined temperature value, the 37-computer is reported to the police immediately, 7-dialysis liquid pump can not start or stall, when dialysate temperature recovers normal, 7-dialysis liquid pump can start or recover to rotate, and proceeds to treat;
When 9, when the 10-dialysis fluid container is placed on the 11-weighing apparatus measuring device pressure sensing applicator platform, the 12-pressure transducer promptly imports information into the 37-computer, and the 37-computer i.e. measuring and calculating dialysis liquid measure and show with the milliliter digital display continuously; Treatment beginning 37-computer promptly writes down treatment time automatically, and with a minute expression, the dialysis solution total amount used in record simultaneously, ultrafiltration volume in the unit interval, and the ultrafiltration total amount, the filtration total amount is used the liquid total amount; Calculate continuously by the 37-computer and to judge that ultrafiltration volume, filtrable volume exceed standard? if ultrafiltration volume or filtrable volume surpass the milliliter number of desired indicator, promptly show the milliliter number of answering the fluid infusion total amount on the 37-computer screen, alarm needs the milliliter number of actual amount infused simultaneously.
Fig. 1, Fig. 2, Fig. 3, dialysis solution shown in Figure 5 another monitoring system that circulates is to be carried out under the monitoring of 37-computer by the 39-elevator, start power supply, the energising of 39-elevator, when completely the liquid bag hangs over high-order 32-capacity monitor pick off hook and hangs over empty liquid bag on the low level 29-capacity monitor pick off hook No. 1, the 37-computer is promptly measured the milliliter number of No. 1 fresh dialysis fluid automatically, dialysis solution is from No. 1 high position, flow into the 5-dialyser, flow out the 5-dialyser, flow into low level liquid bag No. 2, does the 37-computer judge that No. 1 liquid bag flows sky? if, the 39-elevator is rotated the 41-transmitting gear by the 40-reversible electric machine, drive 42-and affect chain, affect 43-1 and the sliding wheel that draws of 43-2-by the 42-chain again, the offside of chain is the 44-stainless steel wire rope, draw 43-1 and 43-2 from the negative, to stablize the sliding wheel that draws of 43-1 and 43-2 automatically along clockwise upset exchange 1, the position of No. 2 liquid bags (weight sensor 33 and 30), the number of times of record exchange simultaneously 1 time, show dialysate flow, fluid volume adds up, each ultrafiltration volume, the ultrafiltration total amount, filter total amount and should replenish liquid measure, if ultrafiltration volume is or/and filtrable volume surpasses predetermined target value, the 37-computer is reported to the police automatically and is shown that the milliliter number of answering the fluid infusion total amount is on screen, 31-balance liquid bag and tube for transfusion and the liquid that needs to replenish hang on the 32-capacity monitor pressure transducer hook, 15-transfusion short tube on tube for transfusion on the 31-balance liquid bag and the 14-ductus arteriosus is connected and carries out fluid infusion, the 37-computer is counted real amount infused, the real amount infused of continuous monitoring, is the 37-computer judged predetermined inferior the counting to not that exchange? if be less than, continue the upset exchange, if arrive, stop upset, notify from a phone call and change fresh dialysis solution, if have a power failure suddenly, the 37-computer is reported to the police automatically, notify from a phone call artificial exchange dialysis solution, if treatment time arrives, the order fulfillment treatment;
Fig. 1, Fig. 2, Fig. 3, Fig. 4, system monitoring shown in Figure 5 pass through to start power supply by the 37-computer, be communicated with 7-dialysis liquid pump, the 17-blood pump, with the 39-elevator, monitor three systems simultaneously, extracorporeal blood circulation system arrives the high and low of 37-computer monitoring venous pressure by ultrasonic monitor key monitoring 21-bubble trap by 24-venous pressure monitor and joint transmission information; The monitoring of dialysis solution blood circulation has two, and 1 is the blood circulation that is driven by 7-dialysis liquid pump, arrives the 37-computer by 12-pressure transducer transmission information, key monitoring dialysis solution total amount, dialysis fluid volume, ultrafiltration volume, filtrable volume needs amount infused and real amount infused; Another dialysis solution blood circulation is the dialysis solution blood circulation that is driven by the 39-elevator, key monitoring dialysis solution total amount, and the dialysis fluid volume, ultrafiltration volume, filtrable volume needs amount infused and real amount infused; By heat indirectly weighing apparatus temperature of the dialysis solution in the thermostat dialysis solution circulation pipe that 3-is heated, outside the dialysis solution circulation pipe in 3-heats thermostat, the 51-heating member is arranged and the WATER AS FLOW MEDIUM of heating, the dialysis solution circulation pipe is immersed in the WATER AS FLOW MEDIUM of the thermostat of heating, both can reach the purpose of the weighing apparatus temperature of heating, the cleaning that can keep the dialysis solution circulation pipe inner chamber in the WATER AS FLOW MEDIUM again, under the situation of not treating, with resistant to elevated temperatures 9, the 10-dialysis fluid container, regularly WATER AS FLOW MEDIUM is warmed to 98 ℃, can reach the purpose of sterilization, make the dialysis solution circulation pipe intracavity in the thermostat of heating keep aseptic environments; Under the situation of treatment, by the 37-computer, monitoring 51-heating member, when dialysate temperature was lower than threshold values, the 51-heating member heated automatically, and when dialysate temperature met or exceeded threshold values, the 51-heating member stopped heating, but keeps dialysate temperature in the scope of application.
Shown in Fig. 1-4 two cover dialysis solution liquid-supplying system is to be made of 7-dialysis liquid pump and 39-elevator, under the situation that electricity is arranged, both available 7-dialysis liquid pump liquid-supplying system, also available 39-elevator dialysis solution cyclic system liquid-supplying system, under situation about having a power failure, 29 and the 32-dialyzate bag hook of available 39-elevator carries out manual operations, continues to keep treatment.
Its feature of automatic hemodialysis filter shown in Figure 1 also is: the automatic control part (comprising: the 37-computer, the 17-blood pump, the 7-liquid pump of dialysing, the 24-venous pressure monitor, 36-gas monitor sonac, the 3-thermostat of heating), adopt the method manufacturing of split assembling to install with 47-automatic control frame and 39-elevator; The automatic control part can be separated independent use with the 39-elevator, also can fit together in indoor use.
Shown in Fig. 1-4 9, the 10-dialysis fluid container can be a macromolecular material, non-toxic polyvinyl chloride, polypropylene plastics, Merlon, polyester polyether sulfones etc. also can be stainless steel materials, 9, the capacity of 10-dialysis fluid container is one of 3500ml and 5500ml.The shape of dialysis fluid container can be long cube, also can be other shape.28-filtered solution collecting bag and 31-transfusion bag can be macromolecular materials, also can be vials, capacity 500ml, 1000ml, 1500ml, one of 2000ml.27-filtered solution collecting pipe and 31-liquid supplementation pipe can be macromolecular materials, comprising: plastics, medical grade silicon rubber or medical latex tube.
7-dialysis liquid pump shown in Fig. 1-4 can be roller (pearl) pump, also can be centrifugal pump, can also be gear pump or vane pump.The functional effect feature of pump is can keep dialysate flow at the 10-1000ml/ per minute.
6-1-carbamide biosensor shown in Figure 4 has urea concentration biological detection function, when filtered solution and/or ultrafiltrate during by 6-1-carbamide biosensor, 6-1-carbamide biosensor passes the urea concentration information of filtered solution and ultrafiltrate to the 37-computer, and the 37-computer can be shown in the urea concentration information analysis of filtered solution and ultrafiltrate on the screen.In the time need in therapeutic process, detecting the urea concentration of filtered solution and ultrafiltrate so that judge blood urea concentration indirectly, propose 9 or 10-dialysis fluid container or with clamp clamps 1-dialysis solution outlet tube 1-dialysis solution circulation pipe is temporary transient, at this moment promptly temporary no dialysis solution is by 5-dialysis-type dialysis filter, dialysis filter, the filterable form dialysis filter, dialyser, filter, filtered solution of being measured and/or the urea concentration in the ultrafiltrate, can judge the urea concentration in the blood indirectly, realize the automatic dynamic monitoring function of urea concentration biosensor, provide the dynamic experiment foundation for determining the further treatment time and the monitoring state of an illness.
The beneficial effect that the present invention is compared with prior art possessed mainly contains following aspect: (1) adapts to wide, because what this automatic hemodialysis filter adopted is technology with Chinese characteristics, independent design, domestic processing, though genus new high-tech product, but manufacturing cost is relatively low, so the present invention has the wide characteristics that adapt to.(2) though this product is the hemodialysis filtering therapy, exempted water treatment system, do not resembled the paired filtration dialysis machine of conventional hemo system and Bellc company manyly because of water consumption,, can satisfy the demand so prepare dialysis solution with aquae destillata.(3) this product does not rely on the water source, the situation of cutting off the water suddenly under, still can treat normally, this is all conventional hemo systems in present home and abroad and the not available function of paired filtration dialysis machine.(4) this product has two cover dialysis solution liquid-supplying systems, and automatic system and manual system even have a power failure suddenly, also can be finished the hemodialysis filtering therapy as usual in treatment.(5) this product adopts the method manufacturing of split assembling, can install and use indoor, and also separable automatic control part and elevator part are carried automatic control part main frame outward outside separately and examined rescue.(6) design of dialysis solution liquid-supplying system is ingenious, and medical personnel can keep in repair when being out of order voluntarily.(7) this product is not high to environmental requirement, is adapted at treating in the multiple environment.(8) price is cheaper, respond well than the paired filtration dialysis machine of conventional import hemo system and Bellc company, and domestic medical institutions and patient can both be accepted.(9) machine volume is little, uses floor space little, the treatment place of arranging complete machine easily.(10) structure is simple and direct, easily learning and mastering.(11) the used consumable goods of this product can be the dialyser of present prior art, filter, paired filtration dialysis device; Also can be the dialysis-type dialysis filter, dialysis filter and filterable form dialysis filter; Can also be blood perfusion device, plasma separator except that carrying out hemofiltration dialysis and the saturating ultrafiltration of blood, also can carry out hemoperfusion and replacement therapy of blood plasma.The used manufactured materials of this product source light is extensively anti-general, and low price is made easily.
Realize that the good mode of amount of the present invention is: according to shown in Figure 1, the main accessory that needs to prepare has: 1, roller pump is two, does blood pump (17) for one, and another makees dialysis liquid pump (7), makees the motor of dialysis liquid pump (7) and wants suitable heavy-duty motor; 2, computer (37) is the single-chip microcomputer by the design of this product computer programme flow diagram; 3, the dialysis solution thermostat (3) of heating is processed according to shown in Figure 4; 4, dialysis fluid container (9,10) is by processing among Fig. 1-4; 5, elevator (39) external device (ED), reversible electric machine (40), transmitting gear (41) affects chain (42), sliding wheel (43-1 and 43-2), stainless steel wire rope (44), the infusion support (45) of drawing, chassis (46), automatic control frame (47), steering wheel (48) is purchased respectively and is carried out machined; 6, dialyser, filter, paired filtration dialysis device, the dialysis-type dialysis filter, filter, the filterable form dialysis filter, arterio-venous catheter can be purchased.The accessory by specification is prepared shown in other figure.The accessory equipment of being prepared is assembled shown in Fig. 1-4, can manufacture automatic hemodialysis filter.

Claims (7)

1, a kind of automatic hemodialysis filter and working procedure thereof, the present invention is by extracorporeal blood circulation system; Dialysis solution circulation, dialysis solution capacity, dialysate temperature monitoring system; Saturating folding filtration system and computer automatic monitored control system constitute.The invention is characterized in:
A. dialysis solution circulation, the dialysis solution capacity, filter, the ultrafiltrate urea concentration, the temperature detection monitoring system is to be connected and to be imported dialysis solution by dialysis solution circulation outlet tube (1) and the dialysis solution thermostat junction block (2-1) of heating, dialysis solution is warm through the weighing apparatus of heating in dialysis solution is heated thermostat (3), export dialysis solution circulation pipe (4) to from dialysis solution another junction block of thermostat (2-2) of heating, and and dialyser, the dialysis-type dialysis filter, the dialysate hole of dialysis filter or filter or paired filtration dialysis device (5) one ends is connected, dialysis solution is from dialyser, the dialysis-type dialysis filter, after the dialysate hole of dialysis filter or filter or paired filtration dialysis device (5) other end is discharged, be connected with dialysis solution circulation pipe (4), dialysis solution circulation pipe (4) moves ahead and is connected with dialysis solution pump line (6), carbamide biosensor (6-1) is arranged on dialysis solution pump line (6), driving through dialysis liquid pump (7), attract dialysis solution to continue to proceed to dialysis solution circulation input pipe (8), dialysis solution circulation outlet tube (1) and dialysis solution circulation input pipe (8) are all inserted in the dialysis fluid container (9), dialysis fluid container (10) is standby continued access dialysis solution, dialysis fluid container (9,10) being placed on electronics weight weighing apparatus surveys on the device pressure sensing applicator platform (11), the below of surveying device pressure sensing applicator platform (11) at electronics weight weighing apparatus is pressure transducer (12) and electric transmission system (13), electric transmission system (13) surveys the dialysis fluid container (9 that device pressure transducer (12) is surveyed to electronics weight weighing apparatus, 10) information bidirectional transfers to computer (37), accept the instruction of object computer, constitute the dialysis solution circulation, the dialysis solution capacity, filter and/or the ultrafiltrate urea concentration dialysate temperature monitoring system.
B. extracorporeal blood circulation system is by ductus arteriosus (14), transfusion short tube (15) is connected with ductus arteriosus (14), blood pump pipe (16) is connected with ductus arteriosus (14), blood pump pipe (16) is housed in blood pump (17), appending calparine pipe (18) is connected with ductus arteriosus (14), heparin syringe (19) with append calparine pipe (18) and be connected, the other end and the dialyser of ductus arteriosus (14), the dialysis-type dialysis filter, the arterial end of dialysis filter or filter or pairing dialysis filter (5) is connected, dialyser, the dialysis-type dialysis filter, the vein end of filter or dialysis filter or pairing dialysis filter (5) is connected with venous duct (20), coupled bubble trap (21) is arranged on venous duct, exhaustor (22) and vein pressure pipe (23) are arranged on bubble trap (21), vein pressure pipe (23) is connected with venous pressure monitor and joint (24) under application state, the automatic vascular clamp (25) of venous duct (20) through walking around air monitor after the bubble trap continues to move ahead, and has blood sampling perforator (26) to constitute extracorporeal blood circulation system jointly on venous duct (20).
C. the paired filtration dialysis system is by paired filtration dialysis device (5), what link to each other with the filtered solution tap of paired filtration dialysis device (5) is filtered solution collecting pipe (27), filtered solution collecting pipe (27) is connected with filtered solution collecting bag (28), and capacity monitor pick off hook (29) that links to each other with filtered solution collecting bag (28) and capacity monitor pick off (30) constitute the filtration fraction of paired filtration dialysis system; By balance liquid dress and tube for transfusion (31), tube for transfusion is connected with transfusion short tube (15) on the ductus arteriosus, the balance liquid bag links to each other with capacity monitor pick off hook (32) with tube for transfusion (31), fluid infusion part with capacity monitor pick off (33) formation paired filtration dialysis system, the electric transmission system (30-1 and 33-1) of capacity monitor pick off (30) and capacity monitor pick off (33) links to each other with computer cable line socket (37-1), constitutes the paired filtration dialysis system jointly.
D. computer supervisory control system is by (1) extracorporeal circulation of blood monitoring system; (2) dialysis solution circularly monitoring system; (3) dialysate temperature monitoring system; (4) filtration, ultrafiltration, amount infused monitoring system; (5) filtration, ultrafiltrate urea concentration monitoring system; (6) system monitoring six parts constitute.
The extracorporeal blood circulation system monitoring is by starting power supply (34), be communicated with blood pump (17) energising, after starting, blood pump (17) can show rotating speed at blood pump display screen (35), flow, and can adjust rotating speed and flow at the adjusting knob (17-1) of blood pump (17) as required, the height of venous pressure monitor (24) continuous monitoring venous pressure, low, when venous pressure is too high or too low when meeting or exceeding threshold values, computer (37) instruction is reported to the police immediately, instruct blood pump (17) stall simultaneously, after getting rid of the venous pressure abnormal conditions, blood pump (17) can recover to rotate, proceed treatment, when entering air, bubble trap (21) reaches the critical level face, after gas monitor sonac (36) is found out immediately, information is imported into computer (37), computer (37) immediate instruction blood pump (17) stall, instruct automatic vascular clamp (25) the clamp venous duct (20) of air monitor simultaneously, prevent that gas from entering in patient's body, when getting rid of bubble from exhaustor (22), blood pump (17) can recover to rotate, and proceeds treatment;
Dialysis solution circulation, dialysate temperature, ultrafiltration and filtration fluid infusion monitoring system are by after starting power supply (34) startup, be communicated with dialysis liquid pump (7) energising, can show rotating speed, flow at dialysis liquid pump display screen (38) after dialysis liquid pump (7) starts, and can adjust rotating speed and flow at the adjusting knob (7-1) of dialysis liquid pump (7) as required; In the time of on dialysis fluid container (9,10) being placed on weighing apparatus measuring device pressure sensing applicator platform (11), pressure transducer (12) promptly imports information into computer (37), and computer (37) is promptly continuously calculated the dialysis liquid measure and shown with the milliliter digital display; Treatment beginning computer (37) promptly writes down treatment time automatically, and with minute calculating, the dialysis solution total amount used in record simultaneously, ultrafiltration volume in the unit interval, ultrafiltration total amount, filtration total amount; Do you judge that by continuous calculating of computer (37) ultrafiltration volume, filtrable volume exceed standard? if ultrafiltration volume meets or exceeds desired indicator, promptly show the milliliter number of answering the fluid infusion total amount on computer (37) screen automatically, and alarm needs the milliliter number of actual amount infused; On the screen of computer (37), show simultaneously dialysate temperature ℃, if dialysate temperature is crossed low or too high, be below or above predetermined temperature, computer (37) is reported to the police immediately, dialysis liquid pump (7) can not start or stall, when dialysate temperature recovers normal, dialysis liquid pump (7) can start or recover to rotate, and proceeds to treat;
Circulate another monitoring system and fluid infusion system of dialysis solution is to be carried out under the monitoring of computer (37) by elevator (39), start power supply, elevator (39) energising, when No. 1 full liquid bag being hung over high bit capacity monitor pick off hook (32) and No. 2 empty liquid bags is hung over low bit capacity monitor pick off hook (29) and go up, computer (37) is promptly measured the milliliter number of No. 1 fresh dialysis fluid amount automatically, dialysis solution is from No. 1 high-order liquid bag, flow into dialyser (5), flow out dialyser (5), flow into low level liquid bag No. 2, does computer (37) judge that No. 1 liquid bag flows sky? if, elevator (39) affects chain (42) by reversible electric machine (40) transmitting gear (41), affects the sliding wheel (43-1) that draws by chain (42) again, (43-2), the offside of chain is that stainless steel wire rope (44) draws the sliding wheel (43-1 that draws from the negative; 43-2), with the stable sliding wheel (43-1 that draws; 43-2), automatically along clockwise upset exchange 1, the position of No. 2 liquid bags (weight sensor 33 and 30), the number of times of record exchange simultaneously 1 time, show dialysate flow, this moment, No. 2 liquid bags were in a high position, No. 1 liquid bag is at low level, dialysis solution flows into dialyser (5) from No. 2 liquid bags, flow out dialyser (5), flow into No. 1 the liquid bag, does computer (37) judge that No. 2 liquid bags flow sky? if, elevator (39) is contra solem upset exchange 2 automatically, the position of No. 1 liquid bag (weight sensor 30 and 33), the number of times of record exchange simultaneously 1 time, show dialysate flow, fluid volume adds up, each ultrafiltration volume, the ultrafiltration total amount, filter total amount and answer amount infused, if ultrafiltration volume is or/and filtrable volume surpasses predetermined target value, computer (37) is reported to the police automatically and is shown that the milliliter number of answering the fluid infusion total amount is on screen, the liquid that will replenish (31) is hung on the capacity monitor pressure transducer hook (32), tube for transfusion is connected with transfusion short tube (15) on the ductus arteriosus (14) and carries out fluid infusion, computer (37) is counted real amount infused, are the real amount infused of continuous monitoring, computer (37) judged predetermined inferior the counting to not that exchange? if be less than, continue the upset exchange, if arrive, stop upset, notify from a phone call and change fresh dialysis fluid, if having a power failure suddenly, computer (37) is the newspaper pipe automatically, notify from a phone call artificial exchange dialysis solution, treatment time arrives, the order fulfillment treatment.
Filtered solution, ultrafiltrate urea concentration monitoring system is to be finished by carbamide biosensor (6-1) and computer (37), when temporarily dialysis solution circulation pipe (1) being proposed outside the dialysis fluid container (9 or 10) or with clamp clamps dialysis solution circulation outlet tube (1), this moment the dialysis solution flow stoppage, have only filtered solution and/or ultrafiltrate by the dialysis solution circulation pipe carbamide biosensor (6-1) of flowing through, carbamide biosensor (6-1) is passed to computer (37) to the information of being monitored, the concentration of carbamide in filtered solution and/or the ultrafiltrate is analyzed and demonstrated to computer (37) as calculated, as the foundation of determining further treatment time and the dynamic change of the monitoring state of an illness.
The system monitoring system is by starting power supply by computer (37), be communicated with dialysis liquid pump (7), blood pump (17), elevator (39), Jian Kong three systems simultaneously, extracorporeal blood circulation system is monitored venous pressure high and low by venous pressure monitor and joint (24) transmission information to computer (37) by ultrasonic detector key monitoring bubble trap (21); The monitoring of dialysis solution blood circulation has two, one is the blood circulation that dialysis liquid pump (7) drives, and arrives computer, key monitoring dialysate temperature by pressure transducer (12) and the thermostat of heating (3) transmission information, ultrafiltration volume, filtrable volume need amount infused and real amount infused; Another system is the dialysis solution blood circulation that is driven by elevator, key monitoring ultrafiltration volume, filtrable volume, need amount infused and real amount infused.
The complete machine of automatic hemodialysis filter is characterised in that: complete machine has adnexa infusion support (45), and chassis (46), chassis (46) are connected mutually with automatic control frame (47), and automatic control frame (47) is connected mutually with complete machine steering wheel (48).
2, the described automatic hemodialysis filter of root a tree name claim 1, it is characterized in that: the dialysis solution liquid-supplying system is to be made of dialysis liquid pump (7) and elevator (39) two cover liquid-supplying systems, under the situation that electricity is arranged, the also available elevator of both available dialysis liquid pump (7) liquid-supplying system (39) dialysis solution blood circulation, under situation about having a power failure, can utilize the liquid bag hook (29,32) of elevator (39) to carry out manual operations, continue to keep treatment.
3, automatic hemodialysis filter according to claim 1, its feature also is: the automatic control part (comprising: computer (37), blood pump (17), dialysis liquid pump (7), venous pressure monitor (24), gas monitor sonac (36), the thermostat of heating (3)) install with the method manufacturing of split assembling with automatic control frame (47) and elevator (39); The automatic control part can be separated use separately with elevator (39), also can fit together in indoor use.
4, the described automatic hemodialysis filter of root a tree name claim 1, its feature also is: dialysis fluid container (9,10) can be macromolecular material such as vinyon, non-toxic polyvinyl chloride, polypropylene plastics, Merlon etc., also can be stainless steel material, the capacity of dialysis fluid container (9,10) be one of one of 3500ml and 5500ml.The shape of dialysis fluid container can be long cube, also can be other shape.Filtered solution collecting bag (28) and transfusion bag (31) can be macromolecular materials, also can be vials, and capacity is 500ml, 1000ml, 1500ml, one of 2000ml.Filtered solution collecting pipe (27) and liquid supplementation pipe (31) can be macromolecular materials, comprising: plastics, medical grade silicon rubber or medical latex.
5, its feature of automatic hemodialysis filter according to claim 1 also is: dialysis liquid pump (7) can be roller (pearl) pump, also can be centrifugal pump, can also be negative-pressure vacuum pump, gear pump or vane pump.
6, its feature of automatic hemodialysis filter according to claim 1 also is: the dialysis solution thermostat (3) of heating is by external device (ED) (49), and dialysis solution circulation pipe (50), heating member (51) and switch are regulated heating-up temperature display part (52) and constituted; Employing is to the method for the weighing apparatus temperature of heating indirectly by the dialysis solution in the dialysis solution circulation pipe in the thermostat of heating (3) the weighing apparatus temperature of heating, outside the dialysis solution circulation pipe in the thermostat of heating (3), the having heaters and the warm WATER AS FLOW MEDIUM of weighing apparatus of heating, the dialysis solution circulation pipe is immersed in the WATER AS FLOW MEDIUM of the thermostat of heating, both can reach the weighing apparatus temperature of heating, can keep clean again, under the situation of not treating, regularly WATER AS FLOW MEDIUM is warmed to 98 ℃, can reach the purpose of sterilization, make the dialysis solution circulation pipe intracavity in the thermostat of heating keep aseptic environments.
7, its feature of automatic hemodialysis filter according to claim 1 also is: dialysis solution circulation pipe (6) is provided with urea concentration biosensor (6-1), when in therapeutic process, carrying out the urea concentration monitoring, dialysis solution circulation pipe (1) temporarily proposed outside the dialysis fluid container (9 or 10) or with the outlet tube (1) of clamp clamps dialysis solution circulation pipe, at this moment have only filtered solution and/or ultrafiltrate from 5-dialysis-type dialysis filter, dialysis filter, the filterable form dialysis filter, the dialysate hole of dialyser and filter flows out, when flowing to urea concentration biosensor (6-1), urea concentration biosensor (6-1) can pass to computer (37) to the carbamide concentration information, computer (37) is presented at the concentration of carbamide in filtered solution of measuring and/or the ultrafiltrate on the screen, urea concentration in the circulation of indirect detection patient's body inner blood, realize the automatic measuring ability of urea concentration biosensor, provide the dynamic experiment foundation for further determining treatment time and monitoring change of illness state.
CN 98112254 1998-09-17 1998-09-17 Automatic hemodialysis filter Pending CN1235849A (en)

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