CN105106980A - Coupling lubricating agent for rectum B-ultrasonic examination for large livestock and preparation method and application method - Google Patents
Coupling lubricating agent for rectum B-ultrasonic examination for large livestock and preparation method and application method Download PDFInfo
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- CN105106980A CN105106980A CN201510643929.0A CN201510643929A CN105106980A CN 105106980 A CN105106980 A CN 105106980A CN 201510643929 A CN201510643929 A CN 201510643929A CN 105106980 A CN105106980 A CN 105106980A
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Abstract
The invention relates to a coupling lubricating agent for a rectum B-ultrasonic examination on a large livestock as well as a preparation method and an application method. The invention provides a coupling agent which is suitable for the rectum B-ultrasonic examination for the large livestock. The coupling lubricating agent is prepared from 10 to 15 parts by weight of sodium dodecyl sulfate and 2 to 4 parts by weight of cocoanut fatty acid diethanolamide as well as other raw materials. The invention also relates the relevant preparation method and application method. The coupling lubricating agent is suitable for the rectum examination and particularly suitable for the rectum B-ultrasonic examination of the large livestock such as donkeys, horses, cattle and the like.
Description
Technical field
The present invention relates to a kind of large domestic animal Ultrasonography to be coupled lubricant and preparation method and using method.
Background technology
The use of couplant can reduce the air of Ultrasonic-B probe and body surface, makes B ultrasonic image more without interruption clear.Generally ultrasound diagnosis is just carried out at body surface, existing couplant can satisfy the demands on the market, but the Ultrasonographies such as some large domestic animal such as horse, donkey, cattle require that examiner must enter the scanning that domestic animal rectum carries out uterus and ovary by hand-held Ultrasonic-B probe, this just has certain requirement to the lubricant effect of couplant, do not have existing coupling can play again coupling or the lubricant of examination per rectum lubrication on the market, common couplant can not meet arm enters rectum lubrication needs by anus.Further, be easy in examination per rectum process cause rectal mucosal skin lesion, common lubricant does not all have bactericidal action, is so just easy to the wound infection after causing domestic animal examination per rectum, or the cross infection of domestic animal recial disease.
The inner walls of rectums of the large domestic animal such as donkey, horse, cattle is huge, and fold is many, and when carrying out Ultrasonography, Ultrasonic-B probe and rectal wall have air gap, very easily disturbs by air gap during rectum B ultrasonic.
Summary of the invention
The technical problem to be solved in the present invention is the above-mentioned defect how overcoming prior art, provides a kind of large domestic animal Ultrasonography to be coupled lubricant and preparation method and using method.
For solving the problems of the technologies described above, the present invention's large domestic animal Ultrasonography coupling lubricant is by the card ripple of 0.3 ~ 0.6 weight portion; Three Sodium ethylate of 0.1 ~ 0.5 weight portion; The sodium lauryl sulphate of 10 ~ 15 weight portions; The sodium citrate of 0.3 ~ 0.6 weight portion; The povidone iodine of 3 ~ 5 weight portions; The cocoanut fatty acid diethanolamide of 2 ~ 4 weight portions; The carboxyethyl cellulose of 4-7 weight portion is received and the deionized water of 65 ~ 75 weight portions is made.Design like this, as long as gained coupling lubricant a bit, just can fill the hands of Ultrasonic-B probe and operator, high lubricating effect, not easily air-dry, and gained B ultrasonic image is more clear.
Composition character required for the present invention and function as follows:
(1) sodium lauryl sulphate (SDS), is a kind of white or faint yellow micro-sticky thing, belongs to anion surfactant.Soluble in water, good with anion, nonionic compatibility, there is good emulsifying, foaming, infiltration, decontamination and dispersive property.
(2) sodium citrate, also known as sodium citrate.Colourless or white crystals granule or crystalline powder, odorless, salty in the mouth, cool, soluble in water, be insoluble in ethanol, safety non-toxic performance.Owing to preparing the raw material basic source of sodium citrate in grain, be thus perfectly safe reliable, can not harm be produced to human health.The United Nations grain farmer and World Health Organization (WHO) do not impose any restrictions its daily intake, can think that these product belong to No Poison.Make acidity agent, antiseptic and antioxidant in the present invention.
(3) povidone iodine, also known as BETADINE.Be yellowish-brown to rufous amorphous powder, water soluble and ethanol.Discharge iodine gradually in a solvent, play a kind of slow releasing function, to keep the sterilizing power of long period.Its powerful bactericidal mechanism is the active group of oxidation pathogen oleo stock albumen, and can be combined with the amino of protein and make its degeneration, thus can effectively kill the pathogen such as antibacterial, spore, fungus, virus and protozoon.Have sterilizing power strong, bactericidal range is wide, and zest is minimum, and xanthochromia is light, and easy cleaning, without features such as anaphylaxiss.Quick killing action is had to hundreds of antibacterial, viruses etc. such as staphylococcus aureus, escherichia coli, bacillus pyocyaneus, gonococcus, Candida albicans.
(4) cocoanut fatty acid diethanolamide (6501), is a kind of faint yellow to amber thick liquid, belongs to non-ionic surface active agent, time acid and anion surfactant compatibility thickening effect obvious especially.Soluble in water, there is good foaming, steady bubble, function such as infiltration decontamination, anti-hard water etc.
(5) sodium hydroxyethlcellulose is a kind of stabilizing agent, thickening agent of doing food processing.There is good water solublity, compatibility and stability.
(6) card ripple, also carbomer (carbomer) is claimed, be cross-linked with acrylic acid the acrylic acid crosslinked resin obtained with tetramethylolmethane etc., it is the very important rheology control agent of a class, card ripple after neutralization is outstanding gel-type vehicle, and have the important use such as thickening, suspension, technique is simple, good stability, is widely used in emulsion, cream frost, gel.
(7) triethanolamine, colourless to pale yellow transparent thick liquid, micro-have ammonia taste, as the acid-base neutralization agent preparing carbomer gel.
The preparation method of the present invention's large domestic animal Ultrasonography coupling lubricant, comprises the following steps:
(1) the card ripple getting 0.3 ~ 0.6 weight portion adds in the deionized water of 30 weight portions, and heating in water bath Keep agitation 20min, is cooled to room temperature, obtains A liquid;
(2) three Sodium ethylate getting 0.1 ~ 0.5 weight portion are dissolved in A liquid mix homogeneously, obtain B liquid;
(3) sodium citrate of the sodium lauryl sulphate and 0.3 ~ 0.6 weight portion of getting 10 ~ 15 weight portions adds in the deionized water of 35 ~ 45 weight portions, is heated to 70 ~ 80 DEG C, is cooled to room temperature after dissolving, obtain C liquid;
(4) povidone iodine getting 3 ~ 5 weight portions is dissolved in mix homogeneously in C liquid, obtains D liquid;
(5) cocoanut fatty acid diethanolamide getting 2 ~ 4 weight portions is incorporated in D liquid, and mix homogeneously obtains E liquid;
(6) sodium hydroxyethlcellulose getting 4-7 weight portion adds in E liquid and is uniformly mixed, and obtains F liquid, then adds (2) gained B liquid, be uniformly mixed, obtain product of the present invention.
The using method of the present invention's large domestic animal Ultrasonography coupling lubricant, is characterized in that: prepare aforementioned large domestic animal Ultrasonography coupling lubricant before use, and be finished in four hours.
The using method of the present invention's large domestic animal Ultrasonography coupling lubricant, is characterized in that: first prepare B liquid and F liquid respectively in proportion, and preserves shady and cool place respectively, before use by B liquid and F liquid, and mix homogeneously, and be finished in four hours.
The present invention adopts anion surfactant and non-ionic surface active agent, the gap of Ultrasonic-B probe and rectal wall can be filled, get rid of air gap interference, effectively can play in Ultrasonography the effect being coupled, lubricating, consumption is few, not easily air-dry, required raw material is bought convenient, cheap, is applicable to the examination per rectum of various large domestic animal.
Coordinate the povidone iodine with efficient sterilizing, disinfective action, and the sodium hydroxyethlcellulose of pure natural moistening skin-care effect, effectively can prevent the probability of livestock intestinal tract infection and cross infection in examination per rectum.
The present invention adopts anion surfactant and non-ionic surface active agent, the gap of Ultrasonic-B probe and rectal wall can be filled, get rid of air gap interference, effectively can play in Ultrasonography the effect being coupled, lubricating, consumption is few, not easily air-dry, required raw material is bought convenient, cheap, is applicable to the examination per rectum of various large domestic animal.
Coordinate the povidone iodine with efficient sterilizing, disinfective action, and the sodium hydroxyethlcellulose of pure natural moistening skin-care effect, effectively can prevent the probability of livestock intestinal tract infection and cross infection in examination per rectum.
The present invention's large domestic animal Ultrasonography coupling lubricant is applicable to examination per rectum and uses, and is particularly suitable for the large domestic animal Ultrasonography such as donkey, horse, cattle and uses.
Accompanying drawing explanation
Below in conjunction with accompanying drawing to the common couplant of use and coupling lubricant of the present invention, examination per rectum gained B ultrasonic image is carried out to donkey and contrasts:
Fig. 1 uses common couplant to carry out examination per rectum gained B ultrasonic image for donkey;
Fig. 2 is the present embodiment 1 gained coupling lubricant is that donkey carries out examination per rectum gained B ultrasonic image;
Fig. 3 is the present embodiment 2 gained coupling lubricant is that donkey carries out examination per rectum gained B ultrasonic image;
Fig. 4 is the present embodiment 3 gained coupling lubricant is that donkey carries out examination per rectum gained B ultrasonic image.
Detailed description of the invention
Embodiment 1:(1) the card ripple of getting 3 grams adds in the deionized water of 300 grams, and heating in water bath Keep agitation 20min, is cooled to room temperature, obtains A liquid;
(2) three Sodium ethylate getting 3 grams are dissolved in A liquid mix homogeneously, obtain B liquid;
(3) get the sodium lauryl sulphate of 150 grams and the sodium citrate of 3 grams adds in the deionized water of 400 grams, be heated to 75 DEG C, after dissolving, be cooled to room temperature, obtain C liquid;
(4) povidone iodine getting 50 grams is dissolved in mix homogeneously in C liquid, obtains D liquid;
(5) cocoanut fatty acid diethanolamide getting 40 grams is incorporated in D liquid, and mix homogeneously obtains E liquid;
(6) sodium hydroxyethlcellulose getting 40 grams adds in E liquid, be uniformly mixed, obtain F liquid, then add (2) gained B liquid, be uniformly mixed, obtain the present invention's large domestic animal Ultrasonography coupling lubricant (I) 989 gram.
Use commercially available common Ultrasonography couplant, it is unclear that gained is image blurring.As shown in Figure of description 1, meanwhile, need, with 30 grams of couplants, the hands of Ultrasonic-B probe and operator to be filled.
Large domestic animal Ultrasonography coupling lubricant (I) of the above-mentioned invention prepared is used to detect for donkey rectum, gained B ultrasonic clear picture, clear, as shown in Figure of description 2.
Meanwhile, use this large domestic animal Ultrasonography coupling lubricant (I), only need 15 grams, just the hands of Ultrasonic-B probe and operator can be filled.Such one side couplant consumption is few, and cost is low, and cleaning, sterilization are convenient.
Embodiment 2:(1) the card ripple of getting 6 grams adds in the deionized water of 300 grams, and heating in water bath Keep agitation 20min, is cooled to room temperature, obtains A liquid;
(2) three Sodium ethylate getting 1 gram are dissolved in A liquid mix homogeneously, obtain B liquid;
(3) get the sodium lauryl sulphate of 125 grams and the sodium citrate of 6 grams adds in the deionized water of 350 grams, be heated to 70 DEG C, after dissolving, be cooled to room temperature, obtain C liquid;
(4) povidone iodine getting 40 grams is dissolved in mix homogeneously in C liquid, obtains D liquid;
(5) cocoanut fatty acid diethanolamide getting 20 grams is incorporated in D liquid, and mix homogeneously obtains E liquid;
(6) sodium hydroxyethlcellulose getting 70 grams adds in E liquid and is uniformly mixed, obtain F liquid, then add (2) gained B liquid, be uniformly mixed, obtain the present invention's large domestic animal Ultrasonography coupling lubricant (II) 918 gram.
Use large domestic animal Ultrasonography coupling lubricant (II) of the above-mentioned invention prepared to detect for donkey rectum, gained B ultrasonic image is also very clear, as shown in Figure of description 3.
Embodiment 3:(1) the card ripple of getting 4 grams adds in the deionized water of 300 grams, and heating in water bath Keep agitation 20min, is cooled to room temperature, obtains A liquid;
(2) three Sodium ethylate getting 5 grams are dissolved in A liquid mix homogeneously, obtain B liquid;
(3) get the sodium lauryl sulphate of 100 grams and the sodium citrate of 5 grams adds in the deionized water of 450 grams, be heated to 80 DEG C, after dissolving, be cooled to room temperature, obtain C liquid;
(4) povidone iodine getting 30 grams is dissolved in mix homogeneously in C liquid, obtains D liquid;
(5) cocoanut fatty acid diethanolamide getting 30 grams is incorporated in D liquid, and mix homogeneously obtains E liquid;
(6) sodium hydroxyethlcellulose getting 55 grams adds in E liquid and is uniformly mixed, obtain F liquid, then add (2) gained B liquid, be uniformly mixed, obtain the present invention's large domestic animal Ultrasonography coupling lubricant (III) 979 gram.
Use large domestic animal Ultrasonography coupling lubricant (III) of the above-mentioned invention prepared to detect for donkey rectum, gained B ultrasonic image is also very clear, as shown in Figure of description 3.
Note: above-described embodiment is all matching while using, institute joins large domestic animal Ultrasonography coupling lubricant and was all finished in four hours.More than four hours, gained B ultrasonic picture specification book accompanying drawing 1 was compared, and definition advantage declines to some extent, slightly.
Prepare B liquid and F liquid respectively in proportion in advance, and preserve shady and cool place respectively, claim in proportion before use to get B liquid and F liquid respectively, mix homogeneously, and be finished in four hours, result of use is identical with now with the current, slightly.
Claims (4)
1. a large domestic animal Ultrasonography coupling lubricant, by the card ripple of 0.3 ~ 0.6 weight portion; Three Sodium ethylate of 0.1 ~ 0.5 weight portion; The sodium lauryl sulphate of 10 ~ 15 weight portions; The sodium citrate of 0.3 ~ 0.6 weight portion; The povidone iodine of 3 ~ 5 weight portions; The cocoanut fatty acid diethanolamide of 2 ~ 4 weight portions; The carboxyethyl cellulose of 4-7 weight portion is received and the deionized water of 65 ~ 75 weight portions is made.
2. a preparation method for large domestic animal Ultrasonography coupling lubricant, comprises the following steps:
(1) the card ripple getting 0.3 ~ 0.6 weight portion adds in the deionized water of 30 weight portions, and heating in water bath Keep agitation 20min, is cooled to room temperature, obtains A liquid;
(2) three Sodium ethylate getting 0.1 ~ 0.5 weight portion are dissolved in A liquid mix homogeneously, obtain B liquid;
(3) sodium citrate of the sodium lauryl sulphate and 0.3 ~ 0.6 weight portion of getting 10 ~ 15 weight portions adds in the deionized water of 35 ~ 45 weight portions, is heated to 70 ~ 80 DEG C, is cooled to room temperature after dissolving, obtain C liquid;
(4) povidone iodine getting 3 ~ 5 weight portions is dissolved in mix homogeneously in C liquid, obtains D liquid;
(5) cocoanut fatty acid diethanolamide getting 2 ~ 4 weight portions is incorporated in D liquid, and mix homogeneously obtains E liquid;
(6) sodium hydroxyethlcellulose getting 4-7 weight portion adds in E liquid, and stirring and evenly mixing, obtains F liquid, then adds (2) gained B liquid, stirring and evenly mixing, obtains product of the present invention.
3. a using method for large domestic animal Ultrasonography coupling lubricant, is characterized in that: prepare large domestic animal Ultrasonography coupling lubricant described in claim 2 before use, and be finished in four hours.
4. a using method for large domestic animal Ultrasonography coupling lubricant, is characterized in that: first prepare B liquid and F liquid respectively in proportion, and preserves shady and cool place respectively, before use by B liquid and F liquid, and mix homogeneously, and be finished in four hours.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510643929.0A CN105106980B (en) | 2015-09-30 | 2015-09-30 | Big domestic animal Ultrasonography coupling lubricant and preparation method and application method |
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| CN201510643929.0A CN105106980B (en) | 2015-09-30 | 2015-09-30 | Big domestic animal Ultrasonography coupling lubricant and preparation method and application method |
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| CN105106980B CN105106980B (en) | 2018-07-31 |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4886068A (en) * | 1985-07-29 | 1989-12-12 | Kabushiki Kaisha Toshiba | Ultrasonic coupling agent |
| CN1374133A (en) * | 2002-03-21 | 2002-10-16 | 黎国梓 | B-mode ultrasound coupling agent and its prepn |
| CN101920023A (en) * | 2010-04-24 | 2010-12-22 | 王勇 | Transrectal ultrasound medical coupling agent |
| CN104667304A (en) * | 2015-01-08 | 2015-06-03 | 青岛明药堂医疗股份有限公司 | Ultrasonic coupling agent and preparation method thereof |
-
2015
- 2015-09-30 CN CN201510643929.0A patent/CN105106980B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4886068A (en) * | 1985-07-29 | 1989-12-12 | Kabushiki Kaisha Toshiba | Ultrasonic coupling agent |
| CN1374133A (en) * | 2002-03-21 | 2002-10-16 | 黎国梓 | B-mode ultrasound coupling agent and its prepn |
| CN101920023A (en) * | 2010-04-24 | 2010-12-22 | 王勇 | Transrectal ultrasound medical coupling agent |
| CN104667304A (en) * | 2015-01-08 | 2015-06-03 | 青岛明药堂医疗股份有限公司 | Ultrasonic coupling agent and preparation method thereof |
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| CN105106980B (en) | 2018-07-31 |
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