CN105388276A - Blood reagent analysis system and analysis method - Google Patents
Blood reagent analysis system and analysis method Download PDFInfo
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- CN105388276A CN105388276A CN201610000339.0A CN201610000339A CN105388276A CN 105388276 A CN105388276 A CN 105388276A CN 201610000339 A CN201610000339 A CN 201610000339A CN 105388276 A CN105388276 A CN 105388276A
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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Abstract
A blood reagent analysis system and a blood reagent analysis system analysis method are used for measuring parameters of a blood sample, such as blood sugar content and cholesterol content. An error result of a redundant measuring channel is analyzed to give out a reliable measured value.
Description
Technical field
The present invention relates to a kind of bodily fluid analysis system, especially relate to a kind of blood analysis system and analytical approach.
Background technology
Body fluid refers to all types of fluent meterials comprising in human body or animal body and containing, and generally includes whole blood, lymph, urine, saliva, sweat etc., at clinicing aspect, relates generally to blood and the urine of human body.
At chemistry or clinicing aspect, analysis thing contained in blood sample to be carried out quantitatively or qualitative analysis is very important.Blood liquid is tested and can find out pathological state early and reliably and monitor condition targetedly and based on fact of case in clinical diagnosis. closing in the screening of blood is do a detection ahead of time to the hiding disease in everyone health, can carry out about the detection at function index for various composition, when any detection instruction is abnormal, namely represent that the health of individual has gone out certain some defect, prophylactic morbidity must be done sth. in advance and do a treatment in early days.
In blood analysis detects, the accuracy about measurement result is the major issue needing to consider.Especially for the detection of the glucose content determined in blood, because it is the basis that diabetic uses insulin dose, its measurement result needs the accuracy as far as possible ensureing measurement result.
In order to realize the reliability of measurement result, the patent of invention of 200810215254.X by arranging the assessment passage of redundancy in blood analysis system, when the measurement result deviation by this analytic system is greater than predetermined value, provide the information of this analytic system measurement result mistake, thus ensure that the accurate of measured value.But, redundancy is added due in wherein analytic system, as long as there is mistake in a Measurement channel in analytic system, even if another one Measurement channel is accurate, then measurement result also there will be deviation, this analytic system will provide the information of measurement result mistake, at this moment needs to re-start test.Namely the setting of this redundant channel adds the probability that system provides measurement result mistake, thus needs to retest, and increases the burden of patient.
Summary of the invention
The present invention, as the improvement of the patent of invention of 200810215254.X, can solve the problems referred to above of prior art, be quoted in full in this.
As one aspect of the present invention, provide a kind of Blood Kit analytical approach, comprise the steps: that (1) blood sample and reagent react at the first analysis area and the second analysis area; (2) simulating signal of the first analysis area and the second analysis area is generated by the first simulating signal measuring unit and the second simulating signal measuring unit; (3) the first digital signal and the second digital signal is generated by the first analog to digital converter and the second analog to digital converter respectively based on above-mentioned simulating signal; (4) the first digital signal and the second digital signal is stored by storer; (5) the first measured value and second measured value of blood sample is produced by the first assessment unit and the second assessment unit based on above-mentioned first digital signal and the second digital signal; (6) comparator unit compares the first measured value and the second measured value, judges whether its deviation is greater than specific threshold; (6.1) if this deviation is less than specific first threshold, analysis result generation unit uses any one in the first measured value and the second measured value as measurement result value, terminates this and measures; (6.2) if this deviation is greater than specific first threshold, step (7) is carried out; (7) comparator unit compares the first digital signal in storer and the second digital signal, judges whether the deviation of the first digital signal and the second digital signal is less than specific Second Threshold; (7.1) if this deviation is greater than specific Second Threshold, then analysis result generation unit provides the information of this measurement result mistake; (7.2) if this deviation is less than specific Second Threshold, step (8) is carried out; (8) by control module, the first digital signal is inputted the second assessment unit, the second digital signal inputs the first assessment unit; Described second assessment unit generates the 3rd measured value based on the first digital signal, and described first assessment unit generates the 4th measured value based on the second digital signal; (9) deviation S2 deviation S1, described second measured value and described four measured value between of comparator unit respectively between more described first measured value and described 4th measured value: if only there is S1 to be less than specific first threshold, then analysis result generation unit provides the measured value of described first measured value as this blood sample; If only there is S2 to be less than specific first threshold, then analysis result generation unit provides the measured value of described second measured value as this blood sample; Otherwise analysis result generation unit provides the information of this measurement result mistake.
As another aspect of the present invention, be provided for the analytic system of above-mentioned Blood Kit analytical approach, comprise: reagent system, first analysis area, second analysis area, the first simulating signal measuring unit, the second simulating signal measuring unit, first analog to digital converter, second analog to digital converter, the first assessment unit, the second assessment unit, storer, analysis result generation unit and control module.
Preferably, described first analysis area and the second analysis area, be respectively used to blood sample and react with reagent wherein; Described first simulating signal measuring unit and the second simulating signal measuring unit, the reaction respectively based on the first analysis area and the second analysis area produces analogue measurement signal; Described first analog to digital converter and the second analog to digital converter, carry out digitizing by the first simulating signal and the second simulating signal respectively, generates the first digital signal and the second digital signal; Described first assessment unit and the second assessment unit, its digital signal generated based on the first analog to digital converter and the second analog to digital converter respectively produces the first measured value and second measured value of blood sample; Comparator unit, its first measured value and second that can generate for the first assessment unit and the second assessment unit is measured and is compared: analysis result generation unit, and it generates the analysis result of single measurement; Storer, it can store the first digital signal and the second digital signal; Control module, it can control the input signal of the first assessment unit and the second assessment unit; Deviation between described comparator unit first measured value and the second measured value is greater than specific first threshold, whether described comparator unit can the first digital signal in more described storer and the second digital signal, based on the deviation of this multilevel iudge measurement result from the deviation of assessment unit; If the deviation of described first digital signal and the second digital signal is greater than specific Second Threshold, then judge that the deviation of measurement result is not from assessment unit, described analysis result generation unit provides the information of this measurement result mistake; If the deviation of described first digital signal and the second digital signal is less than Second Threshold, then judge that the deviation of measurement result is from assessment unit, according to described first digital signal, the second digital signal, the first measured value and the second measured value, described analysis result generation unit provides value that in described first measured value and the second measured value, measurement result the is correct measured value as this blood sample.
Accompanying drawing explanation
Fig. 1 is the schematic diagram of the Blood Kit analytic system of the embodiment of the present invention.
Fig. 2 is the process flow diagram of the blood analysis method of the embodiment of the present invention.
Embodiment
In order to be illustrated more clearly in the embodiment of the present invention or technical scheme of the prior art, be briefly described to the accompanying drawing used required in embodiment or description of the prior art below, apparently, accompanying drawing in the following describes is only some embodiments of the present invention, for those of ordinary skill in the art, under the prerequisite not paying creative work, other accompanying drawing can also be obtained according to these accompanying drawings.
The Blood Kit analytic system of the embodiment of the present invention, as shown in Figure 1, comprise reagent system (not shown), the first analysis area 1a and the second analysis area 1b, the first simulating signal measuring unit 2a and the second simulating signal measuring unit 2b, first analog to digital converter 3a and the second analog to digital converter 3b, first assessment unit 4a and the second assessment unit 4b, comparator unit 5, storer 6, control module 7, analysis result generation unit 8.
Reagent system is used for being used for and reaction of blood to the input of Blood Kit analytic system, the physical quantity of forming reactions blood parameters, after the measured value mensuration of this physical quantity, can pass through the model of this measured value and blood parameters, by the measured value of this physical quantity, determine blood parameters.Determined blood parameters can be as, blood-sugar content or cholesterol level.
First analysis area 1a and the second analysis area 1b is of similar shape and conversion zone, receives blood sample and the reagent of input identical type dosage wherein respectively, thus blood sample and reagent are reacted with reagent in each analysis area.The reaction occurred is the course of reaction that can provide blood parameters value, and such as can provide the reaction of optical change signal, also can be electrochemical reaction.
First simulating signal measuring unit 2a and the second simulating signal measuring unit 2b, the reaction respectively based on the first analysis area 1a and the second analysis area 1b produces analogue measurement signal.Wherein, measuring unit is the measuring sensor corresponding to analysis area reaction type, and such as, when what analysis area produced is the optical signalling of change, measuring unit can make such as optical strength measuring unit; When there is electrochemical reaction in analysis area, measuring unit can be as voltage or current sensor.
First analog to digital converter 3a and the second analog to digital converter 3b, the second simulating signal that its first simulating signal measured by the first simulating signal measuring unit 2a respectively and the first simulating signal measuring unit 2a measure carries out digitizing, generates the first digital signal and the second digital signal.
First assessment unit 4a and the second assessment unit 4b, it is respectively by respective model, based on the first measured value and second measured value of the first digital signal and the second digital signal determination blood sample.Storer 6, it can store the first digital signal and the second digital signal.Control module 7, it can read the first digital signal in storer 6 and the second digital signal, and can to the supplied with digital signal of control first assessment unit 4a and the second assessment unit 4b.Analysis result generation unit 8, it generates the analysis result of single measurement.
The Blood Kit analytical approach of the embodiment of the present invention, comprises the steps: that (1) blood sample and reagent react at the first analysis area 1a and the second analysis area 1b; (2) simulating signal of the first analysis area 1a and the second analysis area 1b is generated by the first simulating signal measuring unit 2a and the second simulating signal 2b measuring unit; (3) the first digital signal and the second digital signal is generated by the first analog to digital converter 3a and the second analog to digital converter 3b respectively based on above-mentioned simulating signal; (4) the first digital signal and the second digital signal is stored by storer 6; (5) produced the first measured value and second measured value of blood sample based on above-mentioned first digital signal and the second digital signal by the first assessment unit 4a and the second assessment unit 4b; (6) comparator unit 5 compares the first measured value and the second measured value, judges whether its deviation is greater than specific threshold; (6.1) if this deviation is less than specific first threshold, analysis result generation unit 8 uses any one in the first measured value and the second measured value as measurement result value, terminates this and measures; (6.2) if this deviation is greater than specific first threshold, step (7) is carried out; (7) comparator unit 5 compares the first digital signal in storer 6 and the second digital signal, judges whether the deviation of the first digital signal and the second digital signal is less than specific Second Threshold; (7.1) if this deviation is greater than specific Second Threshold, then analysis result generation unit 8 provides the information of this measurement result mistake; (7.2) if this deviation is less than specific Second Threshold, represent that this deviation comes from assessment unit, carry out step (8); (8) by control module 7, first digital signal is inputted the second assessment unit 4b, the second digital signal inputs the first assessment unit 4a; Second assessment unit 4b generates the 3rd measured value based on the first digital signal, and the first assessment unit 4a generates the 4th measured value based on the second digital signal; (9) deviation S2:(9.1 deviation S1, described second measured value and described four measured value between of comparator unit 5 respectively between more described first measured value and described 4th measured value) if only there is S1 to be less than specific first threshold, represent that the measured value that the first assessment unit 1a provides is credible, then analysis result generation unit 8 provides the measured value of described first measured value as this blood sample; (9.2) if only there is S2 to be less than specific first threshold, represent that the measurement result that the second assessment unit 1b provides is credible, then analysis result generation unit 8 provides the measured value of described second measured value as this blood sample; (9.3) otherwise, represent cannot determine that whether the result that the first assessment unit 1a and the second assessment unit 1b provides credible, analysis result generation unit 8 provides the information of this measurement result mistake.
Below be only the preferred embodiment of the present invention, protection scope of the present invention be not only confined to above-described embodiment, all technical schemes belonged under thinking of the present invention all belong to protection scope of the present invention.For those skilled in the art, some improvements and modifications without departing from the principles of the present invention, should be considered as falling into protection scope of the present invention.
Claims (2)
1. a Blood Kit analytical approach, comprises the steps: that (1) blood sample and reagent react at the first analysis area and the second analysis area; (2) simulating signal of the first analysis area and the second analysis area is generated by the first simulating signal measuring unit and the second simulating signal measuring unit; (3) the first digital signal and the second digital signal is generated by the first analog to digital converter and the second analog to digital converter respectively based on above-mentioned simulating signal; (4) the first digital signal and the second digital signal is stored by storer; (5) the first measured value and second measured value of blood sample is produced by the first assessment unit and the second assessment unit based on above-mentioned first digital signal and the second digital signal; (6) comparator unit compares the first measured value and the second measured value, judges whether its deviation is greater than specific threshold; (6.1) if this deviation is less than specific first threshold, analysis result generation unit uses any one in the first measured value and the second measured value as measurement result value, terminates this and measures; (6.2) if this deviation is greater than specific first threshold, step (7) is carried out; (7) comparator unit compares the first digital signal in storer and the second digital signal, judges whether the deviation of the first digital signal and the second digital signal is less than specific Second Threshold; (7.1) if this deviation is greater than specific Second Threshold, then analysis result generation unit provides the information of this measurement result mistake; (7.2) if this deviation is less than specific Second Threshold, step (8) is carried out; (8) by control module, the first digital signal is inputted the second assessment unit, the second digital signal inputs the first assessment unit; Described second assessment unit generates the 3rd measured value based on the first digital signal, and described first assessment unit generates the 4th measured value based on the second digital signal; (9) deviation S2:(9.1 deviation S1, described second measured value and described four measured value between of comparator unit respectively between more described first measured value and described 4th measured value) if only there is S1 to be less than specific first threshold, then analysis result generation unit provides the measured value of described first measured value as this blood sample; (9.2) if only there is S2 to be less than specific first threshold, then analysis result generation unit provides the measured value of described second measured value as this blood sample; (9.3) otherwise, analysis result generation unit provides the information of this measurement result mistake.
2. a Blood Kit analytic system, it is for blood analysis method according to claim 1.
Priority Applications (2)
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| CN201710300287.3A CN106990232B (en) | 2016-01-01 | 2016-01-01 | Blood Kit analysis system and analysis method |
| CN201610000339.0A CN105388276B (en) | 2016-01-01 | 2016-01-01 | A kind of Blood Kit analysis system and analysis method |
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| CN201610000339.0A CN105388276B (en) | 2016-01-01 | 2016-01-01 | A kind of Blood Kit analysis system and analysis method |
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| CN201710300287.3A Division CN106990232B (en) | 2016-01-01 | 2016-01-01 | Blood Kit analysis system and analysis method |
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| CN201710300287.3A Active CN106990232B (en) | 2016-01-01 | 2016-01-01 | Blood Kit analysis system and analysis method |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108107195A (en) * | 2017-12-16 | 2018-06-01 | 黄友锋 | Blood sample analysis test method |
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- 2016-01-01 CN CN201610000339.0A patent/CN105388276B/en not_active Expired - Fee Related
- 2016-01-01 CN CN201710300287.3A patent/CN106990232B/en active Active
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| US4775237A (en) * | 1987-03-16 | 1988-10-04 | Innovative Medical Systems Corp. | Electro-optical detection system |
| CN1174996A (en) * | 1996-07-16 | 1998-03-04 | 曼海姆泊灵格股份公司 | Analysis system for testing small volume sample |
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| CN108107195A (en) * | 2017-12-16 | 2018-06-01 | 黄友锋 | Blood sample analysis test method |
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| CN106990232A (en) | 2017-07-28 |
| CN106990232B (en) | 2019-05-28 |
| CN105388276B (en) | 2017-08-04 |
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Inventor after: Qin Ling Inventor after: Xu Deying Inventor after: Sun Zhenzhen Inventor after: Wei Wei Inventor after: Zhang Yiting Inventor before: Huang Youfeng |
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Effective date of registration: 20170704 Address after: 471003 Henan Province, Luoyang city Jianxi District King Road No. 24 Applicant after: The First Affiliated Hospital of Henan University of Science and Technology Address before: 350000 Fuzhou, Gulou District, Fujian City, the new right road, No. 29 Applicant before: Huang Youfeng |
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