CN104027867A - Portable intelligent dual-function diabetes treatment pump - Google Patents

Portable intelligent dual-function diabetes treatment pump Download PDF

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Publication number
CN104027867A
CN104027867A CN201410267094.9A CN201410267094A CN104027867A CN 104027867 A CN104027867 A CN 104027867A CN 201410267094 A CN201410267094 A CN 201410267094A CN 104027867 A CN104027867 A CN 104027867A
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blood glucose
portable intelligent
insulin
blood
merit
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CN201410267094.9A
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杨力
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Individual
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Abstract

The invention relates to a diabetes treatment pump and discloses a portable intelligent dual-function diabetes treatment pump comprising an indicator light, a housing, buttons, a power switch, a buzzer, an LED screen, an insulin liquor tube, a glucagon liquor tube, an insulin liquor infusion tube, an infusion needle, a glucagon liquor infusion tube, a blood glucose detection sensor, a blood glucose detection sampling needle, a blood glucose data transmission line, a main board, a power supply, and a driver. The portable intelligent dual-function diabetes treatment pump has the advantages that the process that the pancreas controls the blood glucose can be simulated; insulin or glucagon is injected in real time by detecting the glucose in real time and analyzing and calculating through an injection control model, the glucose level is kept in the certain safety range, closed-loop control of insulin or glucagon injection is achieved, and high glucose level or low glucose level is prevented; data is output by external communication equipment in real time and serves a reference for doctors to diagnose the illness; the portable intelligent dual-function diabetes treatment pump is small in size and convenient to carry; life quality of diabetics can be improved greatly and safely; the demands of diabetics for health and treatment are truly met; medication safety is ensured; the portable intelligent dual-function diabetes treatment pump has promising popularization and application prospect.

Description

The two merit treating diabetes pumps of portable intelligent
Technical field
The present invention relates to a kind of diabetes mellitus therapeutic device, particularly relate to the two merit treating diabetes pumps of a kind of portable intelligent.
Background technology
The insulin physiology value of human intervention diabetics is the Main Means for the treatment of at present diabetes and other insulin deficit disease.Mainly contain at present medicine irritation autocrine and the direct large class of supplementation with insulin two, wherein directly supplementary form has injection and oral (not yet sizing) two kinds.Existing insulin pump can give automatically in predetermined time the insulin of pre-determined amount, and it has realized automatically supplementing of insulin, substantially can meet Treatment need idealized, stable diabetes mellitus patient.But, because the blood glucose value of human body is a kind of various factors, dynamic, random changing value of being subject to, and current all kinds of insulin pumps all cannot to blood sugar for human body numerical value automatically implement monitoring in real time and for human body requirements dynamically to amount, and have the excessive hypoglycemic problem causing of injection of insulin, so cannot accomplish the real health that meets patient, treatment needs.
Insulin and glicentin are respectively two kinds of materials that are used for controlling blood glucose of pancreas secretion, insulin is used for blood sugar lowering, glicentin is used for glycemic, the main cause of diabetes is afunction of pancreas, and current all kinds of insulin pumps are all just confined to the use of insulin, replacing there is very large defect aspect pancreatic functions.
Summary of the invention
(1) technical problem that will solve
The technical problem to be solved in the present invention is Real-Time Monitoring blood glucose numerical value, according to this numerical value, carry out in real time the injection of insulin or glicentin, guarantee that blood glucose value is in certain scope always, realize the closed loop control of insulin or glicentin injection, prevent that blood glucose situation higher or on the low side from occurring, and real time output data is carried out reference for the diagnosis state of an illness.
(2) technical scheme
In order to solve the problems of the technologies described above, the invention provides the two merit treating diabetes pumps of a kind of portable intelligent, it comprises: display lamp, shell, button, on and off switch, buzzer, LED display, insulin drug liquid tube, glicentin drug liquid tube, insulin tube for transfusion, infusion syringe needle, glicentin tube for transfusion, blood-sugar detection sensor, blood sugar test sampling syringe needle, blood glucose level data transmission line, mainboard, power supply, driver.
(3) beneficial effect
The two merit treating diabetes pumps of portable intelligent that technique scheme provides, can simulate pancreas and control the process of blood glucose, by the real-time detection to blood glucose, by analysis, complete the real-time injection of insulin or glicentin, guarantee that blood glucose value is in certain safety range always, realize the closed loop control of insulin or glicentin injection, prevent that blood glucose situation higher or on the low side from occurring, and for the diagnosis state of an illness, carry out reference by external communications equipment real time output data, volume is little, be easy to carry, can obviously improve patient's quality of life, the real health that meets patient, treatment needs, guarantee drug safety, possesses popularizing application prospect widely.
Accompanying drawing explanation
Fig. 1 is the panel construction schematic diagram of the two merit treating diabetes pumps of portable intelligent of the embodiment of the present invention;
Fig. 2 is the two merit treating diabetes pump structure schematic diagrams of the portable intelligent of the embodiment of the present invention;
Fig. 3 is that the infusion of the two merit treating diabetes pumps of portable intelligent of the embodiment of the present invention is controlled illustraton of model.
Wherein, 1: display lamp; 2: shell; 3: button; 4: on and off switch; 5: buzzer; 6:LED display screen; 7: insulin drug liquid tube; 8: glicentin drug liquid tube; 9: insulin tube for transfusion; 10: infusion syringe needle; 11: glicentin tube for transfusion; 12: blood-sugar detection sensor; 13: blood sugar test sampling syringe needle; 14: blood glucose level data transmission line; 15: mainboard; 16: power supply; 17: driver.
The specific embodiment
Below in conjunction with drawings and Examples, the specific embodiment of the present invention is described in further detail.Following examples are used for illustrating the present invention, but are not used for limiting the scope of the invention.
Fig. 1 shows the panel construction schematic diagram of the two merit treating diabetes pumps of the present embodiment portable intelligent, shown in Fig. 1, display lamp 1 and buzzer 5 are for warning, when the situations such as abnormal (too high or too low) appears in blood glucose value, electric weight is not enough, medicinal liquid surplus is too low occur, display lamp 1 flicker, buzzer 5 sends caution sound.Shell 2 adopts ABS material.Button 3 is for checking blood glucose level data and injectable drug situation in the past, blood glucose show value being calibrated, regulated the brightness of LED display 6 etc.When calibration blood glucose show value, can puncture finger tip and measure current blood glucose value, with the comparison of blood glucose show value, when having error, can use button to be calibrated to actual value.LED display 6 can show the situations such as the medicinal liquid type of current blood glucose value, current use and dosage, dump energy.
Fig. 2 shows the two merit treating diabetes pump structure schematic diagrams of the present embodiment portable intelligent, shown in Fig. 2, insulin drug liquid tube 7 is used for storing insulin medicinal liquid, glicentin drug liquid tube 8 is used for storing glicentin medicinal liquid, because insulin in reality is higher than glicentin frequency of utilization, so the Capacity Ratio glicentin drug liquid tube 8 of insulin drug liquid tube 7 is larger.In insulin drug liquid tube 7 and glicentin drug liquid tube 8, be provided with liquid level sensor, when medicinal liquid surplus is very few, can send warning by display lamp 1 and buzzer 5.In order to prevent coiling, together with insulin tube for transfusion 9 is adjacent with glicentin tube for transfusion 11, one end is connected on insulin drug liquid tube 7 and glicentin drug liquid tube 8, and the other end is connected on infusion syringe needle 10 jointly.For fear of the bidirectional-reflux of insulin and glicentin, need to guarantee that the hydraulic pressure of two medicinal liquids is identical during this period, so larger than glicentin tube for transfusion 11 of the diameter of insulin tube for transfusion 9.Blood sugar test sampling syringe needle 13 can carry out real-time sampling to blood, via blood-sugar detection sensor 12, measures blood glucose value, blood glucose level data can be transferred to and on mainboard 15, be carried out the work such as subsequent analysis by blood glucose level data transmission line 14.For fear of the infusion of medicinal liquid, affect the precision of blood sugar test, infusion syringe needle 10 samples with blood sugar test the different parts that syringe needle 13 thrusts respectively human body, and distance should be more than or equal to 250mm, should be arranged on the position of difficult drop-off.Driver 17 consists of motor, 1~2 decelerator etc., for promoting the medicinal liquid of insulin drug liquid tube 7 or glicentin drug liquid tube 8, thereby completes the infusion of corresponding medicinal liquid, and infusion precision can reach 0.1Ge unit, total amount error < 5%.Mainboard 15 can be analyzed, calculate the blood glucose level data transmitting from blood glucose level data transmission line 14, according to different results, send the different signals of telecommunication to driver 17, make it carry out the infusion of medicinal liquid, and the information such as the kind of real-time blood glucose value, infusion medicinal liquid and consumption are presented on LED display 6, when blood glucose is higher or on the low side, send signal display lamp 1 and buzzer 5 are given the alarm.Storage chip and Bluetooth chip are housed on mainboard 15, storage of history data P can be got off, and by bluetooth, these historical datas are sent in mobile phone automatically, by free netses such as Fetion, micro-letters, send in the terminal of hospital or section office again, set up medical archive, doctor's medical advice also can feed back at any time.When having serious problems, send at once information, when there is no serious problems, periodically send information, for example once a day.Power supply 16 can adopt aneroid battery or lithium battery.
Fig. 3 shows the infusion of the two merit treating diabetes pumps of the present embodiment portable intelligent and controls illustraton of model, shown in Fig. 3, and abscissa express time, vertical coordinate represents user blood glucose value.Slope of a curve represents the rate of change of user blood glucose, and user's blood glucose amount is directly proportional to the insulin level in user's body.Concrete coefficient, because everyone difference of individuality is different, need to be demarcated.The infusion of the two merit treating diabetes pumps of portable intelligent is controlled model, and the logical relation of infusion is to adopt different priority levels, that is: artificial priority → 5.8 standard controlled stage.According to people's normal physiological demand, keep blood sugar for human body content within standard error scope.According to medical experiment, suppose that normal person's blood sugar content is on an empty stomach 5.8, the range of error that human body allows is ± 0.2.In the time of outside blood sugar for human body content is allowing domain of walker, report to the police and infusion of insulin or glicentin.If t constantly, A on the actual measurement blood glucose curve that blood-sugar detection sensor 12 obtains 0the blood sugar monitoring value of point is 5.8, when arriving t ain the time of constantly, the actual measurement blood glucose value that A is ordered is V a, slope of a curve is k: V a=k (t a-t 0)+5.8, change of blood sugar value △ V=V a-5.8=k (t a-t 0).Because the characteristic of human body is different, the pass of amount of insulin secretion and blood sugar content is a specific curves, that is: Q=cV, and wherein c is constant, the infusion amount △ Q=c △ V of insulin.So, △ Q=ck (t a-y 0).In the time of in △ V is allowing domain of walker, do not report to the police, belong to normal allowed band; When △ V reaches the upper limit or lower the prescribing a time limit that allows domain of walker, report to the police, but driver 17 does not start; When △ V surpass to allow the upper of domain of walker, report to the police in limited time, and according to the blood glucose value variable quantity detecting to the corresponding insulin of infusion in user's body; When △ V is lower than allowing the lower of domain of walker to report to the police in limited time, and according to the blood glucose value variable quantity detecting to the corresponding glicentin of infusion in user's body.
Use the workflow of the two merit treating diabetes pumps of the present embodiment portable intelligent to be described below: with it the pump housing is fixed on, as belt or pocket, infusion syringe needle 10 and blood sugar test sampling syringe needle 13 are thrust respectively to the different parts of human body, distance should be at least 250mm, should be arranged on the position of difficult drop-off.Turn on the power switch 4, the two merit treating diabetes pumps of portable intelligent are started working, by blood sugar test, sample the real-time blood sampling of syringe needle 13, by blood-sugar detection sensor 12, detect current blood glucose value, and be transferred in mainboard 15 by blood glucose level data transmission line 14, by infusion, controlling model analyzes blood glucose level data, when blood glucose value is higher or on the low side, send the signal of telecommunication and make display lamp 1 flicker, buzzer 5 sends caution sound, make driver 17 according to practical situation, inject insulin or the glicentin of amount of calculation, medicinal liquid arrives infusion syringe needle 10 by insulin tube for transfusion 9 or glicentin tube for transfusion 11, thereby injection human body, reach the effect of stabilizing blood sugar.Mainboard 15 is presented at the information such as the kind of real-time blood glucose value, infusion medicinal liquid and consumption on LED display 6, and regularly sends historical data to hospital terminal by bluetooth, sets up medical archive.
As can be seen from the above embodiments, the present invention can simulate the process that pancreas is controlled blood glucose, by the real-time detection to blood glucose, by analysis, complete the real-time injection of insulin or glicentin, guarantee that blood glucose value is in certain safety range always, realize the closed loop control of insulin or glicentin injection, prevent that blood glucose situation higher or on the low side from occurring, and for the diagnosis state of an illness, carry out reference by external communications equipment real time output data, volume is little, be easy to carry, can obviously improve patient's quality of life, the real health that meets patient, treatment needs, guarantee drug safety, possesses popularizing application prospect widely.
The above is only the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, do not departing under the prerequisite of the technology of the present invention principle; can also make some improvement and replacement, these improvement and replacement also should be considered as protection scope of the present invention.

Claims (9)

1. the two merit treating diabetes pumps of portable intelligent, is characterized in that, comprising: display lamp, shell, button, on and off switch, buzzer, LED display, insulin drug liquid tube, glicentin drug liquid tube, insulin tube for transfusion, infusion syringe needle, glicentin tube for transfusion, blood-sugar detection sensor, blood sugar test sampling syringe needle, blood glucose level data transmission line, mainboard, power supply, driver.
2. two merit treating diabetes pumps of portable intelligent as claimed in claim 1, it is characterized in that, in described insulin drug liquid tube, store insulin, blood sugar lowering when higher for blood glucose, in described glicentin drug liquid tube, store glicentin, glycemic for blood glucose when on the low side, reaches the object of stabilizing blood sugar by two-way function.
3. two merit treating diabetes pumps of portable intelligent as claimed in claim 1, it is characterized in that, described mainboard can be controlled model by infusion blood glucose level data is carried out to real-time analysis calculating, and by controlling insulin or the glicentin of described driver infusion respective numbers, blood glucose numerical control, in safety range, is reached to the object of closed loop control blood glucose.
4. the two merit treating diabetes pumps of portable intelligent as claimed in claim 3, is characterized in that, described infusion is controlled model and can be analyzed real-time blood glucose level data, contrasts with normal value, determines type and the consumption of infusion medicine.
5. the two merit treating diabetes pumps of portable intelligent as claimed in claim 1, is characterized in that, described blood sugar test sampling syringe needle and described infusion syringe needle thrust respectively the diverse location of body surface, and distance should be more than or equal to 250mm.
6. two merit treating diabetes pumps of portable intelligent as claimed in claim 1, it is characterized in that, after described blood sugar test sampling syringe needle samples blood, by described blood-sugar detection sensor, detect current blood glucose value, by described blood glucose level data transmission line, in described mainboard, carry out the work such as subsequent analysis.
7. two merit treating diabetes pumps of portable intelligent as claimed in claim 1, it is characterized in that, storage chip and Bluetooth chip are housed on described mainboard, storage of history data P can be got off, and by bluetooth, these historical datas are sent in mobile phone automatically, by free netses such as Fetion, micro-letters, send in the terminal of hospital or section office, set up medical archive, doctor's medical advice also can feed back at any time.
8. two merit treating diabetes pumps of portable intelligent as claimed in claim 1, it is characterized in that, described display lamp and buzzer are used for warning, when the situations such as abnormal (too high or too low) appears in blood glucose value, electric weight is not enough, medicinal liquid surplus is too low occur, described display lamp flicker, described buzzer sends caution sound.
9. two merit treating diabetes pumps of portable intelligent as claimed in claim 1, it is characterized in that, described button for checking blood glucose level data and injectable drug situation in the past, blood glucose show value is calibrated, is regulated the brightness of described LED display etc., described LED display can show the situations such as the medicinal liquid type of current blood glucose value, current use and dosage, dump energy.
CN201410267094.9A 2014-06-13 2014-06-13 Portable intelligent dual-function diabetes treatment pump Pending CN104027867A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108904927A (en) * 2018-08-28 2018-11-30 珠海市富立信医疗设备应用技术开发有限公司 A kind of intelligent injection system and method
CN110914913A (en) * 2017-08-09 2020-03-24 欧姆龙健康医疗事业株式会社 Data processing device, data processing method, and data processing program
CN110960758A (en) * 2019-12-10 2020-04-07 南通大学 Full-function insulin syringe
CN113663160A (en) * 2021-07-27 2021-11-19 武汉联影智融医疗科技有限公司 Injection device and medical instrument
WO2023071012A1 (en) * 2021-10-25 2023-05-04 Medtrum Technologies Inc. Fully closed-loop artificial pancreas drug infusion control system

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CN102836481A (en) * 2012-09-29 2012-12-26 哈尔滨工业大学 Novel insulin pump
CN102946923A (en) * 2010-06-22 2013-02-27 美敦力迷你迈德公司 Method and/or system for closed-loop control of glucose to a treatment range
US20140163517A1 (en) * 2012-12-07 2014-06-12 Animas Corporation Method and system for tuning a closed-loop controller for an artificial pancreas

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WO2004009161A1 (en) * 2002-07-24 2004-01-29 Medtronic Minimed, Inc. A physiological monitoring device for controlling a medication infusion device
US20120191063A1 (en) * 2004-02-26 2012-07-26 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
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Publication number Priority date Publication date Assignee Title
CN110914913A (en) * 2017-08-09 2020-03-24 欧姆龙健康医疗事业株式会社 Data processing device, data processing method, and data processing program
CN108904927A (en) * 2018-08-28 2018-11-30 珠海市富立信医疗设备应用技术开发有限公司 A kind of intelligent injection system and method
CN110960758A (en) * 2019-12-10 2020-04-07 南通大学 Full-function insulin syringe
CN110960758B (en) * 2019-12-10 2022-03-25 南通大学 Full-function insulin syringe
CN113663160A (en) * 2021-07-27 2021-11-19 武汉联影智融医疗科技有限公司 Injection device and medical instrument
CN113663160B (en) * 2021-07-27 2024-01-23 武汉联影智融医疗科技有限公司 Insulin glucagon injection device and medical instrument
WO2023071012A1 (en) * 2021-10-25 2023-05-04 Medtrum Technologies Inc. Fully closed-loop artificial pancreas drug infusion control system

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