CN101513550A - 用于药物输送及其它用途的速溶微穿孔器 - Google Patents
用于药物输送及其它用途的速溶微穿孔器 Download PDFInfo
- Publication number
- CN101513550A CN101513550A CNA2009100029511A CN200910002951A CN101513550A CN 101513550 A CN101513550 A CN 101513550A CN A2009100029511 A CNA2009100029511 A CN A2009100029511A CN 200910002951 A CN200910002951 A CN 200910002951A CN 101513550 A CN101513550 A CN 101513550A
- Authority
- CN
- China
- Prior art keywords
- array
- skin
- medicine
- micropunch
- perforator
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/20—Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
- A61B17/205—Vaccinating by means of needles or other puncturing devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/007—Injectors for solid bodies, e.g. suppositories
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
- A61B2017/00345—Micromachines, nanomachines, microsystems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
Abstract
Description
Claims (16)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/179,749 US6945952B2 (en) | 2002-06-25 | 2002-06-25 | Solid solution perforator for drug delivery and other applications |
US10/179,749 | 2002-06-25 | ||
US41106302P | 2002-09-16 | 2002-09-16 | |
US60/411,063 | 2002-09-16 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN03819714A Division CN100591386C (zh) | 2002-06-25 | 2003-06-19 | 用于药物输送及其它用途的速溶微穿孔器 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101513550A true CN101513550A (zh) | 2009-08-26 |
CN101513550B CN101513550B (zh) | 2012-09-12 |
Family
ID=32174341
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2009100029511A Expired - Fee Related CN101513550B (zh) | 2002-06-25 | 2003-06-19 | 用于药物输送及其它用途的速溶微穿孔器 |
Country Status (2)
Country | Link |
---|---|
US (3) | US6945952B2 (zh) |
CN (1) | CN101513550B (zh) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101756761B (zh) * | 2009-12-31 | 2011-06-01 | 武汉天地通生物工程有限公司 | 一种带有耦合剂的发热贴剂及其制备方法 |
CN103874518A (zh) * | 2011-10-12 | 2014-06-18 | 3M创新有限公司 | 一体化微针阵列递送系统 |
CN104955517A (zh) * | 2012-12-21 | 2015-09-30 | 久光制药株式会社 | 敷贴器 |
US10086183B2 (en) | 2013-11-05 | 2018-10-02 | Hisamitsu Pharmaceutical Co., Inc. | Applicator |
CN110639124A (zh) * | 2019-09-29 | 2020-01-03 | 青岛市市立医院 | 一种微针定点麻醉装置 |
CN110891646A (zh) * | 2017-05-17 | 2020-03-17 | 麻省理工学院 | 具有高api载量的组件 |
US10828480B2 (en) | 2015-09-02 | 2020-11-10 | Hisamitsu Pharmaceutical Co., Inc. | Applicator |
Families Citing this family (209)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7828827B2 (en) | 2002-05-24 | 2010-11-09 | Corium International, Inc. | Method of exfoliation of skin using closely-packed microstructures |
US7108681B2 (en) | 2000-10-16 | 2006-09-19 | Corium International, Inc. | Microstructures for delivering a composition cutaneously to skin |
US7431710B2 (en) | 2002-04-08 | 2008-10-07 | Glaukos Corporation | Ocular implants with anchors and methods thereof |
US20040087992A1 (en) * | 2002-08-09 | 2004-05-06 | Vladimir Gartstein | Microstructures for delivering a composition cutaneously to skin using rotatable structures |
GB0210397D0 (en) | 2002-05-07 | 2002-06-12 | Ferring Bv | Pharmaceutical formulations |
US6945952B2 (en) * | 2002-06-25 | 2005-09-20 | Theraject, Inc. | Solid solution perforator for drug delivery and other applications |
US8353861B2 (en) | 2003-09-18 | 2013-01-15 | Texmac, Inc. | Applicator for applying functional substances into human skin |
ES2377647T3 (es) * | 2003-10-31 | 2012-03-29 | Alza Corporation | Aplicador auto-actuado para ordenamiento de microproyecciones |
US8871224B2 (en) | 2003-12-09 | 2014-10-28 | Allergan, Inc. | Botulinum toxin therapy for skin disorders |
US8048423B2 (en) * | 2003-12-09 | 2011-11-01 | Allergan, Inc. | Botulinum toxin therapy for skin disorders |
GB0402131D0 (en) | 2004-01-30 | 2004-03-03 | Isis Innovation | Delivery method |
WO2005094526A2 (en) | 2004-03-24 | 2005-10-13 | Corium International, Inc. | Transdermal delivery device |
US20050220734A1 (en) * | 2004-04-02 | 2005-10-06 | Allergan, Inc. | Therapy for melanin related afflictions |
US8696619B2 (en) * | 2004-08-10 | 2014-04-15 | Robert P. Schnall | Drug delivery devices |
US7619007B2 (en) | 2004-11-23 | 2009-11-17 | Adamas Pharmaceuticals, Inc. | Method and composition for administering an NMDA receptor antagonist to a subject |
WO2006058059A2 (en) | 2004-11-23 | 2006-06-01 | Neuromolecular Pharmaceuticals, Inc. | Composition comprising a sustained release coating or matrix and an nmda receptor antagonist, method for administration such nmda antagonist to a subject |
BRPI0607017B8 (pt) * | 2005-04-06 | 2021-05-25 | Adamas Pharmaceuticals Inc | composição farmacêutica compreendendo memantina e donezepil, e seu uso para o tratamento de condições relacionadas ao snc |
GB0509863D0 (en) * | 2005-05-16 | 2005-06-22 | Cambridge Biostability Ltd | Apparatus for administrating substances into a body |
US8043250B2 (en) * | 2005-05-18 | 2011-10-25 | Nanomed Devices, Inc. | High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances |
US8048017B2 (en) * | 2005-05-18 | 2011-11-01 | Bai Xu | High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances |
CA2610885A1 (en) * | 2005-06-07 | 2006-12-14 | David R. Staskin | Injection guidance system and method |
TWI419717B (zh) * | 2005-06-17 | 2013-12-21 | Altea Therapeutics Corp | 滲透傳送系統及其使用方法 |
DK1940459T3 (da) * | 2005-09-06 | 2014-05-26 | Theraject Inc | Fast-opløsningsperforator indeholdende aktivstofpartikel og/eller aktivstof-adsorberede partikler |
US7846445B2 (en) * | 2005-09-27 | 2010-12-07 | Amunix Operating, Inc. | Methods for production of unstructured recombinant polymers and uses thereof |
JP2009509535A (ja) * | 2005-09-27 | 2009-03-12 | アムニクス, インコーポレイテッド | タンパク様薬剤およびその使用 |
US7855279B2 (en) | 2005-09-27 | 2010-12-21 | Amunix Operating, Inc. | Unstructured recombinant polymers and uses thereof |
US20090099031A1 (en) * | 2005-09-27 | 2009-04-16 | Stemmer Willem P | Genetic package and uses thereof |
US20070142781A1 (en) * | 2005-12-21 | 2007-06-21 | Sayre Chauncey B | Microinjector chip |
US7658728B2 (en) * | 2006-01-10 | 2010-02-09 | Yuzhakov Vadim V | Microneedle array, patch, and applicator for transdermal drug delivery |
US20070202186A1 (en) | 2006-02-22 | 2007-08-30 | Iscience Interventional Corporation | Apparatus and formulations for suprachoroidal drug delivery |
US8464712B2 (en) * | 2006-03-10 | 2013-06-18 | Dose One, Llc | Medication inhaler |
US8197435B2 (en) | 2006-05-02 | 2012-06-12 | Emory University | Methods and devices for drug delivery to ocular tissue using microneedle |
DE102006022554B4 (de) * | 2006-05-15 | 2014-12-04 | Roche Diagnostics Gmbh | Verfahren und Vorrichtung zum Stimulieren eines Gewebes für die subkutane Verabreichung von Wirkstoffen |
CN101074935B (zh) * | 2006-05-19 | 2011-03-23 | 清华大学 | 探测器阵列及设备 |
US20090182306A1 (en) * | 2006-07-21 | 2009-07-16 | Georgia Tech Research Corporation | Microneedle Devices and Methods of Drug Delivery or Fluid Withdrawal |
EP2062611A4 (en) * | 2006-08-18 | 2010-01-06 | Toppan Printing Co Ltd | MICRO NEEDLE AND MICRO NEEDLE STAMP |
US20080214987A1 (en) * | 2006-12-22 | 2008-09-04 | Nanomed Devices, Inc. | Microdevice And Method For Transdermal Delivery And Sampling Of Active Substances |
US10525246B2 (en) | 2006-12-22 | 2020-01-07 | Nanomed Skincare, Inc. | Microdevice and method for transdermal delivery and sampling of active substances |
CA2676221C (en) | 2007-01-22 | 2016-12-20 | Corium International, Inc. | Applicators for microneedles |
EP2146689B1 (en) | 2007-04-16 | 2020-08-12 | Corium, Inc. | Solvent-cast microneedle arrays containing active |
US8734440B2 (en) * | 2007-07-03 | 2014-05-27 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Magnetically guided catheter |
WO2009001591A1 (ja) * | 2007-06-26 | 2008-12-31 | Lintec Corporation | 経皮吸収型貼付剤 |
US8399410B2 (en) | 2007-08-06 | 2013-03-19 | Allergan, Inc. | Methods and devices for desmopressin drug delivery |
EP2185701A4 (en) * | 2007-08-15 | 2011-03-02 | Amunix Operating Inc | COMPOSITIONS AND METHODS FOR ENHANCING THE PRODUCTION OF RECOMBINANT POLYPEPTIDES |
US20090053673A1 (en) * | 2007-08-23 | 2009-02-26 | Zimmer, Inc. | Method for localized treatment of periodontal tissue |
CN101808588B (zh) * | 2007-09-28 | 2012-12-19 | 贝尔法斯特女王大学 | 递送装置及方法 |
GB0719577D0 (en) * | 2007-10-08 | 2007-11-14 | Kirby Andrew J | Microimplant devices and methods of making and use thereof |
WO2009048607A1 (en) | 2007-10-10 | 2009-04-16 | Corium International, Inc. | Vaccine delivery via microneedle arrays |
AU2008341030B2 (en) | 2007-12-24 | 2014-04-17 | Vaxxas Pty Limited | Coating method |
CA2749347C (en) | 2008-02-07 | 2018-03-27 | The University Of Queensland | Patch production |
US20100286045A1 (en) | 2008-05-21 | 2010-11-11 | Bjarke Mirner Klein | Methods comprising desmopressin |
AU2009249610B2 (en) * | 2008-05-21 | 2014-01-16 | Theraject, Inc. | Method of manufacturing solid solution perforator patches and uses thereof |
US11963995B2 (en) | 2008-05-21 | 2024-04-23 | Ferring B.V. | Methods comprising desmopressin |
PT2712622T (pt) | 2008-05-21 | 2016-10-13 | Ferring Bv | Desmopressina orodispersível para aumentar o período inicial de sono tranquilo |
US9387000B2 (en) | 2008-05-23 | 2016-07-12 | The University Of Queensland | Analyte detection using a needle projection patch |
WO2009147641A2 (en) * | 2008-06-06 | 2009-12-10 | Wockhardt Research Centre | A device and a system for delivery of biological material |
US20100094249A1 (en) * | 2008-10-09 | 2010-04-15 | Ty Caswell | Wound treatment apparatus and methods |
US9168364B2 (en) | 2008-11-04 | 2015-10-27 | Janisys Limited | Transfer device for transferring a substance between the device and a subject |
CA2760573A1 (en) * | 2008-12-22 | 2010-07-01 | The University Of Queensland | Patch production |
US8957021B2 (en) | 2009-02-03 | 2015-02-17 | Amunix Operating Inc. | Glucose-regulating polypeptides and methods of making and using same |
LT2393828T (lt) | 2009-02-03 | 2017-01-25 | Amunix Operating Inc. | Prailginti rekombinantiniai polipeptidai ir juos apimančios kompozicijos |
US9033898B2 (en) | 2010-06-23 | 2015-05-19 | Seventh Sense Biosystems, Inc. | Sampling devices and methods involving relatively little pain |
CN102405018B (zh) | 2009-03-02 | 2014-11-19 | 第七感生物系统有限公司 | 与血液取样相关联的技术和装置 |
US8545455B2 (en) * | 2009-03-30 | 2013-10-01 | University Of Rochester | Needle shield for injections |
WO2010124255A2 (en) | 2009-04-24 | 2010-10-28 | Corium International, Inc. | Methods for manufacturing microprojection arrays |
US20100286600A1 (en) * | 2009-05-08 | 2010-11-11 | Bommannan D Bommi | Transdermal patch device |
EP2429503A1 (en) * | 2009-05-13 | 2012-03-21 | Protein Delivery Solutions, LLC | Pharmaceutical system for trans-membrane delivery |
US10206813B2 (en) | 2009-05-18 | 2019-02-19 | Dose Medical Corporation | Implants with controlled drug delivery features and methods of using same |
JP5805634B2 (ja) | 2009-06-08 | 2015-11-04 | アムニクス オペレーティング インコーポレイテッド | 成長ホルモンポリペプチド並びにその作成及び使用方法 |
RU2508135C2 (ru) | 2009-07-31 | 2014-02-27 | 3М Инновейтив Пропертиз Компани | Матрица полых микроигл |
CA2772051C (en) | 2009-08-24 | 2020-08-18 | Amunix Operating Inc. | Coagulation factor ix compositions and methods of making and using same |
US9017310B2 (en) * | 2009-10-08 | 2015-04-28 | Palo Alto Research Center Incorporated | Transmucosal drug delivery device and method including microneedles |
US8882748B2 (en) | 2009-10-08 | 2014-11-11 | Palo Alto Research Center Incorporated | Transmucosal drug delivery device and method including chemical permeation enhancers |
US9014799B2 (en) * | 2009-10-08 | 2015-04-21 | Palo Alto Research Center Incorporated | Transmucosal drug delivery device and method including electrically-actuated permeation enhancement |
US8834423B2 (en) * | 2009-10-23 | 2014-09-16 | University of Pittsburgh—of the Commonwealth System of Higher Education | Dissolvable microneedle arrays for transdermal delivery to human skin |
WO2011069010A2 (en) | 2009-12-02 | 2011-06-09 | Adamas Pharmaceuticals, Inc. | Amantadine compositions and methods of use |
US8900181B2 (en) | 2009-12-18 | 2014-12-02 | Srgi Holdings, Llc | Skin treatment and drug delivery device |
WO2011094573A1 (en) | 2010-01-28 | 2011-08-04 | Seventh Sense Biosystems, Inc. | Monitoring or feedback systems and methods |
JP6327852B2 (ja) * | 2010-05-04 | 2018-05-23 | コリウム インターナショナル, インコーポレイテッド | 微小突起アレイを使用した副甲状腺ホルモンの経皮送達のための方法及びデバイス |
KR101909645B1 (ko) * | 2010-05-07 | 2018-10-18 | 더 제너럴 하스피탈 코포레이션 | 조직이식과 조직복제 방법 및 장치 |
KR20130081659A (ko) | 2010-06-01 | 2013-07-17 | 노파르티스 아게 | 인플루엔자 백신 항원의 농축 및 동결건조 |
KR20130109004A (ko) | 2010-06-01 | 2013-10-07 | 노파르티스 아게 | 동결건조하지 않는 인플루엔자 백신 항원의 농축 |
TWI578997B (zh) | 2010-06-04 | 2017-04-21 | 輝瑞疫苗有限責任公司 | 用於預防或治療菸鹼成癮之共軛體 |
WO2012006677A1 (en) | 2010-07-14 | 2012-01-19 | The University Of Queensland | Patch applying apparatus |
EP2593014B1 (en) | 2010-07-16 | 2015-11-04 | Seventh Sense Biosystems, Inc. | Low-pressure environment for fluid transfer devices |
US20130158482A1 (en) | 2010-07-26 | 2013-06-20 | Seventh Sense Biosystems, Inc. | Rapid delivery and/or receiving of fluids |
US20120039809A1 (en) | 2010-08-13 | 2012-02-16 | Seventh Sense Biosystems, Inc. | Systems and techniques for monitoring subjects |
US20120041338A1 (en) * | 2010-08-13 | 2012-02-16 | Seventh Sense Biosystems, Inc. | Clinical and/or consumer techniques and devices |
CA2808965C (en) | 2010-08-20 | 2020-01-07 | Novartis Ag | Soluble needle arrays for delivery of influenza vaccines |
EP3520749A1 (en) | 2010-10-15 | 2019-08-07 | Clearside Biomedical, Inc. | Device for ocular access |
CN103370007B (zh) | 2010-11-09 | 2018-12-18 | 第七感生物系统有限公司 | 用于采血的系统和界面 |
US10342574B2 (en) | 2010-12-17 | 2019-07-09 | Srgi Holdings, Llc | Pixel array medical devices and methods |
US10695546B2 (en) | 2010-12-17 | 2020-06-30 | Srgi Holdings, Llc | Systems, devices and methods for fractional resection, fractional skin grafting, fractional scar reduction and fractional tattoo removal |
US11103275B2 (en) | 2010-12-17 | 2021-08-31 | Srgi Holdings, Llc | Pixel array medical systems, devices and methods |
US10368904B2 (en) | 2013-12-06 | 2019-08-06 | Srgi Holdings, Llc | Pixel array medical systems, devices and methods |
US10736653B2 (en) | 2013-12-06 | 2020-08-11 | Srgi Holdings, Llc | Pixel array medical systems, devices and methods |
US11278309B2 (en) | 2010-12-17 | 2022-03-22 | Srgi Holdings, Llc | Pixel array medical systems, devices and methods |
US11000310B2 (en) | 2010-12-17 | 2021-05-11 | Srgi Holdings, Llc | Pixel array medical systems, devices and methods |
US10702684B2 (en) | 2010-12-17 | 2020-07-07 | Srgi Holdings, Llc | Systems, devices and methods for fractional resection, fractional skin grafting, fractional scar reduction and fractional tattoo removal |
US10661063B2 (en) | 2010-12-17 | 2020-05-26 | Srgi Holdings, Llc | Systems, devices and methods for fractional resection, fractional skin grafting, fractional scar reduction and fractional tattoo removal |
EP2654582B1 (en) | 2010-12-22 | 2017-05-31 | Valeritas, Inc. | Microneedle patch applicator |
AU2011200396B2 (en) * | 2011-01-31 | 2015-07-16 | Palo Alto Research Center Incorporated | lntralumenal or intravaginal device for Transmucosal drug delivery |
DK2673020T3 (da) | 2011-02-09 | 2017-11-20 | Sanofi Aventis Deutschland | Pen-injektionsanordning til to lægemidler med mikroreservoirer, der indeholder sekundært lægemiddel til nødinjektion |
CN102641549B (zh) * | 2011-02-18 | 2016-05-04 | 帕洛阿尔托研究中心公司 | 包括微针的透粘膜药物输送装置和方法 |
US8512679B2 (en) | 2011-03-04 | 2013-08-20 | Elwha Llc | Glassy compositions |
US20130281932A1 (en) * | 2011-03-30 | 2013-10-24 | Ziv Harish | Palm-based injector actuation and safety surfaces |
FR2973237A1 (fr) | 2011-03-31 | 2012-10-05 | Oreal | Procede de traitement cosmetique fractionne utilisant un laser ou des micro-aiguilles |
EP3235429B1 (en) | 2011-04-29 | 2023-06-07 | YourBio Health, Inc. | Devices and methods for collection of blood from a subject |
EP2701598A1 (en) | 2011-04-29 | 2014-03-05 | Seventh Sense Biosystems, Inc. | Systems and methods for collecting fluid from a subject |
US20130158468A1 (en) | 2011-12-19 | 2013-06-20 | Seventh Sense Biosystems, Inc. | Delivering and/or receiving material with respect to a subject surface |
BR112013027351B1 (pt) | 2011-04-29 | 2022-03-03 | Seventh Sense Biosystems, Inc | Dispositivo para receber fluido de um indivíduo |
GB201107642D0 (en) | 2011-05-09 | 2011-06-22 | Univ Cork | Method |
US10245178B1 (en) | 2011-06-07 | 2019-04-02 | Glaukos Corporation | Anterior chamber drug-eluting ocular implant |
US9498611B2 (en) | 2011-10-06 | 2016-11-22 | Hisamitsu Pharmaceutical Co., Inc. | Applicator |
US11179553B2 (en) | 2011-10-12 | 2021-11-23 | Vaxxas Pty Limited | Delivery device |
EP2766067B1 (en) * | 2011-10-12 | 2020-04-22 | 3M Innovative Properties Company | Integrated microneedle array delivery system |
AU2012328448B2 (en) * | 2011-10-28 | 2017-02-02 | Sung-Yun Kwon | Dissolving solid solution perforator patch for migraine treatment |
US20130192039A1 (en) * | 2012-01-31 | 2013-08-01 | Ronald Trusty | Sap cable tool remover for marine electronics sonar and power cables |
ES2935489T3 (es) | 2012-02-15 | 2023-03-07 | Bioverativ Therapeutics Inc | Composiciones de factor VIII y métodos de preparación y uso de las mismas |
KR102008190B1 (ko) | 2012-02-15 | 2019-08-07 | 바이오버라티브 테라퓨틱스 인크. | 재조합 인자 viii 단백질 |
KR20140143216A (ko) * | 2012-04-03 | 2014-12-15 | 테라젝트, 인코포레이티드 | 백신의 구강점막 전달용인 용해성 미세바늘 어레이 |
CA2871770C (en) | 2012-05-01 | 2020-07-07 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Tip-loaded microneedle arrays for transdermal insertion |
US9962535B2 (en) | 2012-05-11 | 2018-05-08 | 10X Technology Llc | Hollow silica glass microneedle arrays and method and apparatus for manufacturing same |
US9005108B2 (en) | 2012-09-27 | 2015-04-14 | Palo Alto Research Center Incorporated | Multiple reservoir drug delivery device and methods |
US9999720B2 (en) | 2012-09-27 | 2018-06-19 | Palo Alto Research Center Incorporated | Drug reconstitution and delivery device and methods |
US20140100530A1 (en) * | 2012-10-05 | 2014-04-10 | Miguel A. Linares | Attachable uterine device with integrated and time release medicinal administering component and insertion tool for implanting such a device |
CA2890471C (en) | 2012-11-08 | 2021-07-27 | Clearside Biomedical, Inc. | Methods and devices for the treatment of ocular diseases in human subjects |
EP2928395B1 (en) | 2012-12-06 | 2022-02-02 | SRGI Holdings LLC | Pixel array medical devices |
MX2015008157A (es) | 2012-12-21 | 2016-02-22 | Corium Int Inc | Microarreglo para la entrega de agente terapeutico y metodos de uso. |
US9744341B2 (en) | 2013-01-15 | 2017-08-29 | Palo Alto Research Center Incorporated | Devices and methods for intraluminal retention and drug delivery |
BR112015018014A2 (pt) | 2013-02-01 | 2017-07-11 | Glaxosmithkline Biologicals Sa | liberação intradérmica de composições imunológicas compreendendo agonistas do receptor do tipo toll |
BR112015019440A8 (pt) | 2013-02-20 | 2019-11-12 | Cytrellis Biosystems Inc | curativo regulável, kit, uso e método para fortalecimento da pele |
ES2921481T3 (es) * | 2013-03-12 | 2022-08-26 | Corium Inc | Aplicadores para microproyecciones |
EP2968118B1 (en) | 2013-03-15 | 2022-02-09 | Corium, Inc. | Microarray for delivery of therapeutic agent and methods of use |
EP4059450A1 (en) | 2013-03-15 | 2022-09-21 | Corium, Inc. | Microstructure array for delivery of active agents |
ES2761580T3 (es) | 2013-03-15 | 2020-05-20 | Corium Inc | Micromatrices para suministro de agente terapéutico, métodos de uso y métodos de fabricación |
CA2903763C (en) | 2013-03-15 | 2021-11-16 | Corium International, Inc. | Microarray with polymer-free microstructures, methods of making, and methods of use |
EP2968751B1 (en) * | 2013-03-15 | 2022-11-30 | Corium, Inc. | Multiple impact microprojection applicators |
SG10201702674PA (en) | 2013-05-03 | 2017-06-29 | Clearside Biomedical Inc | Apparatus and methods for ocular injection |
US20140350518A1 (en) | 2013-05-23 | 2014-11-27 | Allergan, Inc. | Syringe extrusion accessory |
US20140350516A1 (en) | 2013-05-23 | 2014-11-27 | Allergan, Inc. | Mechanical syringe accessory |
EP3003454B1 (en) | 2013-06-03 | 2020-01-08 | Clearside Biomedical, Inc. | Apparatus for drug delivery using multiple reservoirs |
US10154971B2 (en) | 2013-06-17 | 2018-12-18 | Adamas Pharma, Llc | Methods of administering amantadine |
WO2015005143A1 (ja) * | 2013-07-11 | 2015-01-15 | 凸版印刷株式会社 | マイクロニードルユニット |
AU2014293141A1 (en) | 2013-07-23 | 2016-02-18 | Serenity Pharmaceuticals Llc | Methods and compositions comprising desmopressin in combination with a beta-3 adrenergic receptor agonist |
AU2014293140A1 (en) | 2013-07-23 | 2016-03-03 | Serenity Pharmaceuticals Llc | Methods and compositions comprising desmopressin in combination with a 5-alpha reductase inhibitor |
US10548953B2 (en) | 2013-08-14 | 2020-02-04 | Bioverativ Therapeutics Inc. | Factor VIII-XTEN fusions and uses thereof |
CA2923010C (en) | 2013-09-03 | 2022-08-30 | Georgia Tech Research Corporation | Thermally stable vaccine formulations and microneedles |
RU2719927C2 (ru) | 2013-09-30 | 2020-04-23 | Джорджия Тек Рисёч Корпорейшн | Микроигольчатые пластыри, системы и способы |
AU2014329494B2 (en) | 2013-10-02 | 2019-06-20 | Edward Knowlton | Pixel array medical devices and methods |
ES2827049T3 (es) | 2013-10-02 | 2021-05-19 | Srgi Holdings Llc | Dispositivos médicos de conjunto de píxeles |
US11937846B2 (en) | 2013-12-06 | 2024-03-26 | Srgi Holdings Llc | Pixel array medical systems, devices and methods |
US20170296214A1 (en) | 2013-12-06 | 2017-10-19 | Edward KNOWLTON | Pixel array medical systems, devices and methods |
US11229452B2 (en) | 2013-12-06 | 2022-01-25 | Srgi Holdings, Llc | Pixel array medical systems, devices and methods |
US9297083B2 (en) | 2013-12-16 | 2016-03-29 | Palo Alto Research Center Incorporated | Electrolytic gas generating devices, actuators, and methods |
CA2981974C (en) | 2014-04-24 | 2023-06-20 | Georgia Tech Research Corporation | Microneedles and methods of manufacture thereof |
US10029048B2 (en) | 2014-05-13 | 2018-07-24 | Allergan, Inc. | High force injection devices |
EP3148491B1 (en) | 2014-05-29 | 2020-07-01 | Glaukos Corporation | Implants with controlled drug delivery features and manufacturing method for said implants |
CA2952958A1 (en) | 2014-06-20 | 2015-12-23 | Clearside Biomedical, Inc. | Variable diameter cannula and methods for controlling insertion depth for medicament delivery |
US9801660B2 (en) | 2014-07-31 | 2017-10-31 | Palo Alto Research Center Incorporated | Implantable fluid delivery devices, systems, and methods |
US10278675B2 (en) | 2014-07-31 | 2019-05-07 | Palo Alto Research Center Incorporated | Implantable estrus detection devices, systems, and methods |
EP3193828B8 (en) | 2014-08-29 | 2023-04-05 | Corium Pharma Solutions, Inc. | Microstructure array for delivery of active agents |
EP3188714A1 (en) | 2014-09-04 | 2017-07-12 | Corium International, Inc. | Microstructure array, methods of making, and methods of use |
US10226585B2 (en) | 2014-10-01 | 2019-03-12 | Allergan, Inc. | Devices for injection and dosing |
WO2018148214A2 (en) | 2014-10-02 | 2018-08-16 | Srgi Holdings, Llc | Pixel array medical systems, devices and methods |
USD750223S1 (en) | 2014-10-14 | 2016-02-23 | Clearside Biomedical, Inc. | Medical injector for ocular injection |
WO2016077759A1 (en) | 2014-11-14 | 2016-05-19 | Cytrellis Biosystems, Inc. | Devices and methods for ablation of the skin |
US10286033B2 (en) | 2014-11-20 | 2019-05-14 | Serenity Pharmaceuticals, Llc | Methods and compositions comprising desmopressin in combination with an alpha-adrenergic receptor antagonist |
CN104360499B (zh) * | 2014-11-26 | 2016-01-20 | 徐可欣 | 一种开车时瞌睡警示眼镜 |
WO2016123665A1 (en) | 2015-02-02 | 2016-08-11 | Vaxxas Pty Limited | Microprojection array applicator and method |
JP6805157B2 (ja) | 2015-02-05 | 2020-12-23 | エスアールジーアイ ホールディングス エルエルシーSrgi Holdings Llc | ピクセルアレイ医療システム、デバイスおよび方法 |
CN107530490B (zh) | 2015-03-10 | 2021-06-25 | 爱力根销售有限责任公司 | 多针注射器 |
US10441768B2 (en) | 2015-03-18 | 2019-10-15 | University of Pittsburgh—of the Commonwealth System of Higher Education | Bioactive components conjugated to substrates of microneedle arrays |
US10857093B2 (en) | 2015-06-29 | 2020-12-08 | Corium, Inc. | Microarray for delivery of therapeutic agent, methods of use, and methods of making |
EA201890423A1 (ru) | 2015-08-03 | 2018-07-31 | Биовератив Терапьютикс Инк. | Слитые белки фактора ix, способы их получения и применения |
US11751904B2 (en) | 2015-08-31 | 2023-09-12 | Srgi Holdings, Llc | Pixel array medical systems, devices and methods |
US11490952B2 (en) | 2015-08-31 | 2022-11-08 | Srgi Holdings, Llc | Pixel array medical devices and methods |
WO2017040853A1 (en) | 2015-09-02 | 2017-03-09 | Glaukos Corporation | Drug delivery implants with bi-directional delivery capacity |
WO2017045031A1 (en) | 2015-09-18 | 2017-03-23 | Vaxxas Pty Limited | Microprojection arrays with microprojections having large surface area profiles |
US11564833B2 (en) | 2015-09-25 | 2023-01-31 | Glaukos Corporation | Punctal implants with controlled drug delivery features and methods of using same |
US11684763B2 (en) | 2015-10-16 | 2023-06-27 | University of Pittsburgh—of the Commonwealth System of Higher Education | Multi-component bio-active drug delivery and controlled release to the skin by microneedle array devices |
US11744889B2 (en) | 2016-01-05 | 2023-09-05 | University of Pittsburgh—of the Commonwealth System of Higher Education | Skin microenvironment targeted delivery for promoting immune and other responses |
CA3010974A1 (en) | 2016-01-11 | 2017-07-20 | Verndari, Inc. | Microneedle compositions and methods of using same |
CN109069840B (zh) | 2016-02-04 | 2022-03-15 | 心脏起搏器股份公司 | 具有用于无引线心脏装置的力传感器的递送系统 |
US11564706B2 (en) | 2019-10-28 | 2023-01-31 | Srgi Holdings, Llc | Pixel array medical systems, devices and methods |
WO2017139375A1 (en) | 2016-02-10 | 2017-08-17 | Clearside Biomedical, Inc. | Ocular injection kit, packaging, and methods of use |
KR102288170B1 (ko) | 2016-04-08 | 2021-08-09 | 알레간 인코포레이티드 | 흡인 및 주입 디바이스 |
KR102194109B1 (ko) | 2016-04-15 | 2020-12-22 | 후지필름 가부시키가이샤 | 마이크로니들 어레이 |
CA3022830A1 (en) | 2016-04-20 | 2017-10-26 | Harold Alexander Heitzmann | Bioresorbable ocular drug delivery device |
JP2019514581A (ja) | 2016-05-02 | 2019-06-06 | クリアサイド バイオメディカル,インコーポレイテッド | 眼の薬物送達のためのシステムおよび方法 |
CN110177527B (zh) | 2016-08-12 | 2022-02-01 | 科尼尔赛德生物医学公司 | 用于调节药剂递送用针的插入深度的装置和方法 |
BR112019005312A2 (pt) | 2016-09-21 | 2019-07-16 | Cytrellis Biosystems Inc | dispositivos e métodos para a recomposição cosmética da pele |
RU2652567C1 (ru) * | 2016-11-08 | 2018-04-26 | Общество с ограниченной ответственностью "Микронидл Индастриал" | Микроигольный аппликатор и способ его изготовления |
USD867582S1 (en) | 2017-03-24 | 2019-11-19 | Allergan, Inc. | Syringe device |
JP6931217B2 (ja) | 2017-03-28 | 2021-09-01 | コスメディ製薬株式会社 | 水溶性シート状製剤のアプリケータ |
EP4306803A3 (en) | 2017-03-31 | 2024-04-10 | Vaxxas Pty Limited | Device and method for coating surfaces |
WO2018200885A1 (en) | 2017-04-26 | 2018-11-01 | Neurocentria, Inc. | Magnesium compositions and methods of use |
US11541015B2 (en) | 2017-05-17 | 2023-01-03 | Massachusetts Institute Of Technology | Self-righting systems, methods, and related components |
KR101976431B1 (ko) * | 2017-06-09 | 2019-05-10 | 주식회사 스몰랩 | 마이크로니들 탄성구조체 |
EP3639010A4 (en) | 2017-06-13 | 2021-03-17 | Vaxxas Pty Limited | QUALITY CONTROL OF SUBSTRATE COATINGS |
EP4218893A1 (en) | 2017-08-04 | 2023-08-02 | Vaxxas Pty Limited | Compact high mechanical energy storage and low trigger force actuator for the delivery of microprojection array patches (map) |
AU2019269636A1 (en) | 2018-05-17 | 2020-11-19 | Massachusetts Institute Of Technology | Systems for electrical stimulation |
WO2020005973A1 (en) | 2018-06-25 | 2020-01-02 | Corium, Inc. | Hybrid method of forming microstructure array molds, methods of making microstructure arrays, and methods of use |
US11633456B2 (en) | 2018-10-15 | 2023-04-25 | Augusta University Research Institute, Inc. | Compositions and methods for promoting hair growth |
WO2020110100A1 (en) * | 2018-11-29 | 2020-06-04 | Cannabidose Medical Ltd | Devices for topical delivery of active agents to a target site |
US11771829B2 (en) | 2019-02-01 | 2023-10-03 | Massachusetts Institute Of Technology | Systems and methods for liquid injection |
US11541216B2 (en) * | 2019-11-21 | 2023-01-03 | Massachusetts Institute Of Technology | Methods for manufacturing tissue interfacing components |
FR3122826A1 (fr) | 2021-05-12 | 2022-11-18 | L'oreal | Procedes et compositions pour l’amelioration de la peau |
FR3124952A1 (fr) | 2021-07-09 | 2023-01-13 | L'oreal | Procédés et compositions pour l’amélioration de la peau |
Family Cites Families (72)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3072122A (en) * | 1959-01-15 | 1963-01-08 | Rosenthal Sol Roy | Package for transcutaneous injection |
US3167073A (en) * | 1962-01-16 | 1965-01-26 | Rosenthal Sol Roy | Transcutaneous injection device |
US3596660A (en) * | 1969-05-12 | 1971-08-03 | Illinois Tool Works | Injection device |
US3964482A (en) | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
BE795384A (fr) * | 1972-02-14 | 1973-08-13 | Ici Ltd | Pansements |
DE2250293A1 (de) * | 1972-10-13 | 1974-04-25 | Bayern Freistaat | Impfstempel zur cutanen pockenimpfung mittels trockenimpfstoff |
OA05448A (fr) | 1975-10-16 | 1981-03-31 | Manufrance Manufacture Francai | Dispositif vaccinateur multipénétrant. |
US4966159A (en) * | 1981-12-14 | 1990-10-30 | Maganias Nicholas H | Allergy test strip |
IE53703B1 (en) | 1982-12-13 | 1989-01-18 | Elan Corp Plc | Drug delivery device |
US4798582A (en) | 1987-10-27 | 1989-01-17 | Permark Corp. C/O Sci/Med Advances Corp. | Needle cartridge |
US4936835A (en) | 1988-05-26 | 1990-06-26 | Haaga John R | Medical needle with bioabsorbable tip |
US5262128A (en) | 1989-10-23 | 1993-11-16 | The United States Of America As Represented By The Department Of Health And Human Services | Array-type multiple cell injector |
EP0429842B1 (en) | 1989-10-27 | 1996-08-28 | Korea Research Institute Of Chemical Technology | Device for the transdermal administration of protein or peptide drug |
US5527288A (en) | 1990-12-13 | 1996-06-18 | Elan Medical Technologies Limited | Intradermal drug delivery device and method for intradermal delivery of drugs |
TW279133B (zh) | 1990-12-13 | 1996-06-21 | Elan Med Tech | |
US5279544A (en) | 1990-12-13 | 1994-01-18 | Sil Medics Ltd. | Transdermal or interdermal drug delivery devices |
US5304220A (en) | 1991-07-03 | 1994-04-19 | Maginot Thomas J | Method and apparatus for implanting a graft prosthesis in the body of a patient |
US5455611A (en) * | 1992-05-29 | 1995-10-03 | Scitex Digital Printing, Inc. | Four inch print head assembly |
JP2599074Y2 (ja) * | 1992-10-09 | 1999-08-30 | 株式会社小森コーポレーション | 印刷機の水上り抑制装置 |
JP2587759Y2 (ja) * | 1992-10-29 | 1998-12-24 | ワイケイケイ株式会社 | 隠しスライドファスナーの開離嵌挿具 |
US5383512A (en) | 1993-01-27 | 1995-01-24 | Midwest Research Institute | Method for fabricating a substrate having spaced apart microcapillaries thereon |
US5749376A (en) * | 1993-10-18 | 1998-05-12 | Wilk; Peter J. | Medical treatment and waste disposal method |
US5445611A (en) | 1993-12-08 | 1995-08-29 | Non-Invasive Monitoring Company (Nimco) | Enhancement of transdermal delivery with ultrasound and chemical enhancers |
US5885211A (en) | 1993-11-15 | 1999-03-23 | Spectrix, Inc. | Microporation of human skin for monitoring the concentration of an analyte |
US5458140A (en) | 1993-11-15 | 1995-10-17 | Non-Invasive Monitoring Company (Nimco) | Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers |
US5457041A (en) | 1994-03-25 | 1995-10-10 | Science Applications International Corporation | Needle array and method of introducing biological substances into living cells using the needle array |
KR0134152B1 (ko) | 1994-05-23 | 1998-04-14 | 이형도 | 의약품 투여용 피부흠집 형성장치 |
US5591139A (en) | 1994-06-06 | 1997-01-07 | The Regents Of The University Of California | IC-processed microneedles |
US6290991B1 (en) | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
US6586006B2 (en) | 1994-08-04 | 2003-07-01 | Elan Drug Delivery Limited | Solid delivery systems for controlled release of molecules incorporated therein and methods of making same |
US6086196A (en) * | 1995-04-14 | 2000-07-11 | Sony Corporation | Printing device |
AU5740496A (en) | 1995-05-22 | 1996-12-11 | General Hospital Corporation, The | Micromechanical device and method for enhancing delivery of compounds through the skin |
DE19525607A1 (de) * | 1995-07-14 | 1997-01-16 | Boehringer Ingelheim Kg | Transcorneales Arzneimittelfreigabesystem |
US6013050A (en) | 1995-10-20 | 2000-01-11 | Powderject Research Limited | Particle delivery |
US5695484A (en) * | 1995-12-12 | 1997-12-09 | Cox; Brian J. | Anal patch for fecal incontinence |
CA2253549C (en) | 1996-06-18 | 2005-10-25 | Alza Corporation | Device for enhancing transdermal agent delivery or sampling |
EP0934093B1 (en) | 1996-09-17 | 2003-01-15 | Deka Products Limited Partnership | System for delivery of drugs by transport |
US5928207A (en) | 1997-06-30 | 1999-07-27 | The Regents Of The University Of California | Microneedle with isotropically etched tip, and method of fabricating such a device |
US20020009464A1 (en) | 1997-07-03 | 2002-01-24 | Camilo Colaco | Modified glycosides, compositions comprised thereof and methods of use thereof |
US6030404A (en) | 1997-09-06 | 2000-02-29 | Lawson; Alexis A. | Skin penetration apparatus including multiple needle configuration |
WO1999029364A1 (en) | 1997-12-11 | 1999-06-17 | Alza Corporation | Device for enhancing transdermal agent flux |
WO1999029298A2 (en) | 1997-12-11 | 1999-06-17 | Alza Corporation | Device for enhancing transdermal agent flux |
DK1037686T3 (da) | 1997-12-11 | 2006-01-02 | Alza Corp | Apparat til forögelse af transdermal gennemströmning af midler |
US6352722B1 (en) | 1997-12-23 | 2002-03-05 | Quadrant Holdings Cambridge Limited | Derivatized carbohydrates, compositions comprised thereof and methods of use thereof |
US5855211A (en) | 1998-02-17 | 1999-01-05 | Apollo Products, Inc. | Attachment unit for hair replacement |
US6106751A (en) | 1998-03-18 | 2000-08-22 | The Regents Of The University Of California | Method for fabricating needles via conformal deposition in two-piece molds |
US6091975A (en) | 1998-04-01 | 2000-07-18 | Alza Corporation | Minimally invasive detecting device |
US6503231B1 (en) * | 1998-06-10 | 2003-01-07 | Georgia Tech Research Corporation | Microneedle device for transport of molecules across tissue |
DE69939906D1 (de) | 1998-07-14 | 2008-12-24 | Altea Therapeutics Corp | Transdermale transportvorrichtung zum kontrollierten entfernen von biologischen membranen durch pyrotechnische ladung |
WO2000012173A1 (en) * | 1998-08-31 | 2000-03-09 | Johnson & Johnson Consumer Companies, Inc. | Electrotransport device comprising blades |
US6406455B1 (en) | 1998-12-18 | 2002-06-18 | Biovalve Technologies, Inc. | Injection devices |
US6485453B1 (en) | 1999-04-16 | 2002-11-26 | Novo Nordisk A/S | Cassette for storing and insertion of solid medicine |
US6743211B1 (en) * | 1999-11-23 | 2004-06-01 | Georgia Tech Research Corporation | Devices and methods for enhanced microneedle penetration of biological barriers |
US6611707B1 (en) * | 1999-06-04 | 2003-08-26 | Georgia Tech Research Corporation | Microneedle drug delivery device |
US6379324B1 (en) | 1999-06-09 | 2002-04-30 | The Procter & Gamble Company | Intracutaneous microneedle array apparatus |
US6256533B1 (en) | 1999-06-09 | 2001-07-03 | The Procter & Gamble Company | Apparatus and method for using an intracutaneous microneedle array |
US6312612B1 (en) | 1999-06-09 | 2001-11-06 | The Procter & Gamble Company | Apparatus and method for manufacturing an intracutaneous microneedle array |
US6102896A (en) | 1999-09-08 | 2000-08-15 | Cambridge Biostability Limited | Disposable injector device |
US6331266B1 (en) | 1999-09-29 | 2001-12-18 | Becton Dickinson And Company | Process of making a molded device |
US20020110585A1 (en) | 1999-11-30 | 2002-08-15 | Godbey Kristin J. | Patch therapeutic agent delivery device having texturized backing |
CA2396767A1 (en) | 1999-12-30 | 2001-07-12 | Redeon, Inc. | Stacked microneedle systems |
US6375776B1 (en) | 2000-01-24 | 2002-04-23 | Avery Dennison Corporation | Method for forming multi-layer laminates with microstructures |
US6603987B2 (en) | 2000-07-11 | 2003-08-05 | Bayer Corporation | Hollow microneedle patch |
US6440096B1 (en) * | 2000-07-14 | 2002-08-27 | Becton, Dickinson And Co. | Microdevice and method of manufacturing a microdevice |
US6656147B1 (en) * | 2000-07-17 | 2003-12-02 | Becton, Dickinson And Company | Method and delivery device for the transdermal administration of a substance |
GB0017999D0 (en) * | 2000-07-21 | 2000-09-13 | Smithkline Beecham Biolog | Novel device |
WO2002064193A2 (en) * | 2000-12-14 | 2002-08-22 | Georgia Tech Research Corporation | Microneedle devices and production thereof |
US6531206B2 (en) | 2001-02-07 | 2003-03-11 | 3M Innovative Properties Company | Microstructured surface film assembly for liquid acquisition and transport |
US20030135201A1 (en) * | 2001-09-28 | 2003-07-17 | Gonnelli Robert R. | Microneedle with membrane |
JP4090018B2 (ja) | 2002-02-18 | 2008-05-28 | For Head株式会社 | 機能性マイクロパイル及びその製造方法 |
US6945952B2 (en) * | 2002-06-25 | 2005-09-20 | Theraject, Inc. | Solid solution perforator for drug delivery and other applications |
US8353861B2 (en) * | 2003-09-18 | 2013-01-15 | Texmac, Inc. | Applicator for applying functional substances into human skin |
-
2002
- 2002-06-25 US US10/179,749 patent/US6945952B2/en not_active Expired - Lifetime
-
2003
- 2003-06-19 CN CN2009100029511A patent/CN101513550B/zh not_active Expired - Fee Related
-
2004
- 2004-01-28 US US10/767,359 patent/US7211062B2/en not_active Expired - Lifetime
-
2005
- 2005-11-21 US US11/285,669 patent/US7182747B2/en not_active Expired - Lifetime
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101756761B (zh) * | 2009-12-31 | 2011-06-01 | 武汉天地通生物工程有限公司 | 一种带有耦合剂的发热贴剂及其制备方法 |
CN103874518A (zh) * | 2011-10-12 | 2014-06-18 | 3M创新有限公司 | 一体化微针阵列递送系统 |
CN104955517A (zh) * | 2012-12-21 | 2015-09-30 | 久光制药株式会社 | 敷贴器 |
JPWO2014097837A1 (ja) * | 2012-12-21 | 2017-01-12 | 久光製薬株式会社 | アプリケータ |
US9913970B2 (en) | 2012-12-21 | 2018-03-13 | Hisamitsu Pharmaceutical Co., Ltd. | Applicator |
US10086183B2 (en) | 2013-11-05 | 2018-10-02 | Hisamitsu Pharmaceutical Co., Inc. | Applicator |
US10828480B2 (en) | 2015-09-02 | 2020-11-10 | Hisamitsu Pharmaceutical Co., Inc. | Applicator |
CN110891646A (zh) * | 2017-05-17 | 2020-03-17 | 麻省理工学院 | 具有高api载量的组件 |
CN110639124A (zh) * | 2019-09-29 | 2020-01-03 | 青岛市市立医院 | 一种微针定点麻醉装置 |
Also Published As
Publication number | Publication date |
---|---|
US7182747B2 (en) | 2007-02-27 |
US20040199103A1 (en) | 2004-10-07 |
US6945952B2 (en) | 2005-09-20 |
US7211062B2 (en) | 2007-05-01 |
US20040087893A1 (en) | 2004-05-06 |
CN101513550B (zh) | 2012-09-12 |
US20060074376A1 (en) | 2006-04-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN100591386C (zh) | 用于药物输送及其它用途的速溶微穿孔器 | |
CN101513550B (zh) | 用于药物输送及其它用途的速溶微穿孔器 | |
EP1940459B1 (en) | Solid solution perforator containing drug particle and/or drug-adsorbed particles | |
Garland et al. | Microneedle arrays as medical devices for enhanced transdermal drug delivery | |
CN101605536B (zh) | 用于活性物质透皮递送和取样的微器件和方法 | |
US10737081B2 (en) | Painless and patchless shooting microstructure | |
CN101553275A (zh) | 用于活性物质透皮递送和取样的高纵横比微器件和方法 | |
Bala et al. | Transdermal drug delivery system (TDDS)-a multifaceted approach for drug delivery | |
Sharma | Microneedles: an approach in transdermal drug delivery: a Review | |
Tabassum et al. | Microneedle technology: a new drug delivery system | |
Prausnitz et al. | Microneedles for drug delivery | |
Jain et al. | Transdermal Drug Delivery | |
Gujarathi et al. | Micro-and Nano-Systems in Transdermal Drug Delivery | |
Martin | Development, characterisation and evaluation of sugar glass microneedles |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
ASS | Succession or assignment of patent right |
Owner name: THERAJECT INC. Free format text: FORMER OWNER: QUAN SHENGRUN Effective date: 20120515 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20120515 Address after: California, USA Applicant after: THERAJECT, Inc. Address before: California, USA Applicant before: Quan Shengrun |
|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
EE01 | Entry into force of recordation of patent licensing contract |
Application publication date: 20090826 Assignee: B2Y Limited by Share Ltd. Assignor: THERAJECT, Inc. Contract record no.: 2013990000158 Denomination of invention: Solid solution perforator for drug delivery and other applications Granted publication date: 20120912 License type: Exclusive License Record date: 20130417 |
|
LICC | Enforcement, change and cancellation of record of contracts on the licence for exploitation of a patent or utility model | ||
CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120912 |