CN102628806A - Method for improving laser Raman spectrum detection sensitivity with molecularly imprinted material - Google Patents
Method for improving laser Raman spectrum detection sensitivity with molecularly imprinted material Download PDFInfo
- Publication number
- CN102628806A CN102628806A CN2012100801814A CN201210080181A CN102628806A CN 102628806 A CN102628806 A CN 102628806A CN 2012100801814 A CN2012100801814 A CN 2012100801814A CN 201210080181 A CN201210080181 A CN 201210080181A CN 102628806 A CN102628806 A CN 102628806A
- Authority
- CN
- China
- Prior art keywords
- laser raman
- raman spectrometer
- detection sensitivity
- dinitroglycol
- molecular engram
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Abstract
Belonging to the technical field of laser Raman spectrum detection, the invention relates to a method for improving laser Raman spectrum detection sensitivity with a molecularly imprinted material. Detection with a portable laser Raman spectrometer comprises the steps of: placing a sample to be detected into a transparent glass bottle, then putting the glass bottle into a sample cell, making a probe of the laser Raman spectrometer and the molecularly imprinted material act on the sample to be detected simultaneously for detection; and before detection, setting the power and integration time of the laser Raman spectrometer respectively at 10-100mW and 1-20s. The method of the invention can improve the detection sensitivity of the laser Raman spectrometer.
Description
Technical field
The present invention relates to adopt molecular engram material to improve the method for laser Raman spectroscopy detection sensitivity, belong to laser Raman spectroscopy detection technique field.
Background technology
Because the vibration and the rotational energy level of Raman shift and molecule are relevant, the vibration of different material molecule and rotational energy level are different, thereby different Raman shifts are arranged, promptly different Raman spectrums.Utilize Raman spectrum to carry out structure analysis and qualitative detection to material molecule; Thereby can be used for material differentiates; Liquid blasting material Detection Techniques based on Raman spectroscopy are becoming the research focus; The product of at present American-European existing this type technology in safety check market is being used, and domesticly also can buy this series products, but costs an arm and a leg.In addition, existing Raman spectrum rays safety detection apparatus all can only be surveyed the liquid in the transparent vessel under in-plant situation, in practical application, has significant limitation, and result of use is not good.
The molecular recognition polymkeric substance of synthetic is compared with natural molecule identification material; Have the advantage that structure is imitated precordainment, specific recognition property, be widely used in biology sensor, SPE, clinical medicine analysis, analogue enztme and aspects such as Chinese herbal medicine effective ingredients separates.
Summary of the invention
The objective of the invention is to adopt molecular engram material to improve the method for laser Raman spectroscopy detection sensitivity in order to propose.
The objective of the invention is to realize through following technical scheme.
Employing molecular engram material of the present invention improves the method for laser Raman spectroscopy detection sensitivity; Adopt the portable laser Raman spectrometer to detect; Concrete steps are: testing sample is put in the transparent vial; Then vial is put in the sample cell of laser Raman spectrometer, the probe and the molecular engram material of laser Raman spectrometer acted on the testing sample simultaneously, detect; The power and the integral time of setting laser Raman spectrometer before detecting; Power is 10～100mW, and be 1～20s integral time.
Beneficial effect
Method of the present invention can improve the detection sensitivity of laser Raman spectrometer.
Description of drawings
The Raman spectrum collection of illustrative plates that Fig. 1 obtains for embodiment.
Embodiment
Embodiment
Adopt the dinitroglycol molecular engram film to improve the sensitivity of method that laser Raman spectroscopy detects dinitroglycol; Adopt the portable laser Raman spectrometer to detect; Concrete steps are: the WS that with mass concentration is 30% dinitroglycol is put in the transparent vial; Then vial is put in the sample cell of laser Raman spectrometer, the dinitroglycol molecular engram film is coated on the probe of laser Raman spectrometer, then dinitroglycol is detected; The power and the integral time of setting laser Raman spectrometer before detecting; Power is 50mW, and be 1s integral time, obtains the Raman spectrum collection of illustrative plates, and its spectrogram is as shown in Figure 1, by knowing 1648cm among the figure
-1(w-m) be NO
2The asymmetric stretching vibration peak, 1284cm
-1(vs) be NO
2The symmetrical stretching vibration peak, 560cm
-1(m) be NO
2The deformation vibration peak, 1039cm
-1(m-s) be the C-C-O stretching vibration peak, 479cm
-1(w-m) be the deformation vibration peak of C-C-O, 852cm
-1(w) be-CH
2-the in-plane bending vibration peak.
The comparative example
With the dinitroglycol mass concentration is that 30% sample is put in the transparent vial, then vial is put in the sample cell of laser Raman spectrometer, and dinitroglycol is detected; The power and the integral time of setting laser Raman spectrometer before detecting; Power is 50mW, and be 1s integral time, is almost the characteristic peak that dinitroglycol does not appear in straight line in the spectrogram that obtains.
Can know by embodiment and Comparative Examples; Be under 30% the situation in the concentration of dinitroglycol; The characteristic peak of dinitroglycol can appear in employing dinitroglycol molecular engram film when detecting dinitroglycol, when not using molecular engram film, then can not detect the characteristic peak of dinitroglycol.
Claims (2)
1. adopt molecular engram material to improve the method for laser Raman spectroscopy detection sensitivity; It is characterized in that: adopt the portable laser Raman spectrometer to detect; Concrete steps are: testing sample is put in the transparent vial; Then vial is put in the sample cell of laser Raman spectrometer, the probe and the molecular engram material of laser Raman spectrometer acted on the testing sample simultaneously, detect; The power and the integral time of setting laser Raman spectrometer before detecting; Power is 10～100mW, and be 1～20s integral time.
2. employing molecular engram material according to claim 1 improves the method for laser Raman spectroscopy detection sensitivity, and it is characterized in that: the molecular engram film of employing is a dinitroglycol, improves the sensitivity that laser Raman spectroscopy detects dinitroglycol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012100801814A CN102628806A (en) | 2012-03-23 | 2012-03-23 | Method for improving laser Raman spectrum detection sensitivity with molecularly imprinted material |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012100801814A CN102628806A (en) | 2012-03-23 | 2012-03-23 | Method for improving laser Raman spectrum detection sensitivity with molecularly imprinted material |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102628806A true CN102628806A (en) | 2012-08-08 |
Family
ID=46587105
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012100801814A Pending CN102628806A (en) | 2012-03-23 | 2012-03-23 | Method for improving laser Raman spectrum detection sensitivity with molecularly imprinted material |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102628806A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4714345A (en) * | 1984-06-29 | 1987-12-22 | Bernhard Schrader | Sample arrangement for spectrometry, method for the measurement of luminescence and scattering and application of the sample arrangement |
| JP2006030122A (en) * | 2004-07-21 | 2006-02-02 | Atokku:Kk | Raman spectrum spectroscope |
| CN102539408A (en) * | 2011-12-12 | 2012-07-04 | 北京理工大学 | Method for improving detection sensitivity of laser Raman spectroscopy by using molecularly imprinted material |
-
2012
- 2012-03-23 CN CN2012100801814A patent/CN102628806A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4714345A (en) * | 1984-06-29 | 1987-12-22 | Bernhard Schrader | Sample arrangement for spectrometry, method for the measurement of luminescence and scattering and application of the sample arrangement |
| JP2006030122A (en) * | 2004-07-21 | 2006-02-02 | Atokku:Kk | Raman spectrum spectroscope |
| CN102539408A (en) * | 2011-12-12 | 2012-07-04 | 北京理工大学 | Method for improving detection sensitivity of laser Raman spectroscopy by using molecularly imprinted material |
Non-Patent Citations (2)
| Title |
|---|
| 刘泽权等: "《激光拉曼光谱法快速检验硝酸乙酯》", 《全国危险物质与安全应急技术研讨会论文集》, 10 December 2011 (2011-12-10), pages 2 - 2 * |
| 王虎等: "《分子印迹技术在硝酸酯检测中的应用》", 《全国危险物质与安全应急技术研讨会论文集》, 10 December 2011 (2011-12-10) * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102455320B (en) | Wine origin identification technical method | |
| CN103293141B (en) | A liquor vintage recognition method based on a fusion technology of ion mobility spectrometry/ mass spectrometry/ Raman spectroscopy | |
| Park et al. | Analysis of the CO2 and NH3 reaction in an aqueous solution by 2D IR COS: Formation of bicarbonate and carbamate | |
| CN102749349B (en) | A kind of method differentiating authenticity of hide glue | |
| WO2013157917A3 (en) | A biosensor and preparation method thereof | |
| CN107255685A (en) | The high performance liquid chromatography of ultraviolet absorber in a kind of detection cosmetics | |
| CN103487399A (en) | Terahertz time-domain spectroscopy method for quantitatively detecting tetracycline hydrochloride solutions | |
| CN102680561A (en) | Method for measuring boric acid in water-based adhesive for cigarettes | |
| EP2559997A3 (en) | Method and apparatus for capturing and retesting of an online toc excursion sample | |
| CN104897731B (en) | A kind of horizontal detection means of portable plant nutrient | |
| CN108802240A (en) | The extraction of cannabinoid compound and detection method in hair | |
| CN103245713B (en) | Based on the Chinese herbal medicine place of production discrimination method of support vector machine and ion mobility spectrometry | |
| CN102539409A (en) | Method for increasing detection sensitivity of laser Raman spectroscopy by adopting molecularly imprinted material | |
| CN103868916B (en) | Biological test method for rapidly detecting comprehensive toxicity of traditional Chinese medicine | |
| CN102768191B (en) | Method for easily detecting trace thallium in water | |
| CN104237206A (en) | Analytical method for measuring contents of iron, manganese, aluminum, titanium, nickel, calcium and magnesium in silica powder | |
| CN105092557A (en) | Method for utilizing Raman spectrum to rapidly detect free amino acid content of yellow rice wine | |
| RU2012128655A (en) | METHOD AND DEVICE FOR CREATION OF AUTOMATIC SAMPLER FOR DETECTION OF SALMONELLA ENTERICA USING ELECTROCHEMICAL BIOSENSOR WITH APTAMERS | |
| CN105277510A (en) | Propiconazole discriminating method based on Terahertz theory for simulation of spectrum database | |
| CN102539408A (en) | Method for improving detection sensitivity of laser Raman spectroscopy by using molecularly imprinted material | |
| CN102621124A (en) | Method for improving detection sensitivity of laser-Raman spectrum through adopting molecularly imprinted material | |
| CN102879499A (en) | Method for detecting antioxidant constituents in nitraria fruit juice by using 1,1-diphenyl-2-picrylhydrazyl (DPPH)-high performance liquid chromatography (HPLC) method | |
| CN102628806A (en) | Method for improving laser Raman spectrum detection sensitivity with molecularly imprinted material | |
| CN116541750A (en) | Identification method of coix seed origin, terminal equipment and storage medium | |
| CN202676589U (en) | Portable rapid detecting and identifying equipment for mine water source |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20120808 |