CN104023783B - Medical guide wire - Google Patents

Medical guide wire Download PDF

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Publication number
CN104023783B
CN104023783B CN201380004444.6A CN201380004444A CN104023783B CN 104023783 B CN104023783 B CN 104023783B CN 201380004444 A CN201380004444 A CN 201380004444A CN 104023783 B CN104023783 B CN 104023783B
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China
Prior art keywords
resin
helical spring
heart yearn
winder
sparse
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CN201380004444.6A
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CN104023783A (en
Inventor
奥村亮一
河崎浩范
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Japan Lifeline Co Ltd
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Japan Lifeline Co Ltd
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Publication of CN104023783A publication Critical patent/CN104023783A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09Guide wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09Guide wires
    • A61M2025/09058Basic structures of guide wires
    • A61M2025/09083Basic structures of guide wires having a coil around a core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09Guide wires
    • A61M2025/09166Guide wires having radio-opaque features

Abstract

The invention provides medical guide wire, have: heart yearn (10), it has amphi position side minor diameter part (11) and peri position side large-diameter portion (14), and helical spring (20), it is installed on the periphery of amphi position side minor diameter part (11), it is that the sparse winder of rear end side (22) of 1.8 ~ 2.5 times of coil wire diameter is formed that the front that helical spring (20) is 1.0 ~ 1.8 times of coil wire diameter by coil pitch is closely wound portion (21) and coil pitch, resin (40) is filled with in the inside of the sparse winder of rear end side (22), and be formed in its periphery by the resin bed of this resin formation (40A), stackedly on the surface of resin bed (40A) be formed with hydrophilic resin cover layer (50), the periphery that front is closely wound portion (21) is not covered by resin, but expose the constituent material of helical spring (20).According to this wire, have good lubricity in distal end section, the property inserted is good, and endovascular information can be grasped as resistance (change) fully in hands side, and can reliably advance towards object position.

Description

Medical guide wire
Technical field
The present invention relates to the helical spring medical guide wire on the periphery with the amphi position side minor diameter part being installed on heart yearn.
Background technology
For the wire for being guided towards endoceliac assigned positions such as blood vessels by the medical apparatus such as conduit (catheter), require the pliability of distal end section, flexibility.
Therefore, known following such wire, it makes the external diameter of the distal end section of heart yearn less than the external diameter of peri position end, and in the periphery of the distal end section (amphi position side minor diameter part) of heart yearn, helical spring is installed, thus attempt improves the pliability (referenced patent document 1) of distal end section.
In addition, introduce to have and be filled with resin in the helical spring inside of the distal end section being installed on heart yearn, and be formed in helical spring periphery by the resin bed of above-mentioned resin formation, the stacked wire (referenced patent document 2) being formed with hydrophilic resin lipid layer on the surface of this resin bed.By forming hydrophilic resin lipid layer in helical spring periphery, lubricity can be given to the distal end section of wire, thus the insertion of wire can be improved.
Patent documentation 1: Japanese Unexamined Patent Publication 2003-299739 publication
Patent documentation 2: Japanese Unexamined Patent Publication 2010-214054 publication
For the endovascular information (such as, the situation of the diseased region such as narrow, occlusive part) being inserted with wire, operator is by feeling that by feel the resistance (change) of the vascular site that the distal end section of wire contacts is grasped.
But, as the wire described in above-mentioned patent documentation 2, for cover in helical spring periphery be formed with hydrophilic resin lipid layer wire for, almost experience less than resistance as described above (change), therefore make the grasp of information become difficult.
In addition, though such wire obtains good lubricity, its distal end section of another side becomes easy slip, is therefore difficult to wire to advance towards object position.
And, owing to almost experiencing less than resistance (change), so that the front end load of more than desirable value must be applied, thus there is worry blood vessel being caused to damage.
On the other hand, such as, when to microchannel (microchannel) interpolation admittance line in CTO pathological changes, being undertaken the fore-end bending of wire to formalize by operator (is shaped: operation shaping).
But, as the wire described in above-mentioned patent documentation 2, for be filled with the wire of resin in helical spring inside for, be difficult to form operation due to the resin of filling at fore-end.
Summary of the invention
The present invention produces based on above situation.
The object of the present invention is to provide a kind of medical guide wire, it has good lubricity in distal end section, the insertion of wire is good, and endovascular information can being grasped as resistance (change) fully in hands side, and the medical guide wire that can reliably advance towards object position.
Other objects of the present invention are to provide a kind of medical guide wire that more easily can form operation.
(1) medical guide wire of the present invention has: heart yearn, and it has amphi position side minor diameter part and the external diameter peri position side large-diameter portion larger than above-mentioned amphi position side minor diameter part; And
Helical spring, it is axially installed on the periphery of the amphi position side minor diameter part of above-mentioned heart yearn, and is at least fixed on above-mentioned heart yearn in leading section and rearward end,
The feature of above-mentioned medical guide wire is,
It is that the sparse winder of rear end side of 1.8 ~ 2.5 times of coil wire diameter is formed that the front that above-mentioned helical spring is 1.0 ~ 1.8 times of coil wire diameter by coil pitch is closely wound portion and coil pitch,
Be filled with resin in the inside of the sparse winder of above-mentioned rear end side, and be formed by the resin bed of above-mentioned resin formation in the periphery of the sparse winder of above-mentioned rear end side, stackedly on the surface of above-mentioned resin bed be formed with hydrophilic resin cover layer,
The periphery that above-mentioned front is closely wound portion is not covered by resin, but exposes above-mentioned helical spring constituent material.
According to the medical guide wire of such structure, the periphery that front is closely wound portion is not covered by resin, but expose helical spring constituent material, thus the endovascular information being inserted with wire can be grasped (information transitivity is superior) as resistance (change) fully in hands side.
In addition, due to the information of the vascular site that the front portion of being closely wound contacts can be grasped fully, and the front portion of being closely wound is difficult to slide, so medical guide wire of the present invention reliably can be advanced (set direction of wire is superior) towards endovascular object position.
In addition, by being filled with resin in the inside of the sparse winder of rear end side, heart yearn can be made integrated with helical spring (the sparse winder of rear end side), thus moment of torsion transitivity, the operability (moment of torsion transitivity is superior) of wire can be improved.
In addition, owing to being formed with resin bed in the periphery of the sparse winder of rear end side, stackedly on the surface of this resin bed be formed with hydrophilic resin cover layer, so have hydrophilic resin cover layer via the resin bed by the resin formation identical with the inside being filled in the sparse winder of rear end side at the periphery stratification of the sparse winder of rear end side, therefore hydrophilic resin cover layer can reliably be fixed, and stably can manifest the preferred lubricity (hydrophilic resin cover layer is superior relative to the close property of the periphery of the sparse winder of rear end side) of hydrophilic resin.
(2) in medical guide wire of the present invention, the inside being preferably closely wound portion in above-mentioned front is not filled with resin.
According to such structure, can guarantee that front is closely wound pliability, the flexibility in portion fully, in helical spring (front is closely wound portion), easily can form operation.
(3) in medical guide wire of the present invention, the external diameter (D of the peri position side large-diameter portion of preferred above-mentioned heart yearn 1) and above-mentioned helical spring coil outer diameter (D 2) below 0.012 inch,
Above-mentioned helical spring length (L 2) be 51 ~ 800mm,
Above-mentioned front is closely wound the length (L in portion 21) be 1 ~ 50mm,
Length (the L of the sparse winder of above-mentioned rear end side 22) be 50 ~ 750mm.
(4) in medical guide wire of the present invention, preferably include above-mentioned helical spring front and be closely wound portion and the sparse winder of rear end side at interior pars intermedia, be fixed on above-mentioned heart yearn by solder.
(5) in the medical guide wire of above-mentioned (4), preferred above-mentioned helical spring leading section and pars intermedia, by being fixed on above-mentioned heart yearn containing gold brazing filler metal.
(6) in medical guide wire of the present invention, preferred above-mentioned heart yearn is made up of rustless steel.
According to medical guide wire of the present invention, in distal end section, there is good lubricity, and the property inserted is good, and endovascular information can be grasped in hands side fully as resistance (change), and reliably can advance towards object position.
In addition, by being filled with resin in the inside of the sparse winder of rear end side, make moment of torsion transitivity superior.
In addition, according to the medical guide wire of the present invention possessing the front not being filled with resin in inside and be closely wound portion, more easily operation can be formed.
Accompanying drawing explanation
Fig. 1 is by the side view of a part of cutting of an embodiment of expression wire of the present invention.
Fig. 2 is by the side view (figure for being described size) of a part of cutting of an embodiment of expression wire of the present invention.
Detailed description of the invention
Wire 1 shown in Fig. 1 and Fig. 2 is a kind of medical guide wire, and it has: heart yearn 10, and it has amphi position side minor diameter part 11 and the external diameter peri position side large-diameter portion 14 larger than amphi position side minor diameter part 11, and helical spring 20, it is axially installed on the periphery of the amphi position side minor diameter part 11 of heart yearn 10, and in leading section, pars intermedia and rearward end are fixed on heart yearn 10, helical spring 20 is that the front of 1.0 ~ 1.8 times of coil wire diameter is closely wound portion 21 by coil pitch, form with the sparse winder 22 of rear end side that coil pitch is 1.8 ~ 2.5 times of coil wire diameter, cured resin 40 is filled with in the inside of the sparse winder 22 of rear end side, and be formed with in the periphery of the sparse winder 22 of rear end side the resin bed 40A formed by this cured resin, stackedly on the surface of resin bed 40A be formed with hydrophilic resin cover layer 50, on the other hand, the periphery that front is closely wound portion 21 is not covered by resin, but expose the constituent material of helical spring 20, and the inside being closely wound portion 21 in front is not also by resin filling.
The wire 1 of present embodiment has heart yearn 10 and helical spring 20.Heart yearn 10 has and has carried out the amphi position side minor diameter part 11 of taper processing, tapered portion 13 that proximally direction is expanding and peri position side large-diameter portion 14 in the mode that proximally direction is expanding.
Amphi position side minor diameter part 11, tapered portion 13 and peri position side large-diameter portion 14 are made up of same wire rod (such as, pole parts) one.
The cross section of tapered portion 13 and peri position side large-diameter portion 14 is circular.
The cross section of the peri position side of amphi position side minor diameter part 11 is circular, but wire rod compression also can be become tabular by the amphi position side of amphi position side minor diameter part 11, and the cross section in this situation becomes substantially rectangular.
Material as heart yearn 10 is not particularly limited, though can list the metals such as rustless steel (such as SUS316, SUS304), gold, platinum, aluminum, tungsten, tantalum or these alloy, in the present embodiment, is made up of rustless steel.
In addition, hydrophobicity resin layer (omitting diagram) is formed with at the outer peripheral face of heart yearn 10.
Be as medical and resin that is that use as the resin forming hydrophobicity resin layer, the whole medical resin with hydrophobicity can be used, as preferred resin, can the fluororesin such as PTFE be listed.
Total length (the L of the wire 1 shown in Fig. 2 1) be such as 1500 ~ 3000mm, if illustrate a preferred example, be then 1780mm.
In addition, the external diameter (D of peri position side large-diameter portion 14 1) usually at 0.012 inch (0.305mm) below, preferably at 0.010 inch (0.254mm) below, be more preferably 0.006 ~ 0.010 inch, if illustrate a preferred example, be then 0.010 inch.
External diameter (the D of peri position side large-diameter portion 14 1) below 0.012 inch, therefore, it is possible to contribute to the miniaturization of the medical apparatus such as the conduit jointly used with wire of the present invention, and then can Wicresoft be contributed to.
As the maximum outside diameter of amphi position side minor diameter part 11, as long as less than the internal diameter of helical spring 20, be not particularly limited, but be formed as the external diameter (D of peri position side large-diameter portion 14 1) about 1/5 ~ 3/5.
Form the helical spring 20 of the wire 1 of present embodiment, be axially installed on the periphery of the amphi position side minor diameter part 11 of heart yearn 10.
Helical spring 20 is formed by a wire rod, and the front being 1.0 ~ 1.8 times of coil wire diameter by coil pitch is closely wound portion 21 and coil pitch is that the sparse winder 22 of rear end side of 1.8 ~ 2.5 times of coil wire diameter is formed, be closely wound portion 21 by front and front end described later point forms X-ray not penetrating region.
The coil pitch that front is closely wound portion 21 is 1.0 ~ 1.8 times of coil wire diameter, if illustrate a preferred example, is then 1.0 times.
The coil pitch of the sparse winder 22 of rear end side is 1.8 ~ 2.5 times of coil wire diameter, if illustrate a preferred example, is then 2.0 times.
Like this, by making coil pitch change in front and rear end side, portion 21 can be closely wound in front and manifest good radiography (visuality).
When the whole region of helical spring 20 is formed as same pitch, due to X-ray, penetrating region is not elongated, causes visual reduction.
Coil outer diameter (the D of helical spring 20 2) usually at 0.012 inch (0.305mm) below, preferably at 0.010 inch (0.254mm) below, be more preferably 0.006 ~ 0.010 inch, if illustrate a preferred example, be then 0.010 inch.
External diameter (the D of the peri position side large-diameter portion 14 of heart yearn 10 1) below 0.012 inch, and the coil outer diameter (D of helical spring 20 2) also below 0.012 inch, the operability (such as, the lubricity of microchannel) when therefore entering to microchannel is superior.
Though the external diameter forming the wire rod of helical spring 20 is not particularly limited, being preferably 30 ~ 90 μm, if illustrate a preferred example, is then 60 μm.
As the material of helical spring 20, the material (X-ray is penetrating material not) that platinum, White gold alloy (such as Pt/W=92/8), gold, gold-copper alloy, tungsten, tantalum etc. are good to the radiography of X-ray can be listed.
For the wire 1 of present embodiment, the leading section of helical spring 20, rearward end and pars intermedia (front is closely wound the boundary member of portion 21 and the sparse winder 22 of rear end side) utilize solder 31,32,33 respectively and are fixed on the periphery of the amphi position side minor diameter part 11 of heart yearn 10.
As shown in Figure 1, heart yearn 10 is fixed on by solder 31 in the leading section of helical spring 20.That is, solder 31 soaks into the inside in helical spring 20, and this solder 31 contacts with the periphery of heart yearn 10 (amphi position side minor diameter part 11), thus heart yearn 10 is fixed in the leading section of helical spring 20.
In addition, in the leading section of helical spring 20, form roughly hemispheric front end point by the solder 31 do not soaked in the inside of helical spring 20.Thus, in the leading section of wire, form the hard straight part in the front end that is made up of solder 31 (become by the solder 31 because soaking in coil inside cannot the hard straight part that forms of the fore-end of helical spring 20 of free bend and the front end point that formed by this solder 31).
In addition, the front comprising helical spring 20 is closely wound portion 21 and the pars intermedia of the borderline region of the sparse winder 22 of rear end side, is fixed on heart yearn 10 by solder 32.That is, solder 32 soaks into the inside in helical spring 20, and this solder 32 contacts with the periphery of heart yearn 10 (amphi position side minor diameter part 11), thus the pars intermedia of helical spring 20 is fixed on heart yearn 10.
And the rearward end of helical spring 20 is fixed on heart yearn 10 by solder 33.That is, solder 33 soaks into the inside in helical spring 20, and this solder 33 contacts with the periphery of heart yearn 10 (amphi position side minor diameter part 11), thus the rearward end of helical spring 20 is fixed on heart yearn 10.
As the solder 31,32 for the leading section of helical spring 20 and pars intermedia being individually fixed in heart yearn 10, preferably use containing gold brazing filler metal.
By using containing gold brazing filler metal as solder 31,32, helical spring 20 enough high relative to the constant intensity of heart yearn 10 (higher than the fracture strength of the amphi position side minor diameter part 11 of heart yearn 10) can be made, even if apply tensile force to the heart yearn 10 under the state inserting helical spring 20, heart yearn 10 also can not be pulled out.Herein, " containing gold brazing filler metal " comprises Au solder alloy and the Au solders such as Au-Sn brazing filler metal, Au-Ge brazing filler metal, Au-Si brazing filler metal, Au-In brazing filler metal, Au-Sb brazing filler metal.
On the other hand, as the solder 33 for the rearward end of helical spring 20 being fixed on heart yearn 10, the silver-colored brazing filler metals such as Ag-Sn system can be illustrated.
As shown in Figure 1, in the wire 1 of present embodiment, cured resin 40 is filled with in the inside of the sparse winder 22 of the rear end side of helical spring 20, and be formed with the resin bed 40A (covering the layer of the cured resin of coil wire rod) formed by this cured resin 40 in the periphery of the sparse winder 22 of rear end side, be formed with hydrophilic resin cover layer 50 the surface of this resin bed 40A is stacked.
Cured resin 40 is filled with in the inside of the sparse winder 22 of the rear end side of helical spring 20, thus make heart yearn 10 integrated with helical spring 20, the moment of torsion transitivity of wire is significantly improved, the rotation torque that the peri position side large-diameter portion 14 from heart yearn 10 transmits reliably is passed to the amphi position end of the helical spring 20 integrated with amphi position side minor diameter part 11.
In addition, resin bed 40A is formed in the periphery of the sparse winder 22 of the rear end side of helical spring 20, stackedly on the surface of this resin bed 40A be formed with hydrophilic resin cover layer 50 (being formed with hydrophilic resin cover layer 50 via resin bed 40A in the periphery of the sparse winder 22 of rear end side), therefore hydrophilic resin cover layer 50 is firmly fixed at helical spring 20, thereby, it is possible to stably show the suitable lubricity of hydrophilic resin.
Herein, form the cured resin 40 of resin bed 40A as the inside being filled in the sparse winder 22 of rear end side, preferably relative to both helical spring 20 and hydrophilic resin, all there is good fusible cured resin, specifically, can exemplify: the solidfied material etc. of the light-cured resins such as polyurethane acrylate resin, polyurethane resin, silicone resin, epoxy resin, acrylic resin, nylon resin or heat-curing resin.
As the thickness of the resin bed 40A of the periphery of the sparse winder 22 of covering rear end side, such as, be 1 ~ 100 μm, be preferably 3 ~ 10 μm.
As the stacked hydrophilic resin being formed at the hydrophilic resin cover layer 50 on the surface of resin bed 40A of formation, the known hydrophilic polymer of the hydrophilic process for medical instruments can be used.Specifically can exemplify: the polysaccharides such as Polyethylene Glycol, polyethylene glycol oxide, polyhydric alcohol, polyacrylamide, polyvinyl pyrrolidone, polyvinyl alcohol, polyethers, polyurethane, polycarboxylic acids and these derivant, cellulose, protein, hyaluronic acid.In addition, these hydrophilic polymeies also can have structure of building bridge.
As the thickness of hydrophilic resin lipid layer 50, such as, be 1 ~ 30 μm, be preferably 3 ~ 19 μm.
As the filling of cured resin 40 and the formation method of resin bed 40A, and the stratification method of hydrophilic resin 50 is not particularly limited, such as can enumerate following method: sparse for the rear end side of the helical spring 20 being installed on heart yearn 10 winder 22 be impregnated in curable resin, thus fill curable resin in the inside of the sparse winder 22 of rear end side, form resin bed on the surface of the sparse winder 22 of rear end side simultaneously, by its heat cure or photocuring are become cured resin 40 (resin bed 40A), then, utilize suitable method, at the surface-coated hydrophilic resin of resin bed 40A.
At this, when front being closely wound portion 21 and jointly impregnated in curable resin with the sparse winder 22 of rear end side, preferably the periphery that front is closely wound portion 21 is hidden etc., prevent curable resin to be closely wound the inside in portion 21 towards front and periphery flows into and attachment.
As shown in Figure 1, in the wire 1 of present embodiment, the periphery that the front of helical spring 20 is closely wound portion 21 is not covered by resin, but exposes the constituent material (X-ray is the metal such as penetrating material not) of helical spring 20.
Thereby, it is possible to the endovascular information (such as, the situation of the diseased region such as narrow, occlusive part) being inserted with the wire 1 of present embodiment is grasped in hands side fully as resistance (change).
In addition, the information that front is closely wound the vascular site that portion 21 contacts can be grasped fully, and be not closely wound portion 21 by the front that hydrophilic resin covers not easily to slide, therefore, it is possible to reliably the wire 1 of present embodiment is advanced towards endovascular object position.
In addition, in the wire 1 of present embodiment, the inside being closely wound portion 21 in front is not filled with resin.Thereby, it is possible to guarantee that front is closely wound pliability, the flexibility in portion 21 fully, thus easily can be closely wound portion 21 in front and form operation.
In addition, even if the inside being closely wound portion 21 in front is not filled with resin, also can by filling the moment of torsion transitivity that cured resin 40 guarantees wire 1 fully in the inside of the sparse winder 22 of rear end side.
Length (the L of the helical spring 20 shown in Fig. 2 2) be preferably 51 ~ 800mm, more preferably 85 ~ 310mm, if illustrate a preferred example, be then 115mm.
Front is closely wound the length (L in portion 21 21) be preferably 1 ~ 50mm, more preferably 20 ~ 40mm, if illustrate a preferred example, be then 30mm.
Length (the L of the sparse winder 22 of rear end side 22) be preferably 50 ~ 750mm, more preferably 65 ~ 270mm, if illustrate a preferred example, be then 85mm.
Length (the L in portion 21 is closely wound in the front of non-covering resin 21) too small when, cannot grasp the endovascular information being inserted with wire fully, in addition, the distal end section of wire becomes easy slip, thus is difficult to such wire to advance towards object position.
On the other hand, the length (L in portion 21 is closely wound in front 21) excessive when, the lubricity of the distal end section of wire is not enough, so that is such as difficult to make wire by narrow positions etc., thus damages the insertion of wire.
In addition, at the length (L of the sparse winder 22 of rear end side 22) too small when, the lubricity of the distal end section of wire is not enough and damage the insertion of wire.In addition, the moment of torsion transitivity of wire is sometimes damaged.
On the other hand, at the length (L because of the sparse winder 22 of rear end side 22) excessive and cause front to be closely wound the length (L in portion 21 21) relatively too small when, the endovascular information being inserted with wire cannot be grasped fully, in addition, be difficult to wire to advance towards object position.
Length (the L of the roughly hemispheric front end point formed by solder 31 3) be such as 0.1 ~ 5.0mm, if illustrate a preferred example, be then 0.3mm.
As described above, wire 1 according to the present embodiment, in the distal end section being provided with helical spring 20 (the sparse winder of rear end side 22), there is good lubricity, and it is good towards endovascular insertion, and the periphery that front is closely wound portion 21 is not covered by resin, but expose the constituent material (metal) of helical spring 20, thus endovascular information can be grasped as resistance (change) fully in hands side, and can reliably advance towards object position.
In addition, owing to being filled with cured resin 40, so moment of torsion transitivity is superior in the inside of the sparse winder 22 of rear end side.
In addition, because the inside being closely wound portion 21 in front is not filled with resin, therefore, it is possible to easily form operation.
Description of reference numerals
10... heart yearn; 11... amphi position side minor diameter part; 13... tapered portion; 14... peri position side large-diameter portion; 20... helical spring; 21... front is closely wound portion; 22... the sparse winder of rear end side; 31... solder; 32... solder; 33... solder; 40... cured resin; 40A... resin bed; 50... hydrophilic resin lipid layer.

Claims (6)

1. a medical guide wire,
Have:
Heart yearn, it has amphi position side minor diameter part and the external diameter peri position side large-diameter portion larger than described amphi position side minor diameter part; And
Helical spring, it is axially installed on the periphery of the amphi position side minor diameter part of described heart yearn, and is at least fixed on described heart yearn in leading section and rearward end,
The feature of described medical guide wire is,
It is that the sparse winder of rear end side of 1.8 ~ 2.5 times of coil wire diameter is formed that the front that described helical spring is 1.0 ~ 1.8 times of coil wire diameter by coil pitch is closely wound portion and coil pitch,
The inside of the sparse winder in side is filled with resin in the rear, and the periphery of the sparse winder in side is formed by the resin bed of described resin formation in the rear, stackedly on the surface of described resin bed is formed with hydrophilic resin cover layer,
The periphery that described front is closely wound portion is not covered by resin, but exposes described helical spring constituent material.
2. medical guide wire according to claim 1, is characterized in that,
The inside being closely wound portion in described front is not filled with resin.
3. medical guide wire according to claim 1 and 2, is characterized in that,
The outer diameter D of the peri position side large-diameter portion of described heart yearn 1and described helical spring coil outer diameter D 2below 0.012 inch,
Described helical spring length L 2be 51 ~ 800mm,
Described front is closely wound the length L in portion 21be 1 ~ 50mm,
The length L of the sparse winder of described rear end side 22be 50 ~ 750mm.
4. medical guide wire according to claim 1 and 2, is characterized in that,
Comprise the pars intermedia that described helical spring front is closely wound portion and the sparse winder of rear end side, be fixed on described heart yearn by solder.
5. medical guide wire according to claim 4, is characterized in that,
Described helical spring leading section and pars intermedia, by being fixed on described heart yearn containing gold brazing filler metal.
6. medical guide wire according to claim 1 and 2, is characterized in that,
Described heart yearn is made up of rustless steel.
CN201380004444.6A 2012-03-29 2013-02-08 Medical guide wire Active CN104023783B (en)

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JP2012-077045 2012-03-29
JP2012077045A JP5404840B2 (en) 2012-03-29 2012-03-29 Medical guidewire
PCT/JP2013/053077 WO2013145893A1 (en) 2012-03-29 2013-02-08 Medical guide wire

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CN104023783A CN104023783A (en) 2014-09-03
CN104023783B true CN104023783B (en) 2016-01-20

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HK (1) HK1200746A1 (en)
TW (1) TWI517869B (en)
WO (1) WO2013145893A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11173284B2 (en) * 2015-11-17 2021-11-16 Gunze Limited Medical guide wire
DE102016009871A1 (en) * 2016-08-12 2018-02-15 Häberle Laser- und Feinwerktechnik GmbH & Co. KG Guidewire for use in tubular medical probes, in particular for nutritional therapy
EP3508246B1 (en) * 2016-09-05 2021-08-11 Asahi Intecc Co., Ltd. Guide wire
JP6724251B2 (en) * 2017-06-29 2020-07-15 朝日インテック株式会社 Guide wire for plasma
EP3747498A4 (en) * 2018-02-01 2021-10-13 Asahi Intecc Co., Ltd. Guide wire
KR20230144761A (en) 2022-04-08 2023-10-17 성원메디칼 주식회사 Medical Micro Guide Wire

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5409470A (en) * 1993-05-07 1995-04-25 C. R. Bard, Inc. Dilatation catheter and guidewire with threaded tip connection
CN102107041A (en) * 2009-12-25 2011-06-29 朝日英达科株式会社 Guidewire
EP2402051A1 (en) * 2010-06-30 2012-01-04 PatentStra Co. Ltd. Medical guide wire

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5489983B2 (en) * 2008-03-27 2014-05-14 テルモ株式会社 Guide wire
US8777873B2 (en) 2008-06-13 2014-07-15 Cook Medical Technologies Llc Wire guide having a rib for coil attachment
WO2010134364A1 (en) * 2009-05-20 2010-11-25 日本ライフライン株式会社 Medical guide wire
WO2012009518A1 (en) * 2010-07-16 2012-01-19 Neurointerventional Therapeutics, Inc. Guidewire and catheter system and method for treating a blood clot

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5409470A (en) * 1993-05-07 1995-04-25 C. R. Bard, Inc. Dilatation catheter and guidewire with threaded tip connection
CN102107041A (en) * 2009-12-25 2011-06-29 朝日英达科株式会社 Guidewire
EP2402051A1 (en) * 2010-06-30 2012-01-04 PatentStra Co. Ltd. Medical guide wire

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HK1200746A1 (en) 2015-08-14
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WO2013145893A1 (en) 2013-10-03
KR20140141605A (en) 2014-12-10
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KR101844630B1 (en) 2018-04-02
JP2013202308A (en) 2013-10-07

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