CN102090941A - Artificial iris with color change capability - Google Patents

Artificial iris with color change capability Download PDF

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Publication number
CN102090941A
CN102090941A CN2011100394546A CN201110039454A CN102090941A CN 102090941 A CN102090941 A CN 102090941A CN 2011100394546 A CN2011100394546 A CN 2011100394546A CN 201110039454 A CN201110039454 A CN 201110039454A CN 102090941 A CN102090941 A CN 102090941A
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China
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artificial iris
iris
artificial
photochromic
thickness
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CN2011100394546A
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Chinese (zh)
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CN102090941B (en
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郝燕生
肖真
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Wang Chong
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Abstract

The invention relates to an artificial iris with color change capability. The artificial iris comprises an artificial iris diaphragm and a photochromic shading layer, wherein the artificial iris diaphragm has a transparent disc structure, the center of which is provided with a hole, and pores are distributed on the artificial iris diaphragm; the photochromic shading layer is arranged in the artificial iris diaphragm, and the photochromic shading layer has a concentric ring structure; when the shading layer is irradiated by light, the photochromic substance in the shading layer changes color to reduce the transparency; and the thickness of the photochromic shading layer is distributed in a mode that the center is thin and the edge is thick, so that the photochromic capability (namely shading capability) of the shading layer is gradually enhanced together with the increment of the distance to the center. The artificial iris can be used for treating human eyes of eye traumas or pathological iridocoloboma, plays a role of a natural iris, and can regulate the pupil and the light transmission amount according to the illumination in the surrounding environment. The artificial iris with a fastening wire for fixing also solves the problem of high operation difficulty because the conventional artificial iris needs to be sutured at the eye.

Description

Artificial iris with metachrosis
Technical field
The present invention relates to a kind of artificial iris, specifically, relate to the artificial iris that a kind of usefulness has metachrosis.
Background technology
Pathological changes or wound may cause the atrophy of iris disappearance, and the control luminous energy power of eye and the effect of restriction aberration are disappeared, and visual function is in low state for a long time.Because the iris of atrophy disappearance can't make it regeneration by means such as medicines at present, so need to use the mode of operation to repair.Modus operandi commonly used has iris suture and artificial iris to implant.Iris suture is an elasticity of utilizing remaining normal iris tissue, with the iris tissue sutured together, plays the effect of certain control light and restriction aberration.Artificial iris is to utilize artificial material instead of part or whole iris.
The iris of human body self can change the size of iris central authorities pupil according to the illuminance generation muscular movement of surrounding owing to be subjected to neural control.And present artificial material can't realize adjusting according to illuminance the function of pupil or logical light quantity.
In addition, existing artificial iris normally is fixed on the remaining iris with suture way or in iris root or the ciliary groove.This mode needs to carry out the complicated suture and the operation of knotting in the space of narrow within the eye and sealing, and the difficulty of operation is big, has limited carrying out of this kind operation.Make the patient of numerous coloboma of iris can not get effective treatment.
Summary of the invention
The technical problem to be solved in the present invention provides a kind of artificial iris, and its inside comprises photochromic light shield layer, makes artificial iris adjust pupil and logical light quantity according to the illuminance in the surrounding.
For solving the problems of the technologies described above, artificial iris of the present invention comprise artificial iris every with photochromic light shield layer, wherein:
Described artificial iris is divided into central foraminous transparent disc shape structure, and artificial iris every on also be distributed with aperture;
Comprise photochromic light shield layer at described artificial iris every inside, photochromic light shield layer is the donut structure, but printed iris pattern, when being subjected to rayed, photochromic material in the light shield layer is understood variable color and is reduced transparency, the thickness of described photochromic light shield layer is the mode profile that central authorities are thin, the edge is thick, wherein the thickness near medium pore is 0.1-0.2mm, submarginal thickness is 0.2-0.3mm, thereby makes the photochromic function (being light shielding ability) of light shield layer increase and strengthen gradually with the distance at distance center;
Preferably, described artificial iris every outer circumference diameter be 8-12mm, gross thickness is 0.2-0.6mm, the aperture of medium pore is 3-5mm.
The current of buying a house in installments that act as of described aperture lead to, and preferred, the number of aperture is 1-3, and diameter is 0.2-0.25mm.
Preferably, also further be distributed with the crack on described artificial iris, operating theater instruments is conveniently used in acting as of this crack.More preferably, the number in described crack is 1-3, and length is 1.5-2.5mm.
As a kind of improvement of the present invention, described artificial iris can further include fixing with the button loop silk, and described fixing number with the button loop silk is greater than 1 and for centrosymmetry distributes, and in the filament portion that fastens with a rope, string, etc. the part of expanding is arranged.By button loop silk artificial iris is being carried out ophthalmic fixedly the time, the silk of will fastening with a rope, string, etc. penetrates scleral walls, with the elasticity of button loop silk and the part of expanding artificial iris is fixed on the scleral walls, thereby has avoided suture to fix this class complicated operation operation, and can be firm be fixed on the scleral walls.
Preferably, the number of described button loop silk is 3 or 4, and length is 5-7mm, and thickness is 0.3-0.5mm, and width is 0.4-0.6mm, and the top of described button loop silk is anti-slip T shape, zigzag, barb-like structure.
Describedly expand acting as of part and be stuck in the sclerotic puncture mouth and sentence and reach the fixed purpose of ophthalmic, preferably, described number of expanding part is 1-3, when expanding the number of part during greater than 1, can select a place to expand part according to the size of eyeball and fix.
Preferably, above-mentioned photochromic material include but not limited to triarylmethane, stilbene (Stilbene), azepine Stilbene, nitrone, fulgide (fulgides), spiro-pyrans, aphthopyrans, spiral shell-oxazines, 1 ', 3 '-dihydro-1 ', 3 ', 3 '-trimethyl-6-nitro spiral shell [2H-1-.alpha.-5:6-benzopyran-2,2 '-(2H)-indole], 1,3-dihydro-1,3,3-trimethyl-spiral shell [2H-indole-2,3 '-[3H] luxuriant and rich with fragrance [9,10-b] (1,4) oxazine].
Preferably, above-mentioned artificial iris includes but not limited to silica gel, polyethylene, PMMA (polymethyl methacrylate), acrylate etc. every using the button loop silk by any identical or different biocompatible materials with fixing.
Preferably, above-mentioned artificial iris is every, light shield layer and fixing one-body molded by casting film with the button loop silk, thereby do not need polishing punching to wait reworking, clean, encapsulation, can be after sterilizing for clinical use.
Artificial iris of the present invention can be used for treating the human eye of ocular injury or pathologic coloboma of iris, play the effect of natural iris, because the thickness of photochromic light shield layer is the mode profile that central authorities are thin, the edge is thick among the present invention, under different illumination conditions, the iris center is different with the transmittancy of periphery, thereby make the photochromic function (being light shielding ability) of light shield layer increase and strengthen gradually with the distance at distance center, therefore, the artificial iris of the present invention can also be adjusted pupil and logical light quantity according to the illuminance in the surrounding.
When artificial iris of the present invention is implanted in operation, can be fixed on the remaining iris or in iris root or the ciliary groove by suture way.As what implant is to have fixing artificial iris with the button loop silk, then can carry out ophthalmic by the button loop silk fixes, earlier artificial iris is curled after implantation device is implanted the anterior chamber, after treating that it launches naturally, be directed to outside the sclera with the entry needle silk of will fastening with a rope, string, etc. through the sclerotic puncture mouth, because button loop wire material elastical retraction selects the suitable part of expanding to be stuck in sclerotic puncture mouth place according to the needs of eyeball size, prune unnecessary button loop silk back and bury fixingly in the sclera flaggy, it is fixing not need additionally to sunken cord.
Description of drawings
Below in conjunction with the drawings and specific embodiments the present invention is described in more detail.
Fig. 1 is the plane graph of first kind of embodiment of the artificial iris of the present invention.
Fig. 2 is the profile of first kind of embodiment of the artificial iris of the present invention.
Fig. 3 is the plane graph of second kind of embodiment of the artificial iris of the present invention.
Fig. 4 is the profile of second kind of embodiment of the artificial iris of the present invention.
The specific embodiment
Embodiment 1
By artificial iris plane graph shown in Figure 1 and artificial iris profile shown in Figure 2 as can be known, artificial iris comprises that artificial iris is every 1 and photochromic light shield layer 8; Wherein artificial iris is the transparent disc shape structure of central authorities porose 3 every 1; Its outer circumference diameter is 11mm, and thickness is 0.4mm; The aperture of medium pore 3 is 4mm.Artificial iris every on also be distributed with 3 apertures 4, the diameter of each aperture 4 is 0.2mm.
Comprise photochromic light shield layer 8 at described artificial iris every 1 inside, photochromic light shield layer 8 is the donut structure of printed iris pattern, and the thickness of photochromic light shield layer is the mode profile that central authorities are thin, the edge is thick, wherein the thickness near medium pore is 0.1mm, and submarginal thickness is 0.2mm.
Embodiment 2
By artificial iris plane graph shown in Figure 3 and artificial iris profile shown in Figure 4 as can be known, artificial iris comprise artificial iris every 1, photochromic light shield layer 8 and fixing with button loop silk 2; Wherein artificial iris is the transparent disc shape structure of central authorities porose 3 every 1; Its outer circumference diameter is 10mm, and the thickness of close medium pore 3 is 0.3mm, and submarginal thickness is 0.5mm; The aperture of medium pore 3 is 3mm.Artificial iris every on also be distributed with 2 apertures 4, the diameter of each aperture 4 is 0.25mm, in addition, artificial iris every on crack 7 that also to be distributed with 2 length be 2mm.
Photochromic light shield layer 8 is the donut of printed iris pattern, is positioned at artificial iris and distributes ringwise every the central aperture periphery, and annular bandwidth is 3mm; And the thickness of photochromic light shield layer 8 is the mode profile that central authorities are thin, the edge is thick, and wherein the thickness near medium pore is 0.1mm, and submarginal thickness is 0.3mm.
Comprise photochromic light shield layer 8 at described artificial iris every 1 inside, photochromic light shield layer 8 is the donut structure of printed iris pattern, and the thickness of photochromic light shield layer is the mode profile that central authorities are thin, the edge is thick, wherein the thickness near medium pore is 0.2mm, and submarginal thickness is 0.3mm.
Fixing number with button loop silk 2 is 3, the distribution that is centrosymmetric, and each button loop filament length degree is 7mm, and thickness is 0.4mm, and width is 0.5mm, and on the button loop silk 3 equidistant parts 5 of expanding is arranged, and the top 6 of described button loop silk is anti-slip T shape structure.
When this artificial iris is implanted in operation, earlier artificial iris is curled after implantation device is implanted the anterior chamber, treat that it launches naturally after, will fasten with a rope, string, etc. with No. 25 entry needles thread is directed to outside the sclera of 10 points, 2 and 6 directions, and in the sclera flaggy, bury fixingly, it is fixing not need additionally to sunken cord.T shape plane can make the iris diaphragm plane consistent with former iris root ring plain effectively.

Claims (11)

1. artificial iris comprises that artificial iris is every (1) and photochromic light shield layer (8), wherein:
Described artificial iris be divided into central authorities porose (3) transparent disc shape structure, and artificial iris every on also be distributed with aperture (4);
Comprise photochromic light shield layer (8) at described artificial iris every (1) inside, photochromic light shield layer (8) is the donut structure, and its thickness is the mode profile that central authorities are thin, the edge is thick.
2. artificial iris according to claim 1, the thickness distribution of wherein said photochromic light shield layer (8) is 0.1-0.2mm for the thickness near medium pore, submarginal thickness is 0.2-0.3mm.
3. artificial iris according to claim 1, wherein said artificial iris is 8-12mm every the outer circumference diameter of (1), and thickness is 0.2-0.6mm, and the aperture of medium pore (3) is 3-5mm.
4. artificial iris according to claim 1, the number of wherein said aperture (4) are 1-3, and diameter is 0.2-0.25mm.
5. artificial iris according to claim 1, artificial iris every on also further be distributed with crack (7).
6. artificial iris according to claim 5, the number of wherein said crack (7) are 1-3, and length is 1.5-2.5mm.
7. according to each described artificial iris among the claim 1-6, it further comprises fixing with button loop silk (2), and described fixing number with button loop silk (2) is greater than 1 and for centrosymmetry distributes, and has in button loop filament portion and to expand partly (5).
8. artificial iris according to claim 7, the number of wherein said button loop silk (2) is 3 or 4.
9. artificial iris according to claim 8, the length of wherein said button loop silk (2) is 5-7mm, and thickness is 0.3-0.5mm, and width is 0.4-0.6mm; The top (6) of described button loop silk is T shape, zigzag or barb-like structure.
10. artificial iris according to claim 7, wherein said number of expanding part (5) is 1-3.
11. artificial iris according to claim 7, wherein said artificial iris every (1), photochromic light shield layer (8) and fixing be integrated with button loop thread (2) by casting film.
CN201110039454.6A 2011-02-17 2011-02-17 There is the artificial iris of metachrosis Expired - Fee Related CN102090941B (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2662054A1 (en) * 2012-05-07 2013-11-13 SNU R&DB Foundation Self-regulated artificial iris and method of fabricating the same
CN106264787A (en) * 2015-05-18 2017-01-04 爱博诺德(苏州)医疗器械有限公司 A kind of artificial iris fixing intraocular lens and material thereof and processing method
CN106466203A (en) * 2015-08-14 2017-03-01 爱博诺德(苏州)医疗器械有限公司 A kind of intraocular implant possessing stress deformation texture structure
US10888417B2 (en) 2016-04-22 2021-01-12 Obschestvo S Ogranichennoi Otvetstvennostyu Predpriyatie “Reper-Nn” Iris-lens diaphragm
US11648105B2 (en) 2016-05-17 2023-05-16 Humanoptics Holding Ag Ophthalmological implant

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2622179C1 (en) * 2016-04-22 2017-06-13 Общество с ограниченной ответственностью предприятие "Репер-НН" Artifical iris
CN106308977A (en) * 2016-08-31 2017-01-11 厦门大学附属厦门眼科中心 Artificial iris with a capsule

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1494879A (en) * 2002-09-24 2004-05-12 C Implant for changing iris color
EP1782763A1 (en) * 2005-11-04 2007-05-09 Dr. Schmidt Intraocularlinsen GmbH Iris fixated intraocular lens
US20070162117A1 (en) * 2003-05-07 2007-07-12 Heino Hermeking Iris prothesis system
US20090182423A1 (en) * 2008-01-16 2009-07-16 Lei Zheng Crystalline lens capsular support device for use in a surgical procedure on a human eye
CN101559009A (en) * 2009-05-25 2009-10-21 四川省医学科学院(四川省人民医院) Corneal contact lens with iris

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1494879A (en) * 2002-09-24 2004-05-12 C Implant for changing iris color
US20070162117A1 (en) * 2003-05-07 2007-07-12 Heino Hermeking Iris prothesis system
EP1782763A1 (en) * 2005-11-04 2007-05-09 Dr. Schmidt Intraocularlinsen GmbH Iris fixated intraocular lens
US20090182423A1 (en) * 2008-01-16 2009-07-16 Lei Zheng Crystalline lens capsular support device for use in a surgical procedure on a human eye
CN101559009A (en) * 2009-05-25 2009-10-21 四川省医学科学院(四川省人民医院) Corneal contact lens with iris

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2662054A1 (en) * 2012-05-07 2013-11-13 SNU R&DB Foundation Self-regulated artificial iris and method of fabricating the same
CN106264787A (en) * 2015-05-18 2017-01-04 爱博诺德(苏州)医疗器械有限公司 A kind of artificial iris fixing intraocular lens and material thereof and processing method
CN106264787B (en) * 2015-05-18 2021-07-06 爱博诺德(苏州)医疗器械有限公司 Artificial iris capable of fixing artificial lens and material and processing method thereof
CN106466203A (en) * 2015-08-14 2017-03-01 爱博诺德(苏州)医疗器械有限公司 A kind of intraocular implant possessing stress deformation texture structure
US10888417B2 (en) 2016-04-22 2021-01-12 Obschestvo S Ogranichennoi Otvetstvennostyu Predpriyatie “Reper-Nn” Iris-lens diaphragm
US11648105B2 (en) 2016-05-17 2023-05-16 Humanoptics Holding Ag Ophthalmological implant

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Address after: 66, 100091, building 301, building 100, Tai Zhuang, Beijing, Haidian District

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