CN103285439A - Hydrogen reduction apparatus for dialyzate or original solution - Google Patents
Hydrogen reduction apparatus for dialyzate or original solution Download PDFInfo
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- CN103285439A CN103285439A CN2012103062481A CN201210306248A CN103285439A CN 103285439 A CN103285439 A CN 103285439A CN 2012103062481 A CN2012103062481 A CN 2012103062481A CN 201210306248 A CN201210306248 A CN 201210306248A CN 103285439 A CN103285439 A CN 103285439A
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Abstract
The subject of the invention is to manufacture dialyzate having low oxidation-reduction potential. A hydrogen reduction apparatus (1) for the dialyzate or original solution provided by the invention dissolves hydrogen in solution of the dialyzate or the dialyzate original solution and manufactures the reduction dialyzate or the reduction dialyzate original solution having the relatively low oxidation-reduction potential. The apparatus comprises a degassing unit, a second membrane assembly (40) and a pressure tank (70), wherein the degassing unit degases in the solution of the dialyzate or the dialyzate original solution and comprises at least one first membrane assembly (30); and the second membrane assembly (40) is connected with one side of the degassing unit transmitting the solution of the dialyzate or the dialyzate original solution. The hydrogen isolated by a membrane can pass from holes (102) formed on the membrane and is mixed in the solution of the dialyzate or the dialyzate original solution. The pressure tank (70) is connected with a downstream side of the second membrane assembly (40) and is used for pressurizing the solution of the dialyzate or the dialyzate original solution, so that dissolution concentration of the hydrogen contained in the solution of the dialyzate or the dialyzate original solution is raised.
Description
Technical field
The present invention relates to the dialysis solution or the stock solution hydrogen reduction device that reduce for the stock solution that dialysis solution or dialysis solution are used.
Background technology
Hemodialysis is widely known by the people as the method for the blood purification function of manually carrying out kidney.There is report to claim world's hemodialysis patients in 2007 up to about 2,000,000 people, and the trend that increases is year by year arranged.Hemodialysis is the Therapeutic Method that carries out following operation continuously, that is, make and utilize pump etc. to be drawn to the dialyser of the aggregation of external blood by having doughnut and the refuse in the blood is removed, and make blood turn back to operation in the body again.The needs of patients of suffering from renal dysfunction goes the treatment that two, three times hospital accepts the hemodialysis of stipulated time weekly.
Dialysis solution has the various ions that comprise in the blood and the composition of glucose, and is a large amount of stock solutions are mixed and to modulate or be dissolved in the water (RO water) and will a large amount of these stock solutions after having made stock solution mix and modulate at the former powder with pulverulence.Stock solution or former powder (below be referred to as " former dose ") generally are made of the A agent of the salt that comprises sodium, potassium, calcium, magnesium etc. and the B agent that comprises bicarbonate.This is to generate insoluble carbonate because of the calcium ion of bivalence or magnesium ion and bicarbonate reaction.Glucose is pre-mixed in above-mentioned A agent.
Constitute glucose time dependent ground degraded contained in former dose the above-mentioned A agent and generate glucose degradation product (for example Biformyl).When the dialysis solution that will contain the glucose degradation product supplies in treatment, thereby can cause that the oxidative stress to human body causes that the situation of cell damage or chronic inflammatory disease is by cognition.As the method that addresses this problem, proposed in advance when the modulation dialysis solution, to be dissolved with the hydrogen of ormal weight in the employed water (RO water), and the dilution water that will be dissolved with hydrogen is blended in such method (for example with reference to patent documentation 1 and patent documentation 2) in former dose of the dialysis solution.
[technical literature formerly]
[patent documentation]
Patent documentation 1: Japanese communique, spy open 2007-289267 number
Patent documentation 2: Japanese communique, spy open 2010-063629 number
Summary of the invention
But, owing to hydrogen is difficult to be dissolved in the water in a large number, therefore, even hydrogen being foamed or obtaining under the situation of electrolytic reduction water (ERW) at cathode side by electrolysis, also be difficult to improve the hydrogen concentration in the water in dilution water.Because there is very big deviation in the containing ratio of contained glucose degradation product in former dose of the dialysis solution, therefore, for former dose of the high dialysis solution of the containing ratio of glucose degradation product, utilize the micro-hydrogen that is dissolved in the RO water glucose degradation product fully can't be reduced.
The present invention makes in order to address the above problem, and its purpose is to make the low dialysis solution of oxidation-reduction potential.
In order to reach above-mentioned purpose, dialysis solution of the present invention or stock solution hydrogen reduction device, be that hydrogen is dissolved in the solution of former dose of dialysis solution or dialysis solution, thereby the device of the reduction dialysis solution that the manufacturing oxidation-reduction potential becomes lower or reduction dialysis solution stock solution, it possesses degas module, second membrane module and forbay, wherein, degas module is the unit that the gas in the solution of former dose of dialysis solution or dialysis solution is outgased, and comprises first membrane module at least; Second membrane module is connected a side of carrying the solution of former dose of dialysis solution or dialysis solution from degas module, thereby and can make the hole of hydrogen on being formed at this film that exist across film by the solution that is blended in former dose of dialysis solution or dialysis solution; Forbay is connected the downstream of second membrane module, and is used for that solution to former dose of dialysis solution or dialysis solution pressurizes and the concentration of ordinary dissolution that improves the contained hydrogen of the solution of former dose of dialysis solution or dialysis solution.
Other dialysis solution of the present invention or stock solution hydrogen reduction device are in the downstream of forbay and then be connected with tertiary membrane assembly with the gas degassing in the solution of former dose of the dialysis solution in this downstream or dialysis solution.
Other dialysis solution of the present invention or stock solution hydrogen reduction device, and then possesses following such structure, that is, the pipe arrangement of supplying gas of tertiary membrane assembly is connected to first membrane module carries on the liquor charging pipe arrangement of solution of former dose of dialysis solution or dialysis solution, thereby carry out the remix of hydrogen.
Other dialysis solution of the present invention or stock solution hydrogen reduction device, and then be connected with for the hydrogen gas supplying apparatus of supplying with hydrogen at second membrane module.
(invention effect)
According to the present invention, can make the low dialysis solution of oxidation-reduction potential.
Description of drawings
Fig. 1 is the dialysis solution that relates to of embodiments of the present invention or the ideograph of stock solution hydrogen reduction device.
Fig. 2 roughly represents to utilize stock solution before dialysis solution shown in Figure 1 or stock solution hydrogen reduction device mix from hydrogen to make the flow chart of the flow process of the reduction dialysis solution stock solution after the hydrogen reduction.
Fig. 3 represents the structure (3A) of second membrane module shown in Figure 1 and the ideograph (3B) that describes for the structure of the hydrogen that will exist across the film that constitutes the doughnut sidewall being mixed with the stock solution of the dialysis solution of doughnut inside and make hydrogen be dissolved in stock solution.
Fig. 4 be various electrolyte (A agent) that expression will contain glucose when being dissolved in the RO water (hydrogen water) that contains hydrogen hydrogen concentration and the chart of oxidation-reduction potential variation separately.
Fig. 5 is the hydrogen concentration of bicarbonate (B agent) when being dissolved in hydrogen water and the chart of oxidation-reduction potential variation separately that expression will not contain glucose.
(symbol description)
1 dialysis solution or stock solution hydrogen reduction device
12 pipes (liquor charging pipe arrangement)
20 first pumps (part of degas module)
30 first membrane modules (part of degas module)
40 second membrane modules
50 apparatus for electrolyzing (example of hydrogen gas supplying apparatus)
70 forbays
80 tertiary membrane assemblies
82 pipes (pipe arrangement of supplying gas)
102 holes
The specific embodiment
Below, describe with reference to the suitable embodiment of accompanying drawing to dialysis solution of the present invention or stock solution hydrogen reduction device.
At first, the dialysis solution that becomes the object that dissolves hydrogen is described for former dose.Former dose of dialysis solution is made of A agent and the B agent that comprises bicarbonate, and wherein, above-mentioned A agent comprises salt and the glucose of sodium, potassium, calcium, magnesium etc.Owing to the calcium ion of bivalence or magnesium ion and bicarbonate reaction generate insoluble carbonate, therefore, before the preparation dialysis solution with A agent and B agent separately.In this embodiment, become former dose of object of dissolving hydrogen and be the A agent.
Fig. 1 is the dialysis solution that relates to of embodiments of the present invention or the ideograph of stock solution hydrogen reduction device.
Dialysis solution shown in Figure 1 or stock solution hydrogen reduction device 1, thus be the device that hydrogen is dissolved in make in the solution of former dose of dialysis solution the reduction dialysis solution stock solution that oxidation-reduction potential becomes lower.Dialysis solution or stock solution hydrogen reduction device 1 are connected with filter 10, first pump 20, first membrane module 30, second membrane module 40, second pump 60, forbay 70 and tertiary membrane assembly 80 in turn and constitute from the discharge side (downstream) of the reduction dialysis solution stock solution of supply side (upstream side) after being dissolved with hydrogen of the solution (following only be called " stock solution ") of former dose of dialysis solution.Second membrane module 40 is connected with apparatus for electrolyzing 50 as an example of hydrogen gas supplying apparatus in another circuit different with above-mentioned circuit.
Filter 10 has the function that shot-like particle contained in the stock solution is filtered out.Stock solution is being carried out under the situation of above-mentioned filtration treatment, also filter 10 can be set in dialysis solution or the stock solution hydrogen reduction device 1, still, stock solution is not being carried out under the situation of above-mentioned filtration treatment filter 10 being set preferably.Filter 10 is so long as the device that unwanted solid can be separated, and then its form is not limit, but is preferably cartridge filter (cartridge type filter).In addition, under situation about antibacterial or endotoxin also need be removed, also can use membrane module as filter 10.
Stock solution enters into filter 10 and after this is filtered, enters into first pump 20 from filter 10 via pipe 12 by managing 5.Pipe 12 is provided with undergauge parts 15 in inside, these undergauge parts 15 have the function of the internal diameter that dwindles pipe 12.Therefore, the suction side zone of (positive front) before first pump 20 can be formed negative pressure.First pump 20 has and will forcibly be sent to the function of first membrane module, 30 sides by the stock solution behind the filter 10.In this embodiment, first membrane module 30 and first pump 20 constitute the degas module that the gas in the stock solution (air etc.) is outgased.But, under the situation that has first pump 20 other liquid feeding devices in addition, also can only constitute degas module by first membrane module 30.
First membrane module 30 has the function that gas contained in the stock solution is separated from stock solution.The inside of first membrane module 30 has the doughnut that is made of hydrophilic film in a large number.Therefore, stock solution can be optionally the inside of doughnut in first membrane module 30 pass the barrier film (septum) of doughnut and move to the outside of doughnut.On the other hand, contained gas can't be by the barrier film of doughnut in the stock solution, and is transferred to the outside of first membrane module 30 that links to each other with the inside of doughnut from the inside of doughnut.
Be separated by predetermined distance on the length direction of first membrane module 30 and be provided with the outlet of two places.This two places outlet is connected with pipe 36 with pipe 35.Pipe 36 and pipe 35 interflow, and from its position, interflow with manage 37 and be connected, thereby be connected the upstream side of second membrane module 40.Pipe 36 arranges in order to prevent following situation, that is, stock solution accumulates diseaseful situation near the existing delay position outlet of first membrane module 30 and in this delay position, still, when not being formed with the delay position near this outlet, pipe 36 can be set also.
In addition, first membrane module 30 from the outlet that links to each other with the inside of doughnut with manage 32 and be connected.Pipe 32 is connected on the filter 10.The doughnut of first membrane module 30 not only makes gas pass through from its inside, and liquid is passed through from its inside.That is to say, be not that all stock solutions are all passed through from the barrier film of doughnut.Therefore, the both sides of contained gas can be flowed in pipe 32 in stock solution and the stock solution.Gas can be discharged the outside to dialysis solution or stock solution hydrogen reduction device 1 via the pipe 33 that is connected filter 10 tops.Since pipe 33 be connected with valve 34 midway, therefore, can come the discharge of adjustments of gas by the switching of valve 34.
Be separated by predetermined distance on the length direction of second membrane module 40 and be provided with two place's entrances.An entrance in this two places entrance blocked a shot (cap) block.Another entrance is hydrogen supply port 41, and links to each other with apparatus for electrolyzing 50 as an example of hydrogen gas supplying apparatus via pipe 42.Apparatus for electrolyzing 50 is water electrolysis to be produced the device of hydrogen and oxygen, and the electrode side that produces hydrogen is connected with pipe 42.
The downstream of second membrane module 40 is connected on the pipe 43.The inside of a large amount of doughnuts in pipe 43 and second membrane module 40 links to each other.Pipe 43 is connected on the forbay 70, and is connected with second pump 60 midway at pipe 43.At this, second pump 60 is connected the downstream of second membrane module 40, and is the stock solution that will contain hydrogen is transported to forbay 70 from second membrane module 40 device.Hydrogen enters into the inside of doughnut after through pipe 42 and the barrier film by a large amount of doughnuts in second membrane module 40 from apparatus for electrolyzing 50.By managing 37 stock solutions that are fed in second membrane module 40, mix with hydrogen in being fed into second membrane module 40.The liquid that contains hydrogen enters into forbay 70 from second membrane module 40 via second pump 60.About mixing of the stock solution in second membrane module 40 and hydrogen, be described in detail afterwards.
Forbay 70 is connected the downstream of second membrane module 40, the downstream of second pump 60 more particularly, thereby and is for to entering into the pressurize container of the concentration of ordinary dissolution that improves the contained hydrogen of solution of solution in the case.In addition, forbay 70 is connected with the tertiary membrane assembly 80 that is configured in its downstream via pipe 72.Pipe 72 be provided with pressure-regulating valve 75 midway.Can regulate pressure in the forbay 70 by the adjusting of pressure-regulating valve 75.Be fed into the stock solution that contains hydrogen (hereinafter referred to as " reduction dialysis solution stock solution ") in the forbay 70, can improve the dissolubility of hydrogen according to pressure.
Tertiary membrane assembly 80 is to be connected the downstream of forbay 70 and will to reduce the member that remaining gas (hydrogen) in the dialysis solution stock solution outgases.Tertiary membrane assembly 80 has the structure identical with first membrane module 30.Reduction dialysis solution stock solution can be optionally the inside of doughnut in the tertiary membrane assembly 80 pass the barrier film of the fine saturating dimension of hollow and move to the outside of doughnut.On the other hand, what mix with reduction dialysis solution stock solution is that the gas of representative can't be with the form of the bubble barrier film by doughnut with hydrogen, but is transferred to the outside of the tertiary membrane assembly 80 that links to each other with the inside of doughnut from the inside of doughnut.
Be separated by predetermined distance on the length direction of tertiary membrane assembly 80 and be provided with the outlet of two places.This two places outlet links to each other with pipe 84 with pipe 83.Pipe 84 and pipe 83 interflow.Reduction dialysis solution stock solution is transferred to subsequent processing from managing 83.In addition, tertiary membrane assembly 80 is connected with pipe 82 as the pipe arrangement of supplying gas from the outlet that links to each other with the inside of doughnut.Pipe 82 links to each other with the pipe 12 that is connected filter 10 downstreams midway.The doughnut of tertiary membrane assembly 80 not only makes hydrogen pass through from its inside, and liquid is passed through from its inside.That is to say, be not all reduction dialysis solution stock solution all the barrier film of the doughnut in the tertiary membrane assembly 80 pass through.
Therefore, the mobile both sides that hydrogen contained in reduction dialysis solution stock solution and the reduction dialysis solution stock solution is arranged in pipe 82.Hydrogen is transported in first membrane module 30 through pipe 12.That is, be connected in first membrane module 30 by the pipe 82 with tertiary membrane assembly 80 and carry on the pipe 12 as the liquor charging pipe arrangement of stock solutions, and carry out the remix of hydrogen.By like this, can effectively utilize hydrogen.
At this, used apparatus for electrolyzing 50 as hydrogen gas supplying apparatus, still, also can not use apparatus for electrolyzing 50 and use the High Pressure Hydrogen gas cylinder that is packaged with hydrogen with the form of high pressure.In addition, also can dispose tertiary membrane assembly 80.In addition, also the pipe 82 that comprises the hydrogen that is separated by tertiary membrane assembly 80 can be connected on the pipe 37 rather than manage on 12.In addition, thus also pipe 82 can be connected pipe makes on 32 pipe 82 open wide to the outside of dialysis solution or stock solution hydrogen reduction device 1.
And then pipe 32 also can open wide rather than be connected on the filter 10 to the outside of dialysis solution or stock solution hydrogen reduction device 1.Allocation position and the quantity of first pump 20 and second pump 60 do not have any restriction, as long as can be from first membrane module 30 to forbay 70 carry out liquor charging and forbay 70 is pressurized to more than the atmospheric pressure, just can go up the pump of configuration any amount at an arbitrary position.In addition, forbay 70 also can be the roughly the same tubular part of pipe of diameter and its entrance side or outlet side.
Fig. 2 roughly represents to utilize stock solution before dialysis solution shown in Figure 1 or stock solution hydrogen reduction device mix from hydrogen to make the flow chart of the flow process of the reduction dialysis solution stock solution after the hydrogen reduction.
At former dose of dialysis solution during for liquid (this state is called " stock solution "), this stock solution is transported in first membrane module 30 via pipe 5, thereby directly is conducted to during the degassing handles.On the other hand, when former dose of dialysis solution was powder, will this former dose being dissolved in the water formed liquid (will form aqueous material and be also referred to as " stock solution "), and this stock solution is transported in first membrane module 30 via pipe 5, thereby was conducted to during the degassing handles.
It is the processing that the dissolved oxygen in the stock solution etc. is removed that the degassing is handled, help after the hydrogen dissolution process in the concentration of hydrogen in the liquid of raising after being dissolved in the hydrogen dissolution process.Stock solution after the degassing is handled is then mixed with hydrogen, thereby is conducted in the hydrogen dissolution process.Hydrogen is to carry out in second membrane module 40 to the dissolving in the stock solution, and also carries out under the environment under high pressure in forbay 70.The catabolite (for example Biformyl) that hydrogen helps the glucose degradation in the stock solution is generated reduces.
The reduction dialysis solution stock solution that is sent to the downstream from forbay 70, contain the hydrogen that is dissolved in the reduction dialysis solution stock solution and remains the molecularity that exists after the reduction of degradation of glucose product sometimes.Therefore, under this situation, for this hydrogen is removed, and carry out the operation of utilizing tertiary membrane assembly 80 optionally hydrogen to be separated from reduction dialysis solution stock solution.
Fig. 3 represents the structure (3A) of second membrane module shown in Figure 1 and the ideograph (3B) that describes for the structure of the hydrogen that will exist across the film that constitutes the doughnut sidewall being mixed with the dialysis solution stock solution of doughnut inside and make hydrogen be dissolved in stock solution.
When the downstream at doughnut 101 was moved second pump 60, the downstream of doughnut 101 and the inboard of sidewall became negative pressure.Consequently, the stock solution in the doughnut 101 flows towards the direction of second pump 60, and hydrogen 102 enters the inside of doughnut 101 and flows with the direction of stock solution towards second pump 60 from the hole.
Generally speaking, when making gas dissolving in liquid, make method that gas foams in liquid by cognition in view of dissolving difficulty.But in common foaming method, the size of bubble is big to millimeter level～hundreds of micron orders, also inadequately little under the situation in the instantaneous stock solution that is dissolved in dialysis solution with making the hydrogen high concentration as present embodiment.Therefore, in the present embodiment, will have the sidewall of doughnut 101 in the hole 102 of a large amount of dust levels, utilize as the device that in stock solution, produces the hydrogen gas bubbles V littler than hole 102.Consequently, can in stock solution, form minimum hydrogen gas bubbles V (than the little bubble V of the diameter in hole 102), thereby hydrogen is dissolved in the stock solution with higher concentration.
Like this, in the present embodiment, a large amount of doughnuts 101 are banded together, and the sidewall at each doughnut 101 arranges a large amount of hole 102, generates the dust level bubble littler than the diameter in hole 102 thereby forcibly make from managing 42 hydrogen that enter into sleeve pipe 100 in the stock solution of doughnut 101.Therefore, can enlarge markedly the contact area of stock solution and hydrogen, hydrogen is dissolved in the stock solution with higher concentration.
In addition, in the above-described embodiment, utilize the example that hydrogen is dissolved in the stock solution (A agent) to be illustrated, still, in the dialysis solution that hydrogen is dissolved in the B agent by replacing the A agent or is made by A agent and B agent and reduce, also can significantly reduce the oxidation-reduction potential of dialysis solution.
[embodiment]
Below, embodiments of the invention are described.In addition, the present invention is not limited to following embodiment.
＜1. preliminary experiment 〉
Fig. 4 be various electrolyte (A agent) that expression will contain glucose when being dissolved in the RO water (reverse osmosis water, reverse osmosis water) (hereinafter referred to as " hydrogen water (Hydrogen water) ") that contains hydrogen hydrogen concentration and the chart of oxidation-reduction potential variation separately.Fig. 5 is the hydrogen concentration of bicarbonate (B agent) when being dissolved in hydrogen water and the chart of oxidation-reduction potential variation separately that expression will not contain glucose.
The oxidation-reduction potential of various liquid is used the portable pH meter (model: HM-21P) measure of DKK Toa Corp.'s system.The concentration of the hydrogen that dissolves is used the TRUSTLEX of Co., Ltd. (TRUSTLEX Co., Ltd.) Zhi portable dissolved hydrogen measuring instrument (model: ENH-1000) measure.
In the time will containing the various electrolyte of glucose (A agent) 143g and be dissolved among the hydrogen water 500g that oxidation-reduction potential is 1.47ppm for-795mV, hydrogen concentration, as shown in Figure 4,5 minutes rear oxidation reduction potentials become+and 73mV, hydrogen concentration become 0.45ppm, and 10 minutes rear oxidation reduction potentials become+and 69mV, hydrogen concentration become 0.18ppm.As time goes on the result when being dissolved with the A agent in hydrogen water, begins after firm dissolving as can be known soon thus, and hydrogen concentration reduces, and oxidation-reduction potential is just become by negative.
On the other hand, when the bicarbonate that will not contain glucose (B agent) 35g is dissolved among the hydrogen water 500g that oxidation-reduction potential is 1.20ppm for-642mV, hydrogen concentration, as shown in Figure 5,5 minutes rear oxidation reduction potentials become-and 677mV, hydrogen concentration become 1.14ppm, and 10 minutes rear oxidation reduction potentials become-and 665mV, hydrogen concentration become 1.08ppm.As time goes on the result when having mixed the B agent in hydrogen water, begins after firm dissolving as can be known soon thus, and hydrogen concentration significantly changes, and oxidation-reduction potential does not also significantly change and keeps negative current potential.
＜2. experimental example 〉
(1) sample
Prepare to contain the various electrolyte (A agent) of glucose as former dose of dialysis solution and do not contained the bicarbonate (B agent) of glucose.As a comparison, also to tap water, measure by the water behind the RO film (reverse osmosis membrane) (RO water).
(2) experiment content
Following a)～g) oxidation-reduction potential of seven kinds of samples is measured: a) A agent, b) B agent, c) tap water, d) RO water, e) modification A agent, f after using dialysis solution shown in Figure 1 or stock solution hydrogen reduction device with the hydrogen dissolving) dialysis solution, the g of the existing type of only A agent and B agent being mixed) with modification A agent and the mixed modification dialysis solution of B agent.In the measurement of oxidation-reduction potential, used＜1. preliminary experiment〉in employed pH meter.
Making e) during modification A agent, used the dialyser PES-25S α (membrane area is 2.5m2) of Nipro Corp (Nipro Corporation) system as second membrane module.In addition, used apparatus for electrolyzing in second membrane module, to supply with hydrogen as hydrogen gas supplying apparatus.Forbay uses the cylindrical vessel of the vinyl chloride system of 17L, and keeps intrinsic pressure condition for 0.3MPa to carry out.
(3) result
The oxidation-reduction potential of a)～g) various samples is shown in the table 1.
[table 1]
| Sample | Oxidation-reduction potential (mV) |
| A) A agent | +429 |
| B) B agent | +316 |
| C) tap water | ＞+600 |
| D) RO water | +425 |
| E) modification A agent | -498 |
| F) dialysis solution of existing type | +320 |
| G) modification dialysis solution | +70 |
As shown in table 1, by the dissolving of hydrogen, the oxidation-reduction potential of modification A agent is reduced to-498mV from+429mV.With the oxidation-reduction potential of the modification dialysis solution after this modification A agent, B agent and the mixing of RO water and the dilution be+70mV.This value (+70mV) be the oxidation-reduction potential that is starkly lower than the dialysis solution of existing type (+320mV) value.Thus, reduce by hydrogen is dissolved in the A agent, can significantly reduce the oxidation-reduction potential of dialysis solution.
(utilizing on the industry probability)
The present invention can be used in the industry of making the low dialysis solution of oxidation-reduction potential.
Claims (4)
1. a dialysis solution or stock solution hydrogen reduction device, it is that hydrogen is dissolved in the solution of former dose of dialysis solution or dialysis solution, thereby makes reduction dialysis solution that oxidation-reduction potential becomes lower or the device of reduction dialysis solution stock solution, it is characterized in that possessing:
Degas module, it is the unit that the gas in the solution of former dose of described dialysis solution or described dialysis solution is outgased, and comprises first membrane module at least;
Second membrane module, it is connected a side of carrying described dialysis solution or described solution from described degas module, thereby and can make the hole of hydrogen on being formed at this film that exists across film by being blended in described dialysis solution or the described solution; And
Forbay, it is connected the downstream of described second membrane module, and is used for described dialysis solution or described solution are pressurizeed and improves the concentration of ordinary dissolution of the contained hydrogen of described dialysis solution or described solution.
2. dialysis solution as claimed in claim 1 or stock solution hydrogen reduction device is characterized in that,
In the downstream of described forbay, and then be connected with the described dialysis solution in this downstream or the tertiary membrane assembly of the degassing of the gas in the described solution.
3. dialysis solution as claimed in claim 1 or 2 or stock solution hydrogen reduction device is characterized in that,
The pipe arrangement of supplying gas of described tertiary membrane assembly is connected to described first membrane module carries on the liquor charging pipe arrangement of described dialysis solution or described solution, thereby carry out the remix of hydrogen.
4. dialysis solution as claimed in claim 1 or 2 or stock solution hydrogen reduction device is characterized in that, are connected with for the hydrogen gas supplying apparatus of supplying with hydrogen at described second membrane module.
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| Application Number | Priority Date | Filing Date | Title |
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| JP2012038694A JP5872321B2 (en) | 2012-02-24 | 2012-02-24 | Dialysate / raw solution hydrogen reduction system |
| JP2012-038694 | 2012-02-24 |
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| CN103285439A true CN103285439A (en) | 2013-09-11 |
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| CN109475674A (en) * | 2016-07-27 | 2019-03-15 | 日本多宁股份有限公司 | The cleaning method of dialyzate manufacturing device |
| CN110665080A (en) * | 2019-07-02 | 2020-01-10 | 郭俭 | Method for filling hydrogen into blood needing dialysis |
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| JP2015177911A (en) * | 2014-03-19 | 2015-10-08 | 株式会社日本トリム | Manufacturing apparatus of dialysate |
| JP5840248B2 (en) * | 2014-03-19 | 2016-01-06 | 株式会社日本トリム | Dialysate production equipment |
| US20210393862A1 (en) * | 2018-10-01 | 2021-12-23 | Nihon Trim Co., Ltd. | Dialysis solution production device |
| JP7292957B2 (en) * | 2019-04-26 | 2023-06-19 | オルガノ株式会社 | Dissolved gas water production device and method |
| JP7324904B1 (en) | 2022-06-10 | 2023-08-10 | 株式会社日本トリム | water treatment equipment |
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| CN102348496A (en) * | 2009-03-31 | 2012-02-08 | 栗田工业株式会社 | Device for supplying water containing dissolved gas and process for producing water containing dissolved gas |
| CN102145931A (en) * | 2011-02-24 | 2011-08-10 | 孙学军 | Method and device for improving dissolved amount of hydrogen in water by pressure |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109475674A (en) * | 2016-07-27 | 2019-03-15 | 日本多宁股份有限公司 | The cleaning method of dialyzate manufacturing device |
| CN110665080A (en) * | 2019-07-02 | 2020-01-10 | 郭俭 | Method for filling hydrogen into blood needing dialysis |
Also Published As
| Publication number | Publication date |
|---|---|
| JP5872321B2 (en) | 2016-03-01 |
| JP2013172821A (en) | 2013-09-05 |
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Application publication date: 20130911 |