CN101004424B - Device and method for detecting jam of sample needle of biochemical analyser - Google Patents
Device and method for detecting jam of sample needle of biochemical analyser Download PDFInfo
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- CN101004424B CN101004424B CN2006100332835A CN200610033283A CN101004424B CN 101004424 B CN101004424 B CN 101004424B CN 2006100332835 A CN2006100332835 A CN 2006100332835A CN 200610033283 A CN200610033283 A CN 200610033283A CN 101004424 B CN101004424 B CN 101004424B
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Abstract
A device used for detecting out blocked specimen needle of biochemical analyzer is prepared for setting specimen needle to by variable impedance and variable capacity type, arranging liquid level detection circuit on detection circuit, switching specimen needle as variable impedance into liquid level detection circuit, detecting impedance variation of said variable impedance by liquid level detection circuit and outputting detected signal. The method utilizing said device to detect blocked specimen needle on biochemical analyzer is also disclosed.
Description
[technical field]
The present invention relates to sample needle of biochemical analyser and stop up pick-up unit and method.
[background technology]
For automatic clinical chemistry analyzer, the level detection pin is specimen needle particularly, stop up because of suction fibrin or haemocyte probably, cause application of sample inaccurate, even normal application of sample, this will have a strong impact on measurement result under the unwitting situation of operator, so necessary stopping state to specimen needle is judged.
For this reason, in patent US6,663, a kind of specimen needle clogging detecting system has been described in 353, comprise that two are detected transducing part, a part realizes level detection, thereby another part detects the situation of the variation judgement level detection pin of liquid paths internal pressure by pressure transducer.When specimen needle contact liquid level is prepared to inhale sample, liquid paths internal pressure situation can change suddenly, thereby produced a tangible saltus step, the unexpected variation that after inhaling the sample end, also will produce an internal pressure, force value is recovered, and like this, has just formed a pressure pulse, by pressure pulse signal is carried out complex calculations, and judge relatively with empirical value whether imbibition is normal.Because normal signal and improper signal pulsewidth are different, thus can judge abnormal duty thus, as specimen needle obstruction etc.
The above-mentioned method of whether stopping up with the pressure detection specimen needle is the effective way that solves the specimen needle judgment of clogging at present, and pressure detection also can realize the level detection function simultaneously.
But the method for pressure detection liquid level is subject to disturb, and therefore, in order to realize the level detection function reliably, can realize the judgment of clogging of level detection pin again, often needs two kinds of detection methods to be used, and structure is comparatively complicated.
[summary of the invention]
The object of the present invention is to provide a kind of sample needle of biochemical analyser to stop up pick-up unit and method, can easyly realize reliably stopping up detecting.
For achieving the above object, the sample needle of biochemical analyser that the present invention proposes stops up pick-up unit and comprises specimen needle, testing circuit, and it is characterized in that: described specimen needle is a variableimpedance; Described testing circuit comprises liquid level detection circuit; Described specimen needle is linked in the liquid level detection circuit as variableimpedance, and liquid level detection circuit detects the impedance variation of described variableimpedance, and detection signal is exported.
Preferably, this to install described variableimpedance be variable capacitance.
Preferably, this installs described variable capacitance is the double-layer coaxial structure, isolated with insulating material between internal layer and the skin, internal layer and outer respectively as two pole plates of variable capacitance.
Preferably, this installs described liquid level detection circuit and comprises oscillation source, instrument amplifier and balancing circuitry, the signal one tunnel that described oscillation source produced is input to the negative input end of instrument amplifier through first branch road of balancing circuitry, another road is input to the positive input terminal of instrument amplifier through second branch road of balancing circuitry, and specimen needle is inside and outside two-layerly to be linked in second branch road of balancing circuitry as two utmost points of variable capacitance respectively; Described balancing circuitry is set at when the capacitance of variable capacitance is particular value, it is input to the positive input terminal of instrument amplifier and the signal of negative input end keeps balance, when the capacitance of variable capacitance departed from particular value, it was input to the positive input terminal of instrument amplifier and the signal of negative input end produces difference.
Preferably, this device also comprises control panel, host computer, and described control panel one end links to each other with testing circuit, and the other end links to each other with host computer; Also include the A/D translation circuit, CPU, the interface circuit that link to each other successively in the described testing circuit, the input end of described A/D translation circuit links to each other with liquid level detection circuit, and the output terminal of described interface circuit links to each other with the input end of control panel.
Preferably, this installs and also includes temperature sensing circuit in the described testing circuit, and its output terminal links to each other with another input end of A/D translation circuit.
The present invention also comprises a kind of sample needle of biochemical analyser choke detecting method, it is characterized in that comprising the steps: A, specimen needle is linked in the liquid level detection circuit as variableimpedance; B, utilize testing circuit to detect the impedance variation of described variableimpedance, and detection signal is exported; C, according to output signal judgement sample pin whether stop up.
Preferably, the described variableimpedance of this method is a variable capacitance.
Preferably, the method that testing circuit detects the impedance variation of described variableimpedance among this method step B comprises the steps: B1, utilizes signal that oscillation source produces; B2, described signal one tunnel is input to the negative input end of instrument amplifier through first branch road of balancing circuitry, another road is input to the positive input terminal of instrument amplifier through second branch road of balancing circuitry; B3, instrument amplifier are exported detected signal; Wherein, specimen needle is inside and outside two-layerly is linked in second branch road of balancing circuitry as two utmost points of variable capacitance respectively; Described balancing circuitry is set at when the capacitance of variable capacitance is particular value, it is input to the positive input terminal of instrument amplifier and the signal of negative input end keeps balance, when the capacitance of variable capacitance departed from particular value, it was input to the positive input terminal of instrument amplifier and the signal of negative input end produces difference.
Preferably, this method also comprises the steps: the detection signal of output is input to A/D translation circuit, CPU, interface circuit, control panel, host computer successively after step B.
Preferably, this method is gone back the testing environment temperature in step B, and the environment temperature detected value is input to A/D translation circuit, CPU, interface circuit, control panel, host computer successively.
Preferably, this method operating voltage variable quantity that will cause because of obstruction is by following formula correction:
Wherein Vt is variableimpedance and variation of temperature rate, T1 is the original state environment temperature, liquid level detection circuit operating voltage when Va is original state, Vb is the liquid level detection circuit operating voltage after variableimpedance changes, the environment temperature of T2 during for the Vb that obtains by the temperature sensing circuit signal; When the operating voltage variable quantity greater than preset threshold then the judgement sample pin stop up.
Compared with prior art, the present invention has following advantage:
Because the present invention is linked into the impedance (be preferably electric capacity) of level detection pin as a broad sense in the testing circuit, testing circuit can calculate the size of current variable capacitance (pin electric capacity) by operating voltage, its variable capacitance (pin electric capacity) has bigger variation when level detection pin contact liquid level, simultaneously, operating voltage also can respective change, and judge according to the variation of variable capacitance (pin electric capacity) whether the level detection pin has touched liquid level, therefore, the present invention can utilize the electric capacity liquid level checking method can realize the level detection function reliably, simultaneously, no longer need liquid-way system is carried out any modification, do not need pressure transducer and treatment circuit.When the level detection pin has been stopped up by fibrin in the sample or haemocyte etc., its variable capacitance (pin electric capacity) also can significant change, cooperates the current environmental temperature value and can judge whether the level detection pin stops up.Therefore, when the present invention utilizes the method for electric capacity level detection to detect liquid level reliably, utilize the Changing Pattern of level detection pin self capacity, can easyly realize reliably stopping up detecting.
In conjunction with simple temperature sensing circuit, can make testing result more accurate.
[description of drawings]
Fig. 1 is an embodiment of the invention sample needle of biochemical analyser structural drawing;
Fig. 2 is the blocked synoptic diagram of embodiment of the invention sample needle of biochemical analyser;
Fig. 3 is an embodiment of the invention fluid level detection system synoptic diagram;
Fig. 4 is an embodiment of the invention liquid level detection circuit synoptic diagram;
Fig. 5 is that embodiment of the invention level detection variable capacitance (pin electric capacity) is with the variation of ambient temperature curve.
[embodiment]
Embodiment one
This programme is about detecting the method that specimen needle is stopped up, utilized specimen needle to stop up back variable capacitance (pin electric capacity) to have the rule of bigger variation, variable capacitance (pin electric capacity) rule, and the one-to-one relationship of variable capacitance (pin electric capacity) and operating voltage realizes that the obstruction of specimen needle detects with variation of ambient temperature.Wherein, we have adopted temperature sensing circuit to indicate Current Temperatures, so that can eliminate the influence to variable capacitance (pin electric capacity) that environment temperature causes.
See the structure of specimen needle 4 earlier, as shown in Figure 1, specimen needle 4 is the double-layer coaxial structure, isolated between internal layer 4a and the outer 4b with insulating material 4c, specimen needle 4 is linked in the liquid level detection circuit 5 as the variable capacitance of a broad sense, and internal layer 4a and outer 4b are respectively as the pole plate of two non-rules of variable capacitance (pin electric capacity).
According to the capacitor principle, the electric capacity of capacitor can be by electrode area S[m
2], between two-plate apart from t[m] and dielectric relative dielectric constant ε represent, promptly
Wherein, ε
0=8.85*10
-12F/M is a constant.
Because specimen needle 4 structures are fixing, ε in the formula (1) and t are also definite, so the electric capacity of specimen needle 4 is determined by electrode area S.Because of the relative dielectric constant ε of air is about 1, the relative dielectric constant ε of pure water is about 82, behind specimen needle 4 contact sample cups 10 samples 11 liquid levels, sudden change has taken place in a pole plate border of variable capacitance (pin electric capacity), can think that correspondingly sudden change has taken place electrode area S, so its variable capacitance (pin electric capacity) has unexpected increase behind the specimen needle 4 contact liquid levels.
The sample 11 that specimen needle 4 is drawn in the sample cup 10, may cause specimen needle 4 to stop up, as shown in Figure 2, in this case, 11 liquid levels are in the air even specimen needle 4 is left sample, because of the filling material of specimen needle 4 internal layer 4a changes, make the boundary condition of an electrode of variable capacitance (pin electric capacity) that change take place, variable capacitance (pin electric capacity) is equal to electrode area S change taken place, so can increase equally.
Describe in detail below and detect the apparatus and method that specimen needle is stopped up.
Detect specimen needle and stop up, must a fluid level detection system as shown in Figure 3, total system comprises specimen needle 4, testing circuit 1, control panel 2, host computer 3 (as PC) etc.Testing circuit 1 is the core that function realizes, it comprises liquid level detection circuit 5, temperature sensing circuit 6, A/D conversion 7, CPU 8, interface circuit 9 etc.
Liquid level detection circuit 5 can be converted into work at present voltage to sample variable capacitance (pin electric capacity) size, be that operating voltage and sample variable capacitance (pin electric capacity) are one to one, a kind of scheme of liquid level detection circuit 5 as shown in Figure 4, signal source Vin is divided into two input ends that two-way is input to instrument amplifier respectively, R1, C1 and R2, C2 and sample variable capacitance (pin electric capacity) Cp Compositional balance circuit, signal Vin is input to the negative input end V-of instrument amplifier through R1 and C1 (first branch road of balancing circuitry), signal Vin is through R2, C2 and variable capacitance (pin electric capacity) Cp (second branch road of balancing circuitry) is input to the positive input terminal V+ of instrument amplifier, specimen needle 4 is inside and outside two-layerly to be linked in the circuit as two utmost points of variable capacitance (pin electric capacity) Cp respectively, its ectomesoderm 4b ground connection, R3 is as the gain-adjusted resistance of instrument amplifier.Other labels are among Fig. 4: 51 are oscillation source, and 52 is instrument amplifier, and 53 is level-conversion circuit.Described balancing circuitry is set at when the capacitance of variable capacitance Cp is particular value, it is input to the positive input terminal V+ of instrument amplifier 52 and the signal of negative input end V-keeps balance, when the capacitance of variable capacitance Cp departed from particular value, it was input to the positive input terminal V+ of instrument amplifier 52 and the signal of negative input end V-produces difference.
When specimen needle contact liquid level makes variable capacitance (pin electric capacity) undergo mutation, cause that the instrument amplifier input end signal changes, thereby make output signal Vo also undergo mutation, and analog signal conversion is become digital signal by A/D sampling, be sent to CPU 8, through after the signal Processing, level detection signal 13 is exported to control panel 2 by interface circuit 9.
Among Fig. 3, temperature sensing circuit 6 can convert current environment temperature to the relevant voltage value, also is sent to CPU 8, just can access current ambient temperature value by CPU 8 computed in software.
Normal temperature as 25 ℃ under, be in some initial positions after specimen needle cleans up, do not contact with liquid level, as Biochemical Analyzer service sink top, adjust liquid level detection circuit 5, make operating voltage at a suitable level, be made as Va, and can calculate corresponding sample pin 4 capacitances.Behind the biochemical instruments long-play, may cause specimen needle 4 to stop up, after specimen needle 4 was stopped up, variable capacitance (pin electric capacity) obviously increased, correspondingly, operating voltage also can increase, be made as Vb, keep under 25 ℃ of constant situations, when Vb-Va is made as Δ V greater than some threshold values in environment temperature, CPU 8 just gives control panel 2 by interface circuit 9 output jam signals 14, and expression specimen needle 4 is blocked.
Control panel 2 receives after the jam signal that photos and sending messages notice host computer 3 (as PC) requires host computer 3 to stop up from man-machine interface notifying operation person specimen needle 4, and the operator just can take countermeasure thus, such as forcing flushing etc.Table 1 is concrete experimental data, specimen needle is drawn static placement behind a certain amount of serum sample, the simulation pin stops up process, in the simulated experiment one, variable capacitance (pin electric capacity) was respectively before and after specimen needle was stopped up: 25.21pF, 25.63pF, variable quantity is 0.42pF, and operating voltage is respectively before and after stopping up: 0.913V, 1.862V, variable quantity are 0.949V; In the simulated experiment two, variable capacitance (pin electric capacity) was respectively before and after specimen needle was stopped up: 25.86pF, 26.37pF, variable quantity are 0.51pF, and operating voltage is respectively before and after stopping up: 1.427V, 2.523V, variable quantity are 1.096V;
Table 1 specimen needle blocking experiment
| Voltage (V) before stopping up | Stop up back voltage (V) | Voltage variety (V) | Variable capacitance (pin electric capacity) (pF) before stopping up | Stop up back variable capacitance (pin electric capacity) (pF) | Capacitance change (pF) | |
| Simulated experiment one | 0.913 | 1.862 | 0.949 | 25.21 | 25.63 | 0.42 |
| Simulated experiment two | 1.427 | 2.523 | 1.096 | 25.86 | 26.37 | 0.51 |
This shows that variable capacitance (pin electric capacity) variable quantity and operating voltage variable quantity were all bigger before and after specimen needle was stopped up.
The front is mentioned and is required environment temperature to remain unchanged, this is because sample variable capacitance (pin electric capacity) size can change along with variation of ambient temperature, both linear approximate relationships, as shown in Figure 5, environment temperature rising variable capacitance (pin electric capacity) will increase, and rate of change is about 0.03pF/ ℃.Wherein, horizontal ordinate be environment temperature (℃), ordinate is variable capacitance (pin electric capacity) value (pF).Curve be labeled as environment temperature respectively 3 ℃, 5 ℃, 13 ℃, 24 ℃ with 35 ℃ of conditions under variable capacitance (pin electric capacity) value.
Corresponding relation according to operating voltage and sample variable capacitance (pin electric capacity), environment temperature raises will make that operating voltage also increases, can obtain operating voltage and variation of temperature rate according to sample variable capacitance (pin electric capacity) and variation of temperature rate, be made as Vt/ ℃.
Such as, under 25 ℃ of normal temperature, when specimen needle was in initial position, operating voltage was Va, after specimen needle was stopped up, it was Vb that operating voltage increases, if environment temperature has been elevated to 30 ℃, then operating voltage should be: Vb+ (30-25) * Vt.
Two kinds of erroneous judgements so just may appear, though a kind of be that specimen needle is not stopped up because the rising of environment temperature makes operating voltage increase,,, then will judge obstruction by accident such as having surpassed above-mentioned detection threshold Δ V when voltage increases to a certain degree; Another kind of situation is, though specimen needle has been stopped up, operating voltage has increased, and making operating voltage reduce again because environment temperature reduces, and this can make operating voltage change can not surpass detection threshold Δ V, can cause erroneous judgement too.
In this programme, utilize temperature sensing circuit 6 that current environment temperature respective value is input to CPU 8, solve the Temperature Influence problem by software processes.Suppose that specimen needle is in original state, promptly clean up and be positioned at service sink top, environment temperature is T1, and this moment, the liquid level detection circuit operating voltage was Va, when reasons such as specimen needle obstruction make sample variable capacitance (pin electric capacity) increase, operating voltage also raises and is Vb, and by the temperature sensing circuit signal obtain this moment environment temperature be T2, therefore, remove outside the ambient temperature effect, because of the operating voltage variable quantity that obstruction causes, represent with V, should be:
When V greater than Δ V, then the judgement sample pin stops up.
Its more embodiment
The foregoing description only is used for that the present invention will be described, and is not the restriction to protection scope of the present invention.Those skilled in the art can make the design of some accommodations under enlightenment of the present invention, all belong to protection scope of the present invention, for example:
It is anti-that specimen needle also can be designed to variable resistors such as variable inductance, variable resistor, also can be designed to variable reluctances such as magneto sensor, giant magnetoresistance, or the like; Correspondingly, liquid level detection circuit also can change inductance testing circuit, resistance detecting circuit, magnetic resistance testing circuit into, or the like, no longer enumerate.
Claims (12)
1. a sample needle of biochemical analyser stops up pick-up unit, comprises specimen needle (4), testing circuit (1), control panel (2), and described testing circuit has CPU (8), interface circuit (9), it is characterized in that: described specimen needle (4) is a variableimpedance; Described testing circuit (1) comprises liquid level detection circuit (5); Described specimen needle (4) is linked in the liquid level detection circuit (5) as variableimpedance, liquid level detection circuit (5) detects the impedance variation Vb-Va of described variableimpedance, and export detection signal to CPU (8), when the impedance variation Vb-Va of described variableimpedance is made as Δ V greater than some threshold values, CPU (8) just gives control panel (2) by interface circuit (9) output jam signal, and expression specimen needle (4) is blocked; Liquid level detection circuit operating voltage when wherein Va is original state, Vb is the postrun liquid level detection circuit operating voltage of Biochemical Analyzer.
2. sample needle of biochemical analyser as claimed in claim 1 stops up pick-up unit, and it is characterized in that: described variableimpedance is a variable capacitance.
3. sample needle of biochemical analyser as claimed in claim 2 stops up pick-up unit, it is characterized in that: described variable capacitance is the double-layer coaxial structure, isolated with insulating material (4c) between internal layer (4a) and outer (4b), internal layer (4a) and skin (4b) are respectively as two pole plates of variable capacitance.
4. stop up pick-up unit as claim 1 or 2 or 3 described sample needle of biochemical analyser, it is characterized in that: described liquid level detection circuit (5) comprises oscillation source (51), instrument amplifier (52) and balancing circuitry, signal (Vin) a tunnel that described oscillation source (51) is produced is input to the negative input end (V-) of instrument amplifier (52) through first branch road of balancing circuitry, another road is input to the positive input terminal (V+) of instrument amplifier through second branch road of balancing circuitry, and specimen needle (4) is inside and outside two-layerly to be linked in second branch road of balancing circuitry as two utmost points of variable capacitance (Cp) respectively; Described balancing circuitry is set at when the capacitance of variable capacitance (Cp) is particular value, it is input to the positive input terminal (V+) of instrument amplifier (52) and the signal of negative input end (V-) keeps balance, when the capacitance of variable capacitance (Cp) departed from particular value, it was input to the positive input terminal (V+) of instrument amplifier (52) and the signal of negative input end (V-) produces difference.
5. stop up pick-up unit as claim 1 or 2 or 3 described sample needle of biochemical analyser, it is characterized in that: also comprise host computer (3), described control panel (2) one ends link to each other with testing circuit (1), and the other end links to each other with host computer (3); Also include the A/D translation circuit (7) that links to each other successively in the described testing circuit (1), the input end of described A/D translation circuit (7) links to each other with liquid level detection circuit (5).
6. sample needle of biochemical analyser as claimed in claim 5 stops up pick-up unit, and it is characterized in that: also include temperature sensing circuit (6) in the described testing circuit (1), its output terminal links to each other with another input end of A/D translation circuit (7); Described temperature sensing circuit (6) detects the temperature variation of described specimen needle (4) environment of living in, and exports temperature signal to CPU (8);
CPU (8) will press following formula correction because of the operating voltage variable quantity (V) that obstruction causes:
Wherein Vt is variableimpedance operating voltage and variation of temperature rate, T1 is the original state environment temperature, liquid level detection circuit operating voltage when Va is original state, Vb is the postrun liquid level detection circuit operating voltage of Biochemical Analyzer, the environment temperature of T2 during for the Vb that obtains by the temperature sensing circuit signal;
When V greater than threshold value (Δ V) then the judgement sample pin stop up.
7. a sample needle of biochemical analyser choke detecting method is characterized in that comprising the steps:
A, specimen needle (4) is linked in the liquid level detection circuit (5) as variableimpedance;
B, utilize testing circuit (5) to detect the impedance variation Vb-Va of described variableimpedance, and detection signal is exported; Liquid level detection circuit operating voltage when wherein Va is original state, Vb is the postrun liquid level detection circuit operating voltage of Biochemical Analyzer;
Whether C, stop up according to the signal judgement sample pin of output: when the impedance variation Vb-Va of described variableimpedance is made as Δ V greater than some threshold values, the expression specimen needle is blocked.
8. sample needle of biochemical analyser choke detecting method as claimed in claim 7 is characterized in that: described variableimpedance is a variable capacitance.
9. as claim 7 or 8 described sample needle of biochemical analyser choke detecting methods, it is characterized in that the method for the impedance variation of the described variableimpedance of testing circuit among the step B (5) detection comprises the steps:
B1, utilize oscillation source (51) the signal that produces (Vin);
B2, described signal one tunnel is input to the negative input end (V-) of instrument amplifier (52) through first branch road of balancing circuitry, another road is input to the positive input terminal (V+) of instrument amplifier through second branch road of balancing circuitry;
B3, instrument amplifier are exported detected signal;
Wherein, specimen needle (4) is inside and outside two-layerly is linked in second branch road of balancing circuitry as two utmost points of variable capacitance (Cp) respectively; Described balancing circuitry is set at when the capacitance of variable capacitance (Cp) is particular value, it is input to the positive input terminal (V+) of instrument amplifier (52) and the signal of negative input end (V-) keeps balance, when the capacitance of variable capacitance (Cp) departed from particular value, it was input to the positive input terminal (V+) of instrument amplifier (52) and the signal of negative input end (V-) produces difference.
10. sample needle of biochemical analyser choke detecting method as claimed in claim 7 is characterized in that also comprising the steps: after step B
The detection signal of output is input to A/D translation circuit (7), CPU (8), interface circuit (9), control panel (2), host computer (3) successively.
11., it is characterized in that as claim 7 or 8 described sample needle of biochemical analyser choke detecting methods:
In step B, go back the testing environment temperature, and the environment temperature detected value is input to A/D translation circuit (7), CPU (8), interface circuit (9), control panel (2), host computer (3) successively.
12. sample needle of biochemical analyser choke detecting method as claimed in claim 11 is characterized in that:
The operating voltage variable quantity V that will cause because of obstruction is by following formula correction:
Wherein Vt is variableimpedance operating voltage and variation of temperature rate, T1 is the original state environment temperature, liquid level detection circuit operating voltage when Va is original state, Vb is the liquid level detection circuit operating voltage after variableimpedance changes, the environment temperature of T2 during for the Vb that obtains by the temperature sensing circuit signal;
When V greater than threshold value Δ V then the judgement sample pin stop up.
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| CN2006100332835A CN101004424B (en) | 2006-01-20 | 2006-01-20 | Device and method for detecting jam of sample needle of biochemical analyser |
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Cited By (1)
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| WO2014169575A1 (en) * | 2013-04-16 | 2014-10-23 | 深圳迈瑞生物医疗电子股份有限公司 | Liquid level detection method and device, and immunoassay analyzer |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5304347A (en) * | 1992-02-08 | 1994-04-19 | Boehringer Mannheim Gmbh | Liquid transfer device for an analysis unit |
| US5855951A (en) * | 1994-01-20 | 1999-01-05 | Tulip Memory Systems, Inc. | Method for making ceramic substrates for magnetic-recording media |
| US6663353B2 (en) * | 2000-02-29 | 2003-12-16 | Gen-Probe Incorporated | Fluid transfer system |
| CN1651921A (en) * | 2004-02-06 | 2005-08-10 | 株式会社日立高新技术 | Liquid dispensing apparatus, automatic analyser using same, and liquid surface detecting apparatus |
-
2006
- 2006-01-20 CN CN2006100332835A patent/CN101004424B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5304347A (en) * | 1992-02-08 | 1994-04-19 | Boehringer Mannheim Gmbh | Liquid transfer device for an analysis unit |
| US5855951A (en) * | 1994-01-20 | 1999-01-05 | Tulip Memory Systems, Inc. | Method for making ceramic substrates for magnetic-recording media |
| US6663353B2 (en) * | 2000-02-29 | 2003-12-16 | Gen-Probe Incorporated | Fluid transfer system |
| CN1651921A (en) * | 2004-02-06 | 2005-08-10 | 株式会社日立高新技术 | Liquid dispensing apparatus, automatic analyser using same, and liquid surface detecting apparatus |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014169575A1 (en) * | 2013-04-16 | 2014-10-23 | 深圳迈瑞生物医疗电子股份有限公司 | Liquid level detection method and device, and immunoassay analyzer |
| US9702749B2 (en) | 2013-04-16 | 2017-07-11 | Shenzhen Mindray Bio-Medical Electronics Co., Ltd. | Liquid surface detection method and device, and immunoassay analyzer |
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|---|---|
| CN101004424A (en) | 2007-07-25 |
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Application publication date: 20070725 Assignee: Shenzhen Mindray Animal Medical Technology Co.,Ltd. Assignor: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS Co.,Ltd. Contract record no.: X2022440020009 Denomination of invention: Biochemical analyzer sample needle blockage detection device and method Granted publication date: 20110427 License type: Common License Record date: 20220804 |