CN103816006B - The equipment that a kind of non-implantable excites blind visual to experience through body surface - Google Patents
The equipment that a kind of non-implantable excites blind visual to experience through body surface Download PDFInfo
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- CN103816006B CN103816006B CN201410058933.6A CN201410058933A CN103816006B CN 103816006 B CN103816006 B CN 103816006B CN 201410058933 A CN201410058933 A CN 201410058933A CN 103816006 B CN103816006 B CN 103816006B
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Abstract
The invention discloses the equipment that a kind of non-implantable excites blind visual to experience through body surface, this equipment comprises: main control module; Input module, it is connected to main control module, and for receiving the signalization relevant with the frequency of electric current and/or amplitude of user's input; At least one stimulating current generation module, it is connected to main control module, and under the control of main control module, producing at least one group of stimulating current according to signalization, stimulating current is low frequency pulse current and the superposing of low frequency pulse current or low frequency pulse current and medium-frequency pulse electric current; Output module, it is connected at least one stimulating current generation module, and output module comprises the non-implantable electrode of many groups, and electrode contacts with body surface, and stimulating current exports from described electrode and excites blind person to produce photoreception through body surface.Implement technical scheme of the present invention, safe and reliable, cost is lower.
Description
Technical field
The present invention relates to biomedical engineering technology field, particularly relate to the equipment that a kind of non-implantable excites blind visual to experience through body surface.
Background technology
The mankind are externally provided by vision in the information of the understanding in the world about 90%, normally complete vision produces like this: the optical system of eyes by the image objects in the external world on the retina, picture signal is converted to bioelectrical signals by the photoreceptor cell，photosensory cell on retina, then carry out being transmitted to brain visual cortex by optic nerve fiber after preliminary treatment through cell membrane neutral net, brain visual cortex again processes the bioelectrical signals obtained and perception produces vision.Any one link of pathways for vision sustains damage or pathological changes all can cause blind, such as: retinitis pigmentosa, and maculopathy, the blindness problems that moderate and severe degree of amblyopia and other diseases blinding or wound are brought.According to the international low visual acuity of WHO1973 and blindness grade scale (preferably correcting defects of vision): 3 grades of blindness <0.05 ~ 0.02, or radius of view <10 degree; 4 grades of blindness <0.02 ~ light sensations, or radius of view <5 degree; 5 grades of blindness no light perceptions.
In numerous cures, the scheme utilizing implanted chip and the remaining visual cell of electrode pair retina to implement electricity irritation can make the vision of patient obtain recovery to a certain extent.Different according to implant electrode position, can be divided on stimulating visual cortex, optic nerve, retina and the lower 4 kinds of schemes of retina.Its principle is the artificial analog vision signal of telecommunication, and the visual system connecting human body meticulous carries out stimulus of direct current conduction, makes visual cortex produce the excitement of similar light stimulation based retinal initiation, to excite effective phosphene.Such as, application number be 200610025215.4 Chinese invention patent application disclose a kind of implantable sheet type optic nerve micro stimulating electrode, it stimulates optic nerve fiber, the stimulating current that stimulator produces is transmitted to visual cortex by optic nerve fiber, the excitement produced after making visual cortex produce similar light stimulation based retinal, thus generation phosphene, and the current potential of optic nerve fiber can be recorded.Application number be 200910197192.9 Chinese invention patent application disclose a kind of the phosphene generating apparatus and the method thereof that emulate prosthetic vision, it can obtain the simulation result close to practical situation, and can meet multiparameter experiment needs.Be entitled as the Master's thesis that the microelectrode for retina reparation studies and devise a kind of long-term active flexible retina of implanted and optic nerve stimulation electrode, and make the stable in properties of electrode, there is good biocompatibility, can long-term work and not easily by corrosion in body fluid.But the solution of above-mentioned implanted is from effect, artificial vision can only provide and be confined to visual experience useful for individuality in certain limit, do not comprise the full details of regeneration vision, as color, the degree of depth, quality structure etc., it can not be ignored the damage of visual system, and operation also has potentiality risk, except impact is attractive in appearance, also there is mental pressure large, the problems such as costly.
Summary of the invention
The technical problem to be solved in the present invention is, the above-mentioned implantable electrode for prior art exists risk, costly defect, provides a kind of risk low and the low non-implantable of the expense equipment that excites blind visual to experience through body surface.
The technical solution adopted for the present invention to solve the technical problems is: construct the equipment that a kind of non-implantable excites blind visual to experience through body surface, comprising:
Main control module;
Input module, it is connected to described main control module, and for receiving the signalization relevant with the frequency of electric current and/or amplitude of user's input;
At least one stimulating current generation module, it is connected to described main control module, and under the control of described main control module, produce at least one group of stimulating current according to described signalization, described stimulating current is low frequency pulse current and the superposing of low frequency pulse current or low frequency pulse current and medium-frequency pulse electric current;
Output module, it is connected at least one stimulating current generation module described, and described output module comprises the non-implantable electrode of many groups, and described electrode contacts with body surface, and described stimulating current exports from described electrode and excites blind person to produce photoreception through body surface.
In the equipment exciting blind visual to experience through body surface in non-implantable of the present invention, described stimulating current is that frequency is in the low frequency pulse current of below 60Hz and superposing of other low frequency pulse current; Or,
Described stimulating current is that frequency is in the low frequency pulse current of below 60Hz and superposing of medium-frequency pulse electric current.
In the equipment exciting blind visual to experience through body surface in non-implantable of the present invention, one group of non-implantable electrode comprises two electrodes contacted with the body surface of circumference of eyes respectively.
In the equipment exciting blind visual to experience through body surface in non-implantable of the present invention, one group of non-implantable electrode comprises an electrode contacted with eyelid and an electrode contacted with hindbrain body surface.
In the equipment exciting blind visual to experience through body surface in non-implantable of the present invention, described electrode is Corneal electrode, to excite blind person to produce photoreception by cornea.
In the equipment exciting blind visual to experience through body surface in non-implantable of the present invention, in the non-implantable electrode of described many groups, the non-implantable electrode of each group exports the stimulating current of different frequency and/or different amplitude.
In the equipment exciting blind visual to experience through body surface in non-implantable of the present invention, one group of non-implantable electrode gap certain hour ground exports the stimulating current of different frequency and/or different amplitude.
In the equipment exciting blind visual to experience through body surface in non-implantable of the present invention, described equipment also comprises many group color lamp groups, often organizes color lamp group and produces a kind of monochromatic light and excite for carrying out a kind of monochromatic light vision to blind person.
In the equipment exciting blind visual to experience through body surface in non-implantable of the present invention, described equipment also comprises intense light source, and described intense light source produces high light and excites for carrying out daylight vision to blind person.
In the equipment exciting blind visual to experience through body surface in non-implantable of the present invention, described equipment also comprises display module, it is connected to described main control module, and for showing the configuration information relevant with the frequency of electric current and/or amplitude and stimulating current information.
Implement technical scheme of the present invention, the present invention passes through the stimulating current through superposition of the different amplitude of micro-control technology export and/or different frequency, and act on body surface by electrode, photoreception is produced to make blind person, the visual experience of such as colourama and image, and, the electrode of this non-implantable, safe noninvasive mode can realize blind person and recover lost eyesight, and can promote more in a short time recover lost eyesight after vision, reach basic living and take care of oneself or the vision level of orthobiosis, therefore, safe and reliable, and cost is lower.
Accompanying drawing explanation
Below in conjunction with drawings and Examples, the invention will be further described, in accompanying drawing:
Fig. 1 is the logic chart of the apparatus embodiments one that the non-implantable of the present invention excites blind visual to experience through body surface;
Fig. 2 is the schematic diagram of input module embodiment one in Fig. 1;
Fig. 3 is the circuit diagram of main control module embodiment one in Fig. 1;
Fig. 4 is the circuit diagram of a frequency generating subunit of Fig. 1 medium frequency generation unit;
Fig. 5 is the partial circuit figure of amplitude generation unit embodiment one in Fig. 1;
Fig. 6 is the partial circuit figure of amplitude generation unit embodiment one in Fig. 1;
The circuit diagram of power amplification unit and overcurrent protection module embodiment one in Fig. 7 equipment that to be the non-implantable of the present invention excite blind visual to experience through body surface;
Fig. 8 is that the non-implantable of the present invention is prized through the equipment that body surface excites blind visual to experience the circuit diagram of lamp control module and driver module embodiment one.
Detailed description of the invention
The operational approach of the relevant elements of objects, features and characteristic of the present invention and structure and function and being combined in when reading following description and above claim with reference to accompanying drawing of parts will become more obvious.Accompanying drawing to be understood clearly be only used to the purpose of illustration and description and be not intended to as restriction of the present invention.
Fig. 1 is the logic chart of the apparatus embodiments one that the non-implantable of the present invention excites blind visual to experience through body surface, this equipment comprises main control module 11, input module 12, stimulating current generation module 1, output module 16 and display module 17, wherein, stimulating current generation module 1 comprises frequency generating units 13, amplitude generation unit 14, power amplification unit 15.In addition, input module 12, frequency generating units 13, amplitude generation unit 14 are connected with main control module 11 respectively with display module 17, and connection alleged here can be electrical connection and/or mechanical connection.Further, power amplification unit 15 is connected with amplitude generation unit 14 and output module 16 respectively.It should be noted that at this, a stimulating current generation module 1 and this frequency generating units 13 corresponding to stimulating current generation module 1 is illustrate only in figure, an amplitude generation unit 14 and a power amplification unit 15, should understand, when the quantity of stimulating current generation module 1 is multiple, namely when producing many group stimulating currents, the quantity of frequency generating units is also correspondingly multiple, that is when producing the many groups the be formed by stacking stimulating current respectively by low frequency pulse current and low frequency pulse current or low frequency pulse current and medium-frequency pulse electric current, the quantity also corresponding increase of amplitude generation unit and power amplification unit.In the present invention, low frequency pulse current refers to the pulse current of medically alleged frequency lower than 1000Hz, medium-frequency pulse electric current refers to the medically alleged pulse current of frequency between 1KHz ~ 100KHz, and low frequency pulse current and medium-frequency pulse electric current are all the small area analysis that can not work the mischief to human body.In this embodiment, input module 12 is for receiving the signalization of user's input, and this signalization can be the signalization relevant with the frequency of electric current and/or amplitude; Display module 17 is for showing the configuration information relevant with the frequency of electric current and/or amplitude and stimulating current information; Frequency generating units 13, under the control of main control module 11, produces the pulse signal of one group of medium and low frequency according to signalization; Amplitude generation unit 14 is under the control of main control module 11, the pulse signal exported according to signalization and corresponding frequencies generation unit produces the stimulating current signal of corresponding amplitude, and power amplification unit 15 is for carrying out power amplification to this stimulating current signal; Output module 16 comprises the non-implantable electrode of many groups, and this electrode exports stimulating current signal and excites blind person to produce photoreception through body surface.In the various embodiments of the application, (namely body surface not only comprises health body surface, skin) also comprise the cornea of eyeball, that is, can according to be with health body surface or and Corneal Contact, and select various applicable electrode, and what this photoreception was concrete can be colourama and image vision impression, wherein, single group electrode has 2 tunnels to export, its by plug, wire and electrode tip three part form.Preferably, plug separately having one can electric conductivity circular opening, makes another group electrode plug can insert this circular hole and realizes expansion.Electrode tip quantity can be 2,4,6 etc., makes the electrode of this equipment in use have good motility and extensibility.In addition, for the benefit of hand-held, partial electrode head is circle strip structure.In an exemplary embodiment, electrode tip is contacted with the body surface of circumference of eyes, thus realize exciting the photoreception of vision the best.Certainly, electrode tip can be contacted with the optional position of body surface, and all can realize exciting the photoreception of vision, the difference of the electrode tip contact of different sites is the different stimulation effect of acquisition and experience.Further more optimizedly, corresponding use two electrode tips, one of them electrode tip contacts with eyelid and another electrode tip contacts with hindbrain body surface, carries out photoreception thus excite between two electrode tips perpendicular to eyeball.Again further preferably, electrode is Corneal electrode, and namely this electrode directly contacts with cornea, thus more directly can be excited the photoreception of blind person by cornea.At this, the active electrode directly contacted with cornea can be the electrode be applicable to of various types of corneal contact lens electrodes and other kinds.
In addition, it should be noted that, the stimulating current signal that this power amplification unit exports is superposed by pulse signal and produces.In the non-implantable electrode of described many groups, the non-implantable electrode of each group exports the stimulating current of different frequency and/or different amplitude.Can be low frequency pulse current and low frequency pulse current or low frequency pulse current are carried out superposing with medium-frequency pulse electric current thus obtains stimulating current signal particularly, that is one of feature of the present invention is it is not produce single low frequency pulse current signal or single medium-frequency pulse current signal as stimulating current signal but using the pulsed current signal of superposition as stimulating current signal, concrete additive process is not described in detail at this in addition, it can adopt method suitable in prior art, and, this equipment is as medical apparatus and instruments, output voltage meets medical electrical equipment code requirement, as preferred embodiment, output voltage is at below 36V.In an exemplary embodiment, stimulating current signal be frequency in the low frequency pulse current of below 60Hz and superposing of other low frequency pulse current, understandable, this other low frequency pulse current can be another or multiple low frequency pulse current.In another one exemplary embodiment, stimulating current be frequency in the low frequency pulse current of below 60Hz and superposing of medium-frequency pulse electric current, equally, this other medium-frequency pulse electric current can be another or multiple medium-frequency pulse electric current.The quantity of the pulse current of superposition and choice for use low frequency or medium-frequency pulse electric current is needed to carry out superposing and can the requirement needed for the individual specificity of the object that is stimulated and stimulation change flexibly.In addition, by selecting the pulse current of this characteristic frequency section (below 60Hz) to carry out superposing thus realize carrying out optimum photoreception to blind person to excite.In addition, in an exemplary embodiment, by carrying out dynamic change to frequency and regulating accordingly amplitude according to the difference of the physiology resistance of particular individual, thus realization excites the diversification of specific blind person and personalization, that is achieves optimum photoreception to specific blind person and excites.
In addition, user arranges by input module and exports stimulating current discontinuously, and like this, one group of non-implantable electrode just can export the stimulating current of different frequency and/or different amplitude separated in time.
Preferably, the equipment that this non-implantable excites blind visual to experience through body surface also can comprise overcurrent protection module, and this overcurrent protection module carries out overcurrent protection to the stimulating current signal that power amplification unit exports.
The following describes the concrete structure of the equipment preferred embodiment that this non-implantable excites blind visual to experience through body surface:
Composition graphs 2, input module selects the keyboard of 4*4, and the function of each button is as follows:
" 1 ": increase photoelectric functional intensity " 2 ": weaken photoelectric functional intensity
" 3 ": increase frequency " A ": reduce frequency
" 4 ": intermediate frequency adds " 5 ": 3 prescription cases add
" 6 ": 3 prescription cases subtract " 7 ": second channel intensity adds
" 8 ": subtract intensity " 9 ": 3 prescription cases are decided to be 3 seconds once
" B ": regularly " C ": 3 schemes 5 seconds once
" D ": pause function conversion gear " * ": intelligent function is automatic
Composition graphs 3, main control module is as the core devices of whole circuit, all information all passes through this device process, such as, atmel corp's model can be adopted to be the single-chip microcomputer U1 of AT89S52, this single-chip microcomputer U1 is a kind of low-power consumption, high-performance CMOS 8 8-digit microcontroller, has 8K in-system programmable components flash storage.Use the manufacture of Atmel company high-density nonvolatile memory technology, with the instruction of industrial 80C51 product and pin completely compatible.On sheet, Flash allows program storage in-system programmable components, is also suitable for conventional programming device.On a single chip, have 8 dexterous bit CPUs and in-system programmable components Flash, height is flexible, the solution of super efficient for numerous embedded Control application system provides to make AT89S52.Its main performance is as follows: compatible with MCS-51 single-chip microcomputer product; 8K byte in-system programmable components flash storage; 1000 erase-write cycles; Full static state operation: 0Hz ~ 33Hz; Three grades of encipheror memorizeies; 32 programmable I/O mouth lines; Three 16 bit timing device/enumerators; Eight interrupt sources; Full duplex UART serial-port; Low power idle and power-down mode; Interrupt after power down waking up; WatchDog Timer; Double Data pointer; Power down identifier.And in this single-chip microcomputer U1, P1.0-P1.7 is external connection keyboard interface, respectively can the function such as frequency and output amplitude that produces of control system; INT0 (P32), INT1 (P33), TXD (P31) and RXD(P30) be four pulse output ends, it is by by Keyboard Control, can make single-chip microcomputer U1 export needed for intermediate frequency first-harmonic shape and the waveform of frequency of modulated wave; 31 feet connect high level and represent use internal program memory; The external 12MHZ crystal oscillator of 18 and 19 pin, for the single-chip microcomputer U1 work generation cycle is the clock of 1US, two electric capacity C2 and C3 play fine setting effect to crystal oscillator frequency.In addition, doctor can store multiple specific series of programs scheme according in patient's patient's condition selection machine.
Display module selects Dot-matrix Graphic LCD, such as, adopts model to be that TG12864 display (not shown) is to show relevant information.Composition graphs 1, J1 is resistor chain, and resistance is 10 kilo-ohms, and it provides pull-up resistor for single-chip microcomputer P00-P07 mouth.Model is the display of TG12864 is that one has 4/8 parallel-by-bits, 2 lines or 3 line serial multiple interfaces modes, the inner Dot-matrix Graphic LCD containing GB one-level, secondary simplified form of Chinese Character character library, its display resolution is 128 × 64, built-in 8192 16*16 point Chinese characters and 128 16*8 point ascii character-sets.Utilize this display interface mode and operational order simply and easily flexibly, complete Chinese man-machine interaction graphical interfaces can be formed.The Chinese character of 8 × 4 row 16 × 16 dot matrix can be shown, also can complete figure display.In addition, Low-voltage Low-power is its another distinguishing feature.Its fundamental characteristics is as follows: low supply voltage (VDD:+3.0--+5.5V); Display resolution: 128 × 64 points; Built-in Hanzi font library, provides 8192 16 × 16 dot matrix Chinese characters (simplified and traditional body is optional); Built-in 128 16 × 8 dot characters; 2MHZ clock frequency; Display mode: STN, semi-transparent, just aobvious; Type of drive: 1/32DUTY, 1/5BIAS; View directions: 6 points; Backlight mode: the highlighted White LED of sidepiece, power consumption is only 1/5-1/10 of common LED; Communication modes: serial, parallel port are optional; Built-in DC-DC change-over circuit, without the need to additional negative pressure; Without the need to chip selection signal, simplify software design; Operating temperature: 0 DEG C-+55 DEG C; Storing temperature :-20 DEG C-+60 DEG C.
Frequency generating units comprises two frequency generating subunit, and each frequency generating subunit can produce intermediate frequency or low frequency signal.The circuit structure of one of them frequency generating subunit is described below in conjunction with Fig. 4, in this frequency generating subunit, the first end of the first resistance R8 connects the pulse output end (PULSEI1) of single-chip microcomputer U1, second end of the first resistance R8 connects the base stage of the first audion BG1, the grounded emitter of the first audion BG1, the colelctor electrode of the first audion BG1 connects 9V voltage by the second resistance R9, the outfan (PULSE1) of the current collection of the first audion BG1 very this frequency generating units.Should be understood that the circuit structure of another frequency generating subunit is identical with it, and its outfan is PULSE2.
Composition graphs 5 and Fig. 6, in amplitude generation unit, D/A converter selects model to be the D/A converter U2 that 4 passage, 8 current potentials of TLC5620 export, analog switch selects model to be the analog switch module of CD4066, this analog switch module comprises 4 independently analog switches, and two analog switches U5A, U5B are only shown in figure.The reference edge (REFA) of D/A converter U2 connects the adjustable end of rheostat W3, and the another two ends of rheostat W3 connect high voltage and ground respectively, for providing reference voltage for D/A converter, thus reach the object of span of control limit of control.The digital quantity serial line interface (DATA) of D/A converter U2, clock interface (CLK) and serial load mode control port (LOAD) meet the corresponding output end (P22 of single-chip microcomputer respectively, P21, P20), the in-phase input end of the output termination amplifier U4A of D/A converter U2, its outfan of anti-phase input termination of amplifier U4A, the outfan of amplifier U4A also connects the input of the first analog switch U5A, the outfan of the first analog switch U5A connects the input of the second analog switch U5B, the control end of the first analog switch U5A and the control end of the second analog switch U5B meet the outfan (PULSE1 of two frequency generating units respectively, PULSE2), the outfan of the second analog switch U5B is the outfan (OUT1) of this amplitude generation unit.In addition, between the outfan that resistance R3 is connected to the first analog switch U5A and ground, resistance R4 is between the outfan and ground of the second analog switch U5B, and in other embodiments, resistance R3, R4 can save.
Composition graphs 7, in power amplification unit, the inverting input of the second amplifier U4C is by the 4th resistance R10 ground connection, the in-phase input end of the second amplifier U4C connects the outfan (OUT1) of the second analog switch U5B by the 5th resistance R17, the outfan of the second amplifier U4C connects its inverting input by the 3rd resistance R18, the base stage of the second audion BG5 connects the outfan of the second amplifier U4C, the colelctor electrode of the second audion BG5 connects 9V voltage, the outfan of the transmitting of the second audion BG5 very this power amplification unit, connects multi-group electrode by interface J31.In addition, in overcurrent protection module, the negative pole of the first diode D1 connects the colelctor electrode pole of the second audion BG5, and the positive pole of the first diode D1 and the negative pole of the second diode D2 connect the emitter stage of the first audion BG5 in the lump, the plus earth of the second diode D2.
In addition, the equipment that non-implantable of the present invention excites blind visual to experience through body surface also comprises: many group color lamp groups, color light control module and driver module, and wherein, color light control module is for receiving the mode setting signal of color lamp group; Driver module is used for controlling described color lamp group according to mode setting signal and carries out luminescence, one group of color lamp group produces a kind of monochromatic light and excites for carrying out a kind of monochromatic light vision to blind person, that is, make further vision to blind person to excite, this monochromatic light such as can be HONGGUANG, gold-tinted, blue light etc. and can change flexibly according to actual needs.Understandable, this monochromatic light can be obtained by red green blue tricolor mixing preparation.
Suppose that color lamp group shares four groups, composition graphs 8, in driver module, shift register selects model to be the shift register U3 of MC14015, clock circuit is made up of 555 intervalometer U4 and periphery components and parts, for shift register U3 provides clock signal, and rheostat W1 is for controlling the interval of color lamp light on and off.Four driving audion Q1, Q2, Q3, the base stage of Q4 is respectively by current-limiting resistance R22, R23, R24, R25 connects four outfan (Q1A of shift register U3, Q2A, Q3A, Q4A), four driving audion Q1, Q2, Q3, the grounded emitter of Q4, four driving audion Q1, Q2, Q3, Q4 colelctor electrode respectively by current-limiting resistance R26, R27, R28, R29 connects bidirectional triode thyristor Q6, Q7, Q8, the control pole of Q9, bidirectional triode thyristor Q6, Q7, Q8, the two ends of Q9 connect positive pole and the negative pole of corresponding color lamp group (not shown) respectively by interface J2.
Composition graphs 8, color light control module comprises band switch and for making the selection circuit of corresponding bidirectional triode thyristor conducting according to the setting of band switch, wherein, band switch connects selection circuit by interface J3, selection circuit comprises diode D3-D8, audion Q5 and resistance R11, wherein, diode D3, D4, D5, the positive pole of D6 connects four outfans of shift register U3 respectively, the negative pole of diode D3 and the positive pole of diode D7 connect the first contact of band switch in the lump by interface J3, the negative pole of diode D4 and the positive pole of diode D9 connect the second contact of band switch in the lump by interface J3, the negative pole of diode D5 and the positive pole of diode D8 connect the 3rd contact of band switch in the lump by interface J3, the negative pole of diode D6 connects the 4th contact of band switch by interface J3, diode D7, D9, the negative pole of D8 connects the 5th contact of band switch in the lump by interface J3, the base stage of audion Q5 connects the 6th contact of band switch by resistance R20 and interface J3, the grounded emitter of audion Q5, the colelctor electrode of audion Q5 connects high voltage by resistance R21, the colelctor electrode of audion Q5 also connects the data input pin of shift register U3.
In an exemplary embodiment, the equipment that non-implantable of the present invention excites blind visual to experience through body surface also comprises intense light source, and intense light source produces high light and excites for carrying out high light to blind person, that is, makes further vision excite blind person.In the various embodiments of the application, intense light source refers to that colour temperature is at more than 6000K, and brightness can up to 32000LM(lumen) light source (such as, white light source), and this intense light source can be such as xenon lamp or Halogen light, preferably uses xenon lamp in addition.
Explanation is needed at this, when use intense light source to blind person carry out high light excite time, from adopt passage of scintillation light different with pictorial stimulus in prior art, the embodiment of the application will use high color temperature and high brightness and lasting stimulation mode but not flashing mode, thus can obtain more excellent vision and excite.
In an exemplary embodiment, the operation principle of the equipment that this non-implantable excites blind visual to experience through body surface is described: first user arranges frequency and amplitude by the button of input module, this configuration information is after being sent to single-chip microcomputer U1, single-chip microcomputer U1 exports corresponding pulse signal, corresponding frequency generating units according to this output of pulse signal intermediate frequency or low frequency signal, and sends into the control end of the first analog switch U5A, the second analog switch U5B.Simultaneously, single-chip microcomputer U1 controls the analogue signal that D/A converter U2 exports corresponding amplitude, this analogue signal is after first analog switch U5A, U5B, become the stimulating current signal with certain frequency and certain amplitude, this stimulating current signal, after amplifier U4C and audion BG5 amplifies, exports electrode to by interface J31.When electrode is positioned over body surface (not only at eye and head, and in health plurality of positions such as hands, foot, breast, the back of the body, abdomen, necks), stimulating current conducts to visual system, to activate not yet thoroughly downright bad visual cell, recovers and regeneration visual performance.Therefore, this mode by electrode contact body surface, can produce the visual experience of colourama and image, and test proves, part 5 grades of blind persons still can activate remaining visual cell in this way.By stimulating, blind person can feel by such as finding doorway from unglazed, the visual space tests such as positioning object and 1-3 rice identification index; Through repeatedly stimulating further to train, vision all obtains effective rising, and the best can be promoted to more than 0.5 vision, and this vision comprises the full details of regeneration vision, and as color, the degree of depth, quality structure, has stereopsis and the meticulous ability of looking.For there being vision crowd monitoring, electrode selects the plurality of positions comprising body limbs and metastomium beyond eye, adopt binocular closure state, the sites placed with electrode of visual information is different with parameter to change, color adularescent, blueness, yellow, redness, green and secondary colour, form somewhat shape, column, the multiple figure such as netted, the brightness of visual experience is enough, also can perception under eyes-open state.
In addition, user selects different color lamp group work by band switch, be specially: the work and the cut-off that are controlled audion Q5 by the various combination of its first to five contact, the data input pin of shift register U3 received by the colelctor electrode of audion Q5, thus make the outfan of shift register U3 export four drive singal, these four drive singal are respectively by the work driving audion to control four bidirectional triode thyristors, diode D3-D9 simultaneously by one-way conduction makes color lamp group according to different frequency luminance work, such as flicker is beated, vision is made and further excites to train vision.
In addition, by intense light source, generation high light is made further vision to blind person and is excited further to train vision.
The foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, for a person skilled in the art, the present invention can have various modifications and variations.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within right of the present invention.
Claims (7)
1. the non-implantable equipment that excites blind visual to experience through body surface, is characterized in that, comprising:
Main control module;
Input module, it is connected to described main control module, and for receiving the signalization relevant with the frequency of electric current and/or amplitude of user's input;
At least one stimulating current generation module, it is connected to described main control module, and under the control of described main control module, produce at least one group of stimulating current according to described signalization, described stimulating current is that frequency is in the low frequency pulse current of below 60Hz and superposing of other low frequency pulse current; Or described stimulating current is that frequency is in the low frequency pulse current of below 60Hz and superposing of medium-frequency pulse electric current;
Output module, it is connected at least one stimulating current generation module described, and described output module comprises the non-implantable electrode of many groups, and described electrode contacts with body surface, and described stimulating current exports from described electrode and excites blind person to produce photoreception through body surface;
For generation of the intense light source that high light excites to carry out daylight vision to blind person, described intense light source is colour temperature is 6000K, and brightness is the xenon lamp of 32000LM;
Many groups color lamp group, often organize color lamp group and produce a kind of monochromatic light and excite for carrying out a kind of monochromatic light vision to blind person, described monochromatic light comprises HONGGUANG, gold-tinted, blue light.
2. the non-implantable according to claim 1 equipment that excites blind visual to experience through body surface, it is characterized in that, one group of non-implantable electrode comprises two electrodes contacted with the body surface of circumference of eyes respectively.
3. the non-implantable according to claim 1 equipment that excites blind visual to experience through body surface, it is characterized in that, one group of non-implantable electrode comprises an electrode contacted with eyelid and an electrode contacted with hindbrain body surface.
4. the non-implantable according to claim 1 equipment that excites blind visual to experience through body surface, it is characterized in that, described electrode is Corneal electrode, to excite blind person to produce photoreception by cornea.
5. the non-implantable according to claim 1 equipment that excites blind visual to experience through body surface, is characterized in that, in the non-implantable electrode of described many groups, the non-implantable electrode of each group exports the stimulating current of different frequency and/or different amplitude.
6. the non-implantable according to claim 1 equipment that excites blind visual to experience through body surface, is characterized in that, one group of non-implantable electrode gap certain hour ground exports the stimulating current of different frequency and/or different amplitude.
7. according to the equipment that the arbitrary described non-implantable of claim 1-6 excites blind visual to experience through body surface, it is characterized in that, described equipment also comprises display module, it is connected to described main control module, and for showing the configuration information relevant with the frequency of electric current and/or amplitude and stimulating current information.
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| CN104352303B (en) * | 2014-10-30 | 2017-11-07 | 北京大学 | The equipment that electro photoluminescence forms artificial vision |
| US11007367B2 (en) * | 2016-03-16 | 2021-05-18 | Nova Oculus Canada Manufacturing Ulc | Microcurrent device for the treatment of visual disease |
| CN106236377A (en) * | 2016-09-12 | 2016-12-21 | 北京大学 | SCNS is utilized to form the equipment of artificial vision |
| CN113398471B (en) * | 2021-07-28 | 2022-08-23 | 浙江京兆医疗器械有限公司 | Method and equipment for assisting in controlling eye diseases |
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