CN102753232A - Substance discharge device - Google Patents

Abstract

A substance discharge device (100) is provided with an oscillation unit (120) which oscillates an amplitude-modulated ultrasonic wave group obtained by modulating the amplitudes of ultrasonic waves to the surface of a discharger (200) of an excretory substance, and a control unit (130) which controls the amplitudes of the ultrasonic waves of the amplitude-modulated ultrasonic wave group oscillated by the oscillation unit (120) on the basis of the drift speed of the excretory substance with respect to the discharger (200). Consequently, the excretory substance is discharged to the outside of the discharger from the surface of the discharger such as a human body using ultrasonic oscillation, thereby achieving efficient discharge corresponding to the excretory substance.

Description

Material discharger

Technical field

The surface that the present invention relates to be discharged from from human body etc. body is discharged to the material discharger that this is discharged from the outside of body with ejected matter.

Background technology

At present, as cosmetic surgery, having proposed provides hyperacoustic vibration to reach all technology of various purposes to the surface of human body etc.

For example, in patent documentation 1, disclose to the skin exposure ultrasound wave, carried out the cosmetic surgery method that cleaning and cutin in the pore are removed simultaneously.

And, the cosmetic surgery method that removes the chaeta of this irradiated site to the skin exposure ultrasound wave is disclosed in patent documentation 2.

The prior art document

Patent documentation

Patent documentation 1: TOHKEMY 2007-159950 communique

Patent documentation 2: TOHKEMY 2002-527162 communique

Summary of the invention

The problem that invention will solve

In the so-called skin nursing in beauty treatment fields,, use that the light that uses equipment such as laser instrument is treated and chemotherapy etc. for example as the cosmetic surgery that waits to superfluous sebum (acne).

Yet present situation is that also untapped sening as an envoy to carried out the ultrasonic equipment of the treatment etc. of acne with ultrasound wave.

Equally, be discharged to external surgical operation at the substance in vivo that carries out pus, blood stasis, transudate etc., promptly under the situation of so-called drainage, the yet untapped ultrasonic equipment that goes out for this reason to use.

The purpose of this invention is to provide a kind of material discharger, it uses ultrasonic vibration from the surface that human body etc. is discharged from body ejected matter to be discharged to this outside that is discharged from body, to realize the effective discharge corresponding with this ejected matter.

Be used to solve the means of problem

Material discharger of the present invention is discharged to the outside from the surface that is discharged from body with ejected matter; It has: supersonic oscillations portion, the Modulation and Amplitude Modulation ultrasound wave group it is modulated each hyperacoustic amplitude the said surface oscillation that is discharged from body with mode decrescence after; And control part, it with respect to the said drift velocity that is discharged from body, controls each hyperacoustic amplitude of said Modulation and Amplitude Modulation ultrasound wave group according to said ejected matter.

The invention effect

According to the present invention, the surface that can use ultrasonic vibration to be discharged from body from human body etc. is discharged to ejected matter this outside that is discharged from body, realizes the effective discharge corresponding with this ejected matter.

Description of drawings

Fig. 1 is the block diagram of schematic configuration that the material discharger of embodiment of the present invention is shown.

Fig. 2 is the axonometric chart of structure example of supersonic oscillations portion that schematically shows the material discharger of embodiment of the present invention.

Fig. 3 illustrates Modulation and Amplitude Modulation ultrasound wave group of the skin that is discharged from body being vibrated from supersonic oscillations portion and the performance plot that is in harmonious proportion probability function thereof.

The equivalent circuit diagram of the mechanical model when Fig. 4 is the positive amplitude of sin deformation of wave.

Fig. 5 is the sketch map that is illustrated in the state that is provided with of the sample that uses in the experiment 1.

Fig. 6 illustrates the figure as the photo of each filter paper after No. 102 diffusions of redness of ejected matter according to embodiment and comparative example 1,2 in experiment 2.

Fig. 7 is the performance plot of relation that the concentration of experimental period and red No. 102 is shown to Sample A, B, C in experiment 2.

Fig. 8 A is the performance plot that the difference of experiment value and approximate data is shown to comparative example 1.

Fig. 8 B is the performance plot that the difference of experiment value and approximate data is shown to comparative example 2.

Fig. 8 C is the performance plot that the difference of experiment value and approximate data is shown to embodiment.

Fig. 9 is the table that flow velocity J is shown to embodiment and comparative example 1,2.

Figure 10 is the performance plot in the Modulation and Amplitude Modulation ultrasound wave group of from the vibration section skin that is discharged from body being vibrated shown in the modified example of this embodiment.

The specific embodiment

Fig. 1 is the block diagram of schematic configuration that the material discharger 100 of embodiment of the present invention is shown.

As shown in Figure 1, material discharger 100 constitutes to have: vibration section 120, control part 130, information input unit 140 and drift velocity value storage part 150.

On the surface (skin 201) that is discharged from body (in this embodiment for example human body) 200, be equipped with ejected matter absorber 110.Ejected matter absorber 110 absorbs the ejected matter of discharging from this surface, for example can select filter paper etc.

Vibration section 120 constitutes has the for example piezoelectric element (not shown) of PZT etc., is discharged from each hyperacoustic amplitude of surface oscillation of body 200 Modulation and Amplitude Modulation ultrasound wave group after modulated across 110 pairs of ejected matter absorbers.Through the vibration of the Modulation and Amplitude Modulation ultrasound wave group of being undertaken, make the ejected matters that are discharged from the body 200 discharge and absorb by ejected matter absorber 110 from skin 201 by this vibration section 120.

In vibration section 120, as shown in Figure 2, can ring-type oscillator 121 be set with this abutment portion that is discharged from the surface of body 200.The butt position with being discharged from body 200 of this ring-type oscillator 121 is cyclic tabular surface.Through ring-type oscillator 121 is set, via ejected matter absorber 110 when being discharged from the surperficial butt of body 200, produce partial stress gradient in the part of ring-type oscillator 121.In this case; Becoming core (by the core of ring-type oscillator 121 area surrounded) stress reduction vibration section 120 and the non-abutting part surface that is discharged from body 200; Drain position at this surperficial ejected matter is localized, and discharging efficient increases.

The various information of information that information input unit 140 will for example comprise the output of the kinds of information that becomes the ejected matter of discharging object and this ejected matter are input to the CPU133 of control part 130.

The a plurality of drift velocity values of drift velocity value storage part 150 storage, in drift velocity value storage part 150 for example by the various types of drift velocity value that stores of ejected matter.

Control part 130 is according to the drift velocity to the ejected matter that is discharged from body 200, the amplitude each ultrasound wave of the Modulation and Amplitude Modulation ultrasound wave group that control is vibrated from vibration section 120.This control part 130 constitutes to have: vibration ultrasound examination portion 131, ultrasonic amplitude extraction portion 132, CPU133, ultrasonic amplitude adjustment part 134, phase detection portion 135, resonant frequency adjustment part 136, alternating voltage sending part 137, voltage-adjusting amplifier 138 and power amplification portion 139.

Each ultrasound wave that the Modulation and Amplitude Modulation ultrasound wave group of 120 vibrations from the vibration section detects in vibration ultrasound examination portion 131 is as magnitude of voltage.Ultrasonic amplitude extraction portion 132 extracts its amplitude as magnitude of voltage according to by vibration ultrasound examination portion 131 detected each ultrasound wave.

CPU133 unifies control to the action in the material discharger 100.For example; CPU133 extracts corresponding drift velocity value according to the kind of the ejected matter of importing from information input unit 140 from drift velocity value storage part 150; According to this drift velocity value that extracts, the control signal that will be used to control from the vibration section amplitude of the 120 Modulation and Amplitude Modulation ultrasound wave groups of vibrating sends to ultrasonic amplitude adjustment part 134.And; For example; The information that CPU133 related to according to the output from the ejected matter of information input unit 140 input; Decision is 120 each hyperacoustic quantity of vibrating as a Modulation and Amplitude Modulation ultrasound wave group from the vibration section, will send to ultrasonic amplitude adjustment part 134 based on the control signal of this decision.

Specifically, CPU133 control signal and the control signal of each hyperacoustic quantity of vibrating as Modulation and Amplitude Modulation ultrasound wave group that will be used to control the amplitude of Modulation and Amplitude Modulation ultrasound wave group exported as the serrated signal voltage of negative gradient shown in Figure 1.Here, each sawtooth is the dull linear waveform that reduces.The drift velocity value that the absolute value of the gradient (gradient) of the dullness minimizing portion of sawtooth is equivalent to extract, and, according to each hyperacoustic quantity that turn-on time, control was vibrated as 1 Modulation and Amplitude Modulation ultrasound wave group of sawtooth.

The magnitude of voltage of each hyperacoustic amplitude that ultrasonic amplitude adjustment part 134 will be extracted by ultrasonic amplitude extraction portion 132 and from the serrated signal voltage of CPU133 as input; The amplitude that is adjusted in each ultrasound wave that makes the Modulation and Amplitude Modulation ultrasound wave group that vibration section 120 vibrates is below the said drift velocity; And output control voltage, each hyperacoustic quantity that this control voltage adjustment is vibrated as this Modulation and Amplitude Modulation ultrasound wave group.

Phase detection portion 135 is detected by each hyperacoustic waveform of vibration ultrasound examination portion 131 detected Modulation and Amplitude Modulation ultrasound wave groups with from the phase place of the waveform of the alternating voltage of alternating voltage sending part 137 outputs.Resonant frequency adjustment part 136 is controlled from the phase place of the alternating voltage of alternating voltage sending part 137 outputs according to by phase detection portion 135 detected phase places, is adjusted to make vibration section 120 be in resonance state.Promptly; This phase detection portion 135 constitutes " configuration part " of the present invention with resonant frequency adjustment part 136; Promptly; According to each ultrasound wave by vibration ultrasound examination portion 131 detected Modulation and Amplitude Modulation ultrasound wave groups, control each hyperacoustic phase contrast of this Modulation and Amplitude Modulation ultrasound wave group, vibration section 120 is set at resonance state.

Alternating voltage sending part 137 sends alternating voltage (for example, sine voltage).Voltage-adjusting amplifier 138 is controlled etc. as follows, promptly according to the control voltage of 134 outputs from the ultrasonic amplitude adjustment part alternating voltage that sends from alternating voltage sending part 137 is modulated.139 pairs in the power amplification portion alternating voltage after by voltage-adjusting amplifier 138 modulation carries out power amplification and outputs to vibration section 120.

In vibration section 120, the alternating voltage of importing from power amplification portion 139 imposes on above-mentioned piezoelectric element (not shown), produces the distortion based on this alternating voltage at piezoelectric element.Thus, the Modulation and Amplitude Modulation ultrasound wave group after from vibration section 120 vibration each hyperacoustic amplitude being modulated.

Then, explain and considered that ejected matter (followingly is set at V with this drift velocity with respect to the drift velocity that is discharged from body 200 _d) material discharge method of the present invention.

Fig. 3 illustrates from the vibration section Modulation and Amplitude Modulation ultrasound wave group that 120 pairs of skins 201 that are discharged from body 200 vibrate and the performance plot that is in harmonious proportion probability function thereof.

At first, the Modulation and Amplitude Modulation ultrasound wave group shown in the key diagram 3 (a).

Shown in Fig. 3 (a), a plurality of ultrasound wave after in 1 Modulation and Amplitude Modulation ultrasound wave group that the surface (skin 201) that 120 pairs of vibration sections is discharged from body 200 vibrates, having amplitude modulated respectively.Hyperacoustic quantity of vibrating as this 1 Modulation and Amplitude Modulation ultrasound wave group for example is that the information according to the output of the ejected matter of importing (setting) from information input unit 140 decides in control part 130 (CPU133).

And, shown in Fig. 3 (a), these each hyperacoustic amplitudes of control part 130 control, make the elapsed time (t) of amplitude with respect to the time in each ultrasound wave of this Modulation and Amplitude Modulation ultrasound wave group from the starting of oscillation of 1 Modulation and Amplitude Modulation ultrasound wave group gradient-V _eThe absolute value V of (this gradient also can be described as the speed of each hyperacoustic amplitude with respect to elapsed time (t)) _eBe drift velocity V _dBelow.Here, in Fig. 3 (a), make the gradient (gradient) of the line segment of the single-point line that connects each hyperacoustic amplitude be-V _e

And; Shown in Fig. 3 (a); Control part 130 is controlled as follows: to each ultrasound wave of 1 Modulation and Amplitude Modulation ultrasound wave group; Initial ultrasound wave during from the starting of oscillation of this Modulation and Amplitude Modulation ultrasound wave group till the last ultrasound wave according to the hyperacoustic quantity that will vibrate of the information decision of the output of ejected matter, makes that amplitude is dull to be reduced.That is, make each hyperacoustic amplitude with gradient-V _eThe dull minimizing.

Here, the amplitude of the initial ultrasound wave during according to the starting of oscillation of Modulation and Amplitude Modulation ultrasound wave group (amplitude is maximum ultrasound wave in each ultrasound wave of Modulation and Amplitude Modulation ultrasound wave group), decision is discharged from the hyperacoustic discharge degree of depth in the body 200.

To as the vibration section of oscillator 120 be discharged from body 200, young's modulus is set at E ₁, E ₂, will be out of shape amplitude setting is ε ₁, ε ₂, shown in following formula (1), the stress that produces according to the hyperacoustic vibration of vibration section 120 equals to be discharged from the resistance of body 200.

ε ₁E ₁＝ε ₂E ₂ …（1）

Therefore, as the distortion amplitude ε that is discharged from body 200 that discharges the degree of depth ₂Shown in following formula (2).

${\mathrm{\ϵ}}_2={\mathrm{\ϵ}}_1\frac{E_1}{E_2}\·\·\·\left(2\right)$

Thus, the initial hyperacoustic amplitude the during starting of oscillation of Modulation and Amplitude Modulation ultrasound wave group is the value of discharge degree of depth decision as required.

And; Shown in Fig. 3 (a); Control part 130 is after said last hyperacoustic control of having carried out 1 Modulation and Amplitude Modulation ultrasound wave group; Execution from the vibration section 120 carry out the vibration of next Modulation and Amplitude Modulation ultrasound wave group control, be controlled to the zigzag fashion shown in the single-point line that is shaped as Fig. 3 (a) that makes the Modulation and Amplitude Modulation ultrasound wave group of vibrating.

Then, the General Principle of the mediation probability function shown in the key diagram 3 (b).

Concentration is set at C, then since external force F and (solid) causes in uniform system flow velocity J shown in following formula (3) and formula (4).

$J=-D\▿C-D\frac{\mathrm{CF}}{\mathrm{KT}}\·\·\·\left(3\right)$

$=J_C+J_F\·\·\·\left(4\right)$

D: diffusion coefficient K: Boltzmann constant

T: absolute temperature J _C: the flow that causes by Concentraton gradient

J _F: the flow that causes by vibration stress

And ejected matter is with respect to the drift velocity V that is discharged from body 200 _dShown in following formula (5).

$V_d=\frac{D}{\mathrm{KT}}F\·\·\·\left(5\right)$

Here, shown in the formula described as follows (6), will be set at effectively that (discharge of the ejected matter that is only caused by Concentraton gradient is invalid by the discharge that vibration stress causes.), the amplitude of establishing vibration stress is A, then the amplitude A of vibration stress is shown in following formula (7).

J _C<<J _F …（6）

A=Eεcosω …（7）

Here, the E of formula (7) representes young's modulus, and ε representes to be out of shape amplitude.Then, the speed of establishing distortion amplitude ε is v, and the ripple that then is out of shape amplitude ε shakes the life period Δ t of face x and x+ Δ x shown in following formula (8) and formula (9).

$\mathrm{\&Delta;t}=2\left|\frac{\mathrm{\&Delta;x}}{v}\right|=\left|\frac{2\mathrm{\&Delta;x}}{\mathrm{\&omega;\&epsiv;}\sin \mathrm{\&omega;t}}\right|\&CenterDot;\&CenterDot;\&CenterDot;\left(8\right)$

$=\frac{2\mathrm{\&Delta;x}}{\mathrm{\&omega;}\sqrt{{\mathrm{\&epsiv;}}^2-x^2}}\&CenterDot;\&CenterDot;\&CenterDot;\left(9\right)$

Then, establishing the vibration period is τ, and what the ripple that then is out of shape amplitude ε shook face x exists probability P (x) shown in following formula (10).

$P\left(x\right)=\frac{2\mathrm{\&Delta;x}}{\mathrm{\&tau;\&omega;}\sqrt{{\mathrm{\&epsiv;}}^2-x^2}}\&CenterDot;\&CenterDot;\&CenterDot;\left(10\right)$

The probability P (x) that exists by this formula (10) expression is equivalent to the characteristic of the mediation probability function shown in Fig. 3 (b).

On the other hand, the jump frequency ω of diffusate _jDrift velocity V is provided _dWhen the external force frequencies omega _FWhen being the condition shown in the following formula (11), can not follow the tracks of external force, external pressure amplitude P (x) _MAXPoint works as the drift velocity force position.

ω _j<<ω _F …（11）

Consider to use PZT as the piezoelectric element of vibration section 120, with the situation of this PZT as the driving vibration source of the discharge of ejected matter.The acoustic impedance of PZT is about 34.8 * 10 ⁶Kg/m ²S, and the acoustic impedance of muscle is about 1.5 * 10 ⁶Kg/m ²S, the acoustic impedance of muscle are about 1/20th sizes of the acoustic impedance of PZT.

And the acoustical vibration attenuation quotient of human body when ultrasonic frequency vibratory 80kHz, be about 0.15/cm, thereby human body is regarded as mitigation system through experiment.On the other hand, the vibration amplitude that provides to human body (being discharged from body 200) of the piezoelectric element of vibration section 120 is only limited to the positive side of the amplitude pressure function of sine wave (sin ripple).That is, only the positive side amplitude of sin ripple imposes on human body (being discharged from body 200) as impulsive force.Fig. 4 illustrates the equivalent circuit diagram of this mechanical model.

The positive amplitude A of sin deformation of wave (t) shown in Figure 4 is shown in following formula (12).

A(t)=|εsinωt|+εsinωt …（12）

This formula is carried out fourier progression expanding method, then be out of shape positive amplitude A (t) shown in following formula (13).

$A\left(t\right)=\frac{{\mathrm{\&epsiv;}}_0}{2}+\underset{n=1}{\overset{\&infin;}{\mathrm{\&Sigma;}}}{\mathrm{\&epsiv;}}_n\cos 2\mathrm{n\&omega;t}\&CenterDot;\&CenterDot;\&CenterDot;\left(13\right)$

Here, the ε of formula (13) ₀Shown in following formula (14), and, the ε of formula (13) _nShown in following formula (15),

${\mathrm{\&epsiv;}}_0=\frac{4\mathrm{\&epsiv;}}{\mathrm{\&pi;}}\&CenterDot;\&CenterDot;\&CenterDot;\left(14\right)$

${\mathrm{\&epsiv;}}_n=\frac{4\mathrm{\&epsiv;}}{\mathrm{\&pi;}(1-4n^2)}\&CenterDot;\&CenterDot;\&CenterDot;\left(15\right)$

As the amplitude ε shown in the formula (15) _nWhen being imported into mitigation system shown in Figure 4, becoming and relax the long-pending of function, ε _{N (out)}Shown in following formula (16).

${\mathrm{\&epsiv;}}_{n\left(\mathrm{out}\right)}=\frac{1}{1+{\left(\mathrm{\&omega;\&tau;}\right)}^2}\frac{4\mathrm{\&epsiv;}}{\mathrm{\&pi;}(1-4n^2)}\&CenterDot;\&CenterDot;\&CenterDot;\left(16\right)$

Formula (16) expression, as vibrational term, driving frequency is low more to drift velocity V _dEffect effective more.Here, formula (14) expression does not rely on the static pressure amplitude of ultrasound wave driving frequency ω.Then, Modulation and Amplitude Modulation ultrasound wave group shown in Fig. 3 (a) is such, and when applying Modulation and Amplitude Modulation when becoming zigzag fashion, formula (14) is shown in following formula (17).

${\mathrm{\&epsiv;}}_0=\frac{4\mathrm{\&epsiv;}}{\mathrm{\&pi;}}{V}_{e}t\&CenterDot;\&CenterDot;\&CenterDot;\left(17\right)$

Here, as stated ,-V _eThe speed in the elapsed time (t) of each hyperacoustic amplitude of representing 1 Modulation and Amplitude Modulation ultrasound wave group with respect to the time from the starting of oscillation of this Modulation and Amplitude Modulation ultrasound wave group; It is the gradient (gradient) of the zigzag fashion shown in the single-point line of Fig. 3 (a); As stated, the discharge condition of ejected matter must satisfy following formula (18).

V _e≤V _d …（18）

If being discharged from the diffusion activation energy of the ejected matter in the body 200 is U, the diffusion coefficient of establishing ejected matter is D.Diffusion coefficient D changes diffusion activation energy U, and the mobile probability when (distance, delta x under the external force) moves in abutting connection with the place with court in being discharged from body 200 is directly proportional.

And the power of establishing distance, delta x under every external force is F, then reduces ability Δ U, diffusion coefficient D _FShown in formula (19), (20).

ΔU=ΔxΔF …（19）

$D_F\&Proportional;{\mathrm{<figure-callout\; id="0"\; label="v"\; filenames="HDA00002005692900071.png,HDA00002005692900082.png"\; state="\{\{state\}\}">v</figure-callout>}}_0\exp (-\frac{U-\mathrm{\&Delta;x\&Delta;F}}{K_T})\&CenterDot;\&CenterDot;\&CenterDot;\left(20\right)$

Therefore, along the diffusion coefficient D of the solute concentration C of bar-shaped sample _FBecause external force and be 0 diffusion coefficient D greater than external force ₀With C ₀Infinitely-great diffusion concentration of the time that is set at, then the C under the external force is shown in formula (21).

$C=\frac{{\mathrm{<figure-callout\; id="0"\; label="C"\; filenames="HDA00002005692900071.png,HDA00002005692900082.png"\; state="\{\{state\}\}">C</figure-callout>}}_0}{2\sqrt{\mathrm{\&pi;}{D}_{F}t}}\exp (-\frac{x^2}{4D_{F}t})\&CenterDot;\&CenterDot;\&CenterDot;\left(21\right)$

According to formula (21), the time-dependent of the concentration of fixed point is shown in following formula (22), (23).

$C\left(t\right)\&Proportional;\exp (-\frac{d^2}{4\mathrm{Dt}})\&CenterDot;\&CenterDot;\&CenterDot;\left(22\right)$

$C\left(t\right)=\mathrm{Aexp}(-\frac{a}{t}),a=\frac{d^2}{4D}\&CenterDot;\&CenterDot;\&CenterDot;\left(23\right)$

All experimental results of the material discharger that uses embodiment of the present invention are described then.

(experiment 1)

In experiment 1, seek ejected matter with respect to the relation of the drift velocity that is discharged from body 200.

In experiment, as shown in Figure 5, use the agar as being discharged from body 200, as the material suitable, prepared different 3 kinds of molecular weight with ejected matter.Specifically, as sample 1, the sample after use will be infiltrated in the agar 111 as ejected matter as the redness No. 102 (molecular weight 631.51) of colouring matter.As sample 2, the sample after use will be infiltrated in the agar 111 as ejected matter as the blueness No. 1 (molecular weight 792.86) of colouring matter.As sample 3, the sample after use will be infiltrated in the agar 111 as ejected matter as the insulin (molecular weight 5807) of medicament.

Agar 111 times, be filter paper configuration vibration section 120 across the ejected matter absorber 110 of Fig. 1, on agar 111, place weight 112, so that hyperacoustic vibration is delivered to agar 111 easily.Under this state, through the 120 pairs of agars 111 in vibration section ultrasound wave that vibrates successively.Change hyperacoustic frequency of oscillation, seek this frequency of oscillation and the relation of concentration that absorbs the ejected matter of filter paper from each sample.The result can know, for each sample, aspect the relation of the concentration of synthetic frequency of oscillation of ultrasonic amplitude and ejected matter, describes the different curve that distributes.Confirm from above, in each ejected matter,, have the inherent drift velocity corresponding with its molecular weight aspect the relation of non-discharge body.

(experiment 2)

In experiment 2, according to the comparison of comparative example, seek the discharge dominance of drain position of the material discharger of this embodiment.

In experiment, the same with Fig. 5, as being discharged from body 200, after will infiltrating in the agar 111 as ejected matter No. 102 as the redness of colouring matter, use is discharged from body.Agar 111 times, be filter paper configuration vibration section 120 across the ejected matter absorber 110 of Fig. 1, on agar 111, place weight 112.Under this state, as embodiment, the Modulation and Amplitude Modulation ultrasound wave of the zigzag fashion through 120 pairs of agars in vibration section 111 vibration negative gradients.And; In order to compare with embodiment; At agar 111 times configuration filter paper, be placed with on the agar 111 under the state of weight 112, carry out comparative example 1 and comparative example 2, comparative example 1 is only to make according to Concentraton gradient to spread naturally towards filter paper for red No. 102; Comparative example 2 is under the state identical with Fig. 5, to the ultrasound wave of agar 111 vibration fixed amplitudes.

Fig. 6 illustrates the figure as the photo of each filter paper after No. 102 diffusions of redness of ejected matter according to embodiment and comparative example 1,2 in experiment 2.

In Fig. 6; Sample A is the filter paper after in the diffusion naturally of comparative example 1, having placed 3 minutes; Sample B is the filter paper of ultrasound wave after 3 minutes of fixed amplitude of comparative example 2 of having vibrated, and sample C is the filter paper after the Modulation and Amplitude Modulation ultrasound wave of zigzag fashion of the negative gradient of embodiment was vibrated 3 minutes with 0.1 second vibration period.

Can know that from the photo of Fig. 6 for Sample A and sample B, red No. 102 concentration difference is a little, and for sample C, compares with Sample A, B, red No. 102 concentration is very big.

Then, to Sample A, B, C, seek the relation of the concentration of experimental period and red 102 colors.Fig. 7 illustrates experimental result.

In Fig. 7; (for Sample A is standing time with experimental period; For sample B, C is hyperacoustic duration of oscillation) be made as 60 seconds, 120 seconds, 180 seconds, 300 seconds, 600 seconds; Make each filter paper of the Sample A that absorbed red No. 102, B, C dissolve in distilled water, through its absorbance of beam splitter instrumentation (Abs).The approximate data of Fig. 7 is the absorbance that calculates according to formula (22), (23).

Can confirm from the experimental result of Fig. 7,, compare with Sample A, the B of comparative example 1,2 and to present high absorbance for the sample C of embodiment.

To embodiment and comparative example 1,2, Fig. 8 A～Fig. 8 C illustrates the difference of experiment value and approximate data.Fig. 8 A is a comparative example 1, and approximate data is to investigate the nature diffusion and the absorbance of acquisition.Fig. 8 B is a comparative example 2, and approximate data is to investigate ultrasound wave is taken as the situation of fixed amplitude and the absorbance that obtains.Fig. 8 C is embodiment, and approximate data is the absorbance that calculates according to formula (22), (23).

Probable error in each example is 1 ± 0.141 in the comparative example 1 of Fig. 8 A, in the comparative example 2 of Fig. 8 B, is 1 ± 0.017, in the comparative example 1 of Fig. 8 C, is 1 ± 0.004.Can confirm that from this result for embodiment, compare with comparative example 1,2, probable error is minimum.

Can use formula (21), utilize the result of least-square analysis experiment 2.

According to the result of above-mentioned experiment 1, through the use nonlinear least square method, but the value of design factor a.

Value according to the coefficient a that calculates; To the comparative example 1 of working concentration gradient only, use fixed amplitude hyperacoustic comparative example 2, use the each side of the hyperacoustic embodiment of Modulation and Amplitude Modulation of zigzag fashion of the negative gradient of this embodiment, the value of calculation flow rate J.Fig. 9 illustrates its result.In Fig. 9, the flow velocity J during with working concentration gradient only is as reference value 1, with the flow velocity J of comparative example 2 and embodiment as relative value.In an embodiment, obtain about 2 times flow velocity of comparative example 1,2.Can confirm thus, use the discharge effectiveness of the hyperacoustic ejected matter of Modulation and Amplitude Modulation of the negative gradient zigzag fashion of this embodiment.

That is susceptible of proof: consider drift velocity (V _d) Modulation and Amplitude Modulation ultrasound wave group is provided, and it is spread naturally, or continue to provide the ultrasound wave of fixed amplitude to compare, can realize effective discharge of ejected matter.

That kind as described above according to this embodiment, is directed against the drift velocity-V that is discharged from body 200 according to ejected matter _d, the amplitude of control from each ultrasound wave of the Modulation and Amplitude Modulation ultrasound wave group of vibration section 120 vibration, thereby, realize the effective discharge corresponding with this ejected matter when the surface that is discharged from body of human body etc. uses ultrasound wave to discharge ejected matter.

The content that material discharger of the present invention for example can be applicable to acne is that sebum is as ejected matter and with its treatment of effectively discharging; Perhaps can be applicable to substance in vivos such as pus, blood stasis, transudate are discharged to external surgical operation, promptly so-called drainage.

In this embodiment; In control part 130; According to information from the ejected matter of information input unit 140 input, carry out from each ultrasound wave of the Modulation and Amplitude Modulation ultrasound wave group of vibration section 120 vibrations amplitude control and as each hyperacoustic quantity control of 1 Modulation and Amplitude Modulation ultrasound wave group vibration, yet be not limited to this in the present invention; For example; Can be following form: except the information of the ejected matter shown in this embodiment, also import the information of the acoustic impedance of being measured that is discharged from body 200, except the information of ejected matter from information input unit 140; Also consider the information of this acoustic impedance, carry out each hyperacoustic amplitude of the Modulation and Amplitude Modulation ultrasound wave group of 120 vibrations and control and control as each hyperacoustic quantity that 1 Modulation and Amplitude Modulation ultrasound wave group is vibrated from the vibration section.

(modified example)

Below, the modified example of this embodiment is described.In this modified example, disclosing the apparatus structure identical with Fig. 1 of this embodiment is material discharger, yet is that the oscillatory regime of its Modulation and Amplitude Modulation ultrasound wave group is slightly different with the difference of this embodiment.

Figure 10 is the performance plot that the Modulation and Amplitude Modulation ultrasound wave group of the skin that is discharged from body being vibrated from supersonic oscillations portion is shown.The diffusion of ejected matter (from the diffusion to the outside of the skin that is discharged from body) is that the linearity of nature diffusion and the external force diffusion that 120 ultrasound wave that vibrate as Modulation and Amplitude Modulation ultrasound wave group cause from the vibration section combines.Naturally diffusion only based on the diffusion depth of Concentraton gradient by shown in the following formula (24).

［ formula 18 ］

$d=\sqrt{2\mathrm{Dt}}-L\&CenterDot;\&CenterDot;\&CenterDot;\left(24\right)$

In this modified example; Control part 130 adds from the vibration section external force diffusion that 120 ultrasound wave that vibrate as Modulation and Amplitude Modulation ultrasound wave group cause with the above-mentioned effect of diffusion naturally; According to the vibration of each Modulation and Amplitude Modulation ultrasound wave group of the negative gradient control of vibrating in proper order, so that amplitude increases.

Like this; Through control that each Modulation and Amplitude Modulation ultrasound wave group is vibrated; Make at the amplitude of the initial Modulation and Amplitude Modulation ultrasound wave group of vibration for a short time, thereby increase that ejected matter increases to the scanning times on the surface that is discharged from body based on the handover number of times of the ejected matter of the drift velocity of time per unit.Thus, the discharge efficient of ejected matter further improves.

In addition, in this embodiment and modified example, suppose that human body is described as being discharged from body 200, yet be not limited to this in the present invention, also can be applied to other animal.

And, be discharged from body except live body, for example can also use clothes etc.,, also can the dirt that material discharger of the present invention is applied to clothes etc. be removed as ejected matter with the dirt of clothes etc.

Each the unitary function of control part 30 of Fig. 1 that constitutes the material discharger 100 of aforementioned embodiment can realize through program in the RAM that is stored in computer and the ROM etc. is moved.This program and the storage medium that has write down the embodied on computer readable of this program are included in the present invention.

Specifically, said program is recorded in the such storage medium of CD-ROM for example, perhaps is provided for computer via various transmission mediums.Storage medium as the said program of record except CD-ROM, also can use floppy disk, hard disk, tape, photomagneto disk, Nonvolatile memory card etc.On the other hand, as the transmission medium of said program, can use to be used for propagating as carrier wave and the communication media of computer network (WAN such as LAN, the Internet, the cordless communication network etc.) system that provides with program information.And,, can enumerate Wireline such as optical fiber and radiolink etc. as the communication media of this moment.

And; Not only through carrying out the function that the program that is provided realizes the material discharger 100 of this embodiment by computer; And under the situation of the function of the common material discharger 100 of realizing this embodiment such as the OS (operating system) that in computer, works with this program or other application software; Perhaps under the situation of the function of all or part of material discharger 100 of realizing this embodiment by the expansion board or the functional expansion unit of computer of the processing of the program that is provided, this program is also contained in the present invention.

Utilizability on the industry

According to the present invention, can use ultrasonic vibration, from the surface that is discharged from body of human body etc. ejected matter is discharged to the outside that this is discharged from body, can realize the effective discharge corresponding with this ejected matter.

Claims (9)

1. material discharger, said material discharger is discharged to the outside from the surface that is discharged from body with ejected matter, it is characterized in that, and said material discharger has:

Supersonic oscillations portion, the Modulation and Amplitude Modulation ultrasound wave group it is modulated each hyperacoustic amplitude the said surface oscillation that is discharged from body with mode decrescence after; And

Control part, it with respect to the said drift velocity that is discharged from body, controls each hyperacoustic amplitude of said Modulation and Amplitude Modulation ultrasound wave group according to said ejected matter.

2. material discharger according to claim 1; It is characterized in that; Said each the hyperacoustic amplitude of said control part control makes that the absolute value of gradient in the elapsed time of each hyperacoustic amplitude with respect to from the starting of oscillation of said Modulation and Amplitude Modulation ultrasound wave group time of said Modulation and Amplitude Modulation ultrasound wave group is below the said drift velocity.

3. material discharger according to claim 1 is characterized in that, said control part determines said each hyperacoustic quantity of vibrating as said Modulation and Amplitude Modulation ultrasound wave group according to the output of the said ejected matter that sets.

4. material discharger according to claim 3; It is characterized in that; Said control part is controlled as follows: the initial ultrasound wave during from the starting of oscillation of said Modulation and Amplitude Modulation ultrasound wave group; Till the last ultrasound wave of hyperacoustic quantity of vibrating of said decision, make dull minimizing of each hyperacoustic amplitude of said Modulation and Amplitude Modulation ultrasound wave group.

5. material discharger according to claim 4; It is characterized in that; Said control part is after said last hyperacoustic control of having carried out said Modulation and Amplitude Modulation ultrasound wave group; Carry out being controlled to the zigzag fashion that is shaped as negative gradient that makes this Modulation and Amplitude Modulation ultrasound wave group from the control of said supersonic oscillations portion next Modulation and Amplitude Modulation ultrasound wave group of vibration.

6. material discharger according to claim 5 is characterized in that, said control part becomes to make amplitude to increase by the vibration sequential control of each said Modulation and Amplitude Modulation ultrasound wave group.

7. material discharger according to claim 1 is characterized in that, said supersonic oscillations portion has the ring-type oscillator in the abutment portion with the surface that is discharged from body.

8. material discharger according to claim 1 is characterized in that, said material discharger also has:

Storage part, its kind by said ejected matter is stored the value of said drift velocity; And

Information input unit, it imports the kinds of information of the said ejected matter of actual discharge at least,

Said control part is controlled the amplitude of said Modulation and Amplitude Modulation ultrasound wave group according to the value of extracting corresponding drift velocity from the kind of the said ejected matter of said information input unit input from said storage part according to the value of this drift velocity that extracts.

9. material discharger according to claim 1 is characterized in that, said control part has: test section, and it detects from each ultrasound wave of the said Modulation and Amplitude Modulation ultrasound wave group of said supersonic oscillations portion vibration; And the configuration part, it controls each hyperacoustic phase contrast of this Modulation and Amplitude Modulation ultrasound wave group according to by detected said each ultrasound wave of said test section, and said supersonic oscillations portion is set at resonance state.

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