CN1132566C - 在胶囊中填充囊芯的方法和由该方法制得的固体剂型 - Google Patents
在胶囊中填充囊芯的方法和由该方法制得的固体剂型 Download PDFInfo
- Publication number
- CN1132566C CN1132566C CN95196811A CN95196811A CN1132566C CN 1132566 C CN1132566 C CN 1132566C CN 95196811 A CN95196811 A CN 95196811A CN 95196811 A CN95196811 A CN 95196811A CN 1132566 C CN1132566 C CN 1132566C
- Authority
- CN
- China
- Prior art keywords
- capsule
- dosage forms
- solid dosage
- core
- moisture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
- A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
- A61J3/072—Sealing capsules, e.g. rendering them tamper-proof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
- A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
Abstract
Description
Claims (52)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35813794A | 1994-12-16 | 1994-12-16 | |
US08/358,137 | 1994-12-16 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1170346A CN1170346A (zh) | 1998-01-14 |
CN1132566C true CN1132566C (zh) | 2003-12-31 |
Family
ID=23408454
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN95196811A Expired - Lifetime CN1132566C (zh) | 1994-12-16 | 1995-11-09 | 在胶囊中填充囊芯的方法和由该方法制得的固体剂型 |
Country Status (14)
Country | Link |
---|---|
US (1) | US6080426A (zh) |
EP (1) | EP0797424B1 (zh) |
JP (1) | JP3670016B2 (zh) |
KR (1) | KR100468335B1 (zh) |
CN (1) | CN1132566C (zh) |
AT (1) | ATE194486T1 (zh) |
CA (1) | CA2205553C (zh) |
DE (1) | DE69518006T2 (zh) |
DK (1) | DK0797424T3 (zh) |
ES (1) | ES2150017T3 (zh) |
GR (1) | GR3034491T3 (zh) |
MX (1) | MX9703773A (zh) |
PT (1) | PT797424E (zh) |
WO (1) | WO1996018370A1 (zh) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6245350B1 (en) | 1994-12-16 | 2001-06-12 | Warner-Lambert Company | Process for encapsulation of caplets in a capsule and solid dosage forms obtainable by such process |
JP3670016B2 (ja) * | 1994-12-16 | 2005-07-13 | ワーナー−ランバート・カンパニー | カプレットをカプセル内に封入する方法及びかかる方法により得ることができる固体剤形 |
FR2757173A1 (fr) * | 1996-12-17 | 1998-06-19 | Warner Lambert Co | Compositions polymeres d'origine non-animale pour la formation de films |
US6428809B1 (en) * | 1999-08-18 | 2002-08-06 | Microdose Technologies, Inc. | Metering and packaging of controlled release medication |
US20030032675A1 (en) * | 2001-02-15 | 2003-02-13 | Franz G. Andrew | Manufacture of thyroid hormone tablets having consistent active moiety amounts |
US7067148B2 (en) * | 2001-02-15 | 2006-06-27 | King Pharmaceutical Research & Development, Inc. | Stabilized pharmaceutical and thyroid hormone compositions and method of preparation |
US6555581B1 (en) | 2001-02-15 | 2003-04-29 | Jones Pharma, Inc. | Levothyroxine compositions and methods |
US20030224047A1 (en) * | 2001-02-15 | 2003-12-04 | Franz G. Andrew | Levothyroxine compositions and methods |
AU4061702A (en) * | 2001-05-15 | 2003-04-03 | Mcneil-Ppc, Inc. | Dip coating compositions containing starch or dextrin |
US20030070584A1 (en) * | 2001-05-15 | 2003-04-17 | Cynthia Gulian | Dip coating compositions containing cellulose ethers |
US20030072731A1 (en) * | 2001-05-15 | 2003-04-17 | Cynthia Gulian | Dip coating compositions containing starch or dextrin |
DE10125883A1 (de) | 2001-05-28 | 2002-12-12 | Serumwerk Bernburg Ag | Arzneimittel enthaltend einen Effektor des Glutathionmetabolismus zusammen mit alpha-Liponsäure im Rahmen der Nierenersatztherapie |
WO2002098403A1 (en) * | 2001-06-01 | 2002-12-12 | Georgetown University | Steroid hormone and non-steroidal anti-inflammatory drug combinations for inducing tumor cell apoptosis |
ITMI20011401A1 (it) * | 2001-07-02 | 2003-01-02 | Altergon Sa | Formulazioni farmaceutiche per ormoni tiroidei |
US20030198667A1 (en) * | 2001-08-10 | 2003-10-23 | Franz Andrew G. | Methods of producing dispersible pharmaceutical compositions |
US20030180353A1 (en) * | 2001-08-10 | 2003-09-25 | Franz G. Andrew | Stabilized pharmaceutical compositions |
US20030190349A1 (en) * | 2001-08-10 | 2003-10-09 | Franz G. Andrew | Methods of stabilizing pharmaceutical compositions |
US20030198671A1 (en) * | 2001-08-10 | 2003-10-23 | Franz G. Andrew | Levothyroxine compositions having unique plasma AUC properties |
US20030199586A1 (en) * | 2001-08-14 | 2003-10-23 | Franz G. Andrew | Unique levothyroxine aqueous materials |
US20030203967A1 (en) * | 2001-08-14 | 2003-10-30 | Franz G. Andrew | Levothyroxine compositions having unique Tmax properties |
US20030198672A1 (en) * | 2001-08-14 | 2003-10-23 | Franz G. Andrew | Levothyroxine compositions having unique triidothyronine plasma AUC properties |
US20030199587A1 (en) * | 2001-08-14 | 2003-10-23 | Franz G. Andrew | Levothyroxine compositions having unique Cmax properties |
US20030195253A1 (en) * | 2001-08-14 | 2003-10-16 | Franz G. Andrew | Unadsorbed levothyroxine pharmaceutical compositions, methods of making and methods of administration |
US20040146559A1 (en) * | 2002-09-28 | 2004-07-29 | Sowden Harry S. | Dosage forms having an inner core and outer shell with different shapes |
US8309118B2 (en) * | 2001-09-28 | 2012-11-13 | Mcneil-Ppc, Inc. | Film forming compositions containing sucralose |
US20040253312A1 (en) | 2001-09-28 | 2004-12-16 | Sowden Harry S. | Immediate release dosage form comprising shell having openings therein |
US20040043066A1 (en) * | 2001-10-29 | 2004-03-04 | Franz G. Andrew | Levothyroxine compositions having unique triiodothyronine Tmax properties |
US20030166732A1 (en) * | 2002-02-27 | 2003-09-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Ambroxol for the treatment of painful conditions in the mouth and pharyngeal cavity |
US7169450B2 (en) | 2002-05-15 | 2007-01-30 | Mcneil-Ppc, Inc. | Enrobed core |
US6946156B2 (en) * | 2002-05-15 | 2005-09-20 | Mcneil-Ppc, Inc. | Process for enrobing a core |
US7429619B2 (en) * | 2002-08-02 | 2008-09-30 | Mcneil Consumer Healthcare | Polyacrylic film forming compositions |
EP1396263A1 (en) * | 2002-08-09 | 2004-03-10 | Warner-Lambert Company | Film coating for tablets and caplets |
EP2255795A1 (en) | 2002-09-28 | 2010-12-01 | McNeil-PPC, Inc. | Immediate release dosage form comprising shell having openings therein |
US20050079213A1 (en) * | 2003-06-06 | 2005-04-14 | Unilab Pharmatech Ltd | Pharmaceutical compositions |
WO2005011707A1 (en) * | 2003-07-25 | 2005-02-10 | Warner Chilcott Company, Inc. | A doxycycline metal complex in a solid dosage form |
US7513091B2 (en) * | 2003-07-30 | 2009-04-07 | Merrion Research Iii Limited | Process and machine for automated manufacture of gastro-retentive devices |
US7879354B2 (en) | 2004-01-13 | 2011-02-01 | Mcneil-Ppc, Inc. | Rapidly disintegrating gelatinous coated tablets |
US8067029B2 (en) * | 2004-01-13 | 2011-11-29 | Mcneil-Ppc, Inc. | Rapidly disintegrating gelatinous coated tablets |
US20050202079A1 (en) * | 2004-03-15 | 2005-09-15 | Mylan Pharmaceuticals Inc. | Novel orally administrable formulation of nitrofurantoin and a method for preparing said formulation |
US20080102116A1 (en) * | 2004-09-13 | 2008-05-01 | Perrigo Company | Quick Dissolve Medicament and Method of Manufacturing |
CN101128206A (zh) * | 2005-01-21 | 2008-02-20 | 沃纳奇尔科特公司 | 固体剂型形式的四环素类金属络合物 |
US20060222699A1 (en) * | 2005-03-29 | 2006-10-05 | Jonathan Gilinski | Flavored vegetarian cellulose capsule and methods for producing said capsule. |
US20070072910A1 (en) * | 2005-09-29 | 2007-03-29 | Smith Michael L | Compositions and methods for lowering plasma concentrations of low density lipoproteins in humans |
CA2647536C (en) * | 2006-03-28 | 2015-01-27 | Mcneil-Ppc, Inc. | Non-homogenous dosage form coatings |
US20100086591A1 (en) | 2006-09-15 | 2010-04-08 | Murachanian Dennis C | Rapidly Disintegrating Dosage Form |
US20100029788A1 (en) * | 2006-09-29 | 2010-02-04 | John Pelesko | Wet edible pearlescent film coatings |
WO2008076902A1 (en) * | 2006-12-14 | 2008-06-26 | Sensient Colors Inc. | Pearlescent pigment compositions and methods for making and using the same |
MX2009013384A (es) * | 2007-06-08 | 2010-01-25 | Addrenex Pharmaceuticals Inc | Formulacion de liberacion extendida, y metodo para tratar disregulacion adrenergica. |
US20100172991A1 (en) * | 2007-06-08 | 2010-07-08 | Henry Joseph Horacek | Extended Release Formulation and Methods of Treating Adrenergic Dysregulation |
US20100092548A1 (en) * | 2008-08-28 | 2010-04-15 | Viva Pharmaceuticals Inc. | Chewable softgel capsules |
JP2012510511A (ja) * | 2008-12-01 | 2012-05-10 | インヴアスク セラピューテイックス インコーポレイテッド | レニン−アンジオテンシン−アルドステロン系阻害剤及びリポ酸化合物を含有する組成物、並びに、レニン−アンジオテンシン−アルドステロン系に関連した疾患の治療のためのそれらの使用 |
WO2012024360A2 (en) | 2010-08-18 | 2012-02-23 | Mcneil-Ppc, Inc. | Tablet sleeve for improved performance |
US9119793B1 (en) | 2011-06-28 | 2015-09-01 | Medicis Pharmaceutical Corporation | Gastroretentive dosage forms for doxycycline |
CN102688212B (zh) * | 2012-05-29 | 2013-08-07 | 北京均大高科科技孵化器有限公司 | 一种单硝酸异山梨酯缓释片及其制备方法 |
US20140141075A1 (en) | 2012-11-21 | 2014-05-22 | Warner Chilcott Company, Llc | 5-aminosalicylic acid capsule formulation |
US10842802B2 (en) | 2013-03-15 | 2020-11-24 | Medicis Pharmaceutical Corporation | Controlled release pharmaceutical dosage forms |
CN103461335B (zh) * | 2013-09-26 | 2015-08-05 | 卞佳林 | 一种多杀菌素和灰黄霉素复合微囊杀虫剂的制备方法 |
CN103461336B (zh) * | 2013-09-26 | 2015-08-05 | 卞佳林 | 一种多杀菌素和灰黄霉素复合微囊杀虫剂 |
EP3167870B1 (en) | 2015-11-16 | 2024-01-03 | Capsugel Belgium NV | Tamperproof oral dosage form |
EP3167869A1 (en) | 2015-11-16 | 2017-05-17 | Capsugel Belgium NV | Tamperproof oral dosage form |
EP3485911A4 (en) | 2016-07-06 | 2020-02-19 | Qualicaps Co., Ltd. | HARD CAPSULE WITH IMPROVED HARDNESS AND MANUFACTURING METHOD THEREOF |
RU2749902C2 (ru) * | 2018-10-31 | 2021-06-18 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Фармацевтическая композиция для лечения инфекционно-воспалительных заболеваний |
CN110279890A (zh) * | 2019-04-15 | 2019-09-27 | 首都医科大学附属北京世纪坛医院 | 基于脂质体的地塞米松/米诺环素在peek表面的修饰方法及应用 |
EP3805577A1 (en) * | 2019-10-11 | 2021-04-14 | Hilti Aktiengesellschaft | Threadlike package |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3258115A (en) * | 1965-05-12 | 1966-06-28 | Scherer Corp R P | Two-piece hard gelatin capsule |
GB1496737A (en) * | 1974-06-12 | 1977-12-30 | Scherer Corp R P | Capsule especially for medicaments |
US4466844A (en) * | 1983-09-19 | 1984-08-21 | Cosden Technology, Inc. | Gripper for capsule welder |
EP0225565A2 (de) * | 1985-12-06 | 1987-06-16 | Boehringer Ingelheim Kg | Teilbare Kapsel |
EP0435726A2 (en) * | 1989-12-29 | 1991-07-03 | Bristol-Myers Squibb Company | Capsule and caplet combination |
Family Cites Families (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US599865A (en) * | 1898-03-01 | Emanuel l | ||
US724436A (en) * | 1902-07-15 | 1903-04-07 | Ernest C Clark | Pill-coating machine. |
US1520940A (en) * | 1922-03-01 | 1924-12-30 | Dulitz August Adolf | Process for the manufacture of sealing caps and for applying them onto the vessels to be sealed |
US1685392A (en) * | 1925-08-12 | 1928-09-25 | Cellacote Company Inc | Preservative package and process of making the same |
US1657982A (en) * | 1926-02-15 | 1928-01-31 | Parke Davis & Co | Process of manufacturing gelatin capsules for use as bottle caps |
US1774258A (en) * | 1929-07-08 | 1930-08-26 | Raymond A English | Duplex capsule or the like |
US1872190A (en) * | 1930-06-07 | 1932-08-16 | Sindl Otto | Capsuling machine |
US1931765A (en) * | 1932-05-09 | 1933-10-24 | Basil E Leever | Beverage capsule |
US2663130A (en) * | 1946-12-26 | 1953-12-22 | American Cyanamid Co | Apparatus for producing symmetrical generally ellipsoidal capsules |
US3045641A (en) * | 1959-04-13 | 1962-07-24 | Pfizer & Co C | Apparatus for color-coding tablets |
US3228789A (en) * | 1962-10-22 | 1966-01-11 | Jacob A Glassman | Peroral capsules and tablets and the method for making same |
US3185626A (en) * | 1963-03-06 | 1965-05-25 | Sterling Drug Inc | Tablet coating method |
DE2010987C3 (de) * | 1970-03-09 | 1979-03-15 | Ibm Deutschland Gmbh, 7000 Stuttgart | Verfahren zum "Herstellen von Dunnschicht-Magnetköpfen mit magnetischer Anisotropie |
US3886940A (en) * | 1970-07-10 | 1975-06-03 | Squibb & Sons Inc | Capsule |
US3896762A (en) * | 1973-12-07 | 1975-07-29 | Purdue Research Foundation | Coating apparatus |
US3983258A (en) * | 1975-02-07 | 1976-09-28 | Continental Can Company, Inc. | Process of packaging edible products containing exposed bones |
US4562024A (en) * | 1982-07-06 | 1985-12-31 | Sterling Drug Inc. | Process for preparing granulate containing poorly compressible medicinally active matter |
JPS59131355A (ja) * | 1983-01-17 | 1984-07-28 | 森下仁丹株式会社 | 多重軟カプセルの製法 |
US4851230A (en) * | 1983-04-07 | 1989-07-25 | Bristol-Myers Company | Capsule shaped tablets |
US4591500A (en) * | 1983-04-25 | 1986-05-27 | Microencapsulation S.A. | Tablet having the shape of a capsule, process and device for its preparation |
US4684516A (en) * | 1983-08-01 | 1987-08-04 | Alra Laboratories, Inc. | Sustained release tablets and method of making same |
AU3188884A (en) * | 1983-08-26 | 1985-03-07 | Cosden Technology Inc. | Forming tamper-resistant tamper-indicative capsules |
US4928840A (en) * | 1986-02-25 | 1990-05-29 | American Home Products Corporation | Tamper proof encapsulated medicaments |
DE3684927D1 (de) * | 1986-10-20 | 1992-05-21 | Paolo Maso | Banderoliermachine fuer kapseln, gefuellt mit medikamenten. |
US5074426A (en) * | 1986-11-13 | 1991-12-24 | Warner-Lambert Company | Dividable capsule |
US4921108A (en) * | 1987-02-20 | 1990-05-01 | Mcneilab, Inc. | Apparatus for gelatin coating caplets |
US4820524A (en) * | 1987-02-20 | 1989-04-11 | Mcneilab, Inc. | Gelatin coated caplets and process for making same |
US4990358A (en) * | 1987-02-20 | 1991-02-05 | Mcneilab, Inc. | Method for double dipping gelatin coated caplets |
US4867983A (en) * | 1987-02-20 | 1989-09-19 | Mcneilab, Inc. | Method for double dipping gelating coated caplets |
US4966771A (en) * | 1987-02-20 | 1990-10-30 | Mcneilab, Inc. | Gelatin coated caplets and process for making same |
US4973480A (en) * | 1987-03-25 | 1990-11-27 | K.V. Pharmaceutical Co. | Tamper evident pharmaceutical capsule |
US4844906A (en) * | 1987-03-25 | 1989-07-04 | Kv Pharmaceutical Company | Tamper evident pharmaceutical capsule |
US4936074A (en) * | 1988-11-17 | 1990-06-26 | D. M. Graham Laboratories, Inc. | Process for preparing solid encapsulated medicament |
US4965089A (en) * | 1989-04-10 | 1990-10-23 | Sauter Manufacturing Corp. | Method and apparatus for the gelatin coating of caplets |
US5146730A (en) * | 1989-09-20 | 1992-09-15 | Banner Gelatin Products Corp. | Film-enrobed unitary-core medicament and the like |
US5456919A (en) * | 1989-12-29 | 1995-10-10 | Bristol-Myers Squibb Company | Capsule and caplet combination |
US5198227A (en) * | 1990-01-22 | 1993-03-30 | Mcneil-Ppc, Inc. | Dual subcoated simulated capsule medicament |
US5081822A (en) * | 1990-02-01 | 1992-01-21 | Warner-Lambert Company | Automatic caplet filler |
US5089270A (en) * | 1990-05-15 | 1992-02-18 | L. Perrigo Company | Capsule-shaped tablet |
US5213738A (en) * | 1990-05-15 | 1993-05-25 | L. Perrigo Company | Method for making a capsule-shaped tablet |
US5460824A (en) * | 1990-06-27 | 1995-10-24 | Warner-Lambert Company | Method for the preparation of an encapsulated medicament |
US5188688A (en) * | 1990-07-20 | 1993-02-23 | Minnesota Mining And Manufacturing Company | Method of sealing a gelatin capsule |
US5098715A (en) * | 1990-12-20 | 1992-03-24 | Burroughs Wellcome Co. | Flavored film-coated tablet |
US5114720A (en) * | 1990-12-27 | 1992-05-19 | American Cyanamid Company | Gelatin coated tablets and method for producing same |
US5317849A (en) * | 1992-08-07 | 1994-06-07 | Sauter Manufacturing Corporation | Encapsulation equipment and method |
US5415868A (en) * | 1993-06-09 | 1995-05-16 | L. Perrigo Company | Caplets with gelatin cover and process for making same |
JP3670016B2 (ja) * | 1994-12-16 | 2005-07-13 | ワーナー−ランバート・カンパニー | カプレットをカプセル内に封入する方法及びかかる方法により得ることができる固体剤形 |
GB0423515D0 (en) * | 2004-10-22 | 2004-11-24 | Phoenix Product Dev Ltd | A container |
-
1995
- 1995-11-09 JP JP51881996A patent/JP3670016B2/ja not_active Expired - Fee Related
- 1995-11-09 ES ES95939890T patent/ES2150017T3/es not_active Expired - Lifetime
- 1995-11-09 CN CN95196811A patent/CN1132566C/zh not_active Expired - Lifetime
- 1995-11-09 AT AT95939890T patent/ATE194486T1/de active
- 1995-11-09 MX MX9703773A patent/MX9703773A/es unknown
- 1995-11-09 CA CA002205553A patent/CA2205553C/en not_active Expired - Lifetime
- 1995-11-09 EP EP95939890A patent/EP0797424B1/en not_active Expired - Lifetime
- 1995-11-09 DK DK95939890T patent/DK0797424T3/da active
- 1995-11-09 DE DE69518006T patent/DE69518006T2/de not_active Expired - Lifetime
- 1995-11-09 PT PT95939890T patent/PT797424E/pt unknown
- 1995-11-09 KR KR1019970704011A patent/KR100468335B1/ko not_active IP Right Cessation
- 1995-11-09 WO PCT/US1995/014651 patent/WO1996018370A1/en active IP Right Grant
-
1996
- 1996-01-11 US US08/585,549 patent/US6080426A/en not_active Expired - Lifetime
-
2000
- 2000-09-26 GR GR20000402180T patent/GR3034491T3/el unknown
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3258115A (en) * | 1965-05-12 | 1966-06-28 | Scherer Corp R P | Two-piece hard gelatin capsule |
GB1496737A (en) * | 1974-06-12 | 1977-12-30 | Scherer Corp R P | Capsule especially for medicaments |
US4466844A (en) * | 1983-09-19 | 1984-08-21 | Cosden Technology, Inc. | Gripper for capsule welder |
EP0225565A2 (de) * | 1985-12-06 | 1987-06-16 | Boehringer Ingelheim Kg | Teilbare Kapsel |
EP0435726A2 (en) * | 1989-12-29 | 1991-07-03 | Bristol-Myers Squibb Company | Capsule and caplet combination |
Also Published As
Publication number | Publication date |
---|---|
KR980700050A (ko) | 1998-03-30 |
JP3670016B2 (ja) | 2005-07-13 |
PT797424E (pt) | 2000-10-31 |
ES2150017T3 (es) | 2000-11-16 |
ATE194486T1 (de) | 2000-07-15 |
US6080426A (en) | 2000-06-27 |
DE69518006T2 (de) | 2000-12-21 |
KR100468335B1 (ko) | 2005-09-02 |
MX9703773A (es) | 1997-08-30 |
DK0797424T3 (da) | 2000-10-23 |
CA2205553C (en) | 2009-04-07 |
WO1996018370A1 (en) | 1996-06-20 |
JPH11500326A (ja) | 1999-01-12 |
DE69518006D1 (de) | 2000-08-17 |
CA2205553A1 (en) | 1996-06-20 |
GR3034491T3 (en) | 2000-12-29 |
EP0797424A1 (en) | 1997-10-01 |
CN1170346A (zh) | 1998-01-14 |
EP0797424B1 (en) | 2000-07-12 |
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