CN105105785A - Method, device and equipment for automatically removing ultrasound contrast imaging non-contrast region - Google Patents

Abstract

The invention provides a method for automatically removing an ultrasound contrast imaging non-contrast region. The method comprises the following steps: collecting N rolls of ultrasound contrast imaging data in a filling process of a contrast agent, wherein N is greater than or equal to 2; setting a grey value difference threshold T of two adjacent rolls of ultrasound contrast imaging data; solving a grey value difference between every two adjacent rolls of ultrasound contrast imaging data at all the same positions in the N rolls of ultrasound contrast imaging data; comparing the solved grey value difference with the threshold T, setting a point where the grey value difference is greater than the threshold T as a contrast imaging region, estimating a background region by solving a complementary set of N rolls of contrast imaging region union sets, and removing the background region. The invention also provides a corresponding device and corresponding equipment. By the adoption of the method, the device and the equipment, the background region is estimated according to the grey value difference between every two adjacent rolls of data at the same positions in the filling process of the contrast agent and is removed for each roll of data of an ultrasound image, so that the operation trouble of manually removing the background region by a doctor in ultrasound contrast imaging is eliminated.

Description

Ultrasonic contrast imaging non-radiography region automatic removal method, device and equipment

Technical field

The present invention relates to ultrasonic imaging technique field, be specifically related to ultrasonic contrast imaging non-radiography region automatic removal method, device and equipment.

Background technology

Hysterosalpingocontrast sonography four-dimensional imaging, it is the volume probe using motor to drive, gather multireel (volume) radiography volume data, the mode of the flowing of contrast agent in uterus, fallopian tube, pelvic cavity, disperse process stereoscopic three-dimensional film (four-dimension) is presented.Doctor is according in this process: the nowed forming of contrast agent, contrast agent the form that fimbriated extremity of fallopian overflows and contrast agent from fimbriated extremity of fallopian out time, the situations such as the form of disperse in pelvic cavity, diagnose the physiological situation of patient.

Due to impacts such as ultrasonic image noise, artifact and tissue echo signal, contrast agent perfusion area image can not be observed well, after basin baselap sound four-dimensional imaging is published picture, doctor needs manually to use 4D data clipping function usually, extraneous areas (background) is removed.This needs to operate frame by frame 4D film, very time-consuming.

Summary of the invention

For solving the problem, the present invention proposes a kind of ultrasonic contrast imaging non-radiography region automatic removal method, device and equipment.According to identical gray value differences estimated background region of adopting the adjacent two volume data of figure position in perfusion contrast agent process, background area is removed to each volume data of ultrasonoscopy, to reach the object automatically removing non-contrast perfusion region in contrast imaging, thus remove from ultrasonic contrast imaging, doctor manually removes the trouble of background area operation, is therefore more conducive to the disperse situation of observing contrast agent.

The invention provides a kind of ultrasonic contrast imaging non-radiography region automatic removal method, described method comprises:

A kind of ultrasonic contrast imaging non-radiography region automatic removal method, it is characterized in that, described method comprises:

The N gathered in perfusion contrast agent process rolls up ultrasonic contrast imaging data, N >=2;

The threshold value T of the gray value differences of the ultrasonic contrast imaging data of adjacent two volumes is set;

Described N is asked to roll up the gray value differences of the ultrasonic contrast imaging data of all same positions of adjacent two volume in ultrasonic contrast imaging data;

The described gray value differences asked compared with described threshold value T-phase, the point described gray value differences being greater than described threshold value T is set to contrast imaging region;

Remove non-contrast imaging region.

The present invention also provides a kind of ultrasonic contrast imaging device that non-radiography region is removed automatically, and described device comprises:

The device that the non-radiography region of ultrasonic contrast imaging is removed automatically, described device comprises:

Collecting unit, rolls up ultrasonic contrast imaging data for the N gathered in perfusion contrast agent process.

First computing unit, for the threshold value T of the gray value differences of the ultrasonic contrast imaging data of adjacent two volumes;

Second computing unit, for the gray value differences asking described N to roll up the ultrasonic contrast imaging data of all same positions of adjacent two volume in ultrasonic contrast imaging data;

3rd computing unit, for the described gray value differences asked being compared with described threshold value T-phase, the point described gray value differences being greater than described threshold value T is set to contrast imaging region, then remainder is non-contrast imaging region;

Control unit, for removing non-contrast imaging region.

The present invention also provides a kind of equipment, and described equipment comprises device as above.

As can be seen from the above technical solutions, the embodiment of the present invention has the following advantages:

Owing to estimating foreground area according to gray value differences of adopting the adjacent two volume data of figure position identical in perfusion contrast agent process, background area is removed to each volume data of ultrasonoscopy, to reach the object automatically removing non-contrast perfusion region in contrast imaging, thus remove from ultrasonic contrast imaging, doctor manually removes the trouble of background area operation, is therefore more conducive to the disperse situation of observing contrast agent.

Accompanying drawing explanation

Fig. 1 is the overall flow schematic diagram of the ultrasonic contrast four-dimensional imaging non-radiography region automatic removal method of an embodiment of the present invention;

Fig. 2 is the overall flow schematic diagram of the ultrasonic contrast four-dimensional imaging non-radiography region automatic removal method of the another kind of embodiment of the present invention;

Fig. 3 is the part run schematic diagram of the ultrasonic contrast four-dimensional imaging non-radiography region automatic removal method of the another kind of embodiment of the present invention;

Fig. 4 is the overall structure block diagram of the automatic removal device in ultrasonic contrast four-dimensional imaging non-radiography region of the another kind of embodiment of the present invention;

Fig. 5 is the overall structure block diagram of the automatic removal device in ultrasonic contrast four-dimensional imaging non-radiography region of the another kind of embodiment of the present invention;

Fig. 6 is the structured flowchart of the 3rd computing unit of the automatic removal device in ultrasonic contrast four-dimensional imaging non-radiography region of the another kind of embodiment of the present invention.

Detailed description of the invention

The present invention proposes a kind of ultrasonic contrast imaging non-radiography region automatic removal method, device and equipment.Foreground area is estimated according to gray value differences of adopting the adjacent two volume contrast imaging data of figure position identical in perfusion contrast agent process, background area is removed to each volume data of ultrasonoscopy, to reach the object automatically removing non-contrast perfusion region in contrast imaging, thus remove from ultrasonic contrast imaging, doctor manually removes the trouble of background area operation, is therefore more conducive to the disperse situation of observing contrast agent.

Below in conjunction with the Figure of description in the present invention, be clearly and completely described the technical scheme in invention, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.

It should be noted that, the present invention is applicable to the automatic removal in the non-radiography region of the various ultrasonic contrast such as two dimension, four-dimension image.

Embodiment one,

As shown in Figure 1, be a kind of ultrasonic contrast imaging non-radiography region automatic removal method described in the specific embodiment of the invention, specifically comprise the steps:

S101, the N gathered in perfusion contrast agent process roll up ultrasonic contrast imaging data.

By the ultrasonic contrast imaging data in the contrast agent perfusion process of probe acquires same position.

Probe Ultrasonic Searching transducer launches ultrasonic signal to destination organization, and receives echo-signal.Echo-signal is converted to analog electrical signal, finally by A/D conversion chip, analog electrical signal is converted to digital signal.Here digital signal is ultrasonic contrast imaging data.

Pop one's head in every scanning once, obtains volume ultrasonic contrast data, in contrast agent perfusion process, continuous scanning of popping one's head in, obtains N at same position and rolls up ultrasonic contrast imaging data (N is the integer of >=2).

S102, arranges the threshold value T of the gray value differences of the ultrasonic contrast imaging data of adjacent two volumes.

The method to set up of described threshold value T can comprise: the gray value mean square deviation, intensity histogram map analysis etc. of averaging method, two volume data.

S103, asks described N to roll up the gray value differences of the ultrasonic contrast imaging data of all same positions of adjacent two volume in ultrasonic contrast imaging data.

1. suppose that N rolls up data with 1,2,3.。。, N numbers;

2. get and be numbered 1, the data of 2 volumes, the average gray obtaining them is poor, and this gray scale difference is set to present threshold value T;

3. subtracted each other the gray value of numbering 1,2 volume identical point coordinate, what be greater than threshold value T is set to effective coverage, i.e. radiography region.If the coordinate point set of current record is S1;

4. choose again and be numbered 2, the data of 3, repeat 2-3 step, here it is to be noted that step 2 also will repeat, so each threshold value is different, if the coordinate point set of current record is S2;

5. constantly repeat 2-4 step, be traversed until N rolls up data.Now have recorded N-1 point set altogether;

6. this N-1 point set is got union, union is now radiography region; The supplementary set of union is background area.

7. what gray value differences was greater than threshold value must be radiography region, because the region of contrast agent flow warp has strong reflection; But gray value differences is less than the not necessarily background area of threshold value, and is likely that contrast agent does not flow to.So just want every two volume data to judge, travel through N volume always.

S104, compares the described all gray value differences asked for threshold value T-phase; Point gray value differences being greater than threshold value T is set to contrast imaging region.

Another order chooses adjacent two volume ultrasonic contrast data, repeats S102, S103, S104 step and asks for contrast imaging region, chooses until described N volume ultrasonic contrast imaging data are traversed.

S105, removes non-contrast imaging region.

According to the contrast imaging region (i.e. foreground area) that S104 calculates, and remaining part is background area, rolls away except background area each of ultrasound imaging data.So far radiography region is only left in ultrasonoscopy.

In sum, according to identical gray value differences estimated background region of adopting the adjacent two volume data of figure position in perfusion contrast agent process, background area is removed to each volume data of ultrasonoscopy, to reach the object automatically removing non-contrast perfusion region in contrast imaging, thus remove from ultrasonic contrast imaging, doctor manually removes the trouble of background area operation, is therefore more conducive to the disperse situation of observing contrast agent.

Further, as shown in Figure 2, described the threshold value T of the gray value differences of the ultrasonic contrast imaging data of adjacent two volumes of same position is set before also comprise the method for noise reduction process carried out to the ultrasound data gathered.

The benefit of carrying out noise reduction process is: contribute to the speckle noise reducing ultrasonic contrast image, avoid the erroneous judgement in later stage contrast agent perfusion region.

The method of described noise reduction process can comprise: gaussian filtering, anisotropic filtering, mean filter, bilateral filtering etc.Described each side is owned by France in prior art, does not repeat them here.

Further, as shown in Figure 3, the described all gray value differences asked for compare with threshold value T-phase by described step S104; Point gray value differences being greater than threshold value T is set to contrast imaging region, comprises the steps:

S1041, compares the described gray value differences asked for described threshold value T-phase, if be greater than gray value differences threshold value T, using this point as available point record.

By rear volume contrast imaging data, deduct the gray value of last volume contrast imaging data correspondence position point, if be greater than threshold value T, then the location records of this point is got off.Remember that the point set that current volume contrast imaging data go on record is ValidRegion _i,

ValidRegion _i＝{point _curVol(i，j，k)∈Vol _cur|(point _curVol(i，j，k)-point _preVol(i，j，k))＞T}

Point _curVol(i, j, k) point that to be a rear volume coordinate in two volume data be (i, j, k); Point _preVol(i, j, k) is that in two volume data, last volume coordinate is the point of (i, j, k), ValidRegion _ifor the contrast agent perfusion region point set judged according to method above;

S1042, the N gathered described in order traversal roll up contrast imaging data, and often adjacent two volumes obtain a point set ValidRegion _i, the to the last efficient point set ValidRegion of a volume _n-1asked for out.

S1043, is set to non-radiography region by the supplementary set of described available point union.

If the point set that the 2nd volume is recorded is ValidRegion ₁, the 3rd volume is ValidRegion ₂..., the point set that the n-th volume is recorded is ValidRegion _n-1.Background dot region is set to:

$BK\mathrm{Re}gion=\{po\mathrm{int}(i,j,k)\∈\stackrel{\‾}{{\mathrm{ValidRegion}}_1\∪{\mathrm{ValidRegion}}_2\∪\mathrm{...}\∪{\mathrm{ValidRegion}}_{n-1}}\}$

Point (i, j, k) point (i, j, k) for gathered ultrasound image coordinates be the point of (i, j, k); ValidRegionValidRegion is the contrast agent perfusion region point set judged according to method above; BKRegionBKRegion is background area point set.

Namely non-radiography region is the supplementary set of effective coverage union;

Further, the described method arranging gray value differences threshold value T comprises, average gray value difference in statistics contrast agent perfusion process between the adjacent two volume ultrasonic contrast data of same position each point, using this gray value differences as threshold value T, described average gray difference acquiring method can adopt following two formula to ask for:

$T=\frac{|\underset{i=1}{\overset{frms}{\Σ}}\underset{j=1}{\overset{rows}{\Σ}}\underset{k=1}{\overset{cols}{\Σ}}{V}_1(i,j,k)-\underset{l=1}{\overset{frms}{\Σ}}\underset{m=1}{\overset{rows}{\Σ}}\underset{n=1}{\overset{cols}{\Σ}}{V}_2(l,m,n)|}{frms\·rows\·cols}.$

$T=\frac{\underset{i=1}{\overset{frms}{\Σ}}\underset{j=1}{\overset{rows}{\Σ}}\underset{k=1}{\overset{cols}{\Σ}}|V_1(i,j,k)-V_2(l,m,n)|}{frms\·rows\·cols}$ (method 2)

Wherein, V ₁(i, j, k) for the last volume coordinate in adjacent two volume data be the gray value that (i, j, k) puts; V ₂(i, j, k) for the rear volume data coordinates in adjacent two volume data be the gray value that (i, j, k) puts.Frms is the totalframes in volume data, and rows is the line number of frame data in volume data; Cols is the columns of frame data in volume data.T is required threshold value, and M is the average gray value of adjacent two volume data.

Embodiment two,

As shown in Figure 4, the specific embodiment of the invention also provides a kind of ultrasonic contrast imaging device 300 that non-radiography region is removed automatically.Described device comprises:

Collecting unit 301, rolls up ultrasonic contrast imaging data for the N gathered in perfusion contrast agent process.

First computing unit 302, for the threshold value T of the gray value differences of the ultrasonic contrast imaging data of adjacent two volumes;

Second computing unit 303, for the gray value differences asking described N to roll up the ultrasonic contrast imaging data of all same positions of adjacent two volume in ultrasonic contrast imaging data;

3rd computing unit 304, for the described gray value differences asked being compared with described threshold value T-phase, the point described gray value differences being greater than described threshold value T is set to contrast imaging region, then remainder is non-contrast imaging region;

Control unit 305, for removing non-contrast imaging region.

Further, as shown in Figure 5, described device 400 also comprises the 4th and calculates Unit 406, for carrying out noise reduction process to the ultrasound data gathered.

Further, as shown in Figure 6, described 3rd computing unit 304 comprises: the first accountant 3041, second accountant 3042, the 3rd accountant 3043.

Described first accountant, for the described gray value differences asked being compared with described threshold value T-phase, is greater than the point of described threshold value T as radiography region point record using described gray value differences;

Described second accountant, roll up contrast imaging data for the N gathered described in order traversal, often adjacent two volumes obtain a point set, and to the last the efficient point set of a volume is asked for out;

Described 3rd accountant, for being set to background dot region by the supplementary set of described available point union.

The work process of described each device, see embodiment one, does not repeat them here.

Embodiment three,

For a kind of equipment described in the embodiment of the present invention, described equipment is ultrasonic device, and described ultrasonic device comprises the device as described in any embodiment two, and described device, see specific embodiment two, does not repeat them here.

Above the non-radiography region of a kind of ultrasonic contrast imaging provided by the present invention automatic removal method, device and equipment are described in detail, for one of ordinary skill in the art, according to the thought of the embodiment of the present invention, all will change in specific embodiments and applications, therefore, this description should not be construed as limitation of the present invention.

Claims (8)

1. a ultrasonic contrast imaging non-radiography region automatic removal method, is characterized in that, described method comprises:

The N gathered in perfusion contrast agent process rolls up ultrasonic contrast imaging data, N >=2;

The threshold value T of the gray value differences of the ultrasonic contrast imaging data of adjacent two volumes is set;

Described N is asked to roll up the gray value differences of the ultrasonic contrast imaging data of all same positions of adjacent two volume in ultrasonic contrast imaging data;

The described gray value differences asked compared with described threshold value T-phase, the point described gray value differences being greater than described threshold value T is set to contrast imaging region, then remainder is non-contrast imaging region;

Remove non-contrast imaging region.

2. method according to claim 1, is characterized in that, described the gray value differences threshold value T of the ultrasonic contrast imaging data of adjacent two volumes is set before also comprise, noise reduction process is carried out to the ultrasonic contrast imaging data of described collection.

3. method according to claim 1 and 2, it is characterized in that, describedly the described gray value differences asked for compared with described threshold value T-phase, the point described gray value differences being greater than described threshold value T is set to contrast imaging region, then remainder is that non-contrast imaging region comprises:

The described gray value differences asked for is compared with described threshold value T-phase, described gray value differences is greater than the point of described threshold value T as radiography region point record;

The N gathered described in order traversal rolls up contrast imaging data, and often adjacent two volumes obtain a point set, and to the last the efficient point set of a volume is asked for out;

The supplementary set of described available point union is set to non-contrast imaging region.

4. method according to claim 1 and 2, it is characterized in that, the described method arranging gray value differences threshold value T comprises, average gray value difference in statistics contrast agent perfusion process between identical adjacent two volume ultrasonic contrast imaging data of adopting figure position, using described average gray value difference as present threshold value T.

5. the device automatically removed of the non-radiography region of ultrasonic contrast imaging, described device comprises:

Collecting unit, rolls up ultrasonic contrast imaging data for the N gathered in perfusion contrast agent process.

First computing unit, for the threshold value T of the gray value differences of the ultrasonic contrast imaging data of adjacent two volumes;

Second computing unit, for the gray value differences asking described N to roll up the ultrasonic contrast imaging data of all same positions of adjacent two volume in ultrasonic contrast imaging data;

3rd computing unit, for the described gray value differences asked being compared with described threshold value T-phase, the point described gray value differences being greater than described threshold value T is set to contrast imaging region, then remainder is non-contrast imaging region;

Control unit, for removing non-contrast imaging region.

6. device according to claim 5, is characterized in that, described device also comprises the 4th computing unit, for carrying out noise reduction process to the ultrasonic contrast imaging data of described collection.

7. the device according to claim 5 or 6, is characterized in that, described 3rd computing unit comprises: the first accountant, the second accountant; 3rd accountant

Described first accountant, compares the described gray value differences asked for described threshold value T-phase, and described gray value differences is greater than the point of described threshold value T as radiography region point record;

Described second accountant, roll up contrast imaging data for the N gathered described in order traversal, often adjacent two volumes obtain a point set, and to the last the efficient point set of a volume is asked for out;

Described 3rd accountant, for being set to background dot region by the supplementary set of described available point union.

8. an equipment, is characterized in that, described equipment comprises the device as described in claim 5-7 any one.