CN102183408B - Three-point or four-point bending fatigue test fixture for living rat ulna - Google Patents
Three-point or four-point bending fatigue test fixture for living rat ulna Download PDFInfo
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- CN102183408B CN102183408B CN2011100604099A CN201110060409A CN102183408B CN 102183408 B CN102183408 B CN 102183408B CN 2011100604099 A CN2011100604099 A CN 2011100604099A CN 201110060409 A CN201110060409 A CN 201110060409A CN 102183408 B CN102183408 B CN 102183408B
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Abstract
The invention discloses a three-point or four-point bending fatigue test fixture for a living rat ulna. The fixture comprises a carrying disc and a foreleg uploading test device, wherein the carrying disc is arranged in a test chamber; the foreleg uploading test device comprises an upper connecting rod, an upper spring connection shaft, a linear elastic spring, a lower spring connection shaft, a T-shaped upper pressure head slide carriage, upper pressure heads, lower support heads, a C-shaped lower slide carriage and a lower connecting rod; the C-shaped lower slide carriage is mounted on the lower connecting rod connected with a main engine load sensor, and the upper end of the C-shaped lower slide carriage is provided with at least two guide pillars; a linear bearing capable of enabling the T-shaped upper pressure head slide carriage to move up and down along the guide pillars is mounted on the T-shaped upper pressure head slide carriage, the top of the T-shaped upper pressure head slide carriage is provided with the lower spring connection shaft connected with the lower end of the linear elastic spring, the upper end of the linear elastic spring is mounted on the lower end of the upper spring connection shaft, and the upper spring connection shaft is mounted at the lower end of the upper connecting rod; and one or more upper pressure heads are arranged under the T-shaped upper pressure head slide carriage, two lower support heads are arranged on the C-shaped lower slide carriage corresponding to the lower part of the upper pressure heads, and the carrying disc is mounted under the lower support heads. The fixture provided by the invention can take a living rat as a carrier, and is simple in structure, convenient to use, precise in acting points, accurate in location and more excellent in microdamage research, thereby being suitable for performing the three-point or four-point bending fatigue test on the living rat ulna.
Description
Technical field
The present invention relates to a kind of mechanism that clamps, 3 of especially a kind of live body mouse ulnas or four-point bending fatigue test clamper.
Background technology
The measurement of experiment made on the living mouse bone loading force mathematic(al) parameter is the basic research of setting up biomechanics of bone correlation theory and practical application; Carry out clamping and utilize experiment made on the living mouse ulna to clamp mechanism; On Experiments of Machanics equipment, ulna is carried out dynamic and static loading experiment; Can the load one adaptability to changes mathematic(al) parameter of test experiments mouse ulna under the different loads situation, draw the stress-strain curve of its ulna.Simultaneously, the various different loads of can further analyzing and researching produce tired micro-damage to experimental mouse ulna skeletal tissue, for correlation theory researchs such as biomechanics of bone, bone tissue engineer, pathology, pharmacology provide foundation.
At present experiment made on the living mouse bone loads Experiments of Machanics and mainly adopts two kinds of axial compression and four-point bending torture tests; State, inside and outside major part are to adopt the tired mode of axial compression to obtain sample micro-damage and fatigue fracture; Like Chinese patent; The patent No. is: CN200910197437.8, patent name is: the patent of mechanism for axially loading and clamping ulna of in-vivo experimental rat, employing be the mode that a kind of experiment made on the living mouse ulna axially loads compression; But adopt the axial compression center of effort usually indeterminate, the micro-damage position is difficult for confirming; And the tired location of four-point bending accurately, and the tension force center of effort that deformation produced is clear and definite, can produce obvious micro-damage and stress fracture; Remedied that the tension force center of effort that axle property compression set produced is indeterminate, micro-damage is not easy to shortcomings such as location, be of value to micro-damage research, but the present device that clamps that does not also have four-point bending test; Particularly do not adopt the four-point bending test device of live body, and require between two upper pressure point, to produce pure bending power in the four-point bending test, and shearing force is zero; And the dynamics on each pressure point must equate; Technical difficulty is bigger, does not particularly have unit clamp for the live body rat, and test is difficult to carry out.
Summary of the invention
The objective of the invention is to overcome the deficiency of prior art and provide a kind of simple in structure, easy to use, can adopt the live body mouse as carrier, center of effort accurately, accurate positioning, be used for 3 of the live body mouse ulnas or the four-point bending fatigue test clamper of micro-damage research better.
The object of the invention is achieved through following technical proposals:
3 of a kind of live body mouse ulnas or four-point bending fatigue test clamper; Comprise the loading dish and the forelimb load testing machine that are installed in the chamber; Said forelimb load testing machine comprises coupling shaft under coupling shaft on upper connecting rod, the spring, linear elasticity spring, the spring, T type seaming chuck slide, seaming chuck, following supporting member, C type lower slider, lower connecting rod; On the said lower connecting rod that said C type lower slider is installed in the main unit load sensor is connected; The upper end of said C type lower slider is provided with at least two guide pillars; The said linear bearing that said T type seaming chuck slide ability is moved up and down along said guide pillar is installed on the said T type seaming chuck slide, and the top of said T type seaming chuck slide is provided with coupling shaft under the said spring that is connected with said linear elasticity spring lower end, and the upper end of said linear elasticity spring is installed in the lower end of coupling shaft on the said spring; Coupling shaft is installed in the lower end of said upper connecting rod on the said spring; The below of said T type seaming chuck slide is provided with one or two seaming chuck, and the below of corresponding said seaming chuck is provided with two following supporting members on the said C type lower slider, and said loading dish is installed in the said below of supporting member down.
Among the present invention; The bracing frame that supports the loading dish also is installed in the said chamber; The lower end of support frame as described above is provided with stationary installation and is installed in the said chamber; The upper end of support frame as described above is provided with spiral lifting mechanism, and the top of said spiral lifting mechanism is provided with slideway, and the lower end of said loading dish is provided with the guide rail that is installed in the said slideway.
Among the present invention; The below of said T type seaming chuck slide laterally is provided with chute; Be provided with one or two seaming chuck in the said chute, said seaming chuck is fixed in the said chute through first holding screw and said seaming chuck can move at chute through the adjusting of said first holding screw.
Among the present invention, the below of said C type lower slider laterally is provided with chute, and said two following supporting members are fixed in the said chute through second holding screw and said supporting member down can move at chute through the adjusting of said second holding screw.
Among the present invention; On the supporting member hold down gag is installed under said; Said hold down gag comprises set screw, compresses bracing frame, compressing tablet; The said bracing frame that compresses is fixed on the said down supporting member, and said compressing tablet is connected and controls said compressing tablet and move up and down with the said bracing frame that compresses through set screw.
Adopt said structure, on the basis of existing bone electronics fatigue and damage experiment machine, this device is installed; Can accomplish 3 of live body mouse ulnas or four-point bending torture test, set up live body rat ulna micro-damage model, be used for micro-damage research; After 3 in live body bone or four-point bending form micro-damage in addition; Can dynamic observe a series of indexs through equipment such as uCT (minitype CT), ESEMs changes: form bone remodeling, osteocyte apoptosis etc. like the periosteum woven bone; Particularly observe and be used to treat the osteoporosis new drug more clinically (like parathyrotrophin; The micro-dynamic change of each stage of the diphosphonate preparation) micro-damage being repaired can be observed the pharmacology curative effect carefully comprehensively, and this will be in performance significant role aspect mechanism, early diagnosis and the curative effect assessment of inquiring into metabolic bone disease and fracture.
Description of drawings
Fig. 1 is a structural representation of the present invention.
Fig. 2 is the structural representation of side of the present invention.
Fig. 3 is the structural representation of Fig. 1 band bracing frame.
Accompanying drawing 1; 2; In 3: 1-upper connecting rod; Coupling shaft on 2-spring; 3-linear elasticity spring; Coupling shaft under 4-spring; 5-guide pillar; 6-linear bearing; 7-T type seaming chuck slide; 8-the first holding screw; 9-seaming chuck; 10-following supporting member; 11-loading dish; 12-guide rail; 13-C type lower slider; 14-spiral lifting mechanism; 15-lower connecting rod; 16-the second holding screw; 17-bracing frame; 18-chamber; 19-set screw; 20-compress bracing frame; 21-compressing tablet.
Embodiment
Below in conjunction with accompanying drawing, specify the embodiment of 3 of live body mouse ulnas or four-point bending fatigue test clamper.
Like Fig. 1, shown in 2, these anchor clamps mainly are made up of loading dish 11 and forelimb load testing machine two parts.Loading dish 11 adopts corrosion resistant high-quality stainless steel material to process, and long 30 centimetres, wide 20 centimetres, its effect is after loading anesthesia, with two rats that movable ligature is fixedly to be tested.Loading dish 11 can move up and down through the spiral lifting mechanism 14 that is installed in chamber 18 bottoms; Loading dish 11 bodies also can move forward and backward (anterior over against chamber) along the slide rail 12 that is installed in spiral lifting mechanism 14 tops in addition, the rat of applicable not of uniform size, various body weight.
The forelimb load testing machine comprises coupling shaft 2 on upper connecting rod 1, the spring, linear elasticity spring 3, four-point bending test apparatus main body and lower connecting rod 15.Coupling shaft 2 is processed by the fine aluminum alloy on the spring, and coupling shaft 2 adopts the open type clearance fit to be connected with upper connecting rod 1 on the spring, and convenient disassembly is saved test period, improves test efficiency.Coupling shaft 2 belows are connected with linear elasticity spring 3 on the spring, and linear elasticity spring 3 forms with Hooke's law and the test overall construction design that the external force that causes deformation is directly proportional according to the deformation of object in elastic limit.Used linear elasticity spring 3 maximum loads of this device are 100N, and in displacement control or power control procedure, the distortion and the test power that show in real time in the control survey system can be controlled a live body rat left side (right side) forelimb load.
The below of said T type seaming chuck slide 7 is provided with one or two seaming chuck 9; If a seaming chuck 9 only is set; This device is the three-point bending fatigue test clamper; If two seaming chucks 9 are set, this device is the four-point bending fatigue test clamper, and said seaming chuck 9 can be adjusted through first holding screw, 8 move left and right in T type seaming chuck slide 7 in the requirement according to correlation test; Tightening first holding screw 8 after adjusting can be fixing with seaming chuck 9; Following supporting member 10 also can be adjusted through second holding screw, 16 move left and right in C type lower slider 13 in the requirement according to correlation test, tightens second holding screw 16 after adjusting and will descend supporting member 10 fixing, and seaming chuck 9 is adjusted distance and done in T type seaming chuck slide 7
0-20mm, following supporting member 10 is adjusted distance and is done in C type lower slider 13
0-50mm, can solve a test live body rat left side (right side) forelimb problem different in size like this.Lower connecting rod 15 upper ends are connected with C type lower slider 13, and lower connecting rod 15 lower ends are connected with the load-sensing unit load sensor.Test load is through upper connecting rod 1; Coupling shaft 2 on the spring; Linear elasticity spring 3; Coupling shaft 4 is delivered on the seaming chuck 9 and a live body rat left side (right side) forelimb between the following supporting member 10 in the C type lower slider 13 that is placed in the T type seaming chuck slide 7 under the spring, and the load sensor that links to each other with lower connecting rod 15 is measured corresponding magnitude of load.
Among the present invention; Said hold down gag comprises set screw 19, compresses bracing frame 20, compressing tablet 21; The said bracing frame 20 that compresses is fixed on the said down supporting member 10, and said compressing tablet 21 is connected and controls said compressing tablet 21 and move up and down with the said bracing frame 20 that compresses through said set screw 19, through hold down gag; When the bigger mouse of build being cooked experiment, make a live body rat left side (right side) forelimb fixing more firm between seaming chuck and following supporting member.
Claims (1)
1. 3 of live body mouse ulnas or four-point bending fatigue test clamper; Comprise the loading dish (11) and the forelimb load testing machine that are installed in the chamber (18); It is characterized in that: said forelimb load testing machine comprises coupling shaft (4) under coupling shaft (2) on upper connecting rod (1), the spring, linear elasticity spring (3), the spring, T type seaming chuck slide (7), seaming chuck (9), following supporting member (10), C type lower slider (13), lower connecting rod (15); Said C type lower slider (13) is installed on the said lower connecting rod (15) that is connected with the main unit load sensor; The upper end of said C type lower slider (13) is provided with at least two guide pillars (5); The linear bearing (6) that said T type seaming chuck slide (7) ability is moved up and down along said guide pillar (5) is installed on the said T type seaming chuck slide (7); The top of said T type seaming chuck slide (7) is provided with coupling shaft (4) under the said spring that is connected with said linear elasticity spring (3) lower end; The upper end of said linear elasticity spring (3) is installed in the lower end of coupling shaft on the said spring (2); Coupling shaft on the said spring (2) is installed in the lower end of said upper connecting rod (1); The below of said T type seaming chuck slide (7) is provided with one or two seaming chuck (9), and the below that said C type lower slider (13) is gone up corresponding said seaming chuck (9) is provided with two following supporting members (10), and said loading dish (11) is installed in the said below of supporting member (10) down.
2. 3 of live body mouse ulnas according to claim 1 or four-point bending fatigue test clamper; It is characterized in that: the bracing frame (17) that supports loading dish (11) also is installed in the said chamber (18); The lower end of support frame as described above (17) is provided with stationary installation and is installed in the said chamber (18); The upper end of support frame as described above (17) is provided with spiral lifting mechanism (14); The top of said spiral lifting mechanism (14) is provided with slideway, and the lower end of said loading dish (11) is provided with the guide rail (12) that is installed in the said slideway.
3. 3 of live body mouse ulnas according to claim 1 and 2 or four-point bending fatigue test clamper; It is characterized in that: the below of said T type seaming chuck slide (7) laterally is provided with chute; Be provided with one or two seaming chuck (9) in the said chute, said seaming chuck (9) is fixed in the said chute through first holding screw (8) and said seaming chuck (9) can move at chute through the adjusting of said first holding screw (8).
4. 3 of live body mouse ulnas according to claim 1 and 2 or four-point bending fatigue test clamper; It is characterized in that: the below of said C type lower slider (13) laterally is provided with chute, and said two following supporting members (10) are fixed in the said chute through second holding screw (16) and said supporting member (10) down can move at chute through the adjusting of said second holding screw (16).
5. 3 of live body mouse ulnas according to claim 1 and 2 or four-point bending fatigue test clamper is characterized in that: on the supporting member (10) hold down gag is installed under said.
6. 3 of live body mouse ulnas according to claim 5 or four-point bending fatigue test clamper; It is characterized in that: said hold down gag comprises set screw (19), compresses bracing frame (20), compressing tablet (21); The said bracing frame (20) that compresses is fixed on the said down supporting member (10), and said compressing tablet (21) is connected and controls said compressing tablet (21) and move up and down with the said bracing frame (20) that compresses through said set screw (19).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011100604099A CN102183408B (en) | 2011-03-14 | 2011-03-14 | Three-point or four-point bending fatigue test fixture for living rat ulna |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011100604099A CN102183408B (en) | 2011-03-14 | 2011-03-14 | Three-point or four-point bending fatigue test fixture for living rat ulna |
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| Publication Number | Publication Date |
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| CN102183408A CN102183408A (en) | 2011-09-14 |
| CN102183408B true CN102183408B (en) | 2012-07-25 |
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| CN2011100604099A Expired - Fee Related CN102183408B (en) | 2011-03-14 | 2011-03-14 | Three-point or four-point bending fatigue test fixture for living rat ulna |
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| CN104007010B (en) * | 2014-05-20 | 2016-08-24 | 湖南大学 | A kind of horizontal impact formula injury biomechanics dynamic three point bending test device |
| CN107271271B (en) * | 2017-06-30 | 2019-07-12 | 东南大学 | A kind of ancillary test device being exclusively used in the research of small rod flexural property |
| CN108051317A (en) * | 2017-12-26 | 2018-05-18 | 安徽开诚电器有限公司 | A kind of bend testing apparatus of appliance switch element |
| CN107917844A (en) * | 2018-01-16 | 2018-04-17 | 天津工业大学 | A kind of 3 points of composite material, four-point bending fatigue universal test fixture |
| CN108717023B (en) * | 2018-07-17 | 2023-10-27 | 东北大学 | Device and method for simultaneously testing bending limit and resilience of magnesium alloy plate and strip |
| CN110006790A (en) * | 2019-04-09 | 2019-07-12 | 中国人民解放军总医院 | Cartilage permeability measurement apparatus and measurement method |
| CN110907297B (en) * | 2019-12-26 | 2021-03-26 | 北京航空航天大学 | Three-point bending fatigue test device applied to displacement loading |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6199508B1 (en) * | 1998-06-22 | 2001-03-13 | Theresa Miale | Animal lift and transport apparatus |
| CN2432890Y (en) * | 2000-07-28 | 2001-06-06 | 湖南医科大学附属第二医院 | Impact device for hone fatigue test |
| CN101158679A (en) * | 2007-11-23 | 2008-04-09 | 清华大学 | Extract and mechanical properties measurement method of bone trabecula and measurement mechanism |
| CN101637382A (en) * | 2008-07-28 | 2010-02-03 | 上海中医药大学附属曙光医院 | Vertebral rigidity measuring device for rat vertebral subluxation animal model |
| CN101694442A (en) * | 2009-10-20 | 2010-04-14 | 上海理工大学 | Mechanism for axially loading and clamping ulna of in-vivo experimental rat |
| US7784429B2 (en) * | 2006-09-22 | 2010-08-31 | Chiodo Chris D | Contoured specimen holder for imaging machines |
| CN201622205U (en) * | 2010-02-09 | 2010-11-03 | 上海理工大学 | Shin axial force-loading clamping mechanism for rats |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030111021A1 (en) * | 2001-12-13 | 2003-06-19 | Ru-Ping Lee | Animal experiment method |
-
2011
- 2011-03-14 CN CN2011100604099A patent/CN102183408B/en not_active Expired - Fee Related
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6199508B1 (en) * | 1998-06-22 | 2001-03-13 | Theresa Miale | Animal lift and transport apparatus |
| CN2432890Y (en) * | 2000-07-28 | 2001-06-06 | 湖南医科大学附属第二医院 | Impact device for hone fatigue test |
| US7784429B2 (en) * | 2006-09-22 | 2010-08-31 | Chiodo Chris D | Contoured specimen holder for imaging machines |
| CN101158679A (en) * | 2007-11-23 | 2008-04-09 | 清华大学 | Extract and mechanical properties measurement method of bone trabecula and measurement mechanism |
| CN101637382A (en) * | 2008-07-28 | 2010-02-03 | 上海中医药大学附属曙光医院 | Vertebral rigidity measuring device for rat vertebral subluxation animal model |
| CN101694442A (en) * | 2009-10-20 | 2010-04-14 | 上海理工大学 | Mechanism for axially loading and clamping ulna of in-vivo experimental rat |
| CN201622205U (en) * | 2010-02-09 | 2010-11-03 | 上海理工大学 | Shin axial force-loading clamping mechanism for rats |
Non-Patent Citations (1)
| Title |
|---|
| 戴如春等.SL_2000骨疲劳损伤实验机的研制与应用.《生物医学工程学杂志》.2006,第23卷(第1期),第192-195页. * |
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| CN102183408A (en) | 2011-09-14 |
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