CN106038010A - Cardiovascular artery stent - Google Patents

Cardiovascular artery stent Download PDF

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Publication number
CN106038010A
CN106038010A CN201610335723.6A CN201610335723A CN106038010A CN 106038010 A CN106038010 A CN 106038010A CN 201610335723 A CN201610335723 A CN 201610335723A CN 106038010 A CN106038010 A CN 106038010A
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China
Prior art keywords
parts
ring bodies
surplus
connection member
alloy material
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Application number
CN201610335723.6A
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Chinese (zh)
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CN106038010B (en
Inventor
孙三友
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Liu Xin
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Individual
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Priority to CN201610335723.6A priority Critical patent/CN106038010B/en
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Publication of CN106038010B publication Critical patent/CN106038010B/en
Expired - Fee Related legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02—Inorganic materials
    • A61L31/022—Metals or alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/082—Inorganic materials
    • A61L31/088—Other specific inorganic materials not covered by A61L31/084 or A61L31/086
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2420/00—Materials or methods for coatings medical devices
    • A61L2420/06—Coatings containing a mixture of two or more compounds

Abstract

The invention discloses a cardiovascular artery stent, which comprises a plurality of annular bodies and a plurality of connecting parts which are connected to the annular bodies, wherein the connecting parts and the annular bodies are coated with coatings; each annular body is provided with a plurality of triangular rib beams which are uniformly distributed along rings; the connecting parts are provided with V-shaped connecting rods; and spiral buckles, which are connected to the annular bodies, are arranged at the ends of the connecting rods. With the design of the V-shaped connecting rods, the cardiovascular artery stent has a certain flexibility, and by virtue of the buckles at the ends, the cardiovascular artery stent is more convenient to separate; by virtue of the triangular rib beams, the weight of the stent is relieved, and meanwhile, the intensity of the annular bodies is guaranteed; and with the application of the coating materials, the compatibility and corrosion resistance of the stent are improved, and meanwhile, the growth of scar tissues is inhibited.

Description

A kind of cardiovascular arterial bracket
Technical field
The present invention relates to a kind of cardiovascular arterial bracket, belongs to cardiovascular technical field.
Background technology
At present, coronary artery disease is modal disease in cardiovascular disease, be also mortality rate and sickness rate higher Disease, its main cause is the angiostenosis that atherosclerosis causes.Treatment coronary artery disease most common method is profit Angiostenosis is opened with sacculus, the most permanent placement metal supports, the most well-known support.But stent endoprosthesis The hyperplasia of rear inner membrance can cause the generation of restenosis, and the incidence rate of simple bare bracket restenosis is up to 10-30%, therefore crown Arterial bracket inserts the most important thing that postoperative restenosis is always in Coronary Artery Disease Intervention Treatment research, is wherein coated with intracoronary stent The research of layer is especially prominent.
Summary of the invention
A kind of cardiovascular arterial bracket, including multiple ring bodies and the plurality of connecting portion for connecting described ring bodies Part, connection member and ring bodies are coated with coating, and ring bodies has multiple along ring equally distributed triangle muscle beam, connection member Having V-arrangement connecting rod, connecting rod end has the screw-button for connecting ring bodies,
Connection member is copper-based alloy material, and it is elementary composition is (mass percent): Cr 12-13%, Sn 4-5%, Zn 2- 3%, Mo 0.5-0.6%, Mg 0.3-0.4%, Fe 0.1-0.2%, Ni0.08-0.09%, B 0.08-0.09%, Nd 0.05- 0.06%, Ga 0.04-0.05%, Ca0.02-0.03%, surplus is Cu,
Ring bodies is titanium-based alloy material, and it is elementary composition is (mass percent): Cr 7-8%, Si 4-5%, Zn 5-6%, B 1-2%, V 0.8-0.9%, Zr 0.7-0.8%, Bi 0.2-0.3%, Ag 0.2-0.3%, Mg0.1-0.2%, La 0.08- 0.09%, Y 0.04-0.05%, Nb0.06-0.07%, surplus is Ti,
Coating includes following mass fraction component: boron carbide 20-30 part, nickel oxide 10-20 part, six calcium boride 7-8 parts, aluminium oxide 1-2 part, niobium carbide 0. 7-0.8 part, molybdenum disilicide 0.5-0.6 part.
Described a kind of cardiovascular arterial bracket, connection member is copper-based alloy material, and it is elementary composition is (mass percent): Cr 12%, Sn 4%, Zn 2%, Mo 0.5%, Mg 0.3%, Fe 0.1%, Ni0.08%, B 0.08%, Nd 0.05%, Ga 0.04%, Ca0.02%, surplus is Cu.
Described a kind of cardiovascular arterial bracket, connection member is copper-based alloy material, and it is elementary composition is (percent mass Than): Cr 12.5%, Sn 4.5%, Zn 2.5%, Mo 0.55%, Mg 0.35%, Fe 0.15%, Ni0.085%, B 0.085%, Nd 0.055%, Ga 0.045%, Ca0.025%, surplus is Cu.
Described a kind of cardiovascular arterial bracket, connection member is copper-based alloy material, and it is elementary composition is (percent mass Than): Cr 13%, Sn 5%, Zn 3%, Mo 0.6%, Mg 0.4%, Fe 0.2%, Ni 0.09%, B 0.09%, Nd 0.06%, Ga 0.05%, Ca 0.03%, surplus is Cu.
Described a kind of cardiovascular arterial bracket, ring bodies is titanium-based alloy material, and it is elementary composition is (percent mass Than): Cr 7%, Si 4%, Zn 5%, B 1%, V 0.8%, Zr 0.7%, Bi 0.2%, Ag 0.2%, Mg0.1%, La 0.08%, Y 0.04%, Nb0.06%, surplus is Ti.
Described a kind of cardiovascular arterial bracket, ring bodies is titanium-based alloy material, and it is elementary composition is (percent mass Than): Cr 8%, Si 5%, Zn 6%, B 2%, V 0.9%, Zr 0.8%, Bi 0.3%, Ag 0.3%, Mg 0.2%, La 0.09%, Y 0.05%, Nb 0.07%, surplus is Ti.
Described a kind of cardiovascular arterial bracket, ring bodies is titanium-based alloy material, and it is elementary composition is (percent mass Than): Cr 7.5%, Si 4.5%, Zn 5.5%, B 1.5%, V 0.85%, Zr 0.75%, Bi 0.25%, Ag 0.25%, Mg0.15%, La 0.085%, Y 0.045%, Nb0.065%, surplus is Ti.
Described a kind of cardiovascular arterial bracket, coating includes: boron carbide 20 parts, nickel oxide 10 parts, six calcium borides 7 parts, Aluminium oxide 1 part, niobium carbide 0.7 part, molybdenum disilicide 0.5 part.
Described a kind of cardiovascular arterial bracket, coating includes: boron carbide 30 parts, nickel oxide 20 parts, six calcium borides 8 parts, Aluminium oxide 2 parts, niobium carbide 0.8 part, molybdenum disilicide 0.6 part.
Described a kind of cardiovascular arterial bracket, coating includes: boron carbide 25 parts, nickel oxide 15 parts, six calcium borides 7.5 Part, aluminium oxide 1.5 parts, niobium carbide 0.75 part, molybdenum disilicide 0.55 part.
State summary of the invention having the beneficial effects that relative to prior art: 1) ring bodies uses titanium alloy to ensure that its intensity Needing, connection member uses acid bronze alloy, and it has certain elastic stability ensureing shape with toughness；2) cardiovascular of the present invention Arterial bracket use connection member and ring bodies Split type structure ensure that the supportive of support in turn ensure that its suitable with blood vessel, and And length can also be adjusted the most easily；3) to ensure that cardiovascular arterial bracket has certain for the design of V-arrangement connecting rod Flexibility, the clasp of end makes to separate convenient；4) triangle muscle beam can both alleviate the quality of support and in turn ensure that ring The intensity of shape body, 5) coating material improves the compatibility corrosion resistance of support and suppresses scar tissue growth.
Accompanying drawing explanation
Fig. 1 is cardiovascular arterial bracket schematic diagram；
Fig. 2 is connection member schematic diagram；
Fig. 3 is ring bodies schematic diagram.
Detailed description of the invention
In order to the technical characteristic of the present invention, purpose and effect are more clearly understood from, now describe the present invention's in detail Detailed description of the invention.
A kind of cardiovascular arterial bracket as Figure 1-3, including multiple ring bodies 1 and the plurality of for connecting described ring The connection member 2 of shape body, ring bodies has multiple along ring equally distributed triangle muscle beam 3, and connection member has V-arrangement connecting rod 4, connecting rod end has the screw-button 5 for connecting ring bodies,
Connection member and ring bodies use casting method manufacture,
The component (accompanying drawing is not shown) making ring bodies be connected also is included with connecting rod end fastener on ring bodies,
Embodiment 1
A kind of cardiovascular arterial bracket, including multiple ring bodies and the plurality of connection member for connecting described ring bodies, Connection member and ring bodies are coated with coating, and ring bodies has multiple along ring equally distributed triangle muscle beam, and connection member has V-arrangement connecting rod, connecting rod end is had to have the screw-button for connecting ring bodies,
Connection member is copper-based alloy material, and it is elementary composition is (mass percent): Cr 12%, Sn 4%, Zn 2%, Mo 0.6%, Mg 0.4%, Fe 0.1%, Ni0.09%, B 0.08%, Nd 0.06%, Ga 0.04%, Ca0.03%, surplus is Cu,
Ring bodies is titanium-based alloy material, and it is elementary composition is (mass percent): Cr 7%, Si 4%, Zn 6%, B 2%, V 0.8%, Zr 0.7%, Bi 0.2%, Ag 0.3%, Mg0.2%, La 0.08%, Y 0.05%, Nb0.06%, surplus is Ti,
Coating includes: boron carbide 20 parts, nickel oxide 10 parts, six calcium borides 8 parts, aluminium oxide 2 parts, niobium carbide 0.7 part, molybdenum disilicide 0.5 part.
Embodiment 2
A kind of cardiovascular arterial bracket, including multiple ring bodies and the plurality of connection member for connecting described ring bodies, Connection member and ring bodies are coated with coating, and ring bodies has multiple along ring equally distributed triangle muscle beam, and connection member has V-arrangement connecting rod, connecting rod end is had to have the screw-button for connecting ring bodies,
Connection member is copper-based alloy material, and it is elementary composition is (mass percent): Cr 13%, Sn 5%, Zn 3%, Mo 0.5%, Mg 0.4%, Fe 0.1%, Ni0.09%, B 0.09%, Nd 0.06%, Ga 0.05%, Ca0.02%, surplus is Cu,
Ring bodies is titanium-based alloy material, and it is elementary composition is (mass percent): Cr 8%, Si 5%, Zn 6%, B 2%, V 0.9%, Zr 0.8%, Bi 0.2%, Ag 0.3%, Mg0.2%, La 0.09%, Y 0.05%, Nb0.06%, surplus is Ti,
Coating includes: boron carbide 20 parts, nickel oxide 20 parts, six calcium borides 7 parts, aluminium oxide 2 parts, niobium carbide 0.8 part, molybdenum disilicide 0.6 part.
Embodiment 3
A kind of cardiovascular arterial bracket, including multiple ring bodies and the plurality of connection member for connecting described ring bodies, Connection member and ring bodies are coated with coating, and ring bodies has multiple along ring equally distributed triangle muscle beam, and connection member has V-arrangement connecting rod, connecting rod end is had to have the screw-button for connecting ring bodies,
Connection member is copper-based alloy material, and it is elementary composition is (mass percent): Cr 12.5%, Sn 4.5%, Zn 2.5%, Mo 0.55%, Mg 0.35%, Fe 0.15%, Ni0.085%, B 0.085%, Nd 0.055%, Ga 0.045%, Ca0.025%, surplus is Cu,
Ring bodies is titanium-based alloy material, and it is elementary composition is (mass percent): Cr 7.5%, Si 4.5%, Zn 5.5%, B 1.5%, V 0.85%, Zr 0.75%, Bi 0.25%, Ag 0.25%, Mg0.15%, La 0.085%, Y 0.045%, Nb0.065%, surplus is Ti,
Coating includes: boron carbide 25 parts, nickel oxide 15 parts, six calcium borides 7.5 parts, aluminium oxide 1.5 parts, niobium carbide 0.75 part, two Molybdenum silicide 0.55 part.
Embodiment 4
A kind of cardiovascular arterial bracket, including multiple ring bodies and the plurality of connection member for connecting described ring bodies, Connection member and ring bodies are coated with coating, and ring bodies has multiple along ring equally distributed triangle muscle beam, and connection member has V-arrangement connecting rod, connecting rod end is had to have the screw-button for connecting ring bodies,
Connection member is copper-based alloy material, and it is elementary composition is (mass percent): Cr 12.4%, Sn 4.3%, Zn 2.2%, Mo 0.57%, Mg 0.36%, Fe 0.18%, Ni0.089%, B 0.088%, Nd 0.057%, Ga 0.046%, Ca0.029%, surplus is Cu,
Ring bodies is titanium-based alloy material, and it is elementary composition is (mass percent): Cr 7.7%, Si 4.4%, Zn 5.3%, B 1.4%, V 0.88%, Zr 0.77%, Bi 0.24%, Ag 0.23%, Mg0.12%, La 0.082%, Y 0.041%, Nb0.063%, surplus is Ti,
Coating includes: boron carbide 28 parts, nickel oxide 14 parts, six calcium borides 7.8 parts, aluminium oxide 1.3 parts, niobium carbide 0.73 part, two Molybdenum silicide 0.53 part.
Embodiment 5
A kind of cardiovascular arterial bracket, including multiple ring bodies and the plurality of connection member for connecting described ring bodies, Connection member and ring bodies are coated with coating, and ring bodies has multiple along ring equally distributed triangle muscle beam, and connection member has V-arrangement connecting rod, connecting rod end is had to have the screw-button for connecting ring bodies,
Connection member is copper-based alloy material, and it is elementary composition is (mass percent): Cr 12.9%, Sn 4.8%, Zn 2.6%, Mo 0.54%, Mg 0.38%, Fe 0.18%, Ni0.089%, B 0.087%, Nd 0.056%, Ga 0.047%, Ca0.029%, surplus is Cu,
Ring bodies is titanium-based alloy material, and it is elementary composition is (mass percent): Cr 7.8%, Si 4.4%, Zn 5.3%, B 1.9%, V 0.87%, Zr 0.76%, Bi 0.27%, Ag 0.23%, Mg0.18%, La 0.087%, Y 0.048%, Nb0.067%, surplus is Ti,
Coating includes: boron carbide 23 parts, nickel oxide 18 parts, six calcium borides 7.8 parts, aluminium oxide 1.4 parts, niobium carbide 0.78 part, two Molybdenum silicide 0.53 part.

Claims (10)

1. a cardiovascular arterial bracket, including multiple ring bodies and the plurality of connecting portion for connecting described ring bodies Part, connection member and ring bodies are coated with coating, and ring bodies has multiple along ring equally distributed triangle muscle beam, connection member Having V-arrangement connecting rod, connecting rod end has the screw-button for connecting ring bodies,
Connection member is copper-based alloy material, and it is elementary composition is (mass percent): Cr 12-13%, Sn 4-5%, Zn 2- 3%, Mo 0.5-0.6%, Mg 0.3-0.4%, Fe 0.1-0.2%, Ni0.08-0.09%, B 0.08-0.09%, Nd 0.05- 0.06%, Ga 0.04-0.05%, Ca0.02-0.03%, surplus is Cu,
Ring bodies is titanium-based alloy material, and it is elementary composition is (mass percent): Cr 7-8%, Si 4-5%, Zn 5-6%, B 1-2%, V 0.8-0.9%, Zr 0.7-0.8%, Bi 0.2-0.3%, Ag 0.2-0.3%, Mg0.1-0.2%, La 0.08- 0.09%, Y 0.04-0.05%, Nb0.06-0.07%, surplus is Ti,
Coating includes following mass fraction component: boron carbide 20-30 part, nickel oxide 10-20 part, six calcium boride 7-8 parts, aluminium oxide 1-2 part, niobium carbide 0. 7-0.8 part, molybdenum disilicide 0.5-0.6 part.
2. a kind of cardiovascular arterial bracket as claimed in claim 1, connection member is copper-based alloy material, and it is elementary composition For (mass percent): Cr 12%, Sn 4%, Zn 2%, Mo 0.5%, Mg 0.3%, Fe 0.1%, Ni0.08%, B 0.08%, Nd 0.05%, Ga 0.04%, Ca0.02%, surplus is Cu.
3. a kind of cardiovascular arterial bracket as claimed in claim 1, connection member is copper-based alloy material, and it is elementary composition For (mass percent): Cr 12.5%, Sn 4.5%, Zn 2.5%, Mo 0.55%, Mg 0.35%, Fe 0.15%, Ni0.085%, B 0.085%, Nd 0.055%, Ga 0.045%, Ca0.025%, surplus is Cu.
4. a kind of cardiovascular arterial bracket as claimed in claim 1, connection member is copper-based alloy material, and it is elementary composition For (mass percent): Cr 13%, Sn 5%, Zn 3%, Mo 0.6%, Mg 0.4%, Fe 0.2%, Ni 0.09%, B 0.09%, Nd 0.06%, Ga 0.05%, Ca 0.03%, surplus is Cu.
5. cardiovascular arterial bracket as claimed in claim 1 a kind of, ring bodies is titanium-based alloy material, and it is elementary composition is (mass percent): Cr 7%, Si 4%, Zn 5%, B 1%, V 0.8%, Zr 0.7%, Bi 0.2%, Ag 0.2%, Mg0.1%, La 0.08%, Y 0.04%, Nb0.06%, surplus is Ti.
6. cardiovascular arterial bracket as claimed in claim 1 a kind of, ring bodies is titanium-based alloy material, and it is elementary composition is (mass percent): Cr 8%, Si 5%, Zn 6%, B 2%, V 0.9%, Zr 0.8%, Bi 0.3%, Ag 0.3%, Mg 0.2%, La 0.09%, Y 0.05%, Nb 0.07%, surplus is Ti.
7. cardiovascular arterial bracket as claimed in claim 1 a kind of, ring bodies is titanium-based alloy material, and it is elementary composition is (mass percent): Cr 7.5%, Si 4.5%, Zn 5.5%, B 1.5%, V 0.85%, Zr 0.75%, Bi 0.25%, Ag 0.25%, Mg0.15%, La 0.085%, Y 0.045%, Nb0.065%, surplus is Ti.
8. a kind of cardiovascular arterial bracket as claimed in claim 1, coating includes: boron carbide 20 parts, nickel oxide 10 parts, six boron Change calcium 7 parts, aluminium oxide 1 part, niobium carbide 0.7 part, molybdenum disilicide 0.5 part.
9. a kind of cardiovascular arterial bracket as claimed in claim 9, coating includes: boron carbide 20 parts, nickel oxide 10 parts, six boron Change calcium 7 parts, aluminium oxide 1 part, niobium carbide 0.7 part, molybdenum disilicide 0.5 part.
10. a kind of cardiovascular arterial bracket as claimed in claim 1, coating includes: boron carbide 25 parts, nickel oxide 15 parts, six Calcium boride 7.5 parts, aluminium oxide 1.5 parts, niobium carbide 0.75 part, molybdenum disilicide 0.55 part.
CN201610335723.6A 2016-05-19 2016-05-19 A kind of cardiovascular arterial bracket Expired - Fee Related CN106038010B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108670510A (en) * 2018-05-22 2018-10-19 淮阴工学院 A kind of intracranial vessel holder that compliance is excellent

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060265048A1 (en) * 2005-05-18 2006-11-23 Advanced Cardiovascular Systems, Inc. Polymeric stent patterns
CN101448534A (en) * 2006-05-17 2009-06-03 生物技术公司 Anisotropic nanoporous coatings for medical implants
CN201840555U (en) * 2010-03-10 2011-05-25 谢建 Vessel stent being beneficial to being pressed and held
CN104127268A (en) * 2014-06-16 2014-11-05 苏州固基电子科技有限公司 Vascular stent firm in supporting

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060265048A1 (en) * 2005-05-18 2006-11-23 Advanced Cardiovascular Systems, Inc. Polymeric stent patterns
CN101448534A (en) * 2006-05-17 2009-06-03 生物技术公司 Anisotropic nanoporous coatings for medical implants
CN201840555U (en) * 2010-03-10 2011-05-25 谢建 Vessel stent being beneficial to being pressed and held
CN104127268A (en) * 2014-06-16 2014-11-05 苏州固基电子科技有限公司 Vascular stent firm in supporting

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108670510A (en) * 2018-05-22 2018-10-19 淮阴工学院 A kind of intracranial vessel holder that compliance is excellent
CN108670510B (en) * 2018-05-22 2020-03-27 淮阴工学院 Intracranial vascular stent with excellent flexibility

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