CN105380698A - Nanometer electrospinning thrombus exsector - Google Patents
Nanometer electrospinning thrombus exsector Download PDFInfo
- Publication number
- CN105380698A CN105380698A CN201510865034.1A CN201510865034A CN105380698A CN 105380698 A CN105380698 A CN 105380698A CN 201510865034 A CN201510865034 A CN 201510865034A CN 105380698 A CN105380698 A CN 105380698A
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- China
- Prior art keywords
- thrombectomy device
- microtubular
- shape memory
- thrombosis
- nanometer
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
- A61B2017/00238—Type of minimally invasive operation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22038—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with a guide wire
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22079—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with suction of debris
Abstract
The invention discloses a nanometer electrospinning thrombus exsector. The thrombus exsector comprises a guide wire, a shape memory skeleton, a capture net membrane and a tungsten-wire spring coil; the capture net membrane is sprayed on the shape memory skeleton through a nanometer high-voltage electrospinning technology, the two ends of a nickel-titanium memory alloy wire of the shape memory skeleton are welded to the tail end of the guide wire and the front section of the tungsten-wire spring coil respectively, the nickel-titanium memory alloy wire of the shape memory skeleton is shaped like a straight line in a micro catheter, is of an arc-shaped structure without angles after being pushed out of the micro catheter and is capable of being retracted and pushed out of the micro catheter repeatedly, the capture net membrane is a grid-shaped thin membrane, the tungsten-wire spring coil is a spring coil which is formed by winding a tungsten wire of 0.02-0.10 mm and has the outer diameter of 0.15-0.35 mm. The nanometer electrospinning thrombus exsector can pass through intracranial and extracranial circuitous blood vessels, repeatedly cut and shatter thrombi in blood vessel cavities with different diameters, capture the thrombi and remove the thrombi out of a human body.
Description
Technical field
The present invention relates to technical field of medical instruments, relate to a kind of nanometer Electrospun thrombectomy device specifically.
Background technology
Cerebral thrombosis is a kind of common ischemic cerebrovascular, its sickness rate and disability rate are all higher, tortuous and Ink vessel transfusing generation thrombosis that caliber is tiny in brain, namely the thrombosis in cerebral artery vessel, it is the acute ischemia of a kind of human central nervous system burst, the cerebral tissue of ischemic area will therefore function generation obstacle or lose its function, patient is in threaten life and heavy sensation of the whole body will to survive the emergency of function.
When cerebral thrombosis occurs, because local brain tissue is because of angiemphraxis ischemia, neural activity and important physiological function are on the hazard, and medical object removes endovascular obstruction as early as possible, makes blood flow unobstructed.But, clinical medical treatment of generally implementing cannot remove thrombosis, unblocking fast at present, except weak curative effect, also there is the restriction of therapeutic time window, Tissue reperfusion injury may be caused, even organize hemorrhage serious consequence in its dilatation taked, anticoagulant, thromboembolism treatment.The sucking-off longed for of suction therapy block thrombosis then many because of cannot surpass selectively arrive diseased region and suction effect not good and be difficult to prove effective.Thus, the acute organ ischemia that in brain, thin vessels acute occlusion causes is still the difficult problem in clinical medicine treatment.At present, the thrombectomy device used clinically, does not substantially have seizure, removes the function of thrombosis.
Summary of the invention
For deficiency of the prior art, the technical problem to be solved in the present invention there are provided a kind of nanometer Electrospun thrombectomy device.This thrombectomy device, by the inside and outside tortuous blood vessel of cranium, repeatedly cuts at different-diameter Endovascular, pulverizes thrombosis, and by thrombosis seizure, removing to external.
For solving the problems of the technologies described above, the present invention is realized by following scheme: a kind of nanometer Electrospun thrombectomy device, described thrombectomy device comprises seal wire, shape memory skeleton, catch nethike embrane and Tungsten coil, described seizure nethike embrane adopts nanometer high-tension electricity spinning technique to be sprayed on shape memory skeleton, the Ultimum Ti silk two ends of described shape memory skeleton, be welded in the end of seal wire and the leading portion of Tungsten coil respectively, the 20-30cm place, seal wire front end of described thrombectomy device adopts electrochemical etch techniques to be processed as diameter 0.1-0.2mm taper gradually thin segment, the Ultimum Ti silk of described shape memory skeleton is linearly in microtubular, be acerous arcuate structure after releasing microtubular, and can repeatedly reclaim and release microtubular, described seizure nethike embrane is a kind of mesh-like film, film thickness is 10-15um, sizing grid is less than 15um, described Tungsten coil turns to 0.02-0.10mm tungsten filament the turn that external diameter is 0.15-0.35mm.
Further, described seal wire diameter is 0.15-0.35mm, and length is 1.5-2.5m.
Further, the Ultimum Ti filament diameter of described shape memory skeleton is 0.15mm.
Further, described seizure nethike embrane is made into grid thin film by polyurethane material through nanometer high-tension electricity spinning technique.
Further, the nethike embrane of described seizure nethike embrane can stop that thrombosis passes through, but allows hemocyte to pass through.
An operational approach for nanometer Electrospun thrombectomy device, the method comprises the following steps:
Step 1, after conventional femoral artery puncture success, insert catheter sheath, 5F to 8F collecting pipe is delivered to common carotid artery, internal carotid artery radiography under the perspective of x-ray, the position of the clear and definite cerebral thrombosis of DSA radiography and size, measure the caliber of thrombosis proximal vessel, the thrombectomy device that selection size specification is suitable and microtubular;
Step 2, under the guiding of seal wire, thrombectomy device, near the near-end of thrombosis, is sent into through microtubular by microtubular, and the Tungsten coil of thrombectomy device leading portion exposes outside microtubular;
Step 3, under the Tungsten coil of thrombectomy device leading portion and the cooperation of microtubular, microtubular is by thrombosis, and sent in microtubular by thrombectomy device, thrombectomy device is curved to be opened, and catches nethike embrane smooth opening;
Step 4, the seal wire of tractive, rotation thrombectomy device then, by thrombectomby, pulverizing, and is collected in seizure nethike embrane;
Step 5, post-tensioning microtubular and thrombectomy device, draw in thrombosis in collecting pipe, withdraw from external in the lump together with collecting pipe simultaneously;
Step 6, aforesaid operations repeats, to ensure that thrombectomby is complete.
Relative to prior art, the invention has the beneficial effects as follows: for solving the technical problem that intracranial thin vessels acute occlusion treatment clinically exists, nanometer Electrospun thrombectomy device provided by the invention is by the inside and outside tortuous blood vessel of cranium, repeatedly cut at different-diameter Endovascular, pulverize thrombosis, and by thrombosis seizure, removing to external.Shape memory skeleton has good x-ray developability, and acerous arcuate structure can reduce the damage of tunica intima, can excise fast simultaneously, pulverize thrombosis.It is latticed for catching nethike embrane, and sizing grid is suitable for, and it can catch thrombosis and avoid distal embolization, allows hemocyte to pass through simultaneously.Thrombectomy device of the present invention can repeatedly pushed forward and post-tensioning reclaim in tiny microtubular, excises thrombosis rapidly, removes angiemphraxis, reach protection cerebral tissue, reduce the object of complication.
Accompanying drawing explanation
In order to be illustrated more clearly in the embodiment of the present invention or technical scheme of the prior art, be briefly described to the accompanying drawing used required in embodiment or description of the prior art below, apparently, accompanying drawing in the following describes is only some embodiments of the present invention, for those of ordinary skill in the art, under the prerequisite not paying creative work, other accompanying drawing can also be obtained according to these accompanying drawings.
Fig. 1 is thrombectomy device structural representation of the present invention.
Fig. 2 be the present invention catch nethike embrane pave launch after schematic diagram.
Fig. 3 is that in the embodiment of the present invention 1, thrombectomy device inserts microtubular, microtubular inserts collecting pipe schematic diagram.
Labelling in accompanying drawing: seal wire 1, shape memory skeleton 2, seizure nethike embrane 3, Tungsten coil 4, microtubular 5, collecting pipe 6.
Detailed description of the invention
Below in conjunction with accompanying drawing, the preferred embodiments of the present invention are described in detail, can be easier to make advantages and features of the invention be readily appreciated by one skilled in the art, thus more explicit defining is made to protection scope of the present invention.
Please refer to accompanying drawing 1 ~ 2, a kind of nanometer Electrospun thrombectomy device, described thrombectomy device comprises seal wire 1, shape memory skeleton 2, catch nethike embrane 3 and Tungsten coil 4, described seizure nethike embrane 3 adopts nanometer high-tension electricity spinning technique to be sprayed on shape memory skeleton 2, the Ultimum Ti filament diameter of described shape memory skeleton 2 is 0.15mm, the Ultimum Ti silk two ends of described shape memory skeleton 2, be welded in the end of seal wire 1 and the leading portion of Tungsten coil 4 respectively, described seal wire 1 diameter is 0.15-0.35mm, length is 1.5-2.5m, the 20-30cm place, seal wire 1 front end of described thrombectomy device adopts electrochemical etch techniques to be processed as diameter 0.1-0.2mm taper gradually thin segment, the Ultimum Ti silk of described shape memory skeleton 2 is linearly in microtubular, be acerous arcuate structure after releasing microtubular, and can repeatedly reclaim and release microtubular, described seizure nethike embrane 3 is a kind of mesh-like films, film thickness is 10-15um, sizing grid is less than 15um, described seizure nethike embrane 3 is made into grid thin film by polyurethane material through nanometer high-tension electricity spinning technique, the large I of its nethike embrane stops that thrombosis passes through, but allow hemocyte to pass through, described Tungsten coil 4 turns to 0.02-0.10mm tungsten filament the turn that external diameter is 0.15-0.35mm.For solving the technical problem that intracranial thin vessels acute occlusion treatment clinically exists, nanometer Electrospun thrombectomy device provided by the invention is by the inside and outside tortuous blood vessel of cranium, repeatedly cut at different-diameter Endovascular, pulverize thrombosis, and by thrombosis seizure, removing to external.Shape memory skeleton 2 has good x-ray developability, and acerous arcuate structure can reduce the damage of tunica intima, can excise fast simultaneously, pulverize thrombosis.Catch nethike embrane 3 in latticed, sizing grid is suitable for, and it can catch thrombosis and avoid distal embolization, allows hemocyte to pass through simultaneously.Thrombectomy device of the present invention can repeatedly pushed forward and post-tensioning reclaim in tiny microtubular 5, excises thrombosis rapidly, removes angiemphraxis, reach protection cerebral tissue, reduce the object of complication.
Embodiment 1: please refer to accompanying drawing 3, the operational approach of a kind of nanometer Electrospun thrombectomy device of the present invention, it is characterized in that, the method comprises the following steps:
Step 1, after conventional femoral artery puncture success, insert catheter sheath, 5F to 8F collecting pipe 6 is delivered to common carotid artery, internal carotid artery radiography under the perspective of x-ray, the position of the clear and definite cerebral thrombosis of DSA radiography and size, measure the caliber of thrombosis proximal vessel, the thrombectomy device that selection size specification is suitable and microtubular 5;
Step 2, under the guiding of seal wire, thrombectomy device, near the near-end of thrombosis, is sent into through microtubular 5 by microtubular 5, and the Tungsten coil 4 of thrombectomy device leading portion exposes outside microtubular 5;
Step 3, under the Tungsten coil 4 of thrombectomy device leading portion and the cooperation of microtubular 5, microtubular 5 is by thrombosis, and sent in microtubular 5 by thrombectomy device, thrombectomy device is curved to be opened, and catches nethike embrane 3 smooth opening;
Step 4, the seal wire 1 of tractive, rotation thrombectomy device then, by thrombectomby, pulverizing, and is collected in seizure nethike embrane 3;
Step 5, post-tensioning microtubular 5 and thrombectomy device, draw in thrombosis in collecting pipe, withdraw from external in the lump together with collecting pipe simultaneously;
Step 6, aforesaid operations repeats, to ensure that thrombectomby is complete.
The foregoing is only the preferred embodiment of the present invention; not thereby the scope of the claims of the present invention is limited; every utilize description of the present invention and accompanying drawing content to do equivalent structure or equivalent flow process conversion; or be directly or indirectly used in other relevant technical field, be all in like manner included in scope of patent protection of the present invention.
Claims (6)
1. a nanometer Electrospun thrombectomy device, it is characterized in that: described thrombectomy device comprises seal wire (1), shape memory skeleton (2), catch nethike embrane (3) and Tungsten coil (4), described seizure nethike embrane (3) adopts nanometer high-tension electricity spinning technique to be sprayed on shape memory skeleton (2), the Ultimum Ti silk two ends of described shape memory skeleton (2), be welded in the end of seal wire (1) and the leading portion of Tungsten coil (4) respectively, the 20-30cm place, seal wire (1) front end of described thrombectomy device adopts electrochemical etch techniques to be processed as diameter 0.1-0.2mm taper gradually thin segment, the Ultimum Ti silk of described shape memory skeleton (2) is linearly in microtubular, be acerous arcuate structure after releasing microtubular, and can repeatedly reclaim and release microtubular, described seizure nethike embrane (3) is a kind of mesh-like film, film thickness is 10-15um, sizing grid is less than 15um, described Tungsten coil (4) turns to 0.02-0.10mm tungsten filament the turn that external diameter is 0.15-0.35mm.
2. a kind of nanometer Electrospun thrombectomy device according to claim 1, it is characterized in that: described seal wire (1) diameter is 0.15-0.35mm, length is 1.5-2.5m.
3. a kind of nanometer Electrospun thrombectomy device according to claim 1, is characterized in that: the Ultimum Ti filament diameter of described shape memory skeleton (2) is 0.15mm.
4. a kind of nanometer Electrospun thrombectomy device according to claim 1, is characterized in that: described seizure nethike embrane (3) is made into grid thin film by polyurethane material through nanometer high-tension electricity spinning technique.
5. a kind of nanometer Electrospun thrombectomy device according to claim 1 or 4, is characterized in that: the nethike embrane of described seizure nethike embrane (3) can stop that thrombosis passes through, but allows hemocyte to pass through.
6. an operational approach for nanometer Electrospun thrombectomy device, is characterized in that, the method comprises the following steps:
Step 1, after conventional femoral artery puncture success, insert catheter sheath, 5F to 8F collecting pipe (6) is delivered to common carotid artery, internal carotid artery radiography under the perspective of x-ray, the position of the clear and definite cerebral thrombosis of DSA radiography and size, measure the caliber of thrombosis proximal vessel, the thrombectomy device that selection size specification is suitable and microtubular (5);
Step 2, under the guiding of seal wire, microtubular (5) is near the near-end of thrombosis, and sent into through microtubular (5) by thrombectomy device, the Tungsten coil (4) of thrombectomy device leading portion exposes microtubular (5) outward;
Step 3, under the Tungsten coil (4) of thrombectomy device leading portion and the cooperation of microtubular (5), thrombectomy device, by thrombosis, is sent by microtubular (5) in microtubular (5), and thrombectomy device is curved to be opened, and catches nethike embrane (3) smooth opening;
Step 4, the seal wire (1) of tractive, rotation thrombectomy device then, by thrombectomby, pulverizing, and is collected in seizure nethike embrane (3);
Step 5, post-tensioning microtubular (5) and thrombectomy device, draw in thrombosis in collecting pipe, withdraw from external in the lump together with collecting pipe simultaneously;
Step 6, aforesaid operations repeats, to ensure that thrombectomby is complete.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510865034.1A CN105380698A (en) | 2015-12-01 | 2015-12-01 | Nanometer electrospinning thrombus exsector |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510865034.1A CN105380698A (en) | 2015-12-01 | 2015-12-01 | Nanometer electrospinning thrombus exsector |
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| CN105380698A true CN105380698A (en) | 2016-03-09 |
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| CN201510865034.1A Pending CN105380698A (en) | 2015-12-01 | 2015-12-01 | Nanometer electrospinning thrombus exsector |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111134775A (en) * | 2020-01-22 | 2020-05-12 | 北京弘海微创科技有限公司 | Thrombus collector |
| CN111134786A (en) * | 2020-01-22 | 2020-05-12 | 北京弘海微创科技有限公司 | Thrombus breaker |
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| US6171327B1 (en) * | 1999-02-24 | 2001-01-09 | Scimed Life Systems, Inc. | Intravascular filter and method |
| CN1331956A (en) * | 2001-07-06 | 2002-01-23 | 周星 | Reusable temporary thrombus filter |
| US20050177186A1 (en) * | 2002-04-01 | 2005-08-11 | Gore Enterprise Holdings, Inc. | Endoluminal devices |
| CN202619801U (en) * | 2012-05-14 | 2012-12-26 | 湖南依微迪医疗器械有限公司 | Cerebral thrombosis resecting device |
| CN102970938A (en) * | 2010-04-13 | 2013-03-13 | 访问点技术公司 | Embolic material excision trapping device |
| CN104398318A (en) * | 2014-12-02 | 2015-03-11 | 何凡 | Nanometer electro-spinning tectorial membrane etching support and method for curing intracranial aneurysm |
| CN104582607A (en) * | 2012-08-14 | 2015-04-29 | W.L.戈尔及同仁股份有限公司 | Devices and systems for thrombus treatment |
| CN205163174U (en) * | 2015-12-01 | 2016-04-20 | 李启洋 | Nanometer electricity spinning thrombus resectoscope |
-
2015
- 2015-12-01 CN CN201510865034.1A patent/CN105380698A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6171327B1 (en) * | 1999-02-24 | 2001-01-09 | Scimed Life Systems, Inc. | Intravascular filter and method |
| CN1331956A (en) * | 2001-07-06 | 2002-01-23 | 周星 | Reusable temporary thrombus filter |
| US20050177186A1 (en) * | 2002-04-01 | 2005-08-11 | Gore Enterprise Holdings, Inc. | Endoluminal devices |
| CN102970938A (en) * | 2010-04-13 | 2013-03-13 | 访问点技术公司 | Embolic material excision trapping device |
| CN202619801U (en) * | 2012-05-14 | 2012-12-26 | 湖南依微迪医疗器械有限公司 | Cerebral thrombosis resecting device |
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| CN104398318A (en) * | 2014-12-02 | 2015-03-11 | 何凡 | Nanometer electro-spinning tectorial membrane etching support and method for curing intracranial aneurysm |
| CN205163174U (en) * | 2015-12-01 | 2016-04-20 | 李启洋 | Nanometer electricity spinning thrombus resectoscope |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111134775A (en) * | 2020-01-22 | 2020-05-12 | 北京弘海微创科技有限公司 | Thrombus collector |
| CN111134786A (en) * | 2020-01-22 | 2020-05-12 | 北京弘海微创科技有限公司 | Thrombus breaker |
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