CN103861195B - Trans-radial gets involved superslide seal wire - Google Patents
Trans-radial gets involved superslide seal wire Download PDFInfo
- Publication number
- CN103861195B CN103861195B CN201210570427.6A CN201210570427A CN103861195B CN 103861195 B CN103861195 B CN 103861195B CN 201210570427 A CN201210570427 A CN 201210570427A CN 103861195 B CN103861195 B CN 103861195B
- Authority
- CN
- China
- Prior art keywords
- wire
- seal wire
- nuclear core
- wrapping
- core silk
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09058—Basic structures of guide wires
- A61M2025/09083—Basic structures of guide wires having a coil around a core
- A61M2025/09091—Basic structures of guide wires having a coil around a core where a sheath surrounds the coil at the distal part
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09175—Guide wires having specific characteristics at the distal tip
Abstract
The open a kind of trans-radial of the present invention gets involved superslide seal wire, and this seal wire includes: nuclear core silk, is positioned at the internal layer of seal wire；Wrapping wire, is positioned at the intermediate layer of seal wire and covers whole nuclear core silk, and wherein, the near-end of nuclear core silk is connected with the near-end of wrapping wire, and the far-end of nuclear core silk is in free state；And sheath, it is positioned at the outer layer of seal wire and covers the major part of wrapping wire.Compared with prior art, the present invention solves in trans-radial intervention diagnosis and treatment operation process that superslide seal wire supportive is poor, sense of touch feed back not good enough, be easily caused blood vessel injury, cannot the most repeatedly enter the problems such as conduit, improve the combination property of radiography seal wire comprehensively.
Description
Technical field
The present invention relates to single use medical instruments field, specifically, relate to a kind of use
In Percutantnoeus coronary intervention diagnosis and treatment operation, particularly during trans-radial approach, it is achieved examine
Break and treat conduit guiding in human body and the superslide seal wire of positioning action.
Background technology
Percutaneous coronary is got involved and is referred to through catheter diagnosis degree of stenosis and carry out phase
The diagnosis that should process and Therapeutic Method.At present, Percutantnoeus coronary intervention diagnosis and treatment are performed the operation
Get involved path main share split tremulous pulse and radial artery.1989, Canada doctor Campeau was first
Wound Experience of Transradial carries out coronarography, Dutch doctor Kiemenij report in 1992
Accuse and used this approach to carry out the result treated.Along with Percutantnoeus coronary intervention diagnosis and treatment hands
Art popularizing in the world, trans-radial carries out Percutantnoeus coronary intervention by extensively
Be applied to clinical crown cardiopathia intervention diagnosis and treatment, and with its damage is little, Local Complications is few,
Perioperatively limits tube drawing immediately little, postoperative to anticoagulant, antiplatelet drug and need not force
Lie in bed 24 hours wait more " Wicresoft " advantage and extremely patient and get involved doctor favor.Mesh
Front China carries out Percutantnoeus coronary intervention diagnosis by radial artery path every year and treatment has been performed the operation
More than 500,000 examples.
In percutaneous coronary intervention diagnosis and treatment operation, radiography seal wire is a kind of important
Apparatus, for angiography catheter being imported Ink vessel transfusing and resting on the position specified.Seal wire
Properties (such as: the holding power of seal wire, the compliance of seal wire, the propelling movement power etc. of seal wire)
It is whole to get involved the key factor that is smoothed out of operation.
The most modal radiography seal wire has traditional stainless steel silk be wound around seal wire and surpass
Sliding seal wire (being commonly called as Misgurni anguillicaudati seal wire).Stainless steel silk is wound around seal wire and uses helical spring to be wound around core
The form of silk, its head end is relatively big without reducing, hardness, compliance is poor, not easily pass through flexibility
Bigger blood vessel.Additionally, conventional guide wires head end is without reducing, its head end is also made to be relatively large in diameter,
Seal wire is relatively big with blood vessel wall frictional force in intervention procedure, push difficulty, be prone to cause blood vessel
Spasm.Superslide seal wire has good smoothness because of it, substantially reduces the propelling movement power of seal wire
And there is the strongest handling capacity, it is thus achieved that the accreditation of more and more doctors.But, superslide
Seal wire does not uses or local uses the spring wrapping wire of conventional guide wires to design, surface
The structure using polymer jacket to add hydrophilic coating all covers, and its surface is the most smooth,
Operator's feel is not good enough, and high smoothness causes the loss of sense of touch feedback, at intervention diagnosis and
Blood vessel injury is easily caused during treatment.The lighter causes the hemorrhage complications such as local hematoma, severe one
Osteofascial compartment syndrome is caused to jeopardize patient vitals.According to statistics, have at present 5%～8% through oar
Tremulous pulse diagnosis and treatment operative hemorrhage complication are directly or indirectly caused by superslide seal wire, superslide
The use of seal wire increases operation risk, causes unnecessary misery for patient.
At present, in superslide seal wire common on market, straight type can be divided into common by head end shape
Superslide seal wire and J-type elbow superslide seal wire.The former have brilliance by performance, but its table
Face is the most smooth, is easily caused blood vessel injury during pushing.The latter is due to its head end
Bending, adds buffering, effectively reduces the damage to blood vessel during pushing.But J
Type seal wire after a procedure, owing to head end can not be made by the way of push-and-pull to straighten, it has not been convenient to again
Secondary entrance conduit, adds the fussy degree of operation.In sum, current superslide seal wire
Performance remains in open defect, possesses the biggest room for improvement.
The present situation of the performance according to above-mentioned Cardiac interventional class superslide seal wire, the deficiency being primarily present
It is: 1) use polymer jacket while improving smoothness, reduce other property of product
Can, mainly reduce seal wire supportive and safety, have impact on the feel of operator, increase
Add the risk of blood vessel injury；2) although J-type elbow superslide seal wire can reduce blood vessel injury
Risk, but be inconvenient to be again introduced into conduit, add the fussy degree of operation.
Summary of the invention
Present invention seek to address that the above-mentioned one or more problems mentioned, it is provided that one can be
Trans-radial intervention diagnosis and treatment operation process have good combination property and can repeatedly enter
Enter the superslide seal wire of conduit.
According to an aspect of the present invention, it is provided that a kind of seal wire, including nuclear core silk, this nuclear core
Silk is positioned at the internal layer of seal wire；Wrapping wire, this wrapping wire is positioned at the intermediate layer of seal wire and covers whole
Nuclear core silk, wherein, the near-end of nuclear core silk is connected with the near-end of wrapping wire, the far-end of nuclear core silk
In free state；And sheath, this sheath is positioned at the outer layer of seal wire and covers the big of wrapping wire
Part.
Preferably, seal wire also includes safe core filaments, and this safe core filaments is positioned at nuclear core silk and wrapping wire
Between, safe core filaments the most respectively with being proximally and distally connected of wrapping wire.
Preferably, seal wire also includes coating, and this coating is applied on the surface of sheath.
Preferably, the distal end tapers down of nuclear core silk.
Preferably, wrapping wire is helical spring wrapping wire.
Preferably, the part not covered by sheath of wrapping wire is positioned at the subregion in the middle part of seal wire,
The camber of guidewire distal region can be manipulated by this part wrapping wire of push-and-pull.
Preferably, the part not covered by sheath of wrapping wire is positioned at the proximal end region of seal wire, logical
Cross this part wrapping wire of push-and-pull and can manipulate the camber of guidewire distal region.
Preferably, safe core filaments is flat and the side being positioned at nuclear core silk.
Preferably, nuclear core silk uses Nitinol, rustless steel, Ti-Nb alloy, Ti-Ni-X
Alloy, Cu-Zn alloy, Cu-Zn-Ni alloy, Fe-Ni alloy/C or Fe-Mn alloy manufacture.
Preferably, safe core filaments is stainless steel silk.
Preferably, sheath is polymer jacket.
Preferably, coating is Teflon, PVP, polyethylene, polypropylene, polrvinyl chloride, gathers
Ester, polyamide, polyimides, polyurethanes, polystyrene, Merlon, silicon
Resin, fluor resin coating or include the composite coating of described any combination thereof.
Preferably, the near-end of nuclear core silk welds together with the near-end of wrapping wire.
Preferably, safe core filaments the most respectively with proximally and distally the welding of wrapping wire
Together.
According to a further aspect in the invention, it is provided that a kind of use can enter leading of conduit repeatedly
The method of silk, including:
Above-mentioned seal wire is provided；
The far-end making seal wire enters in conduit and pushes seal wire；
When needed, by pulling the part not covered by sheath of described wrapping wire so that lead
Silk remote area bending, to pass through bending channel；
When operation completes, extract seal wire out；
By promoting the part not covered by sheath of described wrapping wire so that guidewire distal region
Straighten, so that the far-end of seal wire can be again introduced into conduit.
Compared with prior art, the present invention solves trans-radial intervention diagnosis and treatment operation
During superslide seal wire supportive is poor, sense of touch feedback is not good enough, be easily caused blood vessel injury, nothing
Method enters the problems such as conduit the most repeatedly, improves the combination property of radiography seal wire comprehensively.
Accompanying drawing explanation
Fig. 1 is the Longitudinal cross section schematic of the seal wire according to one embodiment of the present invention；
Fig. 2 is that the remote area of seal wire is from bending the process schematic straightened；
Fig. 3 is that after seal wire is drawn out of, its remote area straightens process schematic；And
Fig. 4 is the Longitudinal cross section schematic of the seal wire according to another embodiment of the invention.
Detailed description of the invention
In this manual, same reference is used for representing same ingredient.
Fig. 1 is the Longitudinal cross section schematic of the seal wire according to one embodiment of the present invention.Ginseng
According to Fig. 1, seal wire mainly includes nuclear core silk 1, wrapping wire 2 and sheath 3.Below will for this three
Each in individual part is described in detail.
Nuclear core silk 1 is positioned at the internal layer of seal wire, its circular in cross-section or any other is suitable
Shape.The far-end of nuclear core silk 1 uses reducing to process, and is preferably tapered, the most permissible
The far-end making seal wire has more preferable compliance, reduces far-end hardness and improve the propelling movement of seal wire
Performance.Nuclear core silk 1 can use Nitinol, rustless steel, Ti-Nb alloy, Ti-Ni-X
Alloy, Cu-Zn alloy, Cu-Zn-Ni alloy, Fe-Ni alloy/C or Fe-Mn alloy etc. have
The material of excellent in shape memory ability is made, thus provides good holding power for seal wire.
Wrapping wire 2 is positioned at the intermediate layer of seal wire, and preferably helical spring wrapping wire.Wrapping wire 2
Covering whole nuclear core silk 1, the near-end of nuclear core silk 1 links together with the near-end of wrapping wire 2, and
The far-end of nuclear core silk 1 is in free state, is coated with by wrapping wire 2 but is not attached to together.Excellent
Selection of land, the near-end of nuclear core silk 1 is welded to connect with the near-end of wrapping wire 2, naturally it is also possible to use
Other material connected mode such as such as bond, be clasped.
Sheath 3 is positioned at the outer layer of seal wire and covers the major part of wrapping wire 2 equably.According to
Embodiment shown in Fig. 1, in addition to the subregion in the middle part of seal wire, other region is by sheath 3
Uniform fold, say, that the part not covered by sheath of wrapping wire 2 is positioned in the middle part of seal wire
Subregion, the camber of guidewire distal region can be manipulated by this part wrapping wire of push-and-pull.
According to the embodiment shown in Fig. 4, in addition to the proximal end region of seal wire, other region is by sheath 3
Uniform fold, say, that the part not covered by sheath of wrapping wire 2 is positioned at the near of seal wire
End regions, can manipulate the camber of guidewire distal region by this part wrapping wire of push-and-pull.Ability
Field technique personnel it is also understood that the exposed part of wrapping wire 2 can be according to the different behaviour of doctor
Select as custom, and be not limited to above two embodiment.Sheath 3 is preferably polymerization
Thing sheath, naturally it is also possible to use the material that other is suitable.
According to the structure of above-mentioned seal wire, compared with tradition superslide seal wire, the seal wire of the present invention
Wrapping wire covers whole seal wire, and polymer jacket is not completely covered.Wrapping wire covers whole
Seal wire is in order to improve handling, supportive and the moment of torsion transmission performance of seal wire, and can carry
Make feel more preferably for good sense of touch feedback.Polymer jacket is not completely covered, the most just
Being to say, part wrapping wire is exposed outside, and this allows to pull this part wrapping wire by push-and-pull
Manipulate the camber in wire distal plastotype region.Fig. 2 and Fig. 3 clearly demonstrates and passes through
Push-and-pull pull exposed wrapping wire part to adjust the degree of crook in wire distal plastotype region, side
Just seal wire repeatedly enters conduit, solves elbow superslide wire distal the most well and is difficult to
It is straightened, the problem increasing operation fussy degree.
Next proceeding to reference to Fig. 1, in addition to above mentioned three parts, seal wire is all right
Including safe core filaments 5, it is completely covered by wrapping wire 2 between nuclear core silk 1 and wrapping wire 2.
According to the embodiment shown in Fig. 1, safe core filaments 5 for flat and is positioned at nuclear core silk 1
Side, the two ends of safe core filaments 5 respectively with being proximally and distally connected of wrapping wire 2, be preferably
Weld together, naturally it is also possible to use other material connected modes such as bonding, be clasped.
Additionally, it may occur to persons skilled in the art that, safe core filaments 5 is around nuclear core silk 1 ringwise
Ground is between nuclear core silk 1 and wrapping wire 2.Safe core filaments 5 can provide duplicate protection, keeps away
Exempt from wrapping wire 2 to rupture and leave in the blood vessel, moreover it is possible to conduction axial tensile force, adjust conductive filament head
The camber in end plastotype region.Safe core filaments 5 is preferably stainless steel silk, naturally it is also possible to use
Other suitable material.
Seal wire can also include the coating 4 being coated on the surface of sheath 3.Coating 4 can be special
Fluorine dragon, PVP, polyethylene, polypropylene, polrvinyl chloride, polyester, polyamide, polyimides,
Polyurethanes, polystyrene, Merlon, silicones, fluor resin coating or include
The composite coating of described any combination thereof.
Seal wire according to the present invention mentioned above can enter conduit in use repeatedly, connects down
Will be described.First, the far-end making seal wire enters in conduit and pushes seal wire；
Then, when needed, by pulling the part not covered by sheath of wrapping wire so that seal wire
Remote area bends, to pass through bending channel；When operation completes, extract seal wire out；
Then, by promoting the part not covered by sheath of wrapping wire so that guidewire distal region becomes
Directly, thus beneficially the far-end of seal wire is again introduced in conduit.
It will be apparent to those skilled in the art that, disclosed embodiment can be made various repairing
Change with modification without deviating from the scope of the present invention.Based on this specification with to disclosed herein interior
The practice held, those skilled in the art it will also be appreciated that other embodiment.This specification and
Example should be counted as being merely exemplary, and the true scope of the present invention is wanted by appended right
Ask and equivalent indicates.
Claims (14)
1. an elbow seal wire, including:
Nuclear core silk, described nuclear core silk is positioned at the internal layer of described seal wire；
Wrapping wire, described wrapping wire is positioned at the intermediate layer of described seal wire and covers whole nuclear core silk,
Wherein, the described near-end of nuclear core silk is connected with the near-end of wrapping wire, the far-end of described nuclear core silk
In free state；And
Sheath, described sheath is positioned at the outer layer of described seal wire and covers the big portion of described wrapping wire
Point, the partial denudation not covered by described sheath of described wrapping wire is outside, naked by push-and-pull
The described part being exposed can manipulate the camber of the remote area of described seal wire.
Elbow seal wire the most according to claim 1, also includes safe core filaments, described peace
Core filaments is between described nuclear core silk and wrapping wire entirely, proximally and distally dividing of described safe core filaments
Not with being proximally and distally connected of described wrapping wire.
Elbow seal wire the most according to claim 1 and 2, also includes coating, described painting
Layer is applied on the surface of described sheath.
Elbow seal wire the most according to claim 1, wherein, the far-end of described nuclear core silk
It is tapered.
Elbow seal wire the most according to claim 1, wherein, described wrapping wire is spiral bullet
Spring wrapping wire.
Elbow seal wire the most according to claim 1, wherein, not protected of described wrapping wire
The part that set covers is positioned at the subregion in the middle part of seal wire.
Elbow seal wire the most according to claim 1, wherein, not protected of described wrapping wire
The part that set covers is positioned at the proximal end region of seal wire.
Elbow seal wire the most according to claim 2, wherein, described safe core filaments is flat
Flat-shaped and be positioned at the side of nuclear core silk.
Elbow seal wire the most according to claim 1, wherein, described nuclear core silk uses nickel
Titanium alloy, rustless steel, Ti-Nb alloy, Ti-Ni-X alloy, Cu-Zn alloy, Cu-Zn-Ni
Alloy, Fe-Ni alloy/C or Fe-Mn alloy manufacture.
Elbow seal wire the most according to claim 2, wherein, described safe core filaments is not
Rust steel wire.
11. elbow seal wires according to claim 1, wherein, described sheath is polymer
Sheath.
12. elbow seal wires according to claim 3, wherein, described coating be Teflon,
PVP, polyethylene, polypropylene, polrvinyl chloride, polyester, polyamide, polyimides, poly-ammonia
Carbamate, polystyrene, Merlon, silicones, fluor resin coating or include Teflon
Dragon, PVP, polyethylene, polypropylene, polrvinyl chloride, polyester, polyamide, polyimides,
Polyurethanes, polystyrene, Merlon, silicones, the combination in any of fluororesin
Composite coating.
13. elbow seal wires according to claim 1, wherein, the near-end of described nuclear core silk
Weld together with the near-end of wrapping wire.
14. elbow seal wires according to claim 2, wherein, described safe core filaments near
End and far-end respectively with proximally and distally the welding together of described wrapping wire.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210570427.6A CN103861195B (en) | 2012-12-14 | 2012-12-14 | Trans-radial gets involved superslide seal wire |
| PCT/CN2013/087684 WO2014090077A1 (en) | 2012-12-14 | 2013-11-22 | Transradial intervention super-smooth guidewire |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210570427.6A CN103861195B (en) | 2012-12-14 | 2012-12-14 | Trans-radial gets involved superslide seal wire |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103861195A CN103861195A (en) | 2014-06-18 |
| CN103861195B true CN103861195B (en) | 2016-10-26 |
Family
ID=50900571
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210570427.6A Active CN103861195B (en) | 2012-12-14 | 2012-12-14 | Trans-radial gets involved superslide seal wire |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN103861195B (en) |
| WO (1) | WO2014090077A1 (en) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104436409A (en) * | 2014-11-28 | 2015-03-25 | 中山市普利斯微创介入医械有限公司 | Anti-folding pigtail catheter |
| CN104399175A (en) * | 2014-11-28 | 2015-03-11 | 中山市普利斯微创介入医械有限公司 | Anti-folding guide wire |
| CN104383632A (en) * | 2014-11-28 | 2015-03-04 | 中山市普利斯微创介入医械有限公司 | Anti-folding central venous catheter |
| US10639496B2 (en) | 2016-12-28 | 2020-05-05 | Hua Shang | Blood vessel optical fiber guide wire |
| CN106512232A (en) * | 2016-12-28 | 2017-03-22 | 尚华 | Vascular optical fiber guide wire |
| KR20190103437A (en) * | 2017-03-10 | 2019-09-04 | 아사히 인텍크 가부시키가이샤 | Catheter |
| KR102372611B1 (en) * | 2017-03-22 | 2022-03-10 | 후아 상 | How to use shape memory alloy hypotube and vascular fiber guidewire |
| WO2018170776A1 (en) | 2017-03-22 | 2018-09-27 | 尚华 | Magnetic optical fiber coupling apparatus |
| CN106955423B (en) * | 2017-03-22 | 2020-02-04 | 尚华 | Blood vessel optical fiber catheter |
| WO2018170789A1 (en) * | 2017-03-22 | 2018-09-27 | 尚华 | Blood vessel optical fiber catheter |
| CN106963992B (en) * | 2017-03-22 | 2019-02-22 | 尚华 | A kind of marmem hypotube and its application in blood vessel optical fiber seal wire |
| CN107456647A (en) * | 2017-08-03 | 2017-12-12 | 湖南埃普特医疗器械有限公司 | A kind of seal wire and preparation method thereof |
| CN107362437A (en) * | 2017-08-03 | 2017-11-21 | 湖南埃普特医疗器械有限公司 | A kind of predilation seal wire and preparation method thereof |
| CN110013596B (en) * | 2019-04-24 | 2020-02-11 | 广州启骏生物科技有限公司 | Guide wire for percutaneous puncture of catheter |
| CN113084341A (en) * | 2019-12-19 | 2021-07-09 | 先健科技(深圳)有限公司 | Guide wire, welding device and welding method |
| CN114618070A (en) * | 2022-01-27 | 2022-06-14 | 聚辉医疗科技(深圳)有限公司 | Micro-guide wire |
| CN114711955B (en) * | 2022-05-11 | 2022-11-01 | 上海安通医疗科技有限公司 | Electric control ablation catheter for radial artery |
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|---|---|---|---|---|
| US4798598A (en) * | 1986-05-23 | 1989-01-17 | Sarcem S.A. | Guide for a catheter |
| US4932419A (en) * | 1988-03-21 | 1990-06-12 | Boston Scientific Corporation | Multi-filar, cross-wound coil for medical devices |
| US5084022A (en) * | 1989-10-04 | 1992-01-28 | Lake Region Manufacturing Company, Inc. | Graduated guidewire |
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|---|---|---|---|---|
| US8241230B2 (en) * | 2007-09-25 | 2012-08-14 | Cook Medical Technologies Llc | Variable stiffness wire guide |
| US8864685B2 (en) * | 2010-10-22 | 2014-10-21 | Cook Medical Technologies Llc | Wire guide having two safety wires |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4798598A (en) * | 1986-05-23 | 1989-01-17 | Sarcem S.A. | Guide for a catheter |
| US4932419A (en) * | 1988-03-21 | 1990-06-12 | Boston Scientific Corporation | Multi-filar, cross-wound coil for medical devices |
| US5084022A (en) * | 1989-10-04 | 1992-01-28 | Lake Region Manufacturing Company, Inc. | Graduated guidewire |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103861195A (en) | 2014-06-18 |
| WO2014090077A1 (en) | 2014-06-19 |
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Effective date of registration: 20190117 Address after: Room 201, 2nd floor, Building 5, 1303 Asia Pacific Road, Nanhu District, Jiaxing City, Zhejiang Province Patentee after: Minimally invasive Longmai Medical Technology (Jiaxing) Co., Ltd. Address before: 201 203 No. 501 Newton Road, Zhangjiang High-tech Park, Pudong, Shanghai Patentee before: Shanghai MicroPort Medical Equipment (Group) Co., Ltd. |
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Effective date of registration: 20191223 Address after: 201203 Room 102, building 2, No. 501, Newton Road, China (Shanghai) pilot Free Trade Zone, Pudong New Area, Shanghai Patentee after: Shanghai dragon minimally invasive medical equipment Co. Ltd. Address before: Room 201, 2nd floor, Building 5, 1303 Asia Pacific Road, Nanhu District, Jiaxing City, Zhejiang Province Patentee before: Minimally invasive Longmai Medical Technology (Jiaxing) Co., Ltd. |