CN101843949A - Antibacterial PTCA dilatation catheter - Google Patents
Antibacterial PTCA dilatation catheter Download PDFInfo
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- CN101843949A CN101843949A CN200910106169A CN200910106169A CN101843949A CN 101843949 A CN101843949 A CN 101843949A CN 200910106169 A CN200910106169 A CN 200910106169A CN 200910106169 A CN200910106169 A CN 200910106169A CN 101843949 A CN101843949 A CN 101843949A
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- powder
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- dilatation catheter
- ptca
- antibiotic
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Abstract
The invention relates to a dilatation catheter used for treatment, in particular to an antibacterial PTCA dilatation catheter which comprises a sacculus, a far-end tube body part, a near-end tube body part that are sequentially connected and communicated with each other. The antibacterial PTCA dilatation catheter is prepared by the steps of: mixing one, two or three in ciprofloxacin powder, rifampicin powder and metal tungsten powder according to a certain proportion; fully mixing the prepared antibacterial powder with plastic master batch for milling; and finally, precisely extruding and blow molding for shaping, wherein the antibacterial powder accounts for 1-50% of the total weight ratio of the dilatation catheter, and the plastic master batch is prepared by one in poly-fluorinated ethylene propylene, polyfluortetraethylene, polyvinyl chloride, polyethylene, polyurethane, fluoro-polymer and thermoplastic elastomer. The antibacterial PTCA dilatation catheter has simple production technique, realizes long-acting antibacterial function, and greatly improves the safety factor of operation.
Description
Technical field
The present invention relates to the foley's tube that interventional therapy is used, particularly a kind of antibacterial PTCA dilatation catheter.
Background technology
When carrying out the PTCA operation, the operator inserts a kind of special foley's tube by percutaneous puncture patient peripheral arterial and support reaches patient's coronary artery, expands narrow pathological changes part, discharges metal net shaped structure stand, and the PTCA foley's tube then shifts out external.But, owing to get involved the medical catheter its own particularity, it is in the process of treatment, tend to infect, cause various vascular inflammations, even cause other fatal complication owing to reasons such as antibacterial absorption cause, so for the conduit of getting involved human body, particularly insert the foley's tube in the blood vessel, its antibiotic property is very important, and it is directly connected to the success or failure of treatment.
Existing foley's tube does not make it possess good antibacterial properties; Perhaps, contain the material of antimicrobial component simply with the pattern of invasion coated on the inside and outside surface of conduit in order to reach antibiotic purpose.Certain like this effect with sterilization and bacteria growing inhibiting, obtain certain antibacterial effect, but intervene operation process, because unpredictable factor is more, or the difficulty of operation own is very big, this time that just needs the PTCA foley's tube to stop in vivo is long, and after the anti-biotic material coating and blood Long contact time of common PTCA foley's tube, antimicrbial power just begins to descend significantly, What is more the phenomenon of coating shedding occurs, this just makes that the antibiotic persistency of PTCA foley's tube is poor, causes its antibiotic purpose to realize, even may influence the realization of diagnosis and treatment purpose.Simultaneously, with pattern of invasion antibiotic paint is applied in the production method of the surfaces externally and internally of body, must extrudes at conduit, finish by other operation after the blow molding again, production efficiency is low, cost is high.
Summary of the invention
It is a kind of safe and reliable that main purpose of the present invention is to provide, anti-microbial property is strong, the simple antibacterial type conduit sheath of production technology, thereby stop in the interventional therapy process, to infect, cause various vascular inflammations owing to reasons such as antibacterial absorption cause, even the situation that causes other fatal complication takes place, and enhance productivity, reduce cost.
In order to achieve the above object, the technical solution used in the present invention is: a kind of antibacterial PTCA dilatation catheter comprises that a sacculus, a distal tube body are connected successively and are communicated with a proximal tube body.Antibacterial PTCA dilatation catheter is a kind of with ciprofloxacin powder, rifampicin powder and metal tungsten powder, or two or three medicament mix by a certain percentage, fully mix with plastic master batch again with this antibiotic powder that makes, carry out mixing after, precision is extruded, blow molding prepares.Wherein antibiotic powder accounts for 1%～50% of this foley's tube overall weight ratio, and described plastic master batch can be made with perfluoroethylene-propylene, politef, polrvinyl chloride, polyethylene, polyurethane, fluoropolymer polymer, a kind of of thermoplastic elastomer (TPE).
According to above technical scheme, the present invention has following advantage:
1. make that the PTCA foley's tube is extruded in precision, promptly possessed antibiotic property in the blow molding, technology is simple, has improved production efficiency significantly.
2. stop coating shedding, make it to possess good antibacterial performance, realized long acting antibiotic, promoted safety coefficient dramatically.
Description of drawings
Accompanying drawing is the structural representation of antibacterial PTCA dilatation catheter of the present invention, and wherein label 1 is the distal tube body, and label 2 is the proximal tube body, and label 3 is a sacculus.
The specific embodiment
Below in conjunction with embodiment the present invention is described in further detail:
Ciprofloxacin powder and rifampicin powder are mixed by 1: 1 weight ratio, and then fully mix, make antibiotic powder with metal tungsten powder.With 400 the gram antibiotic powder and 1600 the gram polrvinyl chloride fully mix, carry out mixing after, with mixture extrude, blow molding, make PTCA foley's tube with long acting antibiotic function.
Ciprofloxacin powder and rifampicin powder are mixed by 1: 2 weight ratio, and then fully mix, make antibiotic powder with metal tungsten powder.With 200 the gram antibiotic powder and 1800 the gram polyethylene fully mix, carry out mixing after, with mixture extrude, blow molding, make PTCA foley's tube with long acting antibiotic function.
Ciprofloxacin powder and rifampicin powder are mixed by 1: 3 weight ratio, and then fully mix, make antibiotic powder with metal tungsten powder.With 600 the gram antibiotic powder and 1400 the gram fluoropolymer polymer fully mix, carry out mixing after, with mixture extrude, blow molding, make PTCA foley's tube with long acting antibiotic function.
Embodiment 4
Ciprofloxacin powder and rifampicin powder are mixed by 1: 2 weight ratio, and then fully mix, make antibiotic powder with metal tungsten powder.With 800 the gram antibiotic powder and 1200 the gram thermoplastic elastomer (TPE)s fully mix, carry out mixing after, with mixture extrude, blow molding, make PTCA foley's tube with long acting antibiotic function.
It below only is concrete preparation example of the present invention; protection scope of the present invention is not constituted any limitation. in addition to the implementation; the present invention can also have other embodiments. and all employings are equal to the technology of replacement or equivalent transformation formation, all drop within the present invention's scope required for protection.
Claims (3)
1. antibacterial PTCA dilatation catheter, comprise that a sacculus, a distal tube body are connected successively and are communicated with a proximal tube body, it is characterized in that: use fluorine-containing anti-biotic material as basic material, by the antibacterial PTCA dilatation catheter that precision is extruded, blow molding is made with long acting antibiotic function.
2. according to the described PTCA foley's tube of claim 1, it is characterized in that: described fluorine-containing anti-biotic material is by carrying out mixing making with antibiotic powder and plastic master batch, and wherein antibiotic powder accounts for 1%～50% of overall weight.
3. according to the described PTCA foley's tube of claim 1, it is characterized in that: described antibiotic powder is a kind of with ciprofloxacin powder, rifampicin powder and metal tungsten powder, or two or three medicament mixed by a certain percentage pulverulent mixture, described plastic master batch is a kind of with perfluoroethylene-propylene, politef, polrvinyl chloride, polyethylene, polyurethane, fluoropolymer polymer, thermoplastic elastomer (TPE).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910106169A CN101843949A (en) | 2009-03-26 | 2009-03-26 | Antibacterial PTCA dilatation catheter |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910106169A CN101843949A (en) | 2009-03-26 | 2009-03-26 | Antibacterial PTCA dilatation catheter |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101843949A true CN101843949A (en) | 2010-09-29 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200910106169A Pending CN101843949A (en) | 2009-03-26 | 2009-03-26 | Antibacterial PTCA dilatation catheter |
Country Status (1)
| Country | Link |
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| CN (1) | CN101843949A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103391797A (en) * | 2011-01-17 | 2013-11-13 | 诺维塔治疗有限责任公司 | Detachable metal balloon delivery device and method |
| CN112774003A (en) * | 2021-01-28 | 2021-05-11 | 华中科技大学同济医学院附属协和医院 | Drainage anal canal device and preparation method of air bag I thereof |
| US11013516B2 (en) | 2011-01-17 | 2021-05-25 | Artio Medical, Inc. | Expandable body device and method of use |
| US11033275B2 (en) | 2014-09-17 | 2021-06-15 | Artio Medical, Inc. | Expandable body device and method of use |
| US11484318B2 (en) | 2011-01-17 | 2022-11-01 | Artio Medical, Inc. | Expandable body device and method of use |
-
2009
- 2009-03-26 CN CN200910106169A patent/CN101843949A/en active Pending
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103391797A (en) * | 2011-01-17 | 2013-11-13 | 诺维塔治疗有限责任公司 | Detachable metal balloon delivery device and method |
| US9572698B2 (en) | 2011-01-17 | 2017-02-21 | Metactive Medical, Inc. | Ballstent device and methods of use |
| US9572697B2 (en) | 2011-01-17 | 2017-02-21 | Metactive Medical, Inc. | Blockstent device and methods of use |
| US10537451B2 (en) | 2011-01-17 | 2020-01-21 | Metactive Medical, Inc. | Ballstent device and methods of use |
| US10543115B2 (en) | 2011-01-17 | 2020-01-28 | Metactive Medical, Inc. | Blockstent device and methods of use |
| US11013516B2 (en) | 2011-01-17 | 2021-05-25 | Artio Medical, Inc. | Expandable body device and method of use |
| US11090176B2 (en) | 2011-01-17 | 2021-08-17 | Artio Medical, Inc. | Detachable metal balloon delivery device and method |
| US11484318B2 (en) | 2011-01-17 | 2022-11-01 | Artio Medical, Inc. | Expandable body device and method of use |
| US11033275B2 (en) | 2014-09-17 | 2021-06-15 | Artio Medical, Inc. | Expandable body device and method of use |
| CN112774003A (en) * | 2021-01-28 | 2021-05-11 | 华中科技大学同济医学院附属协和医院 | Drainage anal canal device and preparation method of air bag I thereof |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20100929 |