CN104146698A - Device for detecting blood volume and tissue metabolism abnormalities - Google Patents
Device for detecting blood volume and tissue metabolism abnormalities Download PDFInfo
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- CN104146698A CN104146698A CN201410408807.9A CN201410408807A CN104146698A CN 104146698 A CN104146698 A CN 104146698A CN 201410408807 A CN201410408807 A CN 201410408807A CN 104146698 A CN104146698 A CN 104146698A
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Abstract
Provided is a device for detecting a blood volume and tissue metabolism abnormalities. A light emitting diode array is composed of a plurality of light emitting points, and each light emitting point is composed of at least one light emitting diode. The input end of the light emitting diode array is connected to the output end of a light emitting diode array driving circuit through a first multiplexer. The address input end of the first multiplexer is connected to a control unit, and the light emitting points in the light emitting diode array are selected through control of the control unit. The input end of the light emitting diode array driving circuit is connected to the control unit, and preset power is output according to the control of the control unit. A light-sensitive detector array is composed of a plurality of light-sensitive detectors. The output end of the light-sensitive detector array is connected to the input end of an analog signal processing unit through a second multiplexer. The address input end of the second multiplexer is connected to the control unit. The output end of the analog signal processing unit is connected to the input end of an analog-digital conversion unit, and the output end of the analog-digital conversion unit is connected to the control unit.
Description
Technical field
The present invention relates to a kind of medicinal detection device, relate in particular to a kind of for detection of the abnormal device of blood flow volume and tissue metabolism.
Background technology
In prior art, the histiocytic detection of pathological changes is had to a variety of methods.Taking breast carcinoma as example, comprise mammary X-ray photography (breast molybdenum target photograph), color ultrasound, also can carry out if desired mammary gland magnetic resonance inspection (MRI).But these technology are all could use after lesion tissue occurring, are unfavorable for early prevention and the discovery of disease.
Summary of the invention
For this reason, the present invention is intended to propose a kind of for detection of the abnormal device of blood flow volume and tissue metabolism, and it can detect the Developmental and Metabolic Disorder of blood flow volume and tissue.
In order to reach above-mentioned purpose, the present invention proposes a kind of for detection of the abnormal device of blood flow volume and tissue metabolism, and it comprises light emitting diode matrix, light-sensitive detector array, the first MUX, the second MUX, light emitting diode matrix drive circuit, analogy signal processing unit, AD conversion unit, control unit; Light emitting diode matrix is made up of multiple luminous points, and each luminous point is made up of at least one light emitting diode, for launching the light that enters tissue; The input of light emitting diode matrix is connected to the outfan of light emitting diode matrix drive circuit by the first MUX; The address input end of the first MUX is connected to control unit, selects the luminous point in light emitting diode matrix by the control of control unit; The input of light emitting diode matrix drive circuit is connected to control unit, exports predetermined power according to the control of control unit; Light-sensitive detector array is made up of multiple light-sensitive detectors, for receiving the light reflecting from tissue; The outfan of light-sensitive detector array is connected to the input of analogy signal processing unit by the second MUX; The address input end of the second MUX is connected to control unit, selects the light-sensitive detector in photosensitive detector array by the control of control unit; The outfan of analogy signal processing unit is connected to the input of AD conversion unit, and the outfan of AD conversion unit is connected to control unit.
Preferably, light emitting diode matrix and light-sensitive detector arranged in arrays are on same body.
Preferably, described body is flexible.
Preferably, each luminous point of described light emitting diode matrix by multiple light-sensitive detectors of described light-sensitive detector array around.
Preferably, the drive current of described light emitting diode matrix drive circuit output is variable.
Preferably, described each luminous point is made up of the light emitting diode of two docking, the optical band difference that described two light emitting diodes send.
Of the present inventionly pass through tissue for detection of the abnormal device of blood flow volume and tissue metabolism by photon, determine situation and position that tissue metabolism is abnormal, diseases prevention is in possible trouble.
Brief description of the drawings
Fig. 1 is the theory diagram for detection of the abnormal device of blood flow volume and tissue metabolism of the present invention;
Fig. 2 is the schematic diagram of the body for detection of the abnormal device of blood flow volume and tissue metabolism of the present invention;
State diagram schematic diagram when Fig. 3 is a luminous point job in body;
Fig. 4 detects the work schematic diagram while organizing with of the present invention for detection of the abnormal device of blood flow volume and tissue metabolism;
Fig. 5 is the banana effect schematic diagram that photon is propagated in tissue.
Detailed description of the invention
Below, be elaborated for detection of the abnormal device of blood flow volume and tissue metabolism to of the present invention by reference to the accompanying drawings.
The present invention mainly utilizes photon banana effect in tissue to detect the metabolism situation of tissue, as shown in Figure 5.
Be the abnormal device of detection blood flow volume of the present invention and tissue metabolism as Figure 1-3, it mainly comprises light emitting diode matrix 20, light-sensitive detector array 30, the first MUX 22,23, the second MUX 33,34, light emitting diode matrix drive circuit 21, analogy signal processing unit 31, AD conversion unit 32, control unit 10; Light emitting diode matrix 20 is made up of multiple luminous points, and each luminous point is made up of at least one light emitting diode, for launching the light that enters tissue; The input of light emitting diode matrix 20 is connected to the outfan of light emitting diode matrix drive circuit 21 by the first MUX 22,23; The address input end of the first MUX 22,23 is connected to control unit 10, selects the luminous point in light emitting diode matrix 20 by the control of control unit 10; The input of light emitting diode matrix drive circuit 21 is connected to control unit 10, exports predetermined power according to the control of control unit 10; Light-sensitive detector array 30 is made up of multiple light-sensitive detectors, for receiving the light reflecting from tissue; The outfan of light-sensitive detector array 30 is connected to the input of analogy signal processing unit 31 by the second MUX 33,34; The address input end of the second MUX 33,34 is connected to control unit 10, selects the light-sensitive detector in photosensitive detector array 30 by the control of control unit 10; The outfan of analogy signal processing unit 31 is connected to the input of AD conversion unit 32, and the outfan of AD conversion unit 32 is connected to control unit 10.Here, analogy signal processing unit 31 completes filtering and signal amplification.Analogue signal is converted to digital signal by AD conversion unit 32, realized by A/D circuit.
Light emitting diode matrix 20 is arranged on same body 50 with light-sensitive detector array 30, and preferably, body 50 is made for flexible material, fits to facilitate with the skin surface of human body.As shown in Figure 2,3, the luminous point 25 of light emitting diode matrix 20 is arranged crosswise with the light-sensitive detector 35 of light-sensitive detector array 30, makes each luminous point 25 around around being provided with multiple light-sensitive detectors 35.
Each luminous point can comprise a light emitting diode, can be also two or more light emitting diodes.Be preferably two light emitting diodes.In the time being two light emitting diodes, the wave band difference of these two light emitting diodes, is preferably 640nm and 940nm, and type of attachment is head and the tail docking, and two light emitting diodes send the light of different-waveband, to carry out the detection of tissue oxygenation.In the time carrying out blood flow volume measurement, only need a kind of light of wave band.
When work, controller 10 is lighted the luminous point in Light-Emitting Diode array 20 successively, controls corresponding light-sensitive detector in light-sensitive detector array 30 simultaneously and receives light, and here, light-sensitive detector can be light sensitive diode.By calculating volumetric blood and/or blood oxygen from surveying the photometry obtaining, judge the tissue that whether has Developmental and Metabolic Disorder in this corresponding region.By the common factor of different corresponding regions, determine the position of Developmental and Metabolic Disorder tissue.Because photon propagation path in the tissue of high scattering becomes banana-shaped, the effective depth that photon can be surveyed and light source become certain relation to the distance of photoelectric detector, in the time will detecting compared with the blood flow volume of deep tissues and/or blood oxygen saturation, need to select light source right to the larger luminous and reception of photoelectric detector distance, now need to increase light source drive current.Otherwise the luminous and reception that chosen distance is less is right, reduces light source drive current simultaneously.
As shown in Figure 4, control unit is lighted luminous point 25 successively, 26, 27, respectively by light-sensitive detector 35, 36 receive, the photon of process histiocyte 60 is by light-sensitive detector 35, after 36, it be can calculate and blood flow volume and/or blood oxygen calculated, whether the metabolism that judges itself and peripheral cell with this is variant, the tachytrophism such as whether and have the probability of canceration, by calculate luminous point 26 to the path of light-sensitive detector 36 and luminous point 25 to the path of light-sensitive detector 35, can further obtain their cross point, thereby obtain the position of Developmental and Metabolic Disorder cell 60.
Owing to can determine the position of Developmental and Metabolic Disorder cell by the present invention; can accomplish to eliminate extremely with regard to finding and taking appropriate measures in time before pathological changes; especially aspect Breast Cancer Prevention; before cell carcinogenesis, just can determine that cellular metabolism is abnormal; for example metabolism is very active, prevents early and nurses one's health.
Claims (6)
1. for detection of the abnormal device of blood flow volume and tissue metabolism, it comprises light emitting diode matrix, light-sensitive detector array, the first MUX, the second MUX, light emitting diode matrix drive circuit, analogy signal processing unit, AD conversion unit, control unit;
Light emitting diode matrix is made up of multiple luminous points, and each luminous point is made up of at least one light emitting diode, for launching the light that enters tissue; The input of light emitting diode matrix is connected to the outfan of light emitting diode matrix drive circuit by the first MUX; The address input end of the first MUX is connected to control unit, selects the luminous point in light emitting diode matrix by the control of control unit; The input of light emitting diode matrix drive circuit is connected to control unit, exports predetermined power according to the control of control unit;
Light-sensitive detector array is made up of multiple light-sensitive detectors, for receiving the light reflecting from tissue; The outfan of light-sensitive detector array is connected to the input of analogy signal processing unit by the second MUX; The address input end of the second MUX is connected to control unit, selects the light-sensitive detector in photosensitive detector array by the control of control unit; The outfan of analogy signal processing unit is connected to the input of AD conversion unit, and the outfan of AD conversion unit is connected to control unit.
2. as claimed in claim 1 for detection of the abnormal device of blood flow volume and tissue metabolism, it is characterized in that: light emitting diode matrix and light-sensitive detector arranged in arrays are on same body.
3. as claimed in claim 2 for detection of the abnormal device of blood flow volume and tissue metabolism, it is characterized in that: described body is flexible.
4. as claimed in claim 1 for detection of the abnormal device of blood flow volume and tissue metabolism, it is characterized in that: each luminous point of described light emitting diode matrix by multiple light-sensitive detectors of described light-sensitive detector array around.
5. as claimed in claim 1 for detection of the abnormal device of blood flow volume and tissue metabolism, it is characterized in that: the drive current of described light emitting diode matrix drive circuit output is variable.
6. as claimed in claim 1 for detection of the abnormal device of blood flow volume and tissue metabolism, it is characterized in that: described each luminous point is made up of the light emitting diode of two docking the optical band difference that described two light emitting diodes send.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410408807.9A CN104146698B (en) | 2014-08-19 | 2014-08-19 | For detecting the device of blood flow volume and tissue metabolism's exception |
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| CN201410408807.9A CN104146698B (en) | 2014-08-19 | 2014-08-19 | For detecting the device of blood flow volume and tissue metabolism's exception |
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| CN104146698A true CN104146698A (en) | 2014-11-19 |
| CN104146698B CN104146698B (en) | 2016-03-09 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106725323A (en) * | 2016-12-22 | 2017-05-31 | 中国科学院苏州生物医学工程技术研究所 | Wearable biological signal collecting device |
| CN107550498A (en) * | 2016-06-30 | 2018-01-09 | 北京超思电子技术有限责任公司 | A kind of blood oxygen measuring device and its measuring method |
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| WO1994016613A1 (en) * | 1993-01-25 | 1994-08-04 | Synectics Medical Ab | Ambulatory recording of the presence and activity of substances in gastro-intestinal compartments |
| US5560372A (en) * | 1994-02-02 | 1996-10-01 | Cory; Philip C. | Non-invasive, peripheral nerve mapping device and method of use |
| CN1924556A (en) * | 2005-08-29 | 2007-03-07 | 深圳雷杜生命科学股份有限公司 | Optical path system for clinical test analyzer |
| CN103622703A (en) * | 2013-12-05 | 2014-03-12 | 深圳市奥博莱特科技有限公司 | Human tissue blood oxygen saturation degree absolute amount detection device and method |
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2014
- 2014-08-19 CN CN201410408807.9A patent/CN104146698B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994016613A1 (en) * | 1993-01-25 | 1994-08-04 | Synectics Medical Ab | Ambulatory recording of the presence and activity of substances in gastro-intestinal compartments |
| US5560372A (en) * | 1994-02-02 | 1996-10-01 | Cory; Philip C. | Non-invasive, peripheral nerve mapping device and method of use |
| CN1924556A (en) * | 2005-08-29 | 2007-03-07 | 深圳雷杜生命科学股份有限公司 | Optical path system for clinical test analyzer |
| CN103622703A (en) * | 2013-12-05 | 2014-03-12 | 深圳市奥博莱特科技有限公司 | Human tissue blood oxygen saturation degree absolute amount detection device and method |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107550498A (en) * | 2016-06-30 | 2018-01-09 | 北京超思电子技术有限责任公司 | A kind of blood oxygen measuring device and its measuring method |
| CN107550498B (en) * | 2016-06-30 | 2024-02-09 | 北京超思电子技术有限责任公司 | Blood oxygen measuring device and measuring method thereof |
| CN106725323A (en) * | 2016-12-22 | 2017-05-31 | 中国科学院苏州生物医学工程技术研究所 | Wearable biological signal collecting device |
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| CN104146698B (en) | 2016-03-09 |
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Effective date of registration: 20200601 Address after: 100853 Fuxing Road, Beijing, Haidian District, No. 28 Patentee after: Shi-Ming Yang Address before: 100853 room 3, building 1, building 25, Taiping Road, No. 503, Beijing, Haidian District Patentee before: Wang Weidong |
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