CN100409822C - Device for electrosurgically destroying body tissue - Google Patents
Device for electrosurgically destroying body tissue Download PDFInfo
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- CN100409822C CN100409822C CNB038120747A CN03812074A CN100409822C CN 100409822 C CN100409822 C CN 100409822C CN B038120747 A CNB038120747 A CN B038120747A CN 03812074 A CN03812074 A CN 03812074A CN 100409822 C CN100409822 C CN 100409822C
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- impedance
- subarray
- high frequency
- bringing device
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B18/1477—Needle-like probes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00875—Resistance or impedance
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B2018/1405—Electrodes having a specific shape
- A61B2018/1425—Needle
- A61B2018/143—Needle multiple needles
Abstract
The invention refers to a exerting device which is used for exerting high frequency current to thermal destroy the body tissue. The application device has an electrode set (7) with at least 3 active electrodes (1-6) coupled to the body tissue; HF generator (17), which can electronic connect with a plurality of electrodes to generate high frequency voltage; measuring device, used for measuring the impedance of the body issue among a plurality of electrodes. In addition, the exerting device comprises selector device, used for selecting subset from the electrode assembly comprising at least two interacting electrodes according to the impedance determined. Practice the controlling devices like this: exerting high frequency voltage among the selected subset in order to make the high frequency current flow in a plurality of interacting electrodes through the body tissue.
Description
Technical field
The present invention relates to a kind of bringing device that high frequency electric carries out soma's thermmohardening that is used to apply.This bringing device comprises an electrod-array, and this electrod-array has at least three active electrodes (active electrode) that can insert soma.This bringing device also comprises: the high frequency maker, be used to produce high frequency voltage, and this high frequency maker switchably is connected with one or more electrode; And measuring device, be used to measure the soma's impedance between all or the selected active electrode.
Background technology
The electrosurgery sclerosis of pathological tissues (abbreviating tissue hereinafter as), particularly electric heating sclerosis is in the medical domain known method.This method is particularly useful for the treatment of organ tumor (particularly liver neoplasm).For hardening process, one or more electrode inserted treats in the hardened tissue (being tumor tissues), or with its next-door neighbour, and make alternating current between these a plurality of electrodes or an electrode and being fixed between the external neutral electrode flow through.If electric current flows through (also can be between a plurality of electrodes and one or more neutral electrode) between this electrode and this neutral electrode, then be referred to as the monopolar electrode structure.If opposite, flow through (in this case, in the tissue at least two electrodes must be arranged) between a plurality of electrodes of electric current in inserting tissue itself, then be referred to as dipolar configuration.If have electrode (alternating current flows through) in the tissue between these electrodes, then this structure be called multi-polar structure more than two.
Insert the electrode form of electrode needle normally in the tissue.They have the conducting circular cylinder bar, remove outside one or more stub area (be the so-called electrode zone of action, or abbreviate active electrode as), this conducting circular cylinder bar with respect to around organize electric insulation.On the contrary, active electrode conducts electricity with soma and is connected.Selectively, active electrode can have integrated heat sensor.In certain embodiments, can mechanically extend other active electrode, to enlarge the volume of the tissue that can treat at the end of bar.
In monopolar configuration, between active electrode and neutral electrode, induce electric current between perhaps a plurality of active electrodes by the high frequency maker.In the dipolar configuration of alternative, can cancel neutral electrode.In this case, make closing of circuit, in this respect, required active electrode mutually insulated ground can be arranged on the electrode needle with co-axial structure, perhaps be arranged on two independently on the electrode needle by another active electrode.
The ohmage (for the part of complex tissue impedance) of tissue makes the alternating current that applies by electrode be converted into Joule heat.Under the temperature between 50 ℃ to 100 ℃, large-scale degeneration takes place in body special (body-specific) albumen, and the result makes problematic tissue regions death.By high-density current, mainly heat, thereby can carry out the localized heat tumor destruction at these electrode zones at the active electrode place.
Mode with example in U.S. Patent No. 5630426 discloses a kind of hardened apparatus and method of pathological tissue electric heating that are used for.
The reliability of especially treating for therapeutic effect it is essential that generation is suitable for the heat damage zone of pathological tissue (being tumor tissues) scope most.
Summary of the invention
The purpose of this invention is to provide a kind of device, the electric heating sclerosis that is used to organize makes it possible to destroy reliably pathological tissue.
Begin the described the sort of device that is used to apply high frequency electric of part by this description and realize this purpose, this device has selector installation, this selector installation links to each other with measuring device, and is used for comprising from the electrod-array selection according to measured impedance the subarray of at least two active electrodes.This device that is used to apply high frequency electric also has control device, and this control device links to each other with this selector installation, and is used for high frequency voltage is imposed on the active electrode of selected subarray, so that high frequency electric flows through between active electrode by soma.
In preferred structure, this bringing device has following structure: high frequency maker, measuring device, selector installation and control device are combined in one or more housing, apply maker with formation, this applies maker and has the connecting pin that is used for electrode and feeder line thereof.Therefore can be optionally with electrode with apply maker and link to each other.
Whether this applies maker and preferably includes the connection detecting unit, and this connects detecting unit and links to each other with connecting pin, and be used for automatic detecting electrode and link to each other with connecting pin.This connects detecting unit and preferably links to each other with control unit.
Correspondingly, this control unit preferably has following structure: the electrode that connects to some extent all participate in electrotherapy, with within the predetermined time, apply high frequency voltage at least one time to the electrode that each connected by selector installation.
In an alternative arrangements, can provide a plurality of switches for applying maker, can optionally cut off to fixed electrode by these switches, high frequency voltage is not imposed on cut electrode in the above described manner.
Other dependent claims has illustrated better structure of the present invention.
The present invention is based on the following fact, i.e. the be arranged in generation of electrode in tumor is suitable for playing a crucial role aspect the destroyed area of tumor tissues most.In clinical practice, big relatively when treating the disorganize zone when handling, in tissue, insert a plurality of electrode needle usually simultaneously, to improve effect by the heat damage zone that single electrode produces by stack.In addition, in some applications, realize uniform heat damage zone by the multichannel temperature measurement.Yet facts have proved that this is not enough,, and can not consider to have the tissue characteristics of certain distance with the measuring position because it relates to measurement a little.The treatment that this needs repeatedly that is to say, does not reach in the tissue regions for the treatment of and destroys the required temperature of tumor tissues fully.Thereby, the puzzlement that patient can be recurred, and must not no longer inferiorly receive treatment.
The progress of hot disorganization is depended on to a great extent in tissue impedance.Particularly, along with the increase of the hardening of tissue, its ohmage increases, and impedance simultaneously also increases.Ultimate principle of the present invention is: compare with temperature, tissue impedance represents a volume information (volume information), and this volume information has intactly been described the tissue characteristics between two required measuring positions of impedance measurement.Therefore, according to the present invention, can will be used for optimum treatment control with the multipole variation that applies the impedance operator that structure combines.Be surprised to find that,, that is to say relating under the multipole situation about applying, make high frequency electric a plurality of active electrodes between under the situation about flowing through, the tissue impedance between each active electrode does not show consistent characteristic.On the contrary, each active electrode between tissue may change withered state (drying-out) into, in this case, this tissue has very high impedance, and organize this state that also do not reach between other electrode pair, thereby show lower impedance.This is relevant with clinical diagnosis (recognition), even utilize the some temperature survey, can not guarantee reliable considerable damage.Cause for example equally distributed blood vessel of right and wrong of the withered reason of soma's heterogeneous body, blood vessel produces the local cooling effect that limits, thereby has offset therapeutic effect.
In addition, similar with the situation of pure dipolar configuration under the situation of multiple electrode structure, can fully phase out neutral electrode.In this way, flowing of electric current still is limited in the target area, thereby no longer produces one pole and apply known secondary effect (secondaryeffect) in the pattern.
Measuring unit be preferably used for according to measured impedance obtain the ohmage between the active electrode (5,6) of the predetermined quantity of the subarray of connection electrode (19) to some extent.Preferably, for low value R (0-200 ohm), this is by being defined as ohmage or effect resistance R to realize in the scope according to square merchant who obtains of measured operating power and current measured.On the contrary, for high value R (about 4200 ohm), mainly by measured voltage square with simultaneously-measured power between the merchant determine ohmage or act on resistance R.The advantage of this alternative arrangements is to realize according to the crucial dependence to ohm tissue resistance of actual concern the control of cutting tissue (tissue ablation) power, and on the contrary, depend on the influence that being controlled at of measured impedance is subjected to variable reactance impedance (reactive impedance) element (for example, because line capacitance and line inductance) to a great extent.The purpose of determining effective ohmage is to use simple means to reduce the influence of electric resistance impedance counter electrode effect.
Bringing device according to the present invention is used to apply high frequency electric to carry out the thermmohardening of soma, and this bringing device comprises: electrod-array has at least three active electrodes that can insert soma; The high frequency maker is used to produce high frequency voltage, and this high frequency maker switchably is connected to one or more electrode; And measuring device, be used to measure the impedance or the ohmage of the tissue between the whole or selected active electrode.This bringing device also comprises selector installation, and this selector installation links to each other with measuring device, and is used for selecting to comprise from electrod-array according to measured impedance or ohmage the subarray of at least two active electrodes.Also comprise control device, this control device links to each other with selector installation, and is used for applying high frequency voltage to the active electrode of selected subarray, so that high frequency electric flows through between these active electrodes by soma.
In this case, term " subarray " is used to represent the arbitrary part that comprises at least two active electrodes of electrod-array, comprises the situation of entire electrode array as subarray of selecting.Because as impedance (particularly ohmage) expression of the volume information relevant measurement, so that impedance or effect resistance measurement are applicable in treating hardened tissue regions is definite in various degree hardened to the progress of hardening effect with tissue characteristics.Can apply high frequency voltage by selected active electrode, with the various tissue regions of the form of therapy of intended target to electrod-array.In this case, the selection of electrode (that is the formation of subarray) has been determined by treating the current path of sclerotic tissue.
In an embodiment of the present invention, selector installation has following structure: when once selecting to begin through the scheduled time in the past, carry out new impedance or effect resistance measurement operation and select the new subarray that comprises at least two active electrodes.
Only apply high frequency electric within the predetermined time, and select new subarray according to new impedance or effect resistance, mean and to check the progress of cure process with preset time at interval, and the progress that further applies Yu detected of high frequency electric is adapted.In this respect, this new selection can be selected and the previous different electrode subarray of subarray that uses, by the current path for the treatment of the variation in the sclerotic tissue hardened progress is reacted.Especially not to all evenly sclerosis of remaining sclerotic tissue, but carrying out under the hardened situation that this is preferred with different speed parts.In addition, by cycle of applying of restriction in chronological order, can avoid because of after applying tissue regions that high frequency electric causes being treated burnt (buming) for a long time.
In another structure of the present invention, in applying the process of high frequency electric, adopt the impedance or the effect resistance of measuring device measuring body tissue.Measured impedance or effect resistance value for example can be relevant with the reference value of measuring before electrothermal therapy begins.This structure has following advantage: can especially with respect to the impedance or the effect changes in resistance of reference value, detect hardened progress continuously according to impedance of organizing between the electrode or effect resistance measurement.Therefore, can determine to apply the persistent period of high frequency electric according to hardened progress by the electrode subarray.By measured impedance or effect resistance value are compared with the previous reference value of determining, make when determining to apply the persistent period, can consider to measured impedance or the effect resistance value harmful effect, this harmful effect is for example caused by the different interval between the different electrodes, or is caused by the different impedances relevant with different tissue regions to be treated that existed before the treatment beginning.
Preferably, selector installation is designed to make:, then select to comprise the new subarray of at least two active electrodes if the impedance of the soma between the active electrode of the predetermined quantity of subarray or effect resistance meet or exceed predetermined value.
The fact that meets or exceeds predetermined impedance or effect resistance value shows that sclerosis has proceeded to given degree.Can treat the sclerosis other parts so far that also do not have of sclerotic tissue subsequently and carry out cure process.This makes can avoid the unnecessary long patient's anxiety that applies the persistent period and cause thus.In addition, this also can avoid especially effectively owing at tissue regions after applying high frequency electric this tissue of burning for a long time.
Can make up the selection of the time of depending on and depend on the selection of impedance, thereby as long as through the scheduled time or reach predetermined impedance or predetermined effect resistance just carries out new selection.
In another structure of the present invention, selector installation is constructed so that: before selecting or reselecting the subarray that comprises at least two active electrodes, this selector installation make measuring device carry out with all possible active electrode between the impedance or the effect resistance relevant measurement of soma, and select the impedance between it or effect resistance is minimum or not above those electrodes of predetermined value as subarray.
In new selection,, can on purpose high frequency voltage be applied to those minimum tissue regions of sclerosis progress degree owing to selected the soma between it to show those active electrodes of lowest impedance or minimum effect resistance.
Useful progress according to bringing device of the present invention is, control device is constructed to make: applying the beginning of process, to impose on active electrode with the high frequency voltage that predetermined period changes, and the subarray that basis selects to comprise at least two active electrodes in time at the impedance or the ohmage of moment generation after a while in applying process.Applying the beginning of operation, wholely treating that impedance or effect resistance in the sclerotic tissue usually still are identical or roughly the same value.The local difference of impedance or effect resistance only produces during applying process, thereby selects only just meaningful during applying process with impedance or effect resistance corresponding electrode.
The useful progress of another of bringing device is that selector installation is designed to select at least three active electrodes as subarray, and control device is designed so that active electrode has been subjected to distinguishing phase shift each other the effect of the high frequency voltage of constant phase angle.The phase shift high frequency electric has improved the uniformity of the high frequency electric that applies in treating sclerotic tissue.
Preferably select three active electrodes as subarray, the phase angle is 120 degree.This makes and can use three-phase current to operate active electrode.
Preferably selector installation or control device are designed to make: selector installation or control device disconnect impedance or ohmage surpasses predetermined maximum value R
MaxSubarray or combination of electrodes.In the elementary volume, volume element (volume element) of correspondence, stop the hardening of tissue subsequently.
Additionally or alternatively, control device is used for peak power P to be carried
MaxReduce to scheduled volume, this peak power P
MaxBe to surpass less than R
MaxQualification impedance or predetermined by the subarray of selecting respectively when limiting ohmage.By this way, withered by merely making hardened substantially tissue, can prevent that selected electrode subarray is disconnected prematurely before sclerosis will finish.
Preferably, selector installation or control device are designed so that: selector installation or control device cut-out impedance or ohmage are less than predetermined minima R
MinSubarray or combination of electrodes.Can detect short circuit in this way, to prevent to jeopardize the patient.
Preferably, after the chooser array, the power initial adjustment that control device will be by the subarray transmission selected respectively is for lower, and within the predetermined time, with one or more stage or continuously power is increased to predetermined peak power P
MaxThis has been avoided " popcorn effect ", and this effect is meant when applying peak power suddenly, owing to possible steam bubble can not dissipate fast enough, so the pressure that produces makes tissue disruption or this electrode needle is broken away from suddenly.
In preferable configuration of the present invention, the active electrode or the selected electrode of bringing device is arranged on the electrode needle, this makes it possible in treating hardened tissue regions or treats around the hardened tissue regions these active electrodes are set accurately.
Electrode needle can be the form of bipolar electrode pin, that is, these electrode needle comprise the active electrode of two mutually insulateds respectively, and these two active electrodes can be subjected to the effect of high frequency voltage independently of each other.In this way, high frequency electric is flowed between different electrode needle but also high frequency electric is flowed along single electrode needle, this has increased the transmutability of current path, and has increased the quantity of the part of can hardening separately for the treatment of the sclerotic tissue zone thus.
By using multipole electrode needle (that is, have more than two active electrode electrode needle) can further increase the transmutability factor.
The useful progress of electrode needle is that they are insulated cover (enclosure) and surround, and can extend predetermined length from insulation sleeve, thereby can regulate the number of electrodes of multipole electrode needle by extension from cover or retraction electrode needle.
Electrode needle can have one or more fluid passage, is used for cooling or heat effect electrode or whole pin.Particularly, see gas and liquid as fluid.Can use heating or cooling to make the tissue temperature rising (that is the temperature model in the tissue (pattem)) that causes owing to high frequency electric become even.Also the fluid passage can be used for existing ordinary electrode pin, to realize the more uniform temperature pattern.
In a kind of structure, passage is characterised in that they lead to active electrode, and is used to provide cooling fluid.The place of the electric current density maximum of high frequency electric, the rising maximum of tissue temperature.Usually electric current density is in active electrode place maximum.Counter electrode cools off the temperature that can reduce with the tissue of electrode direct neighbor, and makes the temperature model in the tissue more even thus.
In one embodiment, this fluid is deionization liquid (deionised liquid).The heat conductivity of liquid is usually than the height of gas, but conduction usually, thereby need provide good electric insulation for passage.Use through deionization and nonconducting therefrom liquid and mean the electric insulation that can save passage basically.The deionizing degree of liquid is good more, and required scope and the expense of insulating is just correspondingly low more.
Description of drawings
Hereinafter pass through detailed embodiment, describe other features and advantages of the present invention in the mode of example with reference to accompanying drawing, in the accompanying drawings:
Fig. 1 is the circuit block diagram of expression assembly of the present invention;
Fig. 2 is the circuit block diagram of expression the present invention one alternative arrangements;
Fig. 3 a and Fig. 3 b are illustrated in the electrode needle of using according in the device of the present invention;
Fig. 4 a and Fig. 4 b have represented plane graph and the side view and the correlated current of the setting of electrode needle in the tissue in the mode of example; And
Fig. 5 a and Fig. 5 b have represented plane graph and the side view and the correlated current of another setting of electrode needle in the tissue in the mode of example.
The specific embodiment
Fig. 1 is the circuit block diagram according to the embodiment of the by way of example of the device that is used for sclerosing of body tissues of the present invention.This device comprises a plurality of active electrodes 1 to 6, and these active electrodes form electrod-array 7 together.The separate lines 9 that electrode 1 to 6 passes through separately respectively links to each other with control unit 11.What link to each other with control unit 11 also has: measuring device 13 is used for the impedance of the tissue between the measurement electrode 1 to 6 or acts on resistance; Selector installation 15 is used to select electrode; And high frequency maker 17, be used to produce high-frequency ac voltage.
Under multipolar situation, high frequency maker 17 for example has the Ω at 20-50, and operating frequency is the 250W output under the 470kHz condition.Under bipolar situation, output for example is that operating frequency is similarly the 125W under the 470kHz condition at 100 Ω.The working range of high frequency maker is between 10 to 1000 Ω.Impedance or the effect resistance measurement undertaken by measuring device 13 can realize down at operating frequency or other frequency, the especially low frequency (for example 20kHz) of 470kHz.With the high frequency Generator Design is to be suitable for the typical application time of working under full load 20 minutes or longer time.
For when determining structural state, can consider the frequency dependence of impedance, can carry out impedance measurement with multiple frequency.For example determine to apply high frequency electric apply parameter the time, can consider to be included in the information in the frequency dependence of impedance.
In the present embodiment, all possible electrode pair of counter electrode array 7 carries out described impedance measurement operation so that selector installation 15 can obtain per two respective electrode between the resistance value of all tissue regions.Then, based on these resistance values, selector installation 15 is selected at least two electrodes of electrod-array 7, and these at least two electrodes constitute the subarray of electrod-array 7.
When the electrode 5 and 6 to subarray 19 applied high frequency voltage, high-frequency ac current flow through between electrode 5 and 6, caused tissue temperature to raise, and the result makes tissue degeneratiaon.At preset time after the cycle, control unit 11 stops providing high frequency voltage to the electrode of subarray 19, and makes measuring device 13 impedance between the possible electrode pair of institute of array of measure electrodes 7 once more.Selector installation 15 is for example selected the impedance of organizing between it subsequently and is raise minimum electrode pair as subarray 19 from electrod-array.Can also use different weighter factors that resistance value is weighted.Selected electrode pair can be with last selection course in identical electrode pair 5,6, or different electrode pair.The latter may be following situation: because electrothermal therapy, the impedance of tissue increases between the electrode 5 and 6, makes it be higher than the impedance of the tissue between another counter electrode at least.
The subarray 19 of electrod-array 7 can also comprise the electrode more than two.In this case, pre-determine an impedance threshold and suit, this threshold value whether preestablish to counter electrode between tissue apply high frequency electric.If the impedance between the electrode pair does not does not meet or exceed this impedance threshold, then incorporate the electrode pair of being paid close attention to into subarray 19.
In an alternative arrangements of the present invention, in applying the process of high frequency electric, measuring device 13 continuous measurement impedance between electrodes, and as long as the amplification of impedance of organizing between the electrode 5 and 6 or impedance surpasses predetermined threshold, just to control unit 11 output signals.Control unit stops applying high frequency electric subsequently.After stopping applying high frequency electric, control unit 11 makes measuring device 13 measure the impedance of organizing between all electrode pairs once more, and subsequently according to the result of impedance measurement process, make selector installation 15 select the new subarray 19 of electrod-arrays 7, apply high frequency electric by this new subarray 19 to tissue then.
If subarray 19 comprises the electrode more than two, can suppose that then control device 11 just stops applying high frequency electric as long as the impedance between a pair of in a plurality of electrode pairs surpasses predetermined value or alternatively surpasses predetermined impedance threshold when the impedance of the tissue between the electrode pair of predetermined quantity.
An alternative embodiment of the present invention is represented as circuit block diagram in Fig. 2.By identical label represent with embodiment shown in Figure 1 in identical assembly, and no longer be described hereinafter.
This alternative configuration and different being embodiment illustrated in fig. 1 have the switch element 12 with control unit 11 isolating unit forms.With switch element 12 directly links to each other high frequency maker 17 and A/D converter 14 arranged, the analog signal conversion that A/D converter 14 is used for being obtained by impedance measurement is a digital signal, and this digital signal is transmitted to processor 16.Switch element 12 is used for each electrode 1-6 is connected respectively to high frequency maker 17 and/or A/D converter 14.
Alternatively, control unit 11 can be connected to high frequency maker 17 in addition by control circuit, can regulate the frequency of the high frequency voltage that is transmitted by high frequency maker 17.
In an illustrated embodiment, active electrode is the form of electrode needle.The kind electrode pin has been shown in Fig. 3 a.Its near-end (that is, protruding into that outside end of tissue), electrode needle 100 has handle district 102, and its end (that is, be inserted into that end 104 in the tissue), has two active electrodes 120 and 122 (seeing Fig. 3 b).Being arranged between two electrodes 120 and 122 is insulation layer 124, and this insulation layer 124 makes two electrode electrically insulated from one another.Though the electrode needle shown in Fig. 3 a and Fig. 3 b has two electrodes, electrode needle also can have more than two active electrode or have only an electrode.If there is active electrode, then between all electrodes, has separately an insulation layer more than two.All electrodes of electrode needle 100 link to each other with the control device (not shown) by separate lines separately, so that can apply high frequency voltage respectively to each electrode.
Portion within it, electrode needle 100 can comprise that one or more is used to provide fluid with cooling or heat the passage of this active electrode or whole pin.
Fig. 4 a and 4b illustrate first example of the application of this bringing device.The figure shows pathological tissue 200 (destination organization), three electrode needle 100 inserted in the pathological tissues 200 by puncture so that the active electrode 120 of three electrode needle and 122 and this destination organization directly electrically contact.
At first apply high frequency voltage to electrode 120 and 122, so that high frequency electric axially between electrode 120 and 122, flowing along electrode needle 100 by control unit 11.These electric currents have been shown in Fig. 4 b, and corresponding electromotive force has been shown in Fig. 4 a by a dotted line.
Fig. 4 a represents the plane graph of three electrode needle 100, and Fig. 4 b represents two side view in three electrode needle 100.The stack of the electric current by all three electrode needle 100 has produced electric current uniform tissue zone, thereby can realize the even heating of this tissue regions between these pins.
Simultaneously, along with applying of high frequency electric, utilize measuring device 13 in the tissue impedance between the measurement electrode 120 and 122 under operating frequency or other frequency.Particularly,, then apply, can measure the impedance of the tissue between the single electrode pair, and the electric current that applies can not hinder this measuring process substantially by ongoing if adopted the frequency not corresponding for this reason with operating frequency.For this reason, this measuring device comprises descriminator or wave filter, and this descriminator or wave filter can separate impedance measurement frequency (for example 20kHz) with operating frequency (for example 470kHz).
Fig. 5 a and Fig. 5 b represent another example according to the application of bringing device of the present invention.In this embodiment, not that three electrode needle 100 are inserted in the destination organization, but be inserted in the outside of destination organization, destination organization is arranged between three electrode needle 100 by puncture.Opposite with the example shown in Fig. 4 a and Fig. 4 b, in this case, the axis of electric current and pin is not parallel, but from an electrode needle to another electrode needle.In this way, can in destination organization 200, obtain uniform electric current.In addition, can avoid when removing electrode needle, carrying secretly malignant tissue.
This bringing device can only use along the mobile axial current of pin or only use between two different pins mobile electric current or use both combinations to carry out work.After reselecting the subarray of active electrode, the mobile direction of electric current can switch to another kind of pattern from a kind of pattern.
Though the mode by example has illustrated the electrod-array with 6 electrodes in each embodiment, electrod-array also can comprise the electrode greater or less than 6.
Claims (20)
1. a bringing device is used to apply high frequency electric, and to carry out the thermmohardening of soma, this bringing device comprises: the electrod-array that is connected (7) has at least three active electrodes (1-6) that can insert in the soma; High frequency maker (17) is used to produce high frequency voltage, and one or more in this high frequency maker and the described electrode (1-6) switchably is connected; And measuring device (13), be used to measure the impedance of the soma between all or the selected active electrode (1-6), this bringing device is characterised in that: selector installation (15), link to each other with described measuring device (13), and be used for comprising from described electrod-array (7) selection the subarray (19) of at least two active electrodes (5,6) according to measured impedance; And control device (11), link to each other with described selector installation (15), and the active electrode (5,6) that is used for to selected subarray (19) applies high frequency voltage, so that high frequency electric flows between the active electrode (5,6) of selected subarray (19) by soma; Wherein, described selector installation (15) is designed so that: if impedance, ohmage between the active electrode of the predetermined quantity of described subarray (5,6), the variation of impedance or the variation of ohmage meet or exceed a predetermined value, and then described selector installation (15) is selected the new subarray (19) that comprises at least two effect resistance (5,6) automatically.
2. bringing device according to claim 1 is characterized in that, described measuring device be used for according to measured impedance obtain the ohmage between the active electrode of the predetermined quantity of the subarray of connection electrode (19) (5,6) to some extent.
3. bringing device according to claim 1 and 2, it is characterized in that, described selector installation (15) has following structure: when when last time selecting to begin through the scheduled time, this selector installation (15) automatically performs new impedance measurement operation, and reselects the subarray (19) that comprises at least two active electrodes (5,6).
4. bringing device according to claim 1 is characterized in that, described measuring device (13) is used for measuring in the process that applies high frequency electric the impedance or the ohmage of the soma between the active electrode (1-6).
5. bringing device according to claim 1, it is characterized in that, described selector installation (15) has following structure: select or reselect comprise at least two active electrodes (5,6) subarray (19) before, described selector installation (15) makes measuring device (13) measure the impedance or the ohmage of the soma between all possible pairing of active electrode (1-6), and those active electrodes (1-6) variation of the variation of the impedance between it, ohmage, impedance or ohmage is minimum or that do not surpass a predetermined value are chosen as subarray (19).
6. bringing device according to claim 1, it is characterized in that, described control device (11) has following structure: applying the beginning of process, to impose on described active electrode (1-6) with the high frequency voltage that predetermined period changes, and the subarray (19) that basis selects to comprise at least two active electrodes (5,6) in time at the impedance or the ohmage of moment generation after a while in applying process.
7. bringing device according to claim 1 is characterized in that, described selector installation (15) or described control device (11) are designed to: disconnect impedance or ohmage and surpass a predetermined maximum R
MaxSubarray or combination of electrodes, and in further handling, no longer considering described subarray or combination of electrodes.
8. bringing device according to claim 7 is characterized in that, described control device (11) is used for peak power P to be carried
MaxReduce to scheduled volume, this peak power P
MaxBe to surpass less than R
MaxQualification impedance or predetermined by the subarray of selecting respectively (19) when limiting ohmage.
9. bringing device according to claim 1 is characterized in that, described selector installation (15) or control device (11) are designed to: disconnect impedance or ohmage less than predetermined minimum value R
MinSubarray or combination of electrodes.
10. bringing device according to claim 1, it is characterized in that, described control device (11) at chooser array (19) afterwards, the power initial adjustment that to carry by the subarray of selecting respectively (19) is for lower, and within the predetermined time, with one or more stage or continuously this power is increased to predetermined peak power P
Max
11. bringing device according to claim 1, it is characterized in that, described selector installation (15) is designed to: select at least three active electrodes as subarray (19), and described control device (11) is designed to: make active electrode be subjected to distinguishing phase shift each other the effect of the high frequency voltage of constant phase angle.
12. bringing device according to claim 11 is characterized in that, selected subarray (19) comprises three active electrodes, and described phase angle is 120 degree.
13. bringing device according to claim 1 is characterized in that, described active electrode (1-6) is arranged on a plurality of electrode needle (100).
14. bringing device according to claim 13 is characterized in that, described electrode needle (100) is the bipolar electrode pin.
15. bringing device according to claim 13 is characterized in that, described electrode needle (100) is the multi-electrode type electrode needle.
16. bringing device according to claim 13 is characterized in that, described electrode needle (100) is surrounded by insulation sleeve, and can extend predetermined length from described insulation sleeve.
17. any described bringing device according in the claim 13 to 16 is characterized in that, described electrode needle (100) has the fluid passage that is used for the cooling or heats described electrode needle (100).
18. bringing device according to claim 17 is characterized in that, described passage leads to described active electrode (1-6), and is used to provide cooling fluid.
19. bringing device according to claim 17 is characterized in that, described fluid is a deionization liquid.
20. bringing device according to claim 1, it is characterized in that, described high frequency maker, described measuring device, described selector installation and described control device are combined in one or more housing together, apply maker with formation, this applies maker and has the connecting pin that is used for described electrode and feeder line thereof.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10224154.6 | 2002-05-27 | ||
| DE2002124154 DE10224154A1 (en) | 2002-05-27 | 2002-05-27 | Application device for electrosurgical device for body tissue removal via of HF current has electrode subset selected from active electrode set in dependence on measured impedance of body tissue |
| DE10317243.2 | 2003-04-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1787788A CN1787788A (en) | 2006-06-14 |
| CN100409822C true CN100409822C (en) | 2008-08-13 |
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ID=29557423
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB038120747A Expired - Lifetime CN100409822C (en) | 2002-05-27 | 2003-05-23 | Device for electrosurgically destroying body tissue |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN100409822C (en) |
| DE (1) | DE10224154A1 (en) |
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| US5383917A (en) * | 1991-07-05 | 1995-01-24 | Jawahar M. Desai | Device and method for multi-phase radio-frequency ablation |
| WO2002032335A1 (en) * | 2000-07-25 | 2002-04-25 | Rita Medical Systems Inc. | Apparatus for detecting and treating tumors using localized impedance measurement |
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| Publication number | Publication date |
|---|---|
| DE10224154A1 (en) | 2003-12-18 |
| CN1787788A (en) | 2006-06-14 |
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