CN104793001A - Detection strip automation analysis system capable of executing preprocessing and analyses of detection strips - Google Patents

Detection strip automation analysis system capable of executing preprocessing and analyses of detection strips Download PDF

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Publication number
CN104793001A
CN104793001A CN201410197911.8A CN201410197911A CN104793001A CN 104793001 A CN104793001 A CN 104793001A CN 201410197911 A CN201410197911 A CN 201410197911A CN 104793001 A CN104793001 A CN 104793001A
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CN
China
Prior art keywords
detector bar
assembly
mentioned
reagent
automatic analysis
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Pending
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CN201410197911.8A
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Chinese (zh)
Inventor
白文哲
辛兴善
李承权
朴丙哲
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K Mac Inc
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K Mac Inc
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N2001/002Devices for supplying or distributing samples to an analysing apparatus

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The invention relates to a detection strip automation analysis system, which can automatically executing preprocessing and analyses of detection strips in one equipment, capable of executing preprocessing and the analyses of the detection strips. The detection strip automation analysis system comprises a detection strip assembly forming a plurality of detection strips storing analysis objects, a reagent dispensing assembly moving at the upper part of the detection strip assembly in the left-right direction and dispensing a reagent to the detection strips of the detection strip assembly, a preprocessing reaction assembly enabling the detection strip assembly to vibrate so that the analysis objects in the detection strips of the detection strip assembly to react with the reagent, a residual reagent suction assembly sucking the reagent left on the detection strips of the detection strip assembly after the analysis objects react with the reagent, a detection strip drying assembly enabling the internal of the detection strips, from which the reagent is removed, of the detection strip assembly, and an analysis assembly moving at the upper part of the detection assembly in the left-right direction and analyzing the detection strips of the detection strip assembly.

Description

The pre-service of detector bar and the detector bar automatic analysis system of analysis can be performed
Technical field
The present invention relates to a kind of detector bar analytical technology, relate in more detail a kind of can one equipment in automatically perform the pre-service of detector bar and the detector bar automatic analysis system of analysis.
Background technology
Detector bar analysis is the method utilized when carrying out immunodiagnosis or molecular diagnosis.
If want to carry out detector bar analysis, just needing the pre-service equipment for making detector bar develop the color, also needing the analytical equipment for analysis result.
In the past, equipping utilizing pre-service after pre-service is carried out to detector bar, analytical equipment will be moved on to through pretreated detector bar, and confirming result.That is, when in the past, pre-service equipment is individually separated with analytical equipment.
Therefore, when in the past, if want to carry out detector bar analysis, just need a lot of time and manpower.
Existing document related to the present invention has disclosed detector bar and analytical equipment in No. 10-2011-0134017th, Korean Patent Laid (on Dec 14th, 2011 is open).
Summary of the invention
The object of the invention is to, being provided as utilizing detector bar analytic approach can automatically perform the pre-service of detector bar and the detector bar automatic analysis system of analysis in an equipment to the system performing immunodiagnosis or molecular diagnosis.
Being a kind of detector bar automatic analysis system for reaching the embodiments of the invention of an above-mentioned purpose, it is characterized in that, comprise: detector bar assembly, being formed with multiple detector bar, storing material for testing at each detector bar; Reagent dispensing assembly, moves in left-right direction on the top of above-mentioned detector bar assembly, and to each detector bar dispensing reagent of above-mentioned detector bar assembly; Pretreatment reaction assembly, makes above-mentioned detector bar assembly vibrate, and reacts to make the material for testing in each detector bar of above-mentioned detector bar assembly and reagent; Remaining reagent suction assembly, after material for testing and reagent react, sucks the reagent remaining in each detector bar of above-mentioned detector bar assembly; Detector bar dry component, makes the inside of each detector bar of the detector bar assembly eliminating mentioned reagent dry; And analytic unit, move in left-right direction on the top of above-mentioned detector bar assembly, and analyze each detector bar of above-mentioned detector bar assembly.
Now, mentioned reagent dispensing assembly can be positioned at left and right directions side, and above-mentioned analytic unit can be positioned at left and right directions opposite side.In this case, mentioned reagent dispensing assembly and above-mentioned analytic unit can move in left-right direction in same transfer track.
Further, above-mentioned remaining reagent suction assembly and detector bar dry component can move in left-right direction on the top of above-mentioned detector bar assembly.
Further, above-mentioned pretreatment reaction assembly can make above-mentioned detector bar assembly vibrate.
Further, above-mentioned pretreatment reaction assembly can make above-mentioned detector bar assembly carry out tilting action.In this case, preferably, when above-mentioned detector bar assembly tilts, with the bottom surface of detector bar assembly for benchmark, the angle of inclination is 4 ° ~ 8.5 °.
Further, above-mentioned reaction component can combine with the bottom of above-mentioned detector bar assembly.
Further, mentioned reagent dispensing assembly and remaining reagent suction assembly can move with the state of mutually adhering to simultaneously.
Further, above-mentioned detector bar dry component can comprise: well heater, for adding hot-air; And pressure fan, for carrying heated air.
Further, above-mentioned detector bar dry component can comprise line with heating function dryer or lamp dryer.
Further, above-mentioned detector bar dry component can combine with mentioned reagent dispensing assembly or analytic unit with detachable form.In this case, above-mentioned detector bar dry component can combine with mentioned reagent dispensing assembly or analytic unit in magnet mode.
Further, above-mentioned remaining reagent suction assembly and detector bar dry component can drive simultaneously, perform the suction of remaining reagent and the drying of detector bar simultaneously.
Further, above-mentioned analytic unit can comprise imageing sensor, and above-mentioned imageing sensor is taken each detector bar of above-mentioned detector bar assembly and transmitted to anacom.In this case, above-mentioned analytic unit can also comprise luminaire, and above-mentioned imageing sensor can be taken by above-mentioned luminaire.
According to detector bar automatic analysis system of the present invention, the pre-service of detector bar can not only be performed successively by reagent dispensing assembly, reaction component, detector bar dry component and remaining reagent suction assembly, analytic unit execution analysis can also be passed through after detector bar pre-service, thus all detector bar analytic processes can be automatically performed in an equipment.
Further, detector bar automatic analysis system of the present invention can pass through detector bar dry component and remaining reagent suction assembly, shortens pretreatment time to greatest extent, thus can the at the appointed time more sample of inner analysis.
Accompanying drawing explanation
Fig. 1 schematically illustrates the detector bar automatic analysis system of embodiments of the invention.
Fig. 2 shows in detail the detector bar dry component of Fig. 1.
Fig. 3 shows in detail the analytic unit of Fig. 1.
The explanation of Reference numeral
110: detector bar assembly 111: detector bar
120: reagent dispensing assembly 130: pretreatment reaction assembly
140: remaining reagent suction assembly 150: detector bar dry component
160: analytic unit 170: transfer track
151: well heater 152: pressure fan
161: imageing sensor 162: luminaire
Embodiment
The method that the embodiment described in detail with reference to accompanying drawing can make advantage of the present invention and feature and reach these advantages and feature definitely.But; the present invention is not by the restriction of following the disclosed embodiments; can implement in mutually different various mode; the present embodiment is only for making disclosure of the present invention more complete; general technical staff of the technical field of the invention can be made more intactly to understand the category of invention, and the present invention only defines according to the claimed scope of invention.In instructions full text, identical Reference numeral represents identical textural element.
Below, with reference to accompanying drawing, the detector bar automatic analysis system of embodiments of the invention is described.
Fig. 1 schematically illustrates the detector bar automatic analysis system of embodiments of the invention.
With reference to Fig. 1, detector bar automatic analysis system of the present invention comprises detector bar assembly 110, reagent dispensing assembly 120, pretreatment reaction assembly 130, remaining reagent suction assembly 140, detector bar dry component 150 and analytic unit 160.Said modules can be controlled by Control Component (not shown) separately.
Multiple detector bar 111 is formed at detector bar assembly 110.Store as material for testing such as blood at each detector bar.
Reagent dispensing assembly 120 moves in left-right direction on the top of detector bar assembly 110, and to each detector bar 111 dispensing reagent (antigenic agents such as, reacted with the antibody of blood) of detector bar assembly 110.Such as, when detector bar assembly comprises 10 detector bars, reagent dispensing assembly moves to the top of first detector bar and dispensing reagent from the initial position left side of shell (the Fig. 1 for), move to the top of second detector bar afterwards and dispensing reagent, finally move to the top of the tenth detector bar and dispensing reagent.Afterwards, reagent dispensing assembly moves to initial position.
A point fluence for reagent in reagent dispensing assembly 120 is delivered to Control Component, can carry out additional dispensing or pretreatment reaction etc. at Control Component.
The reaction of material for testing in each detector bar 111 of detector bar assembly 110 and reagent induced by pretreatment reaction assembly 130.
For this reason, pretreatment reaction assembly 130 can make detector bar assembly 110 vibrate.Along with pretreatment reaction assembly 130 vibrates (such as, fore-and-aft direction vibrates), detector bar assembly 110 also can vibrate thereupon, and the material for testing in detector bar 111 and reagent can be induced thus to react.
Further, pretreatment reaction assembly 130 can make detector bar assembly 110 repeatedly carry out above tilting action once or twice.Now, when detector bar assembly tilts, with the bottom surface of detector bar assembly for benchmark, the angle of inclination is preferably 4 ° ~ 8.5 °.When angle when detector bar assembly tilts is less than 4 °, the pretreatment reaction time is likely elongated, and when the angle when detector bar assembly tilts is greater than 8.5 °, reagent etc. likely overflow.
Above-mentioned pretreatment reaction assembly 130 can combine with the bottom of detector bar assembly 110.
At material for testing and reagent after each detector bar 111 reacts, remaining reagent suction assembly 140 sucks the reagent remaining in each detector bar of detector bar assembly 110.
If reagent is sucked by remaining reagent suction assembly 140, then likely only remain the material for testing of reaction end at each detector bar 111.Therefore, analytic unit 160 described later can carry out detector bar analysis.
Remaining reagent suction assembly 140 can suck the remaining reagent in each detector bar 111 in the lump, but in this case, causes the size of remaining reagent suction assembly to increase.Therefore, preferably, remaining reagent suction assembly 140 moves in left-right direction, and sucks the remaining reagent in each detector bar successively.In this case, example as shown in Figure 1, remaining reagent suction assembly 140 together can configure with reagent dispensing assembly 120.
On the other hand, example as shown in Figure 1, reagent dispensing assembly 120 and remaining reagent suction assembly 140 can be the state of mutually adhering to, and in this case, reagent dispensing assembly 120 and remaining reagent suction assembly 140 can move simultaneously.
Detector bar dry component 150 makes material for testing and reagent react and eliminates the inside drying of each detector bar 111 of the detector bar assembly 110 of remaining reagent.By the drying of detector bar 111, can analysis time be shortened, and improve accuracy.
For this reason, detector bar dry component 150 can comprise: well heater 151, for adding hot-air; And pressure fan 152, for carrying heated air.Further, detector bar dry component 150 can comprise and utilizes line with heating function to heat line with heating function dryer or the lamp dryer of detector bar.
Further, detector bar dry component 150 can carry out drying in each detector bar in the lump, but in this case, the size of detector bar dry component 150 can be caused to increase.Therefore, preferably, detector bar dry component 150 moves in left-right direction, and carries out drying to each detector bar successively.
Further, detector bar dry component 150 can combine with reagent dispensing assembly 120 or analytic unit 160.Now, detector bar dry component 150 can combine with reagent dispensing assembly 120 or analytic unit 160 with detachable form, thus detector bar dry component 150 can be transferred as required.In order to easily perform the mounting or dismounting of detector bar dry component 150, detector bar dry component 150 can combine with reagent dispensing assembly 120 or analytic unit 160 in magnet mode.
Further, in detector bar automatic analysis system of the present invention, remaining reagent suction assembly and detector bar dry component can drive simultaneously, perform the suction of remaining reagent and the drying of detector bar simultaneously.In this case, detector bar pretreatment time can shorten more.
Analytic unit 160 moves in left-right direction on the top of detector bar assembly 110, and analyzes each detector bar 111 of the detector bar assembly 110 that pre-service terminates.Such as, if material for testing and reagent react and makes the color of material for testing change, then analytic unit 160 is by analyzing this situation, derives the state of material for testing.
More specifically, analytic unit 160 can comprise imageing sensor 161, and each detector bar of above-mentioned imageing sensor 161 shot detection bar assembly 110 also transmits to anacom.
Further, above-mentioned analytic unit 160 can also comprise luminaire 162, and local not fully in illumination, imageing sensor can be taken by above-mentioned luminaire 162.As luminaire 162, light emitting diode (LED) ligthing paraphernalia can be utilized, the applicable luminaire of each imageing sensor or plural luminaire.
The mode that luminaire 162 can become roughly 90 ° with illumination angle relative to the surface of detector bar configures, and the mode that also can become roughly 45 ° ~ 60 ° with illumination angle relative to the surface of detector bar configures.The former when, have the advantage that can obtain the brightest image, when the latter, having can the advantage of inhibitory reflex image fault.
On the other hand, example as shown in Figure 1, reagent dispensing assembly can be positioned at left and right directions side, and analytic unit 160 can be positioned at left and right directions opposite side.In this case, reagent dispensing assembly 120 and analytic unit 170 can move in left-right direction in same transfer track 170, thus can the size of reduction system, and are simplified by equipment.
As mentioned above, detector bar automatic analysis system of the present invention can not only perform the pre-service of detector bar successively by various assembly, can also pass through analytic unit execution analysis after detector bar pre-service.Therefore, detector bar automatic analysis system of the present invention can automatically perform all detector bar analytic processes in an equipment.
General technical staff of the technical field of the invention above, is illustrated centered by embodiments of the invention, as long as but just can implement various change or distortion.Only otherwise depart from the scope of technological thought provided by the invention, this change and distortion belong to the present invention.Therefore, scope of the present invention should judge according to the following described claimed scope of invention.

Claims (16)

1. a detector bar automatic analysis system, is characterized in that, comprising:
Detector bar assembly, is formed with multiple detector bar, stores material for testing at each detector bar;
Reagent dispensing assembly, moves in left-right direction on the top of above-mentioned detector bar assembly, and to each detector bar dispensing reagent of above-mentioned detector bar assembly;
Pretreatment reaction assembly, induces the material for testing in each detector bar of above-mentioned detector bar assembly and reagent to react;
Remaining reagent suction assembly, after material for testing and reagent react, sucks the reagent remaining in each detector bar of above-mentioned detector bar assembly;
Detector bar dry component, makes the inside of each detector bar of the detector bar assembly eliminating mentioned reagent dry; And
Analytic unit, moves in left-right direction on the top of above-mentioned detector bar assembly, and analyzes each detector bar of above-mentioned detector bar assembly.
2. detector bar automatic analysis system according to claim 1, is characterized in that, mentioned reagent dispensing assembly is positioned at left and right directions side, and above-mentioned analytic unit is positioned at left and right directions opposite side.
3. detector bar automatic analysis system according to claim 2, is characterized in that, mentioned reagent dispensing assembly and above-mentioned analytic unit move in left-right direction in same transfer track.
4. detector bar automatic analysis system according to claim 1, is characterized in that, above-mentioned remaining reagent suction assembly and detector bar dry component move in left-right direction on the top of above-mentioned detector bar assembly.
5. detector bar automatic analysis system according to claim 1, is characterized in that, above-mentioned pretreatment reaction assembly makes above-mentioned detector bar assembly vibrate.
6. detector bar automatic analysis system according to claim 1, is characterized in that, above-mentioned pretreatment reaction assembly makes above-mentioned detector bar assembly carry out tilting action.
7. detector bar automatic analysis system according to claim 6, is characterized in that, when above-mentioned detector bar assembly tilts, with the bottom surface of detector bar assembly for benchmark, the angle of inclination is 4 ° ~ 8.5 °.
8. detector bar automatic analysis system according to claim 1, is characterized in that, above-mentioned pretreatment reaction assembly combines with the bottom of above-mentioned detector bar assembly.
9. detector bar automatic analysis system according to claim 1, is characterized in that, mentioned reagent dispensing assembly and remaining reagent suction assembly move with the state of mutually adhering to simultaneously.
10. detector bar automatic analysis system according to claim 1, is characterized in that, above-mentioned detector bar dry component comprises:
Well heater, for adding hot-air; And
Pressure fan, for carrying heated air.
11. detector bar automatic analysis systems according to claim 1, is characterized in that, above-mentioned detector bar dry component comprises line with heating function dryer or lamp dryer.
12. detector bar automatic analysis systems according to claim 1, is characterized in that, above-mentioned detector bar dry component combines with mentioned reagent dispensing assembly or analytic unit with the form that can install and remove.
13. detector bar automatic analysis systems according to claim 12, is characterized in that, above-mentioned detector bar dry component combines with mentioned reagent dispensing assembly or analytic unit in magnet mode.
14. detector bar automatic analysis systems according to claim 1, is characterized in that, above-mentioned remaining reagent suction assembly and detector bar dry component drive simultaneously, perform the suction of remaining reagent and the drying of detector bar simultaneously.
15. detector bar automatic analysis systems according to claim 1, it is characterized in that, above-mentioned analytic unit comprises imageing sensor, and above-mentioned imageing sensor is taken each detector bar of above-mentioned detector bar assembly and transmitted to anacom.
16. detector bar automatic analysis systems according to claim 15, it is characterized in that, above-mentioned analytic unit also comprises luminaire, and above-mentioned imageing sensor can be taken by above-mentioned luminaire.
CN201410197911.8A 2014-01-17 2014-05-12 Detection strip automation analysis system capable of executing preprocessing and analyses of detection strips Pending CN104793001A (en)

Applications Claiming Priority (2)

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KR1020140006301A KR102175186B1 (en) 2014-01-17 2014-01-17 Auto analysis system for strip
KR10-2014-0006301 2014-01-17

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KR102241251B1 (en) * 2019-07-26 2021-04-16 주식회사 수젠텍 Multiplexing blot assay automation system

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Application publication date: 20150722