CN103519828A - Analyte detection system and sensing label thereof - Google Patents
Analyte detection system and sensing label thereof Download PDFInfo
- Publication number
- CN103519828A CN103519828A CN201310538299.1A CN201310538299A CN103519828A CN 103519828 A CN103519828 A CN 103519828A CN 201310538299 A CN201310538299 A CN 201310538299A CN 103519828 A CN103519828 A CN 103519828A
- Authority
- CN
- China
- Prior art keywords
- magnetic substance
- analyte
- concentration level
- elastomeric material
- subcutaneous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012491 analyte Substances 0.000 title claims abstract description 81
- 238000001514 detection method Methods 0.000 title claims abstract description 32
- 238000007920 subcutaneous administration Methods 0.000 claims abstract description 30
- 239000000463 material Substances 0.000 claims abstract description 29
- 230000006698 induction Effects 0.000 claims abstract description 17
- 239000000126 substance Substances 0.000 claims description 68
- 239000013536 elastomeric material Substances 0.000 claims description 36
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 34
- 239000008103 glucose Substances 0.000 claims description 34
- 108090000790 Enzymes Proteins 0.000 claims description 17
- 102000004190 Enzymes Human genes 0.000 claims description 17
- 229940088598 enzyme Drugs 0.000 claims description 17
- 108010015776 Glucose oxidase Proteins 0.000 claims description 10
- 239000004366 Glucose oxidase Substances 0.000 claims description 10
- 238000004891 communication Methods 0.000 claims description 10
- 229940116332 glucose oxidase Drugs 0.000 claims description 10
- 235000019420 glucose oxidase Nutrition 0.000 claims description 10
- 230000002378 acidificating effect Effects 0.000 claims description 7
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 claims description 6
- 238000004026 adhesive bonding Methods 0.000 claims description 3
- 239000013013 elastic material Substances 0.000 abstract 4
- 238000000354 decomposition reaction Methods 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 description 29
- 239000008280 blood Substances 0.000 description 29
- 238000010586 diagram Methods 0.000 description 8
- 239000000523 sample Substances 0.000 description 8
- 239000000203 mixture Substances 0.000 description 7
- 238000012544 monitoring process Methods 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- 230000001939 inductive effect Effects 0.000 description 3
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 206010012601 diabetes mellitus Diseases 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000011505 plaster Substances 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 208000013016 Hypoglycemia Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 230000010030 glucose lowering effect Effects 0.000 description 1
- 230000002641 glycemic effect Effects 0.000 description 1
- 201000001421 hyperglycemia Diseases 0.000 description 1
- 230000002218 hypoglycaemic effect Effects 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 238000000034 method Methods 0.000 description 1
Images
Abstract
The invention discloses an analyte detection system and a sensing label of the analyte detection system. The analyte detection system comprises the sensing label (101) and a magnetic detector (102), wherein the sensing label (101) is embedded under the skin and provided with a magnetic elastic material (111) coated by a bio-enzyme (112), the bio-enzyme (112) is used for reacting with the subcutaneous analyte to conduct decomposition so as to obtain a corresponding derived material, the vibration frequency of the magnetic elastic material (111) changes along with the concentration of the derived material, the magnetic detector (102) is used for exerting magnetic induction on the magnetic elastic material (111), detecting the vibration frequency of the magnetic elastic material (111) and determining the concentration level of the corresponding analyte according to the corresponding relation between a prestored vibration frequency value and the analyte concentration level. The analyte detection system can be conveniently worn, and the influence on the movement of a wearer is reduced.
Description
Technical field
The present invention relates to medical field tests, relate in particular to a kind of analyte detection system and sensing label thereof.
Background technology
At present, in medical field tests, very general for the test of analyte.Described analyte is the concentration of glucose in blood, body fluid for example, can adopt the special-purpose tester with sensor to test.The blood sugar concentration of blood glucose meter in can testing human blood for example.
At present also occurred can be used for implanting subcutaneous analyte detection system, for example, had at present a kind of dynamic blood sugar monitoring system, this system is comprised of blood sugar recording device, information extractor, inductive probe, cable and analysis of blood sugar software etc.It is subcutaneous that described inductive probe is embedded in patient, is useful on the sensor of induction blood glucose concentration value on this inductive probe, can detect the blood sugar concentration in blood glucose, generates the signal of telecommunication; Described blood sugar recording device by cable with probe is connected, every 10 second the reception-inferior signal of telecommunication, every 5 minutes storage a meansigma methods, can automatically record 288 blood glucose values every day.Dynamic blood sugar monitoring system is the blood glucose value of record patient automatically, and by computer download complete odd-numbered day blood glucose figure, many days blood glucose figure, have meal before and after blood glucose figure, special time period blood glucose figure and statistics table report, therefrom can understand comprehensive blood glucose information, find many rules of ND hyperglycemia, hypoglycemia and blood glucose fluctuation at ordinary times, for drafting and assess the glucose-lowering treatment scheme of rationalization, individuation, provide valuable clinical foundation, and effectively help diabetics education, improve patient to the understanding of diabetes and compliance.
But, the analyte detection system that existing implantation is subcutaneous, it implants the sensor of all installing on subcutaneous probe accordingly for detection of analyte level, this sensor need to be by electric drive, therefore this probe must be connected with extraneous information recorder by cable, by equipment power supplies such as extraneous information recorders, just can be worked long hours, owing to being embedded in subcutaneous probe and external device, need to be connected with cable as information recorder etc., therefore make wearer's action very inconvenient, the accident that causes probe to come off owing to being not intended to tow cable even can occur.
Summary of the invention
In view of this, main purpose of the present invention is to provide a kind of analyte detection system and sensing label thereof, to facilitate, wears, and reduces the impact on wearer's action.
In order to realize foregoing invention object, main technical schemes of the present invention is:
, this system comprises:
Sensing label (101), be embedded in subcutaneous, in this sensing label (101), there is the magnetic substance elastomeric material (111) that scribbles enzyme (112), described enzyme (112) decomposites corresponding derived material for the analyte response with subcutaneous, and the frequency of vibration of described magnetic substance elastomeric material (111) changes with the concentration of described derived material;
Magnetic substance detector (102), for described magnetic substance elastomeric material (111) is applied to magnetic induction, and detect the frequency of vibration of described magnetic substance elastomeric material (111), according to the corresponding relation of the frequency of vibration value prestoring and analyte concentration level, determine corresponding analyte concentration level.
In a kind of preferred embodiment, described magnetic substance detector (102) specifically comprises:
Time block (121), for according to predetermined time interval trigger magnetic induction generation module (122);
Magnetic induction generation module (122), for applying magnetic induction according to the triggering command of described time block (121) to described magnetic substance elastomeric material (111);
Detection module (123), for detection of the frequency of vibration of described magnetic substance elastomeric material (111), according to the corresponding relation of the frequency of vibration value prestoring and analyte concentration level, determines corresponding analyte concentration level.
In a kind of preferred embodiment, described system further comprises: signal recorder (103), communicate by letter with described magnetic substance detector (102), for obtaining the detected analyte concentration level of described magnetic substance detector (102), and preserve this analyte concentration level.
In a kind of preferred embodiment, described system further comprises: display, and for the described analyte concentration level detecting described in showing.
In a kind of preferred embodiment, described magnetic substance detector (102) inner side has gluing material (121), for adhering to skin.
In a kind of preferred embodiment, described analyte is glucose; Described enzyme is glucoseoxidase, and described glucoseoxidase and subcutaneous glucose response decomposite acidic materials.
In a kind of preferred embodiment, this system further comprises the wireless communication interface with wireless communication, for described analyte concentration level being uploaded to the high in the clouds of the Internet.
A kind of sensing label, this sensing label has the magnetic substance elastomeric material (111) that scribbles enzyme (112), this magnetic substance elastomeric material (111) is subcutaneous for being embedded in, described enzyme (112) decomposites corresponding derived material for the analyte response with subcutaneous, and the frequency of vibration of described magnetic substance elastomeric material (111) changes with the concentration of described derived material.
In a kind of preferred embodiment, described analyte is glucose; Described enzyme is glucoseoxidase, and described glucoseoxidase and subcutaneous glucose response decomposite acidic materials.
Compared with prior art, in the present invention, described enzyme can decomposite with subcutaneous analyte response corresponding derived material, this derived material can make the quality of magnetic substance elastomeric material and/or volume expand or the variation such as dwindle, thereby change the frequency of vibration of magnetic substance elastomeric material, the frequency of vibration that makes magnetic substance elastomeric material changes with the concentration of described derived material.Described magnetic substance detector can itself possess magnetic field, if need the analyte concentration level of human body, by described magnetic substance detector near the embedding skin that has described sensing label, so described magnetic substance detector will be applied to the magnetic field of self on described sensing label, sensing label is vibrated, and then detect the frequency of vibration of this magnetic substance elastomeric material, finally determine corresponding analyte concentration level.Therefore sensing label of the present invention does not need power drives just can work, more do not need cable to power to sensing label, very convenient wearing, patient only need to be embedded in sensing label subcutaneous, and magnetic substance detector is placed in pocket, in needs detection bodies during corresponding analyte concentration level, only need to be by magnetic substance detector near the embedding skin that has described sensing label.Therefore, after wearer has worn described sensing label, activity freely, needn't worry that cable hinders action.
Accompanying drawing explanation
Fig. 1 is the composition schematic diagram of a kind of embodiment of analyte detection system of the present invention;
Fig. 2 is the composition schematic diagram of another embodiment of analyte detection system of the present invention;
Fig. 3 is the composition schematic diagram of another embodiment of analyte detection system of the present invention;
Fig. 4 is the composition schematic diagram of another embodiment of analyte detection system of the present invention.
The specific embodiment
Below by specific embodiments and the drawings, the present invention is described in further details.
Fig. 1 is the composition schematic diagram of a kind of embodiment of analyte detection system of the present invention.Referring to Fig. 1, this analyte detection system specifically comprises:
Sensing label 101, is embedded in subcutaneously, and under the described subcutaneous skin that refers to wearer, sensing label 101 is by under embedding and skin 100 as shown in Figure 1.In this sensing label 101, there is the magnetic substance elastomeric material 111 that scribbles enzyme 112, described enzyme 112 decomposites corresponding derived material for the analyte response with subcutaneous, and the frequency of vibration of described magnetic substance elastomeric material 111 changes with the concentration of described derived material;
In the present invention, described enzyme can decomposite with subcutaneous analyte response corresponding derived material, this derived material can make the quality of magnetic substance elastomeric material and/or volume expand or the variation such as dwindle, thereby change the frequency of vibration of magnetic substance elastomeric material, the frequency of vibration that makes magnetic substance elastomeric material changes with the concentration of described derived material.Described magnetic substance detector can itself possess magnetic field, if need the analyte concentration level of human body, by described magnetic substance detector near the embedding skin that has described sensing label, so described magnetic substance detector will be applied to the magnetic field of self on described sensing label, sensing label is vibrated, and then detect the frequency of vibration of this magnetic substance elastomeric material, finally determine corresponding analyte concentration level.Therefore sensing label of the present invention does not need power drives just can work, more do not need cable to power to sensing label, very convenient wearing, patient only need to be embedded in sensing label subcutaneous, and magnetic substance detector is placed in pocket, in needs detection bodies during corresponding analyte concentration level, only need to be by magnetic substance detector near the embedding skin that has described sensing label.Therefore, after wearer has worn described sensing label, activity freely, needn't worry that cable hinders action.
Described analyte can be any subcutaneous analyte, as glucose level, ketoboidies level, acid or aqueous alkali equality etc.
In a kind of typical Application Example, described analyte detection system can be a kind of system for detecting blood sugar, and in this embodiment, described analyte is glucose; Described enzyme can be glucoseoxidase, and described glucoseoxidase and subcutaneous glucose response decomposite acidic materials.Described acidic materials can make described magnetic substance elastomeric material expand, and cause its frequency of vibration to change.Concentration of glucose in body is higher in general, and the acidic materials that decomposite are more, and described magnetic substance elastomeric material expands greatlyr, and its frequency of vibration changes larger accordingly.The glucose concentration value of this frequency of vibration just and in described body has corresponding relation so, and subcutaneous glucose concentration value and blood glucose value have and have direct corresponding relation, so in advance this corresponding relation is stored in magnetic substance detector 102, magnetic substance detector 102 needn't be connected the frequency of vibration that sensing label 101 just can be detected with described sensing label 101, then just can obtain corresponding glucose concentration value and blood glucose value according to the frequency of vibration detecting, therefore realize the detection to blood sugar for human body value.
Fig. 2 is the schematic diagram that forms by a kind of embodiment of analyte detection system of the present invention.Referring to Fig. 2, in this embodiment, described magnetic substance detector 102 specifically comprises:
Magnetic induction generation module 122, for applying magnetic induction according to the triggering command of described time block 121 to described magnetic substance elastomeric material 111;
This embodiment can realize the dynamic monitoring to bodily analytes concentration level.For example, can be by non-material of the present invention as adhesive plaster, described magnetic substance detector is fixed on the embedding skin that has a described sensing label, then described time block can trigger magnetic induction generation module according to predetermined time interval (as every 30 seconds), magnetic induction generation module applies magnetic induction to the magnetic substance elastomeric material under skin, detection module detects subcutaneous analyte concentration level according to the frequency of vibration of magnetic substance elastomeric material, so just can realize every 30 seconds and detect and obtain a subcutaneous analyte concentration level value, the dynamic monitoring of formation to subcutaneous analyte concentration level.
If for example described analyte is glucose, described analyte concentration level is blood glucose value, utilize the present invention can realize the dynamic monitoring to patient's blood glucose value, be will monitor out the current real time blood sugar of patient in every 30 seconds, this is very important to the glycemic control of diabetes, patient or doctor can adjust therapeutic scheme in time according to these real-time blood glucose values, and patient's blood glucose value was remained in normal range, improve patient health level.
Fig. 3 is the composition schematic diagram of another embodiment of analyte detection system of the present invention.Referring to Fig. 3, in this embodiment, in order to further facilitate magnetic substance detector 102 described in patient wear, described magnetic substance detector 102 inner sides have gluing material 121, for adhering to skin.So just can paste described magnetic substance detector 102 with extraneous adhesive plaster.
Fig. 4 is the composition schematic diagram of another embodiment of analyte detection system of the present invention.Referring to Fig. 4, in this embodiment, described system also further comprises: signal recorder 103, can realize wired or wireless communication with described magnetic substance detector 102, for obtaining the detected analyte concentration level of described magnetic substance detector 102, and preserve this analyte concentration level, to facilitate user to check historical analyte concentration level in the later stage.
On the basis of the embodiment of above-mentioned Fig. 2 or Fig. 3, native system can further include display, for the described analyte concentration level detecting described in showing.
On the basis of above-mentioned any embodiment, this system can further include the wireless communication interface with wireless communication, for described analyte concentration level being uploaded to the high in the clouds of the Internet.This wireless communication interface can directly be connected with magnetic substance detector 102, and magnetic substance detector 102 detects after analyte concentration level, by this wireless communication interface, in real time this analyte concentration level is uploaded to the high in the clouds of the Internet.Or this wireless communication interface also can be connected with described information-recording apparatus 102, the analyte concentration level that this information-recording apparatus can be recorded uploads to the high in the clouds of the Internet in real time or periodically.Upload to behind high in the clouds, just can realize tele-medicine, doctor can login the data that described analyte concentration level is downloaded in high in the clouds, and accordingly for patient proposes rational therapeutic scheme.
The above; be only the preferably specific embodiment of the present invention, but protection scope of the present invention is not limited to this, any people who is familiar with this technology is in the disclosed technical scope of the present invention; the variation that can expect easily or replacement, within all should being encompassed in protection scope of the present invention.
Claims (9)
1. an analyte detection system, is characterized in that, this system comprises:
Sensing label (101), be embedded in subcutaneous, in this sensing label (101), there is the magnetic substance elastomeric material (111) that scribbles enzyme (112), described enzyme (112) decomposites corresponding derived material for the analyte response with subcutaneous, and the frequency of vibration of described magnetic substance elastomeric material (111) changes with the concentration of described derived material;
Magnetic substance detector (102), for described magnetic substance elastomeric material (111) is applied to magnetic induction, and detect the frequency of vibration of described magnetic substance elastomeric material (111), according to the corresponding relation of the frequency of vibration value prestoring and analyte concentration level, determine corresponding analyte concentration level.
2. system according to claim 1, is characterized in that, described magnetic substance detector (102) specifically comprises:
Time block (121), for according to predetermined time interval trigger magnetic induction generation module (122);
Magnetic induction generation module (122), for applying magnetic induction according to the triggering command of described time block (121) to described magnetic substance elastomeric material (111);
Detection module (123), for detection of the frequency of vibration of described magnetic substance elastomeric material (111), according to the corresponding relation of the frequency of vibration value prestoring and analyte concentration level, determines corresponding analyte concentration level.
3. system according to claim 2, it is characterized in that, described system further comprises: signal recorder (103), communicate by letter with described magnetic substance detector (102), be used for obtaining the detected analyte concentration level of described magnetic substance detector (102), and preserve this analyte concentration level.
4. according to the system described in claim 2 or 3, it is characterized in that, described system further comprises:
Display, for the described analyte concentration level detecting described in showing.
5. system according to claim 1, is characterized in that, described magnetic substance detector (102) inner side has gluing material (121), for adhering to skin.
6. according to the system described in claim 1 to 5 any one, it is characterized in that,
Described analyte is glucose;
Described enzyme is glucoseoxidase, and described glucoseoxidase and subcutaneous glucose response decomposite acidic materials.
7. according to the system described in claim 1 to 5 any one, it is characterized in that, this system further comprises the wireless communication interface with wireless communication, for described analyte concentration level being uploaded to the high in the clouds of the Internet.
8. a sensing label, it is characterized in that, this sensing label has the magnetic substance elastomeric material (111) that scribbles enzyme (112), this magnetic substance elastomeric material (111) is subcutaneous for being embedded in, described enzyme (112) decomposites corresponding derived material for the analyte response with subcutaneous, and the frequency of vibration of described magnetic substance elastomeric material (111) changes with the concentration of described derived material.
9. sensing label according to claim 8, is characterized in that, described analyte is glucose; Described enzyme is glucoseoxidase, and described glucoseoxidase and subcutaneous glucose response decomposite acidic materials.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310538299.1A CN103519828B (en) | 2013-11-04 | 2013-11-04 | Analyte detection system and sensing label thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310538299.1A CN103519828B (en) | 2013-11-04 | 2013-11-04 | Analyte detection system and sensing label thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103519828A true CN103519828A (en) | 2014-01-22 |
| CN103519828B CN103519828B (en) | 2015-04-29 |
Family
ID=49922435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310538299.1A Active CN103519828B (en) | 2013-11-04 | 2013-11-04 | Analyte detection system and sensing label thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103519828B (en) |
Citations (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000060340A1 (en) * | 1999-04-06 | 2000-10-12 | Allmedicus Corporation | Electrochemical biosensor test strip, fabrication method thereof and electrochemical biosensor |
| US6579498B1 (en) * | 1998-03-20 | 2003-06-17 | David Eglise | Implantable blood glucose sensor system |
| US20040242976A1 (en) * | 2002-04-22 | 2004-12-02 | Abreu Marcio Marc | Apparatus and method for measuring biologic parameters |
| CN1708254A (en) * | 2002-10-28 | 2005-12-14 | 洛桑聚合联合学院 | Sensor system for determining the concentration of glucose in blood |
| CN1780581A (en) * | 2003-02-26 | 2006-05-31 | 马尔西奥·马克·奥雷利奥·马丁斯·阿布雷乌 | Apparatus and method for measuring biologic parameters |
| CN101341399A (en) * | 2005-12-21 | 2009-01-07 | 皇家飞利浦电子股份有限公司 | Magnetochemical sensor |
| CN101393090A (en) * | 2007-06-22 | 2009-03-25 | 索尼德国有限责任公司 | A device for processing an analyte and a method using said device |
| CN101530327A (en) * | 2009-04-20 | 2009-09-16 | 湖州艾木奇生物科技咨询服务有限公司 | Needle amperometric determination type glucose sensor for subcutaneous tissue real-time monitoring and manufacturing method thereof |
| CN101566567A (en) * | 2009-05-31 | 2009-10-28 | 武汉理工大学 | Thin-film material for optical fiber biosensor probe and preparation method thereof |
| CN102023181A (en) * | 2009-09-21 | 2011-04-20 | 清华大学 | Enzyme electrode and preparation method thereof |
| CN102105790A (en) * | 2008-07-11 | 2011-06-22 | 环球生物医疗感测器私人有限公司 | Enhanced immunoassay sensor |
| CN102378595A (en) * | 2009-03-31 | 2012-03-14 | 森西勒Pat股份公司 | Medical device for measuring an analyte concentration |
| CN102636540A (en) * | 2012-04-19 | 2012-08-15 | 湖南大学 | Glucose detection sensor, and preparation and application methods thereof |
| CN203609427U (en) * | 2013-11-04 | 2014-05-28 | 理康互联科技(北京)有限公司 | Sensing label |
| CN203609425U (en) * | 2013-11-04 | 2014-05-28 | 理康互联科技(北京)有限公司 | Analyte detecting system and sensing label of analyte detecting system |
-
2013
- 2013-11-04 CN CN201310538299.1A patent/CN103519828B/en active Active
Patent Citations (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6579498B1 (en) * | 1998-03-20 | 2003-06-17 | David Eglise | Implantable blood glucose sensor system |
| CN1349610A (en) * | 1999-04-06 | 2002-05-15 | 奥麦迪可斯株式会社 | Electrochemical biosensor test strip, fabrication method thereof and electrochemical biosensor |
| WO2000060340A1 (en) * | 1999-04-06 | 2000-10-12 | Allmedicus Corporation | Electrochemical biosensor test strip, fabrication method thereof and electrochemical biosensor |
| US20040242976A1 (en) * | 2002-04-22 | 2004-12-02 | Abreu Marcio Marc | Apparatus and method for measuring biologic parameters |
| CN1708254A (en) * | 2002-10-28 | 2005-12-14 | 洛桑聚合联合学院 | Sensor system for determining the concentration of glucose in blood |
| CN1780581A (en) * | 2003-02-26 | 2006-05-31 | 马尔西奥·马克·奥雷利奥·马丁斯·阿布雷乌 | Apparatus and method for measuring biologic parameters |
| US20110095756A1 (en) * | 2005-12-21 | 2011-04-28 | Koninklijke Philips Electronics, N.V. | Magnetochemical sensor |
| CN101341399A (en) * | 2005-12-21 | 2009-01-07 | 皇家飞利浦电子股份有限公司 | Magnetochemical sensor |
| CN101393090A (en) * | 2007-06-22 | 2009-03-25 | 索尼德国有限责任公司 | A device for processing an analyte and a method using said device |
| CN102105790A (en) * | 2008-07-11 | 2011-06-22 | 环球生物医疗感测器私人有限公司 | Enhanced immunoassay sensor |
| CN102378595A (en) * | 2009-03-31 | 2012-03-14 | 森西勒Pat股份公司 | Medical device for measuring an analyte concentration |
| CN101530327A (en) * | 2009-04-20 | 2009-09-16 | 湖州艾木奇生物科技咨询服务有限公司 | Needle amperometric determination type glucose sensor for subcutaneous tissue real-time monitoring and manufacturing method thereof |
| CN101566567A (en) * | 2009-05-31 | 2009-10-28 | 武汉理工大学 | Thin-film material for optical fiber biosensor probe and preparation method thereof |
| CN102023181A (en) * | 2009-09-21 | 2011-04-20 | 清华大学 | Enzyme electrode and preparation method thereof |
| CN102636540A (en) * | 2012-04-19 | 2012-08-15 | 湖南大学 | Glucose detection sensor, and preparation and application methods thereof |
| CN203609427U (en) * | 2013-11-04 | 2014-05-28 | 理康互联科技(北京)有限公司 | Sensing label |
| CN203609425U (en) * | 2013-11-04 | 2014-05-28 | 理康互联科技(北京)有限公司 | Analyte detecting system and sensing label of analyte detecting system |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103519828B (en) | 2015-04-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20220330856A1 (en) | Analyte monitoring devices and methods | |
| US10806384B2 (en) | Kit for determining an analyte concentration | |
| US20220211305A1 (en) | Self-powered analyte sensor and devices using the same | |
| EP3677182B1 (en) | Analyte monitoring device and methods | |
| CN105873514A (en) | Continuous glucose collecting apparatus and main machine | |
| US20220338780A1 (en) | Self-contained eeg recording system | |
| US20200205694A1 (en) | Analyte sensor with impedance determination | |
| WO2007098228A3 (en) | System and method of monitoring physiological signals | |
| CN203609425U (en) | Analyte detecting system and sensing label of analyte detecting system | |
| CN203609427U (en) | Sensing label | |
| CN203609426U (en) | Analyte detecting system and sensing label of analyte detecting system | |
| CN203576510U (en) | Analyte detection system | |
| CN203576512U (en) | Analyte sensing device | |
| CN103519828B (en) | Analyte detection system and sensing label thereof | |
| CN103519829B (en) | Analyte detection system and sensing label thereof | |
| CN105517491A (en) | Continuous glucose monitoring system and monitoring terminal | |
| CN105615897B (en) | A kind of blood sugar monitor and its monitoring method | |
| CN105326482B (en) | The method and apparatus for recording physiological signal | |
| CN110393852A (en) | A kind of radioactive prospecting instrument is pushed pin working state monitoring system | |
| CN203802472U (en) | Dynamic monitor for blood glucose | |
| KR20190085708A (en) | Healthcare system and method interlocked with bed | |
| KR101752303B1 (en) | Implantable biomaterial sensing device | |
| CN104720763A (en) | Pulse detector | |
| CN117243567A (en) | Channel signal detection device based on accelerometer and channel signal detection method thereof | |
| KR20190014875A (en) | Invasive continuous glucose monitoring system applying reverse iontophoresis and continuous glucose monitoring method using thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| ASS | Succession or assignment of patent right |
Owner name: LIKANG HULIAN TECHNOLOGY (BEIJING) CO., LTD. Free format text: FORMER OWNER: LI XIU Effective date: 20141203 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 100012 CHAOYANG, BEIJING TO: 100120 XICHENG, BEIJING |
|
| TA01 | Transfer of patent application right |
Effective date of registration: 20141203 Address after: 100120 Beijing City, Xicheng District five No. 5 North Sheng Hui Garden 5 503 unit Applicant after: LIKANG HULIAN TECHNOLOGY (BEIJING) CO.,LTD. Address before: 100012 Beijing city Chaoyang District, Beijing Youth City Building No. 19 361 Applicant before: Li Xiu |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20200623 Address after: Building 604, building 1, chengdongmingmen, East District, Zhongshan City, Guangdong Province Patentee after: Pan Xinhao Address before: 510000 No.106 Fengze East Road, Nansha District, Guangzhou City, Guangdong Province (self compiled Building 1) x1301-f7238 (cluster registration) (JM) Patentee before: Guangzhou jikrypton Technology Service Co.,Ltd. Effective date of registration: 20200623 Address after: 510000 No.106 Fengze East Road, Nansha District, Guangzhou City, Guangdong Province (self compiled Building 1) x1301-f7238 (cluster registration) (JM) Patentee after: Guangzhou jikrypton Technology Service Co.,Ltd. Address before: 100120 Beijing City, Xicheng District five No. 5 North Sheng Hui Garden 5 503 unit Patentee before: LIKANG HULIAN TECHNOLOGY (BEIJING) Co.,Ltd. |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20201230 Address after: No.1 Weier Road, Shanggang Industrial Park, Jianhu County, Yancheng City, Jiangsu Province Patentee after: Jianhu Shanggang Industrial Park Service Co.,Ltd. Address before: 528400 room 604, building 1, Chengdong Mingmen, East District, Zhongshan City, Guangdong Province Patentee before: Pan Xinhao |