CN100589851C - Reagent feeder for inner ear round window membrane - Google Patents
Reagent feeder for inner ear round window membrane Download PDFInfo
- Publication number
- CN100589851C CN100589851C CN200610119102A CN200610119102A CN100589851C CN 100589851 C CN100589851 C CN 100589851C CN 200610119102 A CN200610119102 A CN 200610119102A CN 200610119102 A CN200610119102 A CN 200610119102A CN 100589851 C CN100589851 C CN 100589851C
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- China
- Prior art keywords
- round window
- window membrane
- duct
- head
- catheter shaft
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Abstract
The present invention relates to medical equipment technology, and is one inner ear round window membrane administration device for treating inner ear diseases. The administration device is one forked-head two cavity duct comprising one duct head, one duct body and one duct tail. The duct body is divided longitudinally into two cavities communicated separately to two forked branches of the duct head, and each of the two branches has one joint in the outlet for connection to syringe cylinder. The duct tail is expanded to form one medicine storing chamber communicated to two cavities in the ductbody, and has one round window membrane sucker in the end opening. One metal electrode inserted into the partition between two cavities has outer end extending beyond the head fork and spherical inner end inserted into the medicine storing chamber. One skin fixing ring is set in the outer wall of the duct body. The present invention is reliable, convenient and determined in healing effect.
Description
Technical field
The present invention relates to technical field of medical instruments, particularly a kind of reagent feeder for inner ear round window membrane through round window membrane drug treatment disease of inner ear.
Background technology
Disease of inner ear (phonosensitive nerve deafness, dizzy, tinnitus etc.) is hals,Nasen und Ohrenheilkunde commonly encountered diseases, frequently-occurring disease clinically.When being administered systemically with whole body, because the existence of internal ear blood-lost barrier, the absorption and the distribution of many medicines are subjected to significant limitation, and the medicine that really enters into internal ear is very little, and therapeutic effect is both imprecise also undesirable.Along with people dissect and physiopathologic further investigation the internal ear that comprises round window membrane, make that keeping a certain partial medicine effective concentration in a long time becomes possibility in recent years.To become at the partial main administering mode of internal ear through the round window membrane infiltration administration, because it is higher that this method keeps complete interior ear structure, safety, thereby might obtain better therapeutic to the treatment of disease of inner ear such as Meniere, burst sensorineural deafness, noise induced hearing loss and tinnitus that causes therefrom and spontaneous tinnitus.The sharpest edges of internal ear topical are to bring into play therapeutical effect and the less whole body that involves with higher drug level.
The round window membrane edge is thicker, and central gradual change is thin, and film protrudes slightly to the tympanic canal direction.Average thickness 70 μ m do not change with change of age.Main technique methods through the round window membrane administration has at present:
1. injection of tympanum method: advantage is easy and simple to handle.The patient adopts special posture to make and retains a period of time around REN through the medicinal liquid that auripuncture injects, and helps the infiltration of medicinal liquid.Shortcoming is that medicine runs off through pharyngotympanic tube easily, and the medication amount that the patient absorbed is not easy to estimate, also causes the otitis media and the perforation of ear drum easily, influences auditory rehabilitation, and if the occupy-place of REN bubble makes medicine can't contact round window membrane probably.
2. tympanum incision: make a kerf through tympanum, under microscope or ear endoscope, gelfoam or Fibrin Glue are placed the REN place, can make drug slow wherein penetrate into internal ear by dripping a medicine.This method medicine fixed point accurately.Only needing patient in timing oneself to drip medicine gets final product.Shortcoming is that medicine runs off through pharyngotympanic tube easily equally, causes the otitis media and the perforation of ear drum easily.
3. the little charge pump of implanted: do external auditory meatus tympanum flap when the little charge pump of implanted is implanted, microtubule is introduced tympanum, the tip places in the REN, microtubule links to each other with Micropump, medicine pumps into the REN district by Micropump by microtubule, medicine in little charge pump is crossed certain hour and can be lost efficacy, and medicinal liquid that can't the REN district is residual during rechallenge gets rid of, and has reduced contact round window membrane concentration medicine.
4. through the perforate of cochlea bone wall directly in the administration of perilymph tympanic canal, though the good method of can yet be regarded as in theory.But there are deficiencies such as internal ear infringement, infection in the technology relative complex, only uses in zoopery at present.
Summary of the invention
But the purpose of this invention is to provide a kind of easy to operate repetitively administered and can keep the fresh effective reagent feeder for inner ear round window membrane of affected part medicine.
The present invention is a jaw shape double channel catheter, is made up of head, body, afterbody three parts.The body longitudinal subdivision of conduit becomes two chambeies, communicates with two arms of head bifurcated respectively, and one for advancing the medicine arm, and another is the drug arm, and respectively there is a joint that is connected mutually with injector syringe in the exit of two arms.The afterbody bulging of conduit, inner chamber are drug storage chamber, and this chamber communicates with two chambeies of body.The tail end opening part is the round window membrane sucker, and this sucker size just in time can be covered in the REN periphery.During use the round window membrane sucker of afterbody is pasted on the periphery of REN with biogum, the opening part of drug storage chamber is by REN and round window membrane sealing, the syringe and the dovetail connector that advances the medicine arm of medicinal liquid will be filled, and medicinal liquid is injected into drug storage chamber, medicine can continue to be penetrated into internal ear by round window membrane in drug storage chamber.At interval behind the certain hour, be connected prop up the mouth of pipe in drug syringe with outmoded medicinal liquid sucking-off, inject fresh medicinal liquid by advancing the medicine arm again.According to doctor's advice frequency repetitively administered like this, the interior medicine of drug storage chamber is maintained in the valid density scope, be beneficial to treatment.
Be the variation of monitor therapy front and back auditory function at any time, can bury a metal electrode in the interval of body two pipes underground, this electrode outer end is stretched out by the catheter head crotch, so that be connected with potentiometer, the inner drug storage chamber that inserts, its end are spheroidal in case injure round window membrane when contacting with round window membrane.Can monitor auditory function with the potentiometer connection electrode during use.
Fix this administrator during for ease of use, on the body outer wall of conduit, establish a skin retainer ring.This ring can be in art be sutured in behind the ear on the skin with suture, can certainly be fixed with adhesive tape or other modes.
Description of drawings
Fig. 1 is the vertical section structure sketch map of reagent feeder for inner ear round window membrane of the present invention.
The specific embodiment
Now in conjunction with the accompanying drawings and embodiments, the present invention is described in detail.
The present invention is a jaw shape double channel catheter, is made up of head 1, body 2, afterbody 3 three parts.The body longitudinal subdivision of conduit becomes two chambeies, communicates with two arm 1-1 of head 1 bifurcated respectively, and one for advancing the medicine arm, and another is the drug arm, and respectively there is a joint 1-2 who is connected mutually with injector syringe in the exit of two arms.Afterbody 3 bulgings of conduit, inner chamber is a drug storage chamber, this chamber communicates with two chambeies of body 2.The tail end opening part is round window membrane sucker 3-1, and this sucker size just in time can be covered in the REN periphery.During use the round window membrane sucker 3-1 of afterbody 3 is pasted on the periphery of REN with biogum, the opening part of drug storage chamber is by REN and round window membrane sealing, between form an airtight lacuna that only communicates with the medicine-pouring pipe and the drug discharging tube of body 2, the syringe of medicinal liquid and the dovetail connector that advances the medicine arm of head 1 will be filled, and medicinal liquid is injected into the drug storage chamber of afterbody 3, medicine can continue to be penetrated into internal ear by round window membrane in drug storage chamber.At interval behind the certain hour, be connected prop up the mouth of pipe in drug syringe with outmoded medicinal liquid sucking-off, inject fresh medicinal liquid by advancing the medicine arm again.According to doctor's advice frequency repetitively administered like this, the interior medicine of drug storage chamber is maintained in the valid density scope, be beneficial to treatment.
Be the variation of monitor therapy front and back auditory function at any time, can in the interval of catheter shaft two pipes, bury a metal electrode 4 underground, this electrode outer end 4-1 is stretched out by the crotch of catheter head 1, so that be connected with potentiometer, inner 4-2 inserts drug storage chamber, and it is terminal spherical in shape in case injure round window membrane when contacting with round window membrane.Outer end 4-1 with potentiometer connection electrode 4 during use can monitor auditory function.
Fix this administrator during for ease of use, on the catheter shaft outer wall, establish a skin retainer ring 5.This ring can be in art be sutured in behind the ear on the skin with suture, can certainly be fixed with adhesive tape or other modes
According to different needs, the present invention can be designed to different models.
Embodiment 1 the present invention is a jaw shape double channel catheter, is made up of head 1, body 2, afterbody 3 three parts.Body 2 length of conduit are 40mm, and longitudinal subdivision becomes two chambeies, and internal diameter is 1mm; The length of two arm 1-1 of head 1 is 15mm, internal diameter is 1mm, outlet is complementary with medical 1ml syringe: afterbody 3 bulgings, length is 6mm, the widest part internal diameter is 4mm, the end openings place of afterbody 3 is round window membrane sucker 3-1, and hem width is 2mm, and the edge is soft and be coated with one deck biogum paster.
Claims (3)
1. reagent feeder for inner ear round window membrane, form by catheter head (1), catheter shaft (2) and afterbody (3) three parts, catheter shaft (2) longitudinal subdivision becomes two inner chambers, communicate with two arms (1-1) of catheter head (1) respectively, one for advancing the medicine arm, another is the drug arm, and respectively there is a joint that is connected mutually with injector syringe (1-2) in the exit of two arms; It is characterized in that afterbody (3) bulging, inner chamber is a drug storage chamber, and this chamber communicates with two inner chambers of catheter shaft (2), and tail end opening part periphery is round window membrane sucker (3-1).
2. by the described administrator of claim 1, it is characterized in that in the interval in catheter shaft two chambeies, burying underground a metal electrode (4), this electrode outer end (4-1) is stretched out by the crotch of catheter head (1), so that be connected with potentiometer, inner (4-2) inserts drug storage chamber, and be inner terminal spherical in shape in case injure round window membrane when contacting with round window membrane.
3. by claim 1 or 2 described administrators, it is characterized in that on the catheter shaft outer wall, establishing a skin retainer ring (5).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200610119102A CN100589851C (en) | 2006-12-05 | 2006-12-05 | Reagent feeder for inner ear round window membrane |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200610119102A CN100589851C (en) | 2006-12-05 | 2006-12-05 | Reagent feeder for inner ear round window membrane |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101032643A CN101032643A (en) | 2007-09-12 |
| CN100589851C true CN100589851C (en) | 2010-02-17 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200610119102A Expired - Fee Related CN100589851C (en) | 2006-12-05 | 2006-12-05 | Reagent feeder for inner ear round window membrane |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100589851C (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101168744B (en) * | 2007-10-09 | 2010-05-19 | 西安交通大学 | In vivo gene transduction device |
| AU2009305745B9 (en) * | 2008-10-15 | 2013-07-18 | Med-El Elektromedizinische Geraete Gmbh | Inner ear drug delivery device and method |
| CN101933828B (en) * | 2010-09-09 | 2011-12-07 | 宁波市鄞州千峰机械科技有限公司 | Negative-pressure auricular point bloodletting acupuncture-knife |
| CN102793606A (en) * | 2012-09-05 | 2012-11-28 | 普光新高（北京）技术开发有限公司 | Novel multi-pipeline device for trickling and irrigating ears |
| US9616207B2 (en) | 2014-06-26 | 2017-04-11 | Cochlear Limited | Treatment of the ear |
-
2006
- 2006-12-05 CN CN200610119102A patent/CN100589851C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN101032643A (en) | 2007-09-12 |
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20100217 Termination date: 20121205 |