CN105286883A - Pulse hemoglobin concentration non-invasive measurement method and device - Google Patents
Pulse hemoglobin concentration non-invasive measurement method and device Download PDFInfo
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- CN105286883A CN105286883A CN201510576398.8A CN201510576398A CN105286883A CN 105286883 A CN105286883 A CN 105286883A CN 201510576398 A CN201510576398 A CN 201510576398A CN 105286883 A CN105286883 A CN 105286883A
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Abstract
The invention discloses a pulse hemoglobin concentration non-invasive measurement method and device. The method comprises the following steps of a, synchronously collecting three photoelectric pulse wave signals in different wavelengths in a period of time; b, extracting the feature values of all of any two groups of photoelectric pulse wave signals by using a linear regression algorithm; c, calculating the oxyhemoglobin concentration and the deoxyhemoglobin concentration according to the feature values; and d, adding the oxyhemoglobin concentration and the deoxyhemoglobin concentration to obtain the hemoglobin concentration. The pulse hemoglobin concentration non-invasive measurement device comprises a photoelectric pulse sensor used for collecting signals in the step a, wherein an output interface of the photoelectric pulse sensor is connected in series with a signal conditioning module and a microprocessor; after the photoelectric pulse wave signals are obtained by the microprocessor, the steps b, c and d are executed; and the hemoglobin concentration is obtained. The measurement method is simple, convenient, fast and reliable; the non-invasive, real-time, continuous and fast measurement can be performed; and the application and the popularization are convenient.
Description
Technical field
The present invention relates to hemoglobin detection field, specifically a kind of pulse hemoglobin concentration non-invasive measurement method and device.
Background technology
Hemoglobin (Hemoglobin, HGB) is the main protein of human erythrocyte, and its main Physiological Function is transport oxygen and carbon dioxide, and plays cushioning effect to acidic materials, and the acid-base balance participated in body regulates.
The detection method that HGB concentration is commonly used mainly contains cyanmethemoglobin method (HiCN) and photoelectric colorimetry.HiCN method a kind ofly has wound, manual detection method, ICSH (ICSH) is using the golden standard of this method as judgement hemoglobin concentration, but due to the impact of the factors such as toxicity, complexity and real-time, the method is infeasible in clinical laboratory environment.Blood analyser is the widely used a kind of HGB automatic checkout equipment in the current whole world, and what it adopted is photoelectric colorimetry, and it can provide the measurement result suitable with HiCN method.Identical with HiCN method, it is also a kind of method having wound, and each measurement all needs to take a blood sample to patient, and exist and make patient and coroner infect the risk of bloodborne pathogens, and detect consumable goods costly, detection time is long.In addition, this equipment can not carry out HGB concentration continuous print, real-time monitoring.And modern medicine study shows, for various critical patient in clinical, particularly hemorrhagic shock and patient with operation, fast, in continuous print, real-time monitoring of blood, the change of HGB concentration can judge change of illness state in time and make correct therapeutic scheme, as reduced the blood transfusion number of times of surgery, the bleeding etc. that Timeliness coverage is postoperative.As can be seen here, realize that human body HGB concentration is noninvasive, fast, continuous print, real-time detection or monitoring have very high clinical value and market value.
Summary of the invention
The object of the present invention is to provide a kind of pulse hemoglobin concentration non-invasive measurement method and device, human pulse hemoglobin concentration noinvasive can be realized by the method and device, measure in real time, continuously and fast, facilitate application.
The technical solution adopted for the present invention to solve the technical problems is:
A kind of pulse hemoglobin concentration non-invasive measurement method, comprises the following steps:
In order to realize said method, the present invention also provides a kind of pulse hemoglobin concentration non-invasive measurement device, comprise photoelectric sphyg sensor, photoelectric sphyg sensor output interface is in series with Signal-regulated kinase and microprocessor successively, the power supply that microprocessor periphery is also provided with the output unit that is connected with microprocessor and powers for measuring device;
Described photoelectric sphyg sensor is by the Photoelectric Pulse Wave Signal of three different wave lengths in Microprocessor S3C44B0X synchronous acquisition a period of time;
Described Signal-regulated kinase carries out A/D conversion and filtering noise reduction process to Photoelectric Pulse Wave Signal, and the Photoelectric Pulse Wave Signal after process is sent to microprocessor;
Described microprocessor performs following steps:
Further, described output unit comprises the memorizer, display screen and the outputting communication interface that are connected with microprocessor.
The invention has the beneficial effects as follows, linear regression algorithm is utilized to extract the eigenvalue of all any two groups of Photoelectric Pulse Wave Signals in three different wave lengths, and according to its eigenvalue calculation HbO2 Oxyhemoglobin concentration and deoxy-hemoglobin concentrations, again HbO2 Oxyhemoglobin concentration is added with deoxy-hemoglobin concentrations and namely obtains hemoglobin concentration, measuring method is simple and convenient, fast and reliable, noinvasive can be carried out, measure in real time, continuously and fast, facilitate application.
Accompanying drawing explanation
Below in conjunction with drawings and Examples, the present invention is further described:
Fig. 1 is workflow schematic diagram of the present invention;
Fig. 2 is electrical principle block diagram of the present invention.
Detailed description of the invention
As shown in Figure 1, the invention provides a kind of pulse hemoglobin concentration non-invasive measurement method, comprise the following steps:
Shown in composition graphs 2, in order to realize said method, the present invention also provides a kind of pulse hemoglobin concentration non-invasive measurement device, comprise photoelectric sphyg sensors A, the output interface of photoelectric sphyg sensors A is in series with Signal-regulated kinase B and microprocessor C successively, the power supply E that microprocessor C periphery is also provided with the output unit D that is connected with microprocessor C and powers for measuring device;
Described photoelectric sphyg sensor E comprises the luminescent device and at least 1 photoelectric receiving device that can launch at least 3 wavelength, can adopt integrated three wave length LED and photoelectric receiving tube, such as HSE660.905.940-P4 and HSPD940-112NP3; Photoelectric sphyg sensor E is controlled by microprocessor C, puts on the position such as finger tip or ear-lobe of human body, the Photoelectric Pulse Wave Signal of three different wave lengths in synchronous acquisition a period of time;
Described Signal-regulated kinase B carries out A/D conversion and filtering noise reduction process to Photoelectric Pulse Wave Signal, and the Photoelectric Pulse Wave Signal after process is sent to microprocessor C;
Described microprocessor C performs following steps:
The hemoglobin concentration tHb calculated sends to output unit D to carry out exporting by microprocessor C, Storage & Display.Output unit D comprises the memorizer, display screen and the outputting communication interface that are connected with microprocessor C, and outputting communication interface can adopt the multiple communication modes such as UART, USB and bluetooth and external communication to transmit the hemoglobin concentration calculated.
The above is only preferred embodiment of the present invention, not does any pro forma restriction to the present invention; Any those of ordinary skill in the art, do not departing under technical solution of the present invention ambit, the Method and Technology content of above-mentioned announcement all can be utilized to make many possible variations and modification to technical solution of the present invention, or be revised as the Equivalent embodiments of equivalent variations.Therefore, every content not departing from technical solution of the present invention, according to technical spirit of the present invention to any simple modification made for any of the above embodiments, equivalent replacement, equivalence change and modification, all still belongs in the scope of technical solution of the present invention protection.
Claims (3)
1. a pulse hemoglobin concentration non-invasive measurement method, is characterized in that, said method comprising the steps of:
。
2. a pulse hemoglobin concentration non-invasive measurement device, it is characterized in that, described measuring device comprises photoelectric sphyg sensor, photoelectric sphyg sensor output interface is in series with Signal-regulated kinase and microprocessor successively, the power supply that microprocessor periphery is also provided with the output unit that is connected with microprocessor and powers for measuring device;
Described photoelectric sphyg sensor is by the Photoelectric Pulse Wave Signal of three different wave lengths in Microprocessor S3C44B0X synchronous acquisition a period of time;
Described Signal-regulated kinase carries out A/D conversion and filtering noise reduction process to Photoelectric Pulse Wave Signal, and the Photoelectric Pulse Wave Signal after process is sent to microprocessor;
Described microprocessor performs following steps:
。
3. a kind of pulse hemoglobin concentration non-invasive measurement device according to claim 2, it is characterized in that, described output unit comprises the memorizer, display screen and the outputting communication interface that are connected with microprocessor.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510576398.8A CN105286883A (en) | 2015-09-11 | 2015-09-11 | Pulse hemoglobin concentration non-invasive measurement method and device |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510576398.8A CN105286883A (en) | 2015-09-11 | 2015-09-11 | Pulse hemoglobin concentration non-invasive measurement method and device |
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| CN105286883A true CN105286883A (en) | 2016-02-03 |
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| CN201510576398.8A Pending CN105286883A (en) | 2015-09-11 | 2015-09-11 | Pulse hemoglobin concentration non-invasive measurement method and device |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107569237A (en) * | 2017-09-14 | 2018-01-12 | 天津科技大学 | The measuring method and device of Non-invasive detection hemoglobin level |
| CN112545461A (en) * | 2020-12-05 | 2021-03-26 | 深圳市美的连医疗电子股份有限公司 | Method, device and system for detecting non-invasive hemoglobin concentration value and computer readable storage medium |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1335756A (en) * | 1998-12-01 | 2002-02-13 | 克里蒂凯尔系统公司 | Direct to digital oximeter and method for calculating oxygenation levels |
| US20030023140A1 (en) * | 1989-02-06 | 2003-01-30 | Britton Chance | Pathlength corrected oximeter and the like |
| CN1911172A (en) * | 2006-08-25 | 2007-02-14 | 清华大学 | Method for testing absolute volume of concentration of oxidized hemoglobin and reduced hemoglobin in human tissue |
-
2015
- 2015-09-11 CN CN201510576398.8A patent/CN105286883A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030023140A1 (en) * | 1989-02-06 | 2003-01-30 | Britton Chance | Pathlength corrected oximeter and the like |
| CN1335756A (en) * | 1998-12-01 | 2002-02-13 | 克里蒂凯尔系统公司 | Direct to digital oximeter and method for calculating oxygenation levels |
| CN1911172A (en) * | 2006-08-25 | 2007-02-14 | 清华大学 | Method for testing absolute volume of concentration of oxidized hemoglobin and reduced hemoglobin in human tissue |
Non-Patent Citations (2)
| Title |
|---|
| 张根选 等: "一种高效实时脉搏血氧监测系统的研究", 《激光与红外》 * |
| 石波 等: "线性回归算法提取脉搏血氧特征值初步验证", 《中国医学物理学杂志》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107569237A (en) * | 2017-09-14 | 2018-01-12 | 天津科技大学 | The measuring method and device of Non-invasive detection hemoglobin level |
| CN112545461A (en) * | 2020-12-05 | 2021-03-26 | 深圳市美的连医疗电子股份有限公司 | Method, device and system for detecting non-invasive hemoglobin concentration value and computer readable storage medium |
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Application publication date: 20160203 |