CN104688235B - Mapping micro guide wire and manufacturing method thereof - Google Patents

Mapping micro guide wire and manufacturing method thereof Download PDF

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Publication number
CN104688235B
CN104688235B CN201510112168.6A CN201510112168A CN104688235B CN 104688235 B CN104688235 B CN 104688235B CN 201510112168 A CN201510112168 A CN 201510112168A CN 104688235 B CN104688235 B CN 104688235B
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Prior art keywords
wire
micro
core filaments
scale strip
preparation
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CN201510112168.6A
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CN104688235A (en
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仇汉诚
成正辉
匡华
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Beijing Kelaiwen Technology Consulting Co ltd
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HUNAN AIPUTE MEDICAL EQUIPMENT CO Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/103Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/107Measuring physical dimensions, e.g. size of the entire body or parts thereof
    • A61B5/1076Measuring physical dimensions, e.g. size of the entire body or parts thereof for measuring dimensions inside body cavities, e.g. using catheters

Abstract

The invention belongs to the field of medical apparatuses and instruments, and particularly relates to a mapping micro guide wire and a manufacturing method thereof. The mapping micro guide wire comprises a conveying core wire. A plurality of scale strips are arranged on the conveying core wire in the length direction of the conveying core wire. The scale strips are developed under irradiation of X rays. The size of a vasculopathy part can be accurately measured through the mapping micro guide wire under the irradiation of X rays, and therefore the success rate of follow-up operations is increased, the operation process is simplified as much as possible, operation expenses are reduced to a great extent, and burdens on patients are reduced.

Description

A kind of mapping micro-wire and preparation method thereof
Technical field
The invention belongs to medical instruments field, more particularly to a kind of mapping micro-wire and preparation method thereof.
Background technology
Because ductus arteriosus wall local birth defect and cavity pressure increase, ductus arteriosus wall is gradually thinning and abnormal bulging, Clinically it is referred to as aneurysm.Atherosclerosiss can cause angiostenosiss, and angiostenosiss are cause ischemic diseasess one Major reason and risk factor.For aneurysm, it is general using Ink vessel transfusing Coil embolization technology or stent inserting art come Treatment, and angiostenosiss, then by the way that a support is placed on into narrow positions, to reach the purpose for the treatment of.
No matter aneurysm or angiostenosiss, the preoperative size that be required for determine lesion portion, further according to size choosing are treated Select the suitable turn of specification and support.Carry out the determination of vascular lesion spot size mainly by Angiography at present, but It is to be difficult to precisely judge the actual size of diseased region merely by angiography, especially for the lesion of tortuous blood vessel Position.
The content of the invention
In view of this, it is an object of the invention to provide a kind of mapping micro-wire and preparation method thereof, what the present invention was provided Mapping micro-wire can be accurately measured to the size at vascular lesion position.
The invention provides a kind of mapping micro-wire, including conveying core filaments, set along its length in the conveying core filaments It is equipped with several scale strips;
The scale strip develops under x-ray bombardment.
Preferably, the material of the scale strip is platinum, platinum alloy, gold, nickel alloy, titanium alloy or rustless steel.
Preferably, the scale strip is the raised item arranged along the excircle of the conveying core filaments.
Preferably, the width of the scale strip is 0.2~1mm.
Preferably, the spacing of the adjacent scale strip is 0.5~3mm.
Preferably, the spacing of the adjacent scale strip is equal.
Preferably, the micro-wire also includes conductive filament head, and the conductive filament head is connected with the conveying core filaments.
Preferably, the material of the conductive filament head is platinum, platinum alloy, tungsten, billon or rustless steel.
The invention provides a kind of preparation method of mapping micro-wire, comprises the following steps:
Several scale strips are welded in conveying core filaments along the length direction that micro-wire conveys core filaments, obtain that mapping is micro- to be led Silk;
The scale strip develops under x-ray bombardment.
Preferably, the mode of the welding is soldering or laser welding.
Compared with prior art, the invention provides a kind of mapping micro-wire and preparation method thereof.The mark that the present invention is provided Micrometer seal wire includes conveying core filaments, and in the conveying core filaments several scale strips are provided with along its length;The scale strip Develop under x-ray bombardment.The mapping micro-wire that the present invention is provided can enter under x-ray bombardment to the size at vascular lesion position Row is accurately measured, and has so both improve the success rate of subsequent procedures, operation process is simplified as far as possible, and also high degree reduces handss Art expense, mitigates patient burden.
Description of the drawings
In order to be illustrated more clearly that the embodiment of the present invention or technical scheme of the prior art, below will be to embodiment or existing The accompanying drawing to be used needed for having technology description is briefly described, it should be apparent that, drawings in the following description are only this Inventive embodiment, for those of ordinary skill in the art, on the premise of not paying creative work, can be with basis The accompanying drawing of offer obtains other accompanying drawings.
Fig. 1 is mapping micro-wire structural representation provided in an embodiment of the present invention;
Fig. 2 is that mapping micro-wire provided in an embodiment of the present invention measures aneurysmal use schematic diagram;
Fig. 3 is the use schematic diagram that mapping micro-wire provided in an embodiment of the present invention measures blood vessel.
Specific embodiment
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is carried out clear, complete Site preparation is described, it is clear that described embodiment is only a part of embodiment of the invention, rather than the embodiment of whole.It is based on Embodiment in the present invention, it is every other that those of ordinary skill in the art are obtained under the premise of creative work is not made Embodiment, belongs to the scope of protection of the invention.
The invention provides a kind of mapping micro-wire, including conveying core filaments, set along its length in the conveying core filaments It is equipped with several scale strips;
The scale strip develops under x-ray bombardment.
Referring to Fig. 1, Fig. 1 is mapping micro-wire structural representation provided in an embodiment of the present invention, wherein, 1 is conveying core filaments, 2 is several scale strips, and 3 is conductive filament head.
The mapping micro-wire that the present invention is provided includes conveying core filaments 1, is provided with along its length in conveying core filaments 1 some Individual scale strip 2.In one embodiment that the present invention is provided, the material for conveying core filaments 1 is Nitinol and/or rustless steel. In one embodiment that the present invention is provided, a diameter of 0.20~1.0mm of core filaments 1 is conveyed.In the enforcement that the present invention is provided In example, the length for conveying core filaments 1 is 130~300cm.In one embodiment that the present invention is provided, the surface for conveying core filaments 1 applies It is covered with hydrophilic layer or hydrophobic layer.In one embodiment that the present invention is provided, the material of the hydrophilic layer is polyvinylpyrrolidine Ketone, the material of the hydrophobic layer is politef.In one embodiment that the present invention is provided, the hydrophilic layer or hydrophobic layer Thickness be 0.006~0.025mm.
In the present invention, scale strip 2 develops under x-ray bombardment.In the embodiment that the present invention is provided, scale strip 2 Material is platinum, platinum alloy, gold, nickel alloy, titanium alloy or rustless steel.In one embodiment that the present invention is provided, scale strip 2 Width is 0.2~1.0mm.In one embodiment that the present invention is provided, length and the conveying excircle of core filaments 1 of scale strip 2 Girth is equal.In one embodiment that the present invention is provided, the number of some scale strips 2 is 6~12.There is provided in the present invention In one embodiment, the spacing of adjacent scale strip 2 is 0.5~3mm;In another embodiment that the present invention is provided, adjacent quarter The spacing of degree bar 2 is equal.In one embodiment that the present invention is provided, scale strip 2 is the excircle setting along conveying core filaments 1 Raised item.In one embodiment that the present invention is provided, scale strip 2 is connected with conveying core filaments 1 by way of welding.
In one embodiment that the present invention is provided, mapping micro-wire also includes conductive filament head 3, conductive filament head 3 and conveying core filaments 1 It is connected.In one embodiment that the present invention is provided, the conductive filament head connection end for conveying core filaments 1 is designed to the taper of Diameter Gradual Change, For improving the compliance of conductive filament head 3.In one embodiment that the present invention is provided, the material of conductive filament head 3 be platinum, platinum alloy, Tungsten, billon or rustless steel.In one embodiment that the present invention is provided, conductive filament head 3 is turned to by tinsel, helically spring Shape.In one embodiment that the present invention is provided, a diameter of 0.05~0.25mm wiry.One provided in the present invention Helically in the embodiment of spring-like, external diameter of the conductive filament head 3 along the section of its axis is 0.20~1.0mm to individual conductive filament head 3.At this Helically in the embodiment of spring-like, conductive filament head 3 is 5~100mm along the length of its axis to the conductive filament head 3 that invention is provided.
In the present invention, mapping micro-wire is delivered to into target blood, micro-wire scale strip is across target blood lesion Point, target blood diseased region is gone out by the width of micro-wire high scale bar and the distance measurement of scale strip under x-ray bombardment Size.
The mapping micro-wire that the present invention is provided is provided with the scale strip developed under x-ray bombardment in conveying core filaments, in X The size at vascular lesion position, such as aneurysm diameter, aneurysm neck breadth and angiostenosiss segment length can be accurately measured under roentgenization Degree etc., is particularly well-suited to the measurement of tortuous vascular lesion spot size.In the present invention, to the accurate of vascular lesion spot size Measurement is conducive to the suitable turn of subsequently selected specification or support to carry out the treatment at vascular lesion position, is easy to operation technique, The success rate of operation is improved, surgery cost is reduced.Led using micro- in the particularly suitable Rhizoma Atractylodis Macrocephalae of mapping micro-wire that the present invention is provided Situation of the pipe (such as Plus conduits), mapping micro-wire is transported at target lesion along microtubular and measures.
The invention provides a kind of preparation method of mapping micro-wire, comprises the following steps:
Several scale strips are welded in conveying core filaments along the length direction that micro-wire conveys core filaments, obtain that mapping is micro- to be led Silk;
The scale strip develops under x-ray bombardment.
In the preparation method that the present invention is provided, several scale strips are directly conveyed the length direction of core filaments along micro-wire It is welded in conveying core filaments and the mapping micro-wire of present invention offer is provided.
The scale strip develops under x-ray bombardment.The material of the scale strip is preferably platinum, platinum alloy, gold, nickel and closes Gold, titanium alloy or rustless steel.The width of the scale strip is preferably 0.2~1mm.The length of the scale strip is preferably defeated with described Send the girth of core filaments excircle equal.
The present invention is not particularly limited to the source of the micro-wire, commercially available.The micro-wire includes conveying core filaments. The micro-wire preferably also includes the conductive filament head being connected with conveying core filaments.The conductive filament head connection end decision design of the conveying core filaments Into the taper of Diameter Gradual Change, for improving the compliance of conductive filament head.It is described conveying core filaments material be preferably Nitinol and/or Rustless steel.The diameter of the conveying core filaments is preferably 0.20~1.0mm.The length of the conveying core filaments is preferably 130~ 300cm.The surface of the conveying core filaments is preferably coated with hydrophilic layer or hydrophobic layer.The material of the hydrophilic layer is preferably polyethylene Ketopyrrolidine, the material of the hydrophobic layer is preferably politef.The material of the conductive filament head be preferably platinum, platinum alloy, tungsten, Billon or rustless steel.The conductive filament head is preferably turned to by tinsel, helically spring-like.The diameter wiry is preferred For 0.05~0.25mm.External diameter of the conductive filament head of the helically spring-like along the section of its axis is preferably 0.20~1.0mm. The conductive filament head of the helically spring-like is preferably 5~100mm along the length of its axis
In the present invention, by the mode that some scale strips are welded on micro-wire conveying core filaments be preferably soldering or Laser welding.In brazing process, the temperature of the soldering is preferably 200~500 DEG C.In laser beam welding, the Laser Welding The electric current for connecing is preferably 50~140A, and the pulsewidth of the laser welding is preferably 3.0~10ms, and the frequency of the laser welding is excellent Elect 3~15Hz as.
The preparation method provided using the present invention can be obtained in conveying core filaments the micro-wire for being provided with scale strip, i.e. mapping Micro-wire.Mapping micro-wire can accurately measure the size at vascular lesion position, and such as aneurysm diameter, aneurysm neck breadth and blood vessel is narrow Narrow segment length etc., is particularly well-suited to the measurement of tortuous vascular lesion spot size.
For the sake of becoming apparent from, it is described in detail below by following examples.
Embodiment 1
Prepare mapping micro-wire
6~12 scale strips are welded in conveying core filaments along the length direction that micro-wire conveys core filaments, the welding of employing Mode is soldering, and brazing temperature is 200~500 DEG C.Mapping micro-wire shown in prepared Fig. 1.Fig. 1 is that the embodiment of the present invention is provided Mapping micro-wire structural representation, wherein 1 be conveying core filaments, 2 is several scale strips, and 3 is conductive filament head.
In the present embodiment, the material for conveying core filaments 1 is Nitinol, and a diameter of 0.2mm, length is 130cm, conveys core 1 surface-coated of silk has the polyvinylpyrrolidone hydrophilic layer that thickness is 0.006mm.Scale strip 2 is arranged in conveying core filaments 1, is carved The material of degree bar 2 is platinum, and width is 0.2mm, and length is 0.2 π mm, and the spacing of adjacent scale strip 2 is 0.5mm.Conductive filament head 3 with it is defeated The conductive filament head linkage section for sending core filaments 1 is connected, and the conductive filament head connection end is the taper of Diameter Gradual Change.Conductive filament head 3 is by a diameter of The platinum alloy silk of 0.05mm is rich to be made, helically spring-like, and external diameter of the helical spring along the section of its axis is 0.20mm, spiral Spring is 5mm along the length of its axis.
Embodiment 2
Prepare mapping micro-wire
6~12 scale strips are welded in conveying core filaments along the length direction that micro-wire conveys core filaments, the welding of employing Mode is laser welding, and the electric current of laser welding is 50~140A, and the pulsewidth of laser welding is 3.0~10ms, laser welding Frequency is 3~15Hz.Mapping micro-wire shown in prepared Fig. 1.Fig. 1 is that mapping micro-wire structure provided in an embodiment of the present invention is shown It is intended to, wherein 1 is conveying core filaments, 2 is several scale strips, and 3 is conductive filament head.
In the present embodiment, the material for conveying core filaments 1 is rustless steel, and a diameter of 1.0mm, length is 300cm, conveys core filaments 1 surface-coated has the politef hydrophobic layer that thickness is 0.025mm.Scale strip 2 is arranged in conveying core filaments 1, scale strip 2 Material is gold, and width is 1.0mm, and length is 1.0 π mm, and the spacing of adjacent scale strip 2 is 3mm.Conductive filament head 3 and conveying core filaments 1 Conductive filament head linkage section is connected, and the conductive filament head connection end is the taper of Diameter Gradual Change.Conductive filament head 3 is stainless by a diameter of 0.25mm's Steel wire is rich to be made, helically spring-like, and external diameter of the helical spring along the section of its axis is 1.0mm, and helical spring is along its axis Length be 100mm.
Embodiment 3
Prepare mapping micro-wire
6~12 scale strips are welded in conveying core filaments along the length direction that micro-wire conveys core filaments, the welding of employing Mode is soldering, and brazing temperature is 200~500 DEG C.Mapping micro-wire shown in prepared Fig. 1.Fig. 1 is that the embodiment of the present invention is provided Mapping micro-wire structural representation, wherein 1 be conveying core filaments, 2 is several scale strips, and 3 is conductive filament head.
In the present embodiment, the material for conveying core filaments 1 is Nitinol and rustless steel, a diameter of 0.6mm, and length is 200cm.Scale strip 2 is arranged in conveying core filaments 1, and the material of scale strip 2 is Nitinol, and width is 0.6mm, and length is 0.6 π Mm, the spacing of adjacent scale strip 2 is 1.5mm.Conductive filament head 3 is connected with the conductive filament head linkage section of conveying core filaments 1, and the conductive filament head connects Connect taper of the end for Diameter Gradual Change.Conductive filament head 3 is had mercy on by the tungsten filament of a diameter of 0.15mm and is made, helically spring-like, helical spring External diameter along the section of its axis is 0.6mm, and helical spring is 50mm along the length of its axis.
Embodiment 4
Measurement aneurysm
As shown in Fig. 2 Fig. 2 is mapping micro-wire provided in an embodiment of the present invention measures aneurysmal use schematic diagram, its In, 4 is aneurysm, and 5 is blood vessel, and 6 is mapping micro-wire.Mapping micro-wire 6 obtained in any embodiment of embodiment 1~3 is passed Target blood 5 is delivered to, micro-wire scale strip can pass through the width and scale of the high scale bar of micro-wire 6 under aneurysm neck, X-ray The distance measurement of bar goes out aneurysm diameter or aneurysm neck width.
Embodiment 5
Measurement angiostenosiss section
As shown in figure 3, Fig. 3 is the use schematic diagram that mapping micro-wire provided in an embodiment of the present invention measures blood vessel, wherein, 7 is angiostenosiss pathological changes, and 8 is blood vessel, and 9 is mapping micro-wire.By mapping micro-wire 9 obtained in any embodiment of embodiment 1~3 Be delivered to target blood 8, micro-wire scale strip across angiostenosiss section, can pass through under X-ray the high scale bar of micro-wire 9 width and The distance measurement of scale strip goes out blood vessel narrow section length.
The above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art For member, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications also should It is considered as protection scope of the present invention.

Claims (8)

1. a kind of preparation method of mapping micro-wire, comprises the following steps:
Several scale strips are welded in conveying core filaments along the length direction that micro-wire conveys core filaments, mapping micro-wire is obtained; The scale strip develops under x-ray bombardment;
The mode of welding is laser welding;The electric current of the laser welding is 50~140A, and the pulsewidth of the laser welding is 3.0 ~10ms, the frequency of the laser welding is 3~15Hz.
2. preparation method according to claim 1, it is characterised in that the material of the scale strip be platinum, platinum alloy, gold, Nickel alloy, titanium alloy or rustless steel.
3. preparation method according to claim 1, it is characterised in that the scale strip is along the cylindrical of the conveying core filaments The raised item that week is arranged.
4. preparation method according to claim 1, it is characterised in that the width of the scale strip is 0.2~1mm.
5. preparation method according to claim 1, it is characterised in that the spacing of the adjacent scale strip is 0.5~3mm.
6. preparation method according to claim 1, it is characterised in that the spacing of the adjacent scale strip is equal.
7. preparation method according to claim 1, it is characterised in that the micro-wire also includes conductive filament head, the seal wire Head is connected with the conveying core filaments.
8. preparation method according to claim 7, it is characterised in that the material of the conductive filament head be platinum, platinum alloy, tungsten, Billon or rustless steel.
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105288820A (en) * 2015-12-09 2016-02-03 仇汉诚 Medical facility and micro guide wire thereof
CN106264750B (en) * 2016-10-21 2023-11-14 复旦大学附属华山医院 Electrocoagulation hook measuring device and measuring method
CN114145733A (en) * 2020-09-07 2022-03-08 先健科技(深圳)有限公司 Measuring device, measuring system and measuring method

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CN201223393Y (en) * 2008-05-27 2009-04-22 黄优华 Balloon catheter for length measurement with graduate
CN204500704U (en) * 2015-03-12 2015-07-29 湖南埃普特医疗器械有限公司 A kind of mapping micro-wire

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WO2010150145A1 (en) * 2009-06-23 2010-12-29 Koninklijke Philips Electronics N.V. Device sizing support during interventions

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CN201076667Y (en) * 2007-09-14 2008-06-25 吴建华 J-shaped medical catheter kit
CN201223393Y (en) * 2008-05-27 2009-04-22 黄优华 Balloon catheter for length measurement with graduate
CN204500704U (en) * 2015-03-12 2015-07-29 湖南埃普特医疗器械有限公司 A kind of mapping micro-wire

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Effective date of registration: 20230118

Address after: 1049, Floor 1, Guoyuan Xili (shopping mall), Miyun Town, Miyun District, Beijing, 101500

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Address before: No. 009, Xiangxiang Avenue, Xiangxiang Economic Development Zone, Xiangtan City, Hunan Province 411400

Patentee before: APT MEDICAL Inc.