CN103267859A - Application of CRISP1 (cystein-rich secretory protein 1) test paper for diagnosing gingival carcinoma - Google Patents
Application of CRISP1 (cystein-rich secretory protein 1) test paper for diagnosing gingival carcinoma Download PDFInfo
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- CN103267859A CN103267859A CN201310190889XA CN201310190889A CN103267859A CN 103267859 A CN103267859 A CN 103267859A CN 201310190889X A CN201310190889X A CN 201310190889XA CN 201310190889 A CN201310190889 A CN 201310190889A CN 103267859 A CN103267859 A CN 103267859A
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- test paper
- crisp1
- saliva
- secretory protein
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Description
Diagnosis index | AUC | Sensitivity | Specificity | False positive rate | False negative rate | The Youden index |
Urine CRISP1 10 ng/ml | 0.829 | 86.5% | 41.3% | 60.7% | 12.9% | 0.278 |
Urine CRISP1 40 ng/ml | 0.829 | 75.4% | 85.1% | 12.9% | 28.6% | 0.605 |
Claims (1)
- One kind diagnose gingival carcinoma be rich in the application of halfcystine secretory protein 1 test paper in the medicine equipment of preparation diagnosis gingival carcinoma, described test paper, comprise base plate, sample pad, the gold size pad, cellulose nitrate rete and absorbent paper layer, cover sample pad on the described base plate successively, the gold size pad, cellulose nitrate rete and absorbent paper layer, contain bovine serum albumin(BSA)-saliva on the described cellulose nitrate rete and be rich in the p-wire of halfcystine secretory protein 1 conjugate and the nature controlling line that anti-mouse two resists, containing collaurum and anti-saliva on the described gold size pad is rich in halfcystine secretory protein 1 antibody and is combined the gold that forms and marks anti-saliva and be rich in halfcystine secretory protein 1 antibody complex, the diagnosis sample of described test paper is saliva, and the detection fault value of described test paper is that saliva is rich in halfcystine secretory protein 1 concentration 10-40ng/ml.
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CN201310190889.XA CN103267859B (en) | 2013-05-22 | 2013-05-22 | Application of CRISP1 (cystein-rich secretory protein 1) test paper for diagnosing gingival carcinoma |
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CN201310190889.XA CN103267859B (en) | 2013-05-22 | 2013-05-22 | Application of CRISP1 (cystein-rich secretory protein 1) test paper for diagnosing gingival carcinoma |
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CN103267859A true CN103267859A (en) | 2013-08-28 |
CN103267859B CN103267859B (en) | 2015-03-11 |
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CN201310190889.XA Expired - Fee Related CN103267859B (en) | 2013-05-22 | 2013-05-22 | Application of CRISP1 (cystein-rich secretory protein 1) test paper for diagnosing gingival carcinoma |
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Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030027178A1 (en) * | 2001-03-16 | 2003-02-06 | George Vasmatzis | Methods and kits for determining a cancer diagnosis and prognosis |
US20050282729A1 (en) * | 2002-05-28 | 2005-12-22 | Regents Of The Univeristy Of Minnesota | Crisp polypeptides as contraceptives and inhibitors of sperm capacitation |
WO2007092713A2 (en) * | 2006-02-02 | 2007-08-16 | Trustees Of The University Of Pennsylvania | Microfluidic system and method for analysis of gene expression in cell-containing samples and detection of disease |
US20100183562A1 (en) * | 2007-02-02 | 2010-07-22 | Istituto Nazionale Di Genetica Molecolare-Ingm | Sub -population of hematopoietic stem cells that express the crisp-1 protein |
CA2693546A1 (en) * | 2009-11-03 | 2011-05-03 | Universite Laval | Detection of human cysteine-rich secretory protein (crisp1) in semen and medical applications related thereto |
CN102914658A (en) * | 2012-10-24 | 2013-02-06 | 高维强 | Application of CRISP3 protein on diagnosis and treatment of prostate cancer |
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2013
- 2013-05-22 CN CN201310190889.XA patent/CN103267859B/en not_active Expired - Fee Related
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030027178A1 (en) * | 2001-03-16 | 2003-02-06 | George Vasmatzis | Methods and kits for determining a cancer diagnosis and prognosis |
US20050282729A1 (en) * | 2002-05-28 | 2005-12-22 | Regents Of The Univeristy Of Minnesota | Crisp polypeptides as contraceptives and inhibitors of sperm capacitation |
WO2007092713A2 (en) * | 2006-02-02 | 2007-08-16 | Trustees Of The University Of Pennsylvania | Microfluidic system and method for analysis of gene expression in cell-containing samples and detection of disease |
US20100183562A1 (en) * | 2007-02-02 | 2010-07-22 | Istituto Nazionale Di Genetica Molecolare-Ingm | Sub -population of hematopoietic stem cells that express the crisp-1 protein |
CA2693546A1 (en) * | 2009-11-03 | 2011-05-03 | Universite Laval | Detection of human cysteine-rich secretory protein (crisp1) in semen and medical applications related thereto |
CN102914658A (en) * | 2012-10-24 | 2013-02-06 | 高维强 | Application of CRISP3 protein on diagnosis and treatment of prostate cancer |
Non-Patent Citations (3)
Title |
---|
HUI YE ET AL.: "Transcriptomic dissection of tongue squamous cell carcinoma", 《BMC GENOMICS》 * |
WEN-CHANG KO ET AL.: "Copy number changes of CRISP3 in oral squamous cell carcinoma", 《ONCOLOGY LETTERS》 * |
李庆伟等: "富含半胱氨酸分泌蛋白的结构及其离子通道方面作用的研究进展", 《辽宁师范大学学报(自然科学版)》 * |
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CN103267859B (en) | 2015-03-11 |
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Owner name: SHANGHAI TENTH PEOPLE'S HOSPITAL Free format text: FORMER OWNER: SUZHOU MAERTAI NEW MATERIALS CO., LTD. Effective date: 20150104 |
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Inventor after: Zhu Jinan Inventor after: Wan Sihui Inventor before: Zhu Jinan |
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Free format text: CORRECT: ADDRESS; FROM: 215400 SUZHOU, JIANGSU PROVINCE TO: 200072 PUTUO, SHANGHAI Free format text: CORRECT: INVENTOR; FROM: ZHU JINAN TO: ZHU JINAN WAN SIHUI |
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Effective date of registration: 20150104 Address after: 200072 No. 301, Yanchang Road, Shanghai Applicant after: Shanghai Tenth People's Hospital Address before: 215400 room 19, business center, 730 North Ring Road, pontoon Town, Suzhou City, Jiangsu, Taicang Applicant before: Suzhou Maertai New Material Co., Ltd. |
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Granted publication date: 20150311 Termination date: 20190522 |