CA2620500A1 - Lens delivery system - Google Patents
Lens delivery system Download PDFInfo
- Publication number
- CA2620500A1 CA2620500A1 CA002620500A CA2620500A CA2620500A1 CA 2620500 A1 CA2620500 A1 CA 2620500A1 CA 002620500 A CA002620500 A CA 002620500A CA 2620500 A CA2620500 A CA 2620500A CA 2620500 A1 CA2620500 A1 CA 2620500A1
- Authority
- CA
- Canada
- Prior art keywords
- plunger
- wipers
- delivery system
- lens
- lens delivery
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1662—Instruments for inserting intraocular lenses into the eye
- A61F2/167—Instruments for inserting intraocular lenses into the eye with pushable plungers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1662—Instruments for inserting intraocular lenses into the eye
- A61F2/1678—Instruments for inserting intraocular lenses into the eye with a separate cartridge or other lens setting part for storage of a lens, e.g. preloadable for shipping
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00736—Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments
Abstract
A lens delivery system having a plunger rod with a plurality of elastomeric wipers that frictionally and slidably engage the interior bore of the delivery system handpiece.
Alternatively, the elastomeric wipers can be located on the bore and frictionally and slidably engage the plunger rod. The amount of frictional engagement by the wipers can be varied and controlled by adjusting the geometry, size or material properties (modulus of elasticity) of the wipers. The wipers help to provide feedback to the user, and also help provide more even, consistent force throughout the full range of travel of the plunger rod.
Alternatively, the elastomeric wipers can be located on the bore and frictionally and slidably engage the plunger rod. The amount of frictional engagement by the wipers can be varied and controlled by adjusting the geometry, size or material properties (modulus of elasticity) of the wipers. The wipers help to provide feedback to the user, and also help provide more even, consistent force throughout the full range of travel of the plunger rod.
Description
Re: 3234 US ~. j LENS DELIVERY SYSTEM
This invention relates to intraocular lenses (IOLs) and more particularly to devices used to inject IOLs into an eye.
BackRround of the Invention The human eye in its simplest terms functions to provide vision by transmitting and refracting light through a clear outer portion called the cornea, and fnrther focusing the image by way of the lens onto the retina at the back of the eye. The quality of the focused image depends on many factors including the size, shape and length of the eye, and the shape and transparency of the cornea and lens.
When trauma, age or disease cause the lens to become less transparent, vision deteriorates because of the diminished light which can be transmitted to the retina. This is deficiency in the lens of the eye is medically known as a cataract. The treatment for this condition is surgical removal of the lens and implantation of an artificial lens or IOL.
While early IOLs were made from hard plastic, such as polymethylmethacrylate (PMMA), soft, foldable IOLs made from silicone, soft acrylics and hydrogels have become increasingly popular because of the ability to fold or roll these soft lenses and insert them through a smaller incision. Several methods of rolling or folding the lenses are used. One popular method is an injector cartridge.that folds the lenses and provides a relatively small diameter lumen through which the lens may be pushed into the eye, usually by a soft tip plunger. One of the most commonly used injector cartridge design is illustrated in U.S. Patent No. 4,681,102 (Bartell), and includes a split, longitudinally hinged cartridge. Another recently introduced disposable lens delivery system is disclosed in USPN 7,156,854 B2 (Brown, et al.). Other cartridge designs are illustrated in U.S. Patent Nos. 5,494,484 and 5,499,987 (Feingold) and 5,616,148 and 5,620,450 (Eagles, et al.). In an attempt to avoid the claims of U.S. Patent No.
4,681,102, several solid cartridges have been investigated, see for example U.S. Patent No.
5,275,604 (Rheinish, et al.) and 5,653,715 (Reich, et al.).
The ability to express a lens out of a cartridge without damage is dependent on lens design and material. Silicone lenses, being made from a relatively rugged and durable material, can be compressed more aggressively. High water content hydrogel material, being more fragile, must be folded more gently. Soft acrylics, being viscoelastic in nature, are highly sensitive to temperature, and can be brittle if too cold, and can be Re: 3234 US ( t: .
unworkable if too warm. Soft acrylics, when compressed at an appropriate temperature, can be described as "flowing" rather than folding. For this reason, soft acrylics are best compressed slowly and in a very controlled manner.
Prior art lens delivery handpiece suitable for use with soft acrylic IOLs generally have plungers that are either advanced by use of a screw or by pushing on the proximal end of the plunger, similar to the motion used with a syringe. Handpieces having plunger advanced by a screw generally advance the lens in an even, controlled manner.
Syringe-type plunger advancement can be problematic because the tactic feedback from the plunger varies. Initial pressure must be relatively high to overcome the initial resistance of the lens. Once the lens is moving, the required pressure on the Plunger rod to continue to advance the lens will lessen, but then increases gradually as the lens is folded more tightly and enters the narrow, restricted nozzle bore. As a result, it can be difficult to apply slow, even and steady pressure to the plunger rod in syringe-type lens delivery systems.
Accordingly, a need continues to exist for a device to help provide even, consistent tactile feedback to the user of a syringe-type lens injection system.
Brief Summary of the Invention The present invention improves upon prior art by providing a lens delivery system having a plunger rod with a plurality of elastomeric wipers that frictionally and slidably engage the interior bore of the delivery system handpiece. Alternatively, the elastomeric wipers can be located on the bore and frictionally and slidably engage the plunger rod.
The amount of frictional engagement by the wipers can be varied and controlled by adjusting the geometry, size or material properties (modulus of elasticity) of the wipers.
The wipers help to provide feedback to the user, and also help provide more even, consistent force throughout the full range of travel of the plunger rod.
It is accordingly an objective of the present invention to provide a lens delivery system that is suitable for folding lenses made from a soft acrylic material.
It is a further objective of the present invention to provide a lens delivery system having a plurality of internal elastomeric wipers.
It is a further objective of the present invention to provide a lens delivery system that provides a more even, consistent force throughout the full range of travel of the plunger rod.
Other objectives, features and advantages of the present invention will become Re: 3234 US (' ( apparent with reference to the drawings, and the following description of the drawings and claims.
Brief Descrivtion of the Drawings FIG. 1 is a top plan view of the lens delivery system of the present invention.
FIG. 2 is an enlarged partial top plan view of one embodiment of the lens delivery system of the present invention taken at circle 2 in FIG. 1.
FIG. 3 is an enlarged partial perspective view of one embodiment of a plunger that io may bc used with the lens delivery system of the present invention.
Detailed Description of the Preferred Embodiments As best seen in FIG. 1, lens delivery system 10 of the present invention generally 1s includes lens delivery cartridge 12, tubular handpiece 14 and plunger 16.
Handpiece 14 may be of any suitable construction, such as molded thermoplastic or machined aluminum, stainless steel or titanium. Cartridge 12 generally has tubular body 18 and injection nozzle 20. Cartridge 12 is molded as a single piece from any suitable thermoplastic, such as polypropylene, and the thermoplastic may contain a lubricity 20 enhancing agent such as those disclosed in U.S. Pat. No. 5,716,364, the entire contents of which are incorporated herein by reference. Alternatively, cartridge 12 may be integrally formed with handpiece 14. Nozzle 20 preferably is round, oval or elliptical in cross-section and has a cross-sectional area of between around 1.0 mm2 to around 2.6 mm2. An intraocular lens (not shown) is pushed out of cartridge 12 and down nozzle 18 by plunger 25 16 in a manner well-known in the art.
As best seen in FIG. 3, plunger 16 generally contains a proximal thicken portion 22 having proximal cap 24 and distally extending plunger rod 26. Plunger rod 26 is thinner than thicken portion 22 and sized and shaped to reciprocate within nozzle 20.
Plunger 16 is sized and shaped to reciprocate within handpiece 14 and may contain 30 additional features, such as stop 28 to help prevent movement of plunger 16 within handpiece 14 so that, for example, pushing on cap 24 propels plunger rod into and down nozzle 20 while stop 28 prevents plunger rod 26 from being drawn back out of nozzle 20.
Thickened portion 22 of plunger 16 may contain a plurality of elastomeric wipers 30 that frictionally engage the interior wall of tubular body 14. Such frictional 35 engagement increases the force required to push plunger 16 within tubular body 14. One Re: 3234 US
skilled in the art will recognize that the amount of force can be controlled by increasing the number and/or size of wipers 30 or by varying the material properties, such as modulus of elasticity, of wipers 30. Although wipers 30 increase the force required to push plunger 16 within tubular body 14, wipers 30 also help to provide feedback to the user, and help provide more even, consistent force throughout the full range of travel of plunger 16. Wipers 30 can be attached to plunger 16 in any suitable manner, such as over-molding. Preferably, wipers 30 extend only partially along or around thickened portion 22 of plunger 16.
Alternatively, as seen in FIGS. 1 and 2, wipers 30' can be attached to interior wall 32 of tubular handpiece 14. Wipers 30' are of similar construction as wipers 30 and attached to interior wall 32 of tubular handpiece 14 in a manner similar to that used to attach wipers 30 to plunger 16.
While certain embodiments of the present invention have been described above, these descriptions are given for purposes of illustration and explanation.
Variations, changes, modifications and departures from the systems and methods disclosed above may be adopted without departure from the scope or spirit of the present invention.
This invention relates to intraocular lenses (IOLs) and more particularly to devices used to inject IOLs into an eye.
BackRround of the Invention The human eye in its simplest terms functions to provide vision by transmitting and refracting light through a clear outer portion called the cornea, and fnrther focusing the image by way of the lens onto the retina at the back of the eye. The quality of the focused image depends on many factors including the size, shape and length of the eye, and the shape and transparency of the cornea and lens.
When trauma, age or disease cause the lens to become less transparent, vision deteriorates because of the diminished light which can be transmitted to the retina. This is deficiency in the lens of the eye is medically known as a cataract. The treatment for this condition is surgical removal of the lens and implantation of an artificial lens or IOL.
While early IOLs were made from hard plastic, such as polymethylmethacrylate (PMMA), soft, foldable IOLs made from silicone, soft acrylics and hydrogels have become increasingly popular because of the ability to fold or roll these soft lenses and insert them through a smaller incision. Several methods of rolling or folding the lenses are used. One popular method is an injector cartridge.that folds the lenses and provides a relatively small diameter lumen through which the lens may be pushed into the eye, usually by a soft tip plunger. One of the most commonly used injector cartridge design is illustrated in U.S. Patent No. 4,681,102 (Bartell), and includes a split, longitudinally hinged cartridge. Another recently introduced disposable lens delivery system is disclosed in USPN 7,156,854 B2 (Brown, et al.). Other cartridge designs are illustrated in U.S. Patent Nos. 5,494,484 and 5,499,987 (Feingold) and 5,616,148 and 5,620,450 (Eagles, et al.). In an attempt to avoid the claims of U.S. Patent No.
4,681,102, several solid cartridges have been investigated, see for example U.S. Patent No.
5,275,604 (Rheinish, et al.) and 5,653,715 (Reich, et al.).
The ability to express a lens out of a cartridge without damage is dependent on lens design and material. Silicone lenses, being made from a relatively rugged and durable material, can be compressed more aggressively. High water content hydrogel material, being more fragile, must be folded more gently. Soft acrylics, being viscoelastic in nature, are highly sensitive to temperature, and can be brittle if too cold, and can be Re: 3234 US ( t: .
unworkable if too warm. Soft acrylics, when compressed at an appropriate temperature, can be described as "flowing" rather than folding. For this reason, soft acrylics are best compressed slowly and in a very controlled manner.
Prior art lens delivery handpiece suitable for use with soft acrylic IOLs generally have plungers that are either advanced by use of a screw or by pushing on the proximal end of the plunger, similar to the motion used with a syringe. Handpieces having plunger advanced by a screw generally advance the lens in an even, controlled manner.
Syringe-type plunger advancement can be problematic because the tactic feedback from the plunger varies. Initial pressure must be relatively high to overcome the initial resistance of the lens. Once the lens is moving, the required pressure on the Plunger rod to continue to advance the lens will lessen, but then increases gradually as the lens is folded more tightly and enters the narrow, restricted nozzle bore. As a result, it can be difficult to apply slow, even and steady pressure to the plunger rod in syringe-type lens delivery systems.
Accordingly, a need continues to exist for a device to help provide even, consistent tactile feedback to the user of a syringe-type lens injection system.
Brief Summary of the Invention The present invention improves upon prior art by providing a lens delivery system having a plunger rod with a plurality of elastomeric wipers that frictionally and slidably engage the interior bore of the delivery system handpiece. Alternatively, the elastomeric wipers can be located on the bore and frictionally and slidably engage the plunger rod.
The amount of frictional engagement by the wipers can be varied and controlled by adjusting the geometry, size or material properties (modulus of elasticity) of the wipers.
The wipers help to provide feedback to the user, and also help provide more even, consistent force throughout the full range of travel of the plunger rod.
It is accordingly an objective of the present invention to provide a lens delivery system that is suitable for folding lenses made from a soft acrylic material.
It is a further objective of the present invention to provide a lens delivery system having a plurality of internal elastomeric wipers.
It is a further objective of the present invention to provide a lens delivery system that provides a more even, consistent force throughout the full range of travel of the plunger rod.
Other objectives, features and advantages of the present invention will become Re: 3234 US (' ( apparent with reference to the drawings, and the following description of the drawings and claims.
Brief Descrivtion of the Drawings FIG. 1 is a top plan view of the lens delivery system of the present invention.
FIG. 2 is an enlarged partial top plan view of one embodiment of the lens delivery system of the present invention taken at circle 2 in FIG. 1.
FIG. 3 is an enlarged partial perspective view of one embodiment of a plunger that io may bc used with the lens delivery system of the present invention.
Detailed Description of the Preferred Embodiments As best seen in FIG. 1, lens delivery system 10 of the present invention generally 1s includes lens delivery cartridge 12, tubular handpiece 14 and plunger 16.
Handpiece 14 may be of any suitable construction, such as molded thermoplastic or machined aluminum, stainless steel or titanium. Cartridge 12 generally has tubular body 18 and injection nozzle 20. Cartridge 12 is molded as a single piece from any suitable thermoplastic, such as polypropylene, and the thermoplastic may contain a lubricity 20 enhancing agent such as those disclosed in U.S. Pat. No. 5,716,364, the entire contents of which are incorporated herein by reference. Alternatively, cartridge 12 may be integrally formed with handpiece 14. Nozzle 20 preferably is round, oval or elliptical in cross-section and has a cross-sectional area of between around 1.0 mm2 to around 2.6 mm2. An intraocular lens (not shown) is pushed out of cartridge 12 and down nozzle 18 by plunger 25 16 in a manner well-known in the art.
As best seen in FIG. 3, plunger 16 generally contains a proximal thicken portion 22 having proximal cap 24 and distally extending plunger rod 26. Plunger rod 26 is thinner than thicken portion 22 and sized and shaped to reciprocate within nozzle 20.
Plunger 16 is sized and shaped to reciprocate within handpiece 14 and may contain 30 additional features, such as stop 28 to help prevent movement of plunger 16 within handpiece 14 so that, for example, pushing on cap 24 propels plunger rod into and down nozzle 20 while stop 28 prevents plunger rod 26 from being drawn back out of nozzle 20.
Thickened portion 22 of plunger 16 may contain a plurality of elastomeric wipers 30 that frictionally engage the interior wall of tubular body 14. Such frictional 35 engagement increases the force required to push plunger 16 within tubular body 14. One Re: 3234 US
skilled in the art will recognize that the amount of force can be controlled by increasing the number and/or size of wipers 30 or by varying the material properties, such as modulus of elasticity, of wipers 30. Although wipers 30 increase the force required to push plunger 16 within tubular body 14, wipers 30 also help to provide feedback to the user, and help provide more even, consistent force throughout the full range of travel of plunger 16. Wipers 30 can be attached to plunger 16 in any suitable manner, such as over-molding. Preferably, wipers 30 extend only partially along or around thickened portion 22 of plunger 16.
Alternatively, as seen in FIGS. 1 and 2, wipers 30' can be attached to interior wall 32 of tubular handpiece 14. Wipers 30' are of similar construction as wipers 30 and attached to interior wall 32 of tubular handpiece 14 in a manner similar to that used to attach wipers 30 to plunger 16.
While certain embodiments of the present invention have been described above, these descriptions are given for purposes of illustration and explanation.
Variations, changes, modifications and departures from the systems and methods disclosed above may be adopted without departure from the scope or spirit of the present invention.
Claims (4)
1. An intraocular lens delivery system, comprising:
a) a cartridge;
b) a tubular handpiece having an interior wall;
c) a plunger having a distally extending plunger rod attached to a proximal thickened portion, the plunger being sized and shaped to reciprocate within the tubular handpiece; and d) at least one wiper attached to the thicken portion of the plunger so as to frictionally engage the interior wall of the tubular handpiece.
a) a cartridge;
b) a tubular handpiece having an interior wall;
c) a plunger having a distally extending plunger rod attached to a proximal thickened portion, the plunger being sized and shaped to reciprocate within the tubular handpiece; and d) at least one wiper attached to the thicken portion of the plunger so as to frictionally engage the interior wall of the tubular handpiece.
2. The lens delivery system of claim 1 wherein the wiper is made from an elastomeric material.
3. An intraocular lens delivery system, comprising:
a) a cartridge;
b) a tubular handpiece having an interior wall;
c) a plunger having a distally extending plunger rod attached to a proximal thickened portion, the plunger being sized and shaped to reciprocate within the tubular handpiece; and d) at least one wiper attached to the interior wall of the tubular handpiece so as to frictionally engage the thicken portion of the plunger.
a) a cartridge;
b) a tubular handpiece having an interior wall;
c) a plunger having a distally extending plunger rod attached to a proximal thickened portion, the plunger being sized and shaped to reciprocate within the tubular handpiece; and d) at least one wiper attached to the interior wall of the tubular handpiece so as to frictionally engage the thicken portion of the plunger.
4. The lens delivery system of claim 1 wherein the wiper is made from an elastomeric material.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/675,402 | 2007-02-15 | ||
US11/675,402 US20080200921A1 (en) | 2007-02-15 | 2007-02-15 | Lens Delivery System |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2620500A1 true CA2620500A1 (en) | 2008-08-15 |
Family
ID=39361764
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002620500A Abandoned CA2620500A1 (en) | 2007-02-15 | 2008-02-08 | Lens delivery system |
Country Status (13)
Country | Link |
---|---|
US (1) | US20080200921A1 (en) |
EP (1) | EP1958594A1 (en) |
JP (1) | JP2008194478A (en) |
KR (1) | KR20080076837A (en) |
CN (1) | CN101243997A (en) |
AR (1) | AR065375A1 (en) |
AU (1) | AU2008200717A1 (en) |
BR (1) | BRPI0800212A (en) |
CA (1) | CA2620500A1 (en) |
IL (1) | IL189436A0 (en) |
MX (1) | MX2008002091A (en) |
RU (1) | RU2375992C2 (en) |
TW (1) | TW200843708A (en) |
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US5716364A (en) * | 1996-07-10 | 1998-02-10 | Allergan | IOL insertion apparatus and method for making and using same |
JP2000152989A (en) * | 1998-11-19 | 2000-06-06 | Bracco Internatl Bv | Injector and cartridge and plunger ring therefor |
FR2789890B1 (en) * | 1999-02-22 | 2002-01-18 | Lab Contactologie Appl Lca | DEVICE FOR INJECTING AN INTRAOCULAR LENS IN FLEXIBLE MATERIAL |
JP4138428B2 (en) * | 2002-09-27 | 2008-08-27 | 株式会社ニデック | Intraocular lens insertion device |
US7156854B2 (en) * | 2003-05-28 | 2007-01-02 | Alcon, Inc. | Lens delivery system |
FR2875125B1 (en) * | 2004-09-13 | 2006-12-01 | Patrick Meunier | DEVICE FOR LOADING AN INTRAOCULAR LENS IN AN INJECTION CARTRIDGE |
CN101068507B (en) * | 2004-11-30 | 2010-05-12 | 博士伦公司 | Two-stage plunger for intraocular lens injector |
US7740636B2 (en) * | 2005-04-15 | 2010-06-22 | Abbott Medical Optics Inc. | Multi-action device for inserting an intraocular lens into an eye |
-
2007
- 2007-02-15 US US11/675,402 patent/US20080200921A1/en not_active Abandoned
-
2008
- 2008-02-08 CA CA002620500A patent/CA2620500A1/en not_active Abandoned
- 2008-02-08 EP EP08101441A patent/EP1958594A1/en not_active Withdrawn
- 2008-02-11 IL IL189436A patent/IL189436A0/en unknown
- 2008-02-13 MX MX2008002091A patent/MX2008002091A/en not_active Application Discontinuation
- 2008-02-14 RU RU2008105731/14A patent/RU2375992C2/en not_active IP Right Cessation
- 2008-02-14 AU AU2008200717A patent/AU2008200717A1/en not_active Abandoned
- 2008-02-14 TW TW097105144A patent/TW200843708A/en unknown
- 2008-02-15 KR KR1020080013950A patent/KR20080076837A/en not_active Application Discontinuation
- 2008-02-15 CN CNA2008100881615A patent/CN101243997A/en active Pending
- 2008-02-15 JP JP2008034768A patent/JP2008194478A/en active Pending
- 2008-02-15 BR BRPI0800212-6A patent/BRPI0800212A/en not_active IP Right Cessation
- 2008-02-15 AR ARP080100661A patent/AR065375A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
RU2008105731A (en) | 2009-08-20 |
TW200843708A (en) | 2008-11-16 |
JP2008194478A (en) | 2008-08-28 |
EP1958594A1 (en) | 2008-08-20 |
US20080200921A1 (en) | 2008-08-21 |
AR065375A1 (en) | 2009-06-03 |
RU2375992C2 (en) | 2009-12-20 |
MX2008002091A (en) | 2009-02-25 |
IL189436A0 (en) | 2008-11-03 |
CN101243997A (en) | 2008-08-20 |
AU2008200717A1 (en) | 2008-09-04 |
KR20080076837A (en) | 2008-08-20 |
BRPI0800212A (en) | 2008-10-07 |
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Legal Events
Date | Code | Title | Description |
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EEER | Examination request | ||
FZDE | Discontinued |