CN104887234A - Method for evaluating continuous airway obstruction of low physiological workloads - Google Patents

Abstract

The invention discloses a method for evaluating continuous airway obstruction of low physiological workloads, which comprises the steps: chest strap signals Tho and corset strap signals Abd are collected by adopting a chest and corset strap sensor, a lung volume change token state dVlu,e is counted through dVlu, e=0.3Tho+Abd, a breathing air quality token state dmlu,e is collected by adopting a thermosensitive oro-nasal air flow sensor, the dVlu,e and the dmlu,e are made into a two-dimensional diagram, thereby obtaining situation information of stricture and obstruction of relative respiratory tracts when breathing, the dVlu,e and the dmlu,e are used to count correlation, values of linearly dependent coefficients characterize obstruction or stricture degrees of the respiratory tracts, the chest strap signals Tho and the corset strap signals Abd are increased when inhaling, and the dmlu,e is increased when inhaling. The method for evaluating the continuous airway obstruction of low physiological workloads has the advantages of low cost, small physiological workloads and long-time continuous monitoring, and enables users to quantitatively evaluate the obstruction of the respiratory tracts and stricture degree of air passages when the users are in a natural sleep state.

Description

A kind of continuous print airway obstruction appraisal procedure of low physiological stress and device

Technical field

The present invention relates to medical instruments field, more specifically, relate to a kind of continuous print airway obstruction appraisal procedure and device of low physiological stress.

Background technology

Sleep Apnea-hypopnea Syndrome (Sleep Apnea Hypopnea Syndrome, SAHS) in recent years in progressively rising, it refers to asphyxia recurrent exerbation more than 30 times or apnea hypopnea indexes (AHI) >=5 time/hour with the clinical symptoms such as drowsiness in sleep procedure every night.This symptom is divided into maincenter type (CSAS), obstructive type (OSAS) and mixed type (MSAS) three kinds, there is snoring when it can cause patient sleeps and with asphyxia and (or) hypopnea (low ventilation), suppress the symptoms such as awake, Excessive daytime sleepiness and nighttime sleep structural deterioration, in addition also may cause or increase the weight of the diseases such as pulmonary hypertension, pulmonary heart disease, respiratory failure, hypertension, arrhythmia, apoplexy.SAHS greatly have impact on the quality of life of patient, is familiar with gradually in recent years and payes attention to by people.

Nowadays hospital's Sleeping Center adopts sleep analysis monitor (Polysomnography, PSG) to carry out the diagnosis of Sleep Apnea-hypopnea Syndrome SAHS, and PSG is that sleep apnea syndrome detects and sleep monitor " goldstandard ".In SAHS patient, OSAS and MSAS is in the great majority, and simple CSAS is more rare, is generally no more than 10% of apnea patient, also has report to only have 4%, OSAS needs of patients is measured to the congestion situations of air flue.

For the measurement of airway obstruction situation, analytical method, current clinical practice have following several method: pharyngeal cavity physical examination, cephalometric analysis, epithelium healing CT and 3-dimensional image nuclear magnetic resonance, NMR (MRI), Miao Le tests, determination of airway resistance in respiratory waveform analysis, the monitoring of nose air-flow and the sleep monitor system containing respirometric information.

Pharyngeal cavity physical examination: gently press 2/3 place before patient's tongue with spatula, advise patient to send out " " sound, observes soft palate motion conditions, and check bilateral palatoglossal arch, palatopharyngeal arch, lateral pharyngeal band and pharynx rear wall, both sides palatine tonsil, tooth, tongue, soft palate, hard palate etc. have without exception.Some patients pharyngeal reflex is more responsive, first can spray after pharyngeal row topical anesthesia with 1% tetracaine and reexamine.

Cephalometric analysis: x-ray cephalometry (Cephalometrics), mainly measure x-ray head location to take pictures the image of gained, certain line angle is depicted to tooth jaw, each index point in cranium face and carries out Measurement and analysis diagnosis and to be deep in inner skeletal structure by configuration of surface and to go.

Epithelium healing CT and 3-dimensional image nuclear magnetic resonance, NMR (MRI) with belong to medical image processing method, by the scanning two-dimensional image data of CT or MRI, carried out three-dimensional reconstruction and the analysis of epithelium healing by image software, analyze congestion situations and the obstructive position of epithelium healing.

Examination of fibre endoscope under Miao Le (mullers) experiment and waking state: the local anesthesia first making nasal cavity pharyngeal cavity of 1% tetracaine, allow patient's eupnea, fiberoptic laryngoscope head is placed in root of the tongue level, advise it to remain silent to pinch nose and do dark aspiratory action, examine the situation that each wall of pharyngeal cavity and the root of the tongue are shifted to the midline.Estimate the change of cavum laryngopharyngeum cross-sectional area and the degree of minimizing, record with the form of percentage ratio.Pumpback camera lens is a little more than soft palate level again, can clear view be advisable to uvula and soft palate activity during eupnea.Advise patient to pinch nose to remain silent dark air-breathing, observe uvula, soft palate, the situation that lateral wall of pharynx is shifted to the midline and the situation that palate pharynx gap sectional area reduces, record with the form of percentage ratio.Above inspection method carries out 2 ~ 3 times repeatedly, to determine operative site and modus operandi.Miao Le experiment can be combined with fiberoptic laryngoscope observes airway obstruction situation.

The monitoring of mouth and nose air-flow can monitor the respiratory air flow situation of subjects; whether sleep apnea occurs in conjunction with the breast bellyband information identifiable design in sleep analysis monitor (PSG), and the sleep apnea occurred is maincenter type asphyxia or obstructive type asphyxia.

Determination of airway resistance in respiratory waveform analysis: airway resistance is in respiratory, the viscous drag of air-flow by producing during respiratory tract, usually pass through 1L tolerance with per second, the pressure differential caused at alveolar and airway open place represents.Which kind of recording instrument is parameters generally need adopt measure.The resistance of respiratory system presses anatomical position classification, can be divided into nasal resistance, oral cavity resistance, bottleneck throat resistance, Airway resistance, bronchial resistance, alveolar and lung tissue resistance, thorax resistance etc.Respiratory volume tracing (be called for short body retouch) is the only method directly can measuring person's windpipe resistance at present.Method of testing: 1, allows more than 4 cycles of experimenter's eupnea, in the hope of the functional residual capacity position at eupnea end.2, allow at normal respiration end experimenter do shallow fast breathing, notice that observing respiratory flow-case buckles line, record 4 reproducible breathing rings.3, at shallow fast breathing end and then down interface valve, allow experimenter continue to keep shallow fast breathing several cycle, recording mouth pressure-case pressure relation curve.4, after completing shallow fast breathing, part body is retouched instrument and still can be continued to measure slow vital capacity, measures inspiratory capacity and deep breathing volume according to experimenter's situation, and graded measures or completes without a break.Slow vital capacity measures and is used for calculating the index such as total lung capacity, residual volume further.5, repetition measurement at least 3 times surely, 3 results choosing oral cavity pressure-case pressure relation curve, flow-case pressure relation curve and slow vital capacity curve all good are preserved.< 10% is answered in the variation of airway resistance.6, result calculates: existing body is retouched instrument and is all equipped with computer, can result of calculation automatically.The Thorax volume of the meansigma methods reflection experimenter of the result that 3 suboptimums detect and airway resistance.

Adopt the monitoring of mouth and nose air-flow and the sleep monitor system containing respirometric information, by the analysis of nose air flow information, whether sleep apnea (SAHS) occurs, comprehensively analyzed by breast bellyband signal acquisition breast abdomen movable information and can distinguish obstructive type (OSAS) and maincenter type (CSAS) sleep apnea.

The existing measuring method to respiratory tract obstruction and stenosis roughly has three kinds: 1, image method (comprise x-ray, CT, and MRI, these means quantitatively can obtain respiratory tract obstruction and narrow situation accurately, but the airway obstruction situation that these means are not suitable for long-time continuous is measured.2, pharyngeal cavity physical examination, the routine examination methods such as Miao Le tests, the determination of airway resistance in respiratory waveform analysis, it needs the cooperation of measured's sense of independence.Be unsuitable for long-time continuous measurement to be also difficult to measure when measured's sleep state.3, adopt the monitoring of mouth and nose air-flow and the sleep monitor system containing respirometric information to be applicable to long-time measurement.But related application and research carry out the differentiation of obstructive type (OSAS) and maincenter type (CSAS) sleep apnea by means of only these two kinds of signals, but do not adopt the signal of sleep monitor to calculate at present, to measure or the related application of quantitative evaluation respiratory tract obstruction situation or airway constriction situation and theoretical research are reported.

Summary of the invention

In order to overcome the deficiencies in the prior art, first the present invention proposes a kind of continuous print airway obstruction appraisal procedure of low physiological stress, the method has that cost is low, physiological stress is little, can the feature of long-time continuous monitoring, can to user quantitative evaluation to respiratory tract obstruction and airway constriction degree when natural sleep state.

Another object of the present invention is the continuous print airway obstruction apparatus for evaluating proposing a kind of low physiological stress.

To achieve these goals, technical scheme of the present invention is:

A continuous print airway obstruction appraisal procedure for low physiological stress, comprising:

S1. pectoral girdle signal Tho and bellyband signal Abd is gathered respectively, according to formula dV by breast bellyband sensor _{lu, e}=1.3Tho+Abd calculates the token state dV of lung volume change _{lu, e};

S2. the collection of temperature-sensitive mouth and nose pneumatic sensor is adopted to characterize the air quality dm passing in and out respiratory system in respiratory _{lu, e};

S3. to characterize the amount dV of lung volume change _{lu, e}and dm _{lu, e}doing X-Y scheme, obtaining the upper airway stricture relevant to breathing phase and the situation information of obstruction; To characterize the amount dV of lung volume change _{lu, e}and dm _{lu, e}do correlation calculations, the numerical representation method respiratory tract obstruction of linearly dependent coefficient or narrow degree;

Above-mentioned pectoral girdle signal Tho and bellyband signal Abd increases when air-breathing, dm _{lu, e}increase when air-breathing.

Preferably, above-mentioned pectoral girdle signal Tho, bellyband signal Abd and characterize in respiratory the air quality dm passing in and out respiratory system _{lu, e}sample frequency be greater than 10Hz.

Preferably, described step S3 records the dV characterizing lung volume change to breast bellyband signal _{lu, e}and the signal dm of temperature-sensitive mouth and nose pneumatic sensor _{lu, e}the computing formula (1) of linearly dependent coefficient is adopted to calculate its linearly dependent coefficient;

$r=\underset{i=1}{\overset{n}{\mathrm{\&Sigma;}}}({\mathrm{dV}}_{\mathrm{lu},e,i}-\stackrel{\&OverBar;}{{\mathrm{dV}}_{\mathrm{lu},e}})({\mathrm{dm}}_{\mathrm{lu},e,i}-\stackrel{\&OverBar;}{{\mathrm{dm}}_{\mathrm{lu},e}})/\sqrt{\underset{i=1}{\overset{n}{\mathrm{\&Sigma;}}}{({\mathrm{dV}}_{\mathrm{lu},e,i}-\stackrel{\&OverBar;}{{\mathrm{dV}}_{\mathrm{lu},e}})}^2\&CenterDot;\underset{i=1}{\overset{n}{\mathrm{\&Sigma;}}}{({\mathrm{dm}}_{\mathrm{lu},e,i}-\stackrel{\&OverBar;}{{\mathrm{dm}}_{\mathrm{lu},e}})}^2}---\left(1\right)$

DV _{lu, e, i}represent i-th lung volume change token state, dm _{lu, e, i}represent i-th breathing gas quality characterization amount, represent the meansigma methods of lung volume change token state, represent the meansigma methods of gaseous mass token state.

Close to numerical value 1, linearly dependent coefficient more represents that respiratory tract is more unobstructed, linearly dependent coefficient more away from 1, close to 0 represent airway constriction or airway obstruction more serious.

Preferably, when doing X-Y scheme, be draw a period with time T1, namely draw as X, Y variable using the lung volume change information of T1 and temperature-sensitive mouth and nose air flow information; Or be draw a period with the single breath cycle;

When doing correlation calculations, carry out calculating with time T2 period or be calculate a period with the single breath cycle.

A continuous print airway obstruction apparatus for evaluating for low physiological stress, comprising:

Temperature-sensitive mouth and nose pneumatic sensor, critesistor treatment circuit, breast bellyband sensor, breast bellyband signal processing circuit, analog quantity-digital quantity modular converter and central processing module; Described temperature-sensitive mouth and nose pneumatic sensor is by critesistor treatment circuit access analog quantity-digital quantity modular converter, breast bellyband sensor accesses analog quantity-digital quantity modular converter by breast bellyband signal processing circuit, the output termination central processing module of analog quantity-digital quantity modular converter.

Preferably, breast bellyband sensor comprises first and second piezoelectric type pectoral girdle or scalable impedance type bellyband.

Compared with prior art, beneficial effect of the present invention is:

1) the present invention adopts breast bellyband innovatively, temperature-sensitive air-flow is as input signal, the measurement of breast bellyband signal and mouth and nose airflow signal all can be carried out continuously for a long time, physiological stress is tested much smaller than Miao Le, cost, far below shadowgraph technique, can realize the monitoring of the unredeemed respiratory tract obstruction situation the whole night of prior art.The present invention can monitor epithelium healing under the prerequisite not disturbing experimenter's natural sleep state, and this is that the shadowgraph technique harmony reflection technology that can only be used under waking state and the Miao Le experiment institute that can interfere with natural sleep state are inaccessiable;

2) X-Y scheme is done with lung volume token state and breathing gas quality characterization amount, pass through pattern analysis, epithelium healing stenosis can be obtained with the information of breathing Temporal variation, when a certain breathing phase occurs that epithelium healing is narrow, when the breathing of correspondence, phase images can observe curve " platform ", the airway constriction situation that this X-Y scheme can be used in observing experimenter is easily sent out in inspiratory phase or expiratory phase, in general the airway constriction of OSAS patient more easily betides inspiratory phase compared with normal person, the present invention's lung volume token state and breathing gas quality characterization X-Y scheme that amount is done can be used in preliminary examination OSAS,

3) make linear correlation to lung volume token state and breathing gas quality characterization amount to calculate, linearly dependent coefficient can analyze the size of epithelium healing sectional area quantitatively, thus realize the quantitative evaluation of the real-time continuous of respiratory tract obstruction and stenosis, for the size of demarcating epithelium healing sectional area with linearly dependent coefficient provides possibility.

Accompanying drawing explanation

Fig. 1 is the part scheme of installation of device of the present invention.

Fig. 2 is structural representation of the present invention.

Fig. 3 is schematic flow sheet of the present invention.

Fig. 4 is each signal curve schematic diagram of actual measurement.

Fig. 5, the 6 equivalent m-V ring schematic diagrams obtained for actual measurement.

Detailed description of the invention

Below in conjunction with accompanying drawing, the present invention will be further described, but embodiments of the present invention are not limited to this.

The present invention is directed to the shortcoming of existing measurement means: involve great expense, have wound or physiological stress larger, monitoring or interference experimenter ortho sleep state etc. only can be received under waking state, employing cost is lower and the breast bellyband sensor that physiological stress is less and temperature-sensitive pneumatic sensor can realize measurement at night the whole night, calculated by breast bellyband signal and characterize the lung volume change that respiratory movement causes, adopt the air quality passing in and out respiratory system in the characterization respiratory of temperature-sensitive mouth and nose pneumatic sensor, the information of lung volume change is characterized as abscissa (X-axis) using breast bellyband, with the air quality of the turnover respiratory system of temperature-sensitive mouth and nose air-flow sign for vertical coordinate (Y-axis) is drawn, the shape representation of figure is in the congestion situations of breathing phase, figure occurs that " platform " then illustrates that the narrow and small degree of epithelium healing is larger, the obstruction of the size quantitative evaluation respiratory tract of the linearly dependent coefficient of X-Y and stenosis, the stenosis of the less epithelium healing of linearly dependent coefficient is larger.

Breast bellyband sensor and temperature-sensitive mouth and nose pneumatic sensor is adopted to measure, calculated by breast bellyband signal and characterize the lung volume change that respiratory movement causes, adopt the air quality passing in and out respiratory system in the characterization respiratory of temperature-sensitive mouth and nose pneumatic sensor, the information of lung volume change is characterized as abscissa (X-axis) using breast bellyband, with the air quality of the turnover respiratory system of temperature-sensitive mouth and nose air-flow sign for vertical coordinate (Y-axis) is drawn, the shape representation of figure is breathing obstruction and the airway constriction situation of phase, the degree of congestion of the size quantitative evaluation respiratory tract of the linearly dependent coefficient of X-Y.

Breast bellyband and mouth and nose air-flow are led and be arranged on subjects's mouth and nose end, the move principle of the installation of leading of breast abdominal respiration is: keep certain tension force, and fixedly secure.The position of patient during installation: patient is preferably in dorsal position, can avoid the displacement of the maximum abdominal circumference plane caused by the change of position so effectively.The position that pectoral girdle is laid and fixing: the principle of installation is mounted in " maximum breathing plane of movement ".Generally be arranged between the 5th rib and the 6th rib, abdominal part leads to be arranged on by umbilicus and opens a palm place.The principle of laying mouth and nose pneumatic sensor is, the critesistor on sensor must be made to be placed in the place that can touch air-flow.Because great majority snoring patient at night is mouth breathing state, so guarantee to detect that oral airflow seems still for important.The mouth and nose air-flow of three critesistor is preferably adopted to lead, three temperature-sensitives are made to lead contact two nasal cavities and oral airflow respectively, if only have two critesistor, one of them critesistor is made to contact oral airflow, another critesistor can contact oral airflow, another critesistor contacts the nasal cavity of comparatively ventilating, as Fig. 1.

The respiratory air flow information that the present invention adopts the human body respiration motion conditions information of breast bellyband signal acquisition and obtained by temperature-sensitive mouth and nose pneumatic sensor.The circuit hardware design of sensor is as accompanying drawing 2.

100-heat-sensitive type mouth and nose pneumatic sensor; 101-first piezoelectric type pectoral girdle or scalable impedance type breast band; 102-second piezoelectric type bellyband or scalable impedance type bellyband; 103-critesistor treatment circuit; 104-breast bellyband signal processing circuit, adopts the employing piezoelectric transducer treatment circuit of piezoelectric type breast bellyband, adopts the employing impedance transducer treatment circuit of scalable impedance type breast bellyband; 105-analog quantity-digital quantity modular converter, can separately as independently circuit module, and also accessible site is at critesistor treatment circuit 103, in the treatment circuit of breast bellyband signal processing circuit 104 or be integrated in CPU 106.106-CPU (CPU) can be PC also can be other control system, mainly in order to record data and to realize the realization of software algorithm.

Workflow of the present invention is as accompanying drawing 3:

If represent the chest exercise recorded by pectoral girdle signal with Tho, Abd represents the abdominal exercise recorded by bellyband signal, and setting Tho and Abd increases when air-breathing, and the amount characterizing lung volume change is set to dV _{lu, e}, dV _{lu, e}by relational expression dV _{lu, e}=1.3Tho+Abd calculates.

Adopt the air quality dm passing in and out respiratory system in the characterization respiratory of temperature-sensitive mouth and nose pneumatic sensor _{lu, e}, setting dm _{lu, e}increase when air-breathing.

Advise that the sample rate of each signal is more than 10Hz.

Fig. 4 is each signal curve of actual measurement, and the dV calculated _{lu, e}.

(1) to characterize the variable dV of lung volume change _{lu, e}and the signal of temperature-sensitive mouth and nose pneumatic sensor does X-Y scheme, the shape representation of figure is breathing obstruction and the airway constriction situation of phase:

The lung volume change dV characterized with breast bellyband _{lu, e}as abscissa (X-axis), the air quality dm of the turnover respiratory system characterized with temperature-sensitive mouth and nose air-flow _{lu, e}for vertical coordinate (Y-axis) is drawn, the correspondence that the degree of congestion of the shape representation upper respiratory tract of figure and obstruction occur breathes phase.The sleep stage standard that can refer to U.S.'s sleep medicine meeting (AASM) is namely drawn using T1=30s as a period (epoch), namely using the lung volume change information of 30s and temperature-sensitive mouth and nose air flow information as X, Y variable is drawn, and also can be draw a period in the single breath cycle.Under same coordinate axes yardstick, more close to straight line, then respiratory tract is more unobstructed for this figure, and this figure gets over off-straight, close to taper or triangle or rhombus, then illustrate respiratory tract obstruction or narrow, the axis of small circle of its approximate cone-shape is larger, airway obstruction or airway constriction more serious.Figure clockwise one week is a breathing cycle, and rising edge is inspiratory phase, and trailing edge, for breathing phase, if left upper end projection, namely occurs " platform " at rising edge end, then represent that air-breathing airway constriction or airway obstruction occurs at latter stage; Corresponding, if figure is in bottom righthand side projection, namely there is " platform " at trailing edge end, then represent EEP generation airway constriction or airway obstruction; If figure, in left upper end and the equal projection of bottom righthand side, namely all occurs " platform " at the end of rising edge and trailing edge, then represent that airway constriction or airway obstruction all occur for air-breathing latter stage and EEP, as accompanying drawing 5, the equivalent V-m ring that accompanying drawing 6 obtains for actual measurement.

(2) to characterize the variable dV of lung volume change _{lu, e}and the signal of temperature-sensitive mouth and nose pneumatic sensor does linear correlation calculating, the numerical representation method respiratory tract obstruction of linearly dependent coefficient or narrow degree.

Breast bellyband signal is recorded to the dV characterizing lung volume change _{lu, e}and the signal dm of temperature-sensitive mouth and nose pneumatic sensor _{lu, e}the computing formula (1) of linearly dependent coefficient is adopted to calculate its linearly dependent coefficient.

$r=\underset{i=1}{\overset{n}{\mathrm{\&Sigma;}}}({\mathrm{dV}}_{\mathrm{lu},e,i}-\stackrel{\&OverBar;}{{\mathrm{dV}}_{\mathrm{lu},e}})({\mathrm{dm}}_{\mathrm{lu},e,i}-\stackrel{\&OverBar;}{{\mathrm{dm}}_{\mathrm{lu},e}})/\sqrt{\underset{i=1}{\overset{n}{\mathrm{\&Sigma;}}}{({\mathrm{dV}}_{\mathrm{lu},e,i}-\stackrel{\&OverBar;}{{\mathrm{dV}}_{\mathrm{lu},e}})}^2\&CenterDot;\underset{i=1}{\overset{n}{\mathrm{\&Sigma;}}}{({\mathrm{dm}}_{\mathrm{lu},e,i}-\stackrel{\&OverBar;}{{\mathrm{dm}}_{\mathrm{lu},e}})}^2}---\left(1\right)$

DV _{lu, e, i}represent i-th lung volume change token state, dm _{lu, e, i}represent i-th breathing gas quality characterization amount, represent the meansigma methods of lung volume change token state, represent the meansigma methods of gaseous mass token state.Close to numerical value 1, linearly dependent coefficient more represents that respiratory tract is more unobstructed, linearly dependent coefficient is more away from 1, close to 0 represent airway constriction or airway obstruction more serious, in like manner, the sleep stage standard that can refer to U.S.'s sleep medicine meeting (AASM) namely calculates using T2=30s as a period (epoch), can be also calculate a period with the single breath cycle.

Adopt the method can long-time continuous, monitor the airway constriction of measured under natural sleep state or congestion situations quantitatively, dynamically.

The Pulmonary volume that the present invention adopts breast bellyband signal to calculate characterizes the breathing gas quality characterization amount recorded with mouth and nose temperature-sensitive and does X-Y scheme, by the Pulmonary volume token state-shape discrimination respiratory tract obstruction of breathing gas quality characterization amount institute generating writing pattern and the method for the situation of upper airway stricture and the breathing phase of respiratory tract obstruction and narrow generation, and characterize respiratory tract obstruction and stenosis quantitatively by the method for the linearly dependent coefficient calculating Pulmonary volume token state and breathing gas quality characterization amount.

The present invention adopts the breast bellyband signal and temperature-sensitive mouth and nose airflow signal generally applied in sleep monitor as input, lung inner volume change information is characterized by breast bellyband signal result of calculation, the token state of the breathing gas quality obtained with temperature-sensitive mouth and nose airflow signal makes X-Y scheme, breathing phase when differentiating the situation of respiratory tract obstruction and upper airway stricture and respiratory tract obstruction and narrow generation by the curve shape of X-Y scheme, by both the quantitative evaluation respiratory tract obstruction of linearly dependent coefficient size and stenosis.

Compared with prior art, the invention has the advantages that:

1) the input signal breast bellyband signal of the present invention's employing, the mouth and nose gas flow measurement of heat sensitive sensor is all can the signal measured of long-time continuous, and cost and physiological stress are less than the technological means of existing monitoring epithelium healing, therefore the information of respiratory tract obstruction situation can be obtained for a long time, when can be applicable to natural sleep state, thus the monitoring of the unredeemed respiratory tract obstruction situation the whole night of prior art can be realized, respiratory tract obstruction and stenosis can be assessed quantitatively in real time the whole night.

2) make X-Y scheme with lung volume token state and breathing gas quality characterization amount, by the analysis to figure, can obtain epithelium healing stenosis with the information of breathing Temporal variation, researcher observation and analysis be convenient in patterned record.

3) make linear correlation to lung volume token state and breathing gas quality characterization amount to calculate, linearly dependent coefficient can analyze the size of epithelium healing sectional area quantitatively, and this linearly dependent coefficient of the present invention is provide possibility by the size of linearly dependent coefficient demarcation epithelium healing sectional area.

Above-described embodiments of the present invention, do not form limiting the scope of the present invention.Any amendment done within spiritual principles of the present invention, equivalent replacement and improvement etc., all should be included within claims of the present invention.

Claims (6)

1. a continuous print airway obstruction appraisal procedure for low physiological stress, is characterized in that, comprising:

S1. pectoral girdle signal Tho and bellyband signal Abd is gathered respectively, according to formula dV by breast bellyband sensor _{lu, e}=1.3Tho+Abd calculates the token state dV of lung volume change _{lu, e};

S2. the collection of temperature-sensitive mouth and nose pneumatic sensor is adopted to characterize the air quality dm passing in and out respiratory system in respiratory _{lu, e};

S3. to characterize the amount dV of lung volume change _{lu, e}and dm _{lu, e}doing X-Y scheme, obtaining the upper airway stricture relevant to breathing phase and the situation information of obstruction; To characterize the amount dV of lung volume change _{lu, e}and dm _{lu, e}do correlation calculations, the numerical representation method respiratory tract obstruction of linearly dependent coefficient or narrow degree;

Above-mentioned pectoral girdle signal Tho and bellyband signal Abd increases when air-breathing, dm _{lu, e}increase when air-breathing.

2. the airway obstruction appraisal procedure the whole night of low physiological stress according to claim 1, is characterized in that, above-mentioned pectoral girdle signal Tho, bellyband signal Abd and characterize in respiratory the air quality dm passing in and out respiratory system _{lu, e}sample frequency be greater than 10Hz.

3. the airway obstruction appraisal procedure the whole night of low physiological stress according to claim 1, is characterized in that, described step S3 records the dV characterizing lung volume change to breast bellyband signal _{lu, e}and the signal dm of temperature-sensitive mouth and nose pneumatic sensor _{lu, e}the computing formula (1) of linearly dependent coefficient is adopted to calculate its linearly dependent coefficient; $r=\underset{i=1}{\overset{n}{\mathrm{\&Sigma;}}}({\mathrm{dV}}_{\mathrm{lu},e,i}-\stackrel{\&OverBar;}{{\mathrm{dV}}_{\mathrm{lu},e}})({\mathrm{dm}}_{\mathrm{lu},e,i}-\stackrel{\&OverBar;}{{\mathrm{dm}}_{\mathrm{lu},e}})/\sqrt{\underset{i=1}{\overset{n}{\mathrm{\&Sigma;}}}{({\mathrm{dV}}_{\mathrm{lu},e,i}-\stackrel{\&OverBar;}{{\mathrm{dV}}_{\mathrm{lu},e}})}^2\&CenterDot;\underset{i=1}{\overset{n}{\mathrm{\&Sigma;}}}{({\mathrm{dm}}_{\mathrm{lu},e,i}-\stackrel{\&OverBar;}{{\mathrm{dm}}_{\mathrm{lu},e}})}^2}---\left(1\right)$

DV _{lu, e, i}represent i-th lung volume change token state, dm _{lu, e, i}represent i-th breathing gas quality characterization amount, represent the meansigma methods of lung volume change token state, represent the meansigma methods of gaseous mass token state.

Close to numerical value 1, linearly dependent coefficient more represents that respiratory tract is more unobstructed, linearly dependent coefficient more away from 1, close to 0 represent airway constriction or airway obstruction more serious.

4. the airway obstruction appraisal procedure the whole night of low physiological stress according to claim 1, it is characterized in that, when doing X-Y scheme, be draw a period with time T1, namely draw using the lung volume change information of T1 and temperature-sensitive mouth and nose air flow information as X, Y variable; Or be draw a period with the single breath cycle;

When doing correlation calculations, carry out calculating with time T2 period or be calculate a period with the single breath cycle.

5. a continuous print airway obstruction apparatus for evaluating for low physiological stress, is characterized in that, comprising:

Temperature-sensitive mouth and nose pneumatic sensor, critesistor treatment circuit, breast bellyband sensor, breast bellyband signal processing circuit, analog quantity-digital quantity modular converter and central processing module; Described temperature-sensitive mouth and nose pneumatic sensor is by critesistor treatment circuit access analog quantity-digital quantity modular converter, breast bellyband sensor accesses analog quantity-digital quantity modular converter by breast bellyband signal processing circuit, the output termination central processing module of analog quantity-digital quantity modular converter.

6. the airway obstruction apparatus for evaluating the whole night of low physiological stress according to claim 5, is characterized in that, breast bellyband sensor comprises first and second piezoelectric type pectoral girdle or scalable impedance type bellyband.