CN102621124A - Method for improving detection sensitivity of laser-Raman spectrum through adopting molecularly imprinted material - Google Patents
Method for improving detection sensitivity of laser-Raman spectrum through adopting molecularly imprinted material Download PDFInfo
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- CN102621124A CN102621124A CN2012100802516A CN201210080251A CN102621124A CN 102621124 A CN102621124 A CN 102621124A CN 2012100802516 A CN2012100802516 A CN 2012100802516A CN 201210080251 A CN201210080251 A CN 201210080251A CN 102621124 A CN102621124 A CN 102621124A
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- laser
- laser raman
- raman spectrometer
- detection sensitivity
- detection
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Abstract
The invention belongs to the technical field of laser-Raman spectrum detection, and relates to a method for improving detection sensitivity of a laser-Raman spectrum through adopting molecularly imprinted material. A portable laser-Raman spectrometer is adopted for detection, and the method comprises specific steps as follows: placing a to-be-detected sample into a transparent glass bottle, placing the glass bottle in a sample cell of the laser-Raman spectrometer, and enabling the laser-Raman spectrometer and the molecularly imprinted material to act on the to-be-detected sample simultaneously, so as to carry out detection; setting the power and integral time of the laser-Raman spectrometer before detection; and setting the power as 10-100mW, and setting the integral time as 1-20s. The method disclosed by the invention can improve the detection sensitivity of the laser-Raman spectrum.
Description
Technical field
The present invention relates to adopt molecular engram material to improve the method for laser Raman spectroscopy detection sensitivity, belong to laser Raman spectroscopy detection technique field.
Background technology
Because the vibration and the rotational energy level of Raman shift and molecule are relevant, the vibration of different material molecule and rotational energy level are different, thereby different Raman shifts are arranged, promptly different Raman spectrums.Utilize Raman spectrum to carry out structure analysis and qualitative detection to material molecule; Thereby can be used for material differentiates; Liquid blasting material Detection Techniques based on Raman spectroscopy are becoming the research focus; The product of at present American-European existing this type technology in safety check market is being used, and domesticly also can buy this series products, but costs an arm and a leg.In addition, existing Raman spectrum rays safety detection apparatus all can only be surveyed the liquid in the transparent vessel under in-plant situation, in practical application, has significant limitation, and result of use is not good.
The molecular recognition polymkeric substance of synthetic is compared with natural molecule identification material; Have the advantage that structure is imitated precordainment, specific recognition property, be widely used in biology sensor, SPE, clinical medicine analysis, analogue enztme and aspects such as Chinese herbal medicine effective ingredients separates.
Summary of the invention
The objective of the invention is to adopt molecular engram material to improve the method for laser Raman spectroscopy detection sensitivity in order to propose.
The objective of the invention is to realize through following technical scheme.
Employing molecular engram material of the present invention improves the method for laser Raman spectroscopy detection sensitivity; Adopt the portable laser Raman spectrometer to detect; Concrete steps are: testing sample is put in the transparent vial; Then vial is put in the sample cell of laser Raman spectrometer, the probe and the molecular engram material of laser Raman spectrometer acted on the testing sample simultaneously, detect; The power and the integral time of setting laser Raman spectrometer before detecting; Power is 10～100mW, and be 1～20s integral time.
Beneficial effect
Method of the present invention can improve the detection sensitivity of laser Raman spectrometer.
Description of drawings
Fig. 1 is the laser Raman spectroscopy spectrogram of n-Propyl Nitrate.
Embodiment
Embodiment
Adopt the n-Propyl Nitrate molecular engram film to improve the sensitivity of method that laser Raman spectroscopy detects n-Propyl Nitrate; Adopt the portable laser Raman spectrometer to detect; Concrete steps are: the WS that with mass concentration is 30% n-Propyl Nitrate is put in the transparent vial; Then vial is put in the sample cell of laser Raman spectrometer, the n-Propyl Nitrate molecular engram film is coated on the probe of laser Raman spectrometer, then n-Propyl Nitrate is detected; The power and the integral time of setting laser Raman spectrometer before detecting; Power is 50mW, and be 1s integral time, and the spectrogram that obtains is as shown in Figure 1, by knowing 2956cm among the figure
-1Be CH
3In-plane bending vibration, 859cm
-1Be terminal methyl group rocking vibration, 567cm
-1Be NO
2Deformation vibration, 1276cm
-1Be NO
2Symmetrical stretching vibration, 2949cm
-1Be CH
2In-plane bending vibration.
The comparative example
With the n-Propyl Nitrate mass concentration is that 30% sample is put in the transparent vial, then vial is put in the sample cell of laser Raman spectrometer, and n-Propyl Nitrate is detected; The power and the integral time of setting laser Raman spectrometer before detecting; Power is 50mW, and be 1s integral time, does not occur the characteristic peak of n-Propyl Nitrate in the spectrogram that obtains.
Claims (2)
1. adopt molecular engram material to improve the method for laser Raman spectroscopy detection sensitivity; It is characterized in that: adopt the portable laser Raman spectrometer to detect; Concrete steps are: testing sample is put in the transparent vial; Then vial is put in the sample cell of laser Raman spectrometer, the probe and the molecular engram material of laser Raman spectrometer acted on the testing sample simultaneously, detect; The power and the integral time of setting laser Raman spectrometer before detecting; Power is 10～100mW, and be 1～20s integral time.
2. employing molecular engram material according to claim 1 improves the method for laser Raman spectroscopy detection sensitivity, and it is characterized in that: the molecular engram film of employing is a n-Propyl Nitrate, improves the sensitivity that laser Raman spectroscopy detects n-Propyl Nitrate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012100802516A CN102621124A (en) | 2012-03-23 | 2012-03-23 | Method for improving detection sensitivity of laser-Raman spectrum through adopting molecularly imprinted material |
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| CN2012100802516A CN102621124A (en) | 2012-03-23 | 2012-03-23 | Method for improving detection sensitivity of laser-Raman spectrum through adopting molecularly imprinted material |
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| CN102621124A true CN102621124A (en) | 2012-08-01 |
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| CN2012100802516A Pending CN102621124A (en) | 2012-03-23 | 2012-03-23 | Method for improving detection sensitivity of laser-Raman spectrum through adopting molecularly imprinted material |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103304352A (en) * | 2012-08-20 | 2013-09-18 | 北京理工大学 | N-propyl nitrate full-simulation explosive simulant |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4714345A (en) * | 1984-06-29 | 1987-12-22 | Bernhard Schrader | Sample arrangement for spectrometry, method for the measurement of luminescence and scattering and application of the sample arrangement |
| JP2006030122A (en) * | 2004-07-21 | 2006-02-02 | Atokku:Kk | Raman spectrum spectroscope |
| CN102539409A (en) * | 2011-12-12 | 2012-07-04 | 北京理工大学 | Method for increasing detection sensitivity of laser Raman spectroscopy by adopting molecularly imprinted material |
-
2012
- 2012-03-23 CN CN2012100802516A patent/CN102621124A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4714345A (en) * | 1984-06-29 | 1987-12-22 | Bernhard Schrader | Sample arrangement for spectrometry, method for the measurement of luminescence and scattering and application of the sample arrangement |
| JP2006030122A (en) * | 2004-07-21 | 2006-02-02 | Atokku:Kk | Raman spectrum spectroscope |
| CN102539409A (en) * | 2011-12-12 | 2012-07-04 | 北京理工大学 | Method for increasing detection sensitivity of laser Raman spectroscopy by adopting molecularly imprinted material |
Non-Patent Citations (2)
| Title |
|---|
| 刘泽权，刘吉平等: "激光拉曼光谱法快速检验硝酸乙酯", 《全国危险物质与安全应急技术研讨会论文集》 * |
| 王虎、刘吉平等: "分子印迹技术在硝酸酯检测中的应用", 《全国危险物质与安全应急技术研讨会论文集》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103304352A (en) * | 2012-08-20 | 2013-09-18 | 北京理工大学 | N-propyl nitrate full-simulation explosive simulant |
| CN103304352B (en) * | 2012-08-20 | 2015-10-14 | 北京理工大学 | N-propyl nitrate full-simulation explosive simulant |
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Application publication date: 20120801 |