CN104825150A - Intracranial disease monitoring and treating device - Google Patents
Intracranial disease monitoring and treating device Download PDFInfo
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- CN104825150A CN104825150A CN201510231070.2A CN201510231070A CN104825150A CN 104825150 A CN104825150 A CN 104825150A CN 201510231070 A CN201510231070 A CN 201510231070A CN 104825150 A CN104825150 A CN 104825150A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/03—Detecting, measuring or recording fluid pressure within the body other than blood pressure, e.g. cerebral pressure; Measuring pressure in body tissues or organs
- A61B5/031—Intracranial pressure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/0215—Measuring pressure in heart or blood vessels by means inserted into the body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/0215—Measuring pressure in heart or blood vessels by means inserted into the body
- A61B5/02152—Measuring pressure in heart or blood vessels by means inserted into the body specially adapted for venous pressure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/03—Detecting, measuring or recording fluid pressure within the body other than blood pressure, e.g. cerebral pressure; Measuring pressure in body tissues or organs
- A61B5/036—Detecting, measuring or recording fluid pressure within the body other than blood pressure, e.g. cerebral pressure; Measuring pressure in body tissues or organs by means introduced into body tracts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6852—Catheters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
- A61B5/6868—Brain
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
- A61B5/6876—Blood vessel
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- A61M1/0023—
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M27/00—Drainage appliance for wounds or the like, i.e. wound drains, implanted drains
- A61M27/002—Implant devices for drainage of body fluids from one part of the body to another
- A61M27/006—Cerebrospinal drainage; Accessories therefor, e.g. valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
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Abstract
The application provides a pressure detection and treatment device in organism, the device includes: a pressure detection unit that detects a pressure within a living body to generate an electric signal corresponding to the pressure; a puncture tube having openings at both ends in a longitudinal direction, and configured to introduce or discharge a liquid into or from the living body; an information transceiver that transmits the electric signal generated by the pressure detection unit to the outside of the living body and receives an external command signal; and a liquid storage device connected to an opening at one end of the puncture tube, for storing liquid introduced from the living body and/or for storing liquid introduced into the living body. According to the application, the pressure in the organism can be detected in a convenient mode without carrying out implantation operation for many times, the pressure in the organism can be timely adjusted, medicines for treatment are led into the organism, and the effectiveness and the convenience of treatment are improved.
Description
Technical field
The application relates to technical field of medical instruments, particularly relates to pressure detecting and therapy equipment in a kind of organism.
Background technology
Intracranial pressure (intracranial pressure, ICP) mainly referring to the pressure that intracranial tolerant (mainly comprising the materials such as cerebral tissue, cerebral blood flow and cerebrospinal fluid) produces cranial cavity wall, is the one reflection of intracranial disease or intracranial secondary arthritis.
The continuing to increase of intracranial pressure can cause that cerebral blood flow reduces, cerebral blood supply insufficiency, causes cerebral ischemia, anoxia, as can not Timeliness coverage increased intracranial pressure take effective remedy measures, then may cause serious consequence, even threat to life.Therefore, the monitoring intracranial pressure of all kinds of craniocerebral disease patient, as: craniocerebral trauma, intracranial mass lesion etc., and the intracranial pressure based on this regulates and controls all very important.At present, the monitoring method of intracranial pressure can be divided into and has wound and noinvasive two greatly class clinically.
Although someone proposes the measuring method of multiple intracranial pressure noninvasive, non-invasive methods also exists the features such as measuring accuracy difference, method be loaded down with trivial details and is not widely used.Therefore, monitoring method the most frequently used clinically is at present still for there being wound method, and wherein most widely used is exactly that Intraventricular ICP monitoring is implanted, and its principle is by lateral cerebral ventricle puncture, and monitoring intracranial pressure probe is put into Intraventricular intracranial pressure.The method can also carry out external drainage to ICV cerebrospinal fluid while measurement intracranial pressure, is acknowledged as the goldstandard of monitoring intracranial pressure.
Above it should be noted that, just conveniently to the technical scheme of the application, clear, complete explanation is carried out to the introduction of technical background, and facilitate the understanding of those skilled in the art to set forth.Only can not think that technique scheme is conventionally known to one of skill in the art because these schemes have carried out setting forth in the background technology part of the application.
Summary of the invention
Present inventor finds, the device that above-mentioned Intraventricular ICP monitoring is implanted and monitoring method also exist certain defect, mainly show as 2 points: on the one hand, ICP monitoring device means after implanting and is directly in communication with the outside by the ventricles of the brain, and existence causes the risk of intracranial infection, ICP monitoring probe indwelling time is longer, the probability infected is higher, and therefore general 7 days after surgery tube drawings, cannot retain for a long time, if needs of patients accepts long-term monitoring intracranial pressure, must be interrupted, repeatedly puncture; On the other hand, ICP monitoring device completes monitoring task jointly by intracranial end and cranium external electronic monitoring device two parts after implanting, in the process of carrying out monitoring intracranial pressure, patient must lie in bed, brake, mobility causes considerable restraint, if particularly patient with severe symptoms need carry out emergency treatment CT scan, then must carry cranium external electronic monitoring device simultaneously, in moving process, easily occur that puncture tube slippage, displacement etc. are unexpected.
The application provides pressure detecting and therapy equipment in a kind of organism, when the device of the application being used for detection and the treatment of intracranial pressure, can measure in real time intracranial pressure, also there is the effect of drainage of cerebrospinal fluid and ventricles of the brain administration simultaneously, emergency aid and treatment can be carried out to the complication such as the hydrocephalus of postoperative burst and intracranial infection and associated disease.And, in the organism of the application, pressure detecting and therapy equipment can not only be used for intracranial pressure and detect and the treatment of intracranial disease, also may be used for pressure detecting and the treatment at other positions in organism, such as, may be used for the pressure detecting to vascular venous or tremulous pulse and treatment.
According to an aspect of the embodiment of the present application, provide pressure detecting and therapy equipment in a kind of organism, can be placed in organism, for detecting the pressure in organism, and treat organism, this device comprises:
Pressure sensing cell, it is when being placed in described organism, detects the pressure in organism, to generate the signal of telecommunication corresponding with described pressure;
Puncture tube, it has the opening at the two ends be positioned at along its length, when being placed in described organism, from tapping in described organism or import liquid in described organism;
Information transceiver, it is when being placed in described organism, sends the described signal of telecommunication that described pressure sensing cell generates, and receive external demand signal to described organism outside; And
Device for storing liquid, it is connected with the opening of one end of described puncture tube, when being placed in described organism, for storing the liquid of deriving in described organism, and/or for storing the liquid imported in described organism.
According to an aspect of the embodiment of the present application, wherein, the tube chamber of described puncture tube holds one can by the seal wire freely plugged, and the hardness of described seal wire is greater than the hardness of described puncture tube.
According to an aspect of the embodiment of the present application, wherein, the material of described puncture tube is silica gel, and the material of described seal wire is titanium alloy.
According to an aspect of the embodiment of the present application, wherein, described information transceiver utilizes radio magnetic wave to send the described signal of telecommunication, and utilizes radio magnetic wave to receive described command signal.
According to an aspect of the embodiment of the present application, wherein, described device for storing liquid is the bag-shaped device of rectangle, and length is between 10 to 50 millimeters, and width is between 10 to 50 millimeters, and the outer wall thickness of this bag-shaped device is within 1 millimeter.
According to an aspect of the embodiment of the present application, wherein, the material of described device for storing liquid is silica gel.
The beneficial effect of the application is: can detect the pressure in organism in a convenient way, and without the need to carrying out repeatedly implant surgery; Further, the pressure in organism can be adjusted in time, and the medicine for the treatment of is imported to organism, improve effectiveness and the convenience for the treatment of.
With reference to explanation hereinafter and accompanying drawing, disclose in detail the particular implementation of the application, the principle specifying the application can adopted mode.Should be appreciated that, thus the embodiment of the application is not restricted in scope.In the spirit of claims and the scope of clause, the embodiment of the application comprises many changes, amendment and is equal to.
The feature described for a kind of embodiment and/or illustrate can use in one or more other embodiment in same or similar mode, combined with the feature in other embodiment, or substitutes the feature in other embodiment.
Should emphasize, term " comprises/comprises " existence referring to feature, one integral piece, step or assembly when using herein, but does not get rid of the existence or additional of one or more further feature, one integral piece, step or assembly.
Accompanying drawing explanation
Included accompanying drawing is used to provide the further understanding to the embodiment of the present application, which constitutes a part for description, for illustrating the embodiment of the application, and comes together to explain the principle of the application with text description.Apparently, the accompanying drawing in the following describes is only some embodiments of the application, for those of ordinary skill in the art, under the prerequisite not paying creative work, can also obtain other accompanying drawing according to these accompanying drawings.In the accompanying drawings:
Fig. 1 be embodiment 1 organism in a composition schematic diagram of pressure detecting and therapy equipment.
Detailed description of the invention
With reference to accompanying drawing, by description below, the aforementioned and further feature of the application will become obvious.In the specification and illustrated in the drawings, specifically disclose the particular implementation of the application, which show the some embodiments of the principle that wherein can adopt the application, will be appreciated that, the application is not limited to described embodiment, on the contrary, the application comprises the whole amendments fallen in the scope of claims, modification and equivalent.
Embodiment 1
The embodiment of the present application 1 provides pressure detecting and therapy equipment in a kind of organism.Fig. 1 be embodiment 1 organism in a composition schematic diagram of pressure detecting and therapy equipment, as shown in Figure 1, in this organism, pressure detecting and therapy equipment 100 comprise pressure sensing cell 101, puncture tube 102, information transceiver 103 and device for storing liquid 104.
Wherein, pressure sensing cell 101, when being placed in organism, detects the pressure in organism, to generate the signal of telecommunication corresponding with described pressure; Puncture tube 102 has the opening at the two ends be positioned at along its length, when being placed in organism, for importing liquid from tapping in organism or in described organism; Information transceiver, it is when being placed in organism, sends the described signal of telecommunication corresponding with pressure that described pressure sensing cell 101 generates, and receive external demand signal to organism outside; Device for storing liquid 104 is connected with the opening of one end of described puncture tube, when being placed in described organism, for storing the liquid of deriving in described organism, and/or for storing the liquid imported in described organism.
In the present embodiment, can by Minimally Invasive Surgery by pressure detecting in this organism and therapy equipment 100 implantable bioartificial body, or to carry out in process in passing in implanted organism in other operation, when this device 100 is placed in organism, can be used in detecting the pressure in organism, and organism is treated.
In the present embodiment, when pressure detecting in this organism and therapy equipment 100 are placed in organism, the pressure in organism can be detected exactly by pressure sensing cell 101, and by information transceiver 103, pressure detecting signal is exported, thus, detect rapidly and exactly the pressure in organism, and carry out signal transmission easily.
In the present embodiment, when in organism during hypertonia, from device for storing liquid 104, the liquid in organism can be exported to device for storing liquid 104, and be discharged to external via drainage needle from device for storing liquid 104, thus, in organism and external between device for storing liquid 104 play the effect of barrier, avoid in organism and be directly communicated with the external world, thus, reduce the infection risk in organism, and can to ensure in this organism that pressure detecting and therapy equipment 100 can be put for a long time to stay in vivo, so without the need to carrying out repeatedly implant surgery.
In the present embodiment, when needs are treated organism, device for storing liquid 104 can be injected into from outside by pharmaceutical liquid, thus, pharmaceutical liquid can be directed in organism via puncture tube, reach the effect to applying medicine in organism, thereby, it is possible in time and effectively give treatment to organism.
In the present embodiment, when without the need to using this device, the situation such as after if such as patient fully recovers, this device 100 can be put stays in patient body, without the need to taking out, only need send out code to information transceiver 103, this device 100 can be closed, again carry out monitoring and treating if need after patient, then only need send open command to information transceiver 103 and just can use again to activate this device 100, mobility and operating characteristics are very high.
As can be seen here, by pressure detecting and therapy equipment in the organism of the present embodiment, can detect the pressure in organism in a convenient way; Further, the pressure in organism can be adjusted in time, and the medicine for the treatment of is imported to organism, improve effectiveness and the convenience for the treatment of.
In the present embodiment, pressure sensing cell 101 such as can comprise pressure transducer, and this pressure transducer can be such as differential pressure piezoresistive pressure sensor, but the present embodiment is not limited thereto, and pressure transducer also can be other type.
In the present embodiment, the tube chamber of puncture tube 102 can hold a seal wire (scheming not shown), this seal wire can freely be plugged in this tube chamber, and, the hardness of this seal wire can be greater than the hardness of this puncture tube 102, such as, the material of this puncture tube 102 can be silica gel etc., and the material of this seal wire can be titanium alloy etc.In the present embodiment, by the process in this puncture tube implantable bioartificial body, seal wire can be inserted in this puncture tube 102, thus, improve the intensity of this puncture tube 102, be convenient to implant; After implantation completes, this seal wire can be extracted from the tube chamber of puncture tube 102, can successfully guide liquid to make this tube chamber.
In the present embodiment, the pressure signal that information transceiver 103 can utilize radio magnetic wave to generate to send pressure sensing cell 101, thereby, it is possible to carry out signal transmission easily.In the present embodiment, this information transceiver 103 can also utilize radio magnetic wave to receive the described command signal from outside, and such as, this command signal can be instruction etc. that is automatic by setting-up time interval, intracranial pressure continuously.In the present embodiment, this radio magnetic wave can be such as Bluetooth signal etc., but the present embodiment is not limited to this, can also be other radio magnetic wave.
In addition, in the present embodiment, information transceiver 103 can be connected with pressure sensing cell 101 by connecting dotted line, thus receives the described signal of telecommunication of pressure sensing cell 101 generation, and transmits control signal to pressure sensing cell 101.Certainly, the present embodiment is not limited to this, also can be communicated by radio magnetic wave signal between information transceiver 103 and pressure sensing cell 101.
In the present embodiment, this device for storing liquid 104 can be arranged in organism, such as, this device for storing liquid 104 can be the bag-shaped device of rectangle, length is between 10 to 50 millimeters, and width is between 10-50 millimeter, and the outer wall thickness of this bag-shaped device can within 1 millimeter.This device for storing liquid 104 can adopt the one-tenth of the good silicon materials of biocompatibility, such as silica gel etc., this material has good sealing property and restores performance, thus, at this device for storing liquid of use scalp acupuncture puncture to draw liquid or after injecting liquid, this device for storing liquid can recover to seal automatically.
In the organism of the present embodiment, pressure detecting and therapy equipment can be used in detection and the treatment of intracranial pressure, such as, can measure in real time intracranial pressure, also there is the effect of drainage of cerebrospinal fluid and ventricles of the brain administration simultaneously, emergency aid and treatment can be carried out to the complication such as the hydrocephalus of postoperative burst and intracranial infection and associated disease.In the present embodiment, in this organism, pressure detecting and therapy equipment can not only be used for intracranial pressure and detect and the treatment of intracranial disease, also may be used for pressure detecting and the treatment at other positions in organism, such as, may be used for the pressure detecting to vascular venous or tremulous pulse and treatment.
Below, for the detection of intracranial pressure with treatment for example, the using method of pressure detecting and therapy equipment 100 in the organism of the application is described.
(1) device 100 of the present invention is implanted: can being implanted by device 100 through a Minimally Invasive Surgery, also can complete in passing when doing other craniocerebral operations.Such as, seal wire can be inserted into the tube chamber of puncture tube 102, and puncture tube 102 and pressure sensing cell 101 are penetrated into Intraventricular, make the one end open of pressure sensing cell 101 and puncture tube 102 impregnated in cerebrospinal fluid, then the seal wire in the tube chamber of puncture tube 102 is pulled out; Further, under the device for storing liquid 104 be connected with puncture tube other end opening and the information transceiver device 103 be connected with sensor can be placed in scalp layer.
(2) measurement of intracranial pressure (ICP): during measurement, only need send open command by external programmer to information transceiver 103, according to the requirement of this open command ICP by pressure transducer Automatic continuous, repeated measure patient; When this device 100 closed by needs, out code can be sent to information transceiver 103, this device 100 can be closed.
(3) treatment of intracranial disease: on the one hand, when monitoring intracranial pressure display Intraventricular pressure increases, medical personnel's available head sword-shaped needle, puncture the device for storing liquid 104 under scalp from scalp, draw cerebrospinal fluid, thus reduce Intraventricular pressure, play the therapeutical effect of drain; On the other hand, because human brain exists blood brain barrier usually, many medicines do not reach valid density at intracranial, for the serious intracranial infection of some refractory, need directly the infusion of medicine ventricles of the brain to be carried out topical therapeutic, in addition, there is blood clot in part traumatic patient Intraventricular, the pressure sensitive probe of meeting retaining pressure detecting unit, cause the inaccurate of monitoring intracranial pressure, therefore need to rinse probe, now just can by the input such as medicine or normal saline device for storing liquid, the direct arrival ventricles of the brain, thus reach treatment or rinse the effect of popping one's head in.
Seen from the above description, by when in the organism of the embodiment of the present application, pressure detecting and therapy equipment are used for intracranial pressure test-and-treat, be that apparatus of the present invention also have certain therapeutical effect concurrently while having monitoring effect with the difference of other monitoring intracranial pressure device, namely, by the device for storing liquid 104 implanted under scalp, healthcare givers can treat easily: if find that patient's intracranial pressure is too high by measuring, drawn by cerebrospinal fluid by device for storing liquid, if the intracranial infection that postoperative appearance is serious, then anti-infectives directly can be inputted device for storing liquid, the through ventricles of the brain, carry out effective treatment, for patient strives for more treatment time, also can reduce patient opens the probability of cranium and infected risk again simultaneously.
Pressure detecting and therapy equipment in the organism of the embodiment of the present application being used for the pressure detecting at other position in organism with when treating, also similar effect can be reached.
More than in conjunction with concrete embodiment to present application has been description, but it will be apparent to those skilled in the art that these descriptions are all exemplary, is not the restriction to the application's protection domain.Those skilled in the art can make various variants and modifications according to the spirit of the application and principle to the application, and these variants and modifications are also in the scope of the application.
Claims (6)
1. pressure detecting and a therapy equipment in organism, can be placed in organism, and for detecting the pressure in organism, and treating organism, it is characterized in that, this device comprises:
Pressure sensing cell, it is when being placed in described organism, detects the pressure in organism, to generate the signal of telecommunication corresponding with described pressure;
Puncture tube, it has the opening at the two ends be positioned at along its length, when being placed in described organism, from tapping in described organism or import liquid in described organism;
Information transceiver, it is when being placed in described organism, sends the described signal of telecommunication that described pressure sensing cell generates, and receive external demand signal to described organism outside; And
Device for storing liquid, it is connected with the opening of one end of described puncture tube, when being placed in described organism, for storing the liquid of deriving in described organism, and/or for storing the liquid imported in described organism.
2. pressure detecting and therapy equipment in organism as claimed in claim 1, is characterized in that,
The tube chamber of described puncture tube holds one can by the seal wire freely plugged, and the hardness of described seal wire is greater than the hardness of described puncture tube.
3. pressure detecting and therapy equipment in organism as claimed in claim 2, is characterized in that,
The material of described puncture tube is silica gel, and the material of described seal wire is titanium alloy.
4. pressure detecting and therapy equipment in organism as claimed in claim 1, is characterized in that,
Described information transceiver utilizes radio magnetic wave to send the described signal of telecommunication, and utilizes radio magnetic wave to receive described command signal.
5. pressure detecting and therapy equipment in organism as claimed in claim 1, is characterized in that,
Described device for storing liquid is the bag-shaped device of rectangle, and length is between 10 to 50 millimeters, and width is between 10 to 50 millimeters, and the outer wall thickness of this bag-shaped device is within 1 millimeter.
6. pressure detecting and therapy equipment in organism as claimed in claim 1, is characterized in that,
The material of described device for storing liquid is silica gel.
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| CN201510231070.2A CN104825150A (en) | 2015-05-07 | 2015-05-07 | Intracranial disease monitoring and treating device |
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| CN105286847A (en) * | 2015-10-30 | 2016-02-03 | 哈尔滨工业大学 | Intracranial pressure detecting system and implantation method of intracranial pressure detecting device |
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| CN105286847A (en) * | 2015-10-30 | 2016-02-03 | 哈尔滨工业大学 | Intracranial pressure detecting system and implantation method of intracranial pressure detecting device |
| CN110191738A (en) * | 2016-11-16 | 2019-08-30 | 拉莫特特拉维夫大学有限公司 | Encephalic volume for cerebral blood flow adapts to device |
| CN110191738B (en) * | 2016-11-16 | 2021-11-02 | 拉莫特特拉维夫大学有限公司 | Intracranial volume adapter for cerebral blood flow |
| US11565091B2 (en) | 2016-11-16 | 2023-01-31 | Ramot At Tel-Aviv University Ltd. | Intracranial volume adaptor for cerebral blood flow |
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