CN105012059B - Biodegradable drug stent - Google Patents

Biodegradable drug stent Download PDF

Info

Publication number
CN105012059B
CN105012059B CN201410410095.4A CN201410410095A CN105012059B CN 105012059 B CN105012059 B CN 105012059B CN 201410410095 A CN201410410095 A CN 201410410095A CN 105012059 B CN105012059 B CN 105012059B
Authority
CN
China
Prior art keywords
annulus
crest
rhombus
biodegradable drug
drug stent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201410410095.4A
Other languages
Chinese (zh)
Other versions
CN105012059A (en
Inventor
吴天根
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DONGGUAN TIANTIANXIANGSHANG MEDICAL TECHNOLOGY CO Ltd
Original Assignee
DONGGUAN TIANTIANXIANGSHANG MEDICAL TECHNOLOGY CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DONGGUAN TIANTIANXIANGSHANG MEDICAL TECHNOLOGY CO Ltd filed Critical DONGGUAN TIANTIANXIANGSHANG MEDICAL TECHNOLOGY CO Ltd
Priority to CN201410410095.4A priority Critical patent/CN105012059B/en
Priority to PCT/CN2014/092641 priority patent/WO2016026235A1/en
Publication of CN105012059A publication Critical patent/CN105012059A/en
Application granted granted Critical
Publication of CN105012059B publication Critical patent/CN105012059B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58Materials at least partially resorbable by the body

Abstract

The invention discloses a biodegradable drug stent. The stent is tubular and comprises a plurality of first circular rings which are arranged longitudinally, each first circular ring is in the sinusoidal waveform in the circumferential direction, and the plurality of first circular rings are aligned longitudinally; a second circular ring is arranged between every two longitudinally adjacent first circular rings, each second circular ring is formed by connecting a plurality of rhombuses in a surrounding mode in the circumferential direction, and two connecting arms are connected between the wave crests, close to the second circular ring longitudinally, of the two first circular rings and the second circular ring respectively, so that the two first circular rings, the second circular ring and the plurality of connecting arms form a plurality of honeycomb structures and a plurality of diamond-shaped structures; each honeycomb structure comprises two diamond-shaped structures; after the stent is expanded, the plurality of honeycomb structures and diamond-shaped structures are linked mutually to form a stable supporting structure, so that the radial supporting force of the stent is strengthened.

Description

A kind of biodegradable drug stent
Technical field
The present invention relates to technology inserted by support, more particularly, to a kind of biodegradable drug stent.
Background technology
Clinically, the basic demand to human body official jargon implantation instrument includes:After apparatus implanted human body official jargon organ, not only It is provided that the enough mechanical support power of implanted organ, slowly can discharge medicine wall of the lumen in organism by continuous uniform again Interior, with effective control by implanting the foreign body reaction that prosthese is led to.
Medicament-release blood vessel stent is exactly a kind of implantation prosthese meeting above standard.Support is plain cylindrical form device, Tube chamber can be kept unobstructed, sometimes can be with expansion of blood vessels or other dissection tube chamber such as ureters, bile duct.Support is frequently used for blood The official jargon stenosis disease that pipe atherosclerosiss lead to.Luminal stenosis refer to that internal tube chamber narrows or tightens.At this In the middle for the treatment of meanss, support plays a supportive role in tube chamber in case vascular restenosiss occur after the Tuboplasty that stops blooding.Restenosiss are Refer to vessel lumen or cardiac valve after carrying out the successful treatment such as balloon expandable, stenter to implant, valvoplasty again Occur is narrow.
Support can be made of a variety of materials, including metal and polymeric material.In polymer support, biodegradable The many advantages of polymer support tool:First, after biodegradable stent implantation official jargon, after completing the expansion support to narrow official jargon, Can be by body automatic absorption, thus after avoiding by the advanced thrombus leading in non-degradable support prolonged stay body and restenosiss Lose disease.Secondly, can be equipped with the medicine of suppression vascular restenosiss in degradable polymer body, after stenter to implant, medicine is with support Degrade and slowly discharge, thus the mode of permanently effective control vascular restenosiss.In conventional metals drug stent, medicine is only The surface of metal rack can be sprayed at, and discharge in 28 days after stenter to implant and finish.
But the subject matter that current polymeric material support exists be support support force low it is impossible to fully meet clinical crown Cardiopathia disease human needs.For solving this problem, before the applicant, apply for that Chinese Patent Application No. is 201280036466.6 patent of invention, it is disclosed that a kind of particular design of biodegradable drug stent, this support is in Tubulose, including multiple the first annulus along longitudinal arrangement, this first annulus is in sinusoidal wave form in circumferencial direction, and multiple first circle Ring is along longitudinally-aligned;Wherein, by the company of S-shaped between two adjacent longitudinal corresponding crests close to each other in the first annulus edge Connect arm to connect, make two the first annulus and the linking arm of a plurality of S-shaped form multiple honeycomb shaped structure;Set between two the first annulus It is equipped with the second annulus, this second annulus is in also sinusoidal wave form in circumferencial direction, makes the ground that the linking arm of the second annulus and S-shaped intersects Square one-tenth X-shaped structure.
Wherein, this biodegradable drug stent is disadvantageous in that:The linking arm of two S-shaped of honeycomb shaped structure Between, only there is an attachment structure of the second annulus, therefore in the case of expansion, support may not provide enough footpaths To support force, so still needing to improve its structure.
Content of the invention
Present invention aims to the deficiencies in the prior art and a kind of biodegradable drug stent is provided, it passes through Strengthening the stability after honeycomb shaped structure expansion, thus strengthening the radial support power of support, solving the above problems.
To achieve these goals, the present invention employs the following technical solutions:
A kind of biodegradable drug stent, in a tubular form, including multiple the first annulus along longitudinal arrangement, this for this support One annulus is in sinusoidal wave form in circumferencial direction, and multiple first annulus is along longitudinally-aligned;Two along the first longitudinally adjacent annulus Between be provided with the second annulus, this second annulus in circumferencial direction by multiple rhombuses around connecting and composing, and two first circles Ring along being longitudinally respectively connected with a linking arm between the crest and the second annulus of this second annulus, make two the first annulus with Second annulus and a plurality of linking arm form multiple honeycomb shaped structure and multiple diamond structure, and each honeycomb shaped structure includes two Individual diamond structure, this two diamond structures are symmetrical arranged with the cross central line of honeycomb shaped structure.
Wherein, linking arm one end is connected with the crest of the first annulus, the crest pair of the linking arm other end and this first annulus The midpoint on the side of the rhombus of the second annulus answered connects, and makes the crest of four the first annulus and a rhombus and four of the second annulus Bar linking arm forms a honeycomb shaped structure, and the one of two sides of a rhombus of the crest of two the first annulus and the second annulus Half and two linking arms form diamond structures.
Wherein, the horizontal catercorner length of the rhombus of the second annulus be equal to the first annulus two sine wave wavelength, second Longitudinal catercorner length of the rhombus of annulus is less than the longitudinal pitch of two first annulus.
Wherein, linking arm one end is connected with the crest of the first annulus, the crest pair of the linking arm other end and this first annulus Longitudinal summit of the rhombus of the second annulus answered connects, and makes the crest of four the first annulus and two rhombuses of second annulus Connect the X-shaped structure being formed and four linking arms form a honeycomb shaped structure, and the crest of two the first annulus and the second circle One side of two rhombuses of ring and two linking arms form a diamond structure.
Wherein, the horizontal catercorner length of the rhombus of the second annulus be equal to the first annulus a sine wave wavelength, second Longitudinal catercorner length of the rhombus of annulus is less than the longitudinal pitch of two first annulus.
Wherein, this honeycomb shaped structure a pair of linking arm along the circumferential direction is in bracket shape.
Wherein, the first annulus is made up of the ripple of multiple V-arrangements, and the ripple of this V-arrangement has crest and is located at this crest both sides Swing wall.
Wherein, this support is made up of polylactic acid.
Wherein, this support at least has an additional or embedded identification labelling.
Wherein, this identification is labeled as roentgenopaque pointing object or tablet.
The present invention has the beneficial effects that:The present invention first annulus and the second annulus and a plurality of linking arm form multiple honeycombs Structure and multiple diamond structure, and each honeycomb shaped structure includes two diamond structures, after stent-expansion, multiple honeycombs Structure and the interactive link of diamond structure, form a firm supporting construction, thus strengthening the radial support power of support.
Brief description
Patent application document comprises at least one color execution picture.If official demands and provide necessary expenses pay Money can provide this patent or the copy of Patent Application Publication coloured picture picture.
Fig. 1 is the panorama sketch of the support of the embodiment of the present invention 1 of the automatic Microcomputer Drawing Software on Drawing of two dimension.
Fig. 2 is that the plane of first annulus of the support of the embodiment of the present invention 1 of the automatic Microcomputer Drawing Software on Drawing of two dimension regards Figure.
Fig. 3 is two dimension second annulus of the support of the embodiment of the present invention 1 of Microcomputer Drawing Software on Drawing and linking arm automatically Plan view.
Fig. 4 is the plane of the honeycomb shaped structure of the support of the embodiment of the present invention 1 of the automatic Microcomputer Drawing Software on Drawing of two dimension View.
Fig. 5 is the axonometric chart after the stent-expansion of the embodiment of the present invention 1 that computer analog illustration is described.
Fig. 6 is the photo on dilating sacculus for the support of the embodiment of the present invention 1.
Fig. 7 is the X-ray image figure after 6 months for the stenter to implant pig arteria coronaria of the embodiment of the present invention 1.
Fig. 8 is the ivus image display figure after 6 months for the stenter to implant Sanguis sus domestica pipe of the embodiment of the present invention 1.
Fig. 9 is the pathological staining picture after 6 months for the stenter to implant pig arteria coronaria of the embodiment of the present invention 1.
Figure 10 is the axonometric chart after the stent-expansion of the embodiment of the present invention 2 that computer analog illustration is described.
Specific embodiment
In order to describe technical scheme in detail, below in conjunction with the accompanying drawing of the embodiment of the present invention, real to the present invention The technical scheme applying example carries out clear, complete description.Obviously, described embodiment is a part of embodiment of the present invention, Rather than whole embodiments.Based on described embodiments of the invention, those of ordinary skill in the art are need not be creative The every other embodiment being obtained on the premise of work, broadly falls into the scope of protection of the invention.
Embodiment 1
In one embodiment, the Biodegradable scaffold of the present invention has radial support power and the geometrical stability of increase Property.Fig. 1~6 depict the pattern of an embodiment medium-height trestle 100.Support 100 in a tubular form, especially after support 100 expansion, is such as schemed Shown in 5 and Fig. 6, support 100 is made to implant sustainable blood vessel after expansion.
In Fig. 1~4, support 100 is with plan representation, so that the view of support can clearly present.
Support 100 includes multiple the first annulus 101 along longitudinal arrangement, and the first annulus 101 is in sine wave in circumferencial direction Shape, and multiple first annulus 101 is along longitudinally-aligned.As shown in Figure 2 it is preferred that the first annulus 101 by multiple V-arrangements ripple 10 Constitute, that is, multiple transversely arranged V-arrangement ripples 10 are constituted, the ripple 10 of V-arrangement has crest 11 and the pendulum positioned at crest 11 both sides Dynamic wall 12.
Two are provided with the second annulus 102 along between the first longitudinally adjacent annulus 101, and the second annulus 102 is in circumference side Connect and compose to by the cincture of multiple rhombuses.And two the first annulus 101 along longitudinally near the second annulus 102 crest (as Fig. 1 The crest 11 of middle mark) and the second annulus 102 between, be respectively connected with a linking arm 13, i.e. each crest of the first annulus 101 All it is connected with the second annulus 102 by a corresponding linking arm 13, make two the first annulus 101 and the second annulus 102 and many Bar linking arm 13 forms multiple honeycomb shaped structure 103 and multiple diamond structure 105.And each honeycomb shaped structure 103 includes two Individual diamond structure, as shown in figure 4, two diamond structures 105 are symmetrical arranged with the cross central line of honeycomb shaped structure 103.
Preferably, as shown in Figures 2 and 3, the horizontal catercorner length (a) of the rhombus of the second annulus 102 is equal to the first circle Two sine waves wavelength (c) of ring 101, longitudinal catercorner length (b) of the rhombus of the second annulus 102 is less than two first annulus 101 longitudinal pitch, makes the second annulus 102 preferably be placed between corresponding two first annulus 101, makes honeycomb shaped structure 103 More stable.
In the present embodiment, as shown in Figure 1 and Figure 4, linking arm 13 one end is connected with the crest 11 of the first annulus 101, even The midpoint 14 connecing arm 13 other end with the side of the rhombus of corresponding second annulus 102 of crest 11 of the first annulus 101 connects, and makes four One rhombus of the crest 11 of individual first annulus 101 and the second annulus 102 and four linking arms 13 form a honeycomb shaped structure 103, the crest 11 of two the first annulus is formed with the half on two sides of a rhombus of the second annulus 102 and two linking arms 13 One diamond structure 105.This structure, makes the rhombus of the second annulus 102 become the attachment structure between linking arm 13, the second circle Longitudinal summit 15 of the rhombus of ring 102 is located just at the centre of two crests 11, enhancing structural stability, can strengthen support Radial support power.And connected by X-shaped structure between two honeycomb shaped structure 103, make equally steady between honeycomb shaped structure 103 Fixed.
Preferably, honeycomb shaped structure 103 a pair of linking arm 13 along the circumferential direction is in bracket shape, the one of mark in such as Fig. 4 To linking arm 13, the angle longitudinally projecting of the rhombus of the second annulus 102 under making a pair of linking arm 13 can accommodate, structure is more steady Fixed.
The support 100 of the present invention is made up of polymeric material, this material need to comprise decompose group can with surrounding tissue, Liquid (as blood vessel) has the good compatibility.Polymeric material armarium need to slowly decompose the tissue avoiding causing restenosiss Over loading or inflammatory reaction.For example:The support 100 of the present invention can be made up of polylactic acid.
The support 100 of the present invention at least has an additional or embedded identification labelling 104, and identification labelling 104 can be Roentgenopaque pointing object or tablet, make roentgenopaque pointing object or tablet can be attached to the surface of support 100 Or inlay wherein, detect or identify the purpose of support 100 to reach after the implantation.
Fig. 5 illustrates the state after support 100 expansion.
Fig. 6 illustrates form on dilating sacculus for the support 100, after sacculus is withdrawn from, that is, as shown in Figure 5.
Fig. 7 illustrates support 100 implantation X-ray image figure after 6 months for the pig arteria coronaria, and the blood vessel wall of display implantation is smooth, no Any angiostenosiss mode.
Fig. 8 illustrates support 100 implantation ivus image display figure after 6 months for the Sanguis sus domestica pipe, and what display was implanted props up Frame struts completely, no any retraction.
Fig. 9 illustrate support 100 insert latter 6 months pathological section it was demonstrated that:Support struts fabulous, no retraction, fracture etc. Phenomenon occurs.
Embodiment 2
As shown in Figure 10, the present embodiment and the difference of embodiment 1 are:Linking arm 13 one end and the first annulus 101 Crest 11 connect, the longitudinal direction of linking arm 13 other end and the rhombus of corresponding second annulus 102 of crest 11 of the first annulus 101 Summit 15 connects, and makes the crest 11 of four the first annulus 101 be connected the X-shaped being formed with two rhombuses of second annulus 102 Structure and four linking arms 13 form a honeycomb shaped structure 103, and the crest 11 of two the first annulus 101 and the second annulus 102 one side of two rhombuses and two linking arms 13 form a diamond structure 105.This structure, makes the second annulus 102 X-shaped structure becomes the attachment structure between linking arm 13, enhances structural stability, can strengthen the radial support power of support.
Preferably, the horizontal catercorner length of the rhombus of the second annulus 102 is equal to a sine wave ripple of the first annulus 101 Long, longitudinal catercorner length of the rhombus of the second annulus 102 is less than the longitudinal pitch of two first annulus 101, makes the second annulus 102 Preferably it is placed between corresponding two first annulus 101, make honeycomb shaped structure 103 more stable.
Finally it should be noted that above example is only in order to illustrating technical scheme, rather than the present invention is protected The restriction of shield scope, although having made to explain to the present invention with reference to preferred embodiment, those of ordinary skill in the art should Work as understanding, technical scheme is modified or equivalent, all belong to protection scope of the present invention.

Claims (10)

1. a kind of biodegradable drug stent, in a tubular form, including multiple the first annulus along longitudinal arrangement, this first for this support Annulus is in sinusoidal wave form in circumferencial direction, and multiple first annulus is along longitudinally-aligned;It is characterized in that:Two along longitudinally adjacent It is provided with the second annulus, this second annulus is connected and composed by the cincture of multiple rhombuses in circumferencial direction between first annulus, and two Individual first annulus, along being longitudinally respectively connected with a linking arm between the crest and the second annulus of this second annulus, makes two the One annulus and the second annulus and a plurality of linking arm form multiple honeycomb shaped structure and multiple diamond structure, and each honeycomb knot Structure includes two diamond structures, and this two diamond structures are symmetrical arranged with the cross central line of honeycomb shaped structure.
2. biodegradable drug stent according to claim 1 it is characterised in that:Linking arm one end and the first annulus Crest connects, and the midpoint on the side of rhombus of the linking arm other end second annulus corresponding with the crest of this first annulus connects, and makes One rhombus of the crest of four the first annulus and the second annulus and four linking arms form honeycomb shaped structure, and two the The half on two sides of one rhombus of the crest of one annulus and the second annulus and two linking arms form a diamond structure.
3. biodegradable drug stent according to claim 2 it is characterised in that:The rhombus of the second annulus laterally right Diagonal length is equal to two sine wave wavelength of the first annulus, and longitudinal catercorner length of the rhombus of the second annulus is less than two first The longitudinal pitch of annulus.
4. biodegradable drug stent according to claim 1 it is characterised in that:Linking arm one end and the first annulus Crest connects, and longitudinal summit of the rhombus of the linking arm other end second annulus corresponding with the crest of this first annulus connects, and makes The crest of four the first annulus is connected the X-shaped structure being formed with two rhombuses of second annulus and four linking arms form one Individual honeycomb shaped structure, and two rhombuses and two linking arms of the crest of two the first annulus and the second annulus form one Individual diamond structure.
5. biodegradable drug stent according to claim 4 it is characterised in that:The rhombus of the second annulus laterally right Diagonal length is equal to a sine wave wavelength of the first annulus, and longitudinal catercorner length of the rhombus of the second annulus is less than two first The longitudinal pitch of annulus.
6. the biodegradable drug stent according to claim 2 or 4 it is characterised in that:This honeycomb shaped structure is circumferentially A pair of linking arm in direction is in bracket shape.
7. the biodegradable drug stent according to claim 2 or 4 it is characterised in that:First annulus is by multiple V-arrangements Ripple is constituted, and the ripple of this V-arrangement has crest and the swing wall positioned at this crest both sides.
8. the biodegradable drug stent according to claim 2 or 4 it is characterised in that:This support is made up of polylactic acid.
9. the biodegradable drug stent according to claim 2 or 4 it is characterised in that:This support at least has one Additional or embedded identification labelling.
10. biodegradable drug stent according to claim 9 it is characterised in that:This identification is labeled as impermeable X-ray Pointing object or tablet.
CN201410410095.4A 2014-08-19 2014-08-19 Biodegradable drug stent Active CN105012059B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201410410095.4A CN105012059B (en) 2014-08-19 2014-08-19 Biodegradable drug stent
PCT/CN2014/092641 WO2016026235A1 (en) 2014-08-19 2014-12-01 Biodegradable drug stent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410410095.4A CN105012059B (en) 2014-08-19 2014-08-19 Biodegradable drug stent

Publications (2)

Publication Number Publication Date
CN105012059A CN105012059A (en) 2015-11-04
CN105012059B true CN105012059B (en) 2017-02-15

Family

ID=54402621

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201410410095.4A Active CN105012059B (en) 2014-08-19 2014-08-19 Biodegradable drug stent

Country Status (2)

Country Link
CN (1) CN105012059B (en)
WO (1) WO2016026235A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108938161B (en) * 2017-11-17 2021-07-06 杭州唯强医疗科技有限公司 Peripheral blood vessel stent
CN109124838B (en) * 2018-08-24 2024-01-30 四川大学 V-shaped degradable biological rack

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1029517A2 (en) * 1999-01-14 2000-08-23 Medtronic Inc. Staggered endoluminal stent
WO2005051238A1 (en) * 2003-11-27 2005-06-09 Forschungszentrum Karlsruhe Gmbh Compression sleeve
US7500988B1 (en) * 2000-11-16 2009-03-10 Cordis Corporation Stent for use in a stent graft
CN101732116A (en) * 2008-11-15 2010-06-16 微创医疗器械(上海)有限公司 Intravascular stent used for repairing lesion blood vessel
CN105682614A (en) * 2014-01-28 2016-06-15 日本来富恩株式会社 Stent

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19717475C1 (en) * 1997-04-25 1998-09-03 Heraeus Gmbh W C Radially expandable support structure or stent for tubular vessel in body
US6264685B1 (en) * 1999-07-06 2001-07-24 Datascope Investment Corp. Flexible high radial strength stent
US20030074051A1 (en) * 2001-10-16 2003-04-17 Kirsten Freislinger Luehrs Flexible stent
US20120277844A1 (en) * 2006-08-22 2012-11-01 Tim Wu Biodegradable Drug Eluting stent Pattern
US8926688B2 (en) * 2008-01-11 2015-01-06 W. L. Gore & Assoc. Inc. Stent having adjacent elements connected by flexible webs
CN204169960U (en) * 2014-08-19 2015-02-25 东莞天天向上医疗科技有限公司 A kind of biodegradable drug stent

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1029517A2 (en) * 1999-01-14 2000-08-23 Medtronic Inc. Staggered endoluminal stent
US7500988B1 (en) * 2000-11-16 2009-03-10 Cordis Corporation Stent for use in a stent graft
WO2005051238A1 (en) * 2003-11-27 2005-06-09 Forschungszentrum Karlsruhe Gmbh Compression sleeve
CN101732116A (en) * 2008-11-15 2010-06-16 微创医疗器械(上海)有限公司 Intravascular stent used for repairing lesion blood vessel
CN105682614A (en) * 2014-01-28 2016-06-15 日本来富恩株式会社 Stent

Also Published As

Publication number Publication date
WO2016026235A1 (en) 2016-02-25
CN105012059A (en) 2015-11-04

Similar Documents

Publication Publication Date Title
CN103945796B (en) Grid
CN102068331A (en) Bifurcate blood vessel stent
US11564816B2 (en) Radially rigid and longitudinally flexible multi-element intravascular stent
CN103930074A (en) Biodegradable drug-eluitng stent patten
CN102462563A (en) Furcated blood vessel stent
ITTO970369A1 (en) ANGIOPLASTIC STENT
CN105012059B (en) Biodegradable drug stent
CN101579268B (en) Reticulated endovascular stent
CN105796218A (en) Covered stent
ES2844198T3 (en) Oblique stent
CN203662949U (en) Lower extremity artery blood vessel stent
CN206934212U (en) Overlay film frame
CN206566053U (en) A kind of effective biological support of coronary blood
CN204618497U (en) A kind of Biodegradable scaffold
CN203790082U (en) Film-coated intravascular stent
CN105769398B (en) Biodegradable vascular scaffold based on polyhedron deformation mechanism
CN204169960U (en) A kind of biodegradable drug stent
CN112773585A (en) Implant stent
CN111228000B (en) Lumen stent
CN203122690U (en) Vertebral artery support
CN103110465B (en) Magnesium alloy coronary support frame
CN105853036A (en) Degradable individual non-column-shaped bionic medicine eluting coronary stent
KR100779838B1 (en) Stent
CN213489573U (en) Be applied to novel intravascular stent of carotid
CN204411036U (en) Intravascular stent

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant