CN1200743C - 带有多腔连接器的伤口抽吸装置 - Google Patents

带有多腔连接器的伤口抽吸装置 Download PDF

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CN1200743C
CN1200743C CNB008182388A CN00818238A CN1200743C CN 1200743 C CN1200743 C CN 1200743C CN B008182388 A CNB008182388 A CN B008182388A CN 00818238 A CN00818238 A CN 00818238A CN 1200743 C CN1200743 C CN 1200743C
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connector part
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suction tube
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K·P·赫顿
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KCI Licensing Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/71Suction drainage systems
    • A61M1/73Suction drainage systems comprising sensors or indicators for physical values
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61F13/05
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/84Drainage tubes; Aspiration tips
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/90Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
    • A61M1/91Suction aspects of the dressing
    • A61M1/912Connectors between dressing and drainage tube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/90Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
    • A61M1/91Suction aspects of the dressing
    • A61M1/915Constructional details of the pressure distribution manifold
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/90Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
    • A61M1/96Suction control thereof
    • A61M1/966Suction control thereof having a pressure sensor on or near the dressing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M27/00Drainage appliance for wounds or the like, i.e. wound drains, implanted drains
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/71Suction drainage systems
    • A61M1/74Suction control
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/71Suction drainage systems
    • A61M1/74Suction control
    • A61M1/75Intermittent or pulsating suction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3331Pressure; Flow
    • A61M2205/3344Measuring or controlling pressure at the body treatment site
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10Tube connectors; Tube couplings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10Tube connectors; Tube couplings
    • A61M39/105Multi-channel connectors or couplings, e.g. for connecting multi-lumen tubes

Abstract

公开了一种用于对伤口部位施加负压以促进伤口愈合设备。该设备包括:一用来作用于伤口的多孔垫;一连接多孔垫与负压源的吸入管;一用于收集伤口渗出液的容器,其设在多孔垫与负压源之间;以及一可快速断开的连接器,其将通向多孔垫的吸入管的第一部段与通向该容器的第二部段连接起来,该连接器包括不可互换的两个可分离的部分,吸入管的该第一部段包括一多腔管,其中一个腔设置用来对多孔垫进行抽吸,而另一个腔设置用来监测压力,该多腔管在一端处固定地连接到容器上,而在另一端处固定地连接到该可分离的部分的其中一个上,该可分离部分包括密封装置,由此各个腔以气密的方式连接到吸入管的该第二部段上。

Description

带有多腔连接器的伤口抽吸装置
技术领域
本发明涉及一种设备,该设备用于对伤口进行负压治疗。负压治疗的原理是基于这样一个事实,即对一个敞开的伤口连续地或间歇地进行抽吸,便可能由于刺激了伤口停滞区域的血液流动而促使伤口较快愈合。这种治疗方法现在已经被大家接受作为一种高效的途径来对褥疮、溃疡、局部深度烧伤及手术后伤口不能快速愈合的病人进行治疗以改善其伤口的愈合。
背景技术
PCT专利申请WO 96/05873描述了一种对伤口进行负压治疗的设备,该设备包括一个与吸入管相连的多孔垫以及设在抽吸装置和多孔垫之间的容器,该容器是用来收集伤口渗出物的。英国专利申请9623743.3(公布号No.2307180)又公开了上述PCT申请所述设备的一改进,该设备感受作用到伤口部位上的实际压力。尽管上述申请中的设备能有效地工作,但当需要将从病人上断开和再连接吸入管时存在一些实际应用中缺点。
发明内容
本发明提供一种经过改进的设备,其包括一简便的系统以用于吸入管线与伤口部位连接和断开。
根据本发明的一个方面,提供了一种用于对伤口进行负压治疗的设备,其包括:应用到伤口上的多孔垫;连接多孔垫与负压源的多腔吸入管,该多腔吸入管包括设置成用来对多孔垫进行抽吸的第一腔和设置成用来监控压力的第二腔;用于收集伤口渗出液的容器,其设在该多孔垫与该负压源之间;以及可快速断开的连接器,其将通向该多孔垫的该吸入管的第一部段与通向所述容器的第二部段连接起来,所述可快速断开的连接器包括:第一连接器部分,其可与第二连接器部分互锁和与该第二连接器部分分离,该第一连接器部分具有主开口,该主开口提供通向该第一腔内部的进入口,该第二连接器部分具有管状突出部,该管状突出部适于穿过第一连接器部分的该主开口,由此使得该吸入管的第一部段和第二部段的第一腔连接起来,该第一连接器部分还具有一肩部,其用于与该第二连接器部分的凹口接合,其中该肩部提供用于该第二腔的通道,并且该第一和该第二连接器部分的接合形成横跨该吸入管的该第一和该第二部段之间的该第二腔的气密密封。
优选的是,连通到多孔垫上的管部段也是多腔管,并且该多腔管也固定地连接到可分离的连接器部分和适配器上,该适配器与多孔垫密封连接。
这里的术语“固定地连接”的意味着,所述部件彼此连接成,如果不将连接部件中的一个或两个都破坏则不能将其拆开。连接器的各个部分以及吸入管通常由塑料材料制成,并且各部件可以用焊接或粘结剂来进行固定地连接。一个简便的固定连接方法是使用部件的互溶剂。
本发明的一优点是:容器组件和固定地连接的吸入管仅与正确且配套的吸入管段和相关的多孔垫结合使用。因此,用来进行抽吸的腔道的两部段之间形成有适合且有效的密封,并且在一个管段中的“传感”腔与另一个管段中的对应“传感”腔或与该管段中的“抽吸”腔将密封地连接起来。结果,可以对伤口部位及附近区域的压力进行可靠的监测。
附图说明
通过下面的描述及附图,本发明的其它方面的内容、特征及优点将十分明显,其中:
图1所示为本发明设备的局部示意图;
图2所示为连接器的两个可分离部分以及装接在其上的多腔管的一部分;
图3所示为连接器的两个部分装配在一起时的情况;
图3a所示为图3中所标注部位的放大图;
图4及5所示为连接器的两个部分的不同方向的视图;
图6所示为一种改型的连接器;
图7、7a及7b所示为一个三通连接器的透视图;以及
图8a、8b、及8c所示为适配器的几种改型以及将适配器与伤口部位密封相连的系统。
具体实施方式
参见附图,特别是从图1中可见本发明的设备包括一个多孔垫1(例如敞开孔聚合泡沫,诸如具有互连孔的聚氨酯或聚乙烯醇泡沫),该垫1打算放到待治疗伤口之中或之上。该多孔垫通过适配器3及吸入管2与一个诸如泵或真空罐的负压源103相连,连接方式如前面提到的英国专利申请No.2307180和我们的正在审理中的英国专利申请No.9819678.5(公布号No.2329127)所述。适配器3优选为具有如英国专利申请No.9819678.5(公布号No.2329127)所述的构造。多孔垫及适配器3使用如英国专利申请No.2307130或No.2329127所述的手术单(surgical drape)以气密的方式与伤口部位密封。吸入管2在一端4处与适配器3的管口部5固定连接。可以使用诸如焊接或粘结剂粘接等任何适用手段来实现端部4和管口部5之间的固定连接及密封。合适的做法是将一种用于适配器和吸入管材料的溶剂涂覆在吸入管的外表面上,并将该管子插入适配器以形成粘结剂的粘接。吸入管2的另一端和伤口渗出物容器6的进口端7以适用的方式气密地固定密封。吸入管2由两个部分组成,这两部分之间以连接器8来连通。连接器8包括两个可分离的部分9及10,这使得病人可以容易地并快速地和设备的主体部分脱离开,例如为了接受其它治疗。将适配器3连接到连接器半部9的吸入管1的部段11完全地延伸进入连接器半部9之内,并以例如粘结剂粘接或焊接的方法将该部段密封于其中。因此,该管部段11在其两端处都是密封的。
与此相似,吸入管2的第二部段12将连接器的半部分10和渗出物收集容器6相连,该第二部段12也密封在其相应的连接器半部分10之内。因此,适配器3和连接器8之间以及连接器8和容器6之间都不可能存在空气泄漏。连接器8设计成当其两半部分组装在一起时便能锁定在密封状态。连接器的构造将在下面作更详细的描述。
吸入管2的部段12是一多腔管,该多腔管具有一个用来对伤口部位进行抽吸的中心腔道以及一个或多个用来感受伤口部位压力的周边腔道。共同未决的英国专利申请No.9819678.5(公布号No.2329127)中描述了一些多腔管的实例。
部段11最好也是一多腔管。但也不是必须如此,特别是当位于连接器半部分9和病人之间的部段11的长度相对较短时。在这种情况下,从连接器8处感受到的压力和从伤口部位感受到的压力基本上相等。
在容器6处,中心腔道与管子20相连,该管子20经由通道21连通到容器6的内部。可以通过例如管子22对容器6进行抽吸,以将抽吸作用施加到伤口部位上。一个或多个周边腔道与周边通道23连通,该周边通道与腔室24相连。腔室24通过通道25连到传感器10上,用于对连接器8处或伤口部位的压力进行测量。通道25还可连接一与大气连通的阀门102,以释放或减小伤口部位的负压。通过打开或不时地关闭阀门102,便可中断或改变作用在伤口上的负压。
管子22连接到负压源,例如泵103。管子22上还连接有压力传感器104来检测吸入管路中的压力。
图2到图5更详细地示出了连接器。
如图2所示,连接器半部分9具有一肩部30,此肩部30进入到连接器半部分10中的一个凹口内,并紧靠O型圈31密封。连接器半部分10具有一管形的突出部32,该突出部32的尺寸设计成:该突出部32能够进入多腔管11的中心腔道33,并且当连接器8处于完全装配状态时一增大部分35在中心腔道33内形成密封。连接器半部分10具有一些通道36,这些通道36的一端与多腔管的一个或多个周边腔道37相连通,而另一端和中心突出部32外侧空间38相通。
两个半部分9及10在其封闭状态中通过一卡口装配件保持在一起,该卡口装配件包括凸起部39及与之接合的槽口40。形成凸起部39和槽口40的相互接合表面确定成:使两个半部分9及10紧固在一起,以压缩O型圈,并迫使增大部分35稳固地进入内腔道33。图3清楚地示出了装配完成的状态。由图可见,当装配完成时,中心腔道33通过多腔管的二部分之间的中空突出部32得到连通,并且此腔道和与吸入管各部段中的周边腔道37相连通的传感器部分是完全隔开的。
适于制作管子的材料包括聚氯乙烯,适于制作连接器的材料包括聚氯乙烯、聚丙烯和ABS。可以借助于诸如环己醇胶的溶剂胶或通过可紫外线固化的粘结剂组合物来将管子密封在连接器半部分内。为了防止多腔管的部段11、12在拆卸时发生泄漏,连接器的两个半部分在分离之前可在管子上夹上夹子50。
图6所示为一个连接器的变型,该连接器在其两个半部分分离时会自动保持密封效果。该连接器和图2及3所示的连接器基本相同,其不同点在于具有一横截于多腔管的中心部分33或吸入管部11的整个开口端部的橡胶膜16。连接器半部分10的突出部分32的形状是具有一个能够刺破橡胶膜60的尖端部61。该突出部分32具有一与其内部连通的侧向孔62。这样,当连接器的两个部分9、10连接为一体时,该尖端部61便穿透橡胶膜60,并将吸入管11、12的两个中心腔道连通。膜60设计成当突出部分32抽出时可自动密封的柔软材料。于是,当吸入管11从连接器半部分10上脱离开时伤口渗出物就不会从管端泄漏出。
在一些情况中,例如对很大的伤口进行治疗或是需要对肢体的两侧同时进行治疗时,就适于使用分开的多孔垫或是必须使用很大的多孔垫。在这种情况下,合适的是设置两个适配器5,这两个适配器5都通过吸入管11连接到抽吸装置及渗出物容器6上。在这些情况下,不必分别地将管子连接到容器上,而可以设置一个Y形或T形的连接件,其中两个管臂连接分开的管子11以通向分开的适配器,第三管臂则连接收集容器。图7中示出了两个Y形连接件。Y形连接件本体的三个管臂上各设置有一个可分离部件80或81,每个可分离部件都分别与一对应部件相连接,该对应部件与相应管部段固定地连接。
连接器部件80和一多腔管部段相连,该多腔管部段的另一端和容器6密封地相连。连接器的其它部件可以和吸入管的其它管段固定连接,这些管段中的每一个连通到一适配器3上。对于一个大的伤口,可以设置两个适配器来对同一个伤口进行抽吸。尽管从Y形连接件连接到适配器的吸入管段可以是多腔管,但也不一定必须是多腔管,如果吸入管段是多腔管,这将使Y形连接件的构造非常复杂。假使是这样的话,虽然在伤口部位处感受的压力是两个适配器处压力的平均值,但是它们通常充分地靠近以至于压力差非常小。图7a及7b十分清楚地示出了卡口装配件的情况。
图8a、8b及8c示出了将适配器组件密封到伤口上的布置方式。图8a为适配器组件贴附到伤口200上的截面图。一个例如聚氨脂泡沫材料的多孔包敷件1包扎在创腔内,适配器3压靠在包敷件1的表面上。由图8a至8c可见,适配器凸缘301的下侧面被突起部302覆盖,这些突起部交叉地排列布置以便有助于流体能从大范围的泡沫垫1上流入适配器的管口部5。适配器3及包敷件通过一层弹性体材料薄板303密封在创腔内,这层弹性体材料薄板通过粘性的压敏粘结剂贴在伤口200周围的皮肤304上。弹性体材料薄板303通常是聚氨酯薄膜,该薄板的一端面上整个地涂覆了粘结剂,从而使该薄板如粘接在病人皮肤上同样地粘接在凸缘301的上表面上。
图8b是从适配器上方观察的平面图,其示出了围绕适配器的手术单(surgical drape)组件305。手术单组件和适配器的凸缘是透明的,因此可以看到突起部302。由图8c可以清楚地看到手术单组件包括三层薄板材料。手术单组件的最下层306是一层涂有脱离剂的较硬的材料薄板,这层材料薄板轻度地粘贴在手术单307本身的涂有粘结剂的下端面上。后者材料是一种很薄而柔软的弹性体材料。一层较厚的加强层308覆盖在手术单层307上。层307和层308具有供适配器管口部5通过的孔。使用时,先将泡沫垫1放入伤口,再揭去脱离层306并将手术单的粘接剂面粘贴到垫1周围的皮肤上,以形成气密密封。加强层308可在手术单粘贴到皮肤上之前、同时、或之后揭去。较厚材料的操作条310装接在手术单层的端部和加强层的端部,以助于将手术单粘贴到皮肤上以及便于将加强层从手术单上揭下。在达到密封效果以后,便可从手术单层上除去操作条310,穿孔311便是为此而设置的。

Claims (9)

1.一种用于对伤口进行负压治疗的设备,其包括:
应用到伤口上的多孔垫;
连接多孔垫与负压源的多腔吸入管,该多腔吸入管包括设置成用来对多孔垫进行抽吸的第一腔和设置成用来监控压力的第二腔;
用于收集伤口渗出液的容器,其设在该多孔垫与该负压源之间;以及
可快速断开的连接器,其将通向该多孔垫的该吸入管的第一部段与通向所述容器的第二部段连接起来,所述可快速断开的连接器包括:
第一连接器部分,其可与第二连接器部分互锁和与该第二连接器部分分离,
该第一连接器部分具有主开口,该主开口提供通向该第一腔内部的进入口,
该第二连接器部分具有管状突出部,该管状突出部适于穿过第一连接器部分的该主开口,由此使得该吸入管的第一部段和第二部段的第一腔连接起来,
该第一连接器部分还具有一肩部,其用于与该第二连接器部分的凹口接合,其中该肩部提供用于该第二腔的通道,并且该第一和该第二连接器部分的接合形成横跨该吸入管的该第一和该第二部段之间的该第二腔的气密密封。
2.如权利要求1所述的设备,其特征在于,其还包括位于第二连接器部分的凹口中的O型圈,该O型圈提供横跨该吸入管的该第一和该第二部段之间的气密密封。
3.如权利要求2所述的设备,其特征在于,其还包括在第一连接器部分中的突出部,该突出部用于与在第二连接器部分中的槽口接合,第一连接器的突出部接合在第二连接器的槽口中,由此压缩该O型圈。
4.如上述权利要求1所述的设备,其特征在于,该管状突出部具有增大部分,其适于密封该第一腔的内部。
5.如上述权利要求4所述的设备,其特征在于,其还包括在第一连接器部分中的突出部,该突出部用于与在第二连接器部分中的槽口接合,第一连接器的突出部接合在第二连接器的槽口中,由此迫使该管状突出部的该增大部分稳固地进入该第一腔的内部。
6.如上述权利要求5所述的设备,其特征在于,其还包括定位在该第二连接器部分的凹口内的O型圈,第一连接器的突出部接合在第二连接器的槽口中,由此压缩该O型圈并提供横跨该吸入管的该第一和该第二部段之间的气密密封。
7.如上述权利要求1-6中任一项所述的设备,其特征在于,该第二连接器部分的凹口设置在该第二连接器部分的管状突出部的外周附近。
8.如上述权利要求1-6中任一项所述的设备,其特征在于,其还包括设置成横跨第一连接器部分的主开口的自密封的薄膜。
9.如上述权利要求8所述的设备,其特征在于,其还包括在第二连接器部分的管状突出部上的尖端,所述尖端在操作上可刺穿该自密封的薄膜。
CNB008182388A 1999-11-09 2000-11-08 带有多腔连接器的伤口抽吸装置 Expired - Lifetime CN1200743C (zh)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101257877B (zh) * 2005-06-29 2013-07-17 应用纸巾技术有限公司 伤口敷裹

Families Citing this family (188)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458109B1 (en) 1998-08-07 2002-10-01 Hill-Rom Services, Inc. Wound treatment apparatus
GB9926538D0 (en) 1999-11-09 2000-01-12 Kci Medical Ltd Multi-lumen connector
US6764462B2 (en) 2000-11-29 2004-07-20 Hill-Rom Services Inc. Wound treatment apparatus
US6824533B2 (en) 2000-11-29 2004-11-30 Hill-Rom Services, Inc. Wound treatment apparatus
US20010041869A1 (en) * 2000-03-23 2001-11-15 Causey James D. Control tabs for infusion devices and methods of using the same
GB0011202D0 (en) 2000-05-09 2000-06-28 Kci Licensing Inc Abdominal wound dressing
AU2001261595A1 (en) 2000-05-22 2001-12-03 Arthur C. Coffey Combination sis and vacuum bandage and method
US6855135B2 (en) 2000-11-29 2005-02-15 Hill-Rom Services, Inc. Vacuum therapy and cleansing dressing for wounds
US6685681B2 (en) 2000-11-29 2004-02-03 Hill-Rom Services, Inc. Vacuum therapy and cleansing dressing for wounds
US7004915B2 (en) * 2001-08-24 2006-02-28 Kci Licensing, Inc. Negative pressure assisted tissue treatment system
WO2003030966A1 (en) * 2001-10-11 2003-04-17 Hill-Rom Services, Inc. Waste container for negative pressure therapy
CA2468309A1 (en) 2001-12-26 2003-07-17 Robert Petrosenko Wound vacuum therapy dressing kit
WO2003057071A2 (en) 2001-12-26 2003-07-17 Hill-Rom Services, Inc. Vacuum bandage packing
CA2468912A1 (en) 2001-12-26 2003-07-17 Hill-Rom Services, Inc. Vented vacuum bandage and method
US7338482B2 (en) 2002-02-28 2008-03-04 Hill-Rom Services, Inc. External catheter access to vacuum bandage
US8168848B2 (en) 2002-04-10 2012-05-01 KCI Medical Resources, Inc. Access openings in vacuum bandage
EP2650027B1 (en) * 2002-05-31 2017-09-20 KCI Medical Resources Wound treatment apparatus
US7896856B2 (en) 2002-08-21 2011-03-01 Robert Petrosenko Wound packing for preventing wound closure
US7846141B2 (en) 2002-09-03 2010-12-07 Bluesky Medical Group Incorporated Reduced pressure treatment system
US7815616B2 (en) 2002-09-16 2010-10-19 Boehringer Technologies, L.P. Device for treating a wound
US7625362B2 (en) 2003-09-16 2009-12-01 Boehringer Technologies, L.P. Apparatus and method for suction-assisted wound healing
EP1556125B1 (en) * 2002-10-23 2006-08-23 Coloplast A/S Coupling device
GB0224986D0 (en) 2002-10-28 2002-12-04 Smith & Nephew Apparatus
US7976519B2 (en) * 2002-12-31 2011-07-12 Kci Licensing, Inc. Externally-applied patient interface system and method
US7942866B2 (en) 2003-08-28 2011-05-17 Boehringer Technologies, L.P. Device for treating a wound
US7361184B2 (en) 2003-09-08 2008-04-22 Joshi Ashok V Device and method for wound therapy
US11298453B2 (en) 2003-10-28 2022-04-12 Smith & Nephew Plc Apparatus and method for wound cleansing with actives
GB0325129D0 (en) 2003-10-28 2003-12-03 Smith & Nephew Apparatus in situ
US7128735B2 (en) 2004-01-02 2006-10-31 Richard Scott Weston Reduced pressure wound treatment appliance
US8100887B2 (en) 2004-03-09 2012-01-24 Bluesky Medical Group Incorporated Enclosure-based reduced pressure treatment system
US10058642B2 (en) 2004-04-05 2018-08-28 Bluesky Medical Group Incorporated Reduced pressure treatment system
US7776028B2 (en) 2004-04-05 2010-08-17 Bluesky Medical Group Incorporated Adjustable overlay reduced pressure wound treatment system
US7909805B2 (en) 2004-04-05 2011-03-22 Bluesky Medical Group Incorporated Flexible reduced pressure treatment appliance
US8062272B2 (en) 2004-05-21 2011-11-22 Bluesky Medical Group Incorporated Flexible reduced pressure treatment appliance
US7708724B2 (en) 2004-04-05 2010-05-04 Blue Sky Medical Group Incorporated Reduced pressure wound cupping treatment system
US8529548B2 (en) 2004-04-27 2013-09-10 Smith & Nephew Plc Wound treatment apparatus and method
US10413644B2 (en) 2004-04-27 2019-09-17 Smith & Nephew Plc Wound treatment apparatus and method
GB0409446D0 (en) 2004-04-28 2004-06-02 Smith & Nephew Apparatus
US7753894B2 (en) 2004-04-27 2010-07-13 Smith & Nephew Plc Wound cleansing apparatus with stress
CA2567278A1 (en) * 2004-05-17 2005-12-08 Applied Tissue Technologies, Llc Wound chamber with remote access portal
US7998125B2 (en) 2004-05-21 2011-08-16 Bluesky Medical Group Incorporated Hypobaric chamber treatment system
US7485112B2 (en) 2004-11-08 2009-02-03 Boehringer Technologies, L.P. Tube attachment device for wound treatment
DE202004018245U1 (de) * 2004-11-24 2005-07-07 Riesinger, Birgit Drainagevorrichtung zur Wundbehandlung unter Einsatz von Unterdruck
US7438705B2 (en) 2005-07-14 2008-10-21 Boehringer Technologies, L.P. System for treating a wound with suction and method detecting loss of suction
US7857806B2 (en) 2005-07-14 2010-12-28 Boehringer Technologies, L.P. Pump system for negative pressure wound therapy
WO2007013049A1 (en) 2005-07-24 2007-02-01 Carmeli Adahan Wound closure and drainage system
US7569742B2 (en) 2005-09-07 2009-08-04 Tyco Healthcare Group Lp Self contained wound dressing with micropump
EP1986718B1 (en) * 2006-02-06 2015-10-28 KCI Licensing, Inc. Systems for improved connection to wound dressings in conjunction with reduced pressure wound treatment systems
AU2015210406B2 (en) * 2006-02-06 2018-03-01 Solventum Intellectual Properties Company Systems and methods for improved connection to wound dressings in conjunction with reduced pressure wound treatment systems
GB0604952D0 (en) * 2006-03-13 2006-04-19 Renishaw Plc A fluid connector for fluid delivery apparatus
JP4943497B2 (ja) 2006-03-14 2012-05-30 ケーシーアイ ライセンシング インコーポレイテッド 減圧組織治療中に減圧装置をパージするシステムおよび方法
US8002313B2 (en) * 2006-04-25 2011-08-23 Kci Licensing, Inc. Inline swivel connection for multi-lumen tubing
US7779625B2 (en) 2006-05-11 2010-08-24 Kalypto Medical, Inc. Device and method for wound therapy
US7615036B2 (en) 2006-05-11 2009-11-10 Kalypto Medical, Inc. Device and method for wound therapy
WO2007142688A1 (en) 2006-06-02 2007-12-13 Bengtson Bradley P Assemblies, systems, and methods for vacuum assisted internal drainage during wound healing
US8551075B2 (en) 2006-06-02 2013-10-08 Kci Medical Resources Assemblies, systems, and methods for vacuum assisted internal drainage during wound healing
WO2007143179A2 (en) 2006-06-02 2007-12-13 Bengtson Bradley P Assemblies, systems, and methods for vacuum assisted internal drainage during wound healing
GB0712735D0 (en) * 2006-07-26 2007-08-08 Smith & Nephew Dressing
CN101557853B (zh) * 2006-07-26 2013-03-27 蓝天医疗集团有限公司 敷料
US9539373B2 (en) 2006-08-30 2017-01-10 Southeastern Medical Technologies, Llc Methods, compositions and apparatuses to treat wounds with pressures altered from atmospheric
US8366690B2 (en) 2006-09-19 2013-02-05 Kci Licensing, Inc. System and method for determining a fill status of a canister of fluid in a reduced pressure treatment system
EP2063787B8 (en) 2006-09-19 2017-08-16 KCI Licensing, Inc. Reduced pressure treatment system having blockage clearing and dual-zone pressure protection capabilities
US8061360B2 (en) 2006-09-19 2011-11-22 Kci Licensing, Inc. System and method for locating fluid leaks at a drape of a reduced pressure delivery system
US9820888B2 (en) 2006-09-26 2017-11-21 Smith & Nephew, Inc. Wound dressing
US8641691B2 (en) 2006-09-28 2014-02-04 Smith & Nephew, Inc. Portable wound therapy system
EP2081618B1 (en) 2006-10-13 2016-01-06 Bluesky Medical Group Inc. Improved control circuit and apparatus for negative pressure wound treatment
AU2007311028B2 (en) 2006-10-17 2013-06-27 Smith & Nephew Plc Auxiliary powered negative pressure wound therapy apparatuses and methods
US7931651B2 (en) 2006-11-17 2011-04-26 Wake Lake University Health Sciences External fixation assembly and method of use
US8377016B2 (en) 2007-01-10 2013-02-19 Wake Forest University Health Sciences Apparatus and method for wound treatment employing periodic sub-atmospheric pressure
US20100218834A1 (en) * 2007-01-30 2010-09-02 Diramo A/S Micro fluid device with a multi lumen hose
AU2012202494B2 (en) * 2007-02-09 2015-01-15 Kci Licensing Inc. Apparatus and method for administering reduced pressure treatment to a tissue site
AU2008216787B2 (en) 2007-02-09 2012-03-08 Solventum Intellectual Properties Company Apparatus and method for administering reduced pressure treatment to a tissue site
US8057447B2 (en) 2007-05-10 2011-11-15 Kci Licensing Inc. Reduced pressure wound dressing having a wound contact surface with columnar protrusions
EP2146774B2 (de) 2007-05-22 2018-08-22 Medela Holding AG Drainageschlaucheinheit
WO2008154158A2 (en) 2007-05-24 2008-12-18 Applied Tissue Technologies Llc Woundtreatment device employing negative pressure
US8070189B2 (en) * 2007-06-20 2011-12-06 Carefusion 303, Inc. Safety luer connection
US9408954B2 (en) 2007-07-02 2016-08-09 Smith & Nephew Plc Systems and methods for controlling operation of negative pressure wound therapy apparatus
GB0715259D0 (en) 2007-08-06 2007-09-12 Smith & Nephew Canister status determination
CN101896140B (zh) 2007-10-10 2014-01-08 韦克福里斯特大学健康科学院 用于治疗脊髓组织的装置和方法
EP3590480B1 (en) 2007-10-11 2023-05-03 3M Innovative Properties Company Closed incision negative pressure wound therapy device
AU2008327660B2 (en) 2007-11-21 2014-02-13 Smith & Nephew Plc Wound dressing
GB0722820D0 (en) 2007-11-21 2008-01-02 Smith & Nephew Vacuum assisted wound dressing
HUE041864T2 (hu) 2007-11-21 2019-06-28 Smith & Nephew Sebkötözõ
EP2065086B1 (en) 2007-11-29 2014-07-30 Corning Incorporated Microreactor with a fluid input or output porting assembly
WO2009068665A1 (en) * 2007-11-30 2009-06-04 Coloplast A/S Tube assembly for use in a wound drainage system
GB0723872D0 (en) 2007-12-06 2008-01-16 Smith & Nephew Apparatus for topical negative pressure therapy
US8545467B2 (en) 2007-12-07 2013-10-01 Medela Holding Ag Wound cover connecting device
US8377017B2 (en) * 2008-01-03 2013-02-19 Kci Licensing, Inc. Low-profile reduced pressure treatment system
WO2009086580A1 (en) * 2008-01-07 2009-07-16 Cerulean Medical Pty Ltd Negative pressure treatment device
US9033942B2 (en) 2008-03-07 2015-05-19 Smith & Nephew, Inc. Wound dressing port and associated wound dressing
US8021347B2 (en) 2008-07-21 2011-09-20 Tyco Healthcare Group Lp Thin film wound dressing
US8298200B2 (en) 2009-06-01 2012-10-30 Tyco Healthcare Group Lp System for providing continual drainage in negative pressure wound therapy
KR20100129763A (ko) * 2008-03-13 2010-12-09 케이씨아이 라이센싱 인코포레이티드 부하제거 및 감압 치료 시스템 및 방법
US20090281509A1 (en) * 2008-05-12 2009-11-12 Gellis Michael B Apparatus to collect body fluids following liposuction surgery
JP5290405B2 (ja) * 2008-05-13 2013-09-18 ケーシーアイ ライセンシング インコーポレイテッド カテーテル/フィラメント型装置および皮膚表面下の傷を治療する方法
CN103977459B (zh) 2008-05-30 2017-09-05 凯希特许有限公司 减压线形创伤闭合垫枕和系统
CN102036700B (zh) 2008-05-30 2014-07-16 凯希特许有限公司 用于使用减压的创伤处理的敷料组件
CA3004987A1 (en) 2008-07-18 2010-01-21 Wake Forest University Health Sciences Apparatus and method for cardiac tissue modulation by topical application of vacuum to minimize cell death and damage
NO2309961T3 (zh) 2008-08-08 2018-05-05
MX2011002861A (es) 2008-09-18 2011-04-26 Kci Licensing Inc Sistemas y metodos para el suministro de terapia.
CA2741446C (en) 2008-10-29 2017-12-19 Tyler Simmons Medical canister connectors
EP2623137B2 (en) 2008-10-29 2022-06-08 KCI Licensing, Inc. Reduced pressure wound closure systems
KR101028916B1 (ko) * 2008-11-12 2011-04-12 주식회사 대웅제약 의료용 흡입장치
US20100150991A1 (en) * 2008-12-15 2010-06-17 Bernstein Brent H Combination Wound Therapy
US8162907B2 (en) 2009-01-20 2012-04-24 Tyco Healthcare Group Lp Method and apparatus for bridging from a dressing in negative pressure wound therapy
GB0902368D0 (en) 2009-02-13 2009-04-01 Smith & Nephew Wound packing
GB0902816D0 (en) 2009-02-19 2009-04-08 Smith & Nephew Fluid communication path
CA2757841C (en) 2009-04-10 2018-06-12 Spiracur, Inc. Methods and devices for applying closed incision negative pressure wound therapy
US8444614B2 (en) 2009-04-10 2013-05-21 Spiracur, Inc. Methods and devices for applying closed incision negative pressure wound therapy
EP2419157A4 (en) 2009-04-17 2018-01-03 Kalypto Medical, Inc. Negative pressure wound therapy device
CH700975A1 (de) * 2009-05-08 2010-11-15 Medela Holding Ag Drainageschlauchvorrichtung und kuppelungseinheit.
DE102009025004A1 (de) * 2009-06-16 2011-01-20 Vcs Medical Technology Gmbh Druckmessung im Abzweigschlauch
US20100324516A1 (en) 2009-06-18 2010-12-23 Tyco Healthcare Group Lp Apparatus for Vacuum Bridging and/or Exudate Collection
TW201102116A (en) * 2009-07-13 2011-01-16 Univ Nat Pingtung Sci & Tech A portable negative-bias caring device
DE102009038130A1 (de) * 2009-08-12 2011-02-17 ATMOS Medizin Technik GmbH & Co. KG Am Körper eines Benutzers tragbare Vorrichtung zur Bereitstellung von Unterdruck für medizinische Anwendungen
KR200456425Y1 (ko) 2009-08-14 2011-10-31 주식회사 바이오알파 흡인기용 연결기구
DK2515961T3 (da) 2009-12-22 2019-07-15 Smith & Nephew Inc Apparatuses and methods for negative pressure wound therapy
JP6062247B2 (ja) * 2010-01-20 2017-01-18 ケーシーアイ ライセンシング インク 流体潅流および陰圧治療のための接続パッド
EP2539013B1 (en) * 2010-02-23 2018-04-04 L-Vad Technology Inc. Vacuum assisted percutaneous appliance
US8791315B2 (en) 2010-02-26 2014-07-29 Smith & Nephew, Inc. Systems and methods for using negative pressure wound therapy to manage open abdominal wounds
US8821458B2 (en) * 2010-04-16 2014-09-02 Kci Licensing, Inc. Evaporative body-fluid containers and methods
US9061095B2 (en) 2010-04-27 2015-06-23 Smith & Nephew Plc Wound dressing and method of use
GB201006986D0 (en) 2010-04-27 2010-06-09 Smith & Nephew Wound dressing
USRE48117E1 (en) 2010-05-07 2020-07-28 Smith & Nephew, Inc. Apparatuses and methods for negative pressure wound therapy
DE202010013431U1 (de) 2010-05-31 2010-11-25 ORTHOS Orthopädietechnik GmbH Medizinisches Gerät zur Verbesserung des Wundheilungsprozesses
FR2961886B1 (fr) * 2010-06-23 2012-08-10 Braun Medical Sas Systeme de raccord a deux pieces destine a un tuyau a deux lumieres
US8690845B2 (en) 2010-07-16 2014-04-08 Kci Licensing, Inc. System and method for interfacing with a reduced pressure dressing
DE102010034292A1 (de) 2010-08-13 2012-02-16 Paul Hartmann Ag Verbindungsvorrichtung zum Zusammenführen wenigstens zweier Leitungsabschnitte bei einem Unterdruckwundbehandlungssystem
US8986269B2 (en) * 2010-11-11 2015-03-24 Ulcerx Medical Inc. Wound leakage vacuum collection device
JP5715383B2 (ja) * 2010-11-18 2015-05-07 学校法人 久留米大学 陰圧創傷治療装置
JP6241877B2 (ja) 2010-12-01 2017-12-06 ダニエル・エデュアード・クライナー 管腔内減圧療法に使用される器具
WO2012087376A1 (en) 2010-12-22 2012-06-28 Smith & Nephew, Inc. Apparatuses and methods for negative pressure wound therapy
USD714433S1 (en) 2010-12-22 2014-09-30 Smith & Nephew, Inc. Suction adapter
DE102011009241A1 (de) * 2011-01-14 2012-07-19 ATMOS Medizin Technik GmbH & Co. KG Saugleitung für eine Unterdruckwundbehandlungseinrichtung mit Steckverbinderteilen
US9421132B2 (en) 2011-02-04 2016-08-23 University Of Massachusetts Negative pressure wound closure device
EP3932327A1 (en) 2011-02-04 2022-01-05 University Of Massachusetts Negative pressure wound closure device
US20120253302A1 (en) * 2011-04-04 2012-10-04 Tyco Healthcare Group Lp Negative Pressure Wound Therapy Dressing
US9058634B2 (en) 2011-05-24 2015-06-16 Kalypto Medical, Inc. Method for providing a negative pressure wound therapy pump device
CA2837181A1 (en) 2011-05-24 2012-11-29 Kalypto Medical, Inc. Device with controller and pump modules for providing negative pressure for wound therapy
US9067003B2 (en) 2011-05-26 2015-06-30 Kalypto Medical, Inc. Method for providing negative pressure to a negative pressure wound therapy bandage
EP2599518A1 (en) * 2011-11-30 2013-06-05 Fresenius Medical Care Deutschland GmbH Connector with double lumen tube
US9636493B2 (en) 2012-05-08 2017-05-02 Fenwal, Inc. Multi-lumen tubing to single lumen tubing connector
CA2874392A1 (en) 2012-05-22 2013-11-28 Smith & Nephew Plc Apparatuses and methods for wound therapy
AU2013291693B2 (en) 2012-05-22 2018-03-01 Smith & Nephew Plc Wound closure device
US9907703B2 (en) 2012-05-23 2018-03-06 Smith & Nephew Plc Apparatuses and methods for negative pressure wound therapy
EP3470029A1 (en) 2012-05-24 2019-04-17 Smith & Nephew, Inc. Devices for treating and closing wounds with negative pressure
JP6230166B2 (ja) 2012-06-03 2017-11-15 ダニエル・エデュアード・クレイナー 管腔内陰圧治療デバイス
DK2674186T3 (da) * 2012-06-11 2022-03-21 Freudenberg Carl Kg Fisteladapteranordning
BR112015000890A2 (pt) 2012-07-16 2017-06-27 Smith & Nephew Inc dispositivo de fechamento de ferida por pressão negativa
AU2013298195B2 (en) 2012-08-01 2017-07-13 Smith & Nephew Plc Wound dressing
AU2013298198B2 (en) 2012-08-01 2017-05-11 Smith & Nephew Plc Wound dressing
US9510946B2 (en) 2012-09-06 2016-12-06 Edwards Lifesciences Corporation Heart valve sealing devices
JP6407954B2 (ja) 2013-03-13 2018-10-17 スミス アンド ネフュー インコーポレイテッド 陰圧創傷閉鎖デバイスおよびシステムならびに陰圧による創傷治療での使用方法
EP2968015B1 (en) 2013-03-14 2018-05-16 Smith & Nephew PLC Compressible wound fillers and systems and methods of use in treating wounds with negative pressure
WO2014158526A1 (en) * 2013-03-14 2014-10-02 Kci Licensing, Inc. Negative pressure therapy with dynamic profile capability
BR112015020855A2 (pt) 2013-03-15 2017-07-18 Smith & Nephew curativo para ferida e método de tratamento
EP2783724B1 (en) * 2013-03-28 2018-10-17 Dentsply IH AB Catheter coupling arrangement
EP3677291B1 (en) 2013-05-10 2024-01-03 Smith & Nephew PLC Fluidic connector for irrigation and aspiration of wounds
CN103285496B (zh) * 2013-05-22 2015-10-21 苏州爱得科技发展有限公司 多点负压引流装置
CA2926470C (en) 2013-10-21 2023-03-14 Smith & Nephew, Inc. Negative pressure wound closure device
MX2016009477A (es) 2014-01-21 2016-10-13 Smith & Nephew Vendaje plegable para el tratamiento de heridas con presion negativa.
DE102014013419A1 (de) * 2014-09-10 2016-03-10 Fresenius Medical Care Deutschland Gmbh Vorrichtung umfassend einen mehrlumigen Schlauch
US10441739B1 (en) * 2015-03-17 2019-10-15 Michael Golub Multi-functional device having an interchangeable option for a spring-loaded valve for delivering inhaling medical gas and/or nebulized medicine to a spontaneously breathing patient
JP2018513720A (ja) 2015-03-18 2018-05-31 プラキャス メディカル インコーポレイテッド 紫外線殺菌のためのカテーテル接続システム
CN104815358B (zh) * 2015-04-23 2018-06-12 广州新诚生物科技有限公司 可实现自循环的负压引流系统
CN104815385A (zh) * 2015-04-23 2015-08-05 广州新诚生物科技有限公司 多功能负压引流系统
US11439539B2 (en) 2015-04-29 2022-09-13 University Of Massachusetts Negative pressure wound closure device
US10076594B2 (en) 2015-05-18 2018-09-18 Smith & Nephew Plc Fluidic connector for negative pressure wound therapy
EP3117868B1 (de) * 2015-07-16 2023-11-01 Lohmann & Rauscher GmbH Anschlussvorrichtung für die wundversorgung und wundversorgungskit
US20170028111A1 (en) 2015-07-29 2017-02-02 Innovative Therapies, Inc. Wound therapy device pressure monitoring and control system
US10814049B2 (en) 2015-12-15 2020-10-27 University Of Massachusetts Negative pressure wound closure devices and methods
US11471586B2 (en) 2015-12-15 2022-10-18 University Of Massachusetts Negative pressure wound closure devices and methods
US10575991B2 (en) 2015-12-15 2020-03-03 University Of Massachusetts Negative pressure wound closure devices and methods
USD837977S1 (en) 2016-04-07 2019-01-08 Coloplast A/S Replacement tubing with connectors adapted for use in anal irrigation system
USD828550S1 (en) 2016-04-07 2018-09-11 Coloplast A/S Connector of an anal irrigation system
USD817483S1 (en) 2016-04-07 2018-05-08 Coloplast A/S Anal irrigation catheter adapted for use in an anal irrigation system
WO2018013572A1 (en) * 2016-07-11 2018-01-18 Puracath Medical, Inc. Catheter connection system for ultraviolet light disinfection
EP3573677A2 (en) * 2017-01-27 2019-12-04 KCI Licensing, Inc. Multi-layer abdominal closure dressing with instillation capabilities
EP3644914A1 (en) 2017-06-30 2020-05-06 T J Smith & Nephew Limited Negative pressure wound therapy apparatus
EP3461388A1 (en) * 2017-09-28 2019-04-03 Koninklijke Philips N.V. Optical connection device and method
GB201718014D0 (en) 2017-11-01 2017-12-13 Smith & Nephew Dressing for negative pressure wound therapy with filter
US10894137B2 (en) * 2017-12-20 2021-01-19 Primed Halberstadt Medizintechnik Gmbh Tracheal tube and method of production
WO2019157466A1 (en) 2018-02-12 2019-08-15 Healyx Labs, Inc. Negative pressure wound therapy systems, devices, and methods
GB201811449D0 (en) 2018-07-12 2018-08-29 Smith & Nephew Apparatuses and methods for negative pressure wound therapy
MX2021003118A (es) * 2018-09-19 2021-08-19 Deroyal Ind Inc Sistema de conexión de tubos para terapia de heridas con presión negativa.
DE202018105593U1 (de) * 2018-09-28 2018-10-25 Lohmann & Rauscher Gmbh Verbindungsvorrichtung für die Wundversorgung und Wundversorgungskit
US20220020982A1 (en) * 2018-11-13 2022-01-20 Iucf-Hyu (Industry-University Cooperation Foundation Hanyang University) Cathode active material and lithium secondary battery comprising same
CN112972792B (zh) * 2021-02-24 2023-06-06 西南医科大学 一种儿科负压智能化控制洗胃装置

Family Cites Families (142)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1355846A (en) 1920-02-06 1920-10-19 David A Rannells Medical appliance
FR711568A (fr) * 1930-03-03 1931-09-12 Gas Light & Coke Co Perfectionnements aux tubes flexibles, tels que les tubes en caoutchouc et matière analogue
US2547758A (en) 1949-01-05 1951-04-03 Wilmer B Keeling Instrument for treating the male urethra
US2632443A (en) 1949-04-18 1953-03-24 Eleanor P Lesher Surgical dressing
GB692578A (en) 1949-09-13 1953-06-10 Minnesota Mining & Mfg Improvements in or relating to drape sheets for surgical use
US2682873A (en) 1952-07-30 1954-07-06 Johnson & Johnson General purpose protective dressing
NL189176B (nl) 1956-07-13 1900-01-01 Hisamitsu Pharmaceutical Co Pleister op basis van een synthetische rubber.
US2969057A (en) 1957-11-04 1961-01-24 Brady Co W H Nematodic swab
US3066672A (en) 1960-09-27 1962-12-04 Jr William H Crosby Method and apparatus for serial sampling of intestinal juice
US3367332A (en) 1965-08-27 1968-02-06 Gen Electric Product and process for establishing a sterile area of skin
US3520300A (en) 1967-03-15 1970-07-14 Amp Inc Surgical sponge and suction device
US3568675A (en) 1968-08-30 1971-03-09 Clyde B Harvey Fistula and penetrating wound dressing
CH537552A (fr) * 1970-03-13 1973-05-31 Ipp Ind Polymer Proc S A Dispositif terminal pour conduite pour fluides
US3682180A (en) 1970-06-08 1972-08-08 Coilform Co Inc Drain clip for surgical drain
BE789293Q (fr) 1970-12-07 1973-01-15 Parke Davis & Co Pansement medico-chirugical pour brulures et lesions analogues
US3826254A (en) 1973-02-26 1974-07-30 Verco Ind Needle or catheter retaining appliance
DE2527706A1 (de) 1975-06-21 1976-12-30 Hanfried Dr Med Weigand Einrichtung zum einleiten von kontrastmittel in einen kuenstlichen darmausgang
DE2640413C3 (de) 1976-09-08 1980-03-27 Richard Wolf Gmbh, 7134 Knittlingen Katheter-Überwachungsgerät
NL7710909A (nl) 1976-10-08 1978-04-11 Smith & Nephew Samengestelde hechtstrook.
GB1562244A (en) 1976-11-11 1980-03-05 Lock P M Wound dressing materials
US4080970A (en) 1976-11-17 1978-03-28 Miller Thomas J Post-operative combination dressing and internal drain tube with external shield and tube connector
US4139004A (en) 1977-02-17 1979-02-13 Gonzalez Jr Harry Bandage apparatus for treating burns
US4184510A (en) 1977-03-15 1980-01-22 Fibra-Sonics, Inc. Valued device for controlling vacuum in surgery
US4165748A (en) 1977-11-07 1979-08-28 Johnson Melissa C Catheter tube holder
US4245637A (en) 1978-07-10 1981-01-20 Nichols Robert L Shutoff valve sleeve
SE414994B (sv) 1978-11-28 1980-09-01 Landstingens Inkopscentral Venkateterforband
GB2047543B (en) 1978-12-06 1983-04-20 Svedman Paul Device for treating tissues for example skin
US4266545A (en) 1979-04-06 1981-05-12 Moss James P Portable suction device for collecting fluids from a closed wound
US4284079A (en) 1979-06-28 1981-08-18 Adair Edwin Lloyd Method for applying a male incontinence device
US4261363A (en) 1979-11-09 1981-04-14 C. R. Bard, Inc. Retention clips for body fluid drains
US4569348A (en) 1980-02-22 1986-02-11 Velcro Usa Inc. Catheter tube holder strap
EP0035583B1 (de) 1980-03-11 1985-08-14 Schmid, Eduard, Dr.Dr.med. Hauttransplantations-Druckverband
US4297995A (en) 1980-06-03 1981-11-03 Key Pharmaceuticals, Inc. Bandage containing attachment post
US4333468A (en) 1980-08-18 1982-06-08 Geist Robert W Mesentery tube holder apparatus
US4465485A (en) 1981-03-06 1984-08-14 Becton, Dickinson And Company Suction canister with unitary shut-off valve and filter features
US4392853A (en) 1981-03-16 1983-07-12 Rudolph Muto Sterile assembly for protecting and fastening an indwelling device
US4373519A (en) 1981-06-26 1983-02-15 Minnesota Mining And Manufacturing Company Composite wound dressing
US4392858A (en) 1981-07-16 1983-07-12 Sherwood Medical Company Wound drainage device
US4419097A (en) 1981-07-31 1983-12-06 Rexar Industries, Inc. Attachment for catheter tube
AU550575B2 (en) 1981-08-07 1986-03-27 Richard Christian Wright Wound drainage device
SE429197B (sv) 1981-10-14 1983-08-22 Frese Nielsen Anordning for behandling av sar
DE3146266A1 (de) 1981-11-21 1983-06-01 B. Braun Melsungen Ag, 3508 Melsungen Kombinierte vorrichtung fuer eine medizinische saugdrainage
US4551139A (en) 1982-02-08 1985-11-05 Marion Laboratories, Inc. Method and apparatus for burn wound treatment
US4475909A (en) 1982-05-06 1984-10-09 Eisenberg Melvin I Male urinary device and method for applying the device
DE3361779D1 (en) 1982-07-06 1986-02-20 Dow Corning Medical-surgical dressing and a process for the production thereof
NZ206837A (en) 1983-01-27 1986-08-08 Johnson & Johnson Prod Inc Thin film adhesive dressing:backing material in three sections
US4548202A (en) 1983-06-20 1985-10-22 Ethicon, Inc. Mesh tissue fasteners
US4540412A (en) 1983-07-14 1985-09-10 The Kendall Company Device for moist heat therapy
US4543100A (en) 1983-11-01 1985-09-24 Brodsky Stuart A Catheter and drain tube retainer
US4525374A (en) 1984-02-27 1985-06-25 Manresa, Inc. Treating hydrophobic filters to render them hydrophilic
GB2157958A (en) 1984-05-03 1985-11-06 Ernest Edward Austen Bedding Ball game net support
US4551130A (en) * 1984-05-08 1985-11-05 Herbert William B Surgical drainage and irrigation apparatus for post operative patient care
US4897081A (en) 1984-05-25 1990-01-30 Thermedics Inc. Percutaneous access device
US5215522A (en) 1984-07-23 1993-06-01 Ballard Medical Products Single use medical aspirating device and method
GB8419745D0 (en) 1984-08-02 1984-09-05 Smith & Nephew Ass Wound dressing
US4872450A (en) 1984-08-17 1989-10-10 Austad Eric D Wound dressing and method of forming same
US4826494A (en) 1984-11-09 1989-05-02 Stryker Corporation Vacuum wound drainage system
US4655754A (en) 1984-11-09 1987-04-07 Stryker Corporation Vacuum wound drainage system and lipids baffle therefor
US4605399A (en) 1984-12-04 1986-08-12 Complex, Inc. Transdermal infusion device
US4701159A (en) * 1984-12-05 1987-10-20 I-Flow Corporation Multilumen catheter set
US5037397A (en) 1985-05-03 1991-08-06 Medical Distributors, Inc. Universal clamp
US4640688A (en) 1985-08-23 1987-02-03 Mentor Corporation Urine collection catheter
US4710165A (en) 1985-09-16 1987-12-01 Mcneil Charles B Wearable, variable rate suction/collection device
US4758220A (en) 1985-09-26 1988-07-19 Alcon Laboratories, Inc. Surgical cassette proximity sensing and latching apparatus
US4733659A (en) 1986-01-17 1988-03-29 Seton Company Foam bandage
EP0256060A1 (en) 1986-01-31 1988-02-24 OSMOND, Roger L. W. Suction system for wound and gastro-intestinal drainage
US4838883A (en) 1986-03-07 1989-06-13 Nissho Corporation Urine-collecting device
JPS62281965A (ja) 1986-05-29 1987-12-07 テルモ株式会社 カテ−テルおよびカテ−テル用固定部材
GB8621884D0 (en) 1986-09-11 1986-10-15 Bard Ltd Catheter applicator
GB2195255B (en) 1986-09-30 1991-05-01 Vacutec Uk Limited Apparatus for vacuum treatment of an epidermal surface
US4743232A (en) 1986-10-06 1988-05-10 The Clinipad Corporation Package assembly for plastic film bandage
DE3634569A1 (de) 1986-10-10 1988-04-21 Sachse Hans E Kondomkatheter, ein harnroehrenkatheter zur verhinderung von aufsteigenden infektionen
US4796615A (en) * 1986-10-16 1989-01-10 Baxter Travenol Laboratories, Inc. Connector for esophageal probe
JPS63135179A (ja) 1986-11-26 1988-06-07 立花 俊郎 薬物の経皮投与具
GB8628564D0 (en) 1986-11-28 1987-01-07 Smiths Industries Plc Anti-foaming agent suction apparatus
JPH0433259Y2 (zh) 1987-01-27 1992-08-10
GB8706116D0 (en) 1987-03-14 1987-04-15 Smith & Nephew Ass Adhesive dressings
USD303712S (en) * 1987-04-01 1989-09-26 Goldberg Harvey W Catheter connector for drainage tubes
US4787888A (en) 1987-06-01 1988-11-29 University Of Connecticut Disposable piezoelectric polymer bandage for percutaneous delivery of drugs and method for such percutaneous delivery (a)
US4863449A (en) 1987-07-06 1989-09-05 Hollister Incorporated Adhesive-lined elastic condom cathether
US5176663A (en) 1987-12-02 1993-01-05 Pal Svedman Dressing having pad with compressibility limiting elements
US4826949A (en) 1987-12-22 1989-05-02 Basf Corporation High shrinkage polyester fibers and method of preparation
US4906240A (en) 1988-02-01 1990-03-06 Matrix Medica, Inc. Adhesive-faced porous absorbent sheet and method of making same
US4985019A (en) 1988-03-11 1991-01-15 Michelson Gary K X-ray marker
GB8812803D0 (en) 1988-05-28 1988-06-29 Smiths Industries Plc Medico-surgical containers
US4919654A (en) 1988-08-03 1990-04-24 Kalt Medical Corporation IV clamp with membrane
US5000741A (en) 1988-08-22 1991-03-19 Kalt Medical Corporation Transparent tracheostomy tube dressing
JPH02270874A (ja) 1989-01-16 1990-11-05 Roussel Uclaf アザビシクロ化合物及びそれらの塩、それらの製造方法、それらを含有する製薬組成物並びにそれらの薬剤としての使用
GB8906100D0 (en) 1989-03-16 1989-04-26 Smith & Nephew Laminates
US4969880A (en) 1989-04-03 1990-11-13 Zamierowski David S Wound dressing and treatment method
US5527293A (en) 1989-04-03 1996-06-18 Kinetic Concepts, Inc. Fastening system and method
US5100396A (en) 1989-04-03 1992-03-31 Zamierowski David S Fluidic connection system and method
US5261893A (en) 1989-04-03 1993-11-16 Zamierowski David S Fastening system and method
JP2719671B2 (ja) 1989-07-11 1998-02-25 日本ゼオン株式会社 創傷被覆材
US5358494A (en) 1989-07-11 1994-10-25 Svedman Paul Irrigation dressing
US5232453A (en) 1989-07-14 1993-08-03 E. R. Squibb & Sons, Inc. Catheter holder
GB2235877A (en) 1989-09-18 1991-03-20 Antonio Talluri Closed wound suction apparatus
US5134994A (en) 1990-02-12 1992-08-04 Say Sam L Field aspirator in a soft pack with externally mounted container
US5092858A (en) 1990-03-20 1992-03-03 Becton, Dickinson And Company Liquid gelling agent distributor device
US5029580A (en) * 1990-07-18 1991-07-09 Ballard Medical Products Medical aspirating apparatus with multi-lumen catheter tube and methods
US5149331A (en) 1991-05-03 1992-09-22 Ariel Ferdman Method and device for wound closure
US5278100A (en) 1991-11-08 1994-01-11 Micron Technology, Inc. Chemical vapor deposition technique for depositing titanium silicide on semiconductor wafers
US5645081A (en) 1991-11-14 1997-07-08 Wake Forest University Method of treating tissue damage and apparatus for same
US5636643A (en) 1991-11-14 1997-06-10 Wake Forest University Wound treatment employing reduced pressure
US5279550A (en) 1991-12-19 1994-01-18 Gish Biomedical, Inc. Orthopedic autotransfusion system
RU2051693C1 (ru) 1992-01-22 1996-01-10 Лебедев Александр Николаевич Устройство для отсоса патологического содержимого при воспалительном процессе пальца руки
US5167613A (en) 1992-03-23 1992-12-01 The Kendall Company Composite vented wound dressing
FR2690617B1 (fr) 1992-04-29 1994-06-24 Cbh Textile Pansement adhesif transparent.
DE4306478A1 (de) 1993-03-02 1994-09-08 Wolfgang Dr Wagner Drainagevorrichtung, insbesondere Pleuradrainagevorrichtung, und Drainageverfahren
GB9307312D0 (en) 1993-04-07 1993-06-02 United Surgical Services Ltd Surgical wound dressings
US6241747B1 (en) 1993-05-03 2001-06-05 Quill Medical, Inc. Barbed Bodily tissue connector
US5342376A (en) 1993-05-03 1994-08-30 Dermagraphics, Inc. Inserting device for a barbed tissue connector
US5344415A (en) 1993-06-15 1994-09-06 Deroyal Industries, Inc. Sterile system for dressing vascular access site
US5437651A (en) 1993-09-01 1995-08-01 Research Medical, Inc. Medical suction apparatus
US5549584A (en) 1994-02-14 1996-08-27 The Kendall Company Apparatus for removing fluid from a wound
US5607388A (en) 1994-06-16 1997-03-04 Hercules Incorporated Multi-purpose wound dressing
US5556375A (en) 1994-06-16 1996-09-17 Hercules Incorporated Wound dressing having a fenestrated base layer
US5664270A (en) 1994-07-19 1997-09-09 Kinetic Concepts, Inc. Patient interface system
DK0853950T3 (da) 1994-08-22 2002-11-25 Kinetic Concepts Inc Sårdrainagekanister
US5588958A (en) * 1994-09-21 1996-12-31 C. R. Bard, Inc. Closed wound orthopaedic drainage and autotransfusion system
US5496299A (en) * 1994-09-21 1996-03-05 C. R. Bard, Inc. Suction reservoir
DE29504378U1 (de) 1995-03-15 1995-09-14 Mtg Medizinisch Tech Geraeteba Elektronisch geregelte Niedervakuumpumpe für die Thorax- und Wunddrainage
GB2307130B (en) 1995-11-09 2000-03-08 Sony Uk Ltd Video down-conversion
GB9523253D0 (en) * 1995-11-14 1996-01-17 Mediscus Prod Ltd Portable wound treatment apparatus
US5681063A (en) * 1995-11-28 1997-10-28 E.R. Squibb & Sons, Inc. Connector assembly for double tubing
RU2116088C1 (ru) 1997-03-24 1998-07-27 Российская медицинская академия последипломного образования Министерства здравоохранения Российской Федерации Способ лечения инфицированных ран дистальных отделов нижней конечности
US6135116A (en) 1997-07-28 2000-10-24 Kci Licensing, Inc. Therapeutic method for treating ulcers
GB9719520D0 (en) 1997-09-12 1997-11-19 Kci Medical Ltd Surgical drape and suction heads for wound treatment
AU755496B2 (en) 1997-09-12 2002-12-12 Kci Licensing, Inc. Surgical drape and suction head for wound treatment
US6071267A (en) 1998-02-06 2000-06-06 Kinetic Concepts, Inc. Medical patient fluid management interface system and method
US6488643B1 (en) 1998-10-08 2002-12-03 Kci Licensing, Inc. Wound healing foot wrap
US6287316B1 (en) 1999-03-26 2001-09-11 Ethicon, Inc. Knitted surgical mesh
US6856821B2 (en) 2000-05-26 2005-02-15 Kci Licensing, Inc. System for combined transcutaneous blood gas monitoring and vacuum assisted wound closure
US7799004B2 (en) 2001-03-05 2010-09-21 Kci Licensing, Inc. Negative pressure wound treatment apparatus and infection identification system and method
US6695823B1 (en) * 1999-04-09 2004-02-24 Kci Licensing, Inc. Wound therapy device
US6991643B2 (en) 2000-12-20 2006-01-31 Usgi Medical Inc. Multi-barbed device for retaining tissue in apposition and methods of use
USD431651S (en) * 1999-08-09 2000-10-03 Incutech, Inc. Multi-lumen catheter connector
GB9926538D0 (en) 1999-11-09 2000-01-12 Kci Medical Ltd Multi-lumen connector
JP4129536B2 (ja) 2000-02-24 2008-08-06 ヴェネテック インターナショナル,インコーポレイテッド 高適合性カテーテルアンカリングシステム
US6540705B2 (en) 2001-02-22 2003-04-01 Core Products International, Inc. Ankle brace providing upper and lower ankle adjustment
US6921396B1 (en) * 2002-08-30 2005-07-26 Arrow International, Inc. Multi-lumen catheter with integrated connector
US7976519B2 (en) 2002-12-31 2011-07-12 Kci Licensing, Inc. Externally-applied patient interface system and method

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101257877B (zh) * 2005-06-29 2013-07-17 应用纸巾技术有限公司 伤口敷裹

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WO2001034223A1 (en) 2001-05-17
JP2003513715A (ja) 2003-04-15
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US8740878B2 (en) 2014-06-03
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US7678102B1 (en) 2010-03-16
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