CN104023783A - Medical guide wire - Google Patents

Medical guide wire Download PDF

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Publication number
CN104023783A
CN104023783A CN201380004444.6A CN201380004444A CN104023783A CN 104023783 A CN104023783 A CN 104023783A CN 201380004444 A CN201380004444 A CN 201380004444A CN 104023783 A CN104023783 A CN 104023783A
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CN
China
Prior art keywords
resin
helical spring
heart yearn
rear end
wire
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201380004444.6A
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Chinese (zh)
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CN104023783B (en
Inventor
奥村亮一
河崎浩范
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japan Lifeline Co Ltd
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Japan Lifeline Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Publication of CN104023783A publication Critical patent/CN104023783A/en
Application granted granted Critical
Publication of CN104023783B publication Critical patent/CN104023783B/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09Guide wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09Guide wires
    • A61M2025/09058Basic structures of guide wires
    • A61M2025/09083Basic structures of guide wires having a coil around a core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09Guide wires
    • A61M2025/09166Guide wires having radio-opaque features

Abstract

A medical guide wire has: a core wire (10) having a distal end small-diameter section (11) and a proximal end large-diameter section (14); and a coiled spring (20) mounted to the outer periphery of the distal end small-diameter section (11). The coiled spring (20) comprises: a front end closely wound section (21) having a pitch which is 1.0 to 1.8 times the diameter of the coil wire; and a rear end loosely wound section (22) having a pitch which is 1.8 to 2.5 times the diameter of the coil wire. The inside of the rear end loosely wound section (22) is filled with a resin (40), and a resin layer (40A) consisting of the resin is formed on the outer periphery of the rear end loosely wound section (22). A hydrophilic resin coating layer (50) is laminated and formed on the surface of the resin layer (40A). The outer periphery of the front end closely wound section (21) is not coated with a resin, and a material which forms the coiled spring (20) is exposed at the outer periphery. The guide wire has satisfactory lubricating properties at the distal end thereof, has satisfactory insertability, enables information within a blood vessel to be sufficiently sensed as resistance (change) by the operator's hand, and can be reliably advanced to a destination site.

Description

Medical guide wire
Technical field
The present invention relates to have the helical spring medical guide wire in the periphery of the distolateral minor diameter part of amphi position that is installed on heart yearn.
Background technology
For for the wire towards endoceliac assigned position guiding such as blood vessels by medical apparatus such as conduits (catheter), require pliability, the flexibility of amphi position end.
Therefore, known following such wire, it makes the external diameter of amphi position end of heart yearn less than the external diameter of peri position end, and the periphery in the amphi position end of heart yearn (the distolateral minor diameter part of amphi position) is installed helical spring, thereby attempt improves the pliability (referring to Patent Document 1) of amphi position end.
In addition, introduction has in the helical spring inside of the amphi position end that is installed on heart yearn and is filled with resin, and be formed with the resin bed by above-mentioned resin formation in helical spring periphery, at the stacked wire (referring to Patent Document 2) that is formed with hydrophilic resin layer in the surface of this resin bed.By forming hydrophilic resin layer in helical spring periphery, can give lubricity to the amphi position end of wire, thereby can improve the insertion of wire.
Patent documentation 1: TOHKEMY 2003-299739 communique
Patent documentation 2: TOHKEMY 2010-214054 communique
For example, for the endovascular information (, the situation of the diseased regions such as narrow, occlusive part) that is inserted with wire, operator is by feeling that by feel the resistance (variation) of the vascular site that the amphi position end of wire contacts grasps.
But, as the wire that above-mentioned patent documentation 2 is recorded, for cover the wire that is formed with hydrophilic resin layer in helical spring periphery for, almost experience less than resistance as described above (variation), therefore make the grasp of information become difficulty.
In addition, though such wire obtains good lubricity, its amphi position end of another side becomes easy slip, is therefore difficult to wire to advance towards object position.
And, owing to almost experiencing less than resistance (variation), so that must apply front end load more than desirable value, thereby have the worry that blood vessel is caused to damage.
On the other hand, for example, in the time of the interpolation admittance line of the microchannel in CTO pathological changes (microchannel), being undertaken the fore-end bending of wire to formalize by operator (is shaped: operation shaping).
But, as the wire that above-mentioned patent documentation 2 is recorded, for be filled with the wire of resin in helical spring inside for, because the resin of filling at fore-end is difficult to form operation.
Summary of the invention
The situation of the present invention based on above produces.
The object of the present invention is to provide a kind of medical guide wire, it has good lubricity in amphi position end, the insertion of wire is good, and can be using endovascular information as resistance (variation) and grasp fully in hands side, and the medical guide wire that can advance towards object position reliably.
Other objects of the present invention are to provide a kind of medical guide wire that can more easily form operation.
(1) medical guide wire of the present invention has: heart yearn, and it has the distolateral minor diameter part of amphi position and the external diameter peri position distolateral large-diameter portion larger than the distolateral minor diameter part of above-mentioned amphi position; And
Helical spring, it is along the periphery of the distolateral minor diameter part of amphi position that is axially installed on above-mentioned heart yearn, and is at least fixed on above-mentioned heart yearn at leading section and rearward end,
Above-mentioned medical guide wire is characterised in that,
It is that the sparse winder of rear end side of 1.8~2.5 times of coil wire diameter forms that the front of 1.0~1.8 times that above-mentioned helical spring is coil wire diameter by coil pitch is closely wound portion and coil pitch,
Inside in the sparse winder of above-mentioned rear end side is filled with resin, and is formed with the resin bed by above-mentioned resin formation in the periphery of the sparse winder of above-mentioned rear end side, at the stacked hydrophilic resin cover layer that is formed with in the surface of above-mentioned resin bed,
The periphery that above-mentioned front is closely wound portion is not covered by resin, but exposes above-mentioned helical spring constituent material.
According to the medical guide wire of such structure, the periphery that front is closely wound portion is not covered by resin, but expose helical spring constituent material, thereby the endovascular information that is inserted with wire can be grasped to (information transitivity is superior) fully in hands side as resistance (variation).
In addition, owing to can grasping fully the information of the vascular site that the front portion of being closely wound contacts, and the front portion of being closely wound is difficult to slide, so medical guide wire of the present invention can be advanced to (directional selectivity of wire is superior) reliably towards endovascular object position.
In addition, by being filled with resin in the inside of the sparse winder of rear end side, can make heart yearn and helical spring (the sparse winder of rear end side) integrated, thereby can improve moment of torsion transitivity, the operability (moment of torsion transitivity is superior) of wire.
In addition, owing to being formed with resin bed in the periphery of the sparse winder of rear end side, at the stacked hydrophilic resin cover layer that is formed with in the surface of this resin bed, so have hydrophilic resin cover layer via the resin bed of the resin formation by identical with the inside that is filled in the sparse winder of rear end side at the periphery stratification of the sparse winder of rear end side, therefore hydrophilic resin cover layer can be fixed reliably, and can stably manifest the preferred lubricity (hydrophilic resin cover layer is superior with respect to the close property of the periphery of the sparse winder of rear end side) of hydrophilic resin.
(2), in medical guide wire of the present invention, the inside that is preferably closely wound portion in above-mentioned front is not filled with resin.
According to such structure, can guarantee fully that front is closely wound the pliability of portion, flexibility, in helical spring (front is closely wound portion), can easily form operation.
(3) in medical guide wire of the present invention, the external diameter (D of the distolateral large-diameter portion of peri position of preferred above-mentioned heart yearn 1) and above-mentioned helical spring coil outer diameter (D 2) below 0.012 inch,
Above-mentioned helical spring length (L 2) be 51~800mm,
Above-mentioned front is closely wound the length (L of portion 21) be 1~50mm,
Length (the L of the sparse winder of above-mentioned rear end side 22) be 50~750mm.
(4) in medical guide wire of the present invention, preferably include above-mentioned helical spring front and be closely wound portion and the sparse winder of rear end side at interior pars intermedia, be fixed on above-mentioned heart yearn by solder.
(5), in the medical guide wire of above-mentioned (4), preferably above-mentioned helical spring leading section and pars intermedia, by being fixed on above-mentioned heart yearn containing gold brazing filler metal.
(6), in medical guide wire of the present invention, preferred above-mentioned heart yearn is made up of rustless steel.
According to medical guide wire of the present invention, there is good lubricity in amphi position end, and the property inserted is good, and can be using endovascular information as resistance (variation) and grasp fully in hands side, and can advance reliably towards object position.
In addition, by being filled with resin in the inside of the sparse winder of rear end side, make moment of torsion transitivity superior.
In addition, according to the medical guide wire of the present invention that possesses the front that is not filled with resin in inside and be closely wound portion, can more easily form operation.
Brief description of the drawings
A part for an embodiment that represents wire of the present invention is dissectd the side view forming by Fig. 1.
A part for an embodiment that represents wire of the present invention is dissectd the side view (for the figure that size is described) forming by Fig. 2.
Detailed description of the invention
Wire 1 shown in Fig. 1 and Fig. 2 is a kind of medical guide wire, and it has: heart yearn 10, and it has the distolateral minor diameter part 11 of amphi position and the external diameter peri position distolateral large-diameter portion 14 larger than the distolateral minor diameter part 11 of amphi position, and helical spring 20, it is along the periphery of the distolateral minor diameter part 11 of the amphi position that is axially installed on heart yearn 10, and at leading section, pars intermedia and rearward end are fixed on heart yearn 10, the front of 1.0~1.8 times that helical spring 20 is coil wire diameter by coil pitch is closely wound portion 21, the sparse winder 22 of the rear end side of 1.8~2.5 times that is coil wire diameter with coil pitch forms, inside in the sparse winder 22 of rear end side is filled with cured resin 40, and be formed with the resin bed 40A being formed by this cured resin in the periphery of the sparse winder 22 of rear end side, at the stacked hydrophilic resin cover layer 50 that is formed with in the surface of resin bed 40A, on the other hand, the periphery that front is closely wound portion 21 is not covered by resin, but expose the constituent material of helical spring 20, and the inside that is closely wound portion 21 in front is not also by resin filling.
The wire 1 of present embodiment has heart yearn 10 and helical spring 20.Heart yearn 10 has the distolateral minor diameter part 11 of amphi position to have carried out from taper processing to the mode of peri position direction hole enlargement, tapered portion 13 and the distolateral large-diameter portion 14 of peri position to the hole enlargement of peri position direction.
The distolateral minor diameter part 11 of amphi position, tapered portion 13 and the distolateral large-diameter portion 14 of peri position for example, are made up of same wire rod (, pole parts) one.
The cross section of the distolateral large-diameter portion 14 of tapered portion 13 and peri position is circular.
The distolateral cross section of peri position of the distolateral minor diameter part 11 of amphi position is circular, also wire rod compression can be become tabularly but the amphi position of the distolateral minor diameter part 11 of amphi position is distolateral, and the cross section in this situation becomes essentially rectangular.
Material as heart yearn 10 is not particularly limited, and such as, though can list the metals such as rustless steel (SUS316, SUS304), gold, platinum, aluminum, tungsten, tantalum or these alloy, in the present embodiment, is made up of rustless steel.
In addition, be formed with hydrophobicity resin layer (omitting diagram) at the outer peripheral face of heart yearn 10.
Be as resin medical and that use as the resin that forms hydrophobicity resin layer, can use the whole medical resin with hydrophobicity, as preferred resin, can list the fluororesin such as PTFE.
Total length (the L of the wire 1 shown in Fig. 2 1) be for example 1500~3000mm, if a preferred example is shown, be 1780mm.
In addition, the external diameter (D of the distolateral large-diameter portion 14 of peri position 1) conventionally below 0.012 inch (0.305mm), preferably, below 0.010 inch (0.254mm), more preferably 0.006~0.010 inch, if a preferred example is shown, be 0.010 inch.
External diameter (the D of the distolateral large-diameter portion 14 of peri position 1) below 0.012 inch, therefore can contribute to and the miniaturization of the medical apparatus such as the common conduit using of wire of the present invention, and then can contribute to Wicresoft.
As the maximum outside diameter of the distolateral minor diameter part 11 of amphi position, as long as less than the internal diameter of helical spring 20, be not particularly limited, but be formed as the external diameter (D of the distolateral large-diameter portion 14 of peri position 1) 1/5~3/5 left and right.
Form the helical spring 20 of the wire 1 of present embodiment, along the periphery of the distolateral minor diameter part 11 of the amphi position that is axially installed on heart yearn 10.
Helical spring 20 is formed by a wire rod, and it is that the sparse winder 22 of the rear end side of 1.8~2.5 times of coil wire diameter forms that the front of 1.0~1.8 times that is coil wire diameter by coil pitch is closely wound portion 21 and coil pitch, is closely wound portion 21 and front end point described later by front and forms X ray and do not see through region.
The coil pitch that front is closely wound portion 21 is 1.0~1.8 times of coil wire diameter, if a preferred example is shown, is 1.0 times.
The coil pitch of the sparse winder 22 of rear end side is 1.8~2.5 times of coil wire diameter, if a preferred example is shown, is 2.0 times.
Like this, by front and rear end side, coil pitch being changed, can be closely wound portion 21 in front and manifest good radiography (visuality).
Whole region at helical spring 20 is formed as same pitch, because X ray is elongated through region, causes visual reduction.
Coil outer diameter (the D of helical spring 20 2) conventionally below 0.012 inch (0.305mm), preferably, below 0.010 inch (0.254mm), more preferably 0.006~0.010 inch, if a preferred example is shown, be 0.010 inch.
External diameter (the D of the distolateral large-diameter portion 14 of peri position of heart yearn 10 1) below 0.012 inch, and the coil outer diameter (D of helical spring 20 2) also below 0.012 inch, the operability (for example, the lubricity of microchannel) while therefore entering to microchannel is superior.
Being not particularly limited though form the external diameter of the wire rod of helical spring 20, being preferably 30~90 μ m, if a preferred example is shown, is 60 μ m.
As the material of helical spring 20, can list the materials (X ray not penetrating material) good to the radiography of X ray such as platinum, White gold alloy (such as Pt/W=92/8), gold, gold-copper alloy, tungsten, tantalum.
For the wire 1 of present embodiment, leading section, rearward end and the pars intermedia of helical spring 20 (front is closely wound the boundary member of portion 21 and the sparse winder 22 of rear end side) utilize respectively solder 31,32,33 and are fixed on the periphery of the distolateral minor diameter part 11 of amphi position of heart yearn 10.
As shown in Figure 1, the leading section of helical spring 20 is fixed on heart yearn 10 by solder 31.That is, solder 31 soaks in the inside of helical spring 20, and this solder 31 contacts with the periphery of heart yearn 10 (the distolateral minor diameter part 11 of amphi position), thereby the leading section of helical spring 20 is fixed on to heart yearn 10.
In addition, at the leading section of helical spring 20, form roughly hemispheric front end point by not soaking in the solder 31 of the inside of helical spring 20.Thus, at the leading section of wire, form the hard straight part of the front end that formed by solder 31 (by because soaking in the hard straight part that the solder 31 of coil inside becomes the fore-end of helical spring 20 that cannot free bend and the front end point that formed by this solder 31 forms).
In addition, comprise that the front of helical spring 20 is closely wound the pars intermedia of the borderline region of portion 21 and the sparse winder 22 of rear end side, is fixed on heart yearn 10 by solder 32.That is, solder 32 soaks in the inside of helical spring 20, and this solder 32 contacts with the periphery of heart yearn 10 (the distolateral minor diameter part 11 of amphi position), thereby the pars intermedia of helical spring 20 is fixed on to heart yearn 10.
And the rearward end of helical spring 20 is fixed on heart yearn 10 by solder 33.That is, solder 33 soaks in the inside of helical spring 20, and this solder 33 contacts with the periphery of heart yearn 10 (the distolateral minor diameter part 11 of amphi position), thereby the rearward end of helical spring 20 is fixed on to heart yearn 10.
As the solder 31,32 for the leading section of helical spring 20 and pars intermedia being fixed on respectively to heart yearn 10, preferably use containing gold brazing filler metal.
By using as solder 31,32 containing gold brazing filler metal, can make constant intensity enough high (fracture strength than the amphi position of heart yearn 10 distolateral minor diameter part 11 higher) of helical spring 20 with respect to heart yearn 10, even the heart yearn 10 under the state of insertion helical spring 20 is applied to tensile force, heart yearn 10 also can not be pulled out." contain gold brazing filler metal " herein, and comprise Au solder alloy and the Au solders such as Au-Sn brazing filler metal, Au-Ge brazing filler metal, Au-Si brazing filler metal, Au-In brazing filler metal, Au-Sb brazing filler metal.
On the other hand, as the solder 33 for the rearward end of helical spring 20 being fixed on to heart yearn 10, can illustrate the silver-colored brazing filler metals such as Ag-Sn system.
As shown in Figure 1, in the wire 1 of present embodiment, inside in the sparse winder 22 of rear end side of helical spring 20 is filled with cured resin 40, and be formed with the resin bed 40A (covering the layer of the cured resin of coil wire rod) being formed by this cured resin 40 in the periphery of the sparse winder 22 of rear end side, at the stacked hydrophilic resin cover layer 50 that is formed with in the surface of this resin bed 40A.
Inside in the sparse winder 22 of rear end side of helical spring 20 is filled with cured resin 40, thereby make heart yearn 10 and helical spring 20 integrated, the moment of torsion transitivity of wire is significantly improved, and the rotation torque that distolateral peri position from heart yearn 10 large-diameter portion 14 is transmitted is passed to the amphi position end with the integrated helical spring 20 of the distolateral minor diameter part 11 of amphi position reliably.
In addition, periphery in the sparse winder 22 of rear end side of helical spring 20 is formed with resin bed 40A, at the stacked hydrophilic resin cover layer 50 (periphery in the sparse winder 22 of rear end side is formed with hydrophilic resin cover layer 50 via resin bed 40A) that is formed with in the surface of this resin bed 40A, therefore hydrophilic resin cover layer 50 is firmly fixed at helical spring 20, thus, can stably show the suitable lubricity of hydrophilic resin.
Herein, as being filled in the inside of the sparse winder 22 of rear end side and the cured resin 40 of formation resin bed 40A, preferably with respect to helical spring 20 and hydrophilic resin, the two all has good fusible cured resin, particularly, can exemplify: the solidfied material of the light-cured resins such as polyurethane acrylate resin, polyurethane resin, silicone resin, epoxy resin, acrylic resin, nylon resin or heat-curing resin etc.
As the thickness of resin bed 40A of periphery that covers rear end side sparse winder 22, be for example 1~100 μ m, be preferably 3~10 μ m.
As the hydrophilic resin that forms the stacked surperficial hydrophilic resin cover layer 50 that is formed at resin bed 40A, can use the known hydrophilic polymer in the past for the hydrophilic processing of medical instruments.Particularly can exemplify: the polysaccharides such as Polyethylene Glycol, polyethylene glycol oxide, polyhydric alcohol, polyacrylamide, polyvinyl pyrrolidone, polyvinyl alcohol, polyethers, polyurethane, polycarboxylic acids and these derivant, cellulose, protein, hyaluronic acid.In addition, these hydrophilic polymeies also can have the structure of bridge formation.
As the thickness of hydrophilic resin layer 50, be for example 1~30 μ m, be preferably 3~19 μ m.
As the filling of cured resin 40 and the formation method of resin bed 40A, and the stratification method of hydrophilic resin 50 is not particularly limited, for example can enumerate following method: the sparse winder 22 of rear end side of the helical spring 20 that is installed on heart yearn 10 be impregnated in to curable resin, thereby curable resin is filled in the inside in the sparse winder 22 of rear end side, form resin bed on the surface of the sparse winder 22 of rear end side simultaneously, by its heat cure or photocuring are become to cured resin 40 (resin bed 40A), then, utilize suitable method, at the surface-coated hydrophilic resin of resin bed 40A.
At this, in the situation that front being closely wound to portion 21 and jointly impregnated in curable resin with the sparse winder 22 of rear end side, the periphery that preferably front is closely wound to portion 21 hides etc., prevents that inside and periphery that curable resin is closely wound portion 21 towards front from flowing into and adhering to.
As shown in Figure 1, in the wire 1 of present embodiment, the periphery that the front of helical spring 20 is closely wound portion 21 is not covered by resin, but exposes the constituent material (X ray is the metal such as penetrating material not) of helical spring 20.
Thus, the endovascular information (for example, the situation of the diseased region such as narrow, occlusive part) of the wire 1 that is inserted with present embodiment can be grasped in hands side fully as resistance (variation).
In addition, can grasp fully the information that front is closely wound the vascular site that portion 21 contacts, and the front not covered by hydrophilic resin is closely wound portion 21 and is difficult for sliding, and therefore can reliably the wire of present embodiment 1 be advanced towards endovascular object position.
In addition, in the wire 1 of present embodiment, the inside that is closely wound portion 21 in front is not filled with resin.Thus, can guarantee fully that front is closely wound the pliability of portion 21, flexibility, form operation thereby can easily be closely wound portion 21 in front.
In addition,, even if the inside that is closely wound portion 21 in front is not filled with resin, also can fill cured resin 40 and guarantee fully by the inside in the sparse winder 22 of rear end side the moment of torsion transitivity of wire 1.
Length (the L of the helical spring 20 shown in Fig. 2 2) being preferably 51~800mm, more preferably 85~310mm, if a preferred example is shown, is 115mm.
Front is closely wound the length (L of portion 21 21) being preferably 1~50mm, more preferably 20~40mm, if a preferred example is shown, is 30mm.
Length (the L of the sparse winder 22 of rear end side 22) being preferably 50~750mm, more preferably 65~270mm, if a preferred example is shown, is 85mm.
Be closely wound the length (L of portion 21 in the front of covering resin not 21) in too small situation, cannot grasp fully the endovascular information that is inserted with wire, in addition, the amphi position end of wire becomes easy slip, thereby is difficult to such wire to advance towards object position.
On the other hand, be closely wound the length (L of portion 21 in front 21) in excessive situation, the lubricity deficiency of the amphi position end of wire, so that be for example difficult to make wire by narrow positions etc., thus damage the insertion of wire.
In addition, at the length (L of the sparse winder 22 of rear end side 22) in too small situation, the lubricity of the amphi position end of wire is not enough and damage the insertion of wire.In addition, sometimes damage the moment of torsion transitivity of wire.
On the other hand, at the length (L because of the sparse winder 22 of rear end side 22) excessive and cause front to be closely wound the length (L of portion 21 21) in relatively too small situation, cannot grasp fully the endovascular information that is inserted with wire, in addition, be difficult to wire to advance towards object position.
Length (the L of the roughly hemispheric front end point being formed by solder 31 3) be for example 0.1~5.0mm, if a preferred example is shown, be 0.3mm.
As described above, according to the wire 1 of present embodiment, there is good lubricity in the amphi position end that helical spring 20 (the sparse winder 22 of rear end side) is installed, and good towards endovascular insertion, and the periphery that front is closely wound portion 21 is not covered by resin, but expose the constituent material (metal) of helical spring 20, thereby can be using endovascular information as resistance (variation) and grasp fully in hands side, and can advance towards object position reliably.
In addition, owing to being filled with cured resin 40 in the inside of the sparse winder 22 of rear end side, so moment of torsion transitivity is superior.
In addition, because the inside that is closely wound portion 21 in front is not filled with resin, therefore can easily form operation.
Description of reference numerals
10... heart yearn; 11... the distolateral minor diameter part of amphi position; 13... tapered portion; 14... the distolateral large-diameter portion of peri position; 20... helical spring; 21... front is closely wound portion; 22... the sparse winder of rear end side; 31... solder; 32... solder; 33... solder; 40... cured resin; 40A... resin bed; 50... hydrophilic resin layer.

Claims (6)

1. a medical guide wire,
Have:
Heart yearn, it has the distolateral minor diameter part of amphi position and the external diameter peri position distolateral large-diameter portion larger than the distolateral minor diameter part of described amphi position; And
Helical spring, it is along the periphery of the distolateral minor diameter part of amphi position that is axially installed on described heart yearn, and is at least fixed on described heart yearn at leading section and rearward end,
Described medical guide wire is characterised in that,
It is that the sparse winder of rear end side of 1.8~2.5 times of coil wire diameter forms that the front of 1.0~1.8 times that described helical spring is coil wire diameter by coil pitch is closely wound portion and coil pitch,
Inside in the sparse winder of described rear end side is filled with resin, and is formed with the resin bed by described resin formation in the periphery of the sparse winder of described rear end side, at the stacked hydrophilic resin cover layer that is formed with in the surface of described resin bed,
The periphery that described front is closely wound portion is not covered by resin, but exposes described helical spring constituent material.
2. medical guide wire according to claim 1, is characterized in that,
The inside that is closely wound portion in described front is not filled with resin.
3. medical guide wire according to claim 1 and 2, is characterized in that,
External diameter (the D of the distolateral large-diameter portion of peri position of described heart yearn 1) and described helical spring coil outer diameter (D 2) below 0.012 inch,
Described helical spring length (L 2) be 51~800mm,
Described front is closely wound the length (L of portion 21) be 1~50mm,
Length (the L of the sparse winder of described rear end side 22) be 50~750mm.
4. according to the medical guide wire described in any one in claim 1~3, it is characterized in that,
Pars intermedia including described helical spring front is closely wound portion and the sparse winder of rear end side, is fixed on described heart yearn by solder.
5. medical guide wire according to claim 4, is characterized in that,
Described helical spring leading section and pars intermedia, by being fixed on described heart yearn containing gold brazing filler metal.
6. according to the medical guide wire described in any one in claim 1~5, it is characterized in that,
Described heart yearn is made up of rustless steel.
CN201380004444.6A 2012-03-29 2013-02-08 Medical guide wire Active CN104023783B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012-077045 2012-03-29
JP2012077045A JP5404840B2 (en) 2012-03-29 2012-03-29 Medical guidewire
PCT/JP2013/053077 WO2013145893A1 (en) 2012-03-29 2013-02-08 Medical guide wire

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CN104023783A true CN104023783A (en) 2014-09-03
CN104023783B CN104023783B (en) 2016-01-20

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JP (1) JP5404840B2 (en)
KR (1) KR101844630B1 (en)
CN (1) CN104023783B (en)
HK (1) HK1200746A1 (en)
TW (1) TWI517869B (en)
WO (1) WO2013145893A1 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
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CN107847716A (en) * 2015-11-17 2018-03-27 郡是株式会社 Medical guide wire
CN108064179A (en) * 2016-09-05 2018-05-22 朝日英达科株式会社 Seal wire
CN109562246A (en) * 2016-08-12 2019-04-02 黑博尔激光精密技术有限两合公司 Apply the guide wire in the blown tubular medical probe especially for nutrition physical therapy
CN110831532A (en) * 2017-06-29 2020-02-21 朝日英达科株式会社 Guide wire for plasma
CN111405923A (en) * 2018-02-01 2020-07-10 朝日英达科株式会社 Guide wire

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CN102107041A (en) * 2009-12-25 2011-06-29 朝日英达科株式会社 Guidewire
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WO2009119386A1 (en) * 2008-03-27 2009-10-01 テルモ株式会社 Guide wire
CN102107041A (en) * 2009-12-25 2011-06-29 朝日英达科株式会社 Guidewire
EP2402051A1 (en) * 2010-06-30 2012-01-04 PatentStra Co. Ltd. Medical guide wire
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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107847716A (en) * 2015-11-17 2018-03-27 郡是株式会社 Medical guide wire
CN109562246A (en) * 2016-08-12 2019-04-02 黑博尔激光精密技术有限两合公司 Apply the guide wire in the blown tubular medical probe especially for nutrition physical therapy
CN108064179A (en) * 2016-09-05 2018-05-22 朝日英达科株式会社 Seal wire
CN110831532A (en) * 2017-06-29 2020-02-21 朝日英达科株式会社 Guide wire for plasma
CN110831532B (en) * 2017-06-29 2023-03-21 朝日英达科株式会社 Guide wire for plasma
CN111405923A (en) * 2018-02-01 2020-07-10 朝日英达科株式会社 Guide wire

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WO2013145893A1 (en) 2013-10-03
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KR101844630B1 (en) 2018-04-02
JP2013202308A (en) 2013-10-07

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