CN103027757A - Micro electric field stimulation healing device for minitype dental implant - Google Patents

Micro electric field stimulation healing device for minitype dental implant Download PDF

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CN103027757A
CN103027757A CN2012105934174A CN201210593417A CN103027757A CN 103027757 A CN103027757 A CN 103027757A CN 2012105934174 A CN2012105934174 A CN 2012105934174A CN 201210593417 A CN201210593417 A CN 201210593417A CN 103027757 A CN103027757 A CN 103027757A
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healing
micro
constant
circuit module
implantation body
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CN103027757B (en
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李鸿波
高羽萱
刘洪臣
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Chinese PLA General Hospital
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Chinese PLA General Hospital
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Abstract

The invention discloses a micro electric field stimulation healing device for a minitype dental implant. The device is provided with a lower surface fitted with the top surface of the dental implant, and a stretching contact part, wherein a metal retention bolt penetrates through a circular through hole formed in the healing device, and fastened in the dental implant; dental resin is filled above the retention bolt, so that the retention bolt is separated from an oral environment; the device further comprises a micro and constant voltage circuit module or a micro and constant current circuit module; a negative electrode is arranged on the lower surface of the healing device, contacted with the dental implant, and on the external surface of a threaded rod of the retention bolt above the lower surface of the healing device; a positive electrode is arranged on the stretching contact part; and the negative electrode and the positive electrode are connected with an insulation protection layer. The healing device is small in size, can be mounted on the dental implant conveniently, is good in fixity, can be used for a long time, and can significantly shorten a healing period of the dental implant.

Description

Micro-type dental implantation body electric microfield stimulates device for healing
Technical field
The present invention relates to the dentistry implant device for healing, particularly micro-type dental implantation body electric microfield stimulates device for healing.
Background technology
The sixties in 20th century, Sweden scholar professor Brannemark finds, the formation of combining closely between the surface microstructure of Titanium and osseous tissue " bone integration ".The basis that bone integrated interface theory has been established modern oral implantology.The bone integrated interface is the basis of guaranteeing bone regeneration around implant osseous tissue energy stable for extended periods of time and bearing functional burdening.
The successful healing at interface and to keep stable also be the successful key factor of plantation between mucosa and the implantation body.Tooth implant penetrates mucous membrane tissue and is exposed to the oral cavity, need to set up a good connective tissue sealing, prevents that for implantation body provides oral cavity bacterium and toxin thereof from entering one barrier of interior environment.The mucous membrane tissue of bone regeneration around implant is similar to the periodontal gum tissue of nature, but compares with the natural teeth gingiva, this layer relatively avascular soft tissue defense mechanism a little less than.
Plantation reparation is the focus of present clinical oral and stomatology research, and the healing level that improves gingiva tissue and osseous tissue is facing of task.Mesenchymal stem cells MSCs migrate to implantation body-bone interface and deposit sclerotin, epidermis and periodontal tissue stem cell migrate to implantation body-gingiva interface and form implantation body and gingival epithelium between combination be the key that implantation body succeeds.
Be widely used aspect the growth of the healing that the method for galvanic stimulation is fractured in promotion, the treatment of wound, nerve.
The therapeutic equipments of the related bone healing of putting down in writing in the existing patent, the method for having used galvanic stimulation such as Chinese patent application CN201120200642.8, CN90100934.2, the disclosed therapeutic equipments of CN200610061732.7 promotes union of fracture.But these instruments all are to promote its wound healing by galvanism bone, have not yet to see the instrument that the method that adopts electric current, voltage to stimulate promotes the dentistry implant healing, and these instruments or with the host computer of heaviness, with capacitor plate, carry inconvenience, have limitation.
So far, not yet promote the report of dentistry implant healing small in the oral cavity relevant for electrical stimulation.
Summary of the invention
In order to address the above problem; the inventor has carried out with keen determination research; found that: by constant little electric current or micro voltage dentistry implant is carried out electricity irritation; can effectively promote the healing of implantation body; shorten healing time; particularly; adopt the negative electrode that coincide and contact with the dentistry implant upper surface; the metallic maintenance bolt that contacts with negative electrode simultaneously is fixed in negative electrode on the dentistry implant; in the part of stretching out the anode that contacts with other positions such as soft tissue etc. in the oral cavity is set; by negative electrode and anode respectively in dentistry implant and the oral cavity other positions electricity irritation is provided; the maintenance bolt is resin-sealed by dentistry; and by insulating protective layer and other position insulation of oral cavity, the gained device not only can be realized the quickly-healing of dentistry implant, and this device volume is small; install at dentistry implant; convenient disassembly; easy to use, cleaning is easy, thereby finishes the present invention.
The object of the present invention is to provide following aspect:
(1) a kind of micro-type dental implantation body electric microfield stimulates device for healing, it is characterized in that, this device has the lower surface that matches with the dentistry implant end face, and stretch out contact site (2), metallic maintenance bolt (1) passes the manhole (1a) of offering on this device for healing, is anchored in the dentistry implant filling dentistry resin (7) on the maintenance bolt, so that the isolation of maintenance bolt and oral environment, and be integral with this device for healing remainder; Insulating protective layer is arranged at the outer surface of this device for healing, so that electronic component and oral environment isolation;
This device for healing comprises:
Power supply,
Micro voltage constant voltage circuit module is used to electrode that constant voltage is provided,
Little electric current constant-current circuit module is used to electrode that constant electric current is provided,
Electrode comprises negative electrode (6) and anelectrode (5), and being used for derives and offer respectively other positions in dentistry implant and the human oral cavity with the curtage of little electric current constant-current circuit or the output of micro voltage constant voltage circuit,
Wherein, micro voltage constant voltage circuit module and little electric current constant-current circuit module the two not and deposit, select an existence, in other words, micro-type dental implantation body electric microfield stimulates device for healing or comprises micro voltage constant voltage circuit module or comprise little electric current constant-current circuit module;
Negative electrode (6) is arranged on the lower surface of this device for healing and dentistry implant joint; and the screw rod outer surface of device for healing lower surface top maintenance bolt (1); anelectrode (5) is arranged at and stretches out on the contact site, and negative electrode (6) is connected with insulating protective layer (3) respectively with anelectrode (5).
(2) stimulate device for healing according to the described micro-type dental in above-mentioned aspect implantation body electric microfield, it is characterized in that,
Described micro voltage constant voltage circuit module comprises supply module and constant voltage control module, and supply module provides stable power supply for micro voltage constant voltage circuit module, and the constant voltage control module is used for converting the power supply that supply module provides to constant voltage and outputs to electrode.
(3) stimulate device for healing according to the described micro-type dental in above-mentioned aspect implantation body electric microfield, it is characterized in that,
Described little electric current constant-current circuit module comprises supply module and constant-current control module, and supply module provides stable power supply for little electric current constant-current circuit module, and the power supply that constant-current control module is used for supply module is provided converts constant current output to electrode.
(4) stimulate device for healing according to the described micro-type dental in above-mentioned aspect implantation body electric microfield, it is characterized in that,
Dentistry resin (7) upper surface is identical with the upper level of device for healing remainder.
(5) stimulate device for healing according to the described micro-type dental in above-mentioned aspect implantation body electric microfield, it is characterized in that,
Insulating protective layer is made by porcelain, resin, plastics or other insulating polymeric materials.
(6) stimulate device for healing according to the described micro-type dental in above-mentioned aspect implantation body electric microfield, it is characterized in that,
Stretch out contact site and have the part of crossing out and vertical contact portion, surface-coated insulating protective layer, inside is power supply, micro voltage constant voltage circuit module or little electric current constant-current circuit module,
Cross out part and keep certain interval with gingiva, be convenient to local sanitation and hygiene.
(7) the micro-type dental implantation body electric microfield of stating according to above-mentioned aspect stimulates device for healing, it is characterized in that,
Anelectrode (5) is arranged at the bottom of contact site.
(8) the micro-type dental implantation body electric microfield according to above-mentioned aspect stimulates device for healing, it is characterized in that,
Anelectrode contacts with other soft tissues in gingiva or the oral cavity.
(9) the micro-type dental implantation body electric microfield according to above-mentioned aspect stimulates device for healing, it is characterized in that,
Negative electrode respectively with screw rod and the dentistry implant butt of maintenance bolt.
(10) the micro-type dental implantation body electric microfield according to above-mentioned aspect stimulates device for healing, it is characterized in that,
Micro voltage constant voltage circuit module provides the following voltage of 5V;
Little electric current constant-current circuit module provides the 10-200 μ electric current of A.
Stimulate the device for healing volume very small according to micro-type dental provided by the invention implantation body electric microfield, can be installed on easily on the dentistry implant, and patient's oral environment is not brought inconvenience, do not affect patient's orthobiosis, can provide electricity irritation for dentistry implant for a long time, so that the dentistry implant quickly-healing, and cleaning is suitable for life-time service easily.After patient's the dentistry implant healing, remove the dentistry resin of sealing, take off the maintenance bolt and whole device for healing can be removed, it is very convenient to dismantle.
Description of drawings
Fig. 1 illustrates the according to the preferred embodiment of the present invention schematic top plan view of micro-type dental implantation body electric microfield stimulation device for healing;
Fig. 2 illustrates the according to the preferred embodiment of the present invention cross-sectional view of micro-type dental implantation body electric microfield stimulation device for healing;
Fig. 3 illustrates the according to the preferred embodiment of the present invention cross-sectional view of micro-type dental implantation body electric microfield stimulation device for healing;
Fig. 4 illustrates the according to the preferred embodiment of the present invention mounting structure sketch map of micro-type dental implantation body electric microfield stimulation device for healing;
Fig. 5 illustrates the according to the preferred embodiment of the present invention structural representation of the supply module of micro-type dental implantation body electric microfield stimulation device for healing;
Fig. 6 illustrates the according to the preferred embodiment of the present invention structural representation of the constant voltage control module of micro-type dental implantation body electric microfield stimulation device for healing;
Fig. 7 illustrates the according to the preferred embodiment of the present invention circuit theory diagrams of little electric current constant voltage control module of micro-type dental implantation body electric microfield stimulation device for healing.
The drawing reference numeral explanation:
1-maintenance bolt
The 1a-through hole
2-stretches out contact site
The 3-insulating protective layer
The 4-minicell
The 5-anelectrode
The 6-negative electrode
7-dentistry resin
The 8-dentistry implant
21-unidirectional current transducer
22-unidirectional current transducer
The 23-controller
The 23a-A-D converter
The 23b-digital analog converter
24-operational amplifier group
The 24a-operational amplifier
The 24b-operational amplifier
24c-resistance
The specific embodiment
Below by the present invention is described in detail, characteristics of the present invention and advantage will become more clear, clear and definite along with these explanations.
Here special-purpose word " exemplary " means " as example, embodiment or illustrative ".Here needn't be interpreted as being better than or being better than other embodiment as " exemplary " illustrated any embodiment.Although accompanying drawing unless otherwise indicated, needn't be drawn in proportion in the various aspects of embodiment shown in the drawings.
The inventor finds through research, after tissue damaged hinders namely at damaged tissue and the stable Endogenous Electrical Fields (about 100-200mv) of one of formation between the damaged tissue, this electric field persistent period is grown (a few days is to several weeks), be distributed in around the damaged tissue in several millimeters the spatial dimension, nearer apart from damaged tissue, electric field is more obvious; The new bone apposition of generation that always can be constant at the nagative potential place, and the positive potential place often produces bone resorption, this discloses displaceable electric charge to the significance of osteogenesis process.In addition, the research about skin progenitor cell shows that also under the effect of electric microfield, epidermal stem cells is to the movable cathode of electric field.Therefore, the inventor thinks: tooth implant is applied the migration that external electric field can the Effective Raise stem cell, promote the healing of Peri-implant tissues and is combined with implantation body, improve the healing of implantation body, the raising success rate.
Disclosed by the invention is that a kind of micro-type dental implantation body electric microfield of dentistry implant healing that can promote stimulates device for healing, uses this device to be beneficial to the healing of tooth implant, improves the success rate that clinical plantation is repaired.
In according to a preferred embodiment of the present invention, as shown in Fig. 1-4, provide a kind of micro-type dental implantation body electric microfield to stimulate device for healing, this device has the lower surface that matches with the dentistry implant end face, and stretching out contact site 2, metallic maintenance bolt 1 passes the manhole 1a that offers on this device for healing, is anchored in the dentistry implant, filling dentistry resin 7 on the maintenance bolt is so that dentistry resin 7 is integral with this device for healing remainder;
This device for healing comprises:
Power supply,
Micro voltage constant voltage circuit module is used to electrode that constant voltage is provided,
Little electric current constant-current circuit module is used to electrode that constant electric current is provided,
Electrode comprises negative electrode 6 and anelectrode 5, and being used for derives and offer respectively other positions in dentistry implant and the human oral cavity with the curtage of little electric current constant-current circuit or the output of micro voltage constant voltage circuit,
Insulating protective layer 3 is arranged at the outer surface of this device for healing, so that electronic component and oral environment isolation;
Wherein, micro voltage constant voltage circuit module and little electric current constant-current circuit module the two not and deposit, select an existence, in other words, micro-type dental implantation body electric microfield stimulates device for healing or comprises micro voltage constant voltage circuit module or comprise little electric current constant-current circuit module;
Negative electrode 6 is arranged on the lower surface of this device for healing and dentistry implant joint; and the screw rod outer surface of device for healing lower surface top maintenance bolt 1; anelectrode 5 is arranged at and stretches out on the contact site, and negative electrode 6 is connected with insulating protective layer 3 respectively with anelectrode 5.
Wherein, in order to install and fix with dentistry implant easily, match according to micro-type dental implantation body's lower surface provided by the invention and dentistry implant upper surface, seamless between the two after installing like this, can prevent that the foreign body intrusion from causing being difficult between dentistry implant and surrounding tissue healing therebetween.
In preferred implementation according to the present invention, micro-type dental implantation body electric microfield stimulates device for healing to comprise barrel-shaped main part and stretches out contact site 2, shown in Fig. 1,2 and 3.Wherein, main part is used for installing with dentistry implant, fixing, and holds circuit module such as micro voltage constant voltage circuit module or little electric current constant-current circuit module; Stretching out contact site is used for contacting with other positions such as soft tissue in the oral cavity.
Stimulate in the device for healing at electric microfield according to the present invention, by maintenance bolt 1 this device for healing is fixed to the dentistry implant upper surface, so that this device for healing can stably be fastened on the dentistry implant surface in curing the dentistry implant agglutination, avoid device for healing displacement in therapeutic process.
Use metallic maintenance bolt as the maintenance bolt, be not particularly limited for metal, but preferably use titanium or titanium alloys maintenance bolt, to improve biocompatibility.
The maintenance bolt is except the effect of playing fixing device for healing, also play the effect of conduction, because the maintenance bolt all contacts with negative electrode (negative electrode) with dentistry implant, the signal of telecommunication that can further negative electrode be exported imports in the dentistry implant, particularly when negative electrode and dentistry implant loose contact, as shown in Figure 4.
In the present invention, the dentistry resin prevents in the oral cavity that the material such as saliva corrodes the maintenance bolt.
In preferred implementation according to the present invention, dentistry resin 7 upper surfaces are identical with the upper level of device for healing remainder, thereby prevent patient oral cavity injury.
Stimulate in the device for healing at electric microfield of the present invention; insulating protective layer 3 can be made by porcelain, resin, plastics or other insulating polymeric materials; be arranged at the device for healing surface, protection and isolated circuit module avoid the interference of saliva, soft tissue etc. in the oral cavity.
Stimulate in the preferred implementation of device for healing at electric microfield according to the present invention, stretch out contact site and have the part of crossing out and vertical contact portion, as shown in Fig. 2,3 and 4.Wherein, cross out part so that micro-type dental implantation body electric microfield stimulates between the anode of device for healing and implantation body and keep certain gap, this gap can be so that scrub or be convenient to implantation body's cleaning line by the gap during cleaning and pass through, so that clean.
Especially, anelectrode 5 is arranged at the bottom of contact site, so that anelectrode 5 easily contacts with intraoral soft tissue etc.
In the present invention, as power supply, use minicell, such as button cell etc.The minicell volume is little, saves the space, and is easy to use.Minicell can also can be micro battery for miniature galvanic cell, and miniature galvanic cell can be changed before each treatment, and micro battery can charge after each the application, preferred miniature galvanic cell, and disposable use is conducive to health.
Be not particularly limited for battery variety, can use common power supply, such as smee cell, lithium battery etc.
Stimulate in the preferred implementation of device for healing at electric microfield according to the present invention, micro voltage constant voltage circuit module provides the following voltage of 5V; Little electric current constant-current circuit module provides the following electric current of 500 μ A.Further preferably, micro voltage constant voltage circuit module provides 1-3V voltage; Little electric current constant-current circuit module provides 10-200 μ A electric current.
Stimulate in the device for healing at electric microfield according to the present invention, do not have specific (special) requirements for micro voltage constant voltage circuit module and little electric current constant-current circuit module, can use common constant voltage circuit module and constant-current circuit module.
In one embodiment, described micro voltage constant voltage circuit module comprises supply module and constant voltage control module, supply module provides stable power supply for micro voltage constant voltage circuit module, and the constant voltage control module is used for converting the power supply that supply module provides to constant voltage and outputs to electrode.
In one embodiment, described little electric current constant-current circuit module comprises supply module and constant-current control module, supply module provides stable power supply for little electric current constant-current circuit module, and the power supply that constant-current control module is used for supply module is provided converts constant current output to electrode.
Below only the constant voltage control module is described further.
Shown in Fig. 5,6 and 7, in one embodiment, the constant voltage control module comprises:
Controller, the signal by accepting operational amplifier group output and to the mode control algorithm amplifier group of operational amplifier group input signal, so that the operational amplifier group can be exported constant voltage circuit,
The operational amplifier group is input to electrode for generation of constant voltage circuit and with constant voltage.
Wherein, unidirectional current transducer 21 becomes fixed voltage to be input to the operational amplifier group voltage transitions of minicell 4,
Unidirectional current transducer 22 becomes fixed voltage to be input to controller the voltage transitions of minicell 4.
Wherein, the annexation of supply module such as Fig. 5, minicell 4 link to each other with unidirectional current transducer 22 with unidirectional current transducer 21 respectively, and the outfan of unidirectional current transducer 21 and unidirectional current transducer 22 is the outfan of supply module.
Wherein, annexation such as Fig. 5 of supply module and constant voltage control module, unidirectional current transducer 21 links to each other with operational amplifier group 24, and unidirectional current transducer 22 links to each other with controller 23.
Wherein, the operational amplifier group comprises:
Operational amplifier 24a becomes the signal (Vin) of controller input into the voltage signal of equal proportion and with voltage signal input resistance 24c and operational amplifier 24b,
Operational amplifier 24b receives the signal of self-resistance and operational amplifier 24a, and output signal sends into operational amplifier 24a and controller, realizes constant current output by closed loop feedback,
Wherein, operational amplifier 24a and operational amplifier 24b all receive the voltage from unidirectional current transducer 21.
In the constant voltage control module, controller is by to operational amplifier group input signal and accept the mode control algorithm amplifier group of operational amplifier group signal, so that the operational amplifier group can be exported the constant voltage signal of telecommunication.
Wherein, controller comprises:
Digital analog converter 23b is worth proportional control voltage for output with the setting constant voltage and sends into operational amplifier 24a as input signal (Vin),
Analog-digital converter 23a is for the signal that receives operational amplifier 24b.
Wherein, the annexation of controller and operational amplifier group as shown in Figure 6, digital analog converter 23b is to operational amplifier 24a input signal, operational amplifier 24b is to analog-digital converter 23a input signal.
Clinical trial
For the 10 routine clinical patients of accepting dentistry implant, installation stimulates device for healing according to micro-type dental provided by the invention implantation body electric microfield, observe the dentistry implant healing cycle and be 1-2 month, and the patient that micro-type dental implantation body electric microfield stimulates device for healing is not installed, the clinical observation healing cycle is 3-4 month.
Show thus, stimulate device for healing can effectively promote the dentistry implant quickly-healing according to micro-type dental provided by the invention implantation body electric microfield, shorten healing cycle.
Abovely in conjunction with the specific embodiment and exemplary example the present invention is had been described in detail, but these explanations can not be interpreted as limitation of the present invention.It will be appreciated by those skilled in the art that in the situation that does not depart from spirit and scope of the invention can carry out multiple replacement of equal value, modify or improve technical solution of the present invention and embodiment thereof, these all fall within the scope of the present invention.Protection scope of the present invention is as the criterion with claims.

Claims (10)

1. micro-type dental implantation body electric microfield stimulates device for healing, it is characterized in that, this device has the lower surface that matches with dentistry implant (8) end face, and stretch out contact site (2), metallic maintenance bolt (1) passes the manhole (1a) of offering on this device for healing, is anchored in the dentistry implant filling dentistry resin (7) on the maintenance bolt, so that the isolation of maintenance bolt and oral environment, and be integral with this device for healing remainder; Insulating protective layer is arranged at the outer surface of this device for healing, so that electronic component and oral environment isolation;
This device for healing comprises:
Power supply,
Micro voltage constant voltage circuit module is used to electrode that constant voltage is provided,
Little electric current constant-current circuit module is used to electrode that constant electric current is provided,
Electrode comprises negative electrode (6) and anelectrode (5), and being used for derives and offer respectively other positions in dentistry implant and the human oral cavity with the curtage of little electric current constant-current circuit or the output of micro voltage constant voltage circuit,
Wherein, micro voltage constant voltage circuit module and little electric current constant-current circuit module the two not and deposit, select an existence, in other words, micro-type dental implantation body electric microfield stimulates device for healing or comprises micro voltage constant voltage circuit module or comprise little electric current constant-current circuit module;
Negative electrode (6) is arranged on the lower surface of this device for healing and dentistry implant joint; and the screw rod outer surface of device for healing lower surface top maintenance bolt (1); anelectrode (5) is arranged at and stretches out on the contact site, and negative electrode (6) is connected with insulating protective layer (3) respectively with anelectrode (5).
2. micro-type dental according to claim 1 implantation body electric microfield stimulates device for healing, it is characterized in that,
Described micro voltage constant voltage circuit module comprises supply module and constant voltage control module, and supply module provides stable power supply for micro voltage constant voltage circuit module, and the constant voltage control module is used for converting the power supply that supply module provides to constant voltage and outputs to electrode.
3. micro-type dental according to claim 1 implantation body electric microfield stimulates device for healing, it is characterized in that,
Described little electric current constant-current circuit module comprises supply module and constant-current control module, and supply module provides stable power supply for little electric current constant-current circuit module, and the power supply that constant-current control module is used for supply module is provided converts constant current output to electrode.
4. micro-type dental according to claim 1 implantation body electric microfield stimulates device for healing, it is characterized in that,
Dentistry resin (7) upper surface is identical with the upper level of device for healing remainder.
5. micro-type dental according to claim 1 implantation body electric microfield stimulates device for healing, it is characterized in that,
Insulating protective layer is made by porcelain, resin, plastics or other insulating polymeric materials.
6. micro-type dental according to claim 1 implantation body electric microfield stimulates device for healing, it is characterized in that,
Stretch out contact site (2) and have the part of crossing out and vertical contact portion, surface-coated insulating protective layer, inside is power supply, micro voltage constant voltage circuit module or little electric current constant-current circuit module,
Cross out part and keep certain interval with gingiva, be convenient to local sanitation and hygiene.
7. micro-type dental according to claim 6 implantation body electric microfield stimulates device for healing, it is characterized in that,
Anelectrode (5) is arranged at the bottom of contact site.
According to claim 1 or 7 described micro-type dental implantation body electric microfields stimulate device for healing, it is characterized in that,
Anelectrode contacts with other soft tissues in gingiva or the oral cavity.
According to claim 1 or 7 described micro-type dental implantation body electric microfields stimulate device for healing, it is characterized in that,
Negative electrode respectively with screw rod and the dentistry implant butt of maintenance bolt.
10. micro-type dental according to claim 1 implantation body electric microfield stimulates device for healing, it is characterized in that,
Micro voltage constant voltage circuit module provides the following voltage of 5V;
Little electric current constant-current circuit module provides 10-200 μ A electric current.
CN201210593417.4A 2012-12-31 2012-12-31 Micro electric field stimulation healing device for minitype dental implant Active CN103027757B (en)

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CN110680527A (en) * 2019-09-24 2020-01-14 西安交通大学 Implant system, microelectrode module and dielectrophoresis method
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WO2020161704A1 (en) 2019-02-05 2020-08-13 Rafael Sirkis Novel system and methods for speeding up the healing of dental implants

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