CA2667952A1 - Infusion devices and methods - Google Patents
Infusion devices and methods Download PDFInfo
- Publication number
- CA2667952A1 CA2667952A1 CA002667952A CA2667952A CA2667952A1 CA 2667952 A1 CA2667952 A1 CA 2667952A1 CA 002667952 A CA002667952 A CA 002667952A CA 2667952 A CA2667952 A CA 2667952A CA 2667952 A1 CA2667952 A1 CA 2667952A1
- Authority
- CA
- Canada
- Prior art keywords
- medical device
- user
- infusion
- analyte
- access
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
- A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F21/00—Security arrangements for protecting computers, components thereof, programs or data against unauthorised activity
- G06F21/30—Authentication, i.e. establishing the identity or authorisation of security principals
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F21/00—Security arrangements for protecting computers, components thereof, programs or data against unauthorised activity
- G06F21/30—Authentication, i.e. establishing the identity or authorisation of security principals
- G06F21/44—Program or device authentication
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
- G16H20/17—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
- G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
- G16H40/63—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
- G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
- G16H40/67—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16Z—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS, NOT OTHERWISE PROVIDED FOR
- G16Z99/00—Subject matter not provided for in other main groups of this subclass
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04L—TRANSMISSION OF DIGITAL INFORMATION, e.g. TELEGRAPHIC COMMUNICATION
- H04L63/00—Network architectures or network communication protocols for network security
- H04L63/10—Network architectures or network communication protocols for network security for controlling access to devices or network resources
- H04L63/104—Grouping of entities
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04L—TRANSMISSION OF DIGITAL INFORMATION, e.g. TELEGRAPHIC COMMUNICATION
- H04L63/00—Network architectures or network communication protocols for network security
- H04L63/10—Network architectures or network communication protocols for network security for controlling access to devices or network resources
- H04L63/105—Multiple levels of security
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04W—WIRELESS COMMUNICATION NETWORKS
- H04W12/00—Security arrangements; Authentication; Protecting privacy or anonymity
- H04W12/08—Access security
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/27—General characteristics of the apparatus preventing use
- A61M2205/276—General characteristics of the apparatus preventing use preventing unwanted use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/35—Communication
- A61M2205/3546—Range
- A61M2205/3561—Range local, e.g. within room or hospital
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/35—Communication
- A61M2205/3546—Range
- A61M2205/3569—Range sublocal, e.g. between console and disposable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31525—Dosing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31546—Electrically operated dose setting, e.g. input via touch screen or plus/minus buttons
Abstract
Medical devices having restrictive access, and methods thereof are provided.
Description
INFUSION DEVICES AND METHODS
PRIORITY
This application claims priority to US patent application serial no.
11/555,207 filed October 31, 2006, entitled "Infusion Devices And Methods," and is incorporated herein by reference for all purposes.
BACKGROUND OF THE INVENTION
A variety of medical devices are employed to monitor a health condition. For example, devices include those designed to enable a user to manage a health condition based at least in part on the level of analyte in the body. These types of devices include analyte determination devices, drug delivery devices, and the like.
Such analyte devices have become widely used in recent years for people with diabetes. Diabetics have typically measured their blood glucose level by lancing a finger tip or other body location (i.e., alternate site) to draw blood, applying the blood to a disposable test strip in a hand-held meter and allowing the meter and strip to perform an electrochemical test of the blood to determine the current glucose concentration. Such discrete or individual, in vitro tests are typically conducted at least several times per day. Detailed descriptions of such glucose monitoring systems and their use are provided in U.S. Patent No. 7,058,437, issued to TheraSense, Inc., on June 6, 2006, which is incorporated by reference herein in its entirety.
In vivo glucose monitoring devices are designed to provide continuous glucose monitoring. Some of these continuous systems employ a disposable, transcutaneous sensor that is inserted into the skin to measure glucose concentrations in interstitial fluid. A portion of the sensor protrudes from the skin and is coupled with a durable controller and transmitter unit that is attached to the skin with adhesive. A
wireless handheld unit is used in combination with the skin-mounted transmitter and sensor to receive glucose readings periodically, such as once a minute. At a predetermined time interval, such as every three, five or seven days, the disposable sensor is removed and replaced with a fresh sensor which is again coupled to the reusable controller and transmitter unit. With this arrangement, a person with diabetes may continuously monitor their glucose level with the handheld unit. The handheld unit of the in vivo system can also include an in vitro test strip meter for conducting individual tests as described above. The in vitro test strip meter can be used to calibrate the continuous monitoring system each time a new in vivo sensor is implanted. Additionally, the in vitro test strip meter can be used as back up in case the in vivo system fails, a new sensor is equilibrating, or when the transmitter must be turned off, such as during takeoffs and landings when aboard an airliner. Detailed descriptions of such a continuous glucose monitoring system and its use are provided in U.S. Patent No.
6,175,752, which is incorporated by reference herein in its entirety.
Drug delivery devices, including wholly implantable infusion pumps and pumps that infuse drug through a transcutaneously placed fluid channel such as flexible tubing, are devices that enable the controllable administration of a drug to a user.
Pumps may be under the control or semi-control of a healthcare monitoring device or may be controlled by the user. Examples of such include insulin pumps used by diabetics to administer insulin for glucose control.
The purpose of in vitro or in vivo glucose monitoring, and insulin delivery devices, is to assist people with diabetes in keeping their blood glucose within a predetermined range. If a person's blood glucose level rises too high, hyperglycemia can occur. The short term effects of hyperglycemia can include fatigue, loss of cognitive ability, mood swings, excessive urination, excessive thirst and excessive hunger. Of more immediate concern, if a person's blood glucose level drops too low, hypoglycemia can occur. Like hyperglycemia, symptoms of hypoglycemia also include fatigue and loss of cognitive ability. If unchecked, however, hypoglycemia can quickly lead to loss of consciousness or coma. Some diabetics have little or no symptoms of hypoglycemia, or find it difficult to distinguish between symptoms of hyperglycemia and hypoglycemia. Long term effects of not keeping blood glucose levels within a proper range include health complications such as cardiovascular disease, chronic renal failure, retinal damage which can lead to blindness, nerve damage, impotence, and gangrene with risk of amputation of toes, feet, and even legs. Clearly, proper glucose monitoring and corrective action based on the monitoring is essential for people with diabetes to maintain their health.
Also of importance is compliance to a glucose monitoring regime. Compliance may be particularly difficult with persons who require supervision, e.g., young children or mentally impaired individuals. Compliance may include strict adherence to healthcare provider and/or caregiver provider instructions. If healthcare instructions change, it is necessary that the user be timely notified of such changes.
Likewise, it is important that instructions be readily available in case a person needs to be reminded thereof.
SUMMARY OF THE INVENTION
Before summarizing the invention, it is to be understood that the invention is applicable to in vitro analyte monitoring devices, in vivo analyte monitoring devices, and a drug infusion devices. Unless otherwise indicated, specific reference herein to only one of such devices is only for the sake of brevity and not intended to limit the scope of the invention. Furthermore, the subject invention is described primarily with respect to glucose monitoring devices and insulin infusion pumps, where such descriptions are not intended to limit the scope of the invention. It is to be understood that the subject invention is applicable to any suitable analyte monitoring device and drug infusion device.
According to aspects of some embodiments of the present invention, a medical device (in vitro analyte monitoring device, in vivo analyte monitoring device, drug infusion device) is provided with alert features. These alert features assist a user in maintaining proper analyte levels. Blood glucose is one of many analytes that may be maintained using aspects of the present invention. For each user, an ideal or target analyte range can be established. Above and below this ideal range, upper and lower ranges of moderate concerns, respectively, can also be established. Above the upper range of moderate concern, an upper range of high concern can be established.
Similarly, below the lower range of moderate concern, a lower range of high concern can also be established. By way of example, a user can make in vitro blood glucose measurements, such as with a handheld meter and test strip. In some embodiments of the invention, the user can be alerted by the test meter when a measurement falls within either of the upper or lower ranges of moderate concern. The alert may indicate to the user which of the upper and lower ranges of moderate concern the measurement falls into.
PRIORITY
This application claims priority to US patent application serial no.
11/555,207 filed October 31, 2006, entitled "Infusion Devices And Methods," and is incorporated herein by reference for all purposes.
BACKGROUND OF THE INVENTION
A variety of medical devices are employed to monitor a health condition. For example, devices include those designed to enable a user to manage a health condition based at least in part on the level of analyte in the body. These types of devices include analyte determination devices, drug delivery devices, and the like.
Such analyte devices have become widely used in recent years for people with diabetes. Diabetics have typically measured their blood glucose level by lancing a finger tip or other body location (i.e., alternate site) to draw blood, applying the blood to a disposable test strip in a hand-held meter and allowing the meter and strip to perform an electrochemical test of the blood to determine the current glucose concentration. Such discrete or individual, in vitro tests are typically conducted at least several times per day. Detailed descriptions of such glucose monitoring systems and their use are provided in U.S. Patent No. 7,058,437, issued to TheraSense, Inc., on June 6, 2006, which is incorporated by reference herein in its entirety.
In vivo glucose monitoring devices are designed to provide continuous glucose monitoring. Some of these continuous systems employ a disposable, transcutaneous sensor that is inserted into the skin to measure glucose concentrations in interstitial fluid. A portion of the sensor protrudes from the skin and is coupled with a durable controller and transmitter unit that is attached to the skin with adhesive. A
wireless handheld unit is used in combination with the skin-mounted transmitter and sensor to receive glucose readings periodically, such as once a minute. At a predetermined time interval, such as every three, five or seven days, the disposable sensor is removed and replaced with a fresh sensor which is again coupled to the reusable controller and transmitter unit. With this arrangement, a person with diabetes may continuously monitor their glucose level with the handheld unit. The handheld unit of the in vivo system can also include an in vitro test strip meter for conducting individual tests as described above. The in vitro test strip meter can be used to calibrate the continuous monitoring system each time a new in vivo sensor is implanted. Additionally, the in vitro test strip meter can be used as back up in case the in vivo system fails, a new sensor is equilibrating, or when the transmitter must be turned off, such as during takeoffs and landings when aboard an airliner. Detailed descriptions of such a continuous glucose monitoring system and its use are provided in U.S. Patent No.
6,175,752, which is incorporated by reference herein in its entirety.
Drug delivery devices, including wholly implantable infusion pumps and pumps that infuse drug through a transcutaneously placed fluid channel such as flexible tubing, are devices that enable the controllable administration of a drug to a user.
Pumps may be under the control or semi-control of a healthcare monitoring device or may be controlled by the user. Examples of such include insulin pumps used by diabetics to administer insulin for glucose control.
The purpose of in vitro or in vivo glucose monitoring, and insulin delivery devices, is to assist people with diabetes in keeping their blood glucose within a predetermined range. If a person's blood glucose level rises too high, hyperglycemia can occur. The short term effects of hyperglycemia can include fatigue, loss of cognitive ability, mood swings, excessive urination, excessive thirst and excessive hunger. Of more immediate concern, if a person's blood glucose level drops too low, hypoglycemia can occur. Like hyperglycemia, symptoms of hypoglycemia also include fatigue and loss of cognitive ability. If unchecked, however, hypoglycemia can quickly lead to loss of consciousness or coma. Some diabetics have little or no symptoms of hypoglycemia, or find it difficult to distinguish between symptoms of hyperglycemia and hypoglycemia. Long term effects of not keeping blood glucose levels within a proper range include health complications such as cardiovascular disease, chronic renal failure, retinal damage which can lead to blindness, nerve damage, impotence, and gangrene with risk of amputation of toes, feet, and even legs. Clearly, proper glucose monitoring and corrective action based on the monitoring is essential for people with diabetes to maintain their health.
Also of importance is compliance to a glucose monitoring regime. Compliance may be particularly difficult with persons who require supervision, e.g., young children or mentally impaired individuals. Compliance may include strict adherence to healthcare provider and/or caregiver provider instructions. If healthcare instructions change, it is necessary that the user be timely notified of such changes.
Likewise, it is important that instructions be readily available in case a person needs to be reminded thereof.
SUMMARY OF THE INVENTION
Before summarizing the invention, it is to be understood that the invention is applicable to in vitro analyte monitoring devices, in vivo analyte monitoring devices, and a drug infusion devices. Unless otherwise indicated, specific reference herein to only one of such devices is only for the sake of brevity and not intended to limit the scope of the invention. Furthermore, the subject invention is described primarily with respect to glucose monitoring devices and insulin infusion pumps, where such descriptions are not intended to limit the scope of the invention. It is to be understood that the subject invention is applicable to any suitable analyte monitoring device and drug infusion device.
According to aspects of some embodiments of the present invention, a medical device (in vitro analyte monitoring device, in vivo analyte monitoring device, drug infusion device) is provided with alert features. These alert features assist a user in maintaining proper analyte levels. Blood glucose is one of many analytes that may be maintained using aspects of the present invention. For each user, an ideal or target analyte range can be established. Above and below this ideal range, upper and lower ranges of moderate concerns, respectively, can also be established. Above the upper range of moderate concern, an upper range of high concern can be established.
Similarly, below the lower range of moderate concern, a lower range of high concern can also be established. By way of example, a user can make in vitro blood glucose measurements, such as with a handheld meter and test strip. In some embodiments of the invention, the user can be alerted by the test meter when a measurement falls within either of the upper or lower ranges of moderate concern. The alert may indicate to the user which of the upper and lower ranges of moderate concern the measurement falls into.
According to other aspects of the invention, a medical device (in vitro analyte monitoring device, in vivo analyte monitoring device, drug infusion device) is provided with alarm features. These alarm features also assist a user in maintaining a proper analyte (e.g., blood glucose) level. As described above, upper and lower blood glucose ranges of high concern can be established. In some embodiments of the invention, a test meter can be provided with alarms that warn the user when a measurement falls within either of the upper or lower ranges of high concern. Preferably, the alarm indicates to the user which of the upper and lower ranges of high concern the measurement falls into. Additionally, it is preferable that the alarms indicate a higher level of urgency than do the previously described alerts. Note that a user's analyte level may pass from an ideal range, through a range of moderate concern and into a range of high concern before the user conducts an analyte measurement. In such cases, the user may be provided with an alarm without receiving an alert first.
According to other aspects of the invention, an analyte monitoring system is provided with reminder features. The reminder features also assist a user in maintaining a proper analyte (e.g., glucose) level. Analyte ranges of moderate or high concern can be established, as described above. In some embodiments of the invention, a test meter can have a reminder feature that is triggered when a measurement value falls into a range of moderate or high concern. The reminder can prompt the user after a predetermined period of time to take another analyte measurement to ensure that the analyte level is heading toward or has returned to the ideal range. Such a reminder feature can be particularly helpful since it frees the user from either trying to remember when to retest or from setting an external alarm, if available. For those users that require supervision, such as children, the reminder feature automatically assists the care giver by providing the user with a retest reminder, even when the care giver is not present to perform the task of reminding.
According to various aspects of the invention, the above-described alerts, alarms and reminders can be conveyed to the user visually, such as with a graphical user interface (GUI) or light emitting diode(s) (LED). In one embodiment of the invention, a fixed-segment liquid crystal display (LCD) is used as the GUI, with the value of the analyte measurement appearing in flashing numerals when not in the ideal range. In addition, or in an alternative embodiment, up and down arrow icons can be provided to display when an analyte measurement is in the upper or lower range of moderate and/or high concern. For example, a solid arrow icon can be displayed when the level is in the range of moderate concern, and a flashing arrow can be displayed when the level is in the range of high concern. Different icons can be used depending on whether the level is in the range of moderate or high concern. For instance, an arrow icon having a first size can be displayed when the analyte level is in the range of moderate concern, and a larger or vertically displaced arrow icon can be displayed when the level is in the range of high concern. Alternatively, a horizontal arrow can be displayed when the analyte level is in the ideal range, an arrow inclined upward or downward can be displayed when the level is in the upper or lower range of moderate concern, respectively, and an arrow inclined at a steeper upward or downward angle can be displayed when the level is in the upper or lower range of high concern, respectively. Alternatively, the opposite directions of the above arrows can be used to be indicative the course of action to be taken rather than whether the current level is high or low. For instance, a high analyte level may display a downward pointed arrow to indicate that the user should lower his or her analyte level. In other embodiments, symbols such as +, - and = can be used to indicate high, low and on track readings, respectively. The use of a dot matrix display instead of or in combination with a fixed element display may be employed, e.g., to allow for more flexibility in providing alerts and/or alarms and/or reminders to a user. Text may be shown on the display, with or without accompanying icons, and with or without user feedback, to provide information to the user about a particular alert, alarm and/or reminder. For example, after a test result falling into a range of concern, text may appear explaining the significance of the results, proposing one or more courses of action, and/or indicating that the user should re-test after a certain period of time. After such a period of time has elapsed, a further text message may appear which may include instructions to conduct further tests.
Some text messages may be downloaded or otherwise activated as part of a prescription from a Health Care Provider.
To reduce size and/or cost of a meter, one or more LEDs may be used to convey an alert, alarm or reminder to a user. For instance, a single LED can be illuminated when the analyte measurement is not in the ideal range. The LED can be solid when in the range of moderate concern, and flashing when in the range of high concern.
According to other aspects of the invention, an analyte monitoring system is provided with reminder features. The reminder features also assist a user in maintaining a proper analyte (e.g., glucose) level. Analyte ranges of moderate or high concern can be established, as described above. In some embodiments of the invention, a test meter can have a reminder feature that is triggered when a measurement value falls into a range of moderate or high concern. The reminder can prompt the user after a predetermined period of time to take another analyte measurement to ensure that the analyte level is heading toward or has returned to the ideal range. Such a reminder feature can be particularly helpful since it frees the user from either trying to remember when to retest or from setting an external alarm, if available. For those users that require supervision, such as children, the reminder feature automatically assists the care giver by providing the user with a retest reminder, even when the care giver is not present to perform the task of reminding.
According to various aspects of the invention, the above-described alerts, alarms and reminders can be conveyed to the user visually, such as with a graphical user interface (GUI) or light emitting diode(s) (LED). In one embodiment of the invention, a fixed-segment liquid crystal display (LCD) is used as the GUI, with the value of the analyte measurement appearing in flashing numerals when not in the ideal range. In addition, or in an alternative embodiment, up and down arrow icons can be provided to display when an analyte measurement is in the upper or lower range of moderate and/or high concern. For example, a solid arrow icon can be displayed when the level is in the range of moderate concern, and a flashing arrow can be displayed when the level is in the range of high concern. Different icons can be used depending on whether the level is in the range of moderate or high concern. For instance, an arrow icon having a first size can be displayed when the analyte level is in the range of moderate concern, and a larger or vertically displaced arrow icon can be displayed when the level is in the range of high concern. Alternatively, a horizontal arrow can be displayed when the analyte level is in the ideal range, an arrow inclined upward or downward can be displayed when the level is in the upper or lower range of moderate concern, respectively, and an arrow inclined at a steeper upward or downward angle can be displayed when the level is in the upper or lower range of high concern, respectively. Alternatively, the opposite directions of the above arrows can be used to be indicative the course of action to be taken rather than whether the current level is high or low. For instance, a high analyte level may display a downward pointed arrow to indicate that the user should lower his or her analyte level. In other embodiments, symbols such as +, - and = can be used to indicate high, low and on track readings, respectively. The use of a dot matrix display instead of or in combination with a fixed element display may be employed, e.g., to allow for more flexibility in providing alerts and/or alarms and/or reminders to a user. Text may be shown on the display, with or without accompanying icons, and with or without user feedback, to provide information to the user about a particular alert, alarm and/or reminder. For example, after a test result falling into a range of concern, text may appear explaining the significance of the results, proposing one or more courses of action, and/or indicating that the user should re-test after a certain period of time. After such a period of time has elapsed, a further text message may appear which may include instructions to conduct further tests.
Some text messages may be downloaded or otherwise activated as part of a prescription from a Health Care Provider.
To reduce size and/or cost of a meter, one or more LEDs may be used to convey an alert, alarm or reminder to a user. For instance, a single LED can be illuminated when the analyte measurement is not in the ideal range. The LED can be solid when in the range of moderate concern, and flashing when in the range of high concern.
Different colors in one or more LEDs can indicate different ranges. For instance green can indicate the analyte level is in the ideal range, yellow can indicate the level is in a range of moderate concern and red can indicate the level is in a range of high concern.
Two LEDs can be used to indicate whether the value is high or low (or whether the user's analyte level should be raised or lowered). Three LEDs can be used, for instance with a first LED indicating an analyte level below the ideal range, a second LED
indicating a level in the ideal range, and a third LED indicating a level above the ideal range. Four LEDs can be used to indicate an analyte level in the lower range of high concern, the lower range of moderate concern, the upper range of moderate concern and the upper range of high concern, respectively. A fifth LED can be added to indicate a level in the ideal range.
In addition to or instead of visual indicators of alerts, alarms and reminders, a glucometer constructed according to aspects of the present invention can incorporate audible or physical feedback. Since diabetes can adversely affect a person's eyesight, such forms of user interface can become necessary. In one embodiment of the invention, a meter can emit an audible tone to indicate an analyte reading that is outside of the ideal range. A high tone can be used to indicate a reading that is above the ideal range while a low tone can be used to indicate a reading that is below. A
pulsing or intermittent tone can be used to indicate a reading that is in a range of high concern. A
varying number of pulses and other variations can be employed to indicate what range the analyte reading is in. Similarly, a vibratory signal, such as used in cell phones, can be used with different variations for indicating alerts, alarms and reminders to a user.
According to various aspects of the invention, the above-described alerts, alarms and reminders can be set with default parameters during manufacture, and/or may be settable by a HCP (Health Care Professional such as a Doctor or Certified Diabetes Educator) with levels corresponding to prescribed values for a user, and/or may be user configurable. In one embodiment of the invention, a meter is provided that is set to automatically remind the user to retest after a predetermined period of time, which may be preset or configured, after a test that falls outside of an ideal analyte range. The meter may be configured to allow the user or healthcare professional to disable this feature. In an alternative embodiment, the meter is provided "out of the box" with such a reminder feature disabled, but with provisions to allow the user or healthcare professional to enable it and/or set configuration parameters. A
meter can be provided that allows different reminder parameters depending on whether the underlying analyte measurement is in a range of moderate concern or a range of high concern. In one embodiment, the medical device reminds the user with a first audible signal to retest a first time period (e.g. about 30 minutes) after a test result falling in a range of moderate concern, and reminds the user with a second audible signal to retest after a second time period (e.g. about 15 minutes) after a test result falling in a range of high concern. In certain embodiments, the second audible signal has a higher volume level and/or longer duration than the first audible signal, and the second time period may be shorter than the first time period. In this embodiment, the second audible signal can also be accompanied with a vibratory signal. In this or alternative embodiments, the first and/or second signals can continue or repeat if not acknowledged by the user, such as with the push of a button, or with an actual test being conducted. The parameters of the reminders can also be different based on whether the analyte reading is above or below the ideal range, and/or can vary depending on the actual value of the analyte measurement. For each reminder (alert or alarm) the settings may include, but are not limited to, the analyte value, time to reminder, type of reminder (e.g. visual, audible, vibratory, or a combination thereof), persistence of the reminder (e.g. once, once a minute for n times, or once a minute until acknowledged), and the number of times (n) a persistent reminder will repeat.
According to certain embodiments, a medical device can be provided with alert, alarm and reminder settings, or other healthcare information that can be configured and locked by an authorized individual such as an individual in a supervisory role, e.g., a HCP or caregiver. The information may be locked until an access code is supplied, such as by an authorized individual, e.g., a HCP or a caregiver. Such an arrangement prevents those under the care of a HCP from changing a prescription or those receiving guidance from a caregiver, for instance children, from modifying configuration values.
This prevents intentional or unintentional changes to the configuration values. It also prevents the bypassing of alerts, alarms or reminders, such as when a user wants to engage in behavior that may affect analyte levels, e.g., eat improperly.
According to other aspects, configuration settings may be set through a medical device data port, such as when the medical device is connected to a computer for the uploading and/or downloading of information. In certain embodiments, a medical device may be configured to enable a limited number of individuals, e.g., HCP and/or a caregiver, to set and lock configuration values through the data port.
Application of the inventive aspects described herein is not limited to blood glucose monitoring and/or insulin infusion. For example, analytes may be monitored in other substances such as interstitial fluid. Moreover, monitoring of analytes other than glucose, such as lactate, acetyl choline, amylase, bilirubin, cholesterol, chorionic gonadotropin, creatine kinase (e.g., CK-MB), creatine, DNA, fructosamine, glucose, glutamine, growth hormones, hematocrit, hemoglobin (e.g. HbAlc), hormones, ketones, lactate, oxygen, peroxide, prostate-specific antigen, prothrombin, RNA, thyroid stimulating hormone, and troponin, in samples of body fluid. Meters may also be configured to determine the concentration of drugs, such as, for example, antibiotics (e.g., gentamicin, vancomycin, and the like), digitoxin, digoxin, drugs of abuse, theophylline, warfarin and the like. Such analytes can be monitored in blood, interstitial fluid, saliva, urine and other bodily fluids. It should also be noted that fewer or additional analyte measurement ranges from those described herein can be used.
This includes not using ranges at all, but instead using, e.g., absolute values, formulas, lookup tables or similar concepts know to those skilled in the art to determine if or what type of alert, alarm, reminder or other indication should be made to the user for a particular analyte measurement result.
BRIEF DESCRIPTION OF THE DRAWINGS
Each of the figures diagrammatically illustrates aspects of the invention. Of these:
Fig. 1 is plan view showing an exemplary embodiment of an analyte monitoring system, such as a glucometer system, constructed according to aspects of the present invention;
Fig. 2 is a block diagram of an exemplary embodiment of an insulin delivery device;
Fig. 3 is a block diagram illustrating an exemplary embodiment of an insulin therapy management system that incorporates the delivery device of Fig. 2;
Two LEDs can be used to indicate whether the value is high or low (or whether the user's analyte level should be raised or lowered). Three LEDs can be used, for instance with a first LED indicating an analyte level below the ideal range, a second LED
indicating a level in the ideal range, and a third LED indicating a level above the ideal range. Four LEDs can be used to indicate an analyte level in the lower range of high concern, the lower range of moderate concern, the upper range of moderate concern and the upper range of high concern, respectively. A fifth LED can be added to indicate a level in the ideal range.
In addition to or instead of visual indicators of alerts, alarms and reminders, a glucometer constructed according to aspects of the present invention can incorporate audible or physical feedback. Since diabetes can adversely affect a person's eyesight, such forms of user interface can become necessary. In one embodiment of the invention, a meter can emit an audible tone to indicate an analyte reading that is outside of the ideal range. A high tone can be used to indicate a reading that is above the ideal range while a low tone can be used to indicate a reading that is below. A
pulsing or intermittent tone can be used to indicate a reading that is in a range of high concern. A
varying number of pulses and other variations can be employed to indicate what range the analyte reading is in. Similarly, a vibratory signal, such as used in cell phones, can be used with different variations for indicating alerts, alarms and reminders to a user.
According to various aspects of the invention, the above-described alerts, alarms and reminders can be set with default parameters during manufacture, and/or may be settable by a HCP (Health Care Professional such as a Doctor or Certified Diabetes Educator) with levels corresponding to prescribed values for a user, and/or may be user configurable. In one embodiment of the invention, a meter is provided that is set to automatically remind the user to retest after a predetermined period of time, which may be preset or configured, after a test that falls outside of an ideal analyte range. The meter may be configured to allow the user or healthcare professional to disable this feature. In an alternative embodiment, the meter is provided "out of the box" with such a reminder feature disabled, but with provisions to allow the user or healthcare professional to enable it and/or set configuration parameters. A
meter can be provided that allows different reminder parameters depending on whether the underlying analyte measurement is in a range of moderate concern or a range of high concern. In one embodiment, the medical device reminds the user with a first audible signal to retest a first time period (e.g. about 30 minutes) after a test result falling in a range of moderate concern, and reminds the user with a second audible signal to retest after a second time period (e.g. about 15 minutes) after a test result falling in a range of high concern. In certain embodiments, the second audible signal has a higher volume level and/or longer duration than the first audible signal, and the second time period may be shorter than the first time period. In this embodiment, the second audible signal can also be accompanied with a vibratory signal. In this or alternative embodiments, the first and/or second signals can continue or repeat if not acknowledged by the user, such as with the push of a button, or with an actual test being conducted. The parameters of the reminders can also be different based on whether the analyte reading is above or below the ideal range, and/or can vary depending on the actual value of the analyte measurement. For each reminder (alert or alarm) the settings may include, but are not limited to, the analyte value, time to reminder, type of reminder (e.g. visual, audible, vibratory, or a combination thereof), persistence of the reminder (e.g. once, once a minute for n times, or once a minute until acknowledged), and the number of times (n) a persistent reminder will repeat.
According to certain embodiments, a medical device can be provided with alert, alarm and reminder settings, or other healthcare information that can be configured and locked by an authorized individual such as an individual in a supervisory role, e.g., a HCP or caregiver. The information may be locked until an access code is supplied, such as by an authorized individual, e.g., a HCP or a caregiver. Such an arrangement prevents those under the care of a HCP from changing a prescription or those receiving guidance from a caregiver, for instance children, from modifying configuration values.
This prevents intentional or unintentional changes to the configuration values. It also prevents the bypassing of alerts, alarms or reminders, such as when a user wants to engage in behavior that may affect analyte levels, e.g., eat improperly.
According to other aspects, configuration settings may be set through a medical device data port, such as when the medical device is connected to a computer for the uploading and/or downloading of information. In certain embodiments, a medical device may be configured to enable a limited number of individuals, e.g., HCP and/or a caregiver, to set and lock configuration values through the data port.
Application of the inventive aspects described herein is not limited to blood glucose monitoring and/or insulin infusion. For example, analytes may be monitored in other substances such as interstitial fluid. Moreover, monitoring of analytes other than glucose, such as lactate, acetyl choline, amylase, bilirubin, cholesterol, chorionic gonadotropin, creatine kinase (e.g., CK-MB), creatine, DNA, fructosamine, glucose, glutamine, growth hormones, hematocrit, hemoglobin (e.g. HbAlc), hormones, ketones, lactate, oxygen, peroxide, prostate-specific antigen, prothrombin, RNA, thyroid stimulating hormone, and troponin, in samples of body fluid. Meters may also be configured to determine the concentration of drugs, such as, for example, antibiotics (e.g., gentamicin, vancomycin, and the like), digitoxin, digoxin, drugs of abuse, theophylline, warfarin and the like. Such analytes can be monitored in blood, interstitial fluid, saliva, urine and other bodily fluids. It should also be noted that fewer or additional analyte measurement ranges from those described herein can be used.
This includes not using ranges at all, but instead using, e.g., absolute values, formulas, lookup tables or similar concepts know to those skilled in the art to determine if or what type of alert, alarm, reminder or other indication should be made to the user for a particular analyte measurement result.
BRIEF DESCRIPTION OF THE DRAWINGS
Each of the figures diagrammatically illustrates aspects of the invention. Of these:
Fig. 1 is plan view showing an exemplary embodiment of an analyte monitoring system, such as a glucometer system, constructed according to aspects of the present invention;
Fig. 2 is a block diagram of an exemplary embodiment of an insulin delivery device;
Fig. 3 is a block diagram illustrating an exemplary embodiment of an insulin therapy management system that incorporates the delivery device of Fig. 2;
Fig. 4 is a detail example of various alert and alarm displays, one of which is shown in the system of Fig. 1;
Fig. 5 is a graph depicting an example of how the glucose level of a user might vary over the course of a portion of a day;
Fig. 6 is a graph depicting the glucose levels shown in Fig. 3 with testing points added, some of which occur as a result of a reminder (alert or alarm);
Figs. 7A and 7B show exemplary embodiments of a medical device with restrictive user control;
Fig. 8 shows the medical device of Fig. 7B connected to an exemplary embodiment of a data management system; and Fig. 9 shows an exemplary embodiment of application software that may run on the data management system of Fig. 8.
Variation of the invention from that shown in the figures is contemplated.
DETAILED DESCRIPTION
The following description focuses on one variation of the present invention.
The variation of the invention is to be taken as a non-limiting example. It is to be understood that the invention is not limited to particular variation(s) set forth and may, of course, vary. Changes may be made to the invention described and equivalents may be substituted (both presently known and future-developed) without departing from the true spirit and scope of the invention. In addition, modifications may be made to adapt a particular situation, material, composition of matter, process, process act(s) or step(s) to the objective(s), spirit or scope of the present invention.
Fig. 1 shows a top view of an exemplary analyte medical system 10, e.g., a glucometer system in this particular embodiment. Analyte medical device 10 may be an electrochemical or optical system. System 10 includes a handheld meter 12 and disposable test strip 14. Test strip 14 can be inserted into or removed from test strip port 16 of meter 12 for physical and electrical interconnection therewith.
Meter 12 includes an LCD display 18 for displaying information to the meter user, and buttons 20, 22 and 24 for receiving input from the user.
In general, to take a blood glucose measurement with meter 12, a user inserts a new test strip 14 into port 16 of meter 12. Either before of after strip insertion into the meter, a user then lances a fingertip or other part of the body (i.e.
alternate site) to draw a small drop of blood 26 to the surface of the skin. The meter and strip are positioned over the drop of blood 26 so that one of the sample chamber ends 28 is touching the drop of blood 26. While this particular example teaches the use of a side-fill strip, it should be noted that an end-fill, top-fill or other type of test strip may be utilized.
Moreover, the analyte testing need not use a test strip at all. For instance, certain test meters may utilize a rotary test wheel for making multiple measurements, rather than individual test strips. In the present example, surface tension (wicking) automatically draws a small amount of blood 26 into the sample chamber and an electrochemical test is automatically performed by meter 12 to determine the glucose concentration in the blood 26. The glucose leve130 is then displayed on meter 12. As noted above, the subject invention is also applicable to continuous analyte monitoring systems and drug infusion devices.
The present invention may also find use with infusion systems for infusing an agent to a user such as drug infusion systems, e.g., insulin infusion systems.
Such infusion systems may be wholly implantable systems or external systems.
External infusion devices are typically connected to an infusion set which includes a cannula that is placed transcutaneously through the skin of the patient to infuse a select dosage of an agent. For example, external insulin infusion devices are typically connected to an infusion set which includes a cannula that is placed transcutaneously through the skin of the patient to infuse a select dosage of insulin based on the infusion device's programmed basal rates or any other infusion rates as prescribed by the patient's HCP.
A user may be able to control the insulin pump device to administer additional doses of insulin during the course of wearing and operating the infusion device such as for, administering a carbohydrate bolus prior to a meal. Certain infusion devices may a include food database that has associated therewith, an amount of carbohydrate, so that the patient may better estimate the level of insulin dosage needed for, for example, calculating a bolus amount.
Fig. 2 is a block diagram of an exemplary embodiment of an insulin delivery for use with the present invention. Insulin delivery device 620 in one embodiment includes a processor 710 operatively coupled to a memory unit 740, an input unit 720, a display unit 730, an output unit 760, and a fluid delivery unit 750. In one embodiment, the processor 710 includes a microprocessor that is configured to and capable of controlling the functions of the insulin delivery device 620 by controlling and/or accessing each of the various components of the insulin delivery device 620.
In one embodiment, multiple processors may be provided as safety measure and to provide redundancy in case of a single processor failure. Moreover, processing capabilities may be shared between multiple processor units within the insulin delivery device 620 such that pump functions and/or control maybe performed faster and more accurately.
Input unit 720 operatively coupled to the processor 710 may include a jog dial, a key pad buttons, a touch pad screen, or any other suitable input mechanism for providing input commands to the insulin delivery device 620. More specifically, in case of a jog dial input device, or a touch pad screen, for example, the patient or user of the insulin delivery device 620 may manipulate the respective jog dial or touch pad in conjunction with the display unit 730 which performs as both a data input and output units. The display unit 730 may include a touch sensitive screen, an LCD
screen, or any other types of suitable display unit for the insulin delivery device 620 that is configured to display alphanumeric data as well as pictorial information such as icons associated with one or more predefined states of the insulin delivery device 620, or graphical representation of data such as trend charts and graphs associated with the insulin infusion rates, trend data of monitored glucose levels over a period of time, or textual notification to the patients.
Output unit 760 operatively coupled to the processor 710 may include audible alarm including one or more tones and/or preprogrammed or programmable tunes or audio clips, or vibratory alert features having one or more pre-programmed or programmable vibratory alert levels. In one embodiment, the vibratory alert may also assist in priming the infusion tubing to minimize the potential for air or other undesirable material in the infusion tubing. Also shown is the fluid delivery unit 750 which is operatively coupled to the processor 710 and configured to deliver the insulin doses or amounts to the patient from the insulin reservoir or any other types of suitable containment for insulin to be delivered (not shown) in the insulin delivery device 620 via an infusion set coupled to a subcutaneously positioned cannula under the skin of the patient.
Fig. 5 is a graph depicting an example of how the glucose level of a user might vary over the course of a portion of a day;
Fig. 6 is a graph depicting the glucose levels shown in Fig. 3 with testing points added, some of which occur as a result of a reminder (alert or alarm);
Figs. 7A and 7B show exemplary embodiments of a medical device with restrictive user control;
Fig. 8 shows the medical device of Fig. 7B connected to an exemplary embodiment of a data management system; and Fig. 9 shows an exemplary embodiment of application software that may run on the data management system of Fig. 8.
Variation of the invention from that shown in the figures is contemplated.
DETAILED DESCRIPTION
The following description focuses on one variation of the present invention.
The variation of the invention is to be taken as a non-limiting example. It is to be understood that the invention is not limited to particular variation(s) set forth and may, of course, vary. Changes may be made to the invention described and equivalents may be substituted (both presently known and future-developed) without departing from the true spirit and scope of the invention. In addition, modifications may be made to adapt a particular situation, material, composition of matter, process, process act(s) or step(s) to the objective(s), spirit or scope of the present invention.
Fig. 1 shows a top view of an exemplary analyte medical system 10, e.g., a glucometer system in this particular embodiment. Analyte medical device 10 may be an electrochemical or optical system. System 10 includes a handheld meter 12 and disposable test strip 14. Test strip 14 can be inserted into or removed from test strip port 16 of meter 12 for physical and electrical interconnection therewith.
Meter 12 includes an LCD display 18 for displaying information to the meter user, and buttons 20, 22 and 24 for receiving input from the user.
In general, to take a blood glucose measurement with meter 12, a user inserts a new test strip 14 into port 16 of meter 12. Either before of after strip insertion into the meter, a user then lances a fingertip or other part of the body (i.e.
alternate site) to draw a small drop of blood 26 to the surface of the skin. The meter and strip are positioned over the drop of blood 26 so that one of the sample chamber ends 28 is touching the drop of blood 26. While this particular example teaches the use of a side-fill strip, it should be noted that an end-fill, top-fill or other type of test strip may be utilized.
Moreover, the analyte testing need not use a test strip at all. For instance, certain test meters may utilize a rotary test wheel for making multiple measurements, rather than individual test strips. In the present example, surface tension (wicking) automatically draws a small amount of blood 26 into the sample chamber and an electrochemical test is automatically performed by meter 12 to determine the glucose concentration in the blood 26. The glucose leve130 is then displayed on meter 12. As noted above, the subject invention is also applicable to continuous analyte monitoring systems and drug infusion devices.
The present invention may also find use with infusion systems for infusing an agent to a user such as drug infusion systems, e.g., insulin infusion systems.
Such infusion systems may be wholly implantable systems or external systems.
External infusion devices are typically connected to an infusion set which includes a cannula that is placed transcutaneously through the skin of the patient to infuse a select dosage of an agent. For example, external insulin infusion devices are typically connected to an infusion set which includes a cannula that is placed transcutaneously through the skin of the patient to infuse a select dosage of insulin based on the infusion device's programmed basal rates or any other infusion rates as prescribed by the patient's HCP.
A user may be able to control the insulin pump device to administer additional doses of insulin during the course of wearing and operating the infusion device such as for, administering a carbohydrate bolus prior to a meal. Certain infusion devices may a include food database that has associated therewith, an amount of carbohydrate, so that the patient may better estimate the level of insulin dosage needed for, for example, calculating a bolus amount.
Fig. 2 is a block diagram of an exemplary embodiment of an insulin delivery for use with the present invention. Insulin delivery device 620 in one embodiment includes a processor 710 operatively coupled to a memory unit 740, an input unit 720, a display unit 730, an output unit 760, and a fluid delivery unit 750. In one embodiment, the processor 710 includes a microprocessor that is configured to and capable of controlling the functions of the insulin delivery device 620 by controlling and/or accessing each of the various components of the insulin delivery device 620.
In one embodiment, multiple processors may be provided as safety measure and to provide redundancy in case of a single processor failure. Moreover, processing capabilities may be shared between multiple processor units within the insulin delivery device 620 such that pump functions and/or control maybe performed faster and more accurately.
Input unit 720 operatively coupled to the processor 710 may include a jog dial, a key pad buttons, a touch pad screen, or any other suitable input mechanism for providing input commands to the insulin delivery device 620. More specifically, in case of a jog dial input device, or a touch pad screen, for example, the patient or user of the insulin delivery device 620 may manipulate the respective jog dial or touch pad in conjunction with the display unit 730 which performs as both a data input and output units. The display unit 730 may include a touch sensitive screen, an LCD
screen, or any other types of suitable display unit for the insulin delivery device 620 that is configured to display alphanumeric data as well as pictorial information such as icons associated with one or more predefined states of the insulin delivery device 620, or graphical representation of data such as trend charts and graphs associated with the insulin infusion rates, trend data of monitored glucose levels over a period of time, or textual notification to the patients.
Output unit 760 operatively coupled to the processor 710 may include audible alarm including one or more tones and/or preprogrammed or programmable tunes or audio clips, or vibratory alert features having one or more pre-programmed or programmable vibratory alert levels. In one embodiment, the vibratory alert may also assist in priming the infusion tubing to minimize the potential for air or other undesirable material in the infusion tubing. Also shown is the fluid delivery unit 750 which is operatively coupled to the processor 710 and configured to deliver the insulin doses or amounts to the patient from the insulin reservoir or any other types of suitable containment for insulin to be delivered (not shown) in the insulin delivery device 620 via an infusion set coupled to a subcutaneously positioned cannula under the skin of the patient.
Memory unit 740 may include one or more of a random access memory (RAM), read only memory (ROM), or any other types of data storage units that is configured to store data as well as program instructions for access by the processor 710 and execution to control the insulin delivery device 620 and/or to perform data processing based on data received from, e.g., an analyte monitoring system 610, a remote termina1640 (HCP or caregiver), the patient 630 or any other data input source (see for example Fig .3).
Fig. 3 is a block diagram illustrating an insulin therapy management system that includes an insulin infusion device and an analyte monitoring system. The insulin therapy management system 600 includes an analyte monitoring system 610 operatively coupled to an insulin delivery device 620, which may be in turn, operatively coupled to a remote termina1640. Analyte monitoring system 610 is, in one embodiment, coupled to the patient 630 so as to monitor or measure the analyte levels of the patient. Moreover, the insulin delivery device 620 is coupled to the patient using, for example, and infusion set and tubing connected to a cannula (not shown) that is placed transcutaneously through the skin of the patient so as to infuse medication such as, for example, insulin, to the patient.
In one embodiment, the analyte monitoring system 610 may include one or more analyte sensors subcutaneously positioned such that at least a portion of the analyte sensors are maintained in fluid contact with the patient's analytes.
The analyte sensors may include, but not limited to short term subcutaneous analyte sensors or transdermal analyte sensors, for example, which are configured to detect analyte levels of a patient over a predetermined time period, and after which, a replacement of the sensors is necessary.
The one or more analyte sensors of the analyte monitoring system 610 is coupled to a respective one or more of a data transmitter unit which is configured to receive one or more signals from the respective analyte sensors corresponding to the detected analyte levels of the patient, and to transmit the information corresponding to the detected analyte levels to a receiver device, and/or insulin delivery device 620.
That is, over a communication link, the transmitter units may be configured to transmit data associated with the detected analyte levels periodically, and/or intermittently and repeatedly to one or more other devices such as the insulin delivery device and/or the remote termina1640 for further data processing and analysis. The transmitter units of the analyte monitoring system 610 may in one embodiment configured to transmit the analyte related data substantially in real time to the insulin delivery device 620 and/or the remote termina1640 after receiving it from the corresponding analyte sensors such that the analyte level such as glucose level of the patient 630 may be monitored in real time.
The transmitter units of the analyte monitoring system 610 may be configured to directly communicate with one or more of the remote termina1640 or the insulin delivery device 620. Furthermore, within the scope of the present invention, additional devices may be provided for communication in the insulin therapy management system 600 including additional receiver/data processing unit, remote terminals (such as a HCP
terminal and/or a bedside terminal in a hospital environment, for example).
The insulin delivery device 620 may include in one embodiment, but is not limited to, an external infusion device such as an external insulin infusion pump, an implantable pump, a pen-type insulin injector device, a patch pump, an inhalable infusion device for nasal insulin delivery, or any other type of suitable delivery system.
In one embodiment, the analyte monitoring system 610 includes a strip port configured to receive a test strip for capillary blood glucose testing. In one aspect, the glucose level measured using the test strip may in addition, be configured to provide periodic calibration of the analyte sensors of the analyte monitoring system 610 to assure and improve the accuracy of the analyte levels detected by the analyte sensors.
Exemplary in vitro and in vivo analyte monitoring system and drug infusion systems that may be adapted for the present invention include, but are not limited to, those described in U.S. Patent Nos. 6,175,752; 6,329,161; 6,284,478;
6,916,159;
7,041,468; 7,077,328, and U.S. Patent Application Serial Nos. 11/383,945;
11/365,168;
11/386,915; 11/396,181; 11/396,182, and elsewhere, the disclosures of which are herein incorporated in their entirety by reference.
According to aspects of the present invention, an alert and/or alarm 32 can also be shown on display 18 indicating, for example, whether the current measurement falls within a predetermined range, such as an ideal glucose range, an upper or lower range of moderate concern or an upper or lower range of high concern.
Fig. 3 is a block diagram illustrating an insulin therapy management system that includes an insulin infusion device and an analyte monitoring system. The insulin therapy management system 600 includes an analyte monitoring system 610 operatively coupled to an insulin delivery device 620, which may be in turn, operatively coupled to a remote termina1640. Analyte monitoring system 610 is, in one embodiment, coupled to the patient 630 so as to monitor or measure the analyte levels of the patient. Moreover, the insulin delivery device 620 is coupled to the patient using, for example, and infusion set and tubing connected to a cannula (not shown) that is placed transcutaneously through the skin of the patient so as to infuse medication such as, for example, insulin, to the patient.
In one embodiment, the analyte monitoring system 610 may include one or more analyte sensors subcutaneously positioned such that at least a portion of the analyte sensors are maintained in fluid contact with the patient's analytes.
The analyte sensors may include, but not limited to short term subcutaneous analyte sensors or transdermal analyte sensors, for example, which are configured to detect analyte levels of a patient over a predetermined time period, and after which, a replacement of the sensors is necessary.
The one or more analyte sensors of the analyte monitoring system 610 is coupled to a respective one or more of a data transmitter unit which is configured to receive one or more signals from the respective analyte sensors corresponding to the detected analyte levels of the patient, and to transmit the information corresponding to the detected analyte levels to a receiver device, and/or insulin delivery device 620.
That is, over a communication link, the transmitter units may be configured to transmit data associated with the detected analyte levels periodically, and/or intermittently and repeatedly to one or more other devices such as the insulin delivery device and/or the remote termina1640 for further data processing and analysis. The transmitter units of the analyte monitoring system 610 may in one embodiment configured to transmit the analyte related data substantially in real time to the insulin delivery device 620 and/or the remote termina1640 after receiving it from the corresponding analyte sensors such that the analyte level such as glucose level of the patient 630 may be monitored in real time.
The transmitter units of the analyte monitoring system 610 may be configured to directly communicate with one or more of the remote termina1640 or the insulin delivery device 620. Furthermore, within the scope of the present invention, additional devices may be provided for communication in the insulin therapy management system 600 including additional receiver/data processing unit, remote terminals (such as a HCP
terminal and/or a bedside terminal in a hospital environment, for example).
The insulin delivery device 620 may include in one embodiment, but is not limited to, an external infusion device such as an external insulin infusion pump, an implantable pump, a pen-type insulin injector device, a patch pump, an inhalable infusion device for nasal insulin delivery, or any other type of suitable delivery system.
In one embodiment, the analyte monitoring system 610 includes a strip port configured to receive a test strip for capillary blood glucose testing. In one aspect, the glucose level measured using the test strip may in addition, be configured to provide periodic calibration of the analyte sensors of the analyte monitoring system 610 to assure and improve the accuracy of the analyte levels detected by the analyte sensors.
Exemplary in vitro and in vivo analyte monitoring system and drug infusion systems that may be adapted for the present invention include, but are not limited to, those described in U.S. Patent Nos. 6,175,752; 6,329,161; 6,284,478;
6,916,159;
7,041,468; 7,077,328, and U.S. Patent Application Serial Nos. 11/383,945;
11/365,168;
11/386,915; 11/396,181; 11/396,182, and elsewhere, the disclosures of which are herein incorporated in their entirety by reference.
According to aspects of the present invention, an alert and/or alarm 32 can also be shown on display 18 indicating, for example, whether the current measurement falls within a predetermined range, such as an ideal glucose range, an upper or lower range of moderate concern or an upper or lower range of high concern.
Referring now to Fig. 4, a further example of alert and alarm displays 32 is shown. A steeply downwardly inclined arrow 34 (e.g. from about -60 to about -degrees) can be used to indicate a glucose reading in a lower range of high concern, such as below 50 mg/dL. A moderately downwardly inclined arrow 36 (e.g. from about -30 to about -45 degrees) can be used to indicate a glucose reading in a lower range of moderate concern, such as about 50 mg/dL to about 75 mg/dL. A horizontal arrow (e.g. about 0 degrees) can be used to indicate a glucose reading in an ideal range, such as about 75 mg/dL to about 175 mg/dL. A moderately upwardly inclined arrow 40 (e.g.
about 30 or about 45 degrees) can be used to indicate a glucose reading in an upper range of moderate concern, such as about 175 mg/dL to about 250 mg/dL.
Finally, a steeply upwardly inclined arrow 42 (e.g. from about 60 to about 90 degrees) can be used to indicate a glucose reading in an upper range of high concern, such as above about 250 mg/dL. As previously indicated above, various other visual elements, and/or audible or physical indicators can be used to provide the user with an alert or an alarm.
Referring now to Fig. 5, an example of blood glucose values for a user is shown. Curve 100 depicts how the user's blood glucose might change with time over a portion of a day. In this example, the ideal range for the user is about 75 mg/dL to about 175 mg/dL, shown with reference numeral 110 and bounded by dashed lines and 114. The ranges of moderate concern are about 50 mg/dL to about 75 mg/dL
(lower alert zone 116, bounded by dashed lines 112 and 118) and about 175 mg/dL to about 250 mg/dL (upper alert zone 120, bounded by dashed lines 114 and 122).
The ranges of high concern are below about 50 mg/dL (lower alarm zone 124, below dashed line 118) and above about 250 mg/dL (upper alarm zone 126, above dashed line 122.
In Fig. 5 the glucose values (100) begin at about 150 mg/dL, rise to about 195 mg/dL (101), fall to about 155 mg/dL (102), rise to about 270 mg/dL (103), fall to about 60 mg/dL (104), rise to about 90 mg/dL (105), fall to about 40 mg/dL
(106), and end at about 100 mg/dL.
Fig. 6 shows the same blood glucose values 100 as Fig. 5 but adds the testing that was performed by that user, some of which occurs as a result of a reminder (alert and/or alarm and/or reminder). For example, after a light meal (snack) the user tests with a reading of 193 mg/dL (201) that falls in the upper alert zone (120).
This reading may cause meter 12 to generate an alert to the user, e.g., flashing display, beep, or the like, that his or her glucose is in an upper level of moderate concern, as previously described above. The meter may alert the user substantially immediately after the determination of the reading in the upper alert zone, or sometime thereafter as described below. Regardless of whether the user is notified substantially immediately of a reading in an alert zone (or other zone of concern as described herein), the meter may also be configured to remind the user to perform a re-test after a predetermined amount of time following a reading in a zone of importance (alarm zone or alert zone).
For example, after the above-described meter reading in upper alert zone 120, a meter reminder may notify the user to perform a test after a predetermined amount of time, e.g., about 5 minutes, e.g., about 10 minutes, e.g., about 20 minutes, e.g., about 30 minutes, etc., and may periodically remind a user until a test is performed or until the reminder is cleared by the user. For example, the user may respond to the reading and alert (if alerted) with modest therapy and some time later (e.g., about 30 minutes), a reminder prompts the user to test, resulting in a reading of 160 mg/dL (202) that falls in the ideal zone (110).
Later, after a large meal the user tests with a reading of 268 mg/dL (203) that falls in the upper alarm zone (126). This reading causes meter 12 to generate an alarm to the user that his or her glucose is in an upper level of high concern. The user responds to the reading with an appropriate therapy and some time later (e.g.
minutes), a reminder prompts the user to test, resulting in a reading of 232 mg/dL (204) that falls in the upper alert zone (120). This reading causes meter 12 to generate an alert to the user that his or her glucose is in an upper level of moderate concern. The user may note that the previous therapy was appropriate and again, some time later (e.g.
minutes), a reminder prompts the user to test again, resulting in a reading of 25 mg/dL (205) that falls in the ideal zone (110) and confirms the previous therapy was appropriate.
Still later, after having exercised but not having eaten the user feels slightly symptomatic and tests with a reading of 61 mg/dL (206) that falls in the lower alert zone (116). This reading causes meter 12 to generate an alert to the user that his or her 30 glucose is in a lower level of moderate concern. The user responds by eating a light meal (snack) and some time later (e.g. 25 minutes), a reminder prompts the user to test, resulting in a reading of 81 mg/dL (207) that falls in the ideal zone (110).
about 30 or about 45 degrees) can be used to indicate a glucose reading in an upper range of moderate concern, such as about 175 mg/dL to about 250 mg/dL.
Finally, a steeply upwardly inclined arrow 42 (e.g. from about 60 to about 90 degrees) can be used to indicate a glucose reading in an upper range of high concern, such as above about 250 mg/dL. As previously indicated above, various other visual elements, and/or audible or physical indicators can be used to provide the user with an alert or an alarm.
Referring now to Fig. 5, an example of blood glucose values for a user is shown. Curve 100 depicts how the user's blood glucose might change with time over a portion of a day. In this example, the ideal range for the user is about 75 mg/dL to about 175 mg/dL, shown with reference numeral 110 and bounded by dashed lines and 114. The ranges of moderate concern are about 50 mg/dL to about 75 mg/dL
(lower alert zone 116, bounded by dashed lines 112 and 118) and about 175 mg/dL to about 250 mg/dL (upper alert zone 120, bounded by dashed lines 114 and 122).
The ranges of high concern are below about 50 mg/dL (lower alarm zone 124, below dashed line 118) and above about 250 mg/dL (upper alarm zone 126, above dashed line 122.
In Fig. 5 the glucose values (100) begin at about 150 mg/dL, rise to about 195 mg/dL (101), fall to about 155 mg/dL (102), rise to about 270 mg/dL (103), fall to about 60 mg/dL (104), rise to about 90 mg/dL (105), fall to about 40 mg/dL
(106), and end at about 100 mg/dL.
Fig. 6 shows the same blood glucose values 100 as Fig. 5 but adds the testing that was performed by that user, some of which occurs as a result of a reminder (alert and/or alarm and/or reminder). For example, after a light meal (snack) the user tests with a reading of 193 mg/dL (201) that falls in the upper alert zone (120).
This reading may cause meter 12 to generate an alert to the user, e.g., flashing display, beep, or the like, that his or her glucose is in an upper level of moderate concern, as previously described above. The meter may alert the user substantially immediately after the determination of the reading in the upper alert zone, or sometime thereafter as described below. Regardless of whether the user is notified substantially immediately of a reading in an alert zone (or other zone of concern as described herein), the meter may also be configured to remind the user to perform a re-test after a predetermined amount of time following a reading in a zone of importance (alarm zone or alert zone).
For example, after the above-described meter reading in upper alert zone 120, a meter reminder may notify the user to perform a test after a predetermined amount of time, e.g., about 5 minutes, e.g., about 10 minutes, e.g., about 20 minutes, e.g., about 30 minutes, etc., and may periodically remind a user until a test is performed or until the reminder is cleared by the user. For example, the user may respond to the reading and alert (if alerted) with modest therapy and some time later (e.g., about 30 minutes), a reminder prompts the user to test, resulting in a reading of 160 mg/dL (202) that falls in the ideal zone (110).
Later, after a large meal the user tests with a reading of 268 mg/dL (203) that falls in the upper alarm zone (126). This reading causes meter 12 to generate an alarm to the user that his or her glucose is in an upper level of high concern. The user responds to the reading with an appropriate therapy and some time later (e.g.
minutes), a reminder prompts the user to test, resulting in a reading of 232 mg/dL (204) that falls in the upper alert zone (120). This reading causes meter 12 to generate an alert to the user that his or her glucose is in an upper level of moderate concern. The user may note that the previous therapy was appropriate and again, some time later (e.g.
minutes), a reminder prompts the user to test again, resulting in a reading of 25 mg/dL (205) that falls in the ideal zone (110) and confirms the previous therapy was appropriate.
Still later, after having exercised but not having eaten the user feels slightly symptomatic and tests with a reading of 61 mg/dL (206) that falls in the lower alert zone (116). This reading causes meter 12 to generate an alert to the user that his or her 30 glucose is in a lower level of moderate concern. The user responds by eating a light meal (snack) and some time later (e.g. 25 minutes), a reminder prompts the user to test, resulting in a reading of 81 mg/dL (207) that falls in the ideal zone (110).
Yet later still, the user feels symptomatic and tests with a reading of 41 mg/dL
(208) that falls in the lower alarm zone (124). This reading causes meter 12 to generate an alarm indicating that the glucose level is in a lower level of high concern. The user responds by eating a modest meal and some time later (e.g. 15 minutes), a reminder prompts the user to test, resulting in a reading of 63 mg/dL (209) that falls in the lower alert zone (116). This reading causes meter 12 to generate an alert indicating that the glucose level is now in a lower level of moderate concern. The user may note that the previous therapy (meal) was appropriate or may eat a small amount (snack) and again some time later (e.g. 25 minutes), a reminder prompts the user to test, resulting in a reading of 99 mg/dL (210) that falls in the ideal zone (110) and confirms the course of therapy was appropriate.
It should be noted that in this example, tests 201, 203, 206 and 208 were initiated by the user based on events known by the user to cause changes in blood glucose, or based on symptoms experienced by the user. More importantly, the user was prompted to perform tests 202, 204, 205, 207, 209 and 210 by a meter constructed according to aspects of the present invention. These prompts or timed reminders assist the user in performing appropriate tests in a timely manner. These tests in turn facilitate the user's important goal of keeping his or her blood glucose level in the ideal zone 110 to maintain the user's short-term and long-term health.
Embodiments also include supervisor-controllable, including person-restrictive (e.g., user-restrictive), medical devices. Configurations of a medical devices may be settable and/or lockable by a supervisor (e.g., a HCP, parent or guardian, caregiver, or the like), e.g., remotely or by direct action (e.g., using a user interface of the device, or the like). For example, certain configurations of a medical device may be settable and/or lockable by a first person (e.g., a HCP) having a first access level (e.g., full access such as full Read/Write permission) and certain configurations that may be settable and/or lockable by a second person (e.g., a caregiver) having a second access level (e.g., limited Read/Write permission). The medical device may be settable and/or lockable by a third person (e.g., a user under the supervision of the first and second persons) having a third access level (e.g., further limited, e.g., Read only -including no rights to modify previously inputted data). Any number of persons may have certain or limited access rights to a medical device. For example, certain embodiments include medical devices having certain configurations settable and/or lockable by a HCP and certain other features settable and/or lockable by a caregiver. A user may be completely restricted from modifying the configurations set by the HCP and/or caregiver.
Configurations may be access controlled with an access code (e.g., password protected, voice authentication, USB token protected, or other manner of authenticating a user) to allow access permissions for a specific individual, medical device, computer, or group of individuals. When permission is set, the type and level of access granted to an individual, computer, or group is granted. For example, various degrees of, e.g., Read and Write and View permissions may be granted to different persons, as described above.
Different codes may provide different rights. For example an HCP code may enable a HCP to enter prescriptive information and/or delete and/or modify stored prescriptive ("Rx") information, where prescriptive information is broadly defined relevant information prescribed by a HCP. Prescriptive information may include patient-specific data and may include but is not limited to, one or a plurality of basal rates, insulin ideal analyte ranges, alert and alarm thresholds, medication type (e.g., insulin type), medication dose including total daily dose (e.g., total daily insulin dosage), drug sensitivity (e.g., insulin sensitivity), when to take a medication, how to take a medication, when to treat a condition, how to treat a condition, when to elevate concerns to a HCP or caregiver, reminder schemes (e.g., setting times of reminders), etc. The above is not an exhaustive list, e.g., for treating diabetes, information may also include insulin/carbohydrate information, and other relevant information. In this manner, a medical device may be customizable by a HCP to include user-specific prescriptive information, some of which may not relate to values or settings in the medical device but may be made available for reference purposes only (e.g., as a text note such as those commonly displayed on a PDA, or the like). A medical device may be lockable by a HCP, who may also set access levels for others such as for a caregiver and/or user. In this manner, a HCP (or other designated individual) may serve as the "Administrator" having the ability to control access at a granular level, establishing access levels on a person-by-person basis.
In addition to, or instead of HCP provided configurations, a caregiver may also enter and/or lock configurations of a medical device. In many embodiments, at least some of the configurations under caregiver control differ at least in part from configurations reserved for HCP control, which would be prescriptive in nature, as described above. Caregiver access may enable a caregiver to enter caregiver information and/or delete and/or modify stored caregiver information.
Caregiver information includes, but is not limited to the ability to set and lock any value or user restriction not previously set and locked by the HCP such as non-prescriptive alarm values, user menu access, and other user privileges such as data transfer (e.g., upload to a PC) and storage options (e.g., read-only or read-write access to various data). For example, a HCP may set and lock values and allowed options (e.g., lock menus).
The caregiver access allowed by the HCP can set and lock that which the HCP did not lock.
Caregiver access may provide the caregiver with the ability to lock and/or unlock user features, such as providing the user with increased access over time as the user begins to understand and appreciate the subtleties and complexities of various features (e.g., setting correct values such as alarm thresholds and reminder time values or accessing menus that show information that might be confusing if not interpreted properly).
Similarly, the user may be able to access that allowed by the caregiver (and HCP), and may be able to set that which is not locked.
The configurations may be set and/or locked by inputting data directly into the medical device using, e.g., a user interface, or may be accomplished indirectly including remotely, e.g., via a computer system connected to a network, where a network represents any uni- or bi- directional communication link suitable for communicating data, such as a wide-area network, local area network, or a global computer network like the World Wide Web ("the Web"). Accordingly, embodiments include a web-based data management system that allows persons to controllably access and/or manipulate and/or share information, depending on a given person's permission level. Each HCP and/or caregiver and/or medical device user may interact with a computing device suitable for accessing the data management system via a network. For example, a personal computer, laptop computer, phone such as a cellular telephone, a personal digital assistant (PDA), etc., may be used. The communication device typically executes communication software, typically a web browser such as INTERNET EXPLORER from Microsoft Corporation of Redmond, Wash., or the like, in order to communicate with the data management system.
(208) that falls in the lower alarm zone (124). This reading causes meter 12 to generate an alarm indicating that the glucose level is in a lower level of high concern. The user responds by eating a modest meal and some time later (e.g. 15 minutes), a reminder prompts the user to test, resulting in a reading of 63 mg/dL (209) that falls in the lower alert zone (116). This reading causes meter 12 to generate an alert indicating that the glucose level is now in a lower level of moderate concern. The user may note that the previous therapy (meal) was appropriate or may eat a small amount (snack) and again some time later (e.g. 25 minutes), a reminder prompts the user to test, resulting in a reading of 99 mg/dL (210) that falls in the ideal zone (110) and confirms the course of therapy was appropriate.
It should be noted that in this example, tests 201, 203, 206 and 208 were initiated by the user based on events known by the user to cause changes in blood glucose, or based on symptoms experienced by the user. More importantly, the user was prompted to perform tests 202, 204, 205, 207, 209 and 210 by a meter constructed according to aspects of the present invention. These prompts or timed reminders assist the user in performing appropriate tests in a timely manner. These tests in turn facilitate the user's important goal of keeping his or her blood glucose level in the ideal zone 110 to maintain the user's short-term and long-term health.
Embodiments also include supervisor-controllable, including person-restrictive (e.g., user-restrictive), medical devices. Configurations of a medical devices may be settable and/or lockable by a supervisor (e.g., a HCP, parent or guardian, caregiver, or the like), e.g., remotely or by direct action (e.g., using a user interface of the device, or the like). For example, certain configurations of a medical device may be settable and/or lockable by a first person (e.g., a HCP) having a first access level (e.g., full access such as full Read/Write permission) and certain configurations that may be settable and/or lockable by a second person (e.g., a caregiver) having a second access level (e.g., limited Read/Write permission). The medical device may be settable and/or lockable by a third person (e.g., a user under the supervision of the first and second persons) having a third access level (e.g., further limited, e.g., Read only -including no rights to modify previously inputted data). Any number of persons may have certain or limited access rights to a medical device. For example, certain embodiments include medical devices having certain configurations settable and/or lockable by a HCP and certain other features settable and/or lockable by a caregiver. A user may be completely restricted from modifying the configurations set by the HCP and/or caregiver.
Configurations may be access controlled with an access code (e.g., password protected, voice authentication, USB token protected, or other manner of authenticating a user) to allow access permissions for a specific individual, medical device, computer, or group of individuals. When permission is set, the type and level of access granted to an individual, computer, or group is granted. For example, various degrees of, e.g., Read and Write and View permissions may be granted to different persons, as described above.
Different codes may provide different rights. For example an HCP code may enable a HCP to enter prescriptive information and/or delete and/or modify stored prescriptive ("Rx") information, where prescriptive information is broadly defined relevant information prescribed by a HCP. Prescriptive information may include patient-specific data and may include but is not limited to, one or a plurality of basal rates, insulin ideal analyte ranges, alert and alarm thresholds, medication type (e.g., insulin type), medication dose including total daily dose (e.g., total daily insulin dosage), drug sensitivity (e.g., insulin sensitivity), when to take a medication, how to take a medication, when to treat a condition, how to treat a condition, when to elevate concerns to a HCP or caregiver, reminder schemes (e.g., setting times of reminders), etc. The above is not an exhaustive list, e.g., for treating diabetes, information may also include insulin/carbohydrate information, and other relevant information. In this manner, a medical device may be customizable by a HCP to include user-specific prescriptive information, some of which may not relate to values or settings in the medical device but may be made available for reference purposes only (e.g., as a text note such as those commonly displayed on a PDA, or the like). A medical device may be lockable by a HCP, who may also set access levels for others such as for a caregiver and/or user. In this manner, a HCP (or other designated individual) may serve as the "Administrator" having the ability to control access at a granular level, establishing access levels on a person-by-person basis.
In addition to, or instead of HCP provided configurations, a caregiver may also enter and/or lock configurations of a medical device. In many embodiments, at least some of the configurations under caregiver control differ at least in part from configurations reserved for HCP control, which would be prescriptive in nature, as described above. Caregiver access may enable a caregiver to enter caregiver information and/or delete and/or modify stored caregiver information.
Caregiver information includes, but is not limited to the ability to set and lock any value or user restriction not previously set and locked by the HCP such as non-prescriptive alarm values, user menu access, and other user privileges such as data transfer (e.g., upload to a PC) and storage options (e.g., read-only or read-write access to various data). For example, a HCP may set and lock values and allowed options (e.g., lock menus).
The caregiver access allowed by the HCP can set and lock that which the HCP did not lock.
Caregiver access may provide the caregiver with the ability to lock and/or unlock user features, such as providing the user with increased access over time as the user begins to understand and appreciate the subtleties and complexities of various features (e.g., setting correct values such as alarm thresholds and reminder time values or accessing menus that show information that might be confusing if not interpreted properly).
Similarly, the user may be able to access that allowed by the caregiver (and HCP), and may be able to set that which is not locked.
The configurations may be set and/or locked by inputting data directly into the medical device using, e.g., a user interface, or may be accomplished indirectly including remotely, e.g., via a computer system connected to a network, where a network represents any uni- or bi- directional communication link suitable for communicating data, such as a wide-area network, local area network, or a global computer network like the World Wide Web ("the Web"). Accordingly, embodiments include a web-based data management system that allows persons to controllably access and/or manipulate and/or share information, depending on a given person's permission level. Each HCP and/or caregiver and/or medical device user may interact with a computing device suitable for accessing the data management system via a network. For example, a personal computer, laptop computer, phone such as a cellular telephone, a personal digital assistant (PDA), etc., may be used. The communication device typically executes communication software, typically a web browser such as INTERNET EXPLORER from Microsoft Corporation of Redmond, Wash., or the like, in order to communicate with the data management system.
Once configurations are set, e.g., by a HCP, caregiver or user, the stored information may be employed by the medical device in the execution of healthcare management, e.g., glucose monitoring. The stored information may be conveyed to a user in audible format and/or visual and/or tactile format. For example, prescriptive information inputted by a HCP may be visually displayed on the display of a medical device, e.g., as an icon (e.g., an "Rx" icon, as a note (similar to displayed PDF notes), or the like), or may be in audible or tactile form.
Fig. 7A shows the hierarchal permission scheme of an embodiment of a medical device 300 having restrictive control, e.g., restrictive caregiver and user control. The most critical settings and portions of the user interface (e.g. the ability to set values and activate menu items) may be set by a HCP. Values that must be prescribed by a HCP
are in the HCP Only portion of the user interface as bounded by the dashed line 310.
Additional values prescribed by the HCP are included in the HCP settings region 320 as bounded by the solid line 330. For example, the HCP may restrict access to various options and menus (e.g., data transfer and storage parameters) and may set and lock various values such as, for example, the lower threshold for high concern and the associated alarm parameters. A caregiver (e.g. a parent) may set additional restrictions by the Caregiver settings region 340 as bounded by the solid line 350. For example, the care giver may set and lock the previously unlocked upper threshold for high concern and the associated alarm parameters and set preferred values for other threshold and the associated alarm parameters without locking those values (i.e., the user may update those values at a later time). Finally, the user of the medical device is allowed access to the User Allowed portion of the user interface as bounded by the solid line 360 along with a portion of the user interface that is always allowed, which is included the User region 370 of the user interface.
Figure 7B shows medical device 300 of Fig 7A, but in this embodiments there is no caregiver and the User region 370 includes of all portions of the user interface that are not restricted by the HCP in the HCP settings region 320.
Fig. 8 shows medical device 300 as connected to a Data Management System (DMS) 400 through connection 410 which may be wired or wireless. The DMS 400 may interface to many medical devices where only one is shown, and each may be of similar or differing types (e.g. analyte meter (such as a blood glucose meter), Continuous analyte monitor (such as a continuous glucose monitor), drug infusion pump (such as an insulin pump).
Fig. 9 shows application software (SW) that runs on the DMS 400 where the DMS Application SW 500 interfaces to the medical device (not shown) via connection 410. SW 500 may be embodied on a computer readable medium. The DMS
Application SW 500 also interfaces to the HCP Application SW 510, the Caregiver Application SW 520, and the User Application SW 530 through SW connections 540, 550 and 560 respectively. Each of the HCP, Caregiver and User Application SW
modules has the same restrictive user controls (e.g. privileges and restrictions) to those that are set directly on the medical device while allowing a more complete user interface, such as a Graphical User Interface (GUI) such as those commonly found on PC computers. Additional features available only on the DMS 400 through the GUI
(e.g. advanced data graphing features) may also be subject to similar restrictive user controls as described for the medical device.
As for additional details pertinent to the present invention, materials and manufacturing techniques may be employed as within the level of those with skill in the relevant art. The same may hold true with respect to method-based aspects of the invention in terms of additional acts commonly or logically employed. Also, it is contemplated that any optional feature of the inventive variations described may be set forth and claimed independently, or in combination with any one or more of the features described herein. Likewise, reference to a singular item, includes the possibility that there are plural of the same items present. More specifically, as used herein and in the appended claims, the singular forms "a," "an," "said," and "the"
include plural referents unless the context clearly dictates otherwise. It is further noted that the claims may be drafted to exclude any optional element. As such, this statement is intended to serve as antecedent basis for use of such exclusive terminology as "solely," "only" and the like in connection with the recitation of claim elements, or use of a "negative" limitation. Unless defined otherwise herein, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The breadth of the present invention is not to be limited by the subject specification, but rather only by the plain meaning of the claim terms employed.
Fig. 7A shows the hierarchal permission scheme of an embodiment of a medical device 300 having restrictive control, e.g., restrictive caregiver and user control. The most critical settings and portions of the user interface (e.g. the ability to set values and activate menu items) may be set by a HCP. Values that must be prescribed by a HCP
are in the HCP Only portion of the user interface as bounded by the dashed line 310.
Additional values prescribed by the HCP are included in the HCP settings region 320 as bounded by the solid line 330. For example, the HCP may restrict access to various options and menus (e.g., data transfer and storage parameters) and may set and lock various values such as, for example, the lower threshold for high concern and the associated alarm parameters. A caregiver (e.g. a parent) may set additional restrictions by the Caregiver settings region 340 as bounded by the solid line 350. For example, the care giver may set and lock the previously unlocked upper threshold for high concern and the associated alarm parameters and set preferred values for other threshold and the associated alarm parameters without locking those values (i.e., the user may update those values at a later time). Finally, the user of the medical device is allowed access to the User Allowed portion of the user interface as bounded by the solid line 360 along with a portion of the user interface that is always allowed, which is included the User region 370 of the user interface.
Figure 7B shows medical device 300 of Fig 7A, but in this embodiments there is no caregiver and the User region 370 includes of all portions of the user interface that are not restricted by the HCP in the HCP settings region 320.
Fig. 8 shows medical device 300 as connected to a Data Management System (DMS) 400 through connection 410 which may be wired or wireless. The DMS 400 may interface to many medical devices where only one is shown, and each may be of similar or differing types (e.g. analyte meter (such as a blood glucose meter), Continuous analyte monitor (such as a continuous glucose monitor), drug infusion pump (such as an insulin pump).
Fig. 9 shows application software (SW) that runs on the DMS 400 where the DMS Application SW 500 interfaces to the medical device (not shown) via connection 410. SW 500 may be embodied on a computer readable medium. The DMS
Application SW 500 also interfaces to the HCP Application SW 510, the Caregiver Application SW 520, and the User Application SW 530 through SW connections 540, 550 and 560 respectively. Each of the HCP, Caregiver and User Application SW
modules has the same restrictive user controls (e.g. privileges and restrictions) to those that are set directly on the medical device while allowing a more complete user interface, such as a Graphical User Interface (GUI) such as those commonly found on PC computers. Additional features available only on the DMS 400 through the GUI
(e.g. advanced data graphing features) may also be subject to similar restrictive user controls as described for the medical device.
As for additional details pertinent to the present invention, materials and manufacturing techniques may be employed as within the level of those with skill in the relevant art. The same may hold true with respect to method-based aspects of the invention in terms of additional acts commonly or logically employed. Also, it is contemplated that any optional feature of the inventive variations described may be set forth and claimed independently, or in combination with any one or more of the features described herein. Likewise, reference to a singular item, includes the possibility that there are plural of the same items present. More specifically, as used herein and in the appended claims, the singular forms "a," "an," "said," and "the"
include plural referents unless the context clearly dictates otherwise. It is further noted that the claims may be drafted to exclude any optional element. As such, this statement is intended to serve as antecedent basis for use of such exclusive terminology as "solely," "only" and the like in connection with the recitation of claim elements, or use of a "negative" limitation. Unless defined otherwise herein, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The breadth of the present invention is not to be limited by the subject specification, but rather only by the plain meaning of the claim terms employed.
Claims (25)
1. A medical device for infusing a drug to a user, the device comprising:
an infusion device for infusing a drug to a patient; and a user interface for conveying infusion information to the user, wherein configurations of the medical device are settable by a supervisor and lockable with the use of an access code.
an infusion device for infusing a drug to a patient; and a user interface for conveying infusion information to the user, wherein configurations of the medical device are settable by a supervisor and lockable with the use of an access code.
2. The medical device of claim 1, comprising a data management system.
3. The medical device of claim 1, wherein the configurations are remotely settable and lockable.
4. The medical device of claim 3, wherein the medical device is connectable to a computer network and the configurations are settable and lockable through the network.
5. The medical device of claim 1, wherein the medical device comprises a plurality of access codes.
6. The medical device of claim 1, wherein the medical device comprises at least two access codes.
7. The medical device of claim 6, wherein the medical device comprises a healthcare professional access code and a caregiver access code.
8. The medical device of claim 7, wherein the medical device further comprises a user access code.
9. The medical device of claim 1, wherein the supervisor is a healthcare professional or a caregiver.
10. The medical device of claim 9, wherein the medical device restricts access to a user.
11. The medical device of claim 1, wherein the supervisor is a healthcare professional.
12. The medical device of claim 11, wherein the configurations comprise a reminder for reminding a user to take an action.
13. The medical device of claim 11, wherein the configurations comprise infusion information.
14. The medical device of claim 13, wherein the infusion information comprises bolus information.
15. The medical device of claim 11, wherein the configurations are prescriptive.
16. The medical device of claim 15, wherein the configurations comprise medication information.
17. The medical device of claim 11, wherein notes conveyed to the user on the medical device may be remotely input by the healthcare professional.
18. The medical device of claim 1, wherein the supervisor is a caregiver.
19. The medical device of claim 1, wherein a user has restricted access to the medical device.
20. The medical device of claim 19, wherein the restricted access comprises the inability to modify supervisor-set configurations.
21. The medical device of claim 1, wherein the infusion device is an insulin infusion device.
22. The medical device of claim 1, wherein the medical device is connected to an analyte monitoring system.
23. A medical system comprising:
a glucose monitoring system;
an insulin pump; and a data management system connectable to the glucose monitoring system, the pump or both the glucose monitoring system and the pump, the data management system having permission hierarchy that enables a plurality of individuals to have different permission rights to enter and modify data in the glucose monitoring system, the pump or both the glucose monitoring system and the pump.
a glucose monitoring system;
an insulin pump; and a data management system connectable to the glucose monitoring system, the pump or both the glucose monitoring system and the pump, the data management system having permission hierarchy that enables a plurality of individuals to have different permission rights to enter and modify data in the glucose monitoring system, the pump or both the glucose monitoring system and the pump.
24. A restrictive control medical system comprising:
an infusion device; and a user interface adapted to convey infusion information to a user, wherein portions of the user interface are assigned an identifier to provide restrictive access to the portions.
an infusion device; and a user interface adapted to convey infusion information to a user, wherein portions of the user interface are assigned an identifier to provide restrictive access to the portions.
25. A medical system for use by a user comprising:
a medical device for infusing an agent and configured to enable at least one person other than the user of the device to set a parameter of the device, which parameter cannot be set or modified by the user.
a medical device for infusing an agent and configured to enable at least one person other than the user of the device to set a parameter of the device, which parameter cannot be set or modified by the user.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/555,207 | 2006-10-31 | ||
US11/555,207 US8579853B2 (en) | 2006-10-31 | 2006-10-31 | Infusion devices and methods |
PCT/US2007/082413 WO2008055037A2 (en) | 2006-10-31 | 2007-10-24 | Infusion devices and methods |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2667952A1 true CA2667952A1 (en) | 2008-05-08 |
Family
ID=39331208
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002667952A Abandoned CA2667952A1 (en) | 2006-10-31 | 2007-10-24 | Infusion devices and methods |
Country Status (10)
Country | Link |
---|---|
US (7) | US8579853B2 (en) |
EP (1) | EP2079500A4 (en) |
JP (2) | JP4908592B2 (en) |
CN (1) | CN101534883A (en) |
AU (1) | AU2007313880A1 (en) |
BR (1) | BRPI0718146A2 (en) |
CA (1) | CA2667952A1 (en) |
MX (1) | MX2009004577A (en) |
RU (1) | RU2009120566A (en) |
WO (1) | WO2008055037A2 (en) |
Families Citing this family (90)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080172026A1 (en) * | 2006-10-17 | 2008-07-17 | Blomquist Michael L | Insulin pump having a suspension bolus |
EP2322798A1 (en) | 2002-10-09 | 2011-05-18 | Abbott Diabetes Care Inc. | Device and method for delivering medical fluids using a shape memory alloy |
US7727181B2 (en) | 2002-10-09 | 2010-06-01 | Abbott Diabetes Care Inc. | Fluid delivery device with autocalibration |
US7993108B2 (en) | 2002-10-09 | 2011-08-09 | Abbott Diabetes Care Inc. | Variable volume, shape memory actuated insulin dispensing pump |
US7182738B2 (en) * | 2003-04-23 | 2007-02-27 | Marctec, Llc | Patient monitoring apparatus and method for orthosis and other devices |
US7679407B2 (en) | 2003-04-28 | 2010-03-16 | Abbott Diabetes Care Inc. | Method and apparatus for providing peak detection circuitry for data communication systems |
US20190357827A1 (en) | 2003-08-01 | 2019-11-28 | Dexcom, Inc. | Analyte sensor |
US7920906B2 (en) | 2005-03-10 | 2011-04-05 | Dexcom, Inc. | System and methods for processing analyte sensor data for sensor calibration |
US9247900B2 (en) | 2004-07-13 | 2016-02-02 | Dexcom, Inc. | Analyte sensor |
US8532730B2 (en) | 2006-10-04 | 2013-09-10 | Dexcom, Inc. | Analyte sensor |
US7946984B2 (en) | 2004-07-13 | 2011-05-24 | Dexcom, Inc. | Transcutaneous analyte sensor |
US8133178B2 (en) | 2006-02-22 | 2012-03-13 | Dexcom, Inc. | Analyte sensor |
WO2006102412A2 (en) | 2005-03-21 | 2006-09-28 | Abbott Diabetes Care, Inc. | Method and system for providing integrated medication infusion and analyte monitoring system |
US7768408B2 (en) | 2005-05-17 | 2010-08-03 | Abbott Diabetes Care Inc. | Method and system for providing data management in data monitoring system |
US7620437B2 (en) | 2005-06-03 | 2009-11-17 | Abbott Diabetes Care Inc. | Method and apparatus for providing rechargeable power in data monitoring and management systems |
US7583190B2 (en) | 2005-10-31 | 2009-09-01 | Abbott Diabetes Care Inc. | Method and apparatus for providing data communication in data monitoring and management systems |
US8344966B2 (en) | 2006-01-31 | 2013-01-01 | Abbott Diabetes Care Inc. | Method and system for providing a fault tolerant display unit in an electronic device |
US8579853B2 (en) | 2006-10-31 | 2013-11-12 | Abbott Diabetes Care Inc. | Infusion devices and methods |
FI20065735A0 (en) * | 2006-11-20 | 2006-11-20 | Salla Koski | Measurement, monitoring and management system and its constituent equipment |
US20080228056A1 (en) | 2007-03-13 | 2008-09-18 | Michael Blomquist | Basal rate testing using frequent blood glucose input |
US7751907B2 (en) | 2007-05-24 | 2010-07-06 | Smiths Medical Asd, Inc. | Expert system for insulin pump therapy |
US8221345B2 (en) | 2007-05-30 | 2012-07-17 | Smiths Medical Asd, Inc. | Insulin pump based expert system |
ES2693097T3 (en) * | 2007-05-30 | 2018-12-07 | Ascensia Diabetes Care Holdings Ag | System and method for managing health data |
EP2232393B1 (en) * | 2007-12-26 | 2019-02-13 | Roche Diabetes Care GmbH | Maintaining glycemic control during exercise |
US20090177147A1 (en) | 2008-01-07 | 2009-07-09 | Michael Blomquist | Insulin pump with insulin therapy coaching |
WO2009105709A1 (en) | 2008-02-21 | 2009-08-27 | Dexcom, Inc. | Systems and methods for processing, transmitting and displaying sensor data |
IL197532A0 (en) | 2008-03-21 | 2009-12-24 | Lifescan Scotland Ltd | Analyte testing method and system |
EP2321755B1 (en) * | 2008-08-11 | 2017-06-21 | Roche Diabetes Care GmbH | Ambulatory medical device comprising an alert controller |
US9326707B2 (en) | 2008-11-10 | 2016-05-03 | Abbott Diabetes Care Inc. | Alarm characterization for analyte monitoring devices and systems |
WO2010066746A1 (en) * | 2008-12-11 | 2010-06-17 | Sanofi-Aventis Deutschland Gmbh | Medical delivery device |
US8560082B2 (en) | 2009-01-30 | 2013-10-15 | Abbott Diabetes Care Inc. | Computerized determination of insulin pump therapy parameters using real time and retrospective data processing |
BRPI1008849B8 (en) * | 2009-02-04 | 2021-06-22 | Sanofi Aventis Deutschland | medical device and method for glycemic control |
US10729357B2 (en) | 2010-04-22 | 2020-08-04 | Leaf Healthcare, Inc. | Systems and methods for generating and/or adjusting a repositioning schedule for a person |
US11278237B2 (en) * | 2010-04-22 | 2022-03-22 | Leaf Healthcare, Inc. | Devices, systems, and methods for preventing, detecting, and treating pressure-induced ischemia, pressure ulcers, and other conditions |
WO2010129375A1 (en) | 2009-04-28 | 2010-11-11 | Abbott Diabetes Care Inc. | Closed loop blood glucose control algorithm analysis |
US8595607B2 (en) | 2009-06-04 | 2013-11-26 | Abbott Diabetes Care Inc. | Method and system for updating a medical device |
EP3936032A1 (en) | 2009-07-23 | 2022-01-12 | Abbott Diabetes Care, Inc. | Real time management of data relating to physiological control of glucose levels |
WO2011014704A2 (en) | 2009-07-30 | 2011-02-03 | Tandem Diabetes Care, Inc. | Infusion pump system with disposable cartridge having pressure venting and pressure feedback |
ES2912584T3 (en) * | 2009-08-31 | 2022-05-26 | Abbott Diabetes Care Inc | A glucose monitoring system and method |
US8882701B2 (en) | 2009-12-04 | 2014-11-11 | Smiths Medical Asd, Inc. | Advanced step therapy delivery for an ambulatory infusion pump and system |
US9041730B2 (en) | 2010-02-12 | 2015-05-26 | Dexcom, Inc. | Receivers for analyzing and displaying sensor data |
US10758162B2 (en) | 2010-04-22 | 2020-09-01 | Leaf Healthcare, Inc. | Systems, devices and methods for analyzing a person status based at least on a detected orientation of the person |
US11051751B2 (en) | 2010-04-22 | 2021-07-06 | Leaf Healthcare, Inc. | Calibrated systems, devices and methods for preventing, detecting, and treating pressure-induced ischemia, pressure ulcers, and other conditions |
US11369309B2 (en) | 2010-04-22 | 2022-06-28 | Leaf Healthcare, Inc. | Systems and methods for managing a position management protocol based on detected inclination angle of a person |
US11272860B2 (en) | 2010-04-22 | 2022-03-15 | Leaf Healthcare, Inc. | Sensor device with a selectively activatable display |
JP5584075B2 (en) * | 2010-09-29 | 2014-09-03 | テルモ株式会社 | Medical pump system and medical pump mounting rack |
DK3575796T3 (en) | 2011-04-15 | 2021-01-18 | Dexcom Inc | ADVANCED ANALYZE SENSOR CALIBRATION AND ERROR DETECTION |
WO2013019852A2 (en) | 2011-08-01 | 2013-02-07 | Tandem Diabetes Care, Inc. | Therapy management system |
US9939385B2 (en) * | 2011-09-09 | 2018-04-10 | Church & Dwight Co., Inc. | Systems, methods, and test kits for analyte variation detection |
EP2574953A1 (en) * | 2011-09-30 | 2013-04-03 | General Electric Company | Method for providing remote health monitoring data and associated system |
WO2013120775A1 (en) | 2012-02-13 | 2013-08-22 | Sanofi-Aventis Deutschland Gmbh | Pen-type injection device and electronic clip-on module therefor |
US9335910B2 (en) | 2012-04-23 | 2016-05-10 | Tandem Diabetes Care, Inc. | System and method for reduction of inadvertent activation of medical device during manipulation |
US9238100B2 (en) | 2012-06-07 | 2016-01-19 | Tandem Diabetes Care, Inc. | Device and method for training users of ambulatory medical devices |
US9715327B2 (en) | 2012-06-07 | 2017-07-25 | Tandem Diabetes Care, Inc. | Preventing inadvertent changes in ambulatory medical devices |
US9736210B2 (en) * | 2012-10-01 | 2017-08-15 | Dexcom, Inc. | Analyte data retriever |
US9119528B2 (en) | 2012-10-30 | 2015-09-01 | Dexcom, Inc. | Systems and methods for providing sensitive and specific alarms |
US9907909B2 (en) * | 2012-12-20 | 2018-03-06 | Animas Corporation | Method and system for a hybrid control-to-target and control-to-range model predictive control of an artificial pancreas |
US10434254B2 (en) * | 2012-12-26 | 2019-10-08 | Roche Diabetes Care, Inc. | Method for configuring an insulin pump with configuring device |
US9585563B2 (en) | 2012-12-31 | 2017-03-07 | Dexcom, Inc. | Remote monitoring of analyte measurements |
KR20140110496A (en) * | 2013-03-08 | 2014-09-17 | 삼성전자주식회사 | Drug infusion pump |
US9636070B2 (en) | 2013-03-14 | 2017-05-02 | DePuy Synthes Products, Inc. | Methods, systems, and devices for monitoring and displaying medical parameters for a patient |
US9486171B2 (en) | 2013-03-15 | 2016-11-08 | Tandem Diabetes Care, Inc. | Predictive calibration |
US9242043B2 (en) | 2013-03-15 | 2016-01-26 | Tandem Diabetes Care, Inc. | Field update of an ambulatory infusion pump system |
WO2014175257A1 (en) * | 2013-04-23 | 2014-10-30 | 第一医科株式会社 | Portable device capable of treating meniere's disease and symptoms similar thereto |
US9821908B2 (en) | 2013-06-07 | 2017-11-21 | Bell Helicopter Textron Inc. | System and method for assisting in rotor speed control |
US9867953B2 (en) | 2013-06-21 | 2018-01-16 | Tandem Diabetes Care, Inc. | System and method for infusion set dislodgement detection |
USD742004S1 (en) * | 2014-02-18 | 2015-10-27 | “HTL-STREFA” Spólka Akcyjna | Skin incision device |
CA157667S (en) * | 2014-03-31 | 2015-04-30 | Htl Strefa Spólka Akcyjna | Lancet device |
EP3145561A1 (en) | 2014-05-20 | 2017-03-29 | Cequr SA | Medicine delivery device with restricted access filling port |
US9669160B2 (en) | 2014-07-30 | 2017-06-06 | Tandem Diabetes Care, Inc. | Temporary suspension for closed-loop medicament therapy |
US11035818B2 (en) * | 2014-08-15 | 2021-06-15 | Roche Diabetes Care, Inc. | Blood glucose meter with low cost user interface having programmed graphic indicators |
US20160263316A1 (en) * | 2015-03-12 | 2016-09-15 | Glucome Ltd. | Methods and systems for communicating with an insulin administering device |
US20160267240A1 (en) * | 2015-03-13 | 2016-09-15 | Polymer Technology Systems, Inc. | Systems and methods for automatic reporting of point-of-care (poc) test results |
EP3113054B1 (en) | 2015-07-01 | 2019-09-04 | Roche Diabetes Care GmbH | A portable device and a method for collecting and processing continuous monitoring data indicative of an analyte in a bodily fluid, a medical system and a computer program product |
EP3397140A4 (en) | 2015-12-28 | 2019-08-21 | Dexcom, Inc. | Systems and methods for remote and host monitoring communications |
US10569016B2 (en) | 2015-12-29 | 2020-02-25 | Tandem Diabetes Care, Inc. | System and method for switching between closed loop and open loop control of an ambulatory infusion pump |
US10541987B2 (en) | 2016-02-26 | 2020-01-21 | Tandem Diabetes Care, Inc. | Web browser-based device communication workflow |
DE102016015370A1 (en) * | 2016-12-22 | 2018-06-28 | Drägerwerk AG & Co. KGaA | Medical device with input unit |
US10182750B1 (en) | 2017-04-27 | 2019-01-22 | Verily Life Sciences Llc | Electrically-isolated and moisture-resistant designs for wearable devices |
EP3634528B1 (en) | 2017-06-07 | 2023-06-07 | Shifamed Holdings, LLC | Intravascular fluid movement devices, systems, and methods of use |
DE202018006861U1 (en) | 2017-10-30 | 2023-11-22 | Dexcom, Inc. | Diabetes management partner interface for wireless communication of analyte data |
CN111556763B (en) | 2017-11-13 | 2023-09-01 | 施菲姆德控股有限责任公司 | Intravascular fluid movement device and system |
JP7410034B2 (en) | 2018-02-01 | 2024-01-09 | シファメド・ホールディングス・エルエルシー | Intravascular blood pump and methods of use and manufacture |
KR102280728B1 (en) * | 2019-03-18 | 2021-07-22 | 주식회사 필로시스 | Device and method to guide injecting medicine |
KR20220012922A (en) * | 2019-05-31 | 2022-02-04 | 셀론 파르마 에스.에이. | Electronically managed administration of pharmaceutical compositions |
WO2021016372A1 (en) | 2019-07-22 | 2021-01-28 | Shifamed Holdings, Llc | Intravascular blood pumps with struts and methods of use and manufacture |
EP4034192A4 (en) | 2019-09-25 | 2023-11-29 | Shifamed Holdings, LLC | Intravascular blood pump systems and methods of use and control thereof |
KR102403085B1 (en) * | 2019-12-17 | 2022-05-30 | 이오플로우(주) | Medical liquid infusion apparatus |
US20220384016A1 (en) * | 2021-05-28 | 2022-12-01 | Cilag Gmbh International | Monitoring a health care professional movement relative to a virtual boundary in an operating room |
CN114711741B (en) * | 2022-06-09 | 2022-09-20 | 中国人民解放军总医院第六医学中心 | A integrated device that is used for health management system of breast cancer postoperative |
Family Cites Families (859)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5338157B1 (en) * | 1992-09-09 | 1999-11-02 | Sims Deltec Inc | Systems and methods for communicating with ambulat |
US2508253A (en) | 1946-09-26 | 1950-05-16 | Dean C Haggardt | Compressor unit |
US2915579A (en) | 1955-12-27 | 1959-12-01 | Ions Exchange & Chemical Corp | Separator for electric battery |
US3510747A (en) | 1964-04-02 | 1970-05-05 | Gen Electric | Two part separable battery charger |
US3374337A (en) | 1964-08-28 | 1968-03-19 | Johnson Service Co | Thermal actuator and control therefor |
BE727801A (en) | 1968-02-02 | 1969-07-01 | ||
US3606592A (en) | 1970-05-20 | 1971-09-20 | Bendix Corp | Fluid pump |
US3750687A (en) | 1972-04-28 | 1973-08-07 | Texaco Inc | Method and system for transporting different types of fluid in a pipeline |
US3843455A (en) | 1972-09-13 | 1974-10-22 | M Bier | Apparatus and technique for preservation of isolated organs through perfusion |
US3994799A (en) | 1973-04-17 | 1976-11-30 | Yao Shang J | Blood and tissue detoxification apparatus |
FR2229331A5 (en) * | 1973-05-09 | 1974-12-06 | Thomson Csf | |
US3930493A (en) | 1974-01-23 | 1976-01-06 | Cordis Corporation | Intravascular liquid velocity sensing method using a polarographic electrode |
US4146029A (en) | 1974-04-23 | 1979-03-27 | Ellinwood Jr Everett H | Self-powered implanted programmable medication system and method |
US3923060A (en) | 1974-04-23 | 1975-12-02 | Jr Everett H Ellinwood | Apparatus and method for implanted self-powered medication dispensing having timing and evaluator means |
US4001604A (en) | 1975-04-25 | 1977-01-04 | The United States Of America As Represented By The Secretary Of The Army | Peak value detector |
US4018547A (en) | 1975-08-28 | 1977-04-19 | Rogen Neil E | Pumping by wire elongation |
US4048551A (en) | 1975-12-05 | 1977-09-13 | Bell Telephone Laboratories, Incorporated | Battery charging circuit |
GB1542826A (en) | 1976-01-21 | 1979-03-28 | Sony Corp | Power supply circuits |
US4193397A (en) | 1977-12-01 | 1980-03-18 | Metal Bellows Corporation | Infusion apparatus and method |
GB1598086A (en) | 1977-12-22 | 1981-09-16 | Medistron Ltd | Reflectometers |
US4172770A (en) | 1978-03-27 | 1979-10-30 | Technicon Instruments Corporation | Flow-through electrochemical system analytical method |
CH642432A5 (en) | 1978-05-11 | 1984-04-13 | Rotovolumetric Ag | DEVICE WITH A CYLINDER, A SLIDING PISTON AND A CAPACITIVE TRANSDUCER. |
US4360019A (en) | 1979-02-28 | 1982-11-23 | Andros Incorporated | Implantable infusion device |
DE2911443C2 (en) * | 1979-03-23 | 1981-03-12 | Bodenseewerk Perkin-Elmer & Co GmbH, 7770 Überlingen | Pressure medium operated pump with variable delivery volume |
US4573994A (en) | 1979-04-27 | 1986-03-04 | The Johns Hopkins University | Refillable medication infusion apparatus |
CS210174B1 (en) | 1979-07-12 | 1982-01-29 | Ivan Emmer | Method of making the electric hygrometric sensor |
US4401122A (en) | 1979-08-02 | 1983-08-30 | Children's Hospital Medical Center | Cutaneous methods of measuring body substances |
US4458686A (en) | 1979-08-02 | 1984-07-10 | Children's Hospital Medical Center | Cutaneous methods of measuring body substances |
US4467811A (en) | 1979-08-02 | 1984-08-28 | Children's Hospital Medical Center | Method of polarographic analysis of lactic acid and lactate |
GB2076162B (en) | 1980-05-16 | 1984-05-31 | Hartridge Leslie Ltd | A flowmeter |
JPS57156736A (en) | 1981-03-23 | 1982-09-28 | Olympus Optical Co | Therapeutic capsule apparatus |
EP0064369B1 (en) | 1981-04-24 | 1986-10-08 | Kabushiki Kaisha Kyoto Daiichi Kagaku | A device for automatically and continuously measuring the constituent parts of blood |
US4474309A (en) | 1981-10-22 | 1984-10-02 | Oximetrix, Inc. | Stepping motor control procedure for achieving variable rate, quasi-continuous fluid infusion |
US4529401A (en) | 1982-01-11 | 1985-07-16 | Cardiac Pacemakers, Inc. | Ambulatory infusion pump having programmable parameters |
US4494950A (en) | 1982-01-19 | 1985-01-22 | The Johns Hopkins University | Plural module medication delivery system |
US4472113A (en) | 1982-01-22 | 1984-09-18 | Rogen Neil E | Pumping by martensitic transformation utilization |
US4447224A (en) | 1982-09-20 | 1984-05-08 | Infusaid Corporation | Variable flow implantable infusion apparatus |
US4486190A (en) | 1982-12-27 | 1984-12-04 | Consolidated Controls Corporation | Precision medication dispensing system and method |
FR2544525A1 (en) | 1983-04-12 | 1984-10-19 | Simatec Sarl | PORTABLE APPARATUS FOR SEIZING AND PROCESSING INFORMATION RELATING TO THE HEALTH OF A PERSON |
IT1170375B (en) * | 1983-04-19 | 1987-06-03 | Giuseppe Bombardieri | Implantable device for measuring body fluid parameters |
US4563249A (en) | 1983-05-10 | 1986-01-07 | Orbisphere Corporation Wilmington, Succursale De Collonge-Bellerive | Electroanalytical method and sensor for hydrogen determination |
US4531235A (en) | 1983-06-20 | 1985-07-23 | Motorola, Inc. | Diversity signal strength indicator and site selection apparatus for using same |
US4655880A (en) | 1983-08-01 | 1987-04-07 | Case Western Reserve University | Apparatus and method for sensing species, substances and substrates using oxidase |
US4685903A (en) | 1984-01-06 | 1987-08-11 | Pacesetter Infusion, Ltd. | External infusion pump apparatus |
US4678408A (en) | 1984-01-06 | 1987-07-07 | Pacesetter Infusion, Ltd. | Solenoid drive apparatus for an external infusion pump |
US4562751A (en) | 1984-01-06 | 1986-01-07 | Nason Clyde K | Solenoid drive apparatus for an external infusion pump |
US4524343A (en) | 1984-01-13 | 1985-06-18 | Raychem Corporation | Self-regulated actuator |
US4574809A (en) * | 1984-06-29 | 1986-03-11 | Electro-Biology, Inc. | Portable non-invasive electromagnetic therapy equipment |
US4570492A (en) | 1984-10-01 | 1986-02-18 | Walsh Myles A | Electrochemical flowmeter |
US5004532A (en) | 1985-06-10 | 1991-04-02 | Orbisphere Corporation | Amperometric cell |
US4755173A (en) | 1986-02-25 | 1988-07-05 | Pacesetter Infusion, Ltd. | Soft cannula subcutaneous injection set |
US5349852A (en) | 1986-03-04 | 1994-09-27 | Deka Products Limited Partnership | Pump controller using acoustic spectral analysis |
JPS6340532A (en) | 1986-04-05 | 1988-02-20 | 日本光電工業株式会社 | Apparatus for monitoring blood component |
US5211626A (en) | 1987-05-01 | 1993-05-18 | Product Innovation Holdings Ltd. | Medical infusion apparatus |
EP0290683A3 (en) * | 1987-05-01 | 1988-12-14 | Diva Medical Systems B.V. | Diabetes management system and apparatus |
JP2586495B2 (en) | 1987-07-02 | 1997-02-26 | 日本電気株式会社 | High frequency detection circuit |
GB2206721A (en) | 1987-07-03 | 1989-01-11 | Philips Electronic Associated | Active matrix display device |
JPS6480775A (en) | 1987-09-24 | 1989-03-27 | Mitsugi Inaba | Shape memory alloy spring-driven diaphragm pump |
DE3785207T2 (en) | 1987-09-26 | 1993-07-15 | Hewlett Packard Gmbh | PUMP DEVICE FOR DISPENSING LIQUID AT HIGH PRESSURE. |
JPH0638381Y2 (en) | 1987-11-18 | 1994-10-05 | 株式会社村田製作所 | connector |
US4811564A (en) | 1988-01-11 | 1989-03-14 | Palmer Mark D | Double action spring actuator |
US4890621A (en) * | 1988-01-19 | 1990-01-02 | Northstar Research Institute, Ltd. | Continuous glucose monitoring and a system utilized therefor |
US5012667A (en) | 1988-03-18 | 1991-05-07 | Great Plains Industries, Inc. | Apparatus and method for calibrating a measuring device |
US4976590A (en) | 1988-06-08 | 1990-12-11 | Baldwin Brian E | Fluid conduit-responsively adjustable pump arrangement and pump/conduit arrangement and method, and fluid conduits therefor |
US4850959A (en) | 1988-08-02 | 1989-07-25 | Bioresearch, Inc. | Bioelectrochemical modulation of biological functions using resonant/non-resonant fields synergistically |
US4984581A (en) | 1988-10-12 | 1991-01-15 | Flexmedics Corporation | Flexible guide having two-way shape memory alloy |
US5517434A (en) | 1989-01-31 | 1996-05-14 | Norand Corporation | Data capture system with communicating and recharging docking apparatus and hand-held data terminal means cooperable therewith |
US5366292A (en) | 1989-02-01 | 1994-11-22 | Leybold Ag | Sensor formed from a deformation heat recoverable material having a predetermined range of temperatures in which recovery occurs and used for measuring a physical characteristic of a system |
US4953552A (en) | 1989-04-21 | 1990-09-04 | Demarzo Arthur P | Blood glucose monitoring system |
US5205819A (en) | 1989-05-11 | 1993-04-27 | Bespak Plc | Pump apparatus for biomedical use |
US5139023A (en) * | 1989-06-02 | 1992-08-18 | Theratech Inc. | Apparatus and method for noninvasive blood glucose monitoring |
US5061914A (en) | 1989-06-27 | 1991-10-29 | Tini Alloy Company | Shape-memory alloy micro-actuator |
US4979509A (en) | 1989-07-19 | 1990-12-25 | Northstar Research Institute, Ltd. | Continuous glucose monitoring and a system utilized therefor |
US5320725A (en) | 1989-08-02 | 1994-06-14 | E. Heller & Company | Electrode and method for the detection of hydrogen peroxide |
US5264104A (en) | 1989-08-02 | 1993-11-23 | Gregg Brian A | Enzyme electrodes |
US5190041A (en) * | 1989-08-11 | 1993-03-02 | Palti Yoram Prof | System for monitoring and controlling blood glucose |
US5101814A (en) | 1989-08-11 | 1992-04-07 | Palti Yoram Prof | System for monitoring and controlling blood glucose |
US5568400A (en) | 1989-09-01 | 1996-10-22 | Stark; Edward W. | Multiplicative signal correction method and apparatus |
US5079920A (en) | 1989-12-11 | 1992-01-14 | Whitehead Charles A | Hydraulic shape memory material stress to hydraulic pressure transducer |
US5051880A (en) | 1989-12-29 | 1991-09-24 | At&T Bell Laboratories | Mixed mode regulation controller for a resonant power converter |
US5036861A (en) | 1990-01-11 | 1991-08-06 | Sembrowich Walter L | Method and apparatus for non-invasively monitoring plasma glucose levels |
US5081421A (en) | 1990-05-01 | 1992-01-14 | At&T Bell Laboratories | In situ monitoring technique and apparatus for chemical/mechanical planarization endpoint detection |
US5078683A (en) * | 1990-05-04 | 1992-01-07 | Block Medical, Inc. | Programmable infusion system |
US5155695A (en) | 1990-06-15 | 1992-10-13 | Timing Solutions Corporation | Time scale computation system including complete and weighted ensemble definition |
EP0491717B1 (en) | 1990-07-11 | 1994-01-05 | Curtis Manufacturing Company, Inc. | Light apparatus for use with a compact computer video screen |
DE59010343D1 (en) | 1990-07-11 | 1996-06-27 | Siemens Ag | Arrangement for the electrochemical determination of the oxygen partial pressure pO2 in a liquid measuring medium and method for operating the arrangement |
US5124661A (en) | 1990-07-23 | 1992-06-23 | I-Stat Corporation | Reusable test unit for simulating electrochemical sensor signals for quality assurance of portable blood analyzer instruments |
US5267026A (en) | 1990-08-31 | 1993-11-30 | Canon Kabushiki Kaisha | Video camera with white balance control having the function of inhibiting auto while balance control under a special light source or of a special object |
KR920006894A (en) | 1990-09-27 | 1992-04-28 | 쓰지 하루오 | Active matrix display |
US5527288A (en) | 1990-12-13 | 1996-06-18 | Elan Medical Technologies Limited | Intradermal drug delivery device and method for intradermal delivery of drugs |
EP0563125A4 (en) | 1990-12-17 | 1997-02-26 | Motorola Inc | Dynamically biased amplifier |
US5324599A (en) | 1991-01-29 | 1994-06-28 | Matsushita Electric Industrial Co., Ltd. | Reversible electrode material |
GB9104097D0 (en) | 1991-02-27 | 1991-04-17 | Univ Hospital London Dev Corp | Computer controlled positive displacement pump for physiological flow stimulation |
US5262305A (en) | 1991-03-04 | 1993-11-16 | E. Heller & Company | Interferant eliminating biosensors |
US5593852A (en) | 1993-12-02 | 1997-01-14 | Heller; Adam | Subcutaneous glucose electrode |
JPH04278450A (en) | 1991-03-04 | 1992-10-05 | Adam Heller | Biosensor and method for analyzing subject |
JP3039583B2 (en) | 1991-05-30 | 2000-05-08 | 株式会社日立製作所 | Valve and semiconductor manufacturing apparatus using the same |
US5211371A (en) | 1991-07-22 | 1993-05-18 | Advanced Control Technologies, Inc. | Linearly actuated valve |
US5207666A (en) | 1991-08-30 | 1993-05-04 | Infusaid, Inc. | Passive shuttle metering device for implantable drug delivery system |
US5291614A (en) | 1991-09-03 | 1994-03-01 | International Business Machines Corporation | Real-time, concurrent, multifunction digital signal processor subsystem for personal computers |
FI89110C (en) | 1991-09-19 | 1993-08-10 | Nokia Mobile Phones Ltd | Power detector |
JP2996559B2 (en) * | 1992-01-29 | 2000-01-11 | 本田技研工業株式会社 | Electric vehicle charging status display system |
NL9200207A (en) | 1992-02-05 | 1993-09-01 | Nedap Nv | IMPLANTABLE BIOMEDICAL SENSOR DEVICE, IN PARTICULAR FOR MEASUREMENT OF THE GLUCOSE CONCENTRATION. |
EP0636009B1 (en) | 1992-04-03 | 2000-11-29 | Micromedical Industries Limited | system for physiological monitoring |
US5223822A (en) | 1992-04-24 | 1993-06-29 | Stonel Corporation | Valve position indicator |
NL9201059A (en) | 1992-06-15 | 1994-01-03 | Bootsman Holding Bv | POSITION DETECTION SYSTEM. |
US5376070A (en) | 1992-09-29 | 1994-12-27 | Minimed Inc. | Data transfer system for an infusion pump |
US5601435A (en) | 1994-11-04 | 1997-02-11 | Intercare | Method and apparatus for interactively monitoring a physiological condition and for interactively providing health related information |
US5899855A (en) | 1992-11-17 | 1999-05-04 | Health Hero Network, Inc. | Modular microprocessor-based health monitoring system |
US5918603A (en) | 1994-05-23 | 1999-07-06 | Health Hero Network, Inc. | Method for treating medical conditions using a microprocessor-based video game |
US5956501A (en) | 1997-01-10 | 1999-09-21 | Health Hero Network, Inc. | Disease simulation system and method |
US20010011224A1 (en) | 1995-06-07 | 2001-08-02 | Stephen James Brown | Modular microprocessor-based health monitoring system |
US5284425A (en) * | 1992-11-18 | 1994-02-08 | The Lee Company | Fluid metering pump |
US5371687A (en) * | 1992-11-20 | 1994-12-06 | Boehringer Mannheim Corporation | Glucose test data acquisition and management system |
US5398681A (en) | 1992-12-10 | 1995-03-21 | Sunshine Medical Instruments, Inc. | Pocket-type instrument for non-invasive measurement of blood glucose concentration |
US5448992A (en) | 1992-12-10 | 1995-09-12 | Sunshine Medical Instruments, Inc. | Method and apparatus for non-invasive phase sensitive measurement of blood glucose concentration |
US5545143A (en) | 1993-01-21 | 1996-08-13 | T. S. I. Medical | Device for subcutaneous medication delivery |
KR100323001B1 (en) | 1993-01-21 | 2002-06-20 | 이데이 노부유끼 | Cathode ray tube driving circuit |
JP2849300B2 (en) | 1993-03-15 | 1999-01-20 | ローム株式会社 | Cordless telephone |
GB9308294D0 (en) | 1993-04-22 | 1993-06-09 | Gilbarco Ltd | Error detection apparatus for an electro-optic display |
US5543678A (en) | 1993-05-11 | 1996-08-06 | Hoiberg; Dane A. | Flat motors |
US5382331A (en) | 1993-07-26 | 1995-01-17 | Nalco Chemical Company | Method and apparatus for inline electrochemical monitoring and automated control of oxidizing or reducing agents in water systems |
US5559528A (en) | 1993-09-21 | 1996-09-24 | Abbott Laboratories | Display having redundant segments |
US6056738A (en) | 1997-01-31 | 2000-05-02 | Transmedica International, Inc. | Interstitial fluid monitoring |
US5428307A (en) | 1993-10-20 | 1995-06-27 | Silicon Systems, Inc. | Closed-loop peak detector topology |
CA2132277C (en) | 1993-10-22 | 2005-05-10 | Giorgio Cirelli | Injection device |
DE69322968T2 (en) | 1993-10-22 | 1999-07-08 | Siemens Elema Ab | Method and device for continuously monitoring an anolyte level |
US5406301A (en) | 1993-10-27 | 1995-04-11 | Abbott Laboratories | High reliability display |
US5445611A (en) | 1993-12-08 | 1995-08-29 | Non-Invasive Monitoring Company (Nimco) | Enhancement of transdermal delivery with ultrasound and chemical enhancers |
US5458140A (en) * | 1993-11-15 | 1995-10-17 | Non-Invasive Monitoring Company (Nimco) | Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers |
US20020169394A1 (en) | 1993-11-15 | 2002-11-14 | Eppstein Jonathan A. | Integrated tissue poration, fluid harvesting and analysis device, and method therefor |
US5885211A (en) * | 1993-11-15 | 1999-03-23 | Spectrix, Inc. | Microporation of human skin for monitoring the concentration of an analyte |
US5814599A (en) * | 1995-08-04 | 1998-09-29 | Massachusetts Insitiute Of Technology | Transdermal delivery of encapsulated drugs |
US5997501A (en) | 1993-11-18 | 1999-12-07 | Elan Corporation, Plc | Intradermal drug delivery device |
US5791344A (en) | 1993-11-19 | 1998-08-11 | Alfred E. Mann Foundation For Scientific Research | Patient monitoring system |
US5497772A (en) | 1993-11-19 | 1996-03-12 | Alfred E. Mann Foundation For Scientific Research | Glucose monitoring system |
GB9325189D0 (en) | 1993-12-08 | 1994-02-09 | Unilever Plc | Methods and apparatus for electrochemical measurements |
DE4401400A1 (en) | 1994-01-19 | 1995-07-20 | Ernst Prof Dr Pfeiffer | Method and arrangement for continuously monitoring the concentration of a metabolite |
US5391250A (en) | 1994-03-15 | 1995-02-21 | Minimed Inc. | Method of fabricating thin film sensors |
US5390671A (en) | 1994-03-15 | 1995-02-21 | Minimed Inc. | Transcutaneous sensor insertion set |
US6408402B1 (en) | 1994-03-22 | 2002-06-18 | Hyperchip Inc. | Efficient direct replacement cell fault tolerant architecture |
AU700629B2 (en) | 1994-03-22 | 1999-01-07 | Hyperchip Inc. | Efficient direct cell replacement fault tolerant architecture supporting completely integrated systems with means for direct communication with system operator |
US5505713A (en) | 1994-04-01 | 1996-04-09 | Minimed Inc. | Indwelling catheter with stable enzyme coating |
FR2718492B1 (en) | 1994-04-11 | 1996-04-26 | Georges Pataillot | Motor device for pistons and valves of a pump or compressor comprising a shape memory member. |
DE4415896A1 (en) | 1994-05-05 | 1995-11-09 | Boehringer Mannheim Gmbh | Analysis system for monitoring the concentration of an analyte in the blood of a patient |
US5771890A (en) * | 1994-06-24 | 1998-06-30 | Cygnus, Inc. | Device and method for sampling of substances using alternating polarity |
US5494562A (en) * | 1994-06-27 | 1996-02-27 | Ciba Corning Diagnostics Corp. | Electrochemical sensors |
US5622413A (en) | 1994-08-17 | 1997-04-22 | Daewoo Electronics Co., Ltd. | Valve utilizing shape memory alloys and an anti-lock brake system with the valve |
CA2159052C (en) | 1994-10-28 | 2007-03-06 | Rainer Alex | Injection device |
KR100199844B1 (en) | 1994-10-31 | 1999-06-15 | 배길훈 | Fluid pump |
JPH08210248A (en) | 1994-10-31 | 1996-08-20 | Harry Ono | Composite type piston-pump |
IE72524B1 (en) | 1994-11-04 | 1997-04-23 | Elan Med Tech | Analyte-controlled liquid delivery device and analyte monitor |
US5573506A (en) | 1994-11-25 | 1996-11-12 | Block Medical, Inc. | Remotely programmable infusion system |
US6749586B2 (en) | 1994-11-25 | 2004-06-15 | I-Flow Corporation | Remotely programmable infusion system |
US6425829B1 (en) | 1994-12-06 | 2002-07-30 | Nitinol Technologies, Inc. | Threaded load transferring attachment |
US5685844A (en) | 1995-01-06 | 1997-11-11 | Abbott Laboratories | Medicinal fluid pump having multiple stored protocols |
EP0724859B1 (en) | 1995-02-04 | 1997-11-12 | Baumann & Haldi S.A. | Personal device for measurement, processing and transmission of substantially physiological data |
US5568806A (en) | 1995-02-16 | 1996-10-29 | Minimed Inc. | Transcutaneous sensor insertion set |
US5586553A (en) | 1995-02-16 | 1996-12-24 | Minimed Inc. | Transcutaneous sensor insertion set |
US5788833A (en) | 1995-03-27 | 1998-08-04 | California Institute Of Technology | Sensors for detecting analytes in fluids |
US5786439A (en) | 1996-10-24 | 1998-07-28 | Minimed Inc. | Hydrophilic, swellable coatings for biosensors |
US5575770A (en) | 1995-04-05 | 1996-11-19 | Therex Corporation | Implantable drug infusion system with safe bolus capability |
US5695949A (en) | 1995-04-07 | 1997-12-09 | Lxn Corp. | Combined assay for current glucose level and intermediate or long-term glycemic control |
US6224572B1 (en) | 1995-05-04 | 2001-05-01 | Sarcos L.C. | Piston-actuated attachable topical fluid delivery system |
US5620579A (en) | 1995-05-05 | 1997-04-15 | Bayer Corporation | Apparatus for reduction of bias in amperometric sensors |
US5873026A (en) | 1995-07-07 | 1999-02-16 | Reames; James B. | Battery powered voice transmitter and receiver tuned to an RF frequency by the receiver |
US6002961A (en) | 1995-07-25 | 1999-12-14 | Massachusetts Institute Of Technology | Transdermal protein delivery using low-frequency sonophoresis |
US5947921A (en) | 1995-12-18 | 1999-09-07 | Massachusetts Institute Of Technology | Chemical and physical enhancers and ultrasound for transdermal drug delivery |
US6041253A (en) * | 1995-12-18 | 2000-03-21 | Massachusetts Institute Of Technology | Effect of electric field and ultrasound for transdermal drug delivery |
US6082289A (en) | 1995-08-24 | 2000-07-04 | Speedline Technologies, Inc. | Liquid dispensing system with controllably movable cartridge |
IE77523B1 (en) | 1995-09-11 | 1997-12-17 | Elan Med Tech | Medicament delivery device |
US5703928A (en) | 1995-09-26 | 1997-12-30 | Industrial Technology, Inc. | Probe for sampling differential electromagnetic fields |
US5665222A (en) | 1995-10-11 | 1997-09-09 | E. Heller & Company | Soybean peroxidase electrochemical sensor |
US5972199A (en) | 1995-10-11 | 1999-10-26 | E. Heller & Company | Electrochemical analyte sensors using thermostable peroxidase |
US6283951B1 (en) | 1996-10-11 | 2001-09-04 | Transvascular, Inc. | Systems and methods for delivering drugs to selected locations within the body |
US5741211A (en) | 1995-10-26 | 1998-04-21 | Medtronic, Inc. | System and method for continuous monitoring of diabetes-related blood constituents |
DE19543020A1 (en) | 1995-11-18 | 1997-05-22 | Boehringer Mannheim Gmbh | Method and device for determining analytical data on the interior of a scattering matrix |
US5856631A (en) * | 1995-11-20 | 1999-01-05 | Nitinol Technologies, Inc. | Gun barrel |
US5711861A (en) | 1995-11-22 | 1998-01-27 | Ward; W. Kenneth | Device for monitoring changes in analyte concentration |
ZA9610374B (en) * | 1995-12-11 | 1997-06-23 | Elan Med Tech | Cartridge-based drug delivery device |
EP0868144B1 (en) * | 1995-12-19 | 2005-01-26 | Abbott Laboratories | Device for the detection of analyte and administration of a therapeutic substance |
JP3316820B2 (en) | 1995-12-28 | 2002-08-19 | シィグナス インコーポレィティド | Apparatus and method for continuous monitoring of a physiological analyte of a subject |
US5708247A (en) * | 1996-02-14 | 1998-01-13 | Selfcare, Inc. | Disposable glucose test strips, and methods and compositions for making same |
US5661643A (en) | 1996-02-20 | 1997-08-26 | Eaton Corporation | Universal power module |
US20010044588A1 (en) | 1996-02-22 | 2001-11-22 | Mault James R. | Monitoring system |
US5948512A (en) | 1996-02-22 | 1999-09-07 | Seiko Epson Corporation | Ink jet recording ink and recording method |
US6137195A (en) | 1996-03-28 | 2000-10-24 | Anorad Corporation | Rotary-linear actuator |
DE19621365C2 (en) | 1996-05-29 | 1999-12-02 | Krohne Ag Basel | Mass flow meter |
FI102580B (en) | 1996-06-17 | 1998-12-31 | Nokia Mobile Phones Ltd | Procedure for eliminating interference caused by a mobile station |
US7218017B1 (en) | 1996-06-24 | 2007-05-15 | Anorad Corporation | System and method to control a rotary-linear actuator |
US5707502A (en) * | 1996-07-12 | 1998-01-13 | Chiron Diagnostics Corporation | Sensors for measuring analyte concentrations and methods of making same |
AU3892297A (en) | 1996-07-26 | 1998-02-20 | Ikonos Corporation | Sensor for detecting heparin and other analytes |
US6067017A (en) | 1996-08-12 | 2000-05-23 | Harris Corporation | Emergency location system and method |
US5738220A (en) | 1996-09-30 | 1998-04-14 | Pacesetter, Inc. | Distal tip protector cap |
US5759510A (en) | 1996-10-03 | 1998-06-02 | Carus Chemical Company | Lithiated manganese oxide |
EP0878707A4 (en) | 1996-10-22 | 2000-06-28 | Riken Kk | Heating-type sensor |
US6173160B1 (en) | 1996-11-18 | 2001-01-09 | Nokia Mobile Phones Limited | Mobile station having drift-free pulsed power detection method and apparatus |
US5875417A (en) | 1996-11-18 | 1999-02-23 | Isi Norgren Inc. | Clamp arm position sensing apparatus |
US6063039A (en) | 1996-12-06 | 2000-05-16 | Abbott Laboratories | Method and apparatus for obtaining blood for diagnostic tests |
US6027459A (en) | 1996-12-06 | 2000-02-22 | Abbott Laboratories | Method and apparatus for obtaining blood for diagnostic tests |
US8734339B2 (en) * | 1996-12-16 | 2014-05-27 | Ip Holdings, Inc. | Electronic skin patch for real time monitoring of cardiac activity and personal health management |
US6032155A (en) * | 1997-04-14 | 2000-02-29 | De La Huerga; Carlos | System and apparatus for administering prescribed medication to a patient |
CA2228095C (en) | 1997-01-28 | 2002-01-08 | Canon Kabushiki Kaisha | Electrode structural body, rechargeable battery provided with said electrode structural body, and process for the production of said electrode structural body and said rechargeable battery |
US5851197A (en) | 1997-02-05 | 1998-12-22 | Minimed Inc. | Injector for a subcutaneous infusion set |
US6093172A (en) | 1997-02-05 | 2000-07-25 | Minimed Inc. | Injector for a subcutaneous insertion set |
US6607509B2 (en) * | 1997-12-31 | 2003-08-19 | Medtronic Minimed, Inc. | Insertion device for an insertion set and method of using the same |
DE69809391T2 (en) | 1997-02-06 | 2003-07-10 | Therasense Inc | SMALL VOLUME SENSOR FOR IN-VITRO DETERMINATION |
US5913833A (en) | 1997-02-07 | 1999-06-22 | Abbott Laboratories | Method and apparatus for obtaining biological fluids |
AU6667698A (en) | 1997-02-26 | 1998-09-18 | Alfred E. Mann Foundation For Scientific Research | Battery-powered patient implantable device |
US6208894B1 (en) | 1997-02-26 | 2001-03-27 | Alfred E. Mann Foundation For Scientific Research And Advanced Bionics | System of implantable devices for monitoring and/or affecting body parameters |
US6164284A (en) | 1997-02-26 | 2000-12-26 | Schulman; Joseph H. | System of implantable devices for monitoring and/or affecting body parameters |
US7114502B2 (en) | 1997-02-26 | 2006-10-03 | Alfred E. Mann Foundation For Scientific Research | Battery-powered patient implantable device |
US6695885B2 (en) | 1997-02-26 | 2004-02-24 | Alfred E. Mann Foundation For Scientific Research | Method and apparatus for coupling an implantable stimulator/sensor to a prosthetic device |
US6558321B1 (en) * | 1997-03-04 | 2003-05-06 | Dexcom, Inc. | Systems and methods for remote monitoring and modulation of medical devices |
US20050033132A1 (en) * | 1997-03-04 | 2005-02-10 | Shults Mark C. | Analyte measuring device |
US7192450B2 (en) | 2003-05-21 | 2007-03-20 | Dexcom, Inc. | Porous membranes for use with implantable devices |
US7899511B2 (en) | 2004-07-13 | 2011-03-01 | Dexcom, Inc. | Low oxygen in vivo analyte sensor |
US6741877B1 (en) | 1997-03-04 | 2004-05-25 | Dexcom, Inc. | Device and method for determining analyte levels |
US6001067A (en) | 1997-03-04 | 1999-12-14 | Shults; Mark C. | Device and method for determining analyte levels |
US6862465B2 (en) | 1997-03-04 | 2005-03-01 | Dexcom, Inc. | Device and method for determining analyte levels |
US7657297B2 (en) | 2004-05-03 | 2010-02-02 | Dexcom, Inc. | Implantable analyte sensor |
GB9704737D0 (en) | 1997-03-07 | 1997-04-23 | Optel Instr Limited | Biological measurement system |
US5812102A (en) | 1997-03-12 | 1998-09-22 | Union Switch & Signal Inc. | Vital monitoring system for seven-segment display used in railroad applications |
GB9705436D0 (en) | 1997-03-15 | 1997-04-30 | Sharp Kk | Fault tolerant circuit arrangements |
US6027496A (en) | 1997-03-25 | 2000-02-22 | Abbott Laboratories | Removal of stratum corneum by means of light |
US6596016B1 (en) | 1997-03-27 | 2003-07-22 | The Board Of Trustees Of The Leland Stanford Junior University | Phototherapy of jaundiced newborns using garments containing semiconductor light-emitting devices |
KR100224998B1 (en) | 1997-04-09 | 1999-10-15 | 구자홍 | Apparatus and method for remote control user interface of pc system |
US6186982B1 (en) * | 1998-05-05 | 2001-02-13 | Elan Corporation, Plc | Subcutaneous drug delivery device with improved filling system |
US6558351B1 (en) | 1999-06-03 | 2003-05-06 | Medtronic Minimed, Inc. | Closed loop system for controlling insulin infusion |
US5954643A (en) | 1997-06-09 | 1999-09-21 | Minimid Inc. | Insertion set for a transcutaneous sensor |
US7267665B2 (en) | 1999-06-03 | 2007-09-11 | Medtronic Minimed, Inc. | Closed loop system for controlling insulin infusion |
US6278425B1 (en) | 1997-06-10 | 2001-08-21 | Deluca Michael | Single array edge intersecting beam display panel |
US6222514B1 (en) | 1997-06-10 | 2001-04-24 | Deluca Michael J. | Fault tolerant intersecting beam display panel |
US5968011A (en) | 1997-06-20 | 1999-10-19 | Maersk Medical A/S | Subcutaneous injection set |
US5790297A (en) | 1997-06-26 | 1998-08-04 | Xerox Corporation | Optical row displacement for a fault tolerant projective display |
US5774254A (en) | 1997-06-26 | 1998-06-30 | Xerox Corporation | Fault tolerant light modulator display system |
US5815303A (en) | 1997-06-26 | 1998-09-29 | Xerox Corporation | Fault tolerant projective display having redundant light modulators |
US6319466B1 (en) | 1997-07-16 | 2001-11-20 | Charm Sciences, Inc. | Test device for detecting the presence of a residue analyte in a sample |
US6066243A (en) | 1997-07-22 | 2000-05-23 | Diametrics Medical, Inc. | Portable immediate response medical analyzer having multiple testing modules |
GB2328279B (en) | 1997-08-12 | 2001-10-10 | Abbott Lab | Optical glucose detector |
US6232950B1 (en) | 1997-08-28 | 2001-05-15 | E Ink Corporation | Rear electrode structures for displays |
US6731976B2 (en) | 1997-09-03 | 2004-05-04 | Medtronic, Inc. | Device and method to measure and communicate body parameters |
US6764581B1 (en) | 1997-09-05 | 2004-07-20 | Abbott Laboratories | Electrode with thin working layer |
US6129823A (en) | 1997-09-05 | 2000-10-10 | Abbott Laboratories | Low volume electrochemical sensor |
FR2768215B1 (en) | 1997-09-10 | 1999-11-19 | Agence Spatiale Europeenne | SYSTEM FOR LUBRICATING A MECHANISM, IN PARTICULAR A TURNING BEARING IN A SPACE MACHINE |
US6259937B1 (en) | 1997-09-12 | 2001-07-10 | Alfred E. Mann Foundation | Implantable substrate sensor |
US5994878A (en) | 1997-09-30 | 1999-11-30 | Chartec Laboratories A/S | Method and apparatus for charging a rechargeable battery |
AU741646B2 (en) * | 1997-09-30 | 2001-12-06 | L. Vad Technology, Inc. | Cardiovascular support control system |
US7359624B2 (en) | 1997-10-06 | 2008-04-15 | Silicon Image, Inc. | Portable DVD player |
US6088608A (en) | 1997-10-20 | 2000-07-11 | Alfred E. Mann Foundation | Electrochemical sensor and integrity tests therefor |
US6119028A (en) | 1997-10-20 | 2000-09-12 | Alfred E. Mann Foundation | Implantable enzyme-based monitoring systems having improved longevity due to improved exterior surfaces |
FI107080B (en) | 1997-10-27 | 2001-05-31 | Nokia Mobile Phones Ltd | measuring device |
US6144922A (en) | 1997-10-31 | 2000-11-07 | Mercury Diagnostics, Incorporated | Analyte concentration information collection and communication system |
US6117643A (en) * | 1997-11-25 | 2000-09-12 | Ut Battelle, Llc | Bioluminescent bioreporter integrated circuit |
US6482176B1 (en) | 1997-11-27 | 2002-11-19 | Disetronic Licensing Ag | Method and device for controlling the introduction depth of an injection needle |
US6155992A (en) | 1997-12-02 | 2000-12-05 | Abbott Laboratories | Method and apparatus for obtaining interstitial fluid for diagnostic tests |
US6579690B1 (en) | 1997-12-05 | 2003-06-17 | Therasense, Inc. | Blood analyte monitoring through subcutaneous measurement |
US6011486A (en) | 1997-12-16 | 2000-01-04 | Intel Corporation | Electronic paging device including a computer connection port |
US6073031A (en) | 1997-12-24 | 2000-06-06 | Nortel Networks Corporation | Desktop docking station for use with a wireless telephone handset |
CA2484271C (en) | 1997-12-31 | 2007-04-24 | Medtronic Minimed, Inc. | Insertion device for an insertion set and method of using the same |
EP2201969B1 (en) | 1997-12-31 | 2011-03-30 | Medtronic MiniMed, Inc. | Insertion device for an insertion set |
WO1999037921A1 (en) | 1998-01-26 | 1999-07-29 | Massachusetts Institute Of Technology | Contractile actuated bellows pump |
DE69928229T2 (en) | 1998-02-17 | 2006-08-03 | Abbott Laboratories, Abbott Park | DEVICE FOR REMOVING AND ANALYZING INTERSTITUTIONAL LIQUID |
US6134461A (en) | 1998-03-04 | 2000-10-17 | E. Heller & Company | Electrochemical analyte |
US6103033A (en) | 1998-03-04 | 2000-08-15 | Therasense, Inc. | Process for producing an electrochemical biosensor |
US6530915B1 (en) * | 1998-03-06 | 2003-03-11 | Spectrx, Inc. | Photothermal structure for biomedical applications, and method therefor |
WO1999044507A1 (en) | 1998-03-06 | 1999-09-10 | Spectrx, Inc. | Integrated tissue poration, fluid harvesting and analysis device, and method therefor |
US6587705B1 (en) | 1998-03-13 | 2003-07-01 | Lynn Kim | Biosensor, iontophoretic sampling system, and methods of use thereof |
US6086575A (en) | 1998-03-20 | 2000-07-11 | Maersk Medical A/S | Subcutaneous infusion device |
GB9805896D0 (en) | 1998-03-20 | 1998-05-13 | Eglise David | Remote analysis system |
US6091975A (en) | 1998-04-01 | 2000-07-18 | Alza Corporation | Minimally invasive detecting device |
US6728560B2 (en) * | 1998-04-06 | 2004-04-27 | The General Hospital Corporation | Non-invasive tissue glucose level monitoring |
JPH11296598A (en) | 1998-04-07 | 1999-10-29 | Seizaburo Arita | System and method for predicting blood-sugar level and record medium where same method is recorded |
US5919167A (en) | 1998-04-08 | 1999-07-06 | Ferring Pharmaceuticals | Disposable micropump |
US7647237B2 (en) * | 1998-04-29 | 2010-01-12 | Minimed, Inc. | Communication station and software for interfacing with an infusion pump, analyte monitor, analyte meter, or the like |
US8974386B2 (en) * | 1998-04-30 | 2015-03-10 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
US6175752B1 (en) | 1998-04-30 | 2001-01-16 | Therasense, Inc. | Analyte monitoring device and methods of use |
US6949816B2 (en) | 2003-04-21 | 2005-09-27 | Motorola, Inc. | Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same |
GB2337122B (en) | 1998-05-08 | 2002-11-13 | Medisense Inc | Test strip |
EP1077634B1 (en) * | 1998-05-13 | 2003-07-30 | Cygnus, Inc. | Monitoring of physiological analytes |
ATE246356T1 (en) | 1998-05-13 | 2003-08-15 | Cygnus Therapeutic Systems | DEVICE FOR PREDICTING PHYSIOLOGICAL MEASUREMENTS |
WO1999058050A1 (en) | 1998-05-13 | 1999-11-18 | Cygnus, Inc. | Signal processing for measurement of physiological analytes |
WO1999058190A1 (en) * | 1998-05-13 | 1999-11-18 | Cygnus, Inc. | Collection assemblies for transdermal sampling system |
US6569157B1 (en) | 1998-05-18 | 2003-05-27 | Abbott Laboratories | Removal of stratum corneum by means of light |
US6526298B1 (en) | 1998-05-18 | 2003-02-25 | Abbott Laboratories | Method for the non-invasive determination of analytes in a selected volume of tissue |
US7043287B1 (en) | 1998-05-18 | 2006-05-09 | Abbott Laboratories | Method for modulating light penetration depth in tissue and diagnostic applications using same |
WO1999060391A1 (en) | 1998-05-20 | 1999-11-25 | Arkray, Inc. | Method and apparatus for electrochemical measurement using statistical technique |
US6132371A (en) | 1998-05-20 | 2000-10-17 | Hewlett-Packard Company | Leadless monitoring of physiological conditions |
US5951582A (en) | 1998-05-22 | 1999-09-14 | Specialized Health Products, Inc. | Lancet apparatus and methods |
US6147342A (en) | 1998-06-02 | 2000-11-14 | Caterpillar Inc. | Encoding system for determining the position of a cylinder rod along a path of movement |
US6026320A (en) * | 1998-06-08 | 2000-02-15 | Cardiac Pacemakers, Inc. | Heart rate variability as an indicator of exercise capacity |
US6301499B1 (en) * | 1998-06-08 | 2001-10-09 | Cardiac Pacemakers, Inc. | Heart rate variability as an indicator of exercise capacity |
US6077660A (en) | 1998-06-10 | 2000-06-20 | Abbott Laboratories | Diagnostic assay requiring a small sample of biological fluid |
US6312888B1 (en) | 1998-06-10 | 2001-11-06 | Abbott Laboratories | Diagnostic assay for a sample of biological fluid |
US6736797B1 (en) | 1998-06-19 | 2004-05-18 | Unomedical A/S | Subcutaneous infusion set |
US6922576B2 (en) | 1998-06-19 | 2005-07-26 | Becton, Dickinson And Company | Micro optical sensor device |
US6157442A (en) | 1998-06-19 | 2000-12-05 | Microsense International Llc | Micro optical fiber sensor device |
IL140493A0 (en) | 1998-06-24 | 2002-02-10 | Transderm Diagnostics Inc | Non-invasive transdermal detection of analytes |
US6280587B1 (en) | 1998-07-02 | 2001-08-28 | Nec Corporation | Enzyme electrode and a biosensor and a measuring apparatus therewith |
US7384396B2 (en) | 1998-07-21 | 2008-06-10 | Spectrx Inc. | System and method for continuous analyte monitoring |
US7077328B2 (en) | 1998-07-31 | 2006-07-18 | Abbott Laboratories | Analyte test instrument system including data management system |
KR100301657B1 (en) | 1998-08-14 | 2001-10-27 | 최수봉 | Control method of insulin syringe with pseudo mode |
US6554798B1 (en) | 1998-08-18 | 2003-04-29 | Medtronic Minimed, Inc. | External infusion device with remote programming, bolus estimator and/or vibration alarm capabilities |
US5993423A (en) | 1998-08-18 | 1999-11-30 | Choi; Soo Bong | Portable automatic syringe device and injection needle unit thereof |
US6248067B1 (en) | 1999-02-05 | 2001-06-19 | Minimed Inc. | Analyte sensor and holter-type monitor system and method of using the same |
US6558320B1 (en) | 2000-01-20 | 2003-05-06 | Medtronic Minimed, Inc. | Handheld personal data assistant (PDA) with a medical device and method of using the same |
US6535753B1 (en) | 1998-08-20 | 2003-03-18 | Microsense International, Llc | Micro-invasive method for painless detection of analytes in extra-cellular space |
US6464848B1 (en) | 1998-09-03 | 2002-10-15 | Nec Corporation | Reference electrode, a biosensor and a measuring apparatus therewith |
DE19840952C1 (en) | 1998-09-08 | 2000-03-23 | Roche Diagnostics Gmbh | LC display with failure control |
US6918874B1 (en) | 1998-09-10 | 2005-07-19 | Spectrx, Inc. | Attribute compensation for analyte detection and/or continuous monitoring |
DE69908602T2 (en) | 1998-09-30 | 2004-06-03 | Cygnus, Inc., Redwood City | METHOD AND DEVICE FOR PREDICTING PHYSIOLOGICAL MEASUREMENTS |
US6735532B2 (en) * | 1998-09-30 | 2004-05-11 | L. Vad Technology, Inc. | Cardiovascular support control system |
US6511412B1 (en) * | 1998-09-30 | 2003-01-28 | L. Vad Technology, Inc. | Cardivascular support control system |
US6180416B1 (en) * | 1998-09-30 | 2001-01-30 | Cygnus, Inc. | Method and device for predicting physiological values |
US6201980B1 (en) | 1998-10-05 | 2001-03-13 | The Regents Of The University Of California | Implantable medical sensor system |
WO2000019887A1 (en) | 1998-10-08 | 2000-04-13 | Minimed Inc. | Telemetered characteristic monitor system |
US6591125B1 (en) | 2000-06-27 | 2003-07-08 | Therasense, Inc. | Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator |
US6338790B1 (en) * | 1998-10-08 | 2002-01-15 | Therasense, Inc. | Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator |
US6242961B1 (en) | 1998-10-08 | 2001-06-05 | Altima Communication, Inc. | Methods and circuits for restoration of a drooped DC signal |
US6162202A (en) | 1998-10-26 | 2000-12-19 | Sicurelli; Robert | Flexible syringe needle |
US7193521B2 (en) | 1998-10-29 | 2007-03-20 | Medtronic Minimed, Inc. | Method and apparatus for detecting errors, fluid pressure, and occlusions in an ambulatory infusion pump |
US6602469B1 (en) | 1998-11-09 | 2003-08-05 | Lifestream Technologies, Inc. | Health monitoring and diagnostic device and network-based health assessment and medical records maintenance system |
US6081104A (en) | 1998-11-20 | 2000-06-27 | Applied Power Corporation | Method and apparatus for providing energy to a lighting system |
US6615061B1 (en) | 1998-11-23 | 2003-09-02 | Abbott Laboratories | Optical sensor having a selectable sampling distance for determination of analytes |
US6377894B1 (en) | 1998-11-30 | 2002-04-23 | Abbott Laboratories | Analyte test instrument having improved calibration and communication processes |
US6288653B1 (en) | 1998-12-22 | 2001-09-11 | Yun Ning Shih | Curved surface signal pick-up device |
US6615074B2 (en) | 1998-12-22 | 2003-09-02 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Apparatus for energizing a remote station and related method |
US6067463A (en) | 1999-01-05 | 2000-05-23 | Abbott Laboratories | Method and apparatus for non-invasively measuring the amount of glucose in blood |
US6203288B1 (en) * | 1999-01-05 | 2001-03-20 | Air Products And Chemicals, Inc. | Reciprocating pumps with linear motor driver |
US7436511B2 (en) * | 1999-01-22 | 2008-10-14 | Sensys Medical, Inc. | Analyte filter method and apparatus |
US6565738B1 (en) | 1999-01-28 | 2003-05-20 | Abbott Laboratories | Diagnostic test for the measurement of analyte in abiological fluid |
US6144303A (en) | 1999-02-01 | 2000-11-07 | Exi Wireless Systems, Inc. | Tag and system for patient safety monitoring |
EP1135052A1 (en) | 1999-02-12 | 2001-09-26 | Cygnus, Inc. | Devices and methods for frequent measurement of an analyte present in a biological system |
US6375638B2 (en) | 1999-02-12 | 2002-04-23 | Medtronic Minimed, Inc. | Incremental motion pump mechanisms powered by shape memory alloy wire or the like |
US6360888B1 (en) | 1999-02-25 | 2002-03-26 | Minimed Inc. | Glucose sensor package system |
JP4801839B2 (en) | 1999-02-25 | 2011-10-26 | メドトロニック ミニメド インコーポレイテッド | Test plug and cable for glucose monitor |
US7208119B1 (en) | 2000-03-01 | 2007-04-24 | Roche Diagnostics Operations, Inc. | Hospital meter system |
US6633095B1 (en) | 1999-03-01 | 2003-10-14 | Charles B. Swope | Motion device using shape memory material and method therefor |
US7299080B2 (en) | 1999-10-08 | 2007-11-20 | Sensys Medical, Inc. | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy |
US6192891B1 (en) * | 1999-04-26 | 2001-02-27 | Becton Dickinson And Company | Integrated system including medication delivery pen, blood monitoring device, and lancer |
US6669663B1 (en) | 1999-04-30 | 2003-12-30 | Medtronic, Inc. | Closed loop medicament pump |
US6835553B2 (en) | 1999-05-11 | 2004-12-28 | M-Biotech, Inc. | Photometric glucose measurement system using glucose-sensitive hydrogel |
US6514689B2 (en) | 1999-05-11 | 2003-02-04 | M-Biotech, Inc. | Hydrogel biosensor |
US20020065682A1 (en) * | 1999-05-18 | 2002-05-30 | David M. Goldenberg | Virtual doctor interactive cybernet system |
DE19925910B4 (en) * | 1999-06-07 | 2005-04-28 | Siemens Ag | Method for processing or processing data |
US6752787B1 (en) | 1999-06-08 | 2004-06-22 | Medtronic Minimed, Inc., | Cost-sensitive application infusion device |
US6298255B1 (en) | 1999-06-09 | 2001-10-02 | Aspect Medical Systems, Inc. | Smart electrophysiological sensor system with automatic authentication and validation and an interface for a smart electrophysiological sensor system |
US6262708B1 (en) | 1999-06-16 | 2001-07-17 | Sun Microsystems, Inc. | Techniques for displaying complex characters |
GB2351153B (en) | 1999-06-18 | 2003-03-26 | Abbott Lab | Electrochemical sensor for analysis of liquid samples |
US6907127B1 (en) | 1999-06-18 | 2005-06-14 | Digital Video Express, L.P. | Hierarchical key management encoding and decoding |
FI108986B (en) | 1999-07-01 | 2002-04-30 | Emfitech Oy | Process for producing a sensor element and a sensor element |
US6368274B1 (en) | 1999-07-01 | 2002-04-09 | Medtronic Minimed, Inc. | Reusable analyte sensor site and method of using the same |
US7202734B1 (en) | 1999-07-06 | 2007-04-10 | Frederick Herbert Raab | Electronically tuned power amplifier |
US6421389B1 (en) | 1999-07-16 | 2002-07-16 | Time Domain Corporation | Baseband signal converter for a wideband impulse radio receiver |
US6160449A (en) | 1999-07-22 | 2000-12-12 | Motorola, Inc. | Power amplifying circuit with load adjust for control of adjacent and alternate channel power |
US6514460B1 (en) | 1999-07-28 | 2003-02-04 | Abbott Laboratories | Luminous glucose monitoring device |
US6899684B2 (en) | 1999-08-02 | 2005-05-31 | Healthetech, Inc. | Method of respiratory gas analysis using a metabolic calorimeter |
US6468222B1 (en) * | 1999-08-02 | 2002-10-22 | Healthetech, Inc. | Metabolic calorimeter employing respiratory gas analysis |
US7133717B2 (en) * | 1999-08-25 | 2006-11-07 | Johnson & Johnson Consumer Companies, Inc. | Tissue electroperforation for enhanced drug delivery and diagnostic sampling |
US6366793B1 (en) | 1999-09-10 | 2002-04-02 | Beckman Coulter, Inc. | Minimally invasive methods for measuring analtes in vivo |
AT408182B (en) | 1999-09-17 | 2001-09-25 | Schaupp Lukas Dipl Ing Dr Tech | DEVICE FOR VIVO MEASURING SIZES IN LIVING ORGANISMS |
WO2001028416A1 (en) | 1999-09-24 | 2001-04-26 | Healthetech, Inc. | Physiological monitor and associated computation, display and communication unit |
US6381496B1 (en) | 1999-10-01 | 2002-04-30 | Advanced Bionics Corporation | Parameter context switching for an implanted device |
US6859831B1 (en) | 1999-10-06 | 2005-02-22 | Sensoria Corporation | Method and apparatus for internetworked wireless integrated network sensor (WINS) nodes |
US20020107433A1 (en) | 1999-10-08 | 2002-08-08 | Mault James R. | System and method of personal fitness training using interactive television |
US20020062069A1 (en) | 1999-10-08 | 2002-05-23 | Mault James R. | System and method of integrated calorie management using interactive television |
US6478736B1 (en) | 1999-10-08 | 2002-11-12 | Healthetech, Inc. | Integrated calorie management system |
CA2386811A1 (en) | 1999-10-08 | 2001-04-19 | Healthetech, Inc. | Monitoring caloric expenditure rate and caloric diet |
US6612306B1 (en) | 1999-10-13 | 2003-09-02 | Healthetech, Inc. | Respiratory nitric oxide meter |
US7933780B2 (en) * | 1999-10-22 | 2011-04-26 | Telaric, Llc | Method and apparatus for controlling an infusion pump or the like |
US6228100B1 (en) | 1999-10-25 | 2001-05-08 | Steven Schraga | Multi-use lancet device |
US6954593B1 (en) | 1999-10-29 | 2005-10-11 | Matsushita Electric Industrial Co., Ltd. | Burst optical communication apparatus |
US6355369B1 (en) | 1999-10-29 | 2002-03-12 | Eontech Group, Inc. | Ecologically clean mechanically rechargeable air-metal current source |
US7645258B2 (en) * | 1999-12-01 | 2010-01-12 | B. Braun Medical, Inc. | Patient medication IV delivery pump with wireless communication to a hospital information management system |
CO5270018A1 (en) | 1999-12-11 | 2003-04-30 | Glaxo Group Ltd | MEDICINAL DISTRIBUTOR |
JP3323174B2 (en) | 1999-12-16 | 2002-09-09 | エヌイーシーネットワーク・センサ株式会社 | TDMA digital radio transmitter |
US6602191B2 (en) | 1999-12-17 | 2003-08-05 | Q-Tec Systems Llp | Method and apparatus for health and disease management combining patient data monitoring with wireless internet connectivity |
US20010053891A1 (en) | 1999-12-30 | 2001-12-20 | Ackley Donald E. | Stacked microneedle systems |
US8002700B2 (en) * | 1999-12-30 | 2011-08-23 | Medtronic, Inc. | Communications system for an implantable medical device and a delivery device |
US6961448B2 (en) | 1999-12-30 | 2005-11-01 | Medtronic, Inc. | User authentication in medical device systems |
US6513532B2 (en) * | 2000-01-19 | 2003-02-04 | Healthetech, Inc. | Diet and activity-monitoring device |
ATE552869T1 (en) * | 2000-01-21 | 2012-04-15 | Medtronic Minimed Inc | MICROPROCESSOR-CONTROLLED, AMBULATORY MEDICAL DEVICE WITH HAND-HOLD COMMUNICATION DEVICE |
US7369635B2 (en) | 2000-01-21 | 2008-05-06 | Medtronic Minimed, Inc. | Rapid discrimination preambles and methods for using the same |
US6974437B2 (en) | 2000-01-21 | 2005-12-13 | Medtronic Minimed, Inc. | Microprocessor controlled ambulatory medical apparatus with hand held communication device |
US6629934B2 (en) | 2000-02-02 | 2003-10-07 | Healthetech, Inc. | Indirect calorimeter for medical applications |
US20010037060A1 (en) | 2000-02-08 | 2001-11-01 | Thompson Richard P. | Web site for glucose monitoring |
US6818348B1 (en) | 2000-02-10 | 2004-11-16 | Ovonic Battery Company, Inc. | Nickel hydroxide paste with molasses binder |
US7003336B2 (en) | 2000-02-10 | 2006-02-21 | Medtronic Minimed, Inc. | Analyte sensor method of making the same |
US6484045B1 (en) | 2000-02-10 | 2002-11-19 | Medtronic Minimed, Inc. | Analyte sensor and method of making the same |
US20030060765A1 (en) | 2000-02-16 | 2003-03-27 | Arthur Campbell | Infusion device menu structure and method of using the same |
US6895263B2 (en) | 2000-02-23 | 2005-05-17 | Medtronic Minimed, Inc. | Real time self-adjusting calibration algorithm |
US20030154405A1 (en) * | 2000-02-28 | 2003-08-14 | John Harrison | Information processing system and method |
DE10009482C1 (en) | 2000-02-29 | 2001-08-23 | Disetronic Licensing Ag | Device for isolating one or more components from body fluid comprises cannula which is inserted into tissue and is connected at top of capillary layer which has free surface from which liquid can evaporate |
US6893396B2 (en) | 2000-03-01 | 2005-05-17 | I-Medik, Inc. | Wireless internet bio-telemetry monitoring system and interface |
US6350663B1 (en) | 2000-03-03 | 2002-02-26 | Agilent Technologies, Inc. | Method for reducing leakage currents of active area diodes and source/drain diffusions |
US6461329B1 (en) | 2000-03-13 | 2002-10-08 | Medtronic Minimed, Inc. | Infusion site leak detection system and method of using the same |
US6405066B1 (en) | 2000-03-17 | 2002-06-11 | The Regents Of The University Of California | Implantable analyte sensor |
BR0001404A (en) | 2000-03-23 | 2001-11-13 | Brasil Compressores Sa | Position sensor and compressor |
US6485465B2 (en) | 2000-03-29 | 2002-11-26 | Medtronic Minimed, Inc. | Methods, apparatuses, and uses for infusion pump fluid pressure and force detection |
US6485461B1 (en) | 2000-04-04 | 2002-11-26 | Insulet, Inc. | Disposable infusion device |
US6623501B2 (en) | 2000-04-05 | 2003-09-23 | Therasense, Inc. | Reusable ceramic skin-piercing device |
US6610012B2 (en) * | 2000-04-10 | 2003-08-26 | Healthetech, Inc. | System and method for remote pregnancy monitoring |
JP2001297153A (en) * | 2000-04-14 | 2001-10-26 | Nec Corp | Sharing method and database terminal for personal medical information |
US6201721B1 (en) | 2000-04-26 | 2001-03-13 | Lucent Technologies Inc. | Bus holdup circuit for a distributed power system and method of operation thereof |
IT1314759B1 (en) | 2000-05-08 | 2003-01-03 | Menarini Farma Ind | INSTRUMENTATION FOR MEASUREMENT AND CONTROL OF THE CONTENT OF GLUCOSIOLACTATE OR OTHER METABOLITES IN BIOLOGICAL FLUIDS |
AU2001263022A1 (en) | 2000-05-12 | 2001-11-26 | Therasense, Inc. | Electrodes with multilayer membranes and methods of using and making the electrodes |
US6442413B1 (en) | 2000-05-15 | 2002-08-27 | James H. Silver | Implantable sensor |
US7181261B2 (en) | 2000-05-15 | 2007-02-20 | Silver James H | Implantable, retrievable, thrombus minimizing sensors |
US7006858B2 (en) | 2000-05-15 | 2006-02-28 | Silver James H | Implantable, retrievable sensors and immunosensors |
US9427520B2 (en) | 2005-02-11 | 2016-08-30 | Carefusion 303, Inc. | Management of pending medication orders |
US6482158B2 (en) | 2000-05-19 | 2002-11-19 | Healthetech, Inc. | System and method of ultrasonic mammography |
EP1284642A4 (en) | 2000-05-25 | 2005-03-09 | Healthetech Inc | Physiological monitoring using wrist-mounted device |
EP1283689A4 (en) | 2000-05-25 | 2005-03-09 | Healthetech Inc | Weight control method using physical activity based parameters |
US20020013551A1 (en) * | 2000-05-26 | 2002-01-31 | Akinori Zaitsu | Medical pump monitoring system |
US6506168B1 (en) | 2000-05-26 | 2003-01-14 | Abbott Laboratories | Apparatus and method for obtaining blood for diagnostic tests |
TW499314B (en) * | 2000-05-30 | 2002-08-21 | Novo Nordisk As | A medication delivery device with replaceable cooperating modules and a method of making same |
AU2001260710A1 (en) | 2000-06-02 | 2001-12-11 | Arkray, Inc. | Measurement device, and measured data transmitting method |
WO2001093743A2 (en) | 2000-06-07 | 2001-12-13 | Healthetech, Inc. | Breath ketone analyzer |
IL153516A (en) * | 2000-06-23 | 2007-07-24 | Bodymedia Inc | System for monitoring health, wellness and fitness |
US6540675B2 (en) | 2000-06-27 | 2003-04-01 | Rosedale Medical, Inc. | Analyte monitor |
US6589229B1 (en) | 2000-07-31 | 2003-07-08 | Becton, Dickinson And Company | Wearable, self-contained drug infusion device |
WO2002012251A1 (en) | 2000-08-04 | 2002-02-14 | Sensors For Medicine And Science, Inc. | Detection of analytes in aqueous environments |
KR100488515B1 (en) | 2000-08-04 | 2005-05-11 | 삼성전자주식회사 | Computer |
JP2002055076A (en) | 2000-09-08 | 2002-02-20 | Nec Corp | Electrochemical sensor |
JP4055926B2 (en) * | 2000-08-14 | 2008-03-05 | テルモ株式会社 | Infusion pump |
US6475196B1 (en) | 2000-08-18 | 2002-11-05 | Minimed Inc. | Subcutaneous infusion cannula |
WO2002017210A2 (en) | 2000-08-18 | 2002-02-28 | Cygnus, Inc. | Formulation and manipulation of databases of analyte and associated values |
US20020026937A1 (en) * | 2000-08-28 | 2002-03-07 | Mault James R. | Respiratory gas sensors in folw path |
US6591139B2 (en) | 2000-09-06 | 2003-07-08 | Advanced Bionics Corporation | Low-power, high-modulation-index amplifier for use in battery-powered device |
US20020047867A1 (en) | 2000-09-07 | 2002-04-25 | Mault James R | Image based diet logging |
ES2287156T3 (en) | 2000-09-08 | 2007-12-16 | Insulet Corporation | DEVICES AND SYSTEMS FOR THE INFUSION OF A PATIENT. |
US6669669B2 (en) | 2001-10-12 | 2003-12-30 | Insulet Corporation | Laminated patient infusion device |
WO2002023452A1 (en) * | 2000-09-12 | 2002-03-21 | American Express Travel Related Services Company, Inc. | Microchip-enabled online transaction system |
US20020124017A1 (en) | 2000-09-22 | 2002-09-05 | Mault James R. | Personal digital assistant with food scale accessory |
US20020103425A1 (en) | 2000-09-27 | 2002-08-01 | Mault James R. | self-contained monitoring device particularly useful for monitoring physiological conditions |
US6650064B2 (en) | 2000-09-29 | 2003-11-18 | Aerospace Optics, Inc. | Fault tolerant led display design |
AU2001296456A1 (en) | 2000-09-29 | 2002-04-08 | Healthetech, Inc. | Indirect calorimetry system |
AU9658801A (en) | 2000-10-04 | 2002-04-15 | Insulet Corp | Data collection assembly for patient infusion system |
US20120191052A1 (en) * | 2000-10-06 | 2012-07-26 | Ip Holdings, Inc. | Intelligent activated skin patch system |
EP1339312B1 (en) | 2000-10-10 | 2006-01-04 | Microchips, Inc. | Microchip reservoir devices using wireless transmission of power and data |
US6537243B1 (en) * | 2000-10-12 | 2003-03-25 | Abbott Laboratories | Device and method for obtaining interstitial fluid from a patient for diagnostic tests |
US20020133378A1 (en) | 2000-10-13 | 2002-09-19 | Mault James R. | System and method of integrated calorie management |
US7198603B2 (en) | 2003-04-14 | 2007-04-03 | Remon Medical Technologies, Inc. | Apparatus and methods using acoustic telemetry for intrabody communications |
WO2002047465A2 (en) | 2000-10-26 | 2002-06-20 | Healthetech, Inc. | Body supported activity and condition monitor |
EP1702635B1 (en) | 2000-11-09 | 2008-01-16 | Insulet Corporation | Transcutaneous delivery means |
JP2004512914A (en) | 2000-11-13 | 2004-04-30 | ニプロ ダイアベッツ システムズ | Glucose sensor system |
US6832114B1 (en) | 2000-11-21 | 2004-12-14 | Advanced Bionics Corporation | Systems and methods for modulation of pancreatic endocrine secretion and treatment of diabetes |
US7230071B1 (en) | 2000-11-27 | 2007-06-12 | United States Of America As Represented By The Secretary Of The Army | Methods for polymerization of electronic and photonic polymers |
WO2002043590A1 (en) * | 2000-11-30 | 2002-06-06 | Arkray, Inc. | Measuring device equipped with comment input function |
US6645142B2 (en) | 2000-12-01 | 2003-11-11 | Optiscan Biomedical Corporation | Glucose monitoring instrument having network connectivity |
US20020077766A1 (en) | 2000-12-11 | 2002-06-20 | Mault James R. | Remote temperature monitoring system |
GB0030929D0 (en) * | 2000-12-19 | 2001-01-31 | Inverness Medical Ltd | Analyte measurement |
US20020118090A1 (en) | 2000-12-20 | 2002-08-29 | Byong-Ho Park | Shape memory alloy actuators activated by strain gradient variation during phase transformation |
DE60115707T2 (en) | 2000-12-21 | 2006-08-10 | Insulet Corp., Beverly | REMOTE CONTROL MEDICAL DEVICE |
US8050625B2 (en) * | 2000-12-22 | 2011-11-01 | Terahop Networks, Inc. | Wireless reader tags (WRTs) with sensor components in asset monitoring and tracking systems |
US6471980B2 (en) | 2000-12-22 | 2002-10-29 | Avantec Vascular Corporation | Intravascular delivery of mycophenolic acid |
US6560471B1 (en) | 2001-01-02 | 2003-05-06 | Therasense, Inc. | Analyte monitoring device and methods of use |
WO2002054052A1 (en) | 2001-01-08 | 2002-07-11 | Leonard Fish | Diagnostic instruments and methods for detecting analytes |
WO2002057627A1 (en) | 2001-01-17 | 2002-07-25 | M 2 Medical A/S | Shape memory alloy actuator |
US20020099568A1 (en) * | 2001-01-23 | 2002-07-25 | Turner Kathryn C. | System and method for facilitating the coordination of care of an individual and dissemination of information |
CA2434731C (en) | 2001-02-22 | 2010-01-26 | Insulet Corporation | Modular infusion device and method |
DE10108732A1 (en) | 2001-02-23 | 2002-09-05 | Philips Corp Intellectual Pty | Device with a magnetic position sensor |
US6525330B2 (en) * | 2001-02-28 | 2003-02-25 | Home Diagnostics, Inc. | Method of strip insertion detection |
WO2002071305A2 (en) | 2001-03-08 | 2002-09-12 | Framtidartaekni Ehf. | On-line health monitoring |
US6799861B2 (en) | 2001-03-15 | 2004-10-05 | Technology Creations, Inc. | Portable lighting apparatus and method of use |
US6952603B2 (en) | 2001-03-16 | 2005-10-04 | Roche Diagnostics Operations, Inc. | Subcutaneous analyte sensor |
US6453195B1 (en) * | 2001-03-19 | 2002-09-17 | Medtronic, Inc. | Closed loop drug delivery system and remote management thereof |
US6898451B2 (en) | 2001-03-21 | 2005-05-24 | Minformed, L.L.C. | Non-invasive blood analyte measuring system and method utilizing optical absorption |
US7324949B2 (en) * | 2001-03-26 | 2008-01-29 | Medtronic, Inc. | Implantable medical device management system |
AU2002255953A1 (en) | 2001-03-27 | 2002-10-08 | Aron Z. Kain | Wireless system for measuring distension in flexible tubes |
GB0108228D0 (en) | 2001-04-02 | 2001-05-23 | Glaxo Group Ltd | Medicament dispenser |
US7041468B2 (en) | 2001-04-02 | 2006-05-09 | Therasense, Inc. | Blood glucose tracking apparatus and methods |
US6854620B2 (en) | 2001-04-13 | 2005-02-15 | Nipro Diabetes, Systems, Inc. | Drive system for an infusion pump |
FR2823618B1 (en) | 2001-04-13 | 2003-05-30 | Electricite De France | STAGE OF A HIGH FREQUENCY CURRENT POWER GENERATOR |
US7083593B2 (en) | 2001-04-18 | 2006-08-01 | Advanced Bionics Corporation | Programmable implantable pump with accessory reservoirs and multiple independent lumen catheter |
US6551345B2 (en) | 2001-04-26 | 2003-04-22 | Alfred E. Mann Foundation For Scientific Research | Protection apparatus for implantable medical device |
US20030208409A1 (en) | 2001-04-30 | 2003-11-06 | Mault James R. | Method and apparatus for diet control |
US20020165732A1 (en) * | 2001-05-02 | 2002-11-07 | Matchmd, Llc | System and method for automated and interactive scheduling |
DE60214375T2 (en) | 2001-05-18 | 2007-08-30 | Polymer Technology Systems, Inc., Indianapolis | DEVICE FOR EXAMINING BODY FLUIDS WITH SOLVENTLY FIXED, PORTABLE TEST DEVICE |
US6549796B2 (en) | 2001-05-25 | 2003-04-15 | Lifescan, Inc. | Monitoring analyte concentration using minimally invasive devices |
US6582393B2 (en) | 2001-05-29 | 2003-06-24 | Therafuse, Inc. | Compensating drug delivery system |
US20040019321A1 (en) | 2001-05-29 | 2004-01-29 | Sage Burton H. | Compensating drug delivery system |
DK1395128T4 (en) | 2001-05-31 | 2011-10-24 | Abbott Lab | Acid controlled viscosity fiber system and applications thereof |
AU2002345757A1 (en) | 2001-06-11 | 2002-12-23 | Glaxo Group Limited | Medicament dispenser for containers of varying sizes |
GB0114290D0 (en) | 2001-06-12 | 2001-08-01 | Iit Ltd | Analytical devices kits and methods of use |
US6472991B1 (en) | 2001-06-15 | 2002-10-29 | Alfred E. Mann Foundation For Scientific Research | Multichannel communication protocol configured to extend the battery life of an implantable device |
WO2003000127A2 (en) | 2001-06-22 | 2003-01-03 | Cygnus, Inc. | Method for improving the performance of an analyte monitoring system |
EP1403795A4 (en) | 2001-06-22 | 2007-08-01 | Arkray Inc | Information communication system |
US20030040683A1 (en) * | 2001-07-06 | 2003-02-27 | Peter Rule | Site selection for determining analyte concentration in living tissue |
US20030032868A1 (en) * | 2001-07-09 | 2003-02-13 | Henning Graskov | Method and system for controlling data information between two portable apparatuses |
AUPR632301A0 (en) | 2001-07-11 | 2001-08-02 | Chee, Frederick Howe-Hui | Infusion apparatus for regulating blood glucose levels |
US20030208113A1 (en) | 2001-07-18 | 2003-11-06 | Mault James R | Closed loop glycemic index system |
US20030023182A1 (en) * | 2001-07-26 | 2003-01-30 | Mault James R. | Respiratory connector for respiratory gas analysis |
US6702857B2 (en) | 2001-07-27 | 2004-03-09 | Dexcom, Inc. | Membrane for use with implantable devices |
US20030032874A1 (en) | 2001-07-27 | 2003-02-13 | Dexcom, Inc. | Sensor head for use with implantable devices |
US6544212B2 (en) * | 2001-07-31 | 2003-04-08 | Roche Diagnostics Corporation | Diabetes management system |
US6788965B2 (en) | 2001-08-03 | 2004-09-07 | Sensys Medical, Inc. | Intelligent system for detecting errors and determining failure modes in noninvasive measurement of blood and tissue analytes |
US20050226918A1 (en) * | 2001-08-13 | 2005-10-13 | Macdonald Stuart G | Delivery system for insulin and other therapeutic agents |
EP1320322A1 (en) * | 2001-08-20 | 2003-06-25 | Inverness Medical Limited | Wireless diabetes management devices and methods for using the same |
US7025760B2 (en) | 2001-09-07 | 2006-04-11 | Medtronic Minimed, Inc. | Method and system for non-vascular sensor implantation |
US20030055380A1 (en) * | 2001-09-19 | 2003-03-20 | Flaherty J. Christopher | Plunger for patient infusion device |
WO2003030731A2 (en) | 2001-10-09 | 2003-04-17 | Optiscan Biomedical Corporation | Method and apparatus for improving clinical accuracy of analyte measurements |
US7854230B2 (en) | 2001-10-22 | 2010-12-21 | O.R. Solutions, Inc. | Heated medical instrument stand with surgical drape and method of detecting fluid and leaks in the stand tray |
US7010356B2 (en) | 2001-10-31 | 2006-03-07 | London Health Sciences Centre Research Inc. | Multichannel electrode and methods of using same |
AU2002356956A1 (en) | 2001-11-16 | 2003-06-10 | North Carolina State University | Biomedical electrochemical sensor array and method of fabrication |
US20030175806A1 (en) | 2001-11-21 | 2003-09-18 | Peter Rule | Method and apparatus for improving the accuracy of alternative site analyte concentration measurements |
US20030105407A1 (en) | 2001-11-30 | 2003-06-05 | Pearce, Edwin M. | Disposable flow tube for respiratory gas analysis |
PT1642608E (en) | 2001-12-06 | 2011-07-25 | Carefusion 303 Inc | Co2 monitored drug infusion system |
WO2003049609A1 (en) | 2001-12-07 | 2003-06-19 | Micronix, Inc. | Consolidated body fluid testing device and method |
US20030107487A1 (en) | 2001-12-10 | 2003-06-12 | Ronen Korman | Method and device for measuring physiological parameters at the wrist |
US6586971B1 (en) | 2001-12-18 | 2003-07-01 | Hewlett-Packard Development Company, L.P. | Adapting VLSI clocking to short term voltage transients |
US7022072B2 (en) | 2001-12-27 | 2006-04-04 | Medtronic Minimed, Inc. | System for monitoring physiological characteristics |
US7399277B2 (en) * | 2001-12-27 | 2008-07-15 | Medtronic Minimed, Inc. | System for monitoring physiological characteristics |
US7317967B2 (en) * | 2001-12-31 | 2008-01-08 | B. Braun Medical Inc. | Apparatus and method for transferring data to a pharmaceutical compounding system |
US7343224B2 (en) * | 2001-12-31 | 2008-03-11 | B. Braun Medical Inc. | Pharmaceutical compounding systems and methods and information management system for same |
US20030130866A1 (en) * | 2002-01-08 | 2003-07-10 | Turner Kathryn C. | System and method for facilitating the care of an individual and dissemination of infromation |
US6543224B1 (en) | 2002-01-29 | 2003-04-08 | United Technologies Corporation | System and method for controlling shape memory alloy actuators |
US7153212B1 (en) | 2002-02-01 | 2006-12-26 | Mad Catz, Inc. | Light attachment for portable electronic device |
US9247901B2 (en) * | 2003-08-22 | 2016-02-02 | Dexcom, Inc. | Systems and methods for replacing signal artifacts in a glucose sensor data stream |
US8260393B2 (en) | 2003-07-25 | 2012-09-04 | Dexcom, Inc. | Systems and methods for replacing signal data artifacts in a glucose sensor data stream |
US7613491B2 (en) | 2002-05-22 | 2009-11-03 | Dexcom, Inc. | Silicone based membranes for use in implantable glucose sensors |
US8010174B2 (en) | 2003-08-22 | 2011-08-30 | Dexcom, Inc. | Systems and methods for replacing signal artifacts in a glucose sensor data stream |
US8364229B2 (en) | 2003-07-25 | 2013-01-29 | Dexcom, Inc. | Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise |
US7024249B2 (en) | 2002-02-21 | 2006-04-04 | Alfred E. Mann Foundation For Scientific Research | Pulsed magnetic control system for interlocking functions of battery powered living tissue stimulators |
US6839596B2 (en) | 2002-02-21 | 2005-01-04 | Alfred E. Mann Foundation For Scientific Research | Magnet control system for battery powered living tissue stimulators |
US20030212379A1 (en) | 2002-02-26 | 2003-11-13 | Bylund Adam David | Systems and methods for remotely controlling medication infusion and analyte monitoring |
US20080172026A1 (en) * | 2006-10-17 | 2008-07-17 | Blomquist Michael L | Insulin pump having a suspension bolus |
US6692457B2 (en) | 2002-03-01 | 2004-02-17 | Insulet Corporation | Flow condition sensor assembly for patient infusion device |
US6830558B2 (en) | 2002-03-01 | 2004-12-14 | Insulet Corporation | Flow condition sensor assembly for patient infusion device |
US6908535B2 (en) | 2002-03-06 | 2005-06-21 | Medtronic, Inc. | Current-to-voltage-converter for a biosensor |
EP1499231A4 (en) | 2002-03-08 | 2007-09-26 | Sensys Medical Inc | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy |
CA2478822C (en) | 2002-03-11 | 2016-07-12 | Altea Therapeutics Corporation | Transdermal drug delivery patch system, method of making same and method of using same |
GB0206792D0 (en) | 2002-03-22 | 2002-05-01 | Leuven K U Res & Dev | Normoglycemia |
DE60334365D1 (en) | 2002-03-22 | 2010-11-11 | Animas Technologies Llc | INCREASED PERFORMANCE OF AN ANALYSIS MONITORING DEVICE |
US6936006B2 (en) | 2002-03-22 | 2005-08-30 | Novo Nordisk, A/S | Atraumatic insertion of a subcutaneous device |
US6990372B2 (en) | 2002-04-11 | 2006-01-24 | Alfred E. Mann Foundation For Scientific Research | Programmable signal analysis device for detecting neurological signals in an implantable device |
US7371247B2 (en) | 2002-04-19 | 2008-05-13 | Pelikan Technologies, Inc | Method and apparatus for penetrating tissue |
US7052251B2 (en) | 2002-04-22 | 2006-05-30 | Medtronic Minimed, Inc. | Shape memory alloy wire driven positive displacement micropump with pulsatile output |
US7153265B2 (en) | 2002-04-22 | 2006-12-26 | Medtronic Minimed, Inc. | Anti-inflammatory biosensor for reduced biofouling and enhanced sensor performance |
US20030232370A1 (en) | 2002-04-22 | 2003-12-18 | Trifiro Mark A. | Glucose sensor and uses thereof |
US6656159B2 (en) | 2002-04-23 | 2003-12-02 | Insulet Corporation | Dispenser for patient infusion device |
US20040153032A1 (en) | 2002-04-23 | 2004-08-05 | Garribotto John T. | Dispenser for patient infusion device |
US6656158B2 (en) | 2002-04-23 | 2003-12-02 | Insulet Corporation | Dispenser for patient infusion device |
US6960192B1 (en) | 2002-04-23 | 2005-11-01 | Insulet Corporation | Transcutaneous fluid delivery system |
US20050238507A1 (en) | 2002-04-23 | 2005-10-27 | Insulet Corporation | Fluid delivery device |
US6946299B2 (en) | 2002-04-25 | 2005-09-20 | Home Diagnostics, Inc. | Systems and methods for blood glucose sensing |
US6743635B2 (en) | 2002-04-25 | 2004-06-01 | Home Diagnostics, Inc. | System and methods for blood glucose sensing |
US6758835B2 (en) | 2002-05-01 | 2004-07-06 | Medtg, Llc | Disposable needle assembly having sensors formed therein permitting the simultaneous drawing and administering of fluids and method of forming the same |
US7286997B2 (en) * | 2002-05-07 | 2007-10-23 | Cembex Care Solutions, Llc | Internet-based, customizable clinical information system |
US7343188B2 (en) | 2002-05-09 | 2008-03-11 | Lifescan, Inc. | Devices and methods for accessing and analyzing physiological fluid |
US7060192B2 (en) | 2002-05-09 | 2006-06-13 | Lifescan, Inc. | Methods of fabricating physiological sample collection devices |
US6801041B2 (en) | 2002-05-14 | 2004-10-05 | Abbott Laboratories | Sensor having electrode for determining the rate of flow of a fluid |
CA2486129C (en) * | 2002-05-16 | 2010-09-21 | Scott Laboratories, Inc. | User authorization system and method for a sedation and analgesia system |
US7226978B2 (en) | 2002-05-22 | 2007-06-05 | Dexcom, Inc. | Techniques to improve polyurethane membranes for implantable glucose sensors |
US6723072B2 (en) | 2002-06-06 | 2004-04-20 | Insulet Corporation | Plunger assembly for patient infusion device |
US20080132842A1 (en) | 2002-06-06 | 2008-06-05 | Flaherty J Christopher | Plunger assembly for patient infusion device |
WO2003104997A1 (en) * | 2002-06-10 | 2003-12-18 | 株式会社エヌ・ティ・ティ・ドコモ | Ic card, terminal device, and data communication method |
US20040172290A1 (en) * | 2002-07-15 | 2004-09-02 | Samuel Leven | Health monitoring device |
US20040010207A1 (en) * | 2002-07-15 | 2004-01-15 | Flaherty J. Christopher | Self-contained, automatic transcutaneous physiologic sensing system |
US7018360B2 (en) | 2002-07-16 | 2006-03-28 | Insulet Corporation | Flow restriction system and method for patient infusion device |
AU2003302720B9 (en) | 2002-07-19 | 2008-08-21 | Smiths Detection-Pasadena, Inc. | Non-specific sensor array detectors |
US7278983B2 (en) | 2002-07-24 | 2007-10-09 | Medtronic Minimed, Inc. | Physiological monitoring device for controlling a medication infusion device |
US20040068230A1 (en) | 2002-07-24 | 2004-04-08 | Medtronic Minimed, Inc. | System for providing blood glucose measurements to an infusion device |
US8512276B2 (en) | 2002-07-24 | 2013-08-20 | Medtronic Minimed, Inc. | System for providing blood glucose measurements to an infusion device |
US20040027253A1 (en) | 2002-08-12 | 2004-02-12 | Marsh Douglas G. | Automatic reading of a meter having a dial or numeric visual display |
WO2004015539A2 (en) | 2002-08-13 | 2004-02-19 | University Of Virginia Patent Foundation | Managing and processing self-monitoring blood glucose |
US7020508B2 (en) | 2002-08-22 | 2006-03-28 | Bodymedia, Inc. | Apparatus for detecting human physiological and contextual information |
US20050118726A1 (en) | 2002-08-26 | 2005-06-02 | Schultz Jerome S. | System and method for detecting bioanalytes and method for producing a bioanalyte sensor |
US6865641B2 (en) * | 2002-08-29 | 2005-03-08 | International Business Machines Corporation | Method and apparatus for non-volatile display of information for an electronic device |
ES2384558T3 (en) * | 2002-09-11 | 2012-07-06 | Becton Dickinson And Company | Blood glucose monitoring including convenient visual presentation of averages and measurement values |
JP2005538773A (en) | 2002-09-12 | 2005-12-22 | チルドレンズ ホスピタル メディカル センター | Method and apparatus for injecting drugs without pain |
US7070591B2 (en) | 2002-09-17 | 2006-07-04 | Transoma Medical, Inc. | Vascular access port with physiological sensor |
US7998107B2 (en) * | 2002-09-24 | 2011-08-16 | Kensey Nash Corporation | Interventional procedure drive and control system |
US7323091B1 (en) | 2002-09-24 | 2008-01-29 | Orion Research, Inc. | Multimode electrochemical sensing array |
US7736309B2 (en) | 2002-09-27 | 2010-06-15 | Medtronic Minimed, Inc. | Implantable sensor method and system |
US7144384B2 (en) | 2002-09-30 | 2006-12-05 | Insulet Corporation | Dispenser components and methods for patient infusion device |
US6770729B2 (en) | 2002-09-30 | 2004-08-03 | Medtronic Minimed, Inc. | Polymer compositions containing bioactive agents and methods for their use |
US7128727B2 (en) | 2002-09-30 | 2006-10-31 | Flaherty J Christopher | Components and methods for patient infusion device |
US7211048B1 (en) | 2002-10-07 | 2007-05-01 | Integrated Sensing Systems, Inc. | System for monitoring conduit obstruction |
US7993108B2 (en) | 2002-10-09 | 2011-08-09 | Abbott Diabetes Care Inc. | Variable volume, shape memory actuated insulin dispensing pump |
EP2322798A1 (en) | 2002-10-09 | 2011-05-18 | Abbott Diabetes Care Inc. | Device and method for delivering medical fluids using a shape memory alloy |
US7399401B2 (en) | 2002-10-09 | 2008-07-15 | Abbott Diabetes Care, Inc. | Methods for use in assessing a flow condition of a fluid |
US7727181B2 (en) | 2002-10-09 | 2010-06-01 | Abbott Diabetes Care Inc. | Fluid delivery device with autocalibration |
JP4599296B2 (en) | 2002-10-11 | 2010-12-15 | ベクトン・ディキンソン・アンド・カンパニー | System and method for initiating and maintaining continuous long-term control of the concentration of a substance in a patient's body using a feedback or model-based controller coupled to a single needle or multi-needle intradermal (ID) delivery device |
US7964390B2 (en) * | 2002-10-11 | 2011-06-21 | Case Western Reserve University | Sensor system |
US20040108226A1 (en) | 2002-10-28 | 2004-06-10 | Constantin Polychronakos | Continuous glucose quantification device and method |
US7381184B2 (en) | 2002-11-05 | 2008-06-03 | Abbott Diabetes Care Inc. | Sensor inserter assembly |
US20040100376A1 (en) | 2002-11-26 | 2004-05-27 | Kimberly-Clark Worldwide, Inc. | Healthcare monitoring system |
US20040116866A1 (en) | 2002-12-17 | 2004-06-17 | William Gorman | Skin attachment apparatus and method for patient infusion device |
US20050038680A1 (en) | 2002-12-19 | 2005-02-17 | Mcmahon Kevin Lee | System and method for glucose monitoring |
US20040122353A1 (en) | 2002-12-19 | 2004-06-24 | Medtronic Minimed, Inc. | Relay device for transferring information between a sensor system and a fluid delivery system |
US20040254884A1 (en) | 2002-12-20 | 2004-12-16 | Sap Aktiengesellschaft | Content catalog and application designer framework |
US7127300B2 (en) * | 2002-12-23 | 2006-10-24 | Cardiac Pacemakers, Inc. | Method and apparatus for enabling data communication between an implantable medical device and a patient management system |
US7811231B2 (en) | 2002-12-31 | 2010-10-12 | Abbott Diabetes Care Inc. | Continuous glucose monitoring system and methods of use |
US8771183B2 (en) | 2004-02-17 | 2014-07-08 | Abbott Diabetes Care Inc. | Method and system for providing data communication in continuous glucose monitoring and management system |
US7154398B2 (en) | 2003-01-06 | 2006-12-26 | Chen Thomas C H | Wireless communication and global location enabled intelligent health monitoring system |
US7149581B2 (en) | 2003-01-31 | 2006-12-12 | Medtronic, Inc. | Patient monitoring device with multi-antenna receiver |
TWI236611B (en) * | 2003-02-01 | 2005-07-21 | Baxter Int | Medical data communication notification and messaging system and method |
US20040164961A1 (en) | 2003-02-21 | 2004-08-26 | Debasis Bal | Method, system and computer product for continuously monitoring data sources for an event of interest |
WO2004088304A2 (en) | 2003-04-01 | 2004-10-14 | Piet Moerman | Method and device for utilizing analyte levels to assist in the treatment of diabetes, insulin resistance and metabolic syndrome |
US7587287B2 (en) | 2003-04-04 | 2009-09-08 | Abbott Diabetes Care Inc. | Method and system for transferring analyte test data |
US7134999B2 (en) | 2003-04-04 | 2006-11-14 | Dexcom, Inc. | Optimized sensor geometry for an implantable glucose sensor |
US20050038674A1 (en) | 2003-04-15 | 2005-02-17 | Braig James R. | System and method for managing a chronic medical condition |
US7136704B2 (en) | 2003-04-16 | 2006-11-14 | Alfred E. Mann Foundation For Scientific Research | Blood oxygen monitoring system and a lead therefor |
US20050182366A1 (en) | 2003-04-18 | 2005-08-18 | Insulet Corporation | Method For Visual Output Verification |
JP2007525241A (en) | 2003-04-18 | 2007-09-06 | インシュレット コーポレイション | User interface for infusion pump remote control and method of use thereof |
US7679407B2 (en) | 2003-04-28 | 2010-03-16 | Abbott Diabetes Care Inc. | Method and apparatus for providing peak detection circuitry for data communication systems |
AU2004235793A1 (en) | 2003-04-30 | 2004-11-18 | Insulet Corporation | RF medical device |
US7266400B2 (en) | 2003-05-06 | 2007-09-04 | Orsense Ltd. | Glucose level control method and system |
KR100504766B1 (en) | 2003-05-07 | 2005-07-29 | 주식회사 아이센스 | Blood glucose test meter having each measuring means at its both ends |
US7875293B2 (en) | 2003-05-21 | 2011-01-25 | Dexcom, Inc. | Biointerface membranes incorporating bioactive agents |
DE10325106A1 (en) * | 2003-06-03 | 2004-12-30 | Disetronic Licensing Ag | Device and method for recognizing a user of a medical device |
US20040249250A1 (en) | 2003-06-04 | 2004-12-09 | Mcgee Michael D. | System and apparatus for monitoring and prompting medical self-care events and communicating medical self-care status |
US7258673B2 (en) | 2003-06-06 | 2007-08-21 | Lifescan, Inc | Devices, systems and methods for extracting bodily fluid and monitoring an analyte therein |
US20040253736A1 (en) | 2003-06-06 | 2004-12-16 | Phil Stout | Analytical device with prediction module and related methods |
DK1633235T3 (en) | 2003-06-06 | 2014-08-18 | Sanofi Aventis Deutschland | Apparatus for sampling body fluid and detecting analyte |
US20050016276A1 (en) | 2003-06-06 | 2005-01-27 | Palo Alto Sensor Technology Innovation | Frequency encoding of resonant mass sensors |
US20040249254A1 (en) | 2003-06-06 | 2004-12-09 | Joel Racchini | Devices, systems and methods for extracting bodily fluid and monitoring an analyte therein |
US8460243B2 (en) | 2003-06-10 | 2013-06-11 | Abbott Diabetes Care Inc. | Glucose measuring module and insulin pump combination |
US8066639B2 (en) | 2003-06-10 | 2011-11-29 | Abbott Diabetes Care Inc. | Glucose measuring device for use in personal area network |
US7406716B2 (en) * | 2003-06-10 | 2008-07-29 | Kabushiki Kaisha Toshiba | Software IP providing system and method, software IP obtaining method, and IP core designing and manufacturing method |
US20040254429A1 (en) | 2003-06-11 | 2004-12-16 | Health & Life Co., Ltd. | Data storage device for integrating data of several medical measuring instruments |
US8071028B2 (en) | 2003-06-12 | 2011-12-06 | Abbott Diabetes Care Inc. | Method and apparatus for providing power management in data communication systems |
US20040264396A1 (en) | 2003-06-30 | 2004-12-30 | Boris Ginzburg | Method for power saving in a wireless LAN |
US7424318B2 (en) | 2003-12-05 | 2008-09-09 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
US7108778B2 (en) | 2003-07-25 | 2006-09-19 | Dexcom, Inc. | Electrochemical sensors including electrode systems with increased oxygen generation |
US8423113B2 (en) | 2003-07-25 | 2013-04-16 | Dexcom, Inc. | Systems and methods for processing sensor data |
JP4708342B2 (en) | 2003-07-25 | 2011-06-22 | デックスコム・インコーポレーテッド | Oxygen augmentation membrane system for use in implantable devices |
US7460898B2 (en) | 2003-12-05 | 2008-12-02 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
US7761130B2 (en) | 2003-07-25 | 2010-07-20 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
US8282549B2 (en) | 2003-12-09 | 2012-10-09 | Dexcom, Inc. | Signal processing for continuous analyte sensor |
US7467003B2 (en) | 2003-12-05 | 2008-12-16 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
US20050176136A1 (en) | 2003-11-19 | 2005-08-11 | Dexcom, Inc. | Afinity domain for analyte sensor |
US7366556B2 (en) * | 2003-12-05 | 2008-04-29 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
US7651596B2 (en) | 2005-04-08 | 2010-01-26 | Dexcom, Inc. | Cellulosic-based interference domain for an analyte sensor |
JP2007500336A (en) | 2003-07-25 | 2007-01-11 | デックスコム・インコーポレーテッド | Electrode system for electrochemical sensors |
US7186566B2 (en) | 2003-07-28 | 2007-03-06 | Suyue Qian | Combining transmittance detection and chromatographic strip techniques for quantification of analyte in biological fluids |
US8886273B2 (en) | 2003-08-01 | 2014-11-11 | Dexcom, Inc. | Analyte sensor |
US7591801B2 (en) | 2004-02-26 | 2009-09-22 | Dexcom, Inc. | Integrated delivery device for continuous glucose sensor |
US8369919B2 (en) | 2003-08-01 | 2013-02-05 | Dexcom, Inc. | Systems and methods for processing sensor data |
US8626257B2 (en) | 2003-08-01 | 2014-01-07 | Dexcom, Inc. | Analyte sensor |
US8060173B2 (en) | 2003-08-01 | 2011-11-15 | Dexcom, Inc. | System and methods for processing analyte sensor data |
US8275437B2 (en) | 2003-08-01 | 2012-09-25 | Dexcom, Inc. | Transcutaneous analyte sensor |
US9135402B2 (en) | 2007-12-17 | 2015-09-15 | Dexcom, Inc. | Systems and methods for processing sensor data |
US7774145B2 (en) | 2003-08-01 | 2010-08-10 | Dexcom, Inc. | Transcutaneous analyte sensor |
US6899695B2 (en) * | 2003-08-08 | 2005-05-31 | Hector J. Herrera | Medication security apparatus and method |
US8233959B2 (en) | 2003-08-22 | 2012-07-31 | Dexcom, Inc. | Systems and methods for processing analyte sensor data |
US8346482B2 (en) * | 2003-08-22 | 2013-01-01 | Fernandez Dennis S | Integrated biosensor and simulation system for diagnosis and therapy |
US9133024B2 (en) * | 2003-09-03 | 2015-09-15 | Brigitte Chau Phan | Personal diagnostic devices including related methods and systems |
US7205409B2 (en) | 2003-09-04 | 2007-04-17 | Abbott Laboratories | Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV) |
EP3851030B1 (en) | 2003-09-11 | 2024-01-17 | Labrador Diagnostics LLC | Medical device for analyte monitoring |
US7361155B2 (en) | 2003-09-16 | 2008-04-22 | Therafuse, Inc. | Compensating liquid delivery system and method |
DE10343863A1 (en) | 2003-09-23 | 2005-04-14 | Roche Diagnostics Gmbh | Method and device for continuously monitoring the concentration of an analyte |
WO2005036304A2 (en) * | 2003-09-29 | 2005-04-21 | Realm Systems, Inc. | Mobility device server |
DE602004026763D1 (en) * | 2003-09-30 | 2010-06-02 | Roche Diagnostics Gmbh | SENSOR WITH IMPROVED BIOKOMPATIBILITY |
US7123206B2 (en) | 2003-10-24 | 2006-10-17 | Medtronic Minimed, Inc. | System and method for multiple antennas having a single core |
US20050090607A1 (en) | 2003-10-28 | 2005-04-28 | Dexcom, Inc. | Silicone composition for biocompatible membrane |
US7299082B2 (en) | 2003-10-31 | 2007-11-20 | Abbott Diabetes Care, Inc. | Method of calibrating an analyte-measurement device, and associated methods, devices and systems |
ES2739529T3 (en) | 2003-11-06 | 2020-01-31 | Lifescan Inc | Drug administration pen with event notification means |
WO2005051170A2 (en) | 2003-11-19 | 2005-06-09 | Dexcom, Inc. | Integrated receiver for continuous analyte sensor |
US7496392B2 (en) | 2003-11-26 | 2009-02-24 | Becton, Dickinson And Company | Fiber optic device for sensing analytes |
US7787923B2 (en) | 2003-11-26 | 2010-08-31 | Becton, Dickinson And Company | Fiber optic device for sensing analytes and method of making same |
US20050148003A1 (en) | 2003-11-26 | 2005-07-07 | Steven Keith | Methods of correcting a luminescence value, and methods of determining a corrected analyte concentration |
US8423114B2 (en) | 2006-10-04 | 2013-04-16 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
US20080197024A1 (en) | 2003-12-05 | 2008-08-21 | Dexcom, Inc. | Analyte sensor |
US8532730B2 (en) | 2006-10-04 | 2013-09-10 | Dexcom, Inc. | Analyte sensor |
DE602004029092D1 (en) | 2003-12-05 | 2010-10-21 | Dexcom Inc | CALIBRATION METHODS FOR A CONTINUOUSLY WORKING ANALYTIC SENSOR |
US8364231B2 (en) | 2006-10-04 | 2013-01-29 | Dexcom, Inc. | Analyte sensor |
US8425417B2 (en) | 2003-12-05 | 2013-04-23 | Dexcom, Inc. | Integrated device for continuous in vivo analyte detection and simultaneous control of an infusion device |
US8425416B2 (en) | 2006-10-04 | 2013-04-23 | Dexcom, Inc. | Analyte sensor |
US20080200788A1 (en) | 2006-10-04 | 2008-08-21 | Dexcorn, Inc. | Analyte sensor |
US8364230B2 (en) | 2006-10-04 | 2013-01-29 | Dexcom, Inc. | Analyte sensor |
US8287453B2 (en) | 2003-12-05 | 2012-10-16 | Dexcom, Inc. | Analyte sensor |
ES2646312T3 (en) | 2003-12-08 | 2017-12-13 | Dexcom, Inc. | Systems and methods to improve electromechanical analyte sensors |
US20050137471A1 (en) | 2003-12-18 | 2005-06-23 | Hans-Peter Haar | Continuous glucose monitoring device |
US20050144450A1 (en) * | 2003-12-30 | 2005-06-30 | Entrust Limited | Method and apparatus for providing mutual authentication between a sending unit and a recipient |
US7384397B2 (en) | 2003-12-30 | 2008-06-10 | Medtronic Minimed, Inc. | System and method for sensor recalibration |
US8230486B2 (en) * | 2003-12-30 | 2012-07-24 | Entrust, Inc. | Method and apparatus for providing mutual authentication between a sending unit and a recipient |
US8394337B2 (en) | 2003-12-31 | 2013-03-12 | Nipro Diagnostics, Inc. | Test strip container with integrated meter |
US20050182451A1 (en) | 2004-01-12 | 2005-08-18 | Adam Griffin | Implantable device with improved radio frequency capabilities |
US7637868B2 (en) | 2004-01-12 | 2009-12-29 | Dexcom, Inc. | Composite material for implantable device |
US7699964B2 (en) | 2004-02-09 | 2010-04-20 | Abbott Diabetes Care Inc. | Membrane suitable for use in an analyte sensor, analyte sensor, and associated method |
US8165651B2 (en) | 2004-02-09 | 2012-04-24 | Abbott Diabetes Care Inc. | Analyte sensor, and associated system and method employing a catalytic agent |
US7364592B2 (en) | 2004-02-12 | 2008-04-29 | Dexcom, Inc. | Biointerface membrane with macro-and micro-architecture |
US20060154642A1 (en) | 2004-02-20 | 2006-07-13 | Scannell Robert F Jr | Medication & health, environmental, and security monitoring, alert, intervention, information and network system with associated and supporting apparatuses |
US7086277B2 (en) | 2004-02-23 | 2006-08-08 | Abbott Laboratories | Device having a flow channel containing a layer of wicking material |
US8808228B2 (en) | 2004-02-26 | 2014-08-19 | Dexcom, Inc. | Integrated medicament delivery device for use with continuous analyte sensor |
US7406105B2 (en) | 2004-03-03 | 2008-07-29 | Alfred E. Mann Foundation For Scientific Research | System and method for sharing a common communication channel between multiple systems of implantable medical devices |
GB0405798D0 (en) * | 2004-03-15 | 2004-04-21 | E San Ltd | Medical data display |
US7228182B2 (en) * | 2004-03-15 | 2007-06-05 | Cardiac Pacemakers, Inc. | Cryptographic authentication for telemetry with an implantable medical device |
WO2005099318A2 (en) | 2004-04-01 | 2005-10-20 | Simona Ioffe | Apparatus for powering an electronic musical instrument |
US7301463B1 (en) | 2004-04-14 | 2007-11-27 | Sage Life Technologies, Llc | Assisting and monitoring method and system |
US20070135697A1 (en) | 2004-04-19 | 2007-06-14 | Therasense, Inc. | Method and apparatus for providing sensor guard for data monitoring and detection systems |
US20050239518A1 (en) | 2004-04-21 | 2005-10-27 | D Agostino Anthony | Systems and methods that provide enhanced state machine power management |
US20080059228A1 (en) * | 2004-04-24 | 2008-03-06 | Christopher Bossi | Operation Of A Remote Medication Management System |
US20050245799A1 (en) | 2004-05-03 | 2005-11-03 | Dexcom, Inc. | Implantable analyte sensor |
US8277713B2 (en) | 2004-05-03 | 2012-10-02 | Dexcom, Inc. | Implantable analyte sensor |
US7651845B2 (en) | 2004-05-13 | 2010-01-26 | The Regents Of The University Of California | Method and apparatus for glucose control and insulin dosing for diabetics |
US7750341B2 (en) * | 2004-05-17 | 2010-07-06 | The Regents Of The University Of California | Bistable nanoparticle-polymer composite for use in memory devices |
US20050261660A1 (en) | 2004-05-24 | 2005-11-24 | Choi Soo B | Method for controlling insulin pump using Bluetooth protocol |
US20050267550A1 (en) | 2004-05-28 | 2005-12-01 | Medtronic Minimed, Inc. | System and method for medical communication device and communication protocol for same |
WO2005119555A2 (en) | 2004-06-01 | 2005-12-15 | Lifescan, Inc. | Methods and systems of automating medical device data management |
US7283867B2 (en) | 2004-06-10 | 2007-10-16 | Ndi Medical, Llc | Implantable system and methods for acquisition and processing of electrical signals from muscles and/or nerves and/or central nervous system tissue |
US20070100222A1 (en) | 2004-06-14 | 2007-05-03 | Metronic Minimed, Inc. | Analyte sensing apparatus for hospital use |
US20060001538A1 (en) * | 2004-06-30 | 2006-01-05 | Ulrich Kraft | Methods of monitoring the concentration of an analyte |
US20060036187A1 (en) | 2004-06-30 | 2006-02-16 | Hester Vos | Devices, systems and methods for extracting bodily fluid and monitoring an analyte therein |
US20060001551A1 (en) | 2004-06-30 | 2006-01-05 | Ulrich Kraft | Analyte monitoring system with wireless alarm |
US8224669B2 (en) * | 2004-07-01 | 2012-07-17 | Anchor Holdings, Inc. | Chronic disease management system |
MXPA06014896A (en) * | 2004-07-01 | 2007-08-20 | Vivomedical Inc | Non-invasive glucose measurement. |
US7719303B2 (en) | 2004-07-06 | 2010-05-18 | Arkray, Inc. | Liquid crystal display device and analysis device including the same |
US20060015020A1 (en) | 2004-07-06 | 2006-01-19 | Dexcom, Inc. | Systems and methods for manufacture of an analyte-measuring device including a membrane system |
US20080242961A1 (en) | 2004-07-13 | 2008-10-02 | Dexcom, Inc. | Transcutaneous analyte sensor |
US8452368B2 (en) | 2004-07-13 | 2013-05-28 | Dexcom, Inc. | Transcutaneous analyte sensor |
WO2006127694A2 (en) | 2004-07-13 | 2006-11-30 | Dexcom, Inc. | Analyte sensor |
US8886272B2 (en) | 2004-07-13 | 2014-11-11 | Dexcom, Inc. | Analyte sensor |
US7783333B2 (en) | 2004-07-13 | 2010-08-24 | Dexcom, Inc. | Transcutaneous medical device with variable stiffness |
US20060016700A1 (en) | 2004-07-13 | 2006-01-26 | Dexcom, Inc. | Transcutaneous analyte sensor |
US7946984B2 (en) | 2004-07-13 | 2011-05-24 | Dexcom, Inc. | Transcutaneous analyte sensor |
US8565848B2 (en) | 2004-07-13 | 2013-10-22 | Dexcom, Inc. | Transcutaneous analyte sensor |
US7344500B2 (en) * | 2004-07-27 | 2008-03-18 | Medtronic Minimed, Inc. | Sensing system with auxiliary display |
US7261691B1 (en) * | 2004-08-02 | 2007-08-28 | Kwabena Asomani | Personalized emergency medical monitoring and transmission system |
US8313433B2 (en) * | 2004-08-06 | 2012-11-20 | Medtronic Minimed, Inc. | Medical data management system and process |
US20060049957A1 (en) | 2004-08-13 | 2006-03-09 | Surgenor Timothy R | Biological interface systems with controlled device selector and related methods |
US20060058602A1 (en) | 2004-08-17 | 2006-03-16 | Kwiatkowski Krzysztof C | Interstitial fluid analyzer |
EP1794695A2 (en) * | 2004-09-23 | 2007-06-13 | Novo Nordisk A/S | Device for self-care support |
US8560041B2 (en) | 2004-10-04 | 2013-10-15 | Braingate Co., Llc | Biological interface system |
US20060173712A1 (en) | 2004-11-12 | 2006-08-03 | Dirk Joubert | Portable medical information system |
US7237712B2 (en) | 2004-12-01 | 2007-07-03 | Alfred E. Mann Foundation For Scientific Research | Implantable device and communication integrated circuit implementable therein |
US20060155338A1 (en) * | 2004-12-20 | 2006-07-13 | Mongeon Luc R | Bi-ventricular ventricular capture management in cardiac resyncronization therapy delivery devices |
US7510526B2 (en) | 2004-12-30 | 2009-03-31 | Medtronic Emergency Response Systems, Inc. | Medical device information system |
WO2006075016A1 (en) * | 2005-01-17 | 2006-07-20 | Novo Nordisk A/S | Fluide delivery device with integrated monitoring of physiological characteristics |
US8934955B2 (en) | 2005-01-18 | 2015-01-13 | Stat Medical Devices, Inc. | Cartridge with lancets and test strips and testing device using the cartridge |
US20060166629A1 (en) | 2005-01-24 | 2006-07-27 | Therasense, Inc. | Method and apparatus for providing EMC Class-B compliant RF transmitter for data monitoring an detection systems |
US20060173498A1 (en) * | 2005-01-31 | 2006-08-03 | Isabelle Banville | Communication between an external defibrillator and an implantable medical device |
US20060178633A1 (en) | 2005-02-03 | 2006-08-10 | Insulet Corporation | Chassis for fluid delivery device |
US7570018B2 (en) | 2005-02-07 | 2009-08-04 | Colgate-Palmolive Co. | Rechargeable powered device |
US20090076360A1 (en) | 2007-09-13 | 2009-03-19 | Dexcom, Inc. | Transcutaneous analyte sensor |
CA2601088C (en) | 2005-03-14 | 2012-04-10 | The Alfred E. Mann Foundation For Scientific Research | System and method for locating objects and communicating with the same |
DE102005013685A1 (en) | 2005-03-18 | 2006-09-28 | Roche Diagnostics Gmbh | Tape magazine for a hand-held device for examining a body fluid, as well as a hand-held device |
WO2006102412A2 (en) | 2005-03-21 | 2006-09-28 | Abbott Diabetes Care, Inc. | Method and system for providing integrated medication infusion and analyte monitoring system |
US8112240B2 (en) | 2005-04-29 | 2012-02-07 | Abbott Diabetes Care Inc. | Method and apparatus for providing leak detection in data monitoring and management systems |
US20060253085A1 (en) | 2005-05-06 | 2006-11-09 | Medtronic Minimed, Inc. | Dual insertion set |
US9233203B2 (en) | 2005-05-06 | 2016-01-12 | Medtronic Minimed, Inc. | Medical needles for damping motion |
US7768408B2 (en) | 2005-05-17 | 2010-08-03 | Abbott Diabetes Care Inc. | Method and system for providing data management in data monitoring system |
US7620437B2 (en) | 2005-06-03 | 2009-11-17 | Abbott Diabetes Care Inc. | Method and apparatus for providing rechargeable power in data monitoring and management systems |
US8565891B2 (en) * | 2005-06-07 | 2013-10-22 | Fractus, S.A. | Wireless implantable medical device |
EP1893079B1 (en) | 2005-06-08 | 2012-06-27 | SHER, Philip Michael | Fluctuating blood glucose notification threshold profiles and methods of use |
US8251904B2 (en) | 2005-06-09 | 2012-08-28 | Roche Diagnostics Operations, Inc. | Device and method for insulin dosing |
US20060293577A1 (en) | 2005-06-23 | 2006-12-28 | Morrison Andrew E | Glucose monitoring kit |
US7480138B2 (en) | 2005-06-30 | 2009-01-20 | Symbol Technologies, Inc. | Reconfigurable mobile device docking cradle |
US7661146B2 (en) * | 2005-07-01 | 2010-02-09 | Privamed, Inc. | Method and system for providing a secure multi-user portable database |
TWI417543B (en) * | 2005-08-05 | 2013-12-01 | Bayer Healthcare Llc | Meters and method of using meters having a multi-level user interface with predefined levels of user features |
US9089713B2 (en) | 2005-08-31 | 2015-07-28 | Michael Sasha John | Methods and systems for semi-automatic adjustment of medical monitoring and treatment |
US8965509B2 (en) | 2005-08-31 | 2015-02-24 | Michael Sasha John | Methods and systems for semi-automatic adjustment of medical monitoring and treatment |
DE502005009907D1 (en) | 2005-09-15 | 2010-08-26 | Roche Diagnostics Gmbh | Insertion head with handle |
US9858433B2 (en) * | 2005-09-16 | 2018-01-02 | Koninklijke Philips N.V. | Cryptographic role-based access control |
US7725148B2 (en) * | 2005-09-23 | 2010-05-25 | Medtronic Minimed, Inc. | Sensor with layered electrodes |
US9072476B2 (en) | 2005-09-23 | 2015-07-07 | Medtronic Minimed, Inc. | Flexible sensor apparatus |
US7756561B2 (en) | 2005-09-30 | 2010-07-13 | Abbott Diabetes Care Inc. | Method and apparatus for providing rechargeable power in data monitoring and management systems |
US20090054747A1 (en) | 2005-10-31 | 2009-02-26 | Abbott Diabetes Care, Inc. | Method and system for providing analyte sensor tester isolation |
US7583190B2 (en) | 2005-10-31 | 2009-09-01 | Abbott Diabetes Care Inc. | Method and apparatus for providing data communication in data monitoring and management systems |
US7766829B2 (en) | 2005-11-04 | 2010-08-03 | Abbott Diabetes Care Inc. | Method and system for providing basal profile modification in analyte monitoring and management systems |
EP3064236B1 (en) | 2005-11-08 | 2020-02-05 | Bigfoot Biomedical, Inc. | Method and system for manual and autonomous control of an infusion pump |
US7595723B2 (en) | 2005-11-14 | 2009-09-29 | Edwards Lifesciences Corporation | Wireless communication protocol for a medical sensor system |
US7704226B2 (en) * | 2005-11-17 | 2010-04-27 | Medtronic Minimed, Inc. | External infusion device with programmable capabilities to time-shift basal insulin and method of using the same |
US20080200838A1 (en) | 2005-11-28 | 2008-08-21 | Daniel Goldberger | Wearable, programmable automated blood testing system |
US7941200B2 (en) * | 2005-12-08 | 2011-05-10 | Roche Diagnostics Operations, Inc. | System and method for determining drug administration information |
US8046069B2 (en) * | 2005-12-22 | 2011-10-25 | Cardiac Pacemakers, Inc. | Method and apparatus for control of cardiac therapy using non-invasive hemodynamic sensor |
US8102789B2 (en) | 2005-12-29 | 2012-01-24 | Medtronic, Inc. | System and method for synchronous wireless communication with a medical device |
US8219129B2 (en) | 2006-01-06 | 2012-07-10 | Proxense, Llc | Dynamic real-time tiered client access |
US20070180259A1 (en) * | 2006-01-20 | 2007-08-02 | Bulot Earl J | Secure Personal Medical Process |
US8344966B2 (en) | 2006-01-31 | 2013-01-01 | Abbott Diabetes Care Inc. | Method and system for providing a fault tolerant display unit in an electronic device |
WO2007088510A1 (en) * | 2006-01-31 | 2007-08-09 | Koninklijke Philips Electronics N.V. | Role-based access control |
US8080003B1 (en) * | 2006-02-02 | 2011-12-20 | Paunceforte Technologies, LLC | Method and implantable apparatus for the intra-osseal monitoring of biological substances in the bone marrow |
AU2007212587B2 (en) * | 2006-02-03 | 2012-07-12 | Synecor, Llc | Intravascular device for neuromodulation |
DE602007013723D1 (en) | 2006-02-09 | 2011-05-19 | Deka Products Lp | SYSTEMS FOR DISPENSING FLUIDS IN PATCH SIZE |
US7981034B2 (en) | 2006-02-28 | 2011-07-19 | Abbott Diabetes Care Inc. | Smart messages and alerts for an infusion delivery and management system |
US20070214497A1 (en) * | 2006-03-10 | 2007-09-13 | Axalto Inc. | System and method for providing a hierarchical role-based access control |
US7618369B2 (en) | 2006-10-02 | 2009-11-17 | Abbott Diabetes Care Inc. | Method and system for dynamically updating calibration parameters for an analyte sensor |
US7801582B2 (en) | 2006-03-31 | 2010-09-21 | Abbott Diabetes Care Inc. | Analyte monitoring and management system and methods therefor |
US8226891B2 (en) | 2006-03-31 | 2012-07-24 | Abbott Diabetes Care Inc. | Analyte monitoring devices and methods therefor |
US20070231846A1 (en) | 2006-04-03 | 2007-10-04 | Cosentino Daniel L | Glucose meter communication method and system |
US8073008B2 (en) | 2006-04-28 | 2011-12-06 | Medtronic Minimed, Inc. | Subnetwork synchronization and variable transmit synchronization techniques for a wireless medical device network |
US8279059B2 (en) * | 2006-06-29 | 2012-10-02 | Given Imaging Ltd. | Data recorder, system and method for transmitting data received from an in-vivo sensing device |
WO2008005843A2 (en) * | 2006-06-30 | 2008-01-10 | Cyberkinetics Neurotechnology Systems, Inc. | Nerve regeneration system and lead devices associated therewith |
US20090105571A1 (en) | 2006-06-30 | 2009-04-23 | Abbott Diabetes Care, Inc. | Method and System for Providing Data Communication in Data Management Systems |
US7911010B2 (en) | 2006-07-17 | 2011-03-22 | Kwj Engineering, Inc. | Apparatus and method for microfabricated multi-dimensional sensors and sensing systems |
US8905999B2 (en) * | 2006-09-01 | 2014-12-09 | Cardiac Pacemakers, Inc. | Method and apparatus for endolymphatic drug delivery |
US20080058678A1 (en) | 2006-09-05 | 2008-03-06 | Shinichi Miyata | Kit for the determination of an analyte in a bodily fluid sample that includes a meter with a display-based tutorial module |
US20080057484A1 (en) | 2006-09-05 | 2008-03-06 | Shinichi Miyata | Event-driven method for tutoring a user in the determination of an analyte in a bodily fluid sample |
US20080083618A1 (en) * | 2006-09-05 | 2008-04-10 | Neel Gary T | System and Methods for Determining an Analyte Concentration Incorporating a Hematocrit Correction |
US7730078B2 (en) * | 2006-09-28 | 2010-06-01 | Honeywell Hommed Llc | Role based internet access and individualized role based systems to view biometric information |
US8298142B2 (en) | 2006-10-04 | 2012-10-30 | Dexcom, Inc. | Analyte sensor |
US8449464B2 (en) | 2006-10-04 | 2013-05-28 | Dexcom, Inc. | Analyte sensor |
US8447376B2 (en) | 2006-10-04 | 2013-05-21 | Dexcom, Inc. | Analyte sensor |
US7831287B2 (en) | 2006-10-04 | 2010-11-09 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
US8562528B2 (en) | 2006-10-04 | 2013-10-22 | Dexcom, Inc. | Analyte sensor |
US8478377B2 (en) | 2006-10-04 | 2013-07-02 | Dexcom, Inc. | Analyte sensor |
US8275438B2 (en) | 2006-10-04 | 2012-09-25 | Dexcom, Inc. | Analyte sensor |
US20080171967A1 (en) * | 2006-10-17 | 2008-07-17 | Blomquist Michael L | Insulin pump having a food database |
US20080172029A1 (en) * | 2006-10-17 | 2008-07-17 | Blomquist Michael L | Insulin pump for determining carbohydrate consumption |
US20080172027A1 (en) * | 2006-10-17 | 2008-07-17 | Blomquist Michael L | Insulin pump having basal rate testing features |
US7515060B2 (en) * | 2006-10-17 | 2009-04-07 | Smiths Medical Md, Inc. | Insulin pump for the visually impaired |
US20080172031A1 (en) * | 2006-10-17 | 2008-07-17 | Blomquist Michael L | Insulin pump having correction factors |
US20080172030A1 (en) * | 2006-10-17 | 2008-07-17 | Blomquist Michael L | Insulin pump having aweekly schedule |
US20080172028A1 (en) * | 2006-10-17 | 2008-07-17 | Blomquist Michael L | Insulin pump having selectable insulin absorption models |
US20080092638A1 (en) | 2006-10-19 | 2008-04-24 | Bayer Healthcare Llc | Wireless analyte monitoring system |
US8131566B2 (en) * | 2006-10-24 | 2012-03-06 | Medapps, Inc. | System for facility management of medical data and patient interface |
US8579853B2 (en) | 2006-10-31 | 2013-11-12 | Abbott Diabetes Care Inc. | Infusion devices and methods |
US7946985B2 (en) | 2006-12-29 | 2011-05-24 | Medtronic Minimed, Inc. | Method and system for providing sensor redundancy |
US8123686B2 (en) | 2007-03-01 | 2012-02-28 | Abbott Diabetes Care Inc. | Method and apparatus for providing rolling data in communication systems |
US20090093687A1 (en) | 2007-03-08 | 2009-04-09 | Telfort Valery G | Systems and methods for determining a physiological condition using an acoustic monitor |
EP1967139A1 (en) | 2007-03-09 | 2008-09-10 | Roche Diagnostics GmbH | Disposable puncturing device and resuable handling device for a puncturing device |
WO2008154312A1 (en) | 2007-06-08 | 2008-12-18 | Dexcom, Inc. | Integrated medicament delivery device for use with continuous analyte sensor |
WO2009029672A1 (en) * | 2007-08-28 | 2009-03-05 | Dds Ventures, Inc. | System and method of dental case management |
US20090063402A1 (en) | 2007-08-31 | 2009-03-05 | Abbott Diabetes Care, Inc. | Method and System for Providing Medication Level Determination |
US8303545B2 (en) | 2007-09-07 | 2012-11-06 | Stat Medical Devices, Inc. | Infusion device and method of using and making the same |
JP5109171B2 (en) | 2007-09-18 | 2012-12-26 | 株式会社ワコム | Position indicator, position input device, and computer system |
US8417312B2 (en) | 2007-10-25 | 2013-04-09 | Dexcom, Inc. | Systems and methods for processing sensor data |
US8290559B2 (en) | 2007-12-17 | 2012-10-16 | Dexcom, Inc. | Systems and methods for processing sensor data |
WO2009097450A1 (en) | 2008-01-30 | 2009-08-06 | Dexcom. Inc. | Continuous cardiac marker sensor system |
US20090299156A1 (en) | 2008-02-20 | 2009-12-03 | Dexcom, Inc. | Continuous medicament sensor system for in vivo use |
WO2009105709A1 (en) | 2008-02-21 | 2009-08-27 | Dexcom, Inc. | Systems and methods for processing, transmitting and displaying sensor data |
US8595026B2 (en) * | 2008-02-21 | 2013-11-26 | Global Health Products, Inc. | System and methods of obtaining reimbursements for patient treatment |
US8396528B2 (en) | 2008-03-25 | 2013-03-12 | Dexcom, Inc. | Analyte sensor |
US20090242399A1 (en) | 2008-03-25 | 2009-10-01 | Dexcom, Inc. | Analyte sensor |
CN102047101A (en) | 2008-03-28 | 2011-05-04 | 德克斯康公司 | Polymer membranes for continuous analyte sensors |
US20100241447A1 (en) * | 2008-04-25 | 2010-09-23 | Polyremedy, Inc. | Customization of wound dressing using rule-based algorithm |
EP2326944B1 (en) | 2008-09-19 | 2020-08-19 | Dexcom, Inc. | Particle-containing membrane and particulate electrode for analyte sensors |
JP5657678B2 (en) | 2009-09-29 | 2015-01-21 | ライフスキャン・スコットランド・リミテッドLifeScan Scotland, Ltd. | Analyte testing method and device for diabetes management |
US8244231B2 (en) * | 2009-09-30 | 2012-08-14 | Research In Motion Limited | Method and apparatus for disambiguating an emergency call attempt during password entry for unlocking a mobile communication device |
CN103051454A (en) * | 2012-12-19 | 2013-04-17 | 天地融科技股份有限公司 | Electronic equipment and password authentication method thereof |
US20150100602A1 (en) * | 2013-10-03 | 2015-04-09 | Amekc Llc | System and method for third party remote access to personal medical records |
US9203814B2 (en) * | 2014-02-24 | 2015-12-01 | HCA Holdings, Inc. | Providing notifications to authorized users |
US10542004B1 (en) * | 2014-02-24 | 2020-01-21 | C/Hca, Inc. | Providing notifications to authorized users |
CN113709244A (en) * | 2015-05-12 | 2021-11-26 | 德克斯康公司 | Distributed system architecture for continuous glucose monitoring |
US9703956B1 (en) * | 2015-06-08 | 2017-07-11 | Symantec Corporation | Systems and methods for categorizing virtual-machine-aware applications for further analysis |
US10642753B1 (en) * | 2015-06-30 | 2020-05-05 | Fireeye, Inc. | System and method for protecting a software component running in virtual machine using a virtualization layer |
US10133866B1 (en) * | 2015-12-30 | 2018-11-20 | Fireeye, Inc. | System and method for triggering analysis of an object for malware in response to modification of that object |
GB2551775A (en) * | 2016-06-30 | 2018-01-03 | Ipco 2012 Ltd | Communications device, point of sale device, payment device and methods |
US10685111B2 (en) * | 2016-10-31 | 2020-06-16 | Crowdstrike, Inc. | File-modifying malware detection |
US10909263B2 (en) * | 2017-01-06 | 2021-02-02 | International Business Machines Corporation | Utilizing a mnemonic for communicating sensitive data |
US10877851B2 (en) * | 2017-03-24 | 2020-12-29 | Commvault Systems, Inc. | Virtual machine recovery point selection |
EP3635667A4 (en) * | 2017-05-18 | 2021-08-25 | Codex LLC | Decentralized digital content distribution system and process using block chains |
US10503904B1 (en) * | 2017-06-29 | 2019-12-10 | Fireeye, Inc. | Ransomware detection and mitigation |
US10635810B2 (en) * | 2018-01-31 | 2020-04-28 | Jungle Disk, L.L.C. | Probabilistic anti-encrypting malware protections for cloud-based file systems |
US10680820B2 (en) * | 2018-03-09 | 2020-06-09 | Coolbitx Ltd. | Method of creating and recovering digital wallet |
US11417109B1 (en) * | 2018-03-20 | 2022-08-16 | Amazon Technologies, Inc. | Network-based vehicle event detection system |
US11288385B2 (en) * | 2018-04-13 | 2022-03-29 | Sophos Limited | Chain of custody for enterprise documents |
US10776482B2 (en) * | 2018-05-18 | 2020-09-15 | International Business Machines Corporation | Automated virtual machine integrity checks |
US10922411B2 (en) * | 2018-06-20 | 2021-02-16 | Malwarebytes Inc. | Intelligent event collection for cloud-based malware detection |
US10970396B2 (en) * | 2018-06-20 | 2021-04-06 | Malwarebytes Inc. | Intelligent event collection for rolling back an endpoint state in response to malware |
EP3847569A4 (en) * | 2018-09-03 | 2022-05-11 | Munia Limited | Management system |
US20200120081A1 (en) * | 2018-10-11 | 2020-04-16 | Ca, Inc. | User authentication based on biometric passwords |
CA3115834A1 (en) * | 2018-10-12 | 2020-04-16 | Zeu Crypto Networks Inc. | Biocrypt digital wallet |
CN109687975B (en) * | 2018-12-29 | 2020-11-03 | 飞天诚信科技股份有限公司 | Method and device for realizing off-line initialization of hardware wallet |
US11522905B2 (en) * | 2019-09-11 | 2022-12-06 | International Business Machines Corporation | Malicious virtual machine detection |
CN111064743B (en) * | 2019-12-28 | 2021-09-28 | 飞天诚信科技股份有限公司 | Method and system for safely inputting password |
US11210658B2 (en) * | 2020-05-12 | 2021-12-28 | iCoin Technology, Inc. | Constructing a distributed ledger transaction on a cold hardware wallet |
-
2006
- 2006-10-31 US US11/555,207 patent/US8579853B2/en active Active
-
2007
- 2007-10-24 BR BRPI0718146-9A2A patent/BRPI0718146A2/en not_active IP Right Cessation
- 2007-10-24 CA CA002667952A patent/CA2667952A1/en not_active Abandoned
- 2007-10-24 CN CNA2007800407139A patent/CN101534883A/en active Pending
- 2007-10-24 WO PCT/US2007/082413 patent/WO2008055037A2/en active Application Filing
- 2007-10-24 EP EP07854392A patent/EP2079500A4/en not_active Withdrawn
- 2007-10-24 JP JP2009535399A patent/JP4908592B2/en active Active
- 2007-10-24 RU RU2009120566/14A patent/RU2009120566A/en not_active Application Discontinuation
- 2007-10-24 MX MX2009004577A patent/MX2009004577A/en unknown
- 2007-10-24 AU AU2007313880A patent/AU2007313880A1/en not_active Abandoned
-
2012
- 2012-01-12 JP JP2012003988A patent/JP2012106001A/en not_active Abandoned
-
2013
- 2013-09-30 US US14/042,629 patent/US9064107B2/en active Active
-
2015
- 2015-06-03 US US14/730,047 patent/US10007759B2/en active Active
-
2018
- 2018-06-25 US US16/017,480 patent/US11043300B2/en active Active
-
2021
- 2021-06-22 US US17/354,343 patent/US11837358B2/en active Active
- 2021-09-01 US US17/464,304 patent/US11508476B2/en active Active
-
2022
- 2022-11-10 US US17/984,524 patent/US20230064839A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US20220013224A1 (en) | 2022-01-13 |
US11043300B2 (en) | 2021-06-22 |
US9064107B2 (en) | 2015-06-23 |
WO2008055037A2 (en) | 2008-05-08 |
CN101534883A (en) | 2009-09-16 |
US8579853B2 (en) | 2013-11-12 |
JP4908592B2 (en) | 2012-04-04 |
AU2007313880A1 (en) | 2008-05-08 |
JP2012106001A (en) | 2012-06-07 |
RU2009120566A (en) | 2010-12-10 |
EP2079500A4 (en) | 2010-02-24 |
WO2008055037A3 (en) | 2008-07-03 |
US20230064839A1 (en) | 2023-03-02 |
US20140033303A1 (en) | 2014-01-30 |
US20080103447A1 (en) | 2008-05-01 |
BRPI0718146A2 (en) | 2013-11-05 |
JP2010508123A (en) | 2010-03-18 |
MX2009004577A (en) | 2009-08-20 |
US11508476B2 (en) | 2022-11-22 |
EP2079500A2 (en) | 2009-07-22 |
US10007759B2 (en) | 2018-06-26 |
US20180308579A1 (en) | 2018-10-25 |
US20210398663A1 (en) | 2021-12-23 |
US20150269340A1 (en) | 2015-09-24 |
US11837358B2 (en) | 2023-12-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US11837358B2 (en) | Infusion devices and methods | |
US20100069732A1 (en) | Medical Devices and Methods of Using the Same | |
US20210236729A1 (en) | Redundant staggered glucose sensor disease management system | |
US10448834B2 (en) | Smart messages and alerts for an infusion delivery and management system | |
US11806110B2 (en) | Method and system for providing data management in integrated analyte monitoring and infusion system | |
US20080119702A1 (en) | Analyte meter having alert, alarm and test reminder capabilities and methods of use | |
TW201535305A (en) | Method and system for management of diabetes with a glucose monitor and infusion pump to provide feedback on bolus dosing | |
AU2013315694A1 (en) | Method and system to indicate glycemic impacts of insulin infusion pump commands |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued |
Effective date: 20131024 |