CN102166149A - Antipyretic patch and preparation process thereof - Google Patents

Abstract

The invention discloses an antipyretic patch and a preparation process thereof. The antipyretic patch is comprises a non-woven fabric, a hydrogel layer and a plastic film, wherein the hydrogel layer comprises 0.3-1wt% of peppermint oil, 0.5-2% of polyvinyl pyrrolidone, 5-15% of glycerin, 0.1-0.5% of ethylenediamine tetraacetic acid, 0.005-0.01% of pigment and 75-90% of purified water by weight. The prepared hydrogel layer, the non-woven fabric and the film are coated and sheared on a hydrogel coating machine unit and dried for 24 hours until the water content reaches 65%; and thereby the cooling paste can be obtained by packaging. The cooling paste of the invention is a physical cooling product with a characteristic of relieving cold and fever symptoms.

Description

Defervescence plaster used and preparation technology

Technical field

The present invention relates to medical instruments field, be specifically related to defervescence plaster used and preparation technology.

Background technology

After the cat fever, medicines such as people's antibiotics commonly used are alleviated the fever symptom, and antibiotics can bring very large toxic and side effects to human body, and especially special population such as anemia of pregnant woman, baby more should not be taken antibiotics.

Summary of the invention

The object of the present invention is to provide a kind of employing Physical temperature-lowering, safe, the defervescence plaster used and preparation technology who has no side effect.

Defervescence plaster used, form by non-woven fabrics, hydrogel layer and plastic film, wherein, by weight percentage, hydrogel layer is made up of 0.3%～1% Oleum menthae, 0.5%～2% polyvinyl pyrrolidone, 5%～15% glycerol, 0.1%～0.5% disodiumedetate, 0.005%～0.01% pigment and 75%～90% purified water.

A kind ofly prepare described defervescence plaster used technology, concrete steps are:

1) it is standby Oleum menthae to be added in the ethanol mixing;

2) purified water is heated to 95 ℃, is incubated after 60 minutes, add glycerol, disodiumedetate;

3) through step 2) when mixture after handling is cooled to 45 ℃, add polyvinyl pyrrolidone, fully mix;

4) mixture that will be after step 1) is handled adds the mixture after step 3) is handled, and adds pigment, mixes, and promptly gets hydrogel layer;

5), on hydrogel coating unit, be coated with shearing with hydrogel layer, non-woven fabrics, plastic film;

6) will through step 5) shear defervescence plaster used drying in the air 24 hours, to water content be 65%, get final product defervescence plaster usedly.

Beneficial effect: of the present invention defervescence plaster used be aquogel system, with skin the extraordinary compatibility and safety are arranged.Walk heat by alcoholic acid volatile zone, and the refrigerant effect of Oleum menthae, alleviate the cat fever symptom, belong to the Physical temperature-lowering product.

With the defervescence plaster used head that spreads on of the present invention, safe, have no side effect, sustainable cooling is more than 8 hours.

The specific embodiment:

Embodiment 1

Of the present invention defervescence plaster used, form by non-woven fabrics, hydrogel layer and plastic film, by weight percentage, hydrogel layer is made by 0.5% Oleum menthae, 5% ethanol, 1% polyvinyl pyrrolidone, 10% glycerol, 1% disodiumedetate, 0.005% pigment and 83.395% purified water.

Defervescence plaster used preparation technology, concrete steps are:

1) mixing in the 5ml Oleum menthae adding 50ml ethanol is standby;

2) the 833.95m1 purified water is heated to 95 ℃, is incubated after 60 minutes, add 100ml glycerol, 10m1 disodiumedetate;

3) through step 2) when mixture after handling is cooled to 45 ℃, add the 10ml polyvinyl pyrrolidone, fully mix;

4) mixture that will be after step 1) is handled adds the mixture after step 3) is handled, and adds the 0.05ml pigment, mixes, and promptly gets hydrogel layer;

5), on hydrogel coating unit, be coated with shearing with hydrogel layer, non-woven fabrics, plastic film;

6) will through step 5) shear defervescence plaster used drying in the air 24 hours, to water content be 65%, can pack defervescence plaster usedly.

Claims (3)

1. defervescence plaster used, form by non-woven fabrics, hydrogel layer and plastic film, it is characterized in that, by weight percentage, described hydrogel layer is made up of 0.3%～1% Oleum menthae, 0.5%～2% polyvinyl pyrrolidone, 5%～15% glycerol, 0.1%～0.5% disodiumedetate, 0.005%～0.01% pigment and 75%～90% purified water.

2. according to claim 1 defervescence plaster used, it is characterized in that, in the prescription of described hydrogel layer, by weight percentage, Oleum menthae accounts for 0.5%, polyvinyl pyrrolidone accounts for 1%, glycerol accounts for 10%, disodiumedetate accounts for 0.1%, pigment account for 0.005% and purified water account for 88.395% and form.

3. one kind prepares defervescence plaster used technology as claimed in claim 1, it is characterized in that concrete steps are:

1) it is standby Oleum menthae to be added in the ethanol mixing;

2) purified water is heated to 95 ℃, is incubated after 60 minutes, add glycerol, disodiumedetate;

3) through step 2) when mixture after handling is cooled to 45 ℃, add polyvinyl pyrrolidone, fully mix;

4) mixture that will be after step 1) is handled adds the mixture after step 3) is handled, and adds pigment, mixes, and promptly gets hydrogel layer;

5), on hydrogel coating unit, be coated with shearing with hydrogel layer, non-woven fabrics, plastic film;

6) will through step 5) shear defervescence plaster used drying in the air 24 hours, to water content be 65%, get final product defervescence plaster usedly.