CA2711262A1 - Dental composition comprising a basic amino acid for alleviating tooth sensitivity - Google Patents

Dental composition comprising a basic amino acid for alleviating tooth sensitivity Download PDF

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Publication number
CA2711262A1
CA2711262A1 CA 2711262 CA2711262A CA2711262A1 CA 2711262 A1 CA2711262 A1 CA 2711262A1 CA 2711262 CA2711262 CA 2711262 CA 2711262 A CA2711262 A CA 2711262A CA 2711262 A1 CA2711262 A1 CA 2711262A1
Authority
CA
Canada
Prior art keywords
composition
fluoride
recited
dental
sealant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2711262
Other languages
French (fr)
Other versions
CA2711262C (en
Inventor
Michael Prencipe
Rajnish Kohli
Richard Scott Robinson
Richard J. Sullivan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Colgate Palmolive Co
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2711262A1 publication Critical patent/CA2711262A1/en
Application granted granted Critical
Publication of CA2711262C publication Critical patent/CA2711262C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0216Solid or semisolid forms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00Preparations for dentistry
    • A61K6/20Protective coatings for natural or artificial teeth, e.g. sealings, dye coatings or varnish
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20Halogens; Compounds thereof
    • A61K8/21Fluorides; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A61Q11/02Preparations for deodorising, bleaching or disinfecting dentures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/22Gas releasing
    • A61K2800/222Effervescent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41Particular ingredients further characterized by their size
    • A61K2800/412Microsized, i.e. having sizes between 0.1 and 100 microns

Abstract

The invention provides a method of treating sensitive teeth comprising attaching a sealant composition comprising a basic amino acid to a person's tooth and allowing the basic amino acid to be slowly released over time in order to reduce chrome and/or acute tooth sensitivity together with compositions and methods of use.

Claims (24)

1. A method of treating sensitive teeth comprising: attaching a sealent composition comprising a basic amino acid in free or salt form (BAA) to a tooth of a person in need thereof; and allowing BAA to be slowly released over time in order to reduce chronic and/or acute tooth sensitivity.
2. The method as recited in claim 1, wherein the composition additionally comprises fluoride.
3. The method as recited in claim 2, wherein fluoride is slowly released over time.
4. The method as recited in claim 3, wherein the fluoride ions are included in compounds selected from the group consisting of aluminum fluoride, sodium hydrogen fluoride, sodium fluoride, calcium fluoride, magnesium fluoride, and potassium fluoride.
5. The method as recited in claim 2, wherein at least about 12 weight percent of fluoride is included in the composition.
6. The method as recited in claim 2, wherein about 15 to about 25 weight percent fluoride is included in the composition.
7. The method as recited in claim 2, wherein the composition has a DDR in the range of about 0.1 to about 100 %.
8. The method as recited in claim 2, wherein the composition has a DDR in the range of about 0.1 to about 0.5 %.
9. The method as recited in claim 2, wherein the composition is provided in powder form.
10. The method as recited in claim 9, wherein the powder form of the sealant composition comprises powder grains having a grain size of less than about 38 microns.
11. The method as recited in claim 10, wherein the powder form of the sealant composition comprises powder grains having a grain size of less than about 106 microns.
12. The method as recited in claim 10, wherein the powdered composition is incorporated in one or more dental materials.
13. The method as recited in claim 12, wherein the dental material is selected from the group consisting of a dental amalgam, a fissure sealant resin, a composite bonding material, an orthodontic appliance, a dental prosthetic, a resin varnish, and an oral surgery implant.
14. The method as recited in claim 2, wherein the composition comprises at least one pellet that may be attached to a tooth using dental cement, wherein said at least one pellet comprises BAA.
15. A dental sealant composition comprising a basic amino acid in free or salt form (BAA).
16. The sealant composition of claim 15 which additionally comprises fluoride.
17. The sealant composition of claim 15 or 16 wherein the BAA comprises arginine, in free or salt form.
18. The sealant composition of any of claims 15 17 comprising aluminum fluoride, sodium hydrogen fluoride, sodium fluoride, calcium fluoride, magnesium fluoride, or potassium fluoride.
19. The sealant composition of any of claims 15 18 wherein at least about 12 weight percent of fluoride is included in the composition.
20. The sealant composition of any of claims 15 19, wherein the composition has a DDR in the range of about 0. 1 to about 100 %.
21. The sealant composition of claim 20, wherein the composition has a DDR in the range of about 0.1 to about 0.5 %.
22. The sealant composition of any of claims 15 - 21, wherein the composition is provided in powder form.
23. The sealant composition of any of claims 15 - 22, incorporated into a dental material selected from the group consisting of a dental amalgam, a fissure sealant resin, a composite bonding material, an orthodontic appliance, a dental prosthetic, a rosin varnish, and an oral surgery implant.
24. The use of a basic amino acid in free or salt form in the manufacture of a dental sealant composition.
CA2711262A 2008-02-08 2009-02-06 Dental composition comprising a basic amino acid for alleviating tooth sensitivity Expired - Fee Related CA2711262C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2742508P 2008-02-08 2008-02-08
US61/027,425 2008-02-08
PCT/US2009/033312 WO2009100283A2 (en) 2008-02-08 2009-02-06 Tooth sealant

Publications (2)

Publication Number Publication Date
CA2711262A1 true CA2711262A1 (en) 2009-08-13
CA2711262C CA2711262C (en) 2015-06-23

Family

ID=40952706

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2711262A Expired - Fee Related CA2711262C (en) 2008-02-08 2009-02-06 Dental composition comprising a basic amino acid for alleviating tooth sensitivity

Country Status (14)

Country Link
US (1) US10391038B2 (en)
EP (1) EP2249764B1 (en)
JP (2) JP2011510095A (en)
CN (1) CN101938970A (en)
AR (1) AR070589A1 (en)
AU (1) AU2009212339B2 (en)
BR (1) BRPI0907103A2 (en)
CA (1) CA2711262C (en)
CO (1) CO6241091A2 (en)
MX (1) MX2010007738A (en)
RU (1) RU2493812C2 (en)
TW (1) TWI376237B (en)
WO (1) WO2009100283A2 (en)
ZA (1) ZA201003694B (en)

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US9078840B2 (en) 2013-02-15 2015-07-14 Dentsply International Inc. Dental varnish compositions
MX2017007856A (en) * 2014-12-24 2017-09-19 Colgate Palmolive Co Oral care composition.
US10512668B2 (en) 2014-12-29 2019-12-24 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for delivering lypophilic agents to dental pulp and for enhancing dentin production
CN104758311A (en) * 2015-04-24 2015-07-08 杭州维瓦科技有限公司 Compound for treating hemodia and preparation method thereof
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CN106361579A (en) * 2016-11-10 2017-02-01 李雨阳 Production method of tooth surface self-cleaning anti-adhesion coating

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Also Published As

Publication number Publication date
WO2009100283A2 (en) 2009-08-13
JP2014088419A (en) 2014-05-15
EP2249764A4 (en) 2012-02-22
AU2009212339B2 (en) 2011-12-22
AU2009212339A1 (en) 2009-08-13
EP2249764A2 (en) 2010-11-17
CA2711262C (en) 2015-06-23
BRPI0907103A2 (en) 2016-05-03
RU2493812C2 (en) 2013-09-27
EP2249764B1 (en) 2019-07-31
TWI376237B (en) 2012-11-11
WO2009100283A3 (en) 2009-11-12
TW201000143A (en) 2010-01-01
US20100316726A1 (en) 2010-12-16
JP2011510095A (en) 2011-03-31
CN101938970A (en) 2011-01-05
CO6241091A2 (en) 2011-01-20
RU2010137322A (en) 2012-03-20
MX2010007738A (en) 2010-08-10
US10391038B2 (en) 2019-08-27
AR070589A1 (en) 2010-04-21
ZA201003694B (en) 2014-11-26

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