CN105726119A - Liquid metal bath pool type electrode electrotherapy device - Google Patents

Liquid metal bath pool type electrode electrotherapy device Download PDF

Info

Publication number
CN105726119A
CN105726119A CN201610053372.XA CN201610053372A CN105726119A CN 105726119 A CN105726119 A CN 105726119A CN 201610053372 A CN201610053372 A CN 201610053372A CN 105726119 A CN105726119 A CN 105726119A
Authority
CN
China
Prior art keywords
liquid metal
metal bath
bath pool
electrode
pool electrode
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610053372.XA
Other languages
Chinese (zh)
Inventor
孙旭阳
刘静
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tsinghua University
Original Assignee
Tsinghua University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tsinghua University filed Critical Tsinghua University
Priority to CN201610053372.XA priority Critical patent/CN105726119A/en
Publication of CN105726119A publication Critical patent/CN105726119A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation

Abstract

The invention belongs to medical equipment, and particularly relates to a liquid metal bath pool type electrode electrotherapy device. The device comprises a liquid metal bath pool type electrode, a plurality of metal probe guide rods, a data acquisition instrument, a controller and a computer. The electrode contains liquid metal which is used for making contact with the specific body surface of the human body. The metal probe guide rods are used for piercing into target tissue. The liquid metal bath pool type electrode and the metal probe guide rods are connected with an external high-frequency power source through wires respectively. The data acquisition instrument is used for monitoring temperature data in the body and electrode input parameters. The controller is used for controlling the current and voltage output of the electrode. The computer is used for receiving and displaying the data information of the data acquisition instrument, analyzing and processing the data, and generating a human body interior temperature image. The electrotherapy device is convenient to operate, the temperature is easy to control, focus conformal heating or electric stimulation can be achieved on the minimally invasive condition, and clinic requirements are well met.

Description

A kind of liquid metal bath pool electrode electrotherapeutic apparatus
Technical field
The invention belongs to armarium, be specifically related to a kind of liquid metal bath pool electrode electrotherapeutic apparatus.
Background technology
Tumor has become as the principal disease threatening present human health so far.The major way of traditional treatment tumor is surgical operation, but to be the shape of tumor good not adjacent with important organa parenchymatosum again for this operating applicable elements.But the size shape that practical situation is often tumor is irregular.This situation tends not to eradicate by surgical operation, and the probability that recurrence and transfer again occur is very big, causes secondary to operate on misery for patient.
Microwave is the means of the emerging treatment tumor grown up, ultimate principle is owing to normal cell is different to the tolerance of temperature from tumor cell, namely tumor cell is often thermo-labile, under hyperthermia treatment, just can reach to kill tumor cell, normal cell is not caused again the effect of damage simultaneously.Owing to it can heat tumor tissues targetedly, treatment extensively, without complication and side effect after treatment, even can the immunity of enhancing patient's body of significance, evident in efficacy thus have the good reputation of " green remedy ".Additionally, electrotherapy is also a kind of physical therapy modalities that human body side effect is less, just deepening continuously clinical practice.In many situations, for pathological tissues such as parkinson case, implement specific electricity irritation and contribute to improving the quality of life of patient.It practice, be simultaneous in thermotherapy and the many situations of electrotherapy.
A few quasi-representative methods of heating ablation are radio-frequency (RF) ablation, and microwave ablation, high intensity focused ultrasound melts.Radio-frequency (RF) ablation is, under the guiding of iconography, electrode is directly inserted into inside tumor, the molecule near electrode and ion generation high-speed motion is caused by high frequency electric, produce friction, utilize vibration heat production, make tumor tissues local generation high temperature kill the technology of tumor cell, be up to the present apply one of neoplastic fevers ablation techniques the most ripe.
But, the equipment that present neoplastic fevers melts is all complex, and is difficult to reach, with human body, the degree that well suits.
Summary of the invention
Present invention aims to defect and deficiency that prior art exists, it is provided that a kind of liquid metal bath pool electrode electrotherapeutic apparatus, it is possible to rapidly to destination organization quickly heating or electricity irritation selectively.
For achieving the above object, the present invention is by the following technical solutions:
A kind of liquid metal bath pool electrode electrotherapeutic apparatus, including:
Liquid metal bath pool electrode, described electrode is built with liquid metal, for contacting with the specific body surface of human body;
Some metal probe guide rods, are used for thrusting inside destination organization;Described liquid metal bath pool electrode is connected with external high frequency electric source respectively through wire with metal probe guide rod;
Data collecting instrument, for monitoring internal temperature data and liquid metal bath pool electrode input parameter;
Controller, for controlling electric current and the voltage output of liquid metal bath pool electrode;
Data, for receiving and the data message of video data harvester, are analyzed, process, and generate inside of human body temperature pattern by computer.
Further, also include auxiliary support apparatus, be used for fixing or support human synovial position.
Further, the liquid metal contained in described liquid metal bath pool electrode adopts liquid metal or the alloy material at ambient temperature with mobility, including gallium or indium or gallium-indium-tin alloy.
Further, described external high frequency electric source adopts high frequency electric generating means, power frequency 0.1Hz~2000MHz;Supply voltage is 0.1V~36V.
Further, described liquid metal bath pool electrode adopts a kind of material in rustless steel, glass, plastics or timber to prepare.
Further, described metal probe guide rod front end is tip shape;Metal probe guide rod radius is 0.5~5mm, and length is 1~10cm.
Further, the parcel woollen blanket for strengthening whole-body hyperthermia effect and the infrared radiometer that ligand external exposure heats up also are included.
Further, also including, in heating process, for protecting human body etc. from the cooling device adding hot injury, described cooling device includes: head cooling water bag, frozen water bag or semiconductor cooler.
Compared with prior art, the present invention has following useful technique effect: the present invention by immersing among the flexible electrode of liquid metal bath pool electrode by human body specific part, and another rigid electrode metal probe guide rod is thrust tumor or destination organization center, effect by the high-frequency electric field put on electrode, the Joule heat running through deep tissue is relied on, rapidly to quickly heating or the electricity irritation selectively of internal destination organization, to be achieved in the accurate treatment of destination organization or tumor.And the present invention passes through liquid metal bath pool electrode, realization fits tightly with body surface, by arranging metal probe guide rod, can according to adding heat and heating position needs, many metal probes can be inserted in the body of many places in a minimally invasive manner and lead to adjust position and the intensity of caloric value or electricity irritation, traumatic only small to patient;Thus providing a kind of input corresponding relation quickly regulating and controlling body surface and extrinsic current flexibly, it is achieved fluid electrode contact area can be changed for different parts and reach medical treatment purpose.High-frequency electric field produced by the present invention available electrode needle simultaneously, it is convenient to in-house temperature field, by means of electrical impedance tomography technology, is implemented reconstruct, and shown at computer terminal by ground.The invention provides the medical electrode technology of a kind of novel concept;Have easy and simple to handle, it may be achieved selectivity heating or electricity irritation, to features such as patient's invasive are little.
Accompanying drawing explanation
Fig. 1 is overall structure schematic diagram of the present invention.
Detailed description of the invention
Below in conjunction with accompanying drawing, the present invention is described in further detail.
Referring to Fig. 1, the present invention includes: including: liquid metal bath pool electrode 1, and described electrode is built with liquid metal, for contacting with the specific body surface of human body;Some metal probe guide rods 4, are used for thrusting inside destination organization;Described liquid metal bath pool electrode 1 is connected with external high frequency electric source 5 respectively through wire 2 with metal probe guide rod 4;Data collecting instrument 3, for monitoring internal temperature data and liquid metal bath pool electrode 1 inputs parameter;Controller 6, for controlling electric current and the voltage output of liquid metal bath pool electrode 1;Data, for receiving and the data message of video data harvester 3, are analyzed, process by computer 7, and generate inside of human body temperature display image.
Also include auxiliary support apparatus 8, be used for fixing or support human synovial position.Also include the parcel woollen blanket for strengthening whole-body hyperthermia effect and the infrared radiometer etc. that ligand external exposure heats up.Also include, in heating process, for protecting human body significant points such as brain etc. to cool down water bag, frozen water bag or semiconductor cooler etc. from the head adding hot injury.
Described external high frequency electric source 5 adopts high frequency electric generating means, power frequency 0.1Hz~2000MHz;Supply voltage is 0.1V~36V.The liquid metal contained in described liquid metal bath pool electrode 1 adopts fusing point to form at elemental metals or the alloy of the gallium indium tin etc. of near room temperature.
Wherein, liquid metal bathing pool container is made up of materials such as rustless steel, glass, plastics or even timber, bathing pool size specifically heats position and is divided into adaptation upper limb according to patient, the bathing pool such as lower limb or whole body, in pond liquid metal can by have under room temperature condition mobility gallium, indium, the elemental metals of stannum etc. or alloy form.The concrete shape of bathing pool can be cuboid, Elliptic Cylinder, cylinder etc..It is generally cuboid bathing pool.It is among metal bathing pool for quantitative liquid metal, liquid metal bathing pool can pass through to move up and down thus controlling the degree of depth that human body different parts infiltrate in liquid bathing pool and heating to implement specific aim, and bathing pool connects with wire, high frequency electric source etc., as therapy component.And contact everywhere with body surface over the course for the treatment of, and connect with wire, high frequency electric source etc., as therapy component.
Wire 2 is common current wire, can be twisted into by one or more strands of wires.
External high frequency electric source equipment 5 adopts high frequency electric generating means, directly can purchase or customized from market, and its power frequency can at 0.1Hz to 2000MHz, and provided supply voltage can for 0.1V to 36V, and wherein 36V is the maximum safe voltage that human body can bear.
Can implementing internal heating or electricity irritation due to accurate electrotherapeutic apparatus provided by the invention, thus produced tissue programming rate is very fast, the design of bathing pool formula is very convenient especially, thus substantially reduces treatment time and alleviates patient's misery.There is original advantage in clinical tumor.
The use procedure of this device is as follows:
1. clinician does conventional Preoperative Method, does sterilization of instruments, and operation region of interest is done local anesthesia.
2., according to the operation plan designed in advance, by the heated site boundary joint of human body such as wrist, elbow, ankle etc. fixes.Regulate the height of liquid metal bathing pool again, make heated position be immersed among bathing pool with best height.
3., according to the operation plan designed in advance, metal probe is thrust in tumor locus to be heated.
4. pair metal probe applies high frequency electric, and then, heating by organization internal corresponding between metal probe and the skin body surface immersed in liquid metal, body temperature raises.Heat in process, the body temperature of patient is monitored, inquire patients' feeling, carry out nursing
5. for preventing some key positions of human body thermally damaged, such as brain, while heating, also take local cooling's measure, as adopted ice cap or cooling water that brain is cooled down.
In a word, accurate electrotherapeutic apparatus provided by the invention, is the physical therapy modalities that deep destination organization can be made directly precisely heating or electricity irritation of a kind of invasive, it is contemplated that can play pivotal role in the clinical practice such as tumor, treatment of Parkinson disease.
Before the treatment, position to be heated for human body is infiltrated in liquid metal bathing pool electrode 1 by clinicist as required, and regulate height, metal probe guide rod can be used as the regulation and control sense of current and size to internal at CT or ultrasonic Conducted Puncture, clinician can be dependent on data collecting instrument collection and show information on the computer screen, the input current parameter of regulation and control metal electrode, reaches selectively in-vivo tissue to be heated up.
Over the course for the treatment of, liquid metal contacts with the specific body surface of human body, the metal probe guide rod 4 therapeutic scheme requirement according to operation, thrusts in tumor or destination organization, and connects with wire 2, high frequency electric source 5 etc., as therapy component;Data collecting instrument 3 is in order to monitor internal heated condition and electrode input parameter at any time, in order to adjust input current size in time, thus realizing selectivity heating.In the process, controller 6, as servo control mechanism, is dependent on the order execution action of data collecting instrument 3;Computer 7 then completes about the analysis of data, process, and Image texture coordinate the work of each parts, auxiliary support apparatus 8 then before the treatment starts, fixing human joint part.
In real process, according to adding heat and heating position needs, can insert many metal probe guide rods in the body of many places in a minimally invasive manner, including the contact surface adjusting human body and liquid metal bathing pool electrode, to adjust position and the intensity of caloric value or electricity irritation.Owing to this heating effect can produce at deep tissue after powered up, thus be the significantly high internal mode of heating of a kind of efficiency, have an advantage in that instrument is convenient directly, human body is directly immersed in, liquid metal has good compliance, there is better degree of laminating with human body, thus provide precisely heating and the electrical stimulus patterns of a kind of simple and fast.
It is worthy of note, owing to adopting the mode thrusting electrode, thus tissue resistance between metal electrode and liquid metal can be passed through and resist the relation between temperature, after measuring the electrical impedance organized between this, can the temperature of inside of human body be reconstructed out (in this respect by means of certain mathematical measure, forefathers have and utilize electrical impedance chromatographic technique to realize the trial that tissue temperature is measured, and directly use for reference).So, the present invention in fact provides a kind of method and apparatus that can simultaneously realize heating and temperature rebuilding.
It is also an advantage of the present invention that, traumatic only small to patient, heating rapidly, has invasive.Heating effect, then because the function of current is in deep tissue, adds heat and is adjusted as required in combinations with external bathing pool.This kind of clinical operation can be able to carry out at general out patient service, and this makes carrying out of the accurate heating ablation based on apparatus of the present invention or electrical stimulating therapy quite convenient.
The present invention's it is critical that has been firstly introduced the concept of liquid metal bathing pool electrode, utilizes liquid metal to have the good electric conductivity of the submissive performance of liquid and liquid metal, precisely melts or apparatus of electro-stimulation provides new method and thought for following.
It must be stressed that apparatus of the present invention are in actual use, applied voltage not can exceed that the tolerance limit of human-body safety.

Claims (8)

1. a liquid metal bath pool electrode electrotherapeutic apparatus, it is characterised in that including:
Liquid metal bath pool electrode (1), described electrode is built with liquid metal, for contacting with the specific body surface of human body;
Some metal probe guide rods (4), are used for thrusting inside destination organization;Described liquid metal bath pool electrode (1) is connected with external high frequency electric source (5) respectively through wire (2) with metal probe guide rod (4);
Data collecting instrument (3), for monitoring internal temperature data and liquid metal bath pool electrode (1) input parameter;
Controller (6), is used for controlling the electric current of liquid metal bath pool electrode (1) and voltage output;
Data, for receiving the data message with video data harvester (3), are analyzed, process, and generate inside of human body temperature pattern by computer (7).
2. a kind of liquid metal bath pool electrode electrotherapeutic apparatus according to claim 1, it is characterised in that also include auxiliary support apparatus (8), be used for fixing or support human synovial position.
3. a kind of liquid metal bath pool electrode electrotherapeutic apparatus according to claim 1, it is characterized in that, the liquid metal contained in described liquid metal bath pool electrode (1) adopts liquid metal or the alloy material at ambient temperature with mobility, including gallium or indium or gallium-indium-tin alloy.
4. a kind of liquid metal bath pool electrode electrotherapeutic apparatus according to claim 1, it is characterised in that described external high frequency electric source (5) adopts high frequency electric generating means, power frequency 0.1Hz~2000MHz;Supply voltage is 0.1V~36V.
5. a kind of liquid metal bath pool electrode electrotherapeutic apparatus according to claim 1, it is characterised in that described liquid metal bath pool electrode (1) adopts a kind of material in rustless steel, glass, plastics or timber to prepare.
6. a kind of liquid metal bath pool electrode electrotherapeutic apparatus according to claim 1, it is characterised in that described metal probe guide rod (4) front end is tip shape;Metal probe guide rod (4) radius is 0.5~5mm, and length is 1~10cm.
7. a kind of liquid metal bath pool electrode electrotherapeutic apparatus according to claim 1, it is characterised in that also include the parcel woollen blanket for strengthening whole-body hyperthermia effect and the infrared radiometer that ligand external exposure heats up.
8. a kind of liquid metal bath pool electrode electrotherapeutic apparatus according to claim 1; it is characterized in that, also include, in heating process; for protecting human body etc. from the cooling device adding hot injury, described cooling device includes: head cooling water bag, frozen water bag or semiconductor cooler.
CN201610053372.XA 2016-01-26 2016-01-26 Liquid metal bath pool type electrode electrotherapy device Pending CN105726119A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610053372.XA CN105726119A (en) 2016-01-26 2016-01-26 Liquid metal bath pool type electrode electrotherapy device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610053372.XA CN105726119A (en) 2016-01-26 2016-01-26 Liquid metal bath pool type electrode electrotherapy device

Publications (1)

Publication Number Publication Date
CN105726119A true CN105726119A (en) 2016-07-06

Family

ID=56246639

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610053372.XA Pending CN105726119A (en) 2016-01-26 2016-01-26 Liquid metal bath pool type electrode electrotherapy device

Country Status (1)

Country Link
CN (1) CN105726119A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106419895A (en) * 2016-11-14 2017-02-22 清华大学 Body surface electrode based on liquid metal and fast preparing method thereof
CN107684416A (en) * 2016-08-04 2018-02-13 云南科威液态金属谷研发有限公司 Glass-micropipe electrode based on liquid metal and preparation method thereof
CN107684420A (en) * 2016-08-04 2018-02-13 云南科威液态金属谷研发有限公司 A kind of liquid metal electrocardio electrode plate
CN108542743A (en) * 2018-05-04 2018-09-18 北京梦之墨科技有限公司 A kind of massage apparatus

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN87100574A (en) * 1986-01-29 1987-08-19 汉斯·奥洛夫·西奥多·威克塞尔 The method and apparatus of the fever therapy of tumor
CN1036703A (en) * 1989-01-14 1989-11-01 重庆地质仪器厂 Cancer therapeutic equipment is solidified in localized hyperthermia
US5540235A (en) * 1994-06-30 1996-07-30 Wilson; John R. Adaptor for neurophysiological monitoring with a personal computer
CN1220897A (en) * 1997-12-21 1999-06-30 祁任丽 New-type radio-frequency diathermy and device
CN2640513Y (en) * 2003-07-18 2004-09-15 威海市通联桑拿设备有限公司 Bathhouse pulse instrument
CN1953116A (en) * 2005-10-20 2007-04-25 安捷伦科技有限公司 Liquid metal switch employing a switching material containing gallium
CN1961987A (en) * 2005-11-08 2007-05-16 中国科学院理化技术研究所 Pole plate array heating device for general or local tumor thermotherapy
CN101856290A (en) * 2010-05-24 2010-10-13 清华大学 Wearable multi-field radiation whole-body hyperthermia device
CN102802346A (en) * 2011-05-27 2012-11-28 中国科学院理化技术研究所 Liquid-metal printed circuit board and preparation method thereof
CN103959029A (en) * 2011-09-24 2014-07-30 哈佛大学校长及研究员协会 Artificial skin and elastic strain sensor

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN87100574A (en) * 1986-01-29 1987-08-19 汉斯·奥洛夫·西奥多·威克塞尔 The method and apparatus of the fever therapy of tumor
CN1036703A (en) * 1989-01-14 1989-11-01 重庆地质仪器厂 Cancer therapeutic equipment is solidified in localized hyperthermia
US5540235A (en) * 1994-06-30 1996-07-30 Wilson; John R. Adaptor for neurophysiological monitoring with a personal computer
CN1220897A (en) * 1997-12-21 1999-06-30 祁任丽 New-type radio-frequency diathermy and device
CN2640513Y (en) * 2003-07-18 2004-09-15 威海市通联桑拿设备有限公司 Bathhouse pulse instrument
CN1953116A (en) * 2005-10-20 2007-04-25 安捷伦科技有限公司 Liquid metal switch employing a switching material containing gallium
CN1961987A (en) * 2005-11-08 2007-05-16 中国科学院理化技术研究所 Pole plate array heating device for general or local tumor thermotherapy
CN101856290A (en) * 2010-05-24 2010-10-13 清华大学 Wearable multi-field radiation whole-body hyperthermia device
CN102802346A (en) * 2011-05-27 2012-11-28 中国科学院理化技术研究所 Liquid-metal printed circuit board and preparation method thereof
CN103959029A (en) * 2011-09-24 2014-07-30 哈佛大学校长及研究员协会 Artificial skin and elastic strain sensor

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
(加)布朗诺维克等: "《电接触理论、应用与技术》", 31 October 2010, 机械工业出版社 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107684416A (en) * 2016-08-04 2018-02-13 云南科威液态金属谷研发有限公司 Glass-micropipe electrode based on liquid metal and preparation method thereof
CN107684420A (en) * 2016-08-04 2018-02-13 云南科威液态金属谷研发有限公司 A kind of liquid metal electrocardio electrode plate
CN106419895A (en) * 2016-11-14 2017-02-22 清华大学 Body surface electrode based on liquid metal and fast preparing method thereof
CN108542743A (en) * 2018-05-04 2018-09-18 北京梦之墨科技有限公司 A kind of massage apparatus

Similar Documents

Publication Publication Date Title
US11351401B2 (en) Band transducer ultrasound therapy
US20220096828A1 (en) Apparatus and method of non-invasive directional tissue treatment
EP3422965B1 (en) Device for eustachian tube modification
Pennes Analysis of tissue and arterial blood temperatures in the resting human forearm
Haemmerich et al. Hepatic bipolar radio-frequency ablation between separated multiprong electrodes
US8540705B2 (en) Devices and methods for percutaneous energy delivery
JP2013532513A (en) Multidisciplinary treatment system, method and apparatus for body controlling applications
US20100249772A1 (en) Treatment of skin deformation
IL259809B (en) Apparatus and cosmetic method for cosmetic treatment of human mucosal tissue
CN105726119A (en) Liquid metal bath pool type electrode electrotherapy device
US20220008112A1 (en) Ultrasound transducer and system for skin treatments
Samulski et al. Heating deep seated eccentrically located tumors with an annular phased array system: a comparative clinical study using two annular array operating configurations
Koch Radiofrequency nonablative tissue tightening
Duncan et al. Basic radiofrequency: physics and safety and application to aesthetic medicine
CN1961987A (en) Pole plate array heating device for general or local tumor thermotherapy
Kreindel et al. The basic science of radiofrequency-based devices
Antunes et al. Saline‐enhanced RF ablation on a cholangiocarcinoma: a numerical simulation
CN213940932U (en) Three-dimensional tumor thermal ablation instrument
Al_Dulamey The Development of microwave applications in medical field
EP3294405B1 (en) Apparatus of non-invasive directional tissue treatment using radiofrequency energy
Singh et al. Pre-clinical modeling and simulation of radiofrequency ablation in human lung tumor
Myoung et al. A design of RF stimulator which is similar to temperature distribution by moxibustion (preliminary study)
Hassan et al. A Review On Water Bolus Structure Integration For Non-Invasive Hyperthermia Treatment
Hu et al. Electrothermal analysis of radiofrequency tissue ablation with injectable flexible electrodes considering bio-heat transfer
Wang Comparative Analysis of Non-Invasive and Invasive Tumor Treatment Fields: A Simulation Study

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20160706

RJ01 Rejection of invention patent application after publication