CA2735739A1 - Healthcare facility disinfecting process and system with oxygen/ozone mixture - Google Patents
Healthcare facility disinfecting process and system with oxygen/ozone mixture Download PDFInfo
- Publication number
- CA2735739A1 CA2735739A1 CA2735739A CA2735739A CA2735739A1 CA 2735739 A1 CA2735739 A1 CA 2735739A1 CA 2735739 A CA2735739 A CA 2735739A CA 2735739 A CA2735739 A CA 2735739A CA 2735739 A1 CA2735739 A1 CA 2735739A1
- Authority
- CA
- Canada
- Prior art keywords
- ozone
- room
- oxygen
- atmosphere
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/20—Gaseous substances, e.g. vapours
- A61L2/202—Ozone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/20—Gaseous substances, e.g. vapours
- A61L2/208—Hydrogen peroxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/10—Apparatus features
- A61L2202/11—Apparatus for generating biocidal substances, e.g. vaporisers, UV lamps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/10—Apparatus features
- A61L2202/13—Biocide decomposition means, e.g. catalysts, sorbents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/10—Apparatus features
- A61L2202/14—Means for controlling sterilisation processes, data processing, presentation and storage means, e.g. sensors, controllers, programs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/20—Targets to be treated
- A61L2202/25—Rooms in buildings, passenger compartments
Abstract
A system and process for disinfecting rooms such as health care facility rooms with oxygen/ozone mix-ture is described, which is effective to combat "superbugs" such as Clostridi-um difficile (C. difficile); E. coli; Pseu-domonas aeruginosa; methicillin-resis-tant Staphylococcus aureus (MRSA); and vancomycin-resistant Enterococcus (VRE). In preferred embodiments, hy-drogen peroxide is additionally used. The system and process is effective to destroy bacteria deposited on surfaces as biofilm, and, accompanied by physi-cal agitation such as jet nozzle outlets, is effective to disinfect carpet, drapery and similar absorbent and porous sur-faces.
Claims (38)
1. A process of combating bacteria in an enclosed space within a room and contained in biofilm on surfaces within the room, which comprises:
creating in the room a disinfecting atmosphere which includes ozone at a concentration of 2 - 350 ppm by weight and hydrogen peroxide at an amount of 0.2 - 10 wt. %, at a relative humidity of at least 60%;
exposing the biofilm carrying surfaces having live bacteria therein to the disinfecting atmosphere for a period of at least 30 minutes sufficient for an effective kill of the bacteria in the microfilm;
and subsequently removing ozone from the atmosphere, down to 0,04 ppm or less.
creating in the room a disinfecting atmosphere which includes ozone at a concentration of 2 - 350 ppm by weight and hydrogen peroxide at an amount of 0.2 - 10 wt. %, at a relative humidity of at least 60%;
exposing the biofilm carrying surfaces having live bacteria therein to the disinfecting atmosphere for a period of at least 30 minutes sufficient for an effective kill of the bacteria in the microfilm;
and subsequently removing ozone from the atmosphere, down to 0,04 ppm or less.
2. The process of claim 11 wherein the time of exposure is from about 30 minutes to about 120 minutes.
3. The process of claim 1 or claim 2 wherein the ozone concentration in the disinfecting atmosphere is from 20 to 200 ppm.
4. The process of claim 3 wherein the ozone concentration in the disinfecting atmosphere is from 35 - 100 ppm.
5. The process of any preceding claim wherein the hydrogen peroxide amount is from 0.5 - 10 %.
6. The process of claim 5 wherein the hydrogen peroxide amount in the disinfecting atmosphere is from 1 - 5 %.
7. The process of any preceding claim wherein the bacteria being combated are Clostridium difficile (C. difficile); E. coli; Pseudomonas aeruginosa; methicillin-resistant Staphylococcus aureus (MRSA);
vancomycin-resistant Enterococcus (VRE); or combinations of two or more of said bacteria.
vancomycin-resistant Enterococcus (VRE); or combinations of two or more of said bacteria.
8. The process of any of claims 1 -6 wherein the bacteria being treated is Bacillus subtilis or anthrax, or a combination thereof.
9. The process of any preceding claim including the additional step of subjecting porous and fibrous surfaces within the room to physical agitation while exposed to the disinfecting atmosphere.
10. The process of claim 9 wherein the physical agitation is conducted with application of bristles.
11. The process of claim 9 wherein the physical agitation is conducted with application of air pressure jets.
12. The process of claim 9 wherein the physical agitation is conducted with application of ultrasonic energy, radio-frequency energy or electromagnetic waves, capable of causing physical disruption.
13. The process of any preceding claim wherein the biofilm carrying surfaces are exposed to a localized stream of the disinfecting atmosphere.
14. The process of any preceding claim wherein the pressure of the disinfecting atmosphere when the biofilm carrying surfaces are exposed thereto is above atmospheric pressure.
15. The process of claim 14 wherein the pressure of the disinfecting atmosphere is from 14.7 to 100 psi.
16. A process for disinfecting a room and surfaces therein, which comprises:
introducing into the room an oxygen/ozone gas mixture;
raising the pressure within the room above atmospheric pressure;
physically agitating fibrous and porous surfaces within the room while the surfaces are exposed to the ozone containing atmosphere at a relative humidity of at least 70%;
returning the room to atmospheric pressure, and removing the residual ozone from the room's atmosphere, down to a maximum level of 0.04 ppm.
introducing into the room an oxygen/ozone gas mixture;
raising the pressure within the room above atmospheric pressure;
physically agitating fibrous and porous surfaces within the room while the surfaces are exposed to the ozone containing atmosphere at a relative humidity of at least 70%;
returning the room to atmospheric pressure, and removing the residual ozone from the room's atmosphere, down to a maximum level of 0.04 ppm.
17. The process of claim 16 wherein the ozone is delivered to the room atmosphere as a mixed oxygen/ozone gas, with the ozone present in an approximate amount of 10 - 100 ppm.
18. The process of claim 17 wherein the ozone is delivered to the room atmosphere as a mixed oxygen/ozone gas, with the ozone present in an approximate amount of 30 - 90 ppm.
19. The process of claim 18 wherein the ozone is delivered to the room atmosphere as a mixed oxygen/ozone gas, with the ozone present in an approximate amount of 35 - 80 ppm.
20. The process of any of claims 16 - 19 wherein the pressure within the room is raised to between 14.7 psi and 100 psi.
21. The process of any of claims 16 - 20 wherein the room and its surfaces are exposed to the oxygen/ozone mixture for a period of from about 45 to 120 minutes.
22. The process of claim 21 wherein the room and its surfaces are exposed to the oxygen/ozone mixture for a period of from about 60 to 105 minutes.
23. The process of any of claims 16 - 22 applied to disinfection of at least one of the bacteria Clostridium difficile (C. difficile); E. coli; Pseudomonas aeruginosa; methicillin-resistant Staphylococcus aureus (MRSA); and vancomycin-resistant Enterococcus (VRE).
24. The process of any of claims 16 - 23 which additionally includes introduction into the room of an effective amount of hydrogen peroxide.
25 A portable system for disinfecting rooms and surfaces therein with ozone, comprising:
an ozone generator discharging a mixture of oxygen and ozone;
an ozone controller adapted to control the proportion of ozone in the mixture of oxygen and ozone;
a discharge tube to receive the mixture of oxygen and ozone from the ozone generator, the discharge tube having an outlet end;
a physical agitation system at the outlet end of the discharge tube, for physically agitating surfaces with oxygen/ozone mixture issuing therefrom;
pressure adjusting means connected to the ozone generator arranged to adjust the pressure of the oxygen/ozone mixture discharged by the physical agitation system and the oxygen/ozone gas pressure in the room under treatment;
temperature adjusting means connected to the ozone generator arranged to adjust the temperature of the oxygen/ozone mixture discharged by the scrubbing system;
humidity adjusting means adapted to humidify the treatment location to a relative humidity of at least 65%;
and an ozone remover adapted to receive oxygen/ozone mixture from the environment of use of the discharge tube and to remove ozone from the mixture.
an ozone generator discharging a mixture of oxygen and ozone;
an ozone controller adapted to control the proportion of ozone in the mixture of oxygen and ozone;
a discharge tube to receive the mixture of oxygen and ozone from the ozone generator, the discharge tube having an outlet end;
a physical agitation system at the outlet end of the discharge tube, for physically agitating surfaces with oxygen/ozone mixture issuing therefrom;
pressure adjusting means connected to the ozone generator arranged to adjust the pressure of the oxygen/ozone mixture discharged by the physical agitation system and the oxygen/ozone gas pressure in the room under treatment;
temperature adjusting means connected to the ozone generator arranged to adjust the temperature of the oxygen/ozone mixture discharged by the scrubbing system;
humidity adjusting means adapted to humidify the treatment location to a relative humidity of at least 65%;
and an ozone remover adapted to receive oxygen/ozone mixture from the environment of use of the discharge tube and to remove ozone from the mixture.
26. The system of claim 25 wherein the humidity adjusting means is a humidifier interposed between the ozone generator and the oxygen container, with input from the oxygen container and output to the ozone generator.
27. The system of claim 25 or claim 26 wherein the ozone generator is fed with medical grade oxygen and the ozone controller is electrical discharge plates disposed within the ozone generator, adapted to supply variable, controlled voltage to the oxygen gas supplied thereto.
28. The system of any of claims 25 - 27 wherein the physical agitation system comprises at least one jet nozzle outlet.
29. The system of claim 28 wherein the physical agitation system further includes bristles disposed adjacent to the jet nozzle outlet and protruding slightly below the discharge end thereof.
30. The system of any of claims 25 - 29 wherein the ozone generator includes at least one oxygen/ozone outlet to the room in addition to the discharge tube.
31. The system of any of claims 25 - 30 further including a wheeled cart for loading and transportation of the system.
32. A portable system for disinfecting rooms, surfaces and equipment therein, comprising:
an ozone generator for discharging into the room a gaseous mixture including ozone;
an ozone controller adapted to control the amount of discharged ozone ;
a source of hydrogen peroxide for discharging controlled amounts of hydrogen peroxide into the room;
means for discharging the hydrogen peroxide and ozone into the room;
humidity adjusting means adapted to increase or decrease the relative humidity of the room during treatment;
and an ozone remover adapted to destroy ozone, down to a safe level in the room atmosphere for subsequent human utilization.
an ozone generator for discharging into the room a gaseous mixture including ozone;
an ozone controller adapted to control the amount of discharged ozone ;
a source of hydrogen peroxide for discharging controlled amounts of hydrogen peroxide into the room;
means for discharging the hydrogen peroxide and ozone into the room;
humidity adjusting means adapted to increase or decrease the relative humidity of the room during treatment;
and an ozone remover adapted to destroy ozone, down to a safe level in the room atmosphere for subsequent human utilization.
33. The system of claim 32 wherein the means for discharging the hydrogen peroxide and ozone into the room includes a discharge wand having an outlet end.
34. The system of claim 33 wherein the outlet end of the discharge wand includes a dislodgement system for agitating and disturbing surfaces to which it is applied.
35. The system of claim 34 wherein the dislodgement system is a jet nozzle outlet.
36. The system of claim 34 or claim 35 wherein the dislodgement system includes bristles for scrubbing action.
37. The system of any of claims 32 - 36 wherein the means for discharging hydrogen peroxide gas and ozone further includes an outlet which bypasses the wand.
38. The system of any of claims 32 - 37 further including a wheeled cart for loading and transportation of the system.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22321909P | 2009-07-06 | 2009-07-06 | |
US61/223,219 | 2009-07-06 | ||
US29585110P | 2010-01-18 | 2010-01-18 | |
US61/295,851 | 2010-01-18 | ||
PCT/CA2010/000998 WO2011003179A1 (en) | 2009-07-06 | 2010-07-05 | Healthcare facility disinfecting process and system with oxygen/ozone mixture |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2735739A1 true CA2735739A1 (en) | 2011-01-13 |
CA2735739C CA2735739C (en) | 2011-11-22 |
Family
ID=43428698
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2735739A Active CA2735739C (en) | 2009-07-06 | 2010-07-05 | Healthcare facility disinfecting process and system with oxygen/ozone mixture |
Country Status (11)
Country | Link |
---|---|
US (1) | US8551399B2 (en) |
EP (1) | EP2451489B1 (en) |
JP (1) | JP2012531979A (en) |
KR (1) | KR20120035206A (en) |
CN (1) | CN102481383B (en) |
BR (1) | BR112012000384B1 (en) |
CA (1) | CA2735739C (en) |
IN (1) | IN2012DN00963A (en) |
MX (1) | MX344243B (en) |
SG (1) | SG176977A1 (en) |
WO (1) | WO2011003179A1 (en) |
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WO2015048903A1 (en) * | 2013-10-04 | 2015-04-09 | Medizone International Inc. | Healthcare facility disinfecting system |
CN105880198A (en) * | 2016-03-22 | 2016-08-24 | 王慧丽 | Cleaning and disinfecting device for pediatric nursing |
USRE47582E1 (en) | 2009-07-28 | 2019-08-27 | Sterifre Medical, Inc. | Free radical sterilization system and method |
US11253620B2 (en) | 2016-06-17 | 2022-02-22 | Sterifre Medical, Inc. | Sterilization, disinfection, sanitization, decontamination, and therapeutic devices, systems, and methods |
US11344643B2 (en) | 2017-10-25 | 2022-05-31 | Sterifre Medical, Inc. | Devices, systems, and methods for sterilization, disinfection, sanitization and decontamination |
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-
2010
- 2010-07-05 BR BR112012000384A patent/BR112012000384B1/en active IP Right Grant
- 2010-07-05 JP JP2012518702A patent/JP2012531979A/en active Pending
- 2010-07-05 CA CA2735739A patent/CA2735739C/en active Active
- 2010-07-05 WO PCT/CA2010/000998 patent/WO2011003179A1/en active Application Filing
- 2010-07-05 KR KR1020127003131A patent/KR20120035206A/en not_active Application Discontinuation
- 2010-07-05 SG SG2011095767A patent/SG176977A1/en unknown
- 2010-07-05 CN CN201080030657.2A patent/CN102481383B/en active Active
- 2010-07-05 EP EP10796611.1A patent/EP2451489B1/en active Active
- 2010-07-05 MX MX2012000302A patent/MX344243B/en active IP Right Grant
- 2010-07-05 IN IN963DEN2012 patent/IN2012DN00963A/en unknown
-
2012
- 2012-01-04 US US13/343,403 patent/US8551399B2/en active Active
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USRE47582E1 (en) | 2009-07-28 | 2019-08-27 | Sterifre Medical, Inc. | Free radical sterilization system and method |
USRE49474E1 (en) | 2009-07-28 | 2023-03-28 | Sterifre Medical, Inc. | Free radical sterilization system and method |
WO2015048903A1 (en) * | 2013-10-04 | 2015-04-09 | Medizone International Inc. | Healthcare facility disinfecting system |
CN105880198A (en) * | 2016-03-22 | 2016-08-24 | 王慧丽 | Cleaning and disinfecting device for pediatric nursing |
US11253620B2 (en) | 2016-06-17 | 2022-02-22 | Sterifre Medical, Inc. | Sterilization, disinfection, sanitization, decontamination, and therapeutic devices, systems, and methods |
US11344643B2 (en) | 2017-10-25 | 2022-05-31 | Sterifre Medical, Inc. | Devices, systems, and methods for sterilization, disinfection, sanitization and decontamination |
Also Published As
Publication number | Publication date |
---|---|
MX2012000302A (en) | 2012-06-19 |
US20120100037A1 (en) | 2012-04-26 |
JP2012531979A (en) | 2012-12-13 |
CN102481383A (en) | 2012-05-30 |
WO2011003179A1 (en) | 2011-01-13 |
BR112012000384B1 (en) | 2018-07-17 |
CA2735739C (en) | 2011-11-22 |
BR112012000384A2 (en) | 2017-06-13 |
KR20120035206A (en) | 2012-04-13 |
US8551399B2 (en) | 2013-10-08 |
IN2012DN00963A (en) | 2015-04-10 |
EP2451489B1 (en) | 2016-06-29 |
CN102481383B (en) | 2015-11-25 |
EP2451489A1 (en) | 2012-05-16 |
EP2451489A4 (en) | 2014-07-30 |
SG176977A1 (en) | 2012-02-28 |
MX344243B (en) | 2016-12-08 |
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