CN104605848A - Intracranial cortex electrode - Google Patents
Intracranial cortex electrode Download PDFInfo
- Publication number
- CN104605848A CN104605848A CN201410164133.2A CN201410164133A CN104605848A CN 104605848 A CN104605848 A CN 104605848A CN 201410164133 A CN201410164133 A CN 201410164133A CN 104605848 A CN104605848 A CN 104605848A
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- Prior art keywords
- electrode
- flexible substrates
- intracranial
- wire electrode
- intracranial skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/25—Bioelectric electrodes therefor
- A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
- A61B5/291—Bioelectric electrodes therefor specially adapted for particular uses for electroencephalography [EEG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
- A61B5/6868—Brain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0209—Special features of electrodes classified in A61B5/24, A61B5/25, A61B5/283, A61B5/291, A61B5/296, A61B5/053
Abstract
The invention discloses an intracranial cortex electrode. The intracranial cortex electrode is composed of an insulated flexible substrate, multiple electrode points embedded in the flexible substrate, electrode wires buried in the flexible substrate and electrode sleeves collecting the electrode wires. Due to a channel formed in the flexible substrate, obstructive tissue fluid between the electrode and brain tissue can be easily discharged, the fitness of the electrode on the brain tissue can be improved, and then monitoring quality can be guaranteed; besides, the intracranial deep electrode can enter the deep brain conveniently through the channel to detect brain electrical activity signals of deep brain tissue. Meanwhile, according to needs, a reinforcing net can be buried in the flexible substrate, and different electrode wire outlets can be formed in the flexible substrate.
Description
Technical field
The present invention relates to a kind of electrode for sensing, the biological electric wave of record intracranial, particularly a kind of intracranial skin electrode.
Background technology
The brain of the mankind is continuing to send faint bioelectrical signals, and these bioelectrical signals are called as brain wave, is that of cerebral activity situation intuitively embodies.By monitoring and studying these faint signals of telecommunication, we can understand physiological status real-time in brain.Brain diseases or cerebral tissue pathological changes can cause abnormal cerebral tissue electric discharge, this meeting of special epileptics causes the disease of the strong paradoxical discharge of brain, doctor can be helped to determine kind and the pathogenetic position of disease of disease by the monitor cerebral signal of telecommunication, for determining that therapeutic scheme provides valuable information.
People use the disc-shaped metal electric limit with wire to be attached on scalp the earliest, and EEG signals brain being diffused to this point of scalp is collected and carried out the research of brain wave figure after being passed to signal amplifying apparatus process, and this electrode is called scalp electrode.This monitoring method is simple to operation, patient is not born, but due to the stop of skull and scalp, very disperse and faint when eeg signal is passed to scalp, and usually with many interfering signals, be therefore difficult to accurately locate the position that in brain, this EEG signals sends.
There is the epidural electrode directly electrode electricity being placed in human brain exterior dura surface subsequently.This electrode is owing to directly contacting cerebral dura mater, and due to the interference without skull and scalp tissue, epidural electrode can detect brain electrical acti signal more accurately.But because cerebral dura mater still has interference for EEG signals, and the object of the monitor cerebral signal of telecommunication is the region in order to divide epileptogenic zone, so that subsequent procedures removal of lesions, epidural electrode cannot observe the situation of brain surface embedding Shi doctor, is also just difficult to divide focus brain surface accurately.
Up-to-date eeg monitoring technology is intracranial skin electrode, this electrode directly contacts Cerebral cortex surface, doctor can obtain the most direct EEG signals in brain top layer, the signal intensity that this place obtains is high, resolution is high, can obtain abundant data for doctor's examination by means such as high and low frequency filtering.This eeg monitoring method has become the goldstandard determining brain paradoxical discharge position in epileptics diagnosis, is widely used in the diagnosis of epileptics and neurosurgery.The matrix of intracranial skin electrode is transparent, clearly can observe the structure of brain surface, facilitate doctor to make Region dividing accurately when being embedded in brain surface, is also that excision focus provides direct image-guidance below.
Intracranial skin electrode is when covering cerebral tissue, and the tissue fluid existed due to cerebral tissue surface easily intercepts electrode and contacts with cerebral tissue, thus causes the weak or signal deletion of signal.Equally can because the tissue fluid at cerebral tissue secretory tissue liquid or other positions be infiltrated to cause the weak or disappearance of signal between electrode and cerebral tissue in the process of electrode monitoring.Simultaneously because brain surface is arc surface, the intracranial skin electrode of rectangular planes is due to the limitation of self softness and level of stretch, unavoidably in the situation that there will be some part not docile, cause electrode points and cerebral tissue surface contact unstable, affect EEG signals reception.Under some need long-term embedding situation, soft silica gel matrix because damaged by External Force Acting, may cause second operation imbedded electrode again.
Summary of the invention
In view of this, the invention provides a kind of intracranial skin electrode, the technical scheme adopted of its technical solution problem is as follows:
A kind of intracranial skin electrode, comprise the flexible substrates of insulation, the multiple electrode points be embedded in flexible substrates, be embedded in the wire electrode in flexible substrates and collect the electrode sleeve pipe of wire electrode, in addition, also comprise the passage in flexible substrates, described channel setting is in flexible substrates blank space.
Preferably, described wire electrode exit position is arranged on arbitrary place in flexible substrates one end or flexible substrates.
Preferably, reinforcing mat is inlaid with in described flexible substrates.
Preferably, described wire electrode is provided with wire electrode stopping means.
Preferably, the edge of described flexible substrates is provided with arc groove.
Preferably, the flexible base material of described insulation is selected from one or more in medical silica-gel, polyurethane, polypropylene, politef, polyethylene.
Preferably, described electrode points be mid portion projection circular piece, square plate, rectangular pieces, ellipse slice, triangular piece, one in ring segment; Described electrode points material is selected from one or more in medical stainless steel, platinumiridio, platinum, silver, gold, titanium, titanium alloy, Nitinol.
Preferably, described wire electrode material is selected from one or more in medical stainless steel, platinumiridio, nichrome, titanium, titanium alloy.
Preferably, described wire electrode Surface coating has insulant, and described insulant is selected from one or more in polyurethane, politef, Parylene, polrvinyl chloride.
Compared with prior art, the beneficial effect of intracranial skin electrode of the present invention is:
1. arrange passage in flexible substrates blank space, the shape of passage can need to be designed to rectangular, circular, square, rhombus etc. according to clinical.These passages contribute to discharging the tissue fluid intercepted between electrode and cerebral tissue, improve the sticking nature of electrode on cerebral tissue, and then ensure monitoring quality.
2. intracranial skin electrode only can gather the EEG signals of cortical surface in use, if desired detects the brain electrical acti signal of brain deep tissue simultaneously, then needs to insert Intracranical deep electrode.Because intracranial skin electrode is covered in cerebral tissue surface, what can stop Intracranical deep electrode inserts path, therefore offers passage at flexible substrates blank position, and Intracranical deep electrode can be facilitated to enter cerebral deep from passage.
3. in flexible base, embedding reinforcing mat can increase intensity and the service life of cortical electrode.
4. wire electrode is embedded among flexible substrates, after electrode somewhere is collected, extend to plug connector end from the conduit being connected to flexible substrates.The position of wire electrode outlet can be one end of flexible substrates, also can from somewhere flexible substrates.Different electrodes silk exit position can affect electrode in operative process and put.The skull needing first to open on skull certain area of inserting of intracranial skin electrode exposes brain, inserts electrode rear electrode sleeve pipe and passes skull opening connection external detection equipment.The position of wire electrode outlet and mode, limit the embedding method of electrode and position.Different wire electrode exit positions can meet the clinical demand of diversification.
5. the special arc groove that leaves of electrode rim, can improve the sticking nature of intracranial skin electrode arc-shaped brain surface, improves signal detection stability.
6. arrangement wire electrode at random can be gathered together by wire electrode stopping means, substrate reserves more blank position, makes the structure in electrode matrix more regular simultaneously, contribute to the lifting of its sticking nature.
Accompanying drawing explanation
In order to be illustrated more clearly in the embodiment of the present invention or technical scheme of the prior art, be briefly described to the accompanying drawing used required in embodiment or description of the prior art below, apparently, accompanying drawing in the following describes is only some embodiments of the present invention, for those of ordinary skill in the art, under the prerequisite not paying creative work, other accompanying drawing can also be obtained according to these accompanying drawings.
Fig. 1 is first embodiment mesocrany endodermis electrode structure schematic diagram provided by the invention;
Fig. 2 is second embodiment mesocrany endodermis electrode structure schematic diagram provided by the invention;
Fig. 3 is the 3rd embodiment mesocrany endodermis electrode structure schematic diagram provided by the invention;
Fig. 4 is the 4th embodiment mesocrany endodermis electrode structure schematic diagram provided by the invention;
Fig. 5 is the 5th embodiment mesocrany endodermis electrode structure schematic diagram provided by the invention.
Detailed description of the invention
Below in conjunction with the accompanying drawing in the embodiment of the present invention, be clearly and completely described the technical scheme in the embodiment of the present invention, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
Embodiment 1
As shown in Figure 1, a kind of intracranial skin electrode of the present invention, is made up of the flexible substrates 1 insulated, the multiple electrode points 2 be embedded in flexible substrates, the electrode sleeve pipe 4 that is embedded in the wire electrode 3 in flexible substrates and collects wire electrode.
In embodiment 1 as shown in the figure, further aspect of the present invention is: flexible substrates 1 blank space offers passage 5.These passages not only contribute to discharging the tissue fluid intercepted between electrode and cerebral tissue, improve the sticking nature of electrode on cerebral tissue, and then ensure monitoring quality; And, when needing to insert Intracranical deep electrode and detecting the brain electrical acti signal of brain deep tissue further, facilitate Intracranical deep electrode to enter cerebral deep from passage.
In the present invention, the flexible base material of described insulation is selected from medical silica-gel; The length of described flexible substrates is 40mm, and width is 40m; Described electrode points is the circular piece of mid portion projection, and bossing diameter is 2.5mm; The arrangement mode of described electrode points is 4 × 8, and electrode points spacing is 10mm; Described electrode points material is selected from medical stainless steel; Described wire electrode material is selected from medical stainless steel, and diameter is 0.07mm; The surface coated insulant of described wire electrode is polyurethane; The length of described electrode sleeve pipe is 300mm.
Embodiment 2
As shown in Figure 2, a kind of intracranial skin electrode of the present invention, is made up of the flexible substrates 1 insulated, the multiple electrode points 2 be embedded in flexible substrates, the electrode sleeve pipe 4 that is embedded in the wire electrode 3 in flexible substrates and collects wire electrode.
In embodiment 2 as shown in the figure, further aspect of the present invention is: flexible substrates 1 blank space offers passage 5.These passages not only contribute to discharging the tissue fluid intercepted between electrode and cerebral tissue, improve the sticking nature of electrode on cerebral tissue, and then ensure monitoring quality; And, when needing to insert Intracranical deep electrode and detecting the brain electrical acti signal of brain deep tissue further, facilitate Intracranical deep electrode to enter cerebral deep from passage.In addition, the edge of flexible substrates 1 is provided with arc groove 6, can improve the sticking nature of intracranial skin electrode arc-shaped brain surface, improves signal detection stability.
In the present invention, the flexible base material of described insulation is selected from polyurethane; The length of described flexible substrates is 80mm, and width is 40m; Described electrode points is the circular piece of mid portion projection, and bossing diameter is 2.5mm; The arrangement mode of described electrode points is 4 × 8, and electrode points spacing is 10mm; Described electrode points material is selected from platinumiridio; Described wire electrode material is selected from platinumiridio, and diameter is 0.07mm; The surface coated insulant of described wire electrode is politef; The length of described electrode sleeve pipe is 500mm.
Embodiment 3
As shown in Figure 3, a kind of intracranial skin electrode of the present invention, is made up of the flexible substrates 1 insulated, the multiple electrode points 2 be embedded in flexible substrates, the electrode sleeve pipe 4 that is embedded in the wire electrode 3 in flexible substrates and collects wire electrode.
In embodiment 3 as shown in the figure, further aspect of the present invention is: flexible substrates 1 blank space offers passage 5.These passages not only contribute to discharging the tissue fluid intercepted between electrode and cerebral tissue, improve the sticking nature of electrode on cerebral tissue, and then ensure monitoring quality; And, when needing to insert Intracranical deep electrode and detecting the brain electrical acti signal of brain deep tissue further, facilitate Intracranical deep electrode to enter cerebral deep from passage.In addition, the edge of flexible substrates 1 is provided with arc groove 6, can improve the sticking nature of intracranial skin electrode arc-shaped brain surface, improves signal detection stability.In addition, in flexible substrates 1, be provided with wire electrode stopping means 8, can wire electrode be strapped in together, make its regular array in flexible substrate, contribute to the lifting of sticking nature.
In the present invention, the flexible base material of described insulation is selected from polypropylene; The length of described flexible substrates is 80mm, and width is 40m; Described electrode points is the ellipse slice of mid portion projection, and bossing diameter is 2.5mm; The arrangement mode of described electrode points is 4 × 8, and electrode points spacing is 10mm; Described electrode points material is selected from platinum; Described wire electrode material is selected from platinumiridio, and diameter is 0.05mm; The surface coated insulant of described wire electrode is Parylene; The length of described electrode sleeve pipe is 300mm.
Embodiment 4
As shown in Figure 4, a kind of intracranial skin electrode of the present invention, is made up of the flexible substrates 1 insulated, the multiple electrode points 2 be embedded in flexible substrates, the electrode sleeve pipe 4 that is embedded in the wire electrode 3 in flexible substrates and collects wire electrode.
In embodiment 4 as shown in the figure, further aspect of the present invention is: flexible substrates 1 blank space offers passage 5.These passages not only contribute to discharging the tissue fluid intercepted between electrode and cerebral tissue, improve the sticking nature of electrode on cerebral tissue, and then ensure monitoring quality; And, when needing to insert Intracranical deep electrode and detecting the brain electrical acti signal of brain deep tissue further, facilitate Intracranical deep electrode to enter cerebral deep from passage.In addition, the edge of flexible substrates 1 is provided with arc groove 6, can improve the sticking nature of intracranial skin electrode arc-shaped brain surface, improves signal detection stability.In addition, wire electrode exit position 7 arranges on a flexible substrate, can meet the clinical demand of diversification.
In the present invention, the flexible base material of described insulation is selected from politef; The length of described flexible substrates is 80mm, and width is 40m; Described electrode points be mid portion projection circular piece, bossing diameter is 2.5mm; The arrangement mode of described electrode points is 4 × 8, and electrode points spacing is 10mm; Described electrode points material is selected from titanium; Described wire electrode material is selected from titanium alloy, and diameter is 0.07mm; The surface coated insulant of described wire electrode is polrvinyl chloride; The length of described electrode sleeve pipe is 400mm.
Embodiment 5
As shown in Figure 5, a kind of intracranial skin electrode of the present invention, is made up of the flexible substrates 1 insulated, the multiple electrode points 2 be embedded in flexible substrates, the electrode sleeve pipe 4 that is embedded in the wire electrode 3 in flexible substrates and collects wire electrode.
In embodiment 5 as shown in the figure, further aspect of the present invention is: flexible substrates 1 blank space offers passage 5.These passages not only contribute to discharging the tissue fluid intercepted between electrode and cerebral tissue, improve the sticking nature of electrode on cerebral tissue, and then ensure monitoring quality; And, when needing to insert Intracranical deep electrode and detecting the brain electrical acti signal of brain deep tissue further, facilitate Intracranical deep electrode to enter cerebral deep from passage.In addition, in flexible substrates 1, be provided with reinforcing mat 9, intensity and the service life of cortical electrode can be increased.
In the present invention, the flexible base material of described insulation is selected from polyethylene; The length of described flexible substrates is 40mm, and width is 40m; Described electrode points be mid portion projection circular piece, bossing diameter is 2.5mm; The arrangement mode of described electrode points is 4 × 4, and electrode points spacing is 10mm; Described electrode points material is selected from titanium; Described wire electrode material is selected from titanium alloy, and diameter is 0.05mm; The surface coated insulant of described wire electrode is polrvinyl chloride; The length of described electrode sleeve pipe is 350mm.
Embodiment 6-18
To the above-mentioned explanation of the disclosed embodiments, professional and technical personnel in the field are realized or uses the present invention.To be apparent for those skilled in the art to the multiple amendment of these embodiments, General Principle as defined herein can without departing from the spirit or scope of the present invention, realize in other embodiments.Therefore, the present invention can not be restricted to these embodiments shown in this article, but will meet the widest scope consistent with principle disclosed herein and features of novelty.
Claims (9)
1. an intracranial skin electrode, comprise the flexible substrates of insulation, the multiple electrode points be embedded in flexible substrates, be embedded in the wire electrode in flexible substrates and collect the electrode sleeve pipe of wire electrode, it is characterized in that, also comprise the passage in flexible substrates, described channel setting is in flexible substrates blank space.
2. intracranial skin electrode according to claim 1, is characterized in that, described wire electrode exit position is arranged on arbitrary place in flexible substrates one end or flexible substrates.
3. the intracranial skin electrode according to any one of claim 1 claim, is characterized in that, is inlaid with reinforcing mat in described flexible substrates.
4. the intracranial skin electrode according to any one of claims 1 to 3 claim, is characterized in that, described wire electrode is provided with wire electrode stopping means.
5. the intracranial skin electrode according to any one of Claims 1 to 4 claim, is characterized in that, the edge of described flexible substrates is provided with arc groove.
6. intracranial skin electrode according to claim 1, is characterized in that, the flexible base material of described insulation is selected from one or more in medical silica-gel, polyurethane, polypropylene, politef, polyethylene.
7. intracranial skin electrode according to claim 1, is characterized in that, described electrode points be mid portion projection circular piece, square plate, rectangular pieces, ellipse slice, triangular piece, one in ring segment; Described electrode points material is selected from one or more in medical stainless steel, platinumiridio, platinum, silver, gold, titanium, titanium alloy, Nitinol.
8. intracranial skin electrode according to claim 1, is characterized in that, described wire electrode material is selected from one or more in medical stainless steel, platinumiridio, nichrome, titanium, titanium alloy.
9. intracranial skin electrode according to claim 1, is characterized in that, described wire electrode Surface coating has insulant, and described insulant is selected from one or more in polyurethane, politef, Parylene, polrvinyl chloride.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410164133.2A CN104605848A (en) | 2014-04-23 | 2014-04-23 | Intracranial cortex electrode |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410164133.2A CN104605848A (en) | 2014-04-23 | 2014-04-23 | Intracranial cortex electrode |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105380623A (en) * | 2015-12-11 | 2016-03-09 | 吉林大学 | Device used for detecting cerebral blood flow and electroencephalogram under epileptics state |
| CN106388817A (en) * | 2016-12-01 | 2017-02-15 | 科斗（苏州）脑机科技有限公司 | Novel air pressure type microwire electrode |
| CN106420046A (en) * | 2016-09-30 | 2017-02-22 | 北京迈迪顶峰医疗科技有限公司 | Integral electrode |
| CN109645991A (en) * | 2019-01-02 | 2019-04-19 | 华南理工大学 | It is a kind of intelligence encephalic cortical electrode and its precise acquisition cortex brain electricity method |
| CN113049150A (en) * | 2021-02-02 | 2021-06-29 | 诺瑞(深圳)新技术有限公司 | Flexible pressure sensor, preparation method thereof, robot skin and wearable equipment |
| CN113057639A (en) * | 2021-03-17 | 2021-07-02 | 清华大学 | Flexible brain electrode and preparation method thereof |
| CN113349783A (en) * | 2021-06-08 | 2021-09-07 | 深圳市神经科学研究院 | Intracranial electrode plate |
| CN115381458A (en) * | 2022-08-31 | 2022-11-25 | 上海脑虎科技有限公司 | Brain electrode device, preparation method thereof, electrode device and electronic equipment |
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